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2009 International Symposium on Micro-NanoMechatronics and Human Science最新文献

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MEMS with five senses for IRT 具有五感IRT的MEMS
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5352101
I. Shimoyama
IRT is a new technological domain created by the integration of Information Technology (IT), which encompasses high-speed computing and network and software technologies, and Robot Technology (RT), whose forms and movements function in the physical world. IT, formed from technologies of the cyber-world, has the power to process information in the real world through communication and computer technologies. It promises to have even more advanced capabilities in the future. RT, formed from the technologies of the physical world, has advanced greatly in reliability and real-world functionality. By integration IT and RT, IRT innovations promise to give birth to industries that support life and society, and to bring about social transformation. One of the killer applications of IRT is a kitchen robot. The robot we have developed has tactile sensors to deal with plates and glasses on a tray and put them into a dishwasher. The tactile sensors are molded by elastic materials with tiny cantilevers in it. Not only tactile sensors but also vision/acoustic sensors are necessary for motion, safety and reliability of household robots. MEMS (MicroElectroMechanical Systems) give tiny/thin sensor arrays which cover a robot as smart skin.
IRT是包含高速计算、网络和软件技术的信息技术(IT)与形式和运动在物理世界中起作用的机器人技术(RT)相结合而形成的新技术领域。信息技术由网络世界的技术形成,具有通过通信和计算机技术处理现实世界信息的能力。它承诺在未来拥有更先进的功能。RT是由物理世界的技术形成的,在可靠性和现实世界的功能方面有了很大的进步。通过IT和RT的融合,IRT创新有望催生支持生活和社会的产业,并带来社会变革。IRT的杀手级应用之一是厨房机器人。我们开发的机器人有触觉传感器,可以处理托盘上的盘子和玻璃杯,并将它们放入洗碗机。触觉传感器是由带有微小悬臂的弹性材料制成的。为了保证家用机器人的运动、安全、可靠,不仅需要触觉传感器,还需要视觉/声学传感器。MEMS(微机电系统)提供微小/薄的传感器阵列,覆盖机器人作为智能皮肤。
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引用次数: 0
Adsorbed surfactant thickness on: A Si wafer dominating etching properties of TMAH solution 硅片表面活性剂的厚度决定了TMAH溶液的蚀刻性能
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5352098
B. Tang, M. Gosálvez, P. Pal, S. Itoh, H. Hida, M. Shikida, Kazuo Sato
The goal of this article is to study the etching properties as a function of various adsorbed surfactant thickness in wet anisotropic etching process of TMAH solution. The thickness of preferentially adsorbed surfactant molecules on Si{110} and Si{100} has been evaluated by using spectroscopic ellipsometry (SE). The dependence of the etch rate in TMAH and the surface roughness on the layer thickness demonstrates that the surfactant is adsorbed at the interface during etching in TMAH+Triton. A thin pre-adsorbed layer is sufficient to dramatically improve the etching characteristics of silicon.
本文的目的是研究TMAH溶液湿法各向异性刻蚀过程中不同表面活性剂厚度对刻蚀性能的影响。利用椭圆偏振光谱(SE)研究了表面活性剂分子在Si{110}和Si{100}表面的优先吸附厚度。TMAH中蚀刻速率和表面粗糙度随层厚的变化关系表明,表面活性剂在TMAH+Triton中蚀刻时被吸附在界面上。薄的预吸附层足以显著改善硅的蚀刻特性。
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引用次数: 5
Pico-liter injection control to individual nano-liter solution coated by lipid layer 微升注射控制到单个纳升溶液涂有脂质层
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351948
Y. Matsuno, M. Nakajima, M. Kojima, Y. Tanaka-Takiguchi, K. Takiguchi, K. Nogawa, M. Homma, T. Fukuda
This paper presents the evaluation of ultra-minimal spout amount from micro-nano pipettes into phospholipid-coated micro-droplets. The pipettes can be used to control the local environment around/inside single cells. Conventionally, the microinjection with pipette has been conducted by air pressures. In this method, the spout of high viscosity solutions is difficult because of the frictional forces between the surface of a pipette and a solution. It is also needed to evaluate the spout amount quantitatively. On the other hand, the research about artificial cell model has been actively conducted, injecting various biological samples into liposomes which are vesicle of lipid bilayer membrane. If additional injection of various proteins into liposome is realized with micro/nano pipette, the observation of dynamic reaction of multiple biological samples, which is required for formulation of artificial cell, will become possible. In our research, the spouting method using electro-osmosis is used. The local spouts of the proteins such as GFP and F-actin have been presented experimentally before. In this paper, the amount of spout solution in this method is quantitatively evaluated by injection of fluorescent solution into a phospholipid-coated micro-droplet.
本文介绍了从微纳移液器到磷脂包被微液滴的超最小喷出量的评价。移液器可用于控制单个细胞周围/内部的局部环境。传统上,用移液管进行显微注射是在气压下进行的。在这种方法中,由于移液管表面和溶液之间的摩擦力,高粘度溶液的喷射是困难的。还需要定量地评价喷淋量。另一方面,积极开展人工细胞模型的研究,将各种生物样品注射到脂质体中,脂质体是脂质双层膜的囊泡。如果用微纳移液器实现脂质体中各种蛋白的附加注射,就可以观察多种生物样品的动态反应,这是制备人工细胞所需要的。在我们的研究中,采用电渗透的喷射方法。GFP和f -肌动蛋白等蛋白的局部喷口已经在实验中被发现。本文通过将荧光溶液注射到磷脂包被的微滴中,定量地评价了该方法的喷液量。
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引用次数: 3
Characterization of the piezoresistive effect and temperature coefficient of resistance in single crystalline silicon nanowires 单晶硅纳米线压阻效应及电阻温度系数的表征
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351972
T. Bui, D. Dao, K. Nakamura, T. Toriyama, S. Sugiyama
This paper reports the design, fabrication and evaluation of piezoresistive effect of the top-down fabricated p-type <110> Si Nanowires (SiNWs). The SiNWs with the length of 2µm, thickness of 35nm and width ranges from 35nm to 490nm have been fabricated by electron beam (EB) direct writing and reactive ion etching (RIE). The impurity concentration of the SiNWs is 2×1018 cm−3, obtained by ion implantation. The SiNWs are protected by a thermally grown SiO2 to avoid the environment influence and to deactivate the outer layer, which was attacked during RIE process. Dependence of piezoresistive effects on the width of the SiNWs of both longitudinal and transverse SiNWs has been characterized. The significant increasing had been found in longitudinal piezoresistive coefficient πl[110]. The results showed that when the width of the SiNWs reduces to nanometer size, the smaller the width, the bigger the piezoresistive coefficient. The coefficient πl[110] along <110> crystallographic orientation increased up to 60% when the width of SiNWs down from 490nm to 35nm. Furthermore, rather small influence of temperature to piezoresistive coefficient has been characterized. Piezoresistive effect slightly decreases when the temperature increases. The temperature coefficient of resistance (TCR) of the SiNWs has been measured to be from 450 to 850ppm/°C, i.e. about 8 times smaller than that of bulk silicon at same doping concentration. These excellent characteristics are important for high sensitive and low-temperature-affected mechanical sensors.
本文报道了自上而下制备p型硅纳米线的设计、制作和压阻效应评价。采用电子束(EB)直接写入和反应离子刻蚀(RIE)法制备了长2µm、厚35nm、宽35nm ~ 490nm的SiNWs。离子注入得到的SiNWs杂质浓度为2×1018 cm−3。sinw由热生长的SiO2保护,以避免环境的影响,并使在RIE过程中受到攻击的外层失活。研究了压阻效应对纵向和横向SiNWs宽度的影响。纵向压阻系数πl显著增大[110]。结果表明:当SiNWs的宽度减小到纳米尺寸时,宽度越小,压阻系数越大;当SiNWs的宽度从490nm减小到35nm时,沿晶体取向的πl系数[110]增大了60%。此外,温度对压阻系数的影响很小。当温度升高时,压阻效应略有降低。在相同掺杂浓度下,SiNWs的电阻温度系数(TCR)在450 ~ 850ppm/°C之间,比本体硅小约8倍。这些优异的特性对于高灵敏度和低温影响的机械传感器非常重要。
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引用次数: 12
Fabrication of biodegradable scaffold by powder sintering process 粉末烧结法制备可生物降解支架
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351879
T. Itoyama, T. Nakano, S. Ikeda, T. Fukuda, T. Matsuda, M. Negoro, F. Arai
To reproduce blood vessel, we proposed new process for fabricating biodegradable scaffold by powder sintering process. In this process, model for molding scaffold was materialized by rapid prototyping. Biodegradable polymer powder and porogen were dusted to model and heated. So, arbitrary shape scaffold would be fabricated. Also, porosity that influences compliance of blood vessel scaffold would be adjusted by changing ratio of the polymer powder and porogen. We studied fabrication condition of blood vessel scaffold by measuring porosity and Young's modulus when the ratio of the polymer powder and porogen was adjusted. Also, HUVECs were cultured on the scaffold, and the scaffold's biocompatibility was confirmed.
为了复制血管,我们提出了粉末烧结法制备生物可降解支架的新工艺。在此过程中,采用快速成型技术实现了支架成型模型的物化。将可生物降解的聚合物粉末和多孔材料撒入模型并加热。因此,任意形状的支架将被制造出来。通过改变聚合物粉末与孔隙率的比例,调节孔隙率对血管支架顺应性的影响。通过测量聚合物粉末与孔隙率配比不同时的孔隙率和杨氏模量,研究了血管支架的制备条件。并在支架上培养huvec,证实支架的生物相容性。
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引用次数: 0
Development of evolutionary and self-assembling robot-organisms 进化和自组装机器人有机体的发展
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5352063
P. Levi
Symbiotic robotics is a discipline within collective robotics that is concerned with artificial multi-cellular robot-organisms that define their morphological structure by aggregation through self-assembling and they are also able to disaggregate afterwards. This contribution is concerned to the description of evolutionary and cognitive principles that governs such a symbiotic cycle to build artificial organisms of different forms and operate with them. The evolutionary approach starts with a artificial genome, will be continued by the insertion of different types of regulative cycles, and ends up in an embryogenetic formed body. Hereby there is differentiation between the genetic based learning and the fitness based learning. Further there are dominant differences between multi-cellular organism and structured cooperative aggregations of swarm members. The cognitive approach is focused on cognitive maps, on cognitive sensor data fusion and finally to the definition of information that governs the the process of organism formation and body survival in a given environment. This more engineering oriented approach is used to build all HW-components and all kinds of embedded “operating systems” to control and to operate symbiotic robot organisms.
共生机器人是集体机器人中的一门学科,它涉及人工多细胞机器人有机体,这些机器人有机体通过自组装的聚集来定义其形态结构,并且之后也能够分解。这一贡献涉及对进化和认知原则的描述,这些原则支配着这种共生循环,以建立不同形式的人工生物体并与它们一起运作。进化的方法从人工基因组开始,将通过插入不同类型的调节周期继续下去,最终形成胚胎形成的身体。因此,基于遗传的学习和基于适应度的学习是有区别的。此外,多细胞生物与群体成员的结构化合作群体之间存在显著差异。认知方法侧重于认知地图,认知传感器数据融合,并最终定义在给定环境中控制生物体形成和身体生存过程的信息。这种更具工程导向的方法用于构建所有hw组件和各种嵌入式“操作系统”,以控制和操作共生机器人有机体。
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引用次数: 0
Manipulating behaviors of targeted single cells in vivo by using IR-LEGO 利用IR-LEGO在体内操纵目标单细胞的行为
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351899
Motoshi Suzuki, Y. Kamei, S. Yuba, S. Takagi
Methods for turning on/off gene expression at any desired time and place in vivo would be useful for analyzing various biological processes. We have developed a novel microscopic system utilizing an infrared laser, IR-LEGO (infrared-laser evoked gene operator), which is designed to deposit heat locally in living organisms. We have shown that IR-LEGO enables us to induce the heat shock response efficiently in targeted single cells of C. elegans worms, thereby driving expression of a transgene under the control of a heat shock promoter. By using IR-LEGO we attempted to rescue several mutant phenotypes of worms at the single-cell level. Diverse cell behaviors including differentiation and migration of target cells can be manipulated by gene induction mediated by IR-LEGO. Our results showed that IR-LEGO can be used to manipulate cell-autonomous as well as cell-nonautonomous behaviors, further confirming that irradiation using IR-LEGO has no harmful effects on the targets. Thus, IR-LEGO serves as valuable tools for manipulating biological processes in living organisms.
在体内任意时间和地点开启/关闭基因表达的方法将有助于分析各种生物过程。我们开发了一种利用红外激光器的新型显微系统,IR-LEGO(红外激光诱发基因操作符),旨在将热量局部沉积在生物体中。我们已经证明,IR-LEGO使我们能够在秀丽隐杆线虫的靶单细胞中有效地诱导热休克反应,从而在热休克启动子的控制下驱动转基因的表达。通过IR-LEGO,我们试图在单细胞水平上挽救几种蠕虫的突变表型。IR-LEGO介导的基因诱导可以调控靶细胞的分化和迁移等多种细胞行为。我们的研究结果表明,IR-LEGO可以用来操纵细胞自主和细胞非自主行为,进一步证实了使用IR-LEGO照射对靶标没有有害影响。因此,IR-LEGO可作为操纵生物体生物过程的宝贵工具。
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引用次数: 0
Development of the maskless photolithography device with an LCD-projector for fabrication of micropatterned surfaces 带lcd投影仪的无掩模光刻装置的研制
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351890
K. Itoga, J. Kobayashi, M. Yamato, T. Okano
We developed the maskless photolithography device by modifying the optical system of an LCD projector and applied to cell micropatterning and fabrication of microchannels. Furthermore, we also developed the second-generation device allows for the fabrication of micropatterns over a larger area (over 50 × 50 mm). The maskless system has the big merit that doesn't need a photomask. However, there are a few problems in the maskless system. One of them is that patterns of segmentalized boundaries with an XY stage get out of shape. It is caused by optical distortion, precision of XY stage and so on. To overcome the defect, we have developed a third-generation device equipped with a more precision XY-stage and invented a method to improve patterns of divided edge by multiphase exposure. We were able to improve patterns of divided edge by the method.
我们通过改进LCD投影机的光学系统,开发了无掩模光刻装置,并将其应用于细胞微图像化和微通道的制造。此外,我们还开发了第二代设备,允许在更大的区域(超过50 × 50毫米)上制造微图案。无掩模系统的一大优点是不需要掩模。然而,无掩模系统也存在一些问题。其中之一是带有XY阶段的分割边界模式会变形。它是由光学畸变、XY台精度等因素引起的。为了克服这一缺陷,我们开发了配备更精确的x -stage的第三代器件,并发明了一种通过多相曝光改善分边图案的方法。用该方法改进了分边图案。
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引用次数: 0
On-chip particle-laden droplet dispensing by disposable inkjet system 一次性喷墨系统的片上微粒负载液滴点胶
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351878
T. Mizunuma, Y. Yamanishi, S. Sakuma, H. Maruyama, F. Arai
We succeeded in dispensing micro-droplet by a disposable on-chip inkjet mechanism. Novelty of this paper is summarized as follows. (1) We employed a glass plate bonded Poly-dimethylsiloxane (PDMS) membrane to obtain leaf spring structure whose spring coefficient is 14 times of the conventional PDMS membrane. As a result, we succeeded in dispensing droplets continuously (up to 10 Hz) by vibrating the membrane using the multilayers piezoelectric actuator attached to the PDMS disposable chip. (2) The nozzle for droplet dispensing was fabricated by thick photoresist (SU-8) to obtain the hydrophobic surface which prevents any undesired satellite droplets produced. Consequently the accuracy of position of the droplet dispensing was achieved ± 5 μm. The size of the droplet produced from the disposable nozzle (diameter = 100 μm) was in the range of 95–105 μm at the applied voltage of 105 V.
我们成功地利用一次性片上喷墨机构进行微滴点胶。本文的新颖性总结如下。(1)采用玻璃板粘结聚二甲基硅氧烷(PDMS)膜,得到弹簧系数为常规PDMS膜14倍的钢板弹簧结构。结果,我们成功地通过使用附着在PDMS一次性芯片上的多层压电致动器振动膜来连续点胶液滴(高达10 Hz)。(2)采用厚光刻胶(SU-8)制作液滴点胶喷嘴,获得疏水表面,防止产生不需要的卫星液滴。结果表明,液滴点胶的位置精度为±5 μm。在105 V电压下,一次性喷嘴(直径为100 μm)产生的液滴尺寸在95 ~ 105 μm之间。
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引用次数: 2
Microactuator using tensile thin film 微致动器采用拉伸薄膜
Pub Date : 2009-12-11 DOI: 10.1109/MHS.2009.5351764
M. Sasaki
The thin film is advantageous for preparing the compliant spring and structures with little mass. The surface micromachining can take these advantages. Since the film structures suffer from the bending generated by the stress imbalance inside, the bulk micromachining is now frequently used. When the tensile stress is introduced in the thin film combining with bulk micromachining, the structural robustness will be obtained. As for the torsion bar, the compliant spring performance can be obtained for the twisting motion keeping the rigidity against the other motions. The potentials are indicated with the micromirror. The performances of the low-voltage driving, temperature stability, possibility for increasing the resonant frequency by decreasing the mass of the moving element, and the wireless driving using the subtle energy generated by the electromagnetic induction are confirmed.
该薄膜有利于制备柔性弹簧和小质量结构。表面微加工可以利用这些优点。由于薄膜结构受到内部应力不平衡产生的弯曲的影响,体微加工现在被广泛使用。在薄膜中引入拉应力并结合体微加工,可获得结构的鲁棒性。对于扭杆,在扭转运动中可以获得柔顺弹簧性能,对其他运动保持刚度。电势用微镜显示。验证了其低压驱动性能、温度稳定性、通过减小运动元件质量提高谐振频率的可能性以及利用电磁感应产生的微小能量进行无线驱动的可行性。
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引用次数: 0
期刊
2009 International Symposium on Micro-NanoMechatronics and Human Science
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