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2018 IEEE Micro Electro Mechanical Systems (MEMS)最新文献

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Pattern projector using superposition of double microlens arrays for hybrid 3D endoscope 混合三维内窥镜双微透镜阵列叠加投影
Pub Date : 2018-01-21 DOI: 10.1109/MEMSYS.2018.8346578
Sung-Pyo Yang, Jae-Bum Kim, K. Jeong
This work reports the superposition of double microlens arrays (MLAs) to generate high-density irregular dot pattern projector for hybrid three-dimensional endoscope. MLAs were fabricated on a large scale with thermoplastic photoresist (PR) with Teflon coating and additional parylene coating to have high fill-factor and curvature. Fabricated MLAs were aligned with dynamic rotation between them to generate high-density diffraction pattern with uniformity using monochromatic laser light source. With projected structured laser pattern, 3D object with no texture on its surface was able to calculate the gradually changing disparity values along the object surface.
本文报道了双微透镜阵列(MLAs)的叠加产生用于混合三维内窥镜的高密度不规则点图案投影仪。采用热塑性光刻胶(PR)涂覆聚四氟乙烯和附加聚对二甲苯涂层,大规模制备了具有高填充系数和高曲率的MLAs。利用单色激光光源对制备的MLAs进行动态旋转排列,形成高密度、均匀的衍射图样。利用投影的结构化激光图案,可以计算出表面无纹理的三维物体沿物体表面逐渐变化的视差值。
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引用次数: 6
Ultra sensitive optomechanical microdisk resonators with very large scale integration process 具有超大规模集成工艺的超灵敏光机械微盘谐振器
Pub Date : 2018-01-21 DOI: 10.1109/MEMSYS.2018.8346687
M. Hermouet, M. Sansa, L. Banniard, A. Fafin, M. Gely, P. Allain, E. G. Santos, I. Favero, T. Alava, G. Jourdan, S. Hentz
Nano-optomechanical resonators have demonstrated in the last few years their enormous potential for applications such as mass and chemical sensing. Operation in liquid of such resonators has been demonstrated very recently by two groups, showing that biosensing could potentially be performed. Nonetheless, going a step further towards the next generation of high-end biosensors requires scaling up the fabrication process and being able to perform this type of measurement routinely. This paper reports the first Very Large Scale Integration silicon optomechanical microdisk resonators with state-of-the-art performance: high optical-Q and optomechanical coupling allow the Brownian noise of these resonators to be easily resolved at few 100 MHz in ambient air with many different devices and we show how optical performance is maintained in liquid.
在过去的几年里,纳米光机械谐振器已经证明了它们在质量和化学传感等应用方面的巨大潜力。最近,两组研究人员已经证明了这种谐振器在液体中的操作,表明生物传感有可能实现。尽管如此,向下一代高端生物传感器迈进一步,需要扩大制造过程,并能够进行常规测量。本文报道了第一个具有最先进性能的超大规模集成硅光机械微盘谐振器:高光学q和光机械耦合允许这些谐振器的布朗噪声在环境空气中使用许多不同的设备在很少的100 MHz下很容易地被解决,我们展示了如何在液体中保持光学性能。
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引用次数: 3
Wireless closed-loop control of centrifugo-pneumatic valving towards large-scale microfluidic process integration 面向大规模微流控过程集成的离心-气动阀无线闭环控制
Pub Date : 2018-01-21 DOI: 10.1109/MEMSYS.2018.8346781
D. Kinahan, S. M. Delgado, Lourdes Albina Nirupa Julius, Adam J. Mallette, David Saenz-Ardila, Rohit Mishra, C. Miyazaki, J. Korvink, D. Mager, J. Ducrée
We present for the first time an integrated wirelessly powered Arduino processor and Bluetooth interface that are co-rotated with the cartridge to allow large-scale process integration on a centrifugal microfluidic platform. This highly modular, electronically controlled “Lab-on-a-Disc” system (eLoaD) can independently actuate up to 128 normally-closed valves by an array of microheaters during rotation for comprehensive, highly parallelized sample-to-answer automation. Additionally, we implement real-time optical (colour intensity) measurement for closed-loop control of liquid handling, sample preparation and detection.
我们首次提出了一个集成的无线供电的Arduino处理器和蓝牙接口,它们与卡带共旋转,允许在离心微流控平台上进行大规模的过程集成。这种高度模块化的电子控制“盘上实验室”系统(eLoaD)可以在旋转过程中通过一系列微加热器独立驱动多达128个常闭阀,实现全面、高度并行的样品到答案自动化。此外,我们实现实时光学(色彩强度)测量,用于液体处理,样品制备和检测的闭环控制。
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引用次数: 3
First microphones based on an in-plane deflecting micro-diaphragm and piezoresistive nano-gauges 第一个基于面内偏转微膜片和压阻式纳米计的麦克风
Pub Date : 2018-01-21 DOI: 10.1109/MEMSYS.2018.8346531
H. Lhermet, T. Verdot, A. Berthelot, B. Desloges, F. Souchon
For the first time, functional in-plane deflection microphones have been fabricated, validating a new concept based on a diaphragm moving in the plane of the substrate and inducing strain on piezoresistive Si nano-gauges. Such architecture, integrating furthermore a back cavity, leads to microphones with a smaller footprint that preserve at the same time high performance, and is therefore adapted for the achievement of miniature sensors and their integration for medical applications or consumer electronics.
我们首次制造出了功能面内偏转麦克风,验证了一种基于膜片在衬底平面内移动并在压阻式硅纳米片上感应应变的新概念。这种结构进一步集成了后腔,使麦克风的占地面积更小,同时保持了高性能,因此适用于实现微型传感器及其医疗应用或消费电子产品的集成。
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引用次数: 6
Laser-actuated centrifugo-pneumatic flow control towards ‘sample-to-answer’ integrated detection of multi-marker panels at the point-of-care 激光驱动的离心机-气动流量控制对多标记板在护理点的“样品到答案”集成检测
Pub Date : 2018-01-21 DOI: 10.1109/MEMSYS.2018.8346774
Rohit Mishra, Glen Reilly, M. Agnew, Alexander Garvey, C. Rogers, Elaine Andrade, Hui Ma, Sean M. Fitzgerald, Julia Zapatero, R. O’Kennedy, J. Ducrée
Point-of-care diagnostics devices require user-friendly automation of multi-step / multi-reagent bioana-lytical protocols. We demonstrate, for the first time, Laser-actuated, Centrifugo-Pneumatic Valves (LCPVs) which open on-demand by ablating a remotely connected polymeric membrane with an instrument-based laser. Due to its small footprint, isolation of radiation-induced heating from the biological fluids and independence of radial position & contact-angle, the novel LCPV technology enables large-scale integration of flexibly customizable and operationally robust centrifugal microfluidic “Lab-on-a-Disc” (LoaD) systems. As a pilot application, we demonstrate the detection of Fatty Acid Binding Protein and Myeloperoxidase, both potential biomarkers used for cardiovascular disease (CVD) determination.
即时诊断设备需要用户友好的多步骤/多试剂生物分析协议自动化。我们首次展示了激光驱动的离心气动阀(LCPVs),该阀通过基于仪器的激光烧烧远程连接的聚合物膜来按需打开。由于其占地面积小,与生物流体的辐射加热隔离,并且与径向位置和接触角无关,新型LCPV技术可以大规模集成灵活定制且操作稳健的离心微流体“盘上实验室”(LoaD)系统。作为试点应用,我们展示了脂肪酸结合蛋白和髓过氧化物酶的检测,这两种潜在的生物标志物用于心血管疾病(CVD)的检测。
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引用次数: 3
Microneedle-based system for minimally invasive continuous monitoring of glucose in the dermal interstitial fluid 用于真皮间质液中葡萄糖的微创连续监测的微针系统
Pub Date : 2018-01-01 DOI: 10.1109/MEMSYS.2018.8346574
F. Ribet, G. Stemme, N. Roxhed
We present a minimally invasive continuous glucose monitoring (CGM) device. The system consists in an ultra-miniaturized electrochemical sensor probe (70 × 700 × 50 μm3) inserted into the lumen of a hollow silicon microneedle. The implantable portion of the system is 50-fold smaller than state-of-the-art commercial products, thus enabling glucose monitoring in the dermis and a less invasive insertion procedure. Passive interstitial fluid extraction is achieved, making the daily use of this system practically viable. Moreover, the sensor positioning provides minimal delay in tracking glycaemia (5–10 minutes lag), due to the minimal distance between sensing electrodes and microneedle opening. The demonstrated system has therefore the potential to enable minimally invasive, fast and reliable CGM in patients affected by diabetes.
我们提出了一种微创连续血糖监测(CGM)设备。该系统由一个超小型化的电化学传感器探头(70 × 700 × 50 μm3)组成,探头插入空心硅微针的管腔中。该系统的可植入部分比最先进的商业产品小50倍,因此可以在真皮层进行葡萄糖监测,并且侵入性更小。实现了被动间质液提取,使该系统的日常使用切实可行。此外,由于传感电极和微针开口之间的距离最小,传感器定位在跟踪血糖方面提供了最小的延迟(5-10分钟)。因此,该演示系统有可能为糖尿病患者实现微创、快速和可靠的CGM。
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引用次数: 7
Sulfonation of Poly(phthalazinone ether ketone) for MEMS humidity sensor MEMS湿度传感器用聚酞嗪酮磺化研究
Pub Date : 2018-01-01 DOI: 10.1109/MEMSYS.2018.8346605
Xiaohui Leng, Yiming Wang, Fei Wang
A simple sulfonation process for Poly(phthalazinone ether ketone) (PPEK) was proposed with concentrated sulfonic acid. Various degrees of sulfonation (DS) were realized through the control of reaction time and temperature. Then, sulfonated PPEK (SPPEK) was applied in humidity sensors with MEMS electrodes. Both spray-coating and drop-casting methods were used to optimize the sensing performance. DS influence on the behavior of humidity sensors was investigated with the optimum coating method.
提出了用浓磺酸进行聚酞嗪酮(PPEK)磺化的简单工艺。通过控制反应时间和温度,实现了不同程度的磺化反应。然后,将磺化PPEK (SPPEK)应用于MEMS电极湿度传感器。采用喷涂和滴铸两种方法对传感性能进行优化。采用最佳镀膜方法研究了DS对湿度传感器性能的影响。
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引用次数: 0
Soft X-ray-charged multilayered piezoelectret with embedded electrode for push-button energy harvesting 带有嵌入式电极的软x射线多层压电体,用于按钮能量收集
Pub Date : 1900-01-01 DOI: 10.1109/MEMSYS.2018.8346637
Jia Lu, Yuji Suzuki
In this report, we propose a push-button-type kinetic energy harvester using a soft-X-ray-charged multilayered piezoelectret. With the aid of embedded electrodes, the bias voltage is directly applied to each unit cell. With our 9-layer early prototype, output power of 9.9 μJ has been obtained for 0.75 mm displacement within 0.3 s. d33 as high as 14000 pC/N is realized, which is 10 times higher than that for previous piezoelectrets. Power generation by pushing with a finger has also been demonstrated.
在本报告中,我们提出了一种使用软x射线带电多层压电体的按钮式动能收集器。借助嵌入式电极,将偏置电压直接施加到每个单元电池上。利用我们的9层早期原型,在0.3 s. d33内,在0.75 mm的位移范围内获得了9.9 μJ的输出功率,高达14000 pC/N,比以前的压电体提高了10倍。用手指推动发电也得到了证明。
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引用次数: 0
Gas sensor based on a metal oxide nanowire forest built on a suspended carbon nano-heater 基于悬浮碳纳米加热器上的金属氧化物纳米线森林的气体传感器
Pub Date : 1900-01-01 DOI: 10.1109/MEMSYS.2018.8346703
Y. Lim, Seungwoo Lee, Yeong Min Kwon, J. M. Baik, Heungjoo Shin
This paper reports a novel metal oxide nanowire (MOx NW) based gas senor built on a suspended carbon nanowire heater allowing ultra-low power consumption. This sensing platform was fabricated using only wafer level batch fabrication processes such as carbon-MEMS, atomic layer deposition, and hydrothermal growth processes. Owing to the mechanical rigidity, the suspended carbon nanowire allows selective circumferential growth of MOx NWs on its surface. The suspended carbon NW and MOx NWs are electrically separated with a thin HfO2 layer. In addition, the suspended high-aspect-ratio geometry of the carbon NW enables MOx NWs to be heated with ultra-low power Joule heating. The architecture of the suspended nanowire forest ensures efficient gas access to the sensing sites, detecting NO2 as low as 100 ppb.
本文报道了一种基于悬浮碳纳米线加热器的新型金属氧化物纳米线(MOx NW)气体传感器,该传感器具有超低功耗。该传感平台仅采用碳- mems、原子层沉积和水热生长等晶圆级批量制造工艺制造。由于机械刚性,悬浮碳纳米线允许MOx NWs在其表面选择性周向生长。悬浮碳NW和MOx NWs被一层薄薄的HfO2层电分离。此外,碳NW的悬浮高长宽比几何结构使MOx NW可以用超低功率焦耳加热。悬浮纳米线森林的结构确保气体有效进入传感点,检测低至100 ppb的二氧化氮。
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引用次数: 4
Microneedle roller electrode array (M-REA): A new tool for in vivo low-voltage electric gene delivery 微针滚轮电极阵列(M-REA):一种体内低压基因传递的新工具
Pub Date : 1900-01-01 DOI: 10.1109/MEMSYS.2018.8346572
D. Huang, Deyao Zhao, Yuanyu Huang, Zicai Liang, Zhihong Li
This paper reports a novel device, so-called microneedle roller electrode array (M-REA), for minimally invasive in vivo electric gene delivery, which utilizes parallel circular blades with microneedle arrays on the edge as electrodes. The microneedle arrays are fabricated by planar laser micromachining. Owing to reduced resistance by penetrating stratum corneum and small gaps between electrodes, electric gene delivery by electroporation can be achieved under low voltage. Additionally, our device provides ability of large area electroporation and causes less damage on the target tissue, benefiting from rolling operation, less invasiveness, good biocompatibility and low voltage. Furthermore, low cost fabrication and convenient operation offer vast potential for practical clinical applications.
本文报道了一种新型装置,称为微针滚轮电极阵列(M-REA),用于微创体内电基因传递,该装置利用边缘有微针阵列的平行圆形叶片作为电极。采用平面激光微加工技术制备了微针阵列。由于电穿孔穿透角质层的阻力小,电极间的间隙小,可以在低电压下实现电基因的传递。此外,我们的设备提供大面积电穿孔的能力,对目标组织的损伤较小,有利于滚动操作,侵入性小,生物相容性好,电压低。此外,低成本的制造和方便的操作为实际临床应用提供了巨大的潜力。
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引用次数: 3
期刊
2018 IEEE Micro Electro Mechanical Systems (MEMS)
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