Sensing and Bio-Sensing Research最新文献

The design and analysis of gas detection chips directly affect their detection efficiency and applicability. Detection devices are currently restricted by detection principles, facing drawbacks like intricate structural design, limited applicability, and low detection efficiency. We have designed a complete set of design and analysis scheme for a peptide gas detection chip. First, we selected specific and high-affinity peptide combinations from existing peptide-gas affinity datasets. Then, the peptide chip's arrangement was grouped according to the variations in peptides' affinity towards different gases. Peptides were arranged based on their affinity levels within each group, striking a balance between discrimination and flexibility in the design of the chip. Finally, we evaluated the analysis methods by generating simulated data based on a reference affinity matrix constructed from actual data. Due to the preprocessing role of chip design on affinity data, all methods can effectively accomplish gas classification. In gas concentration prediction tasks, our method reduced mean square error to 0.41, significantly outperforming other methods. This gas detection scheme shortens the development cycle of chip design and analysis methods, fully utilizing the specificity of peptides, enhancing gas analysis effectiveness, and demonstrating the agile development of gas detection chips.

In this study, Sediment Microbial Fuel Cells (SMFCs) prototypes have been developed to operate under open-air conditions and power sensors for environmental monitoring. Two SMFCs with a volume of 50 l each, consisting of two types of anodic materials – graphite and coke, were operated on-field for over a year. The electrical outputs have been recorded and compared with the measured environmental parameters such as temperature, light illumination, atmospheric pressure, humidity, etc. The statistical analysis of the obtained data shows that temperature changes between 0 and 14 °C do not affect the power achieved. On the contrary, the sunlight irradiation showed a second-order polynomial correlation with the current generated by the SMFCs, increasing the latter during the days. The cathode reactions significantly impacted the power density achieved by both explored SMFCs and the system's sustainability. The metallurgical coke is suggested to be used as an inexpensive and convenient anode material for SMFCs giving compatible results to the widely used graphite.

Due to the global pandemic of influenza and related respiratory diseases, rapid and accurate detection is in high demand to control virus spread and facilitate early treatment. However, most current molecular detection methods either require long turnaround times, suffer from low sensitivity and/or can only detect single pathogens. To overcome these challenges, we constructed a novel colorimetric gold nanoparticle (AuNPs) biosensor containing functionalized probes to detect multiple targets simultaneously. Utilizing the salt aging method, AuNPs were functionalized by the designed oligonucleotides to fabricate biosensors. This biosensor can show visible color change within 20 min, and could minimally detect the target influenza viruses at 10 nM. This detection technique presents high sensitivity in a short time, meanwhile identifying two different influenza viruses simultaneously. It opens a window to a multiplex-in-one strategy for a clinical viral diagnostic.

Chemical submission, a nefarious tactic increasingly employed in criminal activities, has spurred urgent calls for innovative countermeasures. GHB, often dubbed “liquid ecstasy,” stands out as a favoured agent for its surreptitious nature and seamless solubility in water and alcoholic beverages. Addressing this menace head-on, a groundbreaking study delves into the development of advanced chemosensors, leveraging 2-aminonaphtoxazole- and benzoxazole-based compounds adorned with fluorescein, to construct a cellulose paper-based detection system. This ingenious setup not only detects GHB in water but extends its vigilance to real alcoholic and non-alcoholic beverages, illuminating a pathway to thwart potential assailants. With a fluorescence enhancement mechanism at play, the system boasts a dynamic range from 0 to 125 mM GHB in water, exhibiting a commendable limit of detection (LOD) at 7.3 mM. Crucially, its eco-friendly nature, devoid of solvent residuals, underscores its suitability as a proactive shield against chemical submission, embodying a beacon of hope in the fight against such insidious threats to public safety.