Advanced Fiber Materials最新文献

The precise and rapid detection of micro-ribonucleic acid (microRNA) in the incipient stages of cancer can effectively elucidate the pathogenesis, migration, and development of tumors. Most of the current microRNA detection methods require large quantities of purified samples, labeling, extended incubation times, and cell lysis, leading to complex procedures that demand labor-intensive preparations and stringent experimental conditions. In this work, we develop a portable and multifunctional biosensor based on an optical microfiber for the detection of microRNA in the early stages of cancer. An innovative graphene oxide-supported bimetallic nanorod (GO-Au NR-Ag NR) interface is engineered on the surface of the optical microfiber to enhance sensor sensitivity for the early detection of ultralow concentrations of microRNA and to integrate cell lysis capabilities. With the enhancement of interface, the sensor is able to detect microRNA-21 at concentrations ranging from 10 zmol/L to 0.1 nmol/L, with a limit of detection (LOD) of 0.25 amol/L. It is also capable of detecting microRNA-21 in body fluids, such as sweat and serum, with LODs of 0.5 amol/L and 0.9 amol/L, respectively. The nano-interface enables the use of photothermal effects by the microfiber to lyse cells and directly detect intracellular microRNA-21, significantly reducing sample extraction time and simplifying the extraction and detection process. This work provides a portable, ultrasensitive, compact, efficient, and non-invasive tool for point-of-care testing.

The rapid advancement of wearable electronics has driven significant interest in the development of wearable energy storage technologies. Among them, aqueous zinc ion batteries (ZIBs) have gained considerable attention as promising candidates for portable and wearable applications. In particular, aqueous fiber-shaped ZIBs offer distinctive advantages, such as miniaturization, flexibility, and wearability, making them especially suitable for powering next-generation wearable devices. This review provides a comprehensive overview of the recent advances in aqueous fiber-shaped ZIBs, focusing on the fabrication of fiber-based electrodes and various battery configurations. In addition, we highlight the evolution of fiber-shaped ZIBs from single-function to multi-function systems, exploring their potential for diverse applications. The review also addresses the key challenges in this field and discusses future research directions to drive the further development of aqueous fiber-shaped ZIBs.

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Traditional antibiotic-based therapies for treating infectious wounds often face challenges in balancing long-term biosafety, promoting wound healing, and effectively eradicating bacteria. Herein, we introduce an innovative "top-down" approach to fabricating one-dimensional (1D) pristine silk nanofibers (SNFs) by the gradual exfoliation of silk fibers, preserving their inherent semi-crystalline structure. These SNFs functioned as a robust template for the in situ growth of two-dimensional (2D) plum blossom-like bismuth nanosheets (BiNS), whose anisotropic morphology enhances bactericidal contact efficiency. The resulting BiNS-equipped SNFs (SNF@Bi) are assembled into membranes (SNFM@Bi) via vacuum filtration, showing superior biocompatibility, photothermal efficiency, and photodynamic activity. Furthermore, the acidic wound microenvironment or near-infrared (NIR) irradiation triggered the release of Bi³⁺, exhibiting nanoenzyme-mediated catalytic activity. This multimodal mechanism allows SNFM@Bi to eliminate over 99% of Staphylococcus aureus and 100% of Escherichia coli by disrupting biofilms, inducing lysis, and causing oxidative damage. In vivo evaluations demonstrated significant bacteria clearance, accelerated angiogenesis, and enhanced collagen deposition, contributing to rapid wound healing without systemic toxicity. Notably, SNFM@Bi detaches spontaneously after healing, avoiding chronic nanomaterial retention risks. This multifunctional antimicrobial platform offers a controllable, effective, and biocompatible therapeutic strategy for antimicrobial dressing design, with potential applications in biomedicine, environmental protection, and public health.

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Flexible strain sensors are revolutionizing human–machine interactions and next-generation health care by enabling real-time monitoring of human motion and precision medical treatment. However, developing lightweight flexible strain sensors that combine high sensitivity with a broad monitoring range remains a significant challenge. To address this challenge, an advanced structural engineering strategy based on the sodium chloride (NaCl) template sacrificial method is employed to simultaneously increase sensitivity and mechanical robustness. By leveraging a NaCl template sacrificial method, a hierarchical synergistic conductive network is constructed within the thermoplastic polyurethane (TPU) matrix formed via in situ growth. This design enables ultra-high sensitivity across a broad strain range, offering promising potential for wearable sensing applications. The resulting sensor exhibits exceptional performance characteristics, including a low detection limit (0.176%), high sensitivity (gage factor, GF = 331.7), wide sensing range (up to 230.1%), rapid response/recovery times (133 ms/133 ms), and remarkable durability exceeding 4000 cycles. Furthermore, the sensor demonstrated excellent electrothermal conversion performance with a positive temperature coefficient of 0.00207 °C⁻¹ and an achievable saturation temperature of 54.2 °C (1.0 A). Finally, the sensor was successfully integrated into a smart wearable system, enabling precise recognition and classification of multiple gestures through machine learning algorithms while also exhibiting significant potential for inflammation hyperthermia therapy.

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Biodegradable and biocompatible organic polymers play a pivotal role in designing the next generation of wearable smart electronics, reducing electronic waste and carbon emissions while promoting a toxin-free environment. Herein, an electrospun fibrous polyhydroxybutyrate (PHB) organic mat-based, energy-autonomous, skin-adaptable temperature sensor is developed, eliminating the need for additional storage or circuit components. The electrospun PHB mat exhibits an enhanced β-crystalline phase with a β/α phase ratio of 3.96 using 1,1,1,3,3,3-hexafluoro-2-propanol as a solvent. Solvent and film processing techniques were tailored to obtain high-quality PHB films with the desired thickness, flexibility, and phase conversion. The PHB mat-based temperature sensor (PHB–TS) exhibits a negative temperature coefficient of resistance, with a sensitivity of − 2.94%/°C and a thermistor constant of 4676 K, outperforming pure metals and carbon-based sensors. A triboelectric nanogenerator (TENG) based on the enhanced β-phase PHB mat was fabricated, delivering an output of 156 V, 0.43 µA, and a power density of 1.71 mW/m². The energy-autonomous PHB–TS was attached to the index finger to monitor temperature changes upon contact with hot and cold surfaces, demonstrating good reliability and endurance.

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As an emerging nanomaterial, nanofibrous aerogel possesses advantages such as low density, large specific surface area, low thermal conductivity, and high mechanical stability. Preparing nanofiber aerogels through electrospinning is an emerging research topic. This review focuses on the key fabrication techniques for electrospun nanofibrous aerogels, including freeze-drying, direct electrospinning, layer-by-layer stacking, and thermally induced self-agglomeration. In addition, by combining nanofibers’ distinctive properties and aerogels’ physical characteristics, nanofibrous aerogels demonstrate various potential academic and industrial applications, including thermal insulation, sound absorption, solar desalination, air filtration, oil–water separation, and biomedical engineering. This paper provides an overview of the fundamentals and recent advancements in electrospinning, summarizes the fabrication methods and applications of the most representative nanofibrous aerogels in recent years, and offers insights into nanofibrous aerogels’ challenges and prospects.

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Peripheral nerve injury presents a significant clinical challenge due to the limited regenerative capacity of the injured nerves, often resulting in permanent functional deficits. A key obstacle to effective nerve regeneration is the inability to modulate the inflammatory response, guide axonal elongation, and promote myelination. To address these challenges, we developed a multi-channel nerve guidance conduit (NGC) that integrated immune-modulating drug with gradient cues to enhance peripheral nerve regeneration. The inner tubes of the conduit were composed of degradable electrospun gelatin methacryloyl/collagen (GelMA/COL) fibers loaded with 1400W, an inducible nitric oxide synthase (iNOS) inhibitor. The outer tube consisted of electrospun polycaprolactone (PCL) fibers decorated with a density gradient of collagen particles encapsulating acidic fibroblast growth factor (aFGF). The release of 1400W enhanced macrophage activity and promoted their polarization from the pro-inflammatory M1 phenotype to the reparative M2 phenotype, thereby creating a pro-regenerative microenvironment conducive to nerve repair. The incorporation of gradient cues guided and promoted Schwann cell migration and neurite extension in vitro. In a rat sciatic nerve injury model, the conduit significantly improved nerve regeneration by sequentially modulating the inflammatory response and guiding axonal elongation, providing both spatial support and biological activity. Furthermore, the conduit promoted organized nerve fiber alignment, enhanced myelination, and achieved functional recovery outcomes that closely resembled those of the autograft. These findings suggest that the integration of immune-regulatory drug release, gradient cues, and a multi-channel structure presents a promising strategy for enhancing peripheral nerve repair.

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Flexible photodetectors are ideal for short-range communication in lightweight microintegrated systems. However, low-bonding interface and high-power cost of photosensitive components greatly limit their application in flexible communication systems. To address this, herein, piezophototronic effect-enhanced sensing components are proposed for flexible photodetectors. This approach leverages the piezophototronic effect to modulate nanoscale charge transport and the precision of electrohydrodynamic direct-writing to achieve controlled nanofiber assembly, thereby enhancing interfacial bonding and overall device performance. By employing electrohydrodynamic direct-writing, a copper-ammonia complex ((Cu(NH₃))(CN)) nanofiber is self-stacked on a zinc oxide (ZnO) nanofiber to construct a zinc oxide and copper ammine complex (ZnO@(Cu(NH₃))(CN)) photodetector with low static power consumption and high responsiveness through the combined effects of piezoelectricity and fiber self-stacking. The dark current is reduced to 1.12 × 10⁻⁷ A, and the static power consumption of the photodetector is also decreased. The responsiveness is up to 13.3 A/W, with response and recovery times of 11 and 9 ms under ultraviolet (UV) light illumination, respectively, fulfilling the requirements for highly sensitive photodetection owing to the high interface bonding. The detector's threshold voltage is tunable, ranging from 6 V for 5 stacking layers to 20 V for 25 stacking layers, thereby allowing the device's performance to be precisely tailored to specific application requirements. Leveraging the exceptional optoelectronic performance of the ZnO@(Cu(NH₃))(CN) photodetector, this study expands the application scenarios of flexible photodetectors and demonstrates their potential in the fields of 6G technology and battlefield communication.

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Electrocaloric (EC) polymers have garnered significant attention in recent years due to their zero direct greenhouse gas emissions during cooling processes. However, only a few polymers exhibit sufficient refrigeration capacity at low fields, which limits the application of the EC cooling technology. In this work, we show that electrospinning, a mature polymer processing technology, can introduce a complex fibrous matrix that leads to nano-, meso-, and micro-scale structures, and hence a series of hierarchical polar interfaces. The following thermal treatment was applied to enhance breakdown fields and reduce dielectric losses. A series of polyvinylidene fluoride (PVDF)-based fluoropolymers containing cellulose acetate (CA) were prepared. By introducing 10 wt% of CA, the electrospinning process significantly improves the polar entropy of the fluoropolymer system and significantly improves the polymer’s breakdown strength, polarization, and electrocaloric performances, compared to their solution cast counterparts. The polar entropy variations among various polymeric composites were elucidated using data acquired from multiple structural characterization tools. By linking the optimized hierarchical interface structures and the overall EC performances, this study provides new routes for designing high-performance EC nanocomposites that can be facilely tailored by the matured processes of fibrous, polymeric composites.

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Piezoelectric filler-based composite fiber sensors have emerged as promising candidates for wearable textiles due to their self-powered capability and excellent sensing performance. However, current spinning fabrication methods face significant challenges in achieving uniform distribution and optimal orientation of piezoelectric fillers within polymer matrices, which limits their sensing performance. To address these issues, an innovative electric-assisted coaxial wet spinning method is developed to fabricate piezoelectric composite fiber (denoted as P-B fiber), which was composed of boron nitride nanosheets (BNNSs) as piezoelectric fillers and polyvinylidene fluoride (PVDF) as a piezoelectric polymer matrix. The radial electric field applied during spinning promotes the radial orientation of BNNSs, leading to enhanced stress transfer efficiency and, as a result, improved piezoelectricity. Moreover, the radial electric field enables the simultaneous in-situ polarization of BNNSs and PVDF during spinning process, further improving the piezoelectric performance. As a result, the P-B fiber exhibits an exceptional piezoelectric sensitivity of (186.4 ± 1.1) mV/N, approximately sixfold higher than that of fibers produced without electric field assistance. Accordingly, the P-B fiber demonstrates remarkable capability in detecting tiny mechanical loads, such as pulse waves and respiration, making it particularly suitable for wearable physiological monitoring textiles, providing a promising strategy for developing high-performance piezoelectric fiber sensors.

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