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Nutrition Clinique et Metabolisme最新文献

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Nutritional practices in medical intensive care units: Multicenter, one-day point prevalence study 医疗重症监护病房的营养实践:多中心,为期一天的点患病率研究
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.06.002
Leyla Ferlicolak , Neriman Defne Altintas , Burcin Halacli , Sahin Temel , Ozlem Cakin , Melda Turkoglu , Bilgin Comert , Gurhan Taskin , Avsar Zerman , Turkay Akbas , Emre Karakoc , Kamil Gonderen , Ismail Hakkı Akbudak , Kursat Gundogan , Arzu Topeli

Background/Aim

Nutritional planning is an important aspect of Intensive Care Unit (ICU) care. The present study aimed to evaluate the nutritional practices adopted in medical ICUs in Turkiye and to investigate their compliance with current international guidelines.

Methods

This multicenter, cross-sectional study was performed on a predetermined study date. Centers were required to fill three groups of questionnaires: One on ICU characteristics and facilities, one on patients included, and one on outcomes of patients. Forms on patients had questions on demographics and their nutritional status.

Results

A total of 12 sites participated and 132 patients were recorded in the study and 109 patients were included in analyses. The median age was 72 [57–83] years and 55 (50%) of them was female. The median APACHE II score was 23 [18–29], median SOFA score was 6 [4–9] and median BMI was 25.32 [21.22–29.38]. More than 50% of patients were fed enterally; for most, it was started within the first 24 hours of admission. On the study day, the median energy intake of the patients during the last 24 hours was 21.62 [15.9–27.3] kcal/kg and the median amount of protein intake was 1.02 [0.7–1.3] g/kg, representing 83.1% and 78.9% of the targets, respectively. A total of 64 (58.7%) patients were alive on the 28th day of the study, of them 23 (21.1% of all patients) were still in the ICU.

Conclusion

Nutrition therapy in medical ICUs was initiated early after ICU admission, the enteral route was preferred and target calories were calculated using weight-based formulas. These results suggest that multi-dimensional planning of critical care management of patients by intensivists may provide better nutritional care for the critically ill.

背景/目的营养规划是重症监护病房(ICU)护理的一个重要方面。本研究旨在评估土耳其医疗icu采用的营养做法,并调查其对现行国际准则的遵守情况。方法该多中心横断面研究在预定的研究日期进行。中心需要填写三组问卷:一组关于ICU的特征和设施,一组关于患者,一组关于患者的结果。病人的表格上有人口统计和营养状况的问题。结果共有12个站点参与研究,记录患者132例,其中109例纳入分析。中位年龄为72岁[57-83],其中55例(50%)为女性。APACHEⅱ评分中位数为23 [18-29],SOFA评分中位数为6 [4-9],BMI中位数为25.32[21.22-29.38]。超过50%的患者采用肠内喂养;对大多数人来说,这是在入院后的24小时内开始的。研究当日,患者最后24小时能量摄入中位数为21.62 [15.9-27.3]kcal/kg,蛋白质摄入中位数为1.02 [0.7-1.3]g/kg,分别达到目标的83.1%和78.9%。在研究的第28天,共有64例(58.7%)患者存活,其中23例(21.1%)仍在ICU中。结论内科重症监护室应在入院后早期开始营养治疗,优先采用肠内途径,目标热量采用体重计算公式计算。这些结果表明,重症监护医师对重症监护患者的多维规划可以为重症患者提供更好的营养护理。
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引用次数: 0
Transposition dans les unités de soin des recommandations de bonne pratique de la Haute Autorité de santé sur le diagnostic de la dénutrition de l’enfant, de l’adulte et de la personne âgée 将高级卫生当局关于诊断儿童、成人和老年人营养不良的良好做法建议纳入护理单位
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.08.001
Frédéric V. Valla , Guillaume Ulmann , Najate Achamrah , Dorothée Bedock , Véronique Douard , Evelyne Eyraud , Nicolas Flori , Vincent Fraipont , Emilie I. Guerriero , Adam Jirka , Maude Le Gall , Sébastien Le Garf , Emilie Lecoq , Caroline Martineau , Cindy Neuzillet , Aurore Pierson , Pierre Poinsot , Florian Poullenot , Thierry Quessada , Claire Rives-Lange , Christelle Guillet
<div><h3>But et objectif</h3><p>La Haute Autorité de santé et la Fédération Française de Nutrition ont publié en 2019 et 2021 de nouvelles recommandations cliniques relatives à la dénutrition chez l’enfant, l’adulte et la personne âgée. De nouvelles définitions sont ainsi proposées, basée sur une mise à jour des critères diagnostiques et de leurs valeurs seuil. Le défi est désormais la diffusion de ces recommandations et leur mise en pratique au quotidien par les professionnels de santé concernés.</p></div><div><h3>Matériel et méthodes</h3><p>Le conseil scientifique et le comité éducationnel et de pratique clinique de la société francophone de nutrition clinique et métabolisme ont appliqué à ces recommandations nouvelles la méthode Pronovost, validée comme un des outils d’aide à la transposition/implémentation des recommandations à la pratique clinique.</p></div><div><h3>Résultats</h3><p>Le modèle Pronovost a permis de proposer un cadre servant de guide à l’implémentation des recommandations sur la dénutrition dans la pratique, avec l’aide de document et d’outils adaptés. Les quatre étapes-clé de transposition clinique des recommandations sont suivies : résumer les recommandations ; identifier les freins locaux à l’implémentation ; mesurer la performance ; s’assurer que l’ensemble des patients bénéficie de ces recommandations. Des checklists pertinentes sont proposées pour l’implémentation et l’évaluation de la compliance aux recommandations, ainsi que des tableaux détaillant les missions respectives de chaque professionnel.</p></div><div><h3>Conclusion</h3><p>La méthode Pronovost fournit un cadre et des outils aux professionnels de santé, afin de faciliter la transposition des récentes recommandations du diagnostic et dépistage de la dénutrition.</p></div><div><h3>Objectives</h3><p>The French ministry of health and the French federation of nutrition published in 2019 and 2021 updated clinical recommendations around nutritional status assessment in children, adults and elderly people. New definitions of undernutrition were produced based on new criteria and/or new thresholds. The challenge now is to engage with healthcare professionals to implement these into their daily practice.</p></div><div><h3>Material and methods</h3><p>This practical implementation guide uses the established implementation model Pronovost to help implementing these evidence-based clinical recommendations into clinical practice.</p></div><div><h3>Results</h3><p>The Pronovost implementation model of evidence into practice allowed us to provide a practical framework with associated documents and tools to facilitate implementation of these clinical recommendations into healthcare professional practice. The paper is structured around the four steps of the Pronovost model: summary of the evidence; identification of local barriers to implementation; measurement of performance; ensuring all patients receive the intervention. Relevant checklists for implementation and compliance mo
2019年和2021年,高级卫生当局和法国营养联合会发布了关于儿童、成人和老年人营养不良的新临床建议。因此,根据最新的诊断标准及其阈值,提出了新的定义。现在的挑战是传播这些建议,并由有关保健专业人员在日常基础上实施这些建议。教育装备和méthodesLe科学技术咨询小组和临床实践临床营养与代谢的法语社会新方法采用了这些建议Pronovost验证过的,作为一个辅助工具调换tro /临床实践提出建议。结果Pronovost模型提出了一个框架,在适当的文件和工具的帮助下,作为在实践中实施营养不良建议的指南。遵循临床转换建议的四个关键步骤:总结建议;识别实施中的本地障碍;衡量绩效;确保所有患者都能从这些建议中受益。提出了执行和评估遵守建议情况的相关清单,以及详细说明每个专业人员各自任务的表格。结论Pronovost方法为卫生专业人员提供了一个框架和工具,以促进最近关于营养不良诊断和筛查的建议的转换。法国卫生部和法国营养联合会于2019年和2021年发表了关于儿童、成人和老年人营养状况评估的最新临床建议。根据新的标准和/或新的阈值,对营养不良作出了新的定义。现在的挑战是与保健专业人员接触,将这些措施落实到日常实践中。实际实施指南的材料和方法利用Pronovost的既定实施模式,帮助将这些循证临床建议落实到临床实践中。Pronovost实施循证实践模式的结果使我们能够提供一个具有相关文件和工具的实用框架,以促进将这些临床建议落实到医疗专业实践中。本文是根据代词模型的四个步骤构建的:证据摘要;确定实施的地方障碍;绩效测量;确保所有患者接受干预。除了列出专业人员各自职责和任务的表外,还提出了执行和遵守情况监测的相关清单。ConclusionImplementation models like the help Pronovost model)实施临床科学建议融入临床实践。
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引用次数: 0
Rôle du pharmacien d’officine dans le dépistage et l’orientation des patients atteints de troubles du comportement alimentaire 药剂师在饮食行为障碍患者筛查和指导中的作用
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.09.002
Bertrand Dufils , Marie Galmiche , Pierre Déchelotte

Eating disorders (EDs) affect around 14% of the French population, and represent a major public health issue due to their high morbidity and mortality. Insufficient and often late screening of ED leads to treatment at an advanced stage, with reduced efficacy, a prolonged course and negative medicosocial and financial consequences. Pharmacists can play a useful role in the screening and care of EDs. Indeed, patients with ED often have a high level of health care consumption due to the high frequency of their multiple symptoms and associated comorbidities, and a high propensity for self-medication, which frequently brings them to the pharmacy. The aim of this review is to highlight the role of the pharmacist in the screening for EDs and in the support of patients in the pharmacy, by proposing: key elements of semiology and pathophysiology; alerts for identifying at-risk patients; advice on language and attitude for the pharmaceutical interview in order to create a therapeutic alliance and facilitate acceptance of screening, notably with the help of validated digital tools, whether or not the patient initially requests it; advice on symptom care and orientation towards a care pathway. In this way, the dispensary pharmacist can play a very useful role in the earlier screening and support of patients with ED, as part of a multidisciplinary team providing comprehensive ED care.

饮食失调(EDs)影响了约14%的法国人口,并且由于其高发病率和死亡率而成为一个主要的公共卫生问题。ED筛查不充分且往往较晚,导致治疗进展到晚期,导致疗效降低、病程延长以及负面的医学、社会和经济后果。药师可以在急诊科的筛查和护理中发挥有益的作用。事实上,ED患者往往有很高的医疗保健消费水平,因为他们的多种症状和相关合并症的频率很高,而且他们有很高的自我药疗倾向,这经常把他们带到药房。这篇综述的目的是通过提出:符号学和病理生理学的关键要素来强调药剂师在筛查急诊科和支持患者在药房中的作用;用于识别高危患者的警报;就药物访谈的语言和态度提出建议,以便建立治疗联盟,促进接受筛查,特别是在经过验证的数字工具的帮助下,无论患者最初是否要求;关于症状护理的建议和护理途径的方向。通过这种方式,药房药剂师可以在早期筛查和支持ED患者中发挥非常有用的作用,作为提供全面ED护理的多学科团队的一部分。
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引用次数: 0
Prise en charge nutritionnelle d’une patiente âgée obèse atteinte de sclérose latérale primitive 原发性侧索硬化症老年肥胖患者的营养管理
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.09.003
Emeline Cuvilliez , Jean Claude Desport , Stéphane Meyer , Géraldine Lautrette , Carole Villemonteix , Sandra Guérin , Corentin Varrier , Aurélie Lavaud , Philippe Fayemendy , Pierre Jésus , Jean Louis Fraysse

A patient in a nursing home suffered from primary lateral sclerosis (PLS), which is a slowly progressive neuromuscular disease, in her case, very disabling. She gradually developed obesity. The possibility of an underlying sarcopenia was eliminated, and the weight gain was explained by very low physical activity and especially uncontrolled snacking. In the absence of treatment for PLS, the patient was considered to be in a palliative situation. Invoking respect for her quality of life, she refused to moderate her snacking. The only recourse was to provide dietary advice to the patient, the teams and her family. This clinical case highlights the difficulty of nutritional assessment and management of people with neurological and neuromuscular diseases.

一位在养老院的病人患有原发性侧索硬化症(PLS),这是一种缓慢进展的神经肌肉疾病,在她的情况下,非常致残。她逐渐变得肥胖。排除了潜在的肌肉减少症的可能性,体重增加的原因是体育活动很少,尤其是不受控制的零食。在没有治疗PLS,病人被认为是在姑息的情况下。为了表示对她生活质量的尊重,她拒绝减少吃零食的量。唯一的办法是向病人、医疗团队和她的家人提供饮食建议。这个临床病例突出了对神经和神经肌肉疾病患者进行营养评估和管理的困难。
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引用次数: 0
Issue contents 问题内容
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/S0985-0562(23)00273-X
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引用次数: 0
Colostrum supplement, IGF-1, and diarrhea in mechanically-ventilated patients: A double-blind, randomized, placebo-controlled study 机械通气患者初乳补充、IGF-1和腹泻:一项双盲、随机、安慰剂对照研究
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.09.004
Elham Roohelhami , Zahra Vahdat Shariatpanahi , Seyed Hossein Ardehali

Background

Diarrhea is relatively common in critically-ill mechanically-ventilated patients. This study investigated the effect of bovine colostrum supplement in the prevention of diarrhea.

Methods

Mechanically-ventilated patients expected to require enteral nutrition for at least five days were randomly assigned to the intervention or placebo groups. The intervention group received enteral diet providing 30 g of bovine colostrum daily, and the control group received a similar diet except for whey protein as a placebo. The duration of the intervention was ten days. Serum levels of IGF-1 were measured at baseline and the end of the intervention. Patients were followed up for the occurrence of diarrhea.

Results

Out of 136 participants, 45 patients in the colostrum group and 45 patients in the control group were included in the final analysis of the outcomes. Plasma IGF-1 concentration increased significantly in the colostrum group after the intervention (P = 0.02). In the between-group comparison, the increase in IGF-1 was significantly higher in the colostrum group compared with the placebo group (P = 0.04). Furthermore, the incidence of diarrhea was significantly lower in the colostrum group compared to the control group.

Conclusion

Bovine colostrum supplementation increased serum levels of IGF-1 and may reduce the incidence of diarrhea in critically-ill mechanically-ventilated patients.

背景:腹泻在危重机械通气患者中较为常见。本研究探讨了补充牛初乳对腹泻的预防作用。方法将预计需要肠内营养至少5天的机械通气患者随机分为干预组和安慰剂组。干预组接受每日提供30克牛初乳的肠内饮食,对照组接受类似的饮食,除了乳清蛋白作为安慰剂。干预的持续时间为十天。在基线和干预结束时测量血清IGF-1水平。随访患者腹泻情况。结果136例患者中,45例初乳组和45例对照组纳入最终结果分析。干预后初乳组血浆IGF-1浓度显著升高(P = 0.02)。在组间比较中,初乳组IGF-1的升高明显高于安慰剂组(P = 0.04)。此外,与对照组相比,初乳组腹泻的发生率显著降低。结论补充牛初乳可提高危重机械通气患者血清IGF-1水平,降低腹泻发生率。
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引用次数: 1
L’endoscopie bariatrique et métabolique. États des lieux et futur 减肥和代谢内窥镜检查。状态和未来
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.09.001
Maxime Thobois, Cécile Gomercic, Thierry Piche, Geoffroy Vanbiervliet

Obesity and overweight are proving to be pandemic public health problems that significantly reduce the life expectancy of those affected. Obesity has a significant medico-economic impact, in relation to the treatments it requires and its comorbidities. In France, the therapeutic management of this pathology is limited to a lifestyle modification or a surgical approach. Endoscopy has allowed the development of therapeutic alternatives in the management of obesity in recent years, although not all of these methods are currently recommended in France, even though convincing results have been shown. With the advent of organ-sparing interventional endoscopy, innovative minimally invasive therapeutic procedures have emerged and will tend to develop in order to take a full place in the treatment of this chronic disease. More ambitious endoscopic procedures could also be combined, thus combining the different modes of action of each of them. Finally, with the availability of new effective drug treatments, combined “endoscopy-drug” approaches could be newly defined to achieve unprecedented clinical effectiveness. The objective of this review will be to present the current endoscopic techniques available for the management of obesity, to discuss the innovative procedures under development and to outline the future of bariatric endoscopy, either by combining procedures or by combining them with medical therapies.

肥胖和超重已被证明是大流行的公共卫生问题,会大大缩短受影响者的预期寿命。就其所需的治疗及其合并症而言,肥胖具有重大的医学经济影响。在法国,这种病理的治疗管理仅限于生活方式的改变或手术方法。近年来,内窥镜检查使肥胖症治疗方案的发展成为可能,尽管目前在法国并非所有这些方法都被推荐,尽管已经显示出令人信服的结果。随着保留器官的介入内窥镜的出现,创新的微创治疗方法已经出现,并将趋于发展,以便在这种慢性疾病的治疗中占据完全的位置。更雄心勃勃的内窥镜手术也可以结合起来,从而结合它们各自不同的作用模式。最后,随着新的有效药物治疗方法的出现,可以重新定义“内镜-药物”联合方法,以获得前所未有的临床效果。本综述的目的是介绍目前可用于肥胖治疗的内窥镜技术,讨论正在开发的创新程序,并概述减肥内窥镜的未来,无论是结合程序还是与药物治疗相结合。
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引用次数: 0
L’éditorial de la présidente de la SFNCM SFNCM主席的社论
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.11.001
Francisca Joly
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引用次数: 0
Oral iron powder for prehabilitation in hip and knee arthroplasty: A randomized controlled trial to optimize hemoglobin concentration 口服铁粉用于髋关节和膝关节置换术中的康复:优化血红蛋白浓度的随机对照试验
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-11-01 DOI: 10.1016/j.nupar.2023.08.002
Matteo Briguglio , Tiziano Crespi , Marco Mazzocchi , Stefano Petrillo , Cristina Turco , Elena De Vecchi , Patrizia Riso , Marisa Porrini , Giuseppe Banfi , Sergio Romagnoli , Paolo Perazzo

Background

One of the key aspects to enhance the suitability for surgery in elective arthroplasty is the optimization of hemoglobin concentration. In this randomized controlled trial, we investigated the efficacy of an oral iron supplement and its impact on blood management practices.

Materials and methods

A total of 60 older adults undergoing elective hip or knee surgery were randomized to follow a month and a half of supplementation with a water-soluble powder containing iron and vitamins. We monitored iron homeostasis and the use of blood resources.

Results

The trial was completed by 58 subjects. We observed a significant inter-group change in hemoglobin and its mean corpuscular concentration (P < 0.05), vitamin B6, B9 (P < 0.001), and B12 (P < 0.05). Albeit not statistically significant, fewer patients in the intervention group had hemoglobin over the threshold for blood unit request before (11 vs. 14) or transfusion evaluation after surgery (1 vs. 6), or actually received a blood transfusion (1 vs. 3). The extent of preoperative iron deficiency and hematocrit were predictive for postoperative blood units (AUC = 0.9).

Conclusion

Iron homeostasis improved in the intervention group, while the changes in the control group were consistent with the depletion of iron reserves. The iron-based formulation enriched with vitamins was safe but showed a slight impact on blood management practices. The potential of optimizing patient blood management encourages the planning of large-scale studies, possibly combining a diet therapy to promote the consumption of foods rich in iron long before the operation.

背景:提高选择性关节置换术手术适宜性的关键因素之一是优化血红蛋白浓度。在这个随机对照试验中,我们调查了口服铁补充剂的功效及其对血液管理实践的影响。材料和方法共60名接受择期髋关节或膝关节手术的老年人被随机分组,接受为期一个半月的含铁和维生素的水溶性粉末补充剂。我们监测铁稳态和血液资源的使用。结果共完成试验58例。我们观察到血红蛋白及其平均红细胞浓度在组间有显著变化(P <0.05),维生素B6, B9 (P <0.001), B12 (P <0.05)。虽然没有统计学意义,但干预组患者血红蛋白在术前(11比14)或术后输血评估(1比6)或实际接受输血(1比3)前超过血单位要求阈值的患者较少(1比6)。术前缺铁和红细胞压积的程度可预测术后血单位(AUC = 0.9)。结论干预组铁稳态改善,而对照组的改变与铁储备的耗竭一致。富含维生素的铁基配方是安全的,但对血液管理实践的影响很小。优化患者血液管理的潜力鼓励了大规模研究的规划,可能结合饮食疗法,在手术前很久就促进富含铁的食物的摄入。
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引用次数: 0
Épidémiologie de la nutrition parentérale à domicile chez l’adulte en France 法国成人家庭肠外营养流行病学
IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.nupar.2023.05.004
Dominique Lescut , Nicolas Danel Buhl , Luc Dauchet , Marie-France Vaillant , Stéphane Schneider

Objective

French epidemiological data regarding home parenteral nutrition (HPN) are not well known and give rise to imprecise estimates. This study targets the adult population to obtain accurate data especially by trying to determine the pathologies associated with the HPN.

Methods

A retrospective and observational study covering the year 2017 (from 01/01 to 31/12/2017) has been carried out, with the data of the adult population aged over 15 years, by defining three age groups: 15–39 years, 40–64 years, 65 years and over. The databases of the health insurance allowed to obtain on the one hand, the number of patients who started HPN and on the other hand, the number of patients followed in HPN. The target population (health insurance beneficiary population) being known, these data allowed to calculate incidence and prevalence, respectively. The data were also crossed with the thirty long-term diseases file of health national insurance (ALD 30), allowing patients to be classified into six categories: cancer, neurology, chronic intestinal inflammatory diseases, organ deficiency, others pathologies, and undetermined pathologies.

Results

Data from 92.1% of adult national population were obtained, totaling 50.8 millions adults. The average incidence and prevalence of HPN were estimated at 20.8/100,000 inhabitants/yr and 26.0/100,000 inhabitants, respectively. Prevalence of long-term HPN (> 12 weeks) was 6.0/100,000 inhabitants. The main pathology was cancer. Inflammatory bowel diseases were the second cause of HPN in the age range 15–39 years.

Conclusion

This is the first national study on the epidemiology of HPN in adults in France, based on data from health insurance. The projection of these figures to the entire French adult population leads to an estimate of around 14,300 patients per year benefiting from national health insurance for HPN, mainly for cancer diseases.

目的法国关于家庭肠外营养(HPN)的流行病学数据不为人所知,并导致不精确的估计。本研究针对成年人群,特别是通过尝试确定与HPN相关的病理来获得准确的数据。方法对2017年(2017年1月1日至12月31日)的15岁以上成年人群的数据进行了回顾性和观察性研究,定义了三个年龄组:15-39岁、40-64岁、65岁及以上。健康保险数据库一方面可以获得开始HPN的患者人数,另一方面可以获取HPN随访的患者人数。目标人群(健康保险受益人群)是已知的,这些数据可以分别计算发病率和患病率。数据还与健康国家保险(ALD 30)的30种长期疾病档案交叉,将患者分为六类:癌症、神经病学、慢性肠道炎症性疾病、器官缺乏、其他病理学和未确定病理学。结果获得的数据来自全国92.1%的成年人口,共计5080万成年人。HPN的平均发病率和患病率估计分别为20.8/10万居民/年和26./10万居民。长期HPN(>12周)的患病率为6.0/10万居民。主要病理为癌症。炎症性肠病是15-39岁人群中HPN的第二大病因。结论这是法国首次基于健康保险数据对成人HPN流行病学进行全国性研究。根据这些数字对整个法国成年人口的预测,估计每年约有14300名患者受益于HPN国家医疗保险,主要是癌症疾病。
{"title":"Épidémiologie de la nutrition parentérale à domicile chez l’adulte en France","authors":"Dominique Lescut ,&nbsp;Nicolas Danel Buhl ,&nbsp;Luc Dauchet ,&nbsp;Marie-France Vaillant ,&nbsp;Stéphane Schneider","doi":"10.1016/j.nupar.2023.05.004","DOIUrl":"https://doi.org/10.1016/j.nupar.2023.05.004","url":null,"abstract":"<div><h3>Objective</h3><p>French epidemiological data regarding home parenteral nutrition (HPN) are not well known and give rise to imprecise estimates. This study targets the adult population to obtain accurate data especially by trying to determine the pathologies associated with the HPN.</p></div><div><h3>Methods</h3><p>A retrospective and observational study covering the year 2017 (from 01/01 to 31/12/2017) has been carried out, with the data of the adult population aged over 15 years, by defining three age groups: 15–39 years, 40–64 years, 65 years and over. The databases of the health insurance allowed to obtain on the one hand, the number of patients who started HPN and on the other hand, the number of patients followed in HPN. The target population (health insurance beneficiary population) being known, these data allowed to calculate incidence and prevalence, respectively. The data were also crossed with the thirty long-term diseases file of health national insurance (ALD 30), allowing patients to be classified into six categories: cancer, neurology, chronic intestinal inflammatory diseases, organ deficiency, others pathologies, and undetermined pathologies.</p></div><div><h3>Results</h3><p>Data from 92.1% of adult national population were obtained, totaling 50.8 millions adults. The average incidence and prevalence of HPN were estimated at 20.8/100,000 inhabitants/yr and 26.0/100,000 inhabitants, respectively. Prevalence of long-term HPN (&gt;<!--> <!-->12 weeks) was 6.0/100,000 inhabitants. The main pathology was cancer. Inflammatory bowel diseases were the second cause of HPN in the age range 15–39 years.</p></div><div><h3>Conclusion</h3><p>This is the first national study on the epidemiology of HPN in adults in France, based on data from health insurance. The projection of these figures to the entire French adult population leads to an estimate of around 14,300 patients per year benefiting from national health insurance for HPN, mainly for cancer diseases.</p></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"37 3","pages":"Pages 149-154"},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49841981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Nutrition Clinique et Metabolisme
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