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MXene electrochemical phosphate sensors. MXene电化学磷酸盐传感器。
Pub Date : 2025-11-12 DOI: 10.1038/s44172-025-00519-x
Thiba Nagaraja, Anupma Thakur, Andrey Krayev, A Edward Robinson, Aleksandra Vojvodic, Babak Anasori, Suprem R Das

Rapid and accurate detection of molecular species with a high degree of selectivity and sensitivity constitutes the ultimate goal of designing sensors for various applications, from studying nutrients in soil-water systems to assessing physiological conditions in human health. With recent progress, two-dimensional (2D) transition metal carbides/nitrides have shown great potential for applications such as energy storage and electromagnetic interference shielding. However, the fundamental electrochemical studies and subsequent applications of MXenes for molecular sensing are still in their infancy. Here, we use 2D sheets of titanium carbide (Ti3C2Tx) MXene for electrochemical detection of phosphate, a key molecule for sustainability of life on earth, and major contributor to environmental pollution. Ti3C2Tx MXene sensors were demonstrated to be highly selective towards phosphate with a sensing range from 1 µM to 350 µM and a limit of detection (LOD) of 1.31 µM. This work lays the foundation for molecular sensing using Ti3C2Tx MXene in complex environments.

从研究土壤-水系统中的营养物质到评估人类健康的生理状况,快速、准确地检测具有高度选择性和灵敏度的分子物种构成了设计各种应用传感器的最终目标。随着近年来的进展,二维(2D)过渡金属碳化物/氮化物在储能和电磁干扰屏蔽等方面显示出巨大的应用潜力。然而,MXenes在分子传感方面的基础电化学研究和后续应用仍处于起步阶段。在这里,我们使用二维碳化钛(Ti3C2Tx) MXene薄片对磷酸盐进行电化学检测,磷酸盐是地球上生命可持续发展的关键分子,也是环境污染的主要贡献者。Ti3C2Tx MXene传感器对磷酸盐具有高度选择性,传感范围为1µM至350µM,检测限(LOD)为1.31µM。这项工作为在复杂环境中使用Ti3C2Tx MXene进行分子传感奠定了基础。
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引用次数: 0
Continuous tuning of ejector parameters via zeotropic component migration for optimising high-temperature heat pump. 通过共沸组分迁移对喷射器参数进行连续调整以优化高温热泵。
Pub Date : 2025-11-12 DOI: 10.1038/s44172-025-00518-y
Zhengyong Li, Youcai Liang, Yan Zhu, Shunchun Yao, Zhibin Yu

As the temperature lift increases, heat pump performance declines due to rising throttling losses in expansion valves. Ejectors present a promising alternative, enabling power recovery from the throttling process. However, fixed-geometry ejectors suffer performance degradation under off-design conditions. Here we propose leveraging the component migration characteristics of zeotropic refrigerants to continuously adjust critical ejector parameters by modulating the quality. This approach enables optimal performance across varying conditions without mechanical modifications. A vapor-injection heat pump cycle incorporating a component-adjustable ejector with three tunable parameters is developed. The concept of equivalent ejector efficiency was introduced, and the adjustment capability of typical high-temperature refrigerant mixtures was investigated, such as mixtures of butane (R600) and synthetic refrigerants (R245fa). Results show that, at a nominal heating capacity of 100 kW, R600/R245fa achieves a lower adjustable limit of -5%, compared to -2% for R1224yd(Z)/R1233zd(E) (synthetic refrigerant mixtures). These findings demonstrate the feasibility of efficient operation of fixed-geometry ejectors under variable conditions. The proposed system and regulation strategy offer a promising design alternative for industrial high-temperature heat pump applications.

随着温度提升的增加,由于膨胀阀节流损失的增加,热泵性能下降。喷射器是一种很有前途的替代方案,可以从节流过程中回收功率。然而,在非设计条件下,固定几何喷射器的性能会下降。在此,我们建议利用共沸制冷剂的组分迁移特性,通过调节质量来连续调整关键喷射器参数。这种方法可以在不同的条件下实现最佳性能,而无需进行机械修改。研制了一种具有三个可调参数的组件可调喷射器的蒸汽喷射热泵循环。引入了等效喷射器效率的概念,研究了丁烷(R600)与合成制冷剂(R245fa)混合等典型高温制冷剂的调节能力。结果表明,在100kw的标称供热能力下,R600/R245fa的可调限值为-5%,而R1224yd(Z)/R1233zd(E)(合成制冷剂混合物)的可调限值为-2%。这些发现证明了固定几何喷射器在可变条件下高效工作的可行性。所提出的系统和调节策略为工业高温热泵应用提供了一个有前途的设计方案。
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引用次数: 0
Enabling multirotor UAVs to perch, land and detach with standard propeller guards. 使多旋翼无人机能够停泊,着陆和分离与标准螺旋桨保护。
Pub Date : 2025-11-11 DOI: 10.1038/s44172-025-00514-2
Yuying Zou, Haotian Li, Yunfan Ren, Fanze Kong, Wei Xu, Yihang Li, Yixi Cai, Fu Zhang

The widespread adoption of multirotor uncrewed aerial vehicles (UAVs) is hindered by limited flight time and degraded stability to wind disturbances. Perching, inspired by birds, offers a solution by saving energy and maintaining stability. However, current perching methods often rely on heavy mechanisms, have limitations on surface materials, and obstruct vision sensors. In this study, we propose a process to enable multirotors to perch, land, and detach, all with standard propeller guards. This approach eliminates additional mechanisms, avoids sensor interference, and significantly reduces energy consumption by leveraging the ceiling effect. In over 150 perching and detaching tests with various surface orientations and materials, the approach achieved a 100% success rate and saved 25% - 100% energy consumption compared to hovering. It also improved positioning accuracy by 50 times under strong winds by ensuring stable environmental contact. We demonstrated in real-world environments, showcasing the autonomous perching and detaching ability using only onboard sensing and computation.

多旋翼无人飞行器(uav)的广泛采用受到飞行时间有限和对风扰动稳定性下降的阻碍。栖息的灵感来自鸟类,提供了一种既节约能源又保持稳定的解决方案。然而,目前的栖息方法往往依赖于重型机械,对表面材料有限制,并且阻碍视觉传感器。在这项研究中,我们提出了一个过程,使多旋翼悬停,着陆和分离,所有与标准螺旋桨保护。这种方法消除了额外的机制,避免了传感器干扰,并通过利用天花板效应显著降低了能耗。在150多次不同表面取向和材料的悬停和分离测试中,该方法取得了100%的成功率,与悬停相比节省了25% - 100%的能耗。它还通过确保稳定的环境接触,将强风下的定位精度提高了50倍。我们在现实环境中进行了演示,展示了仅使用车载传感和计算的自主停泊和分离能力。
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引用次数: 0
Adaptive continuous-shape-changing solar-powered microfliers enabled by a drone-mounted releasing module. 自适应连续形状变化的太阳能微型飞行器由无人机安装的释放模块实现。
Pub Date : 2025-11-11 DOI: 10.1038/s44172-025-00516-0
Haoyang Sun, Chenxi Yang, Zhenlong Wang, Yifan Wang, Xinrui Zhang, Yunhao Ren, Wenhua Li, Honglong Chang, Kan Li, YongAn Huang, Binghe Ma, Weizheng Yuan, Tao Ye

The exceptional adaptability of biological organisms to new environments is difficult to replicate in artificial robots. Although dandelion-inspired microfliers have successfully mimicked passive wind dispersal of dandelion seeds with long travel distances and certain controllable landing capacities, existing designs have yet to replicate the adaptive abscission and continuous-shape-changing mechanisms observed in species. Here we propose a programmable adaptive continuous-shape-changing solar-powered microflier enabled by a drone-mounted releasing module and actuated by the shape memory alloy actuators with a minimal total weight of 198 mg. The designed microfliers synergistically mimic the adaptive abscission and continuous-shape-changing mechanisms of dandelion seeds, enabling swarm adjustments of aerodynamics and flight performances in response to multi-environmental factors. Moreover, our microfliers demonstrate controlled interval deployments, programmable flight performances, and robust self-sustaining operations, facilitating their level of intelligence and practical applications.

生物有机体对新环境的特殊适应性很难在人工机器人中复制。虽然受蒲公英启发的微型飞行器已经成功地模仿了蒲公英种子的被动风传播,具有长距离的传播距离和一定的可控着陆能力,但现有的设计尚未复制在物种中观察到的适应性脱落和连续形状变化机制。本文提出了一种可编程自适应连续变形太阳能微型飞行器,该飞行器由安装在无人机上的释放模块驱动,由形状记忆合金致动器驱动,总重量最小为198 mg。设计的微型飞行器协同模拟蒲公英种子的自适应脱落和连续形状变化机制,使蜂群能够根据多种环境因素调整空气动力学和飞行性能。此外,我们的微型飞行器展示了可控制的间隔部署、可编程的飞行性能和强大的自我维持操作,提高了它们的智能水平和实际应用。
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引用次数: 0
MechRAG: a multimodal large language model for mechanical engineering. 机械工程的多模态大语言模型。
Pub Date : 2025-11-11 DOI: 10.1038/s44172-025-00517-z
Shuang Li, Jonathan Corney

Engineering design and manufacture are inherently multimodal activities in which engineers consult and produce diverse data and representations across various engineering disciplines and product lifecycle stages. Although well-established digital formats exist for these representations, their use remains restricted within specialist applications, creating silos that limit cross-domain integration. Here we introduce mechanical retrieval-augmented generation (MechRAG), a multimodal large language model architecture designed to unify information from multiple engineering representations typically found in computer-aided engineering and computer-aided design environments. Results demonstrate that MechRAG achieves high accuracy in routinely performed mechanical activities such as data-management or classification tasks, and effectively replicates engineer-level reasoning in more inferential and subjective contexts. Our findings suggest that such conversational interfaces enhance engineering productivity, facilitate more interactive paradigms, and drive transformative workflows across various stages of design and manufacturing.

工程设计和制造本质上是多模式活动,工程师在不同的工程学科和产品生命周期阶段咨询和产生不同的数据和表示。尽管这些表示存在完善的数字格式,但它们的使用仍然限制在专业应用程序中,从而产生了限制跨域集成的筒仓。在这里,我们介绍机械检索增强生成(MechRAG),这是一种多模态大语言模型体系结构,旨在统一来自计算机辅助工程和计算机辅助设计环境中常见的多种工程表示的信息。结果表明,MechRAG在数据管理或分类任务等常规机械活动中达到了很高的准确性,并在更多的推理和主观环境中有效地复制了工程师级别的推理。我们的研究结果表明,这种对话界面提高了工程生产力,促进了更多的交互范例,并推动了设计和制造各个阶段的变革工作流程。
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引用次数: 0
StarWhisper Telescope: an AI framework for automating end-to-end astronomical observations. StarWhisper望远镜:一个自动化端到端天文观测的人工智能框架。
Pub Date : 2025-11-06 DOI: 10.1038/s44172-025-00520-4
Cunshi Wang, Yu Zhang, Yuyang Li, Xinjie Hu, Yiming Mao, Xunhao Chen, Pengliang Du, Rui Wang, Ying Wu, Hang Yang, Yansong Li, Beichuan Wang, Haiyang Mu, Xiaohan Chen, Shunxuan He, Hao Mo, Liyue Zhang, Lin Du, Yunning Zhao, Jianfeng Tian, Liang Ge, Yongna Mao, Shengming Li, Zheng Wang, Xiaomeng Lu, Jinhang Zou, Yang Huang, Ningchen Sun, Jie Zheng, Min He, Yu Bai, Junjie Jin, Hong Wu, Jifeng Liu

The exponential growth of large-scale telescope arrays has boosted time-domain astronomy development but introduced operational bottlenecks, including labor-intensive observation planning, data processing, and real-time decision-making. Here we present the StarWhisper Telescope system, an AI agent framework automating end-to-end astronomical observations for surveys like the Nearby Galaxy Supernovae Survey. By integrating large language models with specialized function calls and modular workflows, StarWhisper Telescope autonomously generates site-specific observation lists, executes real-time image analysis via pipelines, and dynamically triggers follow-up proposals upon transient detection. The system reduces human intervention through automated observation planning, telescope controlling and data processing, while enabling seamless collaboration between amateur and professional astronomers. Deployed across Nearby Galaxy Supernovae Survey's network of 10 amateur telescopes, StarWhisper Telescope has detected transients with promising response times relative to existing surveys. Furthermore, StarWhisper Telescope's scalable agent architecture provides a blueprint for future facilities like the Global Open Transient Telescope Array, where AI-driven autonomy will be critical for managing 60 telescopes.

大规模望远镜阵列的指数级增长促进了时域天文学的发展,但也带来了操作瓶颈,包括劳动密集型的观测计划、数据处理和实时决策。在这里,我们展示了StarWhisper望远镜系统,这是一个人工智能代理框架,可以自动进行端到端的天文观测,例如近星系超新星调查。通过将大型语言模型与专门的函数调用和模块化工作流程相结合,StarWhisper望远镜可以自主生成特定地点的观测列表,通过管道执行实时图像分析,并在瞬态检测时动态触发后续建议。该系统通过自动观测规划、望远镜控制和数据处理减少了人为干预,同时实现了业余和专业天文学家之间的无缝协作。部署在邻近星系超新星调查的10个业余望远镜网络上,StarWhisper望远镜已经探测到与现有调查相比有希望响应时间的瞬变。此外,StarWhisper望远镜的可扩展代理架构为全球开放瞬态望远镜阵列等未来设施提供了蓝图,其中人工智能驱动的自主性将对管理60台望远镜至关重要。
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引用次数: 0
Perpendicular-anisotropy artificial spin ice with spontaneous ordering: a platform for reservoir computing with flexible timescales. 具有自发有序的垂直各向异性人工自旋冰:具有柔性时间尺度的油藏计算平台。
Pub Date : 2025-11-03 DOI: 10.1038/s44172-025-00499-y
Aleksandr Kurenkov, Jonathan Maes, Aleksandra Pac, Gavin Martin Macauley, Bartel Van Waeyenberge, Aleš Hrabec, Laura Jane Heyderman

Arrays of coupled nanomagnets have wide-ranging fundamental and practical applications in artificial spin ices, reservoir computing and spintronics. However, lacking in these fields are nanomagnets with perpendicular magnetic anisotropy with sufficient magnetostatic interaction. This would not only open up unexplored possibilities for artificial spin ice geometries but also enable novel coupling methods for applications. Here, we demonstrate a method to engineer the energy landscape of artificial spin lattices with perpendicular magnetic anisotropy. With this, we are able to realize for the first time strongly magnetostatically-coupled 2D lattices of out-of-plane Ising spins that spontaneously order at room temperature on timescales that can be precisely engineered. We show how this property, together with straightforward electrical interfacing, make this system a promising platform for reservoir computing. Our results open the way to investigate the thermodynamics of out-of-plane magnetostatically coupled nanomagnet arrays with novel spin ice geometries, as well as to exploit such nanomagnet arrays in unconventional computing, taking advantage of the adjustable temporal dynamics and strong coupling between nanomagnets.

耦合纳米磁体阵列在人工自旋冰、储层计算和自旋电子学中有着广泛的基础和实际应用。然而,在这些磁场中缺乏具有垂直磁各向异性和足够的静磁相互作用的纳米磁体。这不仅为人工自旋冰的几何形状开辟了未知的可能性,而且还为应用提供了新的耦合方法。在这里,我们展示了一种方法来设计具有垂直磁各向异性的人工自旋晶格的能量景观。有了这个,我们能够首次实现平面外伊辛自旋的强静磁耦合二维晶格,这些晶格在室温下可以在精确设计的时间尺度上自发有序。我们展示了这种特性以及简单的电气接口如何使该系统成为储层计算的一个有前途的平台。我们的研究结果为研究具有新型自旋冰几何形状的面外静磁耦合纳米磁体阵列的热力学开辟了道路,并利用纳米磁体之间可调节的时间动力学和强耦合的优势,将这种纳米磁体阵列应用于非常规计算。
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引用次数: 0
Benchmarking scientific machine-learning approaches for flow prediction around complex geometries. 围绕复杂几何形状进行流量预测的基准科学机器学习方法。
Pub Date : 2025-10-31 DOI: 10.1038/s44172-025-00513-3
Ali Rabeh, Ethan Herron, Aditya Balu, Soumik Sarkar, Chinmay Hegde, Adarsh Krishnamurthy, Baskar Ganapathysubramanian

Rapid and accurate simulations of fluid dynamics around complicated geometric bodies are critical in a variety of engineering and scientific applications. While scientific machine learning (SciML) has shown considerable promise, most studies in this field are limited to simple geometries. This paper addresses this gap by benchmarking diverse SciML models, including neural operators and vision transformer-based foundation models, for fluid flow prediction over intricate geometries. We evaluate the impact of geometric representations-Signed Distance Fields (SDF) and binary masks-on model accuracy, scalability, and generalization using a high-fidelity dataset of steady-state flow over complex geometries. We introduce a unified scoring framework that integrates metrics for global accuracy, boundary layer fidelity, and physical consistency. Our findings reveal that newer foundation models significantly outperform neural operators, particularly in data-limited scenarios. In addition, binary mask representation enhances the performance of vision transformer models by up to 10%, while SDF representations improve neural operator performance by up to 7%. Despite these promises, all models struggle with out-of-distribution generalization, highlighting a critical challenge for future SciML applications. Our work paves the way for robust and scalable ML solutions for fluid dynamics across complex geometries.

在各种工程和科学应用中,快速准确地模拟复杂几何物体周围的流体动力学是至关重要的。虽然科学机器学习(SciML)已经显示出相当大的前景,但该领域的大多数研究仅限于简单的几何形状。本文通过对各种SciML模型(包括神经算子和基于视觉变换的基础模型)进行基准测试,解决了这一差距,用于复杂几何形状的流体流动预测。我们评估几何表示-符号距离场(SDF)和二进制掩码-对模型精度,可扩展性和泛化的影响,使用高保真数据集的稳态流在复杂的几何形状。我们引入了一个统一的评分框架,它集成了全局精度、边界层保真度和物理一致性的指标。我们的研究结果表明,新的基础模型明显优于神经算子,特别是在数据有限的情况下。此外,二值掩模表示将视觉变换模型的性能提高了10%,而SDF表示将神经算子的性能提高了7%。尽管有这些承诺,所有的模型都在与分布外泛化作斗争,这突出了未来SciML应用的一个关键挑战。我们的工作为复杂几何形状流体动力学的强大和可扩展的ML解决方案铺平了道路。
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引用次数: 0
Evolution mechanism and progressive reshaping model of driving behaviors when humans take over intelligent vehicles. 人类接管智能汽车时驾驶行为的进化机制与渐进重塑模型
Pub Date : 2025-10-31 DOI: 10.1038/s44172-025-00510-6
Ziyu Zhang, Chunyan Wang, Zhongkai Luan, Wanzhong Zhao

Despite the rapid development of autonomous driving, drivers still need to take over when autonomous driving exceeds its design scope or malfunctions. The role of drivers is undergoing a significant transformation from operators to backup users. The existing human driving behaviour models focus more on the behaviour of humans as operators, with static and time-invariant characteristics. However, as backup users, human behaviour characteristics during the takeover process exhibit dynamic and time-varying characteristics, and traditional driver models can no longer describe these, making it difficult to support the safe development of autonomous driving. Unfortunately, the evolution mechanism of driver behaviour is unclear, which has led to the continuous occurrence of accidents in autonomous vehicles. To support the safe development of autonomous driving, we studied the changes in drivers' cognition, decision-making, and control behaviours during the takeover, revealing the evolution mechanism of driver behaviours during the takeover. On this basis, a progressive reshaping model of human driving behaviours is constructed. The comparison with actual driver control data shows that the accuracy of the proposed model is 88.57%, providing a new perspective for understanding driver behaviour during emergency takeover and having certain application value in the research of autonomous driving technology.

尽管自动驾驶发展迅速,但当自动驾驶超出其设计范围或出现故障时,仍然需要驾驶员接管。司机的角色正在经历从运营商到备用用户的重大转变。现有的人类驾驶行为模型更多地关注人类作为操作员的行为,具有静态和时不变的特征。然而,作为备用用户,人类在接管过程中的行为特征表现出动态和时变的特征,传统的驾驶员模型无法描述这些特征,难以支持自动驾驶的安全发展。不幸的是,驾驶员行为的进化机制尚不清楚,这导致了自动驾驶汽车事故的不断发生。为了支持自动驾驶的安全发展,我们研究了接管过程中驾驶员认知、决策和控制行为的变化,揭示了接管过程中驾驶员行为的演化机制。在此基础上,构建了人类驾驶行为的渐进重塑模型。与实际驾驶员控制数据的对比表明,所提模型的准确率为88.57%,为理解驾驶员紧急接管行为提供了新的视角,在自动驾驶技术的研究中具有一定的应用价值。
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引用次数: 0
Toward an ion-based large-scale integrated circuit: design, simulation, and integration. 迈向离子基大规模集成电路:设计、模拟与集成。
Pub Date : 2025-10-22 DOI: 10.1038/s44172-025-00511-5
Noa Edri Fraiman, Barak Sabbagh, Gilad Yossifon, Alexander Fish

Iontronics combines ions as information carriers with electronic-like operations, enabling the creation of ion-based integrated circuits that offer unique signal processing, chemical regulation, and enhanced bio-integrability. Existing simulation tools encounter difficulties in effectively modeling integrated iontronic components, highlighting the need for specialized design and simulation methodologies. Here we present a design approach toward ion-based large-scale integrated circuits, inspired by electronic integrated circuit abstraction levels. We develop a compact model for the iontronic bipolar diode, with a conceptual framework applicable to other iontronic components. The model is implemented using standard Electronic Design Automation tools, allowing simulation of static and dynamic properties of iontronic circuits. Simulated results match measurements from fabricated small-scale iontronic circuits. The proposed simulation approach employs Monte Carlo methodology and enables exploration of how component non-uniformity influences circuit behavior. We demonstrate the model's utility by simulating ion-based integrated circuits, including an iontronic decoder and diode bridge. Expanding traditional circuit design tools to support iontronics could advance the development of hybrid systems that leverage both electronic and ionic functionalities.

离子电子学将离子作为信息载体与电子类操作相结合,使离子基集成电路能够提供独特的信号处理、化学调节和增强的生物可集成性。现有的仿真工具在有效地建模集成电子元件方面遇到困难,突出了对专门设计和仿真方法的需求。在这里,我们提出了一种基于离子的大规模集成电路的设计方法,灵感来自于电子集成电路的抽象层次。我们为离子电子双极二极管开发了一个紧凑的模型,其概念框架适用于其他离子电子元件。该模型使用标准的电子设计自动化工具实现,允许模拟电子电路的静态和动态特性。模拟结果与制造的小型离子电路的测量结果相匹配。所提出的仿真方法采用蒙特卡罗方法,并能够探索元件不均匀性如何影响电路行为。我们通过模拟离子基集成电路(包括离子电子解码器和二极管桥)来证明该模型的实用性。扩展传统电路设计工具以支持电子电子学可以促进利用电子和离子功能的混合系统的发展。
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引用次数: 0
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