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Field-effect detected magnetic resonance of nitrogen-vacancy centers in diamond based on all-carbon Schottky contacts. 基于全碳肖特基触点的场效应检测了金刚石中氮空位中心的磁共振。
Pub Date : 2025-12-02 DOI: 10.1038/s44172-025-00541-z
Xuan Phuc Le, Ludovic Mayer, Simone Magaletti, Martin Schmidt, Jean-François Roch, Thierry Debuisschert

The nitrogen-vacancy (NV) center is a defect in diamond whose spin state can be read optically by exploiting its photoluminescence or electrically by exploiting its charge generation rate under illumination, both of which being spin-dependent. The latter method offers numerous opportunities in terms of integration and performance compared to conventional optical readout. Here, we investigate the physical properties of a graphitic-diamond-graphitic structure under illumination. We show how, for a type IIa diamond material, electron-hole pairs generated by an ensemble of NV centers lead to a p-type material upon illumination, making this all-carbon structure equivalent to two back-to-back Schottky diodes. We analyze how the reverse current flowing upon illumination changes as a function of bias voltage and radiofrequency-induced excitation of the NV ensemble spin resonances. Furthermore, we demonstrate how an additional field effect arising from the illumination scheme affects the reverse current, resulting in a photoelectrical signal that can exceed the optical signal under the same illumination conditions.

氮空位(NV)中心是金刚石中的一个缺陷,其自旋状态可以利用其光致发光进行光学读取,也可以利用其在光照下的电荷产生速率进行电学读取,两者都与自旋有关。与传统的光学读出相比,后一种方法在集成和性能方面提供了许多机会。在这里,我们研究了在光照下石墨-金刚石-石墨结构的物理性质。我们展示了,对于IIa型金刚石材料,由NV中心集合产生的电子-空穴对如何在照明下导致p型材料,使这种全碳结构相当于两个背靠背的肖特基二极管。我们分析了照射后的反向电流随偏置电压和NV系综自旋共振的射频激发的变化情况。此外,我们还演示了由照明方案产生的附加场效应如何影响反向电流,从而导致在相同照明条件下光电信号可以超过光信号。
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引用次数: 0
Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model. 临床磁颗粒成像:人体尸体模型中医用植入物的安全性测量。
Pub Date : 2025-12-01 DOI: 10.1038/s44172-025-00561-9
Franz Wegner, Thomas Friedrich, Patrick Naoki Elfers, Florian Kleefeldt, Dominik Peter, Philipp Gruschwitz, Teresa Reichl, Johanna Günther, Thomas Kampf, Martin A Rückert, Volker C Behr, Thorsten M Buzug, Roman Kloeckner, Jörg Barkhausen, Thorsten A Bley, Patrick Vogel, Viktor Hartung

Magnetic Particle Imaging (MPI) is a preclinical imaging modality with potential for future clinical usage. The radiation-free guidance of endovascular interventions with MPI is especially promising. Here, we present a safety study on the heating of metallic medical implants during MPI measurements under realistic conditions in an extracorporeally-perfused cadaver model. The measurements were conducted by fiberoptic thermometers and showed no detectable heating of the tested endovascular devices in the cadaver model. A temperature increase of no more than 0.11 K was observed on the surface of the investigated proximal femoral nail. The in vitro testing of orthopedic prostheses (knee and hip) revealed a slight heating effect of 0.45 K. The dependence of heating on the applied excitation frequency was measured. Overall, the tested repertoire of implants did not heat by a clinically-relevant amount in a human-sized MPI-scanner under realistic conditions, indicating their safe usage in future clinical applications.

磁颗粒成像(MPI)是一种具有临床应用潜力的临床前成像技术。利用MPI进行血管内介入治疗的无辐射指导尤其有前景。在此,我们提出了一项在体外灌注尸体模型的现实条件下,在MPI测量期间金属医学植入物加热的安全性研究。测量是通过光纤温度计进行的,在尸体模型中没有检测到被测血管内装置的加热。观察到所研究的股骨近端钉表面温度升高不超过0.11 K。骨科假体(膝关节和髋关节)的体外测试显示轻微的加热效应为0.45 K。测量了加热与外加激励频率的关系。总的来说,在现实条件下,在人体大小的mpi扫描仪中,所测试的植入物没有被临床相关的量加热,这表明它们在未来的临床应用中是安全的。
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引用次数: 0
OpenDosimeter: Open hardware personal X-ray dosimeter. OpenDosimeter:开放式硬件个人x射线剂量计。
Pub Date : 2025-12-01 DOI: 10.1038/s44172-025-00540-0
Norah Ger, Alice Ku, Jasmyn Lopez, N Robert Bennett, Jia Wang, Grace Ateka, Enoch Anyenda, Matthias Rosezky, Pamela Kilavi, Adam S Wang, Kian Shaker

Radiation workers need accurate monitoring of X-ray exposure, but existing solutions are either inaccessible, expensive, or provide delayed feedback. We present OpenDosimeter ( www.opendosimeter.org ), an open hardware solution for real-time personal X-ray dose monitoring. Using a scintillator-based X-ray sensor on a custom board powered by a Raspberry Pi Pico, OpenDosimeter provides real-time feedback (1 Hz), data logging (10 hours), and battery-powered operation. A core innovation is that we calibrate the device using 241Am found in ionization smoke detectors. Specifically, we use the γ-emissions to spectrally calibrate the dosimeter, then calculate the effective dose from X-ray exposure using the scintillator absorption efficiency and energy-to-dose coefficients derived from public tabulated data. We demonstrate that this transparent approach enables dose rate readings with linear response between 0.1-1000 μSv/h at  ± 25% accuracy, tested for energies up to 120 keV. The maximum dose rate readings are limited by pile-up effects when approaching count rate saturation (~77,000 counts per second at  ~13 μs average pulse-processing time). The total cost for making an OpenDosimeter is <$100, which, combined with its open design, enables cost-effective local reproducibility on a global scale. This paper complements the open-source documentation by explaining the underlying technology, algorithms, and areas for future improvement.

辐射工作人员需要精确监测x射线照射情况,但现有的解决方案要么难以获得,要么价格昂贵,要么提供延迟的反馈。我们提出了OpenDosimeter (www.opendosimeter.org),这是一种用于实时个人x射线剂量监测的开放式硬件解决方案。OpenDosimeter采用基于闪烁体的x射线传感器,安装在由Raspberry Pi Pico驱动的定制板上,提供实时反馈(1hz)、数据记录(10小时)和电池供电。一个核心创新是我们使用电离烟雾探测器中的241Am来校准设备。具体来说,我们使用γ辐射光谱校准剂量计,然后使用闪烁体吸收效率和从公开表格数据中得出的能量-剂量系数计算x射线照射的有效剂量。我们证明,这种透明的方法可以在±25%的精度下实现0.1-1000 μSv/h的线性响应剂量率读数,测试能量高达120 keV。当接近计数率饱和时,最大剂量率读数受到堆积效应的限制(在~13 μs的平均脉冲处理时间下每秒~77,000个计数)。制作一个开放剂量计的总成本是
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引用次数: 0
Shape-morphable origami electromagnetic waveguides. 可变形折纸电磁波导。
Pub Date : 2025-12-01 DOI: 10.1038/s44172-025-00539-7
Nikhil Ashok, Sangwoo Suk, Sven G Bilén, Xin Ning

Electromagnetic waveguides are widely used in spacecraft, naval, electrical, and communication systems for transferring microwave energy. Conventional designs are typically rigid and bulky, offering little shape adaptability. This limits their use in confined spaces or systems requiring compact storage and high adaptability. Here we report highly shape-morphable origami electromagnetic waveguides that fold, deploy, and change shape. Inspired by origami folding techniques, including shopping bags and bellows designs, these waveguides demonstrate low-loss, robust microwave energy transmission in numerical and experimental studies. Results demonstrate that highly shape-morphable electromagnetic waveguides may effectively replace rigid counterparts including straight, twisted, and bent waveguides. This research employs a combined analytical and experimental framework to study the kinematics and mechanics of key geometries, particularly rectangular straight and twist bellows designs, offering rigorous structural design guidance. Engineering advancements and fundamental studies in this work lay the foundation for future adaptive microwave energy delivery waveguides.

电磁波导广泛应用于航天器、舰船、电气和通信系统中,用于传输微波能量。传统的设计通常是刚性和笨重的,提供很少的形状适应性。这限制了它们在密闭空间或需要紧凑存储和高适应性的系统中的使用。在这里,我们报告高度形状可变形的折纸电磁波导折叠,部署和改变形状。受折纸折叠技术的启发,包括购物袋和风箱设计,这些波导在数值和实验研究中展示了低损耗,强大的微波能量传输。结果表明,高度可变形的电磁波导可以有效地取代刚性波导,包括直波导、扭曲波导和弯曲波导。本研究采用分析与实验相结合的框架研究关键几何形状的运动学和力学,特别是矩形直波纹管和扭转波纹管的设计,为结构设计提供严格的指导。本工作的工程进展和基础研究为未来的自适应微波能量传输波导奠定了基础。
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引用次数: 0
Efficient air purification using porous ceramic-based bubble-enhanced filtration system. 高效空气净化采用多孔陶瓷基气泡增强过滤系统。
Pub Date : 2025-11-29 DOI: 10.1038/s44172-025-00559-3
Junkai Ren, Ran Gao, Angui Li, Thomas Olofsson, Bingye Song, Ao Tian, Yingying Wang, Yibu Gao, Ying Zhang, Changqing Yang

Conventional dry filtration materials present a high initial efficiency but suffer from poor regenerability and limited functionality. Conversely, liquid-based purification strategies leverage the high capture potential of gas-liquid interfaces, but face challenges such as insufficient material strength, complex fabrication, and difficulties in large-scale application. Here, we proposed a porous ceramic-based bubble-enhanced filtration system (PCBEFS). The proposed system employs tunable porous ceramics as bubble generators in the water medium, thereby enabling highly efficient wet removal of particulate matter, while simultaneously providing air humidification, formaldehyde removal, and antibacterial functions. Furthermore, we established an empirical mathematical model linking pore structure, bubble characteristics, and removal performance, which elucidates the structure-activity relationship and presents insights into the capture mechanism jointly governed by porous ceramics and gas-liquid interfaces. PCBEFS addresses the limitations of the existing liquid-based purification systems and contributes substantially to multifunctional indoor air pollution control with strong engineering potential.

传统的干式过滤材料初始效率高,但可再生性差,功能有限。相反,基于液体的净化策略利用了气液界面的高捕获潜力,但面临着材料强度不足、制造复杂和大规模应用困难等挑战。在此,我们提出了一种多孔陶瓷基气泡增强过滤系统(PCBEFS)。该系统采用可调多孔陶瓷作为水介质中的气泡发生器,从而实现高效的湿法去除颗粒物,同时提供空气加湿、甲醛去除和抗菌功能。此外,我们建立了连接孔隙结构、气泡特征和去除性能的经验数学模型,阐明了结构-活性关系,并对多孔陶瓷和气液界面共同控制的捕获机制提出了见解。PCBEFS解决了现有液体净化系统的局限性,对多功能室内空气污染控制有很大的贡献,具有很强的工程潜力。
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引用次数: 0
Single photon event-driven 3D imaging. 单光子事件驱动的三维成像。
Pub Date : 2025-11-29 DOI: 10.1038/s44172-025-00555-7
Alex Vicente Sola, Matthias Aquilina, Paul Kirkland, Ashley Lyons

Event-based imaging is at the forefront of high-speed sensing applications due to the low latency of asynchronous detection and low data volume. Conventionally, events used in this form of sensing correspond to changes in intensity on the microsecond scale, this inherently makes the approach incompatible with scenarios where single photon detection is required such as single photon Light Detection and Ranging (LiDAR), and low-light-level imaging. Here we propose a new imaging modality which is driven instead by events generated from the detection of individual photons. We use a form of single-pixel imaging in which information from a 3-Dimensional scene is encoded entirely in the time-of-arrival of the photons such that each detected photon can be used to update an estimation of all transverse positions simultaneously. The image reconstruction is performed by a Spiking Convolutional Neural Network (SCNN) which has a natural complementarity with single photon detection that allows the scheme to run fully asynchronously and be driven by the detection of each individual photon. Our approach for processing LiDAR information asynchronously, driven by each detected photon, has the potential for minimal latency 3D imaging and sensing even in weak light conditions with applications in high speed target detection and robotics.

由于异步检测的低延迟和低数据量,基于事件的成像处于高速传感应用的前沿。通常,在这种形式的传感中使用的事件对应于微秒尺度上的强度变化,这本质上使得该方法与需要单光子探测的场景不兼容,例如单光子光探测和测距(LiDAR),以及微光成像。在这里,我们提出了一种新的成像模式,它是由单个光子探测产生的事件驱动的。我们使用一种单像素成像形式,其中来自三维场景的信息完全在光子到达时间内编码,这样每个检测到的光子可以用来同时更新所有横向位置的估计。图像重建由一个脉冲卷积神经网络(SCNN)执行,该网络与单光子检测具有天然的互补性,允许该方案完全异步运行,并由每个单个光子的检测驱动。我们异步处理激光雷达信息的方法,由每个检测到的光子驱动,即使在弱光条件下,也有可能实现最小延迟的3D成像和传感,并应用于高速目标检测和机器人技术。
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引用次数: 0
Reliable and efficient transcranial magnetic stimulation-electroencephalography (TMS-EEG) using ultra-thin active electrodes. 使用超薄有源电极可靠高效的经颅磁刺激-脑电图(TMS-EEG)。
Pub Date : 2025-11-28 DOI: 10.1038/s44172-025-00538-8
Johannes Gruenwald, Leonhard Schreiner, Sebastian Sieghartsleitner, Alexandru Buzamat, Giovanni Lombardi, Antonio Calzone, Marco Fummo, Slobodan Tanackovic, Marian-Silviu Poboroniuc, Rossella Spataro, Agnese Zazio, Marta Bortoletto, Christoph Guger

Transcranial magnetic stimulation combined with electroencephalography enables direct assessment of cortical excitability and connectivity via stimulation-evoked responses. While passive electrodes remain the gold standard, they require extensive preparation and are sensitive to contact quality, whereas active electrodes are easier to use but limited by increased height and larger decay artifacts. Here we introduce an ultra-thin active electrode system combined with hardware- and software-based artifact suppression. We collected electroencephalographic data from 10 healthy adults in Austria in 2024, recording brain responses with both active and passive electrodes during stimulation of the left primary motor cortex. We analyzed early and late responses for similarity and amplitude variability and found high consistency between electrode types, with stable waveforms after 20-30 trials. Response amplitudes did not differ significantly between electrode types. These findings demonstrate that active electrode systems can provide reliable and efficient recordings, supporting their broader use in stimulation-electroencephalography research.

经颅磁刺激结合脑电图可以通过刺激诱发反应直接评估皮层的兴奋性和连通性。虽然无源电极仍然是金标准,但它们需要大量的准备,并且对接触质量敏感,而有源电极更容易使用,但受到高度增加和更大的衰减伪影的限制。本文介绍了一种结合硬件和软件抑制伪影的超薄有源电极系统。我们于2024年在奥地利收集了10名健康成年人的脑电图数据,记录了在刺激左初级运动皮层时大脑的主动和被动电极反应。我们分析了早期和晚期响应的相似性和幅度可变性,发现电极类型之间具有高度一致性,经过20-30次试验后波形稳定。不同电极类型的反应幅度无显著差异。这些发现表明,有源电极系统可以提供可靠和有效的记录,支持其在刺激脑电图研究中的广泛应用。
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引用次数: 0
Object detection as an aid for locating the prostate in surface-based abdominal ultrasound images. 在基于表面的腹部超声图像中,目标检测作为定位前列腺的辅助。
Pub Date : 2025-11-28 DOI: 10.1038/s44172-025-00550-y
Rory D Bennett, Tristan Barrett, Vincent J Gnanapragasam, Zion Tsz Ho Tse

Automatic object detection is increasingly used in the medical field to enhance clinical workflows before, during, and after diagnosis of various conditions. One example is prostate detection and prostate volume estimation, which can aid in triaging patients for prostate cancer through risk-stratification using prostate-specific antigen density. In this paper, a baseline prostate detection framework is presented, highlighting that current state-of-the-art object detection models can detect the prostate in difficult to interpret surface-based ultrasound images. A 5-fold cross-validation study returned intersection-over-union, precision, recall, F1, and average-precision values above 0.7 with real-time capabilities possible. Additionally, a simple size calculation based on the detection results showed high correlation with ground truth measurements, with Pearson Correlation Coefficients ranging from 0.55 to 0.84 for prostate volume estimates. These findings will contribute to the development of a real-time prostate detection and size estimation platform for prostate cancer risk-stratification to reduce unnecessary biopsy rates in healthcare systems.

自动目标检测越来越多地应用于医疗领域,以增强各种疾病诊断之前,期间和之后的临床工作流程。一个例子是前列腺检测和前列腺体积估计,它可以通过使用前列腺特异性抗原密度进行风险分层来帮助诊断前列腺癌患者。本文提出了一个基线前列腺检测框架,强调当前最先进的目标检测模型可以在难以解释的基于表面的超声图像中检测前列腺。一项5倍交叉验证研究返回的交叉-超联合、精度、召回率、F1和平均精度值都在0.7以上,并且可能具有实时功能。此外,基于检测结果的简单大小计算显示与基础真值测量高度相关,前列腺体积估计值的Pearson相关系数范围为0.55至0.84。这些发现将有助于开发前列腺癌风险分层的实时前列腺检测和大小估计平台,以减少医疗保健系统中不必要的活检率。
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引用次数: 0
Cognitive embodied learning for anomaly active target tracking. 异常主动目标跟踪的认知具身学习。
Pub Date : 2025-11-27 DOI: 10.1038/s44172-025-00556-6
Qihui Wu, Jiahao Li, Fuhui Zhou, Jiahuan Ji, Haoyang Wang, Hongtao Liang, Kai-Kuang Ma

The primary challenge in active object tracking (AOT) lies in maintaining robust and accurate tracking performance in the complex physical scenarios. Existing end-to-end frameworks based on deep learning and reinforcement learning often struggle with high computational costs, data dependency, and limited generalization, hindering their performance in practical applications. Although embodied intelligence (EI) is promising to enable agents to learn from physical interactions, it cannot tackle severe anomalies happened in the complex scenarios. In order to address this issue, here we propose a novel embodied learning method, called the Cognitive Embodied Learning (CEL), which is inspired by the dual decision-making system of the human brain. The CEL can dynamically switch between normal tracking and anomaly handling modes, supported by specialized modules including the anomaly cognition module, the rule reasoning module, and the anomaly elimination module. Moreover, we further introduce the categorical objective function to address function non-measurability and data confusion caused by severe anomalies. Extensive unmanned aerial vehicle anomaly active target tracking experiments in both simulated and real-world scenarios demonstrate the superior performance of our method. Compared to the state-of-the-art methods, the CEL achieves a 361.4% increase in the success rate and a 54.4% improvement of the task completion efficiency, which highlights the potential of CEL to advance the field of AOT and open new avenues for more robust and intelligent tracking systems in the challenging environments.

主动目标跟踪(AOT)的主要挑战在于如何在复杂的物理场景中保持鲁棒和准确的跟踪性能。现有的基于深度学习和强化学习的端到端框架往往存在计算成本高、数据依赖和泛化有限的问题,阻碍了它们在实际应用中的表现。虽然具身智能(EI)有望使智能体从物理交互中学习,但它无法处理复杂场景中发生的严重异常。为了解决这一问题,我们提出了一种新的具身学习方法,称为认知具身学习(CEL),它的灵感来自于人类大脑的双重决策系统。CEL可以在正常跟踪和异常处理模式之间动态切换,由异常认知模块、规则推理模块和异常消除模块等专门模块提供支持。此外,我们进一步引入了分类目标函数,以解决严重异常导致的函数不可测量性和数据混乱问题。在模拟和现实场景下进行的大量无人机异常主动目标跟踪实验证明了该方法的优越性能。与最先进的方法相比,CEL的成功率提高了361.4%,任务完成效率提高了54.4%,这凸显了CEL在推进AOT领域的潜力,并为在具有挑战性的环境中开发更强大、更智能的跟踪系统开辟了新的途径。
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引用次数: 0
Thermomagnetic generators for ultra-low-grade marine thermal energy harvesting. 用于超低品位海洋热能收集的热磁发电机。
Pub Date : 2025-11-27 DOI: 10.1038/s44172-025-00542-y
Erick Moreno Resendiz, Tavis Peterson, Ravi Anant Kishore

Low-grade thermal gradients in marine environments represent an underexploited energy source for autonomous sensing and monitoring. Converting such small temperature differences into usable electrical power remains a key challenge for ocean-deployed systems. We present a deployable thermomagnetic generator thoroughly characterized for marine-relevant energy harvesting. The device powers an internet-connected sensor and harvests ultra-low temperature differences akin to those at the ocean surface. It draws heat from water and rejects it to ambient air, operating optimally at a temperature difference (ΔT) of ~7.5 °C. Laboratory prototypes generated up to 6.7 mW at ΔT ~ 10 °C with gentle airflow (~1 m s-1). A separate controlled wave-tank demonstration validated stable operation and sensor powering under marine-like boundary conditions. Given its voltage and power margins, the generator could sustain multiple sensor nodes. Scalability and material assessments identify modular deployment and non-rare-earth alternatives as pathways toward practical marine energy harvesting and low-grade waste-heat recovery.

海洋环境中的低等级热梯度是自主传感和监测的未充分开发的能源。将如此微小的温差转化为可用的电能,仍然是海洋部署系统面临的一个关键挑战。我们提出了一种可展开的热磁发电机,完全具有海洋相关能量收集的特点。该设备为连接互联网的传感器提供动力,并收集类似于海洋表面的超低温差异。它从水中吸收热量并将其排出到周围空气中,在~7.5°C的温差(ΔT)下运行最佳。实验室原型在ΔT ~ 10°C下产生高达6.7 mW的功率,气流温和(~1 m s-1)。一个独立的受控波浪槽演示验证了在类似海洋的边界条件下的稳定运行和传感器供电。考虑到它的电压和功率余量,发电机可以维持多个传感器节点。可扩展性和材料评估确定了模块化部署和非稀土替代品是实现实际海洋能源收集和低品位废热回收的途径。
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引用次数: 0
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Communications engineering
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