Pub Date : 2025-12-04DOI: 10.1038/s44172-025-00558-4
Yufen Wang, Ya Ji, Xiaofeng Luo, Tingting Zhu, Bing-Jie Ni, Yiwen Liu
Medium-chain fatty acids (MCFAs) are carbon-neutral alternative to petroleum-derived chemicals, offering sustainable valorization for waste activated sludge. Current bioproduction systems, however, face a critical dual bottleneck stemming from complex sludge matrices and inefficient carbon flux regulation. Here, we develop a stage-optimized modulation strategy employing alkaline biochar (AlkBC)-ferrate to sequentially enhance sludge solubilization and targeted MCFA-producing fermentation. Maximum MCFA production reaches 10495.0 mg chemical oxygen demand L-1, 20.6-, 15.2- and 2.3-fold higher than the control, AlkBC-alone and ferrate-alone groups, respectively. Mechanistically, AlkBC initiates ferrate activation to produce metastable Fe(IV)/Fe(V) intermediates via physical adsorption, electron donation, and oxygen-functionalized coordination. High-valent Fe species oxidation coupled with AlkBC-elevated alkalinity efficiently disrupts sludge polymerized structure and drives bioconversion of released organics. Simultaneously, AlkBC is structurally reconfigured due to ferrate oxidation with surface-loaded Fe₂O3 as active component, substantially enhancing chain elongation. Furthermore, AlkBC-ferrate enriches key functional bacteria while suppressing methanogens, steering carbon flux towards MCFA production.
{"title":"Staged modulation using synergistic alkaline biochar-ferrate enhances medium-chain fatty acid production from waste activated sludge.","authors":"Yufen Wang, Ya Ji, Xiaofeng Luo, Tingting Zhu, Bing-Jie Ni, Yiwen Liu","doi":"10.1038/s44172-025-00558-4","DOIUrl":"10.1038/s44172-025-00558-4","url":null,"abstract":"<p><p>Medium-chain fatty acids (MCFAs) are carbon-neutral alternative to petroleum-derived chemicals, offering sustainable valorization for waste activated sludge. Current bioproduction systems, however, face a critical dual bottleneck stemming from complex sludge matrices and inefficient carbon flux regulation. Here, we develop a stage-optimized modulation strategy employing alkaline biochar (AlkBC)-ferrate to sequentially enhance sludge solubilization and targeted MCFA-producing fermentation. Maximum MCFA production reaches 10495.0 mg chemical oxygen demand L<sup>-1</sup>, 20.6-, 15.2- and 2.3-fold higher than the control, AlkBC-alone and ferrate-alone groups, respectively. Mechanistically, AlkBC initiates ferrate activation to produce metastable Fe(IV)/Fe(V) intermediates via physical adsorption, electron donation, and oxygen-functionalized coordination. High-valent Fe species oxidation coupled with AlkBC-elevated alkalinity efficiently disrupts sludge polymerized structure and drives bioconversion of released organics. Simultaneously, AlkBC is structurally reconfigured due to ferrate oxidation with surface-loaded Fe₂O<sub>3</sub> as active component, substantially enhancing chain elongation. Furthermore, AlkBC-ferrate enriches key functional bacteria while suppressing methanogens, steering carbon flux towards MCFA production.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"5"},"PeriodicalIF":0.0,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12770428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145679465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-02DOI: 10.1038/s44172-025-00562-8
Yunhui Xie, James A Grant-Jacob, Matthew Praeger, Michalis N Zervas, Ben Mills
Coherent Beam Combination (CBC) presents a promising solution to circumvent the power-scaling limitations of High-Power Fiber Lasers (HPFLs) by spatially combining the outputs of multiple independently pumped fibres. This parallel pumping configuration allows each fibre to operate below the critical threshold that would otherwise lead to instability, whilst their combined output exceeds the maximum power achievable from a stably operating HPFL. In this work, we demonstrate that manipulating the relative phases between fibre outputs extends the capabilities of CBC to approximate the phase profiles of optical elements such as spherical lenses, axicon lenses, and spiral phase plates, enabling versatile beam focus shaping and steering. We further show that the combined beam focus, whether coherently combined or shaped into a bespoke profile (e.g. Bessel-like, orbital angular momentum), can be steered and rotated in three-dimensional space through phase-only control. These results are experimentally validated through spatial light modulation to simulate collimated fibre outputs with controllable relative phases. Our findings advance CBC systems beyond mere power scaling, offering pathways for highly versatile beam shaping and steering, with implications for next-generation multifunctional optical power delivery systems.
{"title":"Exploring five types of beam shaping using tiled-aperture coherent beam combining.","authors":"Yunhui Xie, James A Grant-Jacob, Matthew Praeger, Michalis N Zervas, Ben Mills","doi":"10.1038/s44172-025-00562-8","DOIUrl":"10.1038/s44172-025-00562-8","url":null,"abstract":"<p><p>Coherent Beam Combination (CBC) presents a promising solution to circumvent the power-scaling limitations of High-Power Fiber Lasers (HPFLs) by spatially combining the outputs of multiple independently pumped fibres. This parallel pumping configuration allows each fibre to operate below the critical threshold that would otherwise lead to instability, whilst their combined output exceeds the maximum power achievable from a stably operating HPFL. In this work, we demonstrate that manipulating the relative phases between fibre outputs extends the capabilities of CBC to approximate the phase profiles of optical elements such as spherical lenses, axicon lenses, and spiral phase plates, enabling versatile beam focus shaping and steering. We further show that the combined beam focus, whether coherently combined or shaped into a bespoke profile (e.g. Bessel-like, orbital angular momentum), can be steered and rotated in three-dimensional space through phase-only control. These results are experimentally validated through spatial light modulation to simulate collimated fibre outputs with controllable relative phases. Our findings advance CBC systems beyond mere power scaling, offering pathways for highly versatile beam shaping and steering, with implications for next-generation multifunctional optical power delivery systems.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12780195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-02DOI: 10.1038/s44172-025-00541-z
Xuan Phuc Le, Ludovic Mayer, Simone Magaletti, Martin Schmidt, Jean-François Roch, Thierry Debuisschert
The nitrogen-vacancy (NV) center is a defect in diamond whose spin state can be read optically by exploiting its photoluminescence or electrically by exploiting its charge generation rate under illumination, both of which being spin-dependent. The latter method offers numerous opportunities in terms of integration and performance compared to conventional optical readout. Here, we investigate the physical properties of a graphitic-diamond-graphitic structure under illumination. We show how, for a type IIa diamond material, electron-hole pairs generated by an ensemble of NV centers lead to a p-type material upon illumination, making this all-carbon structure equivalent to two back-to-back Schottky diodes. We analyze how the reverse current flowing upon illumination changes as a function of bias voltage and radiofrequency-induced excitation of the NV ensemble spin resonances. Furthermore, we demonstrate how an additional field effect arising from the illumination scheme affects the reverse current, resulting in a photoelectrical signal that can exceed the optical signal under the same illumination conditions.
{"title":"Field-effect detected magnetic resonance of nitrogen-vacancy centers in diamond based on all-carbon Schottky contacts.","authors":"Xuan Phuc Le, Ludovic Mayer, Simone Magaletti, Martin Schmidt, Jean-François Roch, Thierry Debuisschert","doi":"10.1038/s44172-025-00541-z","DOIUrl":"10.1038/s44172-025-00541-z","url":null,"abstract":"<p><p>The nitrogen-vacancy (NV) center is a defect in diamond whose spin state can be read optically by exploiting its photoluminescence or electrically by exploiting its charge generation rate under illumination, both of which being spin-dependent. The latter method offers numerous opportunities in terms of integration and performance compared to conventional optical readout. Here, we investigate the physical properties of a graphitic-diamond-graphitic structure under illumination. We show how, for a type IIa diamond material, electron-hole pairs generated by an ensemble of NV centers lead to a p-type material upon illumination, making this all-carbon structure equivalent to two back-to-back Schottky diodes. We analyze how the reverse current flowing upon illumination changes as a function of bias voltage and radiofrequency-induced excitation of the NV ensemble spin resonances. Furthermore, we demonstrate how an additional field effect arising from the illumination scheme affects the reverse current, resulting in a photoelectrical signal that can exceed the optical signal under the same illumination conditions.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"4 1","pages":"209"},"PeriodicalIF":0.0,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12672660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1038/s44172-025-00561-9
Franz Wegner, Thomas Friedrich, Patrick Naoki Elfers, Florian Kleefeldt, Dominik Peter, Philipp Gruschwitz, Teresa Reichl, Johanna Günther, Thomas Kampf, Martin A Rückert, Volker C Behr, Thorsten M Buzug, Roman Kloeckner, Jörg Barkhausen, Thorsten A Bley, Patrick Vogel, Viktor Hartung
Magnetic Particle Imaging (MPI) is a preclinical imaging modality with potential for future clinical usage. The radiation-free guidance of endovascular interventions with MPI is especially promising. Here, we present a safety study on the heating of metallic medical implants during MPI measurements under realistic conditions in an extracorporeally-perfused cadaver model. The measurements were conducted by fiberoptic thermometers and showed no detectable heating of the tested endovascular devices in the cadaver model. A temperature increase of no more than 0.11 K was observed on the surface of the investigated proximal femoral nail. The in vitro testing of orthopedic prostheses (knee and hip) revealed a slight heating effect of 0.45 K. The dependence of heating on the applied excitation frequency was measured. Overall, the tested repertoire of implants did not heat by a clinically-relevant amount in a human-sized MPI-scanner under realistic conditions, indicating their safe usage in future clinical applications.
{"title":"Towards clinical magnetic particle imaging: safety measurements of medical implants in a human cadaver model.","authors":"Franz Wegner, Thomas Friedrich, Patrick Naoki Elfers, Florian Kleefeldt, Dominik Peter, Philipp Gruschwitz, Teresa Reichl, Johanna Günther, Thomas Kampf, Martin A Rückert, Volker C Behr, Thorsten M Buzug, Roman Kloeckner, Jörg Barkhausen, Thorsten A Bley, Patrick Vogel, Viktor Hartung","doi":"10.1038/s44172-025-00561-9","DOIUrl":"10.1038/s44172-025-00561-9","url":null,"abstract":"<p><p>Magnetic Particle Imaging (MPI) is a preclinical imaging modality with potential for future clinical usage. The radiation-free guidance of endovascular interventions with MPI is especially promising. Here, we present a safety study on the heating of metallic medical implants during MPI measurements under realistic conditions in an extracorporeally-perfused cadaver model. The measurements were conducted by fiberoptic thermometers and showed no detectable heating of the tested endovascular devices in the cadaver model. A temperature increase of no more than 0.11 K was observed on the surface of the investigated proximal femoral nail. The in vitro testing of orthopedic prostheses (knee and hip) revealed a slight heating effect of 0.45 K. The dependence of heating on the applied excitation frequency was measured. Overall, the tested repertoire of implants did not heat by a clinically-relevant amount in a human-sized MPI-scanner under realistic conditions, indicating their safe usage in future clinical applications.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"210"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12673122/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1038/s44172-025-00540-0
Norah Ger, Alice Ku, Jasmyn Lopez, N Robert Bennett, Jia Wang, Grace Ateka, Enoch Anyenda, Matthias Rosezky, Pamela Kilavi, Adam S Wang, Kian Shaker
Radiation workers need accurate monitoring of X-ray exposure, but existing solutions are either inaccessible, expensive, or provide delayed feedback. We present OpenDosimeter ( www.opendosimeter.org ), an open hardware solution for real-time personal X-ray dose monitoring. Using a scintillator-based X-ray sensor on a custom board powered by a Raspberry Pi Pico, OpenDosimeter provides real-time feedback (1 Hz), data logging (10 hours), and battery-powered operation. A core innovation is that we calibrate the device using 241Am found in ionization smoke detectors. Specifically, we use the γ-emissions to spectrally calibrate the dosimeter, then calculate the effective dose from X-ray exposure using the scintillator absorption efficiency and energy-to-dose coefficients derived from public tabulated data. We demonstrate that this transparent approach enables dose rate readings with linear response between 0.1-1000 μSv/h at ± 25% accuracy, tested for energies up to 120 keV. The maximum dose rate readings are limited by pile-up effects when approaching count rate saturation (~77,000 counts per second at ~13 μs average pulse-processing time). The total cost for making an OpenDosimeter is <$100, which, combined with its open design, enables cost-effective local reproducibility on a global scale. This paper complements the open-source documentation by explaining the underlying technology, algorithms, and areas for future improvement.
辐射工作人员需要精确监测x射线照射情况,但现有的解决方案要么难以获得,要么价格昂贵,要么提供延迟的反馈。我们提出了OpenDosimeter (www.opendosimeter.org),这是一种用于实时个人x射线剂量监测的开放式硬件解决方案。OpenDosimeter采用基于闪烁体的x射线传感器,安装在由Raspberry Pi Pico驱动的定制板上,提供实时反馈(1hz)、数据记录(10小时)和电池供电。一个核心创新是我们使用电离烟雾探测器中的241Am来校准设备。具体来说,我们使用γ辐射光谱校准剂量计,然后使用闪烁体吸收效率和从公开表格数据中得出的能量-剂量系数计算x射线照射的有效剂量。我们证明,这种透明的方法可以在±25%的精度下实现0.1-1000 μSv/h的线性响应剂量率读数,测试能量高达120 keV。当接近计数率饱和时,最大剂量率读数受到堆积效应的限制(在~13 μs的平均脉冲处理时间下每秒~77,000个计数)。制作一个开放剂量计的总成本是
{"title":"OpenDosimeter: Open hardware personal X-ray dosimeter.","authors":"Norah Ger, Alice Ku, Jasmyn Lopez, N Robert Bennett, Jia Wang, Grace Ateka, Enoch Anyenda, Matthias Rosezky, Pamela Kilavi, Adam S Wang, Kian Shaker","doi":"10.1038/s44172-025-00540-0","DOIUrl":"10.1038/s44172-025-00540-0","url":null,"abstract":"<p><p>Radiation workers need accurate monitoring of X-ray exposure, but existing solutions are either inaccessible, expensive, or provide delayed feedback. We present OpenDosimeter ( www.opendosimeter.org ), an open hardware solution for real-time personal X-ray dose monitoring. Using a scintillator-based X-ray sensor on a custom board powered by a Raspberry Pi Pico, OpenDosimeter provides real-time feedback (1 Hz), data logging (10 hours), and battery-powered operation. A core innovation is that we calibrate the device using <sup>241</sup>Am found in ionization smoke detectors. Specifically, we use the γ-emissions to spectrally calibrate the dosimeter, then calculate the effective dose from X-ray exposure using the scintillator absorption efficiency and energy-to-dose coefficients derived from public tabulated data. We demonstrate that this transparent approach enables dose rate readings with linear response between 0.1-1000 μSv/h at ± 25% accuracy, tested for energies up to 120 keV. The maximum dose rate readings are limited by pile-up effects when approaching count rate saturation (~77,000 counts per second at ~13 μs average pulse-processing time). The total cost for making an OpenDosimeter is <$100, which, combined with its open design, enables cost-effective local reproducibility on a global scale. This paper complements the open-source documentation by explaining the underlying technology, algorithms, and areas for future improvement.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"4 1","pages":"207"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12669598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1038/s44172-025-00539-7
Nikhil Ashok, Sangwoo Suk, Sven G Bilén, Xin Ning
Electromagnetic waveguides are widely used in spacecraft, naval, electrical, and communication systems for transferring microwave energy. Conventional designs are typically rigid and bulky, offering little shape adaptability. This limits their use in confined spaces or systems requiring compact storage and high adaptability. Here we report highly shape-morphable origami electromagnetic waveguides that fold, deploy, and change shape. Inspired by origami folding techniques, including shopping bags and bellows designs, these waveguides demonstrate low-loss, robust microwave energy transmission in numerical and experimental studies. Results demonstrate that highly shape-morphable electromagnetic waveguides may effectively replace rigid counterparts including straight, twisted, and bent waveguides. This research employs a combined analytical and experimental framework to study the kinematics and mechanics of key geometries, particularly rectangular straight and twist bellows designs, offering rigorous structural design guidance. Engineering advancements and fundamental studies in this work lay the foundation for future adaptive microwave energy delivery waveguides.
{"title":"Shape-morphable origami electromagnetic waveguides.","authors":"Nikhil Ashok, Sangwoo Suk, Sven G Bilén, Xin Ning","doi":"10.1038/s44172-025-00539-7","DOIUrl":"10.1038/s44172-025-00539-7","url":null,"abstract":"<p><p>Electromagnetic waveguides are widely used in spacecraft, naval, electrical, and communication systems for transferring microwave energy. Conventional designs are typically rigid and bulky, offering little shape adaptability. This limits their use in confined spaces or systems requiring compact storage and high adaptability. Here we report highly shape-morphable origami electromagnetic waveguides that fold, deploy, and change shape. Inspired by origami folding techniques, including shopping bags and bellows designs, these waveguides demonstrate low-loss, robust microwave energy transmission in numerical and experimental studies. Results demonstrate that highly shape-morphable electromagnetic waveguides may effectively replace rigid counterparts including straight, twisted, and bent waveguides. This research employs a combined analytical and experimental framework to study the kinematics and mechanics of key geometries, particularly rectangular straight and twist bellows designs, offering rigorous structural design guidance. Engineering advancements and fundamental studies in this work lay the foundation for future adaptive microwave energy delivery waveguides.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"4 1","pages":"208"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12669762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145656413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-29DOI: 10.1038/s44172-025-00559-3
Junkai Ren, Ran Gao, Angui Li, Thomas Olofsson, Bingye Song, Ao Tian, Yingying Wang, Yibu Gao, Ying Zhang, Changqing Yang
Conventional dry filtration materials present a high initial efficiency but suffer from poor regenerability and limited functionality. Conversely, liquid-based purification strategies leverage the high capture potential of gas-liquid interfaces, but face challenges such as insufficient material strength, complex fabrication, and difficulties in large-scale application. Here, we proposed a porous ceramic-based bubble-enhanced filtration system (PCBEFS). The proposed system employs tunable porous ceramics as bubble generators in the water medium, thereby enabling highly efficient wet removal of particulate matter, while simultaneously providing air humidification, formaldehyde removal, and antibacterial functions. Furthermore, we established an empirical mathematical model linking pore structure, bubble characteristics, and removal performance, which elucidates the structure-activity relationship and presents insights into the capture mechanism jointly governed by porous ceramics and gas-liquid interfaces. PCBEFS addresses the limitations of the existing liquid-based purification systems and contributes substantially to multifunctional indoor air pollution control with strong engineering potential.
{"title":"Efficient air purification using porous ceramic-based bubble-enhanced filtration system.","authors":"Junkai Ren, Ran Gao, Angui Li, Thomas Olofsson, Bingye Song, Ao Tian, Yingying Wang, Yibu Gao, Ying Zhang, Changqing Yang","doi":"10.1038/s44172-025-00559-3","DOIUrl":"10.1038/s44172-025-00559-3","url":null,"abstract":"<p><p>Conventional dry filtration materials present a high initial efficiency but suffer from poor regenerability and limited functionality. Conversely, liquid-based purification strategies leverage the high capture potential of gas-liquid interfaces, but face challenges such as insufficient material strength, complex fabrication, and difficulties in large-scale application. Here, we proposed a porous ceramic-based bubble-enhanced filtration system (PCBEFS). The proposed system employs tunable porous ceramics as bubble generators in the water medium, thereby enabling highly efficient wet removal of particulate matter, while simultaneously providing air humidification, formaldehyde removal, and antibacterial functions. Furthermore, we established an empirical mathematical model linking pore structure, bubble characteristics, and removal performance, which elucidates the structure-activity relationship and presents insights into the capture mechanism jointly governed by porous ceramics and gas-liquid interfaces. PCBEFS addresses the limitations of the existing liquid-based purification systems and contributes substantially to multifunctional indoor air pollution control with strong engineering potential.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"4"},"PeriodicalIF":0.0,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12769571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-29DOI: 10.1038/s44172-025-00555-7
Alex Vicente Sola, Matthias Aquilina, Paul Kirkland, Ashley Lyons
Event-based imaging is at the forefront of high-speed sensing applications due to the low latency of asynchronous detection and low data volume. Conventionally, events used in this form of sensing correspond to changes in intensity on the microsecond scale, this inherently makes the approach incompatible with scenarios where single photon detection is required such as single photon Light Detection and Ranging (LiDAR), and low-light-level imaging. Here we propose a new imaging modality which is driven instead by events generated from the detection of individual photons. We use a form of single-pixel imaging in which information from a 3-Dimensional scene is encoded entirely in the time-of-arrival of the photons such that each detected photon can be used to update an estimation of all transverse positions simultaneously. The image reconstruction is performed by a Spiking Convolutional Neural Network (SCNN) which has a natural complementarity with single photon detection that allows the scheme to run fully asynchronously and be driven by the detection of each individual photon. Our approach for processing LiDAR information asynchronously, driven by each detected photon, has the potential for minimal latency 3D imaging and sensing even in weak light conditions with applications in high speed target detection and robotics.
{"title":"Single photon event-driven 3D imaging.","authors":"Alex Vicente Sola, Matthias Aquilina, Paul Kirkland, Ashley Lyons","doi":"10.1038/s44172-025-00555-7","DOIUrl":"10.1038/s44172-025-00555-7","url":null,"abstract":"<p><p>Event-based imaging is at the forefront of high-speed sensing applications due to the low latency of asynchronous detection and low data volume. Conventionally, events used in this form of sensing correspond to changes in intensity on the microsecond scale, this inherently makes the approach incompatible with scenarios where single photon detection is required such as single photon Light Detection and Ranging (LiDAR), and low-light-level imaging. Here we propose a new imaging modality which is driven instead by events generated from the detection of individual photons. We use a form of single-pixel imaging in which information from a 3-Dimensional scene is encoded entirely in the time-of-arrival of the photons such that each detected photon can be used to update an estimation of all transverse positions simultaneously. The image reconstruction is performed by a Spiking Convolutional Neural Network (SCNN) which has a natural complementarity with single photon detection that allows the scheme to run fully asynchronously and be driven by the detection of each individual photon. Our approach for processing LiDAR information asynchronously, driven by each detected photon, has the potential for minimal latency 3D imaging and sensing even in weak light conditions with applications in high speed target detection and robotics.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2025-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12764911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-28DOI: 10.1038/s44172-025-00538-8
Johannes Gruenwald, Leonhard Schreiner, Sebastian Sieghartsleitner, Alexandru Buzamat, Giovanni Lombardi, Antonio Calzone, Marco Fummo, Slobodan Tanackovic, Marian-Silviu Poboroniuc, Rossella Spataro, Agnese Zazio, Marta Bortoletto, Christoph Guger
Transcranial magnetic stimulation combined with electroencephalography enables direct assessment of cortical excitability and connectivity via stimulation-evoked responses. While passive electrodes remain the gold standard, they require extensive preparation and are sensitive to contact quality, whereas active electrodes are easier to use but limited by increased height and larger decay artifacts. Here we introduce an ultra-thin active electrode system combined with hardware- and software-based artifact suppression. We collected electroencephalographic data from 10 healthy adults in Austria in 2024, recording brain responses with both active and passive electrodes during stimulation of the left primary motor cortex. We analyzed early and late responses for similarity and amplitude variability and found high consistency between electrode types, with stable waveforms after 20-30 trials. Response amplitudes did not differ significantly between electrode types. These findings demonstrate that active electrode systems can provide reliable and efficient recordings, supporting their broader use in stimulation-electroencephalography research.
{"title":"Reliable and efficient transcranial magnetic stimulation-electroencephalography (TMS-EEG) using ultra-thin active electrodes.","authors":"Johannes Gruenwald, Leonhard Schreiner, Sebastian Sieghartsleitner, Alexandru Buzamat, Giovanni Lombardi, Antonio Calzone, Marco Fummo, Slobodan Tanackovic, Marian-Silviu Poboroniuc, Rossella Spataro, Agnese Zazio, Marta Bortoletto, Christoph Guger","doi":"10.1038/s44172-025-00538-8","DOIUrl":"10.1038/s44172-025-00538-8","url":null,"abstract":"<p><p>Transcranial magnetic stimulation combined with electroencephalography enables direct assessment of cortical excitability and connectivity via stimulation-evoked responses. While passive electrodes remain the gold standard, they require extensive preparation and are sensitive to contact quality, whereas active electrodes are easier to use but limited by increased height and larger decay artifacts. Here we introduce an ultra-thin active electrode system combined with hardware- and software-based artifact suppression. We collected electroencephalographic data from 10 healthy adults in Austria in 2024, recording brain responses with both active and passive electrodes during stimulation of the left primary motor cortex. We analyzed early and late responses for similarity and amplitude variability and found high consistency between electrode types, with stable waveforms after 20-30 trials. Response amplitudes did not differ significantly between electrode types. These findings demonstrate that active electrode systems can provide reliable and efficient recordings, supporting their broader use in stimulation-electroencephalography research.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":"4 1","pages":"206"},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12663230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-28DOI: 10.1038/s44172-025-00550-y
Rory D Bennett, Tristan Barrett, Vincent J Gnanapragasam, Zion Tsz Ho Tse
Automatic object detection is increasingly used in the medical field to enhance clinical workflows before, during, and after diagnosis of various conditions. One example is prostate detection and prostate volume estimation, which can aid in triaging patients for prostate cancer through risk-stratification using prostate-specific antigen density. In this paper, a baseline prostate detection framework is presented, highlighting that current state-of-the-art object detection models can detect the prostate in difficult to interpret surface-based ultrasound images. A 5-fold cross-validation study returned intersection-over-union, precision, recall, F1, and average-precision values above with real-time capabilities possible. Additionally, a simple size calculation based on the detection results showed high correlation with ground truth measurements, with Pearson Correlation Coefficients ranging from to for prostate volume estimates. These findings will contribute to the development of a real-time prostate detection and size estimation platform for prostate cancer risk-stratification to reduce unnecessary biopsy rates in healthcare systems.
{"title":"Object detection as an aid for locating the prostate in surface-based abdominal ultrasound images.","authors":"Rory D Bennett, Tristan Barrett, Vincent J Gnanapragasam, Zion Tsz Ho Tse","doi":"10.1038/s44172-025-00550-y","DOIUrl":"10.1038/s44172-025-00550-y","url":null,"abstract":"<p><p>Automatic object detection is increasingly used in the medical field to enhance clinical workflows before, during, and after diagnosis of various conditions. One example is prostate detection and prostate volume estimation, which can aid in triaging patients for prostate cancer through risk-stratification using prostate-specific antigen density. In this paper, a baseline prostate detection framework is presented, highlighting that current state-of-the-art object detection models can detect the prostate in difficult to interpret surface-based ultrasound images. A 5-fold cross-validation study returned intersection-over-union, precision, recall, F1, and average-precision values above <math><mi>0.7</mi></math> with real-time capabilities possible. Additionally, a simple size calculation based on the detection results showed high correlation with ground truth measurements, with Pearson Correlation Coefficients ranging from <math><mi>0.55</mi></math> to <math><mi>0.84</mi></math> for prostate volume estimates. These findings will contribute to the development of a real-time prostate detection and size estimation platform for prostate cancer risk-stratification to reduce unnecessary biopsy rates in healthcare systems.</p>","PeriodicalId":72644,"journal":{"name":"Communications engineering","volume":" ","pages":"217"},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12728191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145643398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}