首页 > 最新文献

Advances in Human Biology最新文献

英文 中文
Analysis of width/length ratio in maxillary anterior teeth among Gujarati young individuals: A cross-sectional study 古吉拉特年轻人上颌前牙宽长比的横断面分析
IF 0.4 Q4 BIOLOGY Pub Date : 2023-05-01 DOI: 10.4103/aihb.aihb_186_22
Bhagyashree H Dave, S. Mehta, Shreyansh P. Sutaria, P. Sutariya
Introduction: Correcting tooth size discrepancies are essential in achieving good dental and facial aesthetic in restorative and prosthetic dentistry. Hence, dental biometrics will be the most important key for an aesthetic restoration. This study aimed to analyse the width, length and width/length ratio related to the clinical crown of maxillary central incisors, lateral incisors and canines in adult Gujarati individuals. This study also aimed to check whether a correlation exists between the optimal tooth dimension guidelines for planning aesthetic restorations and natural tooth dimensions. Materials and Methods: Type III dental plaster casts were made from irreversible hydrocolloid impressions of 68 healthy adult participants. These casts were used to measure maxillary central incisors, lateral incisors and canines' maximum mesiodistal width and crown-root length with a digital vernier calliper (0.01 mm). The width/length ratio for each and every tooth was calculated. Results: The sample used in the study was 61.76% female and 38.24% male, with an age range of 18–30 years. 8.53 mm was the mean width value for the central incisors, lateral incisors 6.88 mm and canines 7.64 mm. The mean length was 9.80 mm for the central incisors, 8.25 mm for the lateral incisors and 9.29 mm for the canines. The average width/length ratio was 87% for the central incisors and 84% for the laterals and 83% for canines. Conclusion: The data received from the population studied are similar to previous research studies having similar methodology. However, great discrepancies in the absolute values were found when compared with other studies related to ideal tooth dimension guidelines on the aesthetic perception of dentists and personal preferences. The perception of what is considered natural seems to differ from what is considered aesthetically perfect.
引言:在修复和修复牙科中,矫正牙齿大小差异对于实现良好的牙齿和面部美学至关重要。因此,牙齿生物识别技术将是美容修复最重要的关键。本研究旨在分析成年古吉拉特人上颌中切牙、侧切牙和犬齿临床牙冠的宽度、长度和宽度/长度比。本研究还旨在检查规划美观修复的最佳牙齿尺寸指南与自然牙齿尺寸之间是否存在相关性。材料和方法:用68名健康成年参与者的不可逆水胶体印模制作III型牙膏模型。这些模型用于用数字游标卡尺(0.01mm)测量上颌中切牙、侧切牙和犬齿的最大近中宽度和冠根长度。计算每个齿的宽度/长度比。结果:研究中使用的样本为61.76%的女性和38.24%的男性,年龄范围为18-30岁。中切牙、侧切牙和犬齿的平均宽度分别为8.53mm、6.88mm和7.64mm。中切牙的平均长度分别为9.80mm、8.25mm和9.29mm。中切牙的平均宽度/长度比为87%,侧切牙为84%,犬齿为83%。结论:从研究人群中获得的数据与之前采用类似方法的研究相似。然而,与其他关于牙医美感和个人偏好的理想牙齿尺寸指南的研究相比,发现绝对值存在很大差异。对什么是自然的感知似乎与什么是审美完美的感知不同。
{"title":"Analysis of width/length ratio in maxillary anterior teeth among Gujarati young individuals: A cross-sectional study","authors":"Bhagyashree H Dave, S. Mehta, Shreyansh P. Sutaria, P. Sutariya","doi":"10.4103/aihb.aihb_186_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_186_22","url":null,"abstract":"Introduction: Correcting tooth size discrepancies are essential in achieving good dental and facial aesthetic in restorative and prosthetic dentistry. Hence, dental biometrics will be the most important key for an aesthetic restoration. This study aimed to analyse the width, length and width/length ratio related to the clinical crown of maxillary central incisors, lateral incisors and canines in adult Gujarati individuals. This study also aimed to check whether a correlation exists between the optimal tooth dimension guidelines for planning aesthetic restorations and natural tooth dimensions. Materials and Methods: Type III dental plaster casts were made from irreversible hydrocolloid impressions of 68 healthy adult participants. These casts were used to measure maxillary central incisors, lateral incisors and canines' maximum mesiodistal width and crown-root length with a digital vernier calliper (0.01 mm). The width/length ratio for each and every tooth was calculated. Results: The sample used in the study was 61.76% female and 38.24% male, with an age range of 18–30 years. 8.53 mm was the mean width value for the central incisors, lateral incisors 6.88 mm and canines 7.64 mm. The mean length was 9.80 mm for the central incisors, 8.25 mm for the lateral incisors and 9.29 mm for the canines. The average width/length ratio was 87% for the central incisors and 84% for the laterals and 83% for canines. Conclusion: The data received from the population studied are similar to previous research studies having similar methodology. However, great discrepancies in the absolute values were found when compared with other studies related to ideal tooth dimension guidelines on the aesthetic perception of dentists and personal preferences. The perception of what is considered natural seems to differ from what is considered aesthetically perfect.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"59 - 64"},"PeriodicalIF":0.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46272627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality audit of haematology laboratory: Challenges and opportunities 血液学实验室质量审核:挑战与机遇
IF 0.4 Q4 BIOLOGY Pub Date : 2023-05-01 DOI: 10.4103/aihb.aihb_197_22
K. Sudarshan, Subhashis Das, A. Hemalatha, K. Raju
Introduction: Laboratory results play an essential role in both medical decision-making and inpatient management. In many clinical scenarios, laboratory test results are essential to make the right diagnosis or choosing the suitable treatment regimen. The aims and objectives were to study 13 National Accreditation Board for Testing and Calibration Laboratories (NABL)-specific common quality indicators (QIs) in the haematology laboratory of a tertiary care teaching hospital. Materials and Methods: NABL accredited a laboratory-based, cross-sectional study done in the haematology laboratory of NABH-recognised tertiary care teaching hospital over 5 years from January 2017 to April 2022 with a sample size of 1586,096. Quality parameters studied include sample rejection rates, sample redo rates, routine turnaround time (TAT), critical reports and their TAT, corrected reports, staining quality etc. The QI rates were calculated on a monthly basis, and trends were analysed. P < 0.05 was considered statistically significant. Results: The most common error was clotted sample 634 (0.04%), followed by rejection due to the misidentification of sample 128 (0.008%). Several monthly critical alerts showed an upward trend (P = 0.045) which could be attributed to increased awareness amongst laboratory staff. Redo rates showed no significant change in trend over the study period. Conclusion: Updating the knowledge on laboratory services, adequate training of the staff and sensitisation about the importance of the QIs in all three phases will help minimise errors.
引言:实验室结果在医疗决策和住院管理中都发挥着重要作用。在许多临床情况下,实验室检测结果对于做出正确诊断或选择合适的治疗方案至关重要。目的和目的是研究13个国家检测和校准实验室认可委员会(NABL)——一家三级护理教学医院血液学实验室的特定通用质量指标(QIs)。材料和方法:NABL认可了一项基于实验室的横断面研究,该研究于2017年1月至2022年4月在NABH认可的三级护理教学医院的血液学实验室进行,历时5年,样本量为1586096。研究的质量参数包括样品拒绝率、样品重做率、常规周转时间(TAT)、关键报告及其TAT、校正报告、染色质量等。每月计算QI率,并分析趋势。P<0.05被认为具有统计学意义。结果:最常见的错误是凝结样本634(0.04%),其次是由于样本128(0.008%)的错误识别而被拒绝。几个月的严重警报显示出上升趋势(P=0.045),这可能归因于实验室工作人员的意识提高。重做率在研究期间的趋势没有显著变化。结论:在所有三个阶段,更新实验室服务知识、对员工进行充分培训以及提高对合格中介机构重要性的认识将有助于最大限度地减少错误。
{"title":"Quality audit of haematology laboratory: Challenges and opportunities","authors":"K. Sudarshan, Subhashis Das, A. Hemalatha, K. Raju","doi":"10.4103/aihb.aihb_197_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_197_22","url":null,"abstract":"Introduction: Laboratory results play an essential role in both medical decision-making and inpatient management. In many clinical scenarios, laboratory test results are essential to make the right diagnosis or choosing the suitable treatment regimen. The aims and objectives were to study 13 National Accreditation Board for Testing and Calibration Laboratories (NABL)-specific common quality indicators (QIs) in the haematology laboratory of a tertiary care teaching hospital. Materials and Methods: NABL accredited a laboratory-based, cross-sectional study done in the haematology laboratory of NABH-recognised tertiary care teaching hospital over 5 years from January 2017 to April 2022 with a sample size of 1586,096. Quality parameters studied include sample rejection rates, sample redo rates, routine turnaround time (TAT), critical reports and their TAT, corrected reports, staining quality etc. The QI rates were calculated on a monthly basis, and trends were analysed. P < 0.05 was considered statistically significant. Results: The most common error was clotted sample 634 (0.04%), followed by rejection due to the misidentification of sample 128 (0.008%). Several monthly critical alerts showed an upward trend (P = 0.045) which could be attributed to increased awareness amongst laboratory staff. Redo rates showed no significant change in trend over the study period. Conclusion: Updating the knowledge on laboratory services, adequate training of the staff and sensitisation about the importance of the QIs in all three phases will help minimise errors.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"75 - 79"},"PeriodicalIF":0.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45494806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of clinical parameters between the treatment of infrabony defects with and without concentrated growth factors in open flap debridement: In vivo study 开放式皮瓣清创术中应用和不应用浓缩生长因子治疗骨下缺损的临床参数比较:体内研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-05-01 DOI: 10.4103/aihb.aihb_123_22
Nancy Joshi, B. Dave, Viral Thakker, A. Dave, Mahendrakumar Katariya, Kandarp Raj
Introduction: This study aimed to clinically and radiographically compare the regenerative effects of open flap debridement alone and in combination with concentrated growth factor (CGF) in the treatment of periodontal three-walled infrabony defects. Materials and Methods: Fifteen patients who fulfilled the inclusion criteria were selected from the outpatient department of periodontology. A split-mouth study was conducted and bilateral or contralateral defects were divided into two groups using computer-generated randomisation sheets-control site (open flap debridement alone) and case site (open flap debridement with CGF). Clinical parameters were assessed at baseline, 1 month, 3 months and 6 months. Radiographic parameters were assessed at baseline and 6 months postoperatively. Results: At 3 and 6 months postoperatively, the test group showed statistically significant improvement in clinical parameters as compared to the control group. At 6 months postoperatively, the test group showed improved bone fill as compared to the control group. Conclusion: Present study indicates that CGF, as a biological material has the property to enhance wound healing and result in mean pocket depth reduction of periodontal infrabony defects. In addition, long-term, multicentered randomised, controlled clinical researches will be required to better understand the clinical and radiographic effects of CGF on periodontal regeneration.
前言:本研究旨在比较单纯开瓣清创与联合浓缩生长因子(CGF)治疗牙周三壁下颌骨缺损的再生效果。材料与方法:选取牙周病门诊符合纳入标准的患者15例。进行了一项裂口研究,并使用计算机生成的随机表将双侧或对侧缺陷分为两组-对照部位(单独开瓣清创)和病例部位(开瓣清创联合CGF)。在基线、1个月、3个月和6个月时评估临床参数。在基线和术后6个月评估影像学参数。结果:术后3、6个月,试验组临床参数较对照组改善有统计学意义。术后6个月,与对照组相比,实验组骨填充改善。结论:CGF作为一种生物材料,具有促进创面愈合和减少牙周下颌骨缺损平均袋深的作用。此外,还需要进行长期、多中心、随机对照的临床研究,以更好地了解CGF对牙周再生的临床和影像学影响。
{"title":"Comparison of clinical parameters between the treatment of infrabony defects with and without concentrated growth factors in open flap debridement: In vivo study","authors":"Nancy Joshi, B. Dave, Viral Thakker, A. Dave, Mahendrakumar Katariya, Kandarp Raj","doi":"10.4103/aihb.aihb_123_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_123_22","url":null,"abstract":"Introduction: This study aimed to clinically and radiographically compare the regenerative effects of open flap debridement alone and in combination with concentrated growth factor (CGF) in the treatment of periodontal three-walled infrabony defects. Materials and Methods: Fifteen patients who fulfilled the inclusion criteria were selected from the outpatient department of periodontology. A split-mouth study was conducted and bilateral or contralateral defects were divided into two groups using computer-generated randomisation sheets-control site (open flap debridement alone) and case site (open flap debridement with CGF). Clinical parameters were assessed at baseline, 1 month, 3 months and 6 months. Radiographic parameters were assessed at baseline and 6 months postoperatively. Results: At 3 and 6 months postoperatively, the test group showed statistically significant improvement in clinical parameters as compared to the control group. At 6 months postoperatively, the test group showed improved bone fill as compared to the control group. Conclusion: Present study indicates that CGF, as a biological material has the property to enhance wound healing and result in mean pocket depth reduction of periodontal infrabony defects. In addition, long-term, multicentered randomised, controlled clinical researches will be required to better understand the clinical and radiographic effects of CGF on periodontal regeneration.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"38 - 43"},"PeriodicalIF":0.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45788687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interaction of millimetre waves used in 5G network with cells and tissues of head-and-neck region: A literature review 5G网络中使用的毫米波与头颈部细胞和组织的相互作用:文献综述
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_133_22
Namrata Dagli, Rushabh J Dagli, L. Thangavelu
Fifth-generation mobile technology is supposed to revolutionise the world. It has many features which can benefit humankind, but at the same time, it will expose us to much radiation. Therefore, we need to understand the importance and ill effects of 5 G technology. An online literature search was conducted through PubMed and Scopus databases from April 2021 to May 2021, using the Boolean operators OR, AND and NOT and the keywords '5G Network', 'Human tissues', and 'Animal tissues'. The literature is very scarce in studies on the effects of millimetre waves on various tissues. A total of 1269 studies were identified, and 24 were selected for qualitative evidence synthesis. Randomised control trials, laboratory studies, in-vitro studies, in-vivo studies and ex-vivo studies were included. Data from the studies were collected using the data extraction form, and all the relevant information was summarized. Five of 24 studies were done on animals, four on humans, five on models, and ten on various cells. Ten of 24 studies demonstrated the harmful effects of millimetre waves. Results are ambivalent, and no association is found between particular frequency and impact on tissue, animals or humans. Pathophysiological effects observed in most studies were mild, reversible, and limited to the cellular level. Available evidence reported temperature rise after millimetre wave exposure, which was within safety limits. Any biological impact on a cellular level noticed due to radiation's thermal effects were insignificant and did not affect the organ level. However, only a few studies have mentioned non-thermal impact, but those effects should not be overlooked. Clinical trials on a large population and for a longer duration are required to establish the safety of millimetre waves before deploying a 5G network worldwide.
第五代移动技术被认为将彻底改变世界。它有许多可以造福人类的特征,但同时,它会使我们暴露在大量辐射中。因此,我们需要了解5G技术的重要性和不良影响。2021年4月至2021年5月,通过PubMed和Scopus数据库进行了在线文献搜索,使用布尔运算符OR、and和NOT以及关键字“5G网络”、“人体组织”和“动物组织”。关于毫米波对各种组织影响的研究文献很少。共确定了1269项研究,并选择了24项进行定性证据综合。包括随机对照试验、实验室研究、体外研究、体内研究和离体研究。使用数据提取表收集研究数据,并总结所有相关信息。24项研究中有5项针对动物,4项针对人类,5项针对模型,10项针对各种细胞。24项研究中有10项证明了毫米波的有害影响。结果是矛盾的,没有发现特定的频率和对组织、动物或人类的影响之间的联系。在大多数研究中观察到的病理生理作用是温和的、可逆的,并且仅限于细胞水平。现有证据表明,毫米波暴露后温度升高,在安全范围内。由于辐射的热效应,对细胞水平的任何生物影响都是微不足道的,不会影响器官水平。然而,只有少数研究提到了非热影响,但这些影响不应被忽视。在全球部署5G网络之前,需要在大量人群中进行更长时间的临床试验,以确定毫米波的安全性。
{"title":"Interaction of millimetre waves used in 5G network with cells and tissues of head-and-neck region: A literature review","authors":"Namrata Dagli, Rushabh J Dagli, L. Thangavelu","doi":"10.4103/aihb.aihb_133_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_133_22","url":null,"abstract":"Fifth-generation mobile technology is supposed to revolutionise the world. It has many features which can benefit humankind, but at the same time, it will expose us to much radiation. Therefore, we need to understand the importance and ill effects of 5 G technology. An online literature search was conducted through PubMed and Scopus databases from April 2021 to May 2021, using the Boolean operators OR, AND and NOT and the keywords '5G Network', 'Human tissues', and 'Animal tissues'. The literature is very scarce in studies on the effects of millimetre waves on various tissues. A total of 1269 studies were identified, and 24 were selected for qualitative evidence synthesis. Randomised control trials, laboratory studies, in-vitro studies, in-vivo studies and ex-vivo studies were included. Data from the studies were collected using the data extraction form, and all the relevant information was summarized. Five of 24 studies were done on animals, four on humans, five on models, and ten on various cells. Ten of 24 studies demonstrated the harmful effects of millimetre waves. Results are ambivalent, and no association is found between particular frequency and impact on tissue, animals or humans. Pathophysiological effects observed in most studies were mild, reversible, and limited to the cellular level. Available evidence reported temperature rise after millimetre wave exposure, which was within safety limits. Any biological impact on a cellular level noticed due to radiation's thermal effects were insignificant and did not affect the organ level. However, only a few studies have mentioned non-thermal impact, but those effects should not be overlooked. Clinical trials on a large population and for a longer duration are required to establish the safety of millimetre waves before deploying a 5G network worldwide.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"168 - 176"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48843563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estimation of stress amongst the parents of neonates admitted to neonatal intensive care unit 新生儿重症监护室新生儿父母压力的评估
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_132_22
Pragati Sisodia, H. Khan, N. Shukla, Richa Rathoria, Ekansh Rathoria, Utkarsh Bansal, Ram Shukla
Introduction: The admission of the baby to the neonatal intensive care unit (NICU) can be a stressful predicament for parents. This study aims to evaluate parental stress levels and the factors impacting them. Materials and Methods: This cross-sectional study was conducted in the NICU of a tertiary care centre for 3 months. Data were collected using a questionnaire consisting of demographic characteristics of parents, neonates and Parental Stressor Scale: NICU (PSS: NICU) to measure parental stress. The data were analysed using descriptive statistics and an independent t-test. Results: P ≤ 0.05 was considered statistically significant. Most of the parents reported medium stress levels (3–3.9). The mean total parental stress score of parents was 3.31 (0.36). Amongst the PSS: NICU subscales, the NICU sight and sound caused maximum stress to the parents (mean = 3.35 [0.48]) followed by the relationship with the baby and parental role (mean = 3.34 [0.44]). Mothers felt more stressed as compared to fathers (mean = 3.60 [0.23] vs. 3.08 [0.28]; P < 0.05). Conclusion: Higher parental stress levels were seen in lower age group (18–25 years), less than high school education, unemployed and previous history of neonatal death, outborn deliveries, pre-term (gestational age <37 weeks), birth weight <1500 g, longer duration of respiratory support (>3 days), intubated with ventilatory support, not started on feeds and not given kangaroo mother care. Parents of NICU-admitted neonates are under significant stress, and there is a necessity to provide family-centred care.
引言:新生儿重症监护室(NICU)的婴儿入院对父母来说可能是一个压力重重的困境。本研究旨在评估父母的压力水平及其影响因素。材料和方法:这项横断面研究在一家三级护理中心的新生儿重症监护室进行,为期3个月。使用由父母、新生儿的人口统计学特征和父母压力源量表(PSS:NICU)组成的问卷收集数据,以测量父母的压力。使用描述性统计和独立t检验对数据进行分析。结果:P≤0.05具有统计学意义。大多数父母报告中等压力水平(3-3.9)。父母的平均总压力得分为3.31(0.36)。在PSS:NICU分量表中,新生儿重症监护室的视觉和声音给父母带来了最大的压力(平均值=3.35[0.48]),其次是与婴儿的关系和父母角色(平均值3.34[0.44])。与父亲相比,母亲感到压力更大(平均值3.60[0.23]对3.08[0.28];P<0.05),失业和既往新生儿死亡史、分娩史、足月前(胎龄3天)、插管通气支持史、未开始进食史和未给予袋鼠妈妈护理史。新生儿重症监护室新生儿的父母承受着巨大的压力,有必要提供以家庭为中心的护理。
{"title":"Estimation of stress amongst the parents of neonates admitted to neonatal intensive care unit","authors":"Pragati Sisodia, H. Khan, N. Shukla, Richa Rathoria, Ekansh Rathoria, Utkarsh Bansal, Ram Shukla","doi":"10.4103/aihb.aihb_132_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_132_22","url":null,"abstract":"Introduction: The admission of the baby to the neonatal intensive care unit (NICU) can be a stressful predicament for parents. This study aims to evaluate parental stress levels and the factors impacting them. Materials and Methods: This cross-sectional study was conducted in the NICU of a tertiary care centre for 3 months. Data were collected using a questionnaire consisting of demographic characteristics of parents, neonates and Parental Stressor Scale: NICU (PSS: NICU) to measure parental stress. The data were analysed using descriptive statistics and an independent t-test. Results: P ≤ 0.05 was considered statistically significant. Most of the parents reported medium stress levels (3–3.9). The mean total parental stress score of parents was 3.31 (0.36). Amongst the PSS: NICU subscales, the NICU sight and sound caused maximum stress to the parents (mean = 3.35 [0.48]) followed by the relationship with the baby and parental role (mean = 3.34 [0.44]). Mothers felt more stressed as compared to fathers (mean = 3.60 [0.23] vs. 3.08 [0.28]; P < 0.05). Conclusion: Higher parental stress levels were seen in lower age group (18–25 years), less than high school education, unemployed and previous history of neonatal death, outborn deliveries, pre-term (gestational age <37 weeks), birth weight <1500 g, longer duration of respiratory support (>3 days), intubated with ventilatory support, not started on feeds and not given kangaroo mother care. Parents of NICU-admitted neonates are under significant stress, and there is a necessity to provide family-centred care.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"205 - 210"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43868070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Comparative evaluation of quality of obturation and instrumentation time using different file systems in deciduous molars: A randomised clinical trial 一项随机临床试验:不同文件系统对乳牙封闭质量和内固定时间的比较评价
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_22_22
Foram Patel, Megha Patel, Rohan Bhatt, Kaushal Joshi
Introduction: Multiple systems are available for chemo-mechanical preparation during pulpectomy, but an evolution of the exclusive paediatric rotary single file system has opened new doors in paediatric endodontics. The aim was primarily to compare the quality of obturation and instrumentation time and secondarily to report pain perception between manual files and rotary file systems in deciduous molars. Materials and Methods: Pulpectomy was performed in 60 carious mandibular primary molars indicated for pulpectomy in children aged 4–8 years after considering the selection criteria. These teeth were divided randomly into three groups of 20 each, wherein canals were prepared using Hand K files in Group 1, HeroShaper Rotary File System in Group 2 and Kedo S Square single paediatric rotary file in Group 3. The quality of obturation was assessed using intraoral radiographs, and instrumentation time was recorded in seconds using a stopwatch. Pain during instrumentation was assessed using Wong Baker's FACES Pain Scale. Collected data were subjected to analysis using the Chi-square test, one-way ANOVA and Honestly Significant Difference post hoc test. Results: Mean instrumentation time was least for the Kedo-S Square file system (57.47 ± 9.26), followed by the HeroShaper group (99.6 ± 23.62), and maximum time was recorded for Hand files (255.99 ± 46.20), and this difference was statistically significant (P = 0.00), whereas there was no significant difference regarding the quality of obturation and pain perception between the three groups. Conclusion: As the Kedo S Square system showed the fastest canal preparation, it can be recommended for pulpectomy procedures in primary teeth because the length of appointment is directly proportional to the behaviour of the child.
引言:牙髓切除术期间有多种系统可用于化学机械制备,但独家儿科旋转单文件系统的发展为儿科牙髓病学打开了新的大门。目的主要是比较闭孔质量和器械时间,其次报告乳牙手动锉和旋转锉系统之间的疼痛感知。材料和方法:在考虑选择标准后,对60颗适合4-8岁儿童牙髓切除术的下颌龋性第一磨牙进行了牙髓切除术。将这些牙齿随机分为三组,每组20颗,其中使用第1组中的Hand K锉、第2组中的HeroShaper旋转锉系统和第3组中的Kedo S Square单儿科旋转锉制备牙管。使用口腔内射线照片评估充填质量,并使用秒表记录仪器时间(以秒为单位)。使用Wong Baker的FACES疼痛量表评估器械过程中的疼痛。使用卡方检验、单因素方差分析和诚实显著性差异事后检验对收集的数据进行分析。结果:Kedo-S Square文件系统的平均器械时间最少(57.47±9.26),其次是HeroShaper组(99.6±23.62),Hand文件记录的最长器械时间为(255.99±46.20),这一差异具有统计学意义(P=0.00),而三组之间在闭孔质量和疼痛感知方面没有显著差异。结论:由于Kedo S Square系统显示出最快的牙髓管预备,因此可以推荐用于乳牙的牙髓切除术,因为预约时间与儿童的行为直接成正比。
{"title":"Comparative evaluation of quality of obturation and instrumentation time using different file systems in deciduous molars: A randomised clinical trial","authors":"Foram Patel, Megha Patel, Rohan Bhatt, Kaushal Joshi","doi":"10.4103/aihb.aihb_22_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_22_22","url":null,"abstract":"Introduction: Multiple systems are available for chemo-mechanical preparation during pulpectomy, but an evolution of the exclusive paediatric rotary single file system has opened new doors in paediatric endodontics. The aim was primarily to compare the quality of obturation and instrumentation time and secondarily to report pain perception between manual files and rotary file systems in deciduous molars. Materials and Methods: Pulpectomy was performed in 60 carious mandibular primary molars indicated for pulpectomy in children aged 4–8 years after considering the selection criteria. These teeth were divided randomly into three groups of 20 each, wherein canals were prepared using Hand K files in Group 1, HeroShaper Rotary File System in Group 2 and Kedo S Square single paediatric rotary file in Group 3. The quality of obturation was assessed using intraoral radiographs, and instrumentation time was recorded in seconds using a stopwatch. Pain during instrumentation was assessed using Wong Baker's FACES Pain Scale. Collected data were subjected to analysis using the Chi-square test, one-way ANOVA and Honestly Significant Difference post hoc test. Results: Mean instrumentation time was least for the Kedo-S Square file system (57.47 ± 9.26), followed by the HeroShaper group (99.6 ± 23.62), and maximum time was recorded for Hand files (255.99 ± 46.20), and this difference was statistically significant (P = 0.00), whereas there was no significant difference regarding the quality of obturation and pain perception between the three groups. Conclusion: As the Kedo S Square system showed the fastest canal preparation, it can be recommended for pulpectomy procedures in primary teeth because the length of appointment is directly proportional to the behaviour of the child.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"211 - 217"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49025306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of online learning during the COVID-19 pandemic on medical students and faculty members: A cross-sectional study from Majmaah University, Saudi Arabia COVID-19大流行期间在线学习对医学生和教职员工的影响:来自沙特阿拉伯Majmaah大学的横断面研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_49_22
M. L. Lateef Junaid, W. Sami, Hamad Aldhafiri, Jehad Alabdulmonyem, Abdulkarim Alenazi, A. Kaseb
Introduction: During the ongoing COVID-19 pandemic, all prospective of life have been affected by the situation. As a result of which, many universities adopted the online way of teaching instead of the traditional classroom teaching or by blending both together. This study was carried out with the objective to assess the perception of teachers and students regarding classes taken online versus those taken in the classroom. Materials and Methods: A descriptive cross-sectional study was carried out among students and faculty members of the medical college at Majmaah University, KSA, from October 2020 to April 2021. Results: The study found that the majority of teachers have disagreed (91%) that online classes were more effective than classroom mode, and regarding the overall perception of teachers for classes taken online and in the classroom, 62% of teachers agreed that online classes were better than classroom mode, whereas 38% disagreed; 61% of students agreed that online classes were better than classroom mode, and 39% disagreed. Conclusion: Educational institutions should be ready to handle pandemic-like situations without disrupting educational activities and to achieve this, appropriate training of the faculty members and students should be carried out to make online teaching effective and also to minimise any associated disturbing factors.
简介:在持续的新冠肺炎大流行期间,所有的生活前景都受到了这种情况的影响。因此,许多大学采用了在线教学方式,而不是传统的课堂教学,或者将两者融合在一起。这项研究的目的是评估教师和学生对在线课程和课堂课程的看法。材料和方法:2020年10月至2021年4月,在KSA Majmah大学医学院的学生和教职员工中进行了一项描述性横断面研究。结果:研究发现,大多数教师不同意(91%)网课比课堂模式更有效,关于教师对在线和课堂上课的总体看法,62%的教师同意网课比教室模式更好,而38%的教师不同意;61%的学生同意网课比课堂模式更好,39%的学生不同意。结论:教育机构应准备好在不干扰教育活动的情况下应对类似疫情的情况,为此,应对教职员工和学生进行适当的培训,以使在线教学有效,并将任何相关的干扰因素降至最低。
{"title":"Impact of online learning during the COVID-19 pandemic on medical students and faculty members: A cross-sectional study from Majmaah University, Saudi Arabia","authors":"M. L. Lateef Junaid, W. Sami, Hamad Aldhafiri, Jehad Alabdulmonyem, Abdulkarim Alenazi, A. Kaseb","doi":"10.4103/aihb.aihb_49_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_49_22","url":null,"abstract":"Introduction: During the ongoing COVID-19 pandemic, all prospective of life have been affected by the situation. As a result of which, many universities adopted the online way of teaching instead of the traditional classroom teaching or by blending both together. This study was carried out with the objective to assess the perception of teachers and students regarding classes taken online versus those taken in the classroom. Materials and Methods: A descriptive cross-sectional study was carried out among students and faculty members of the medical college at Majmaah University, KSA, from October 2020 to April 2021. Results: The study found that the majority of teachers have disagreed (91%) that online classes were more effective than classroom mode, and regarding the overall perception of teachers for classes taken online and in the classroom, 62% of teachers agreed that online classes were better than classroom mode, whereas 38% disagreed; 61% of students agreed that online classes were better than classroom mode, and 39% disagreed. Conclusion: Educational institutions should be ready to handle pandemic-like situations without disrupting educational activities and to achieve this, appropriate training of the faculty members and students should be carried out to make online teaching effective and also to minimise any associated disturbing factors.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"218 - 222"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46063878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of total antioxidant capacity in patients with bladder cancer and its correlation with the results of pathology 癌症患者总抗氧化能力的测定及其与病理结果的相关性
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_68_22
Z. Tolou_Ghamari, H. Mazdak
Introduction: The accumulative consequence of all antioxidants that exist in the blood and body fluids is called total antioxidant capacity (TAOC). The major objective of this investigation is to determine the correlation between TAOC and pathology results in patients with non-muscle invasive bladder cancer (NMIBC). Materials and Methods: Based on the cross-sectional method, 35 patients with NMIBC and 35 controls (healthy characters) were studied. Biochemical and haematological variables were achieved and noted for each individual. Two blood samples (n = 5 ml) from each patient were obtained and analysed using Trolox standard immunoassay kit. Three groups were made according to the pathology results. The significance level was set at P ≤ 0.05. Results: There were not any significant differences (P = 0.12) between the mean age of patients and controls (60.7 vs. 59.5 years old) correspondingly. The mean value of TAOC (μmol/L) was significantly (P = 0.005) lower in patients when compared to controls (24.5 μmol/L vs. 94 μmol/L), respectively. In patients with NMIBC, sodium, magnesium, calcium, albumin, MCH, MCHC, VHCO3, haemoglobin, haematocrit and lymph were lower than the normal range. Blood sugar, creatinine, prothrombin time and white blood cells were higher than the normal range. The mean TAOC was as follows: papillary cell carcinoma (26.3 μmol/L), radical cystectomy (19 μmol/L) and high-grade bladder cancer (15.9 μmol/L). Conclusion: As deregulation of reactive oxygen species and antioxidant defence is two important components, in this study, there was high variation in TAOC according to pathology results. Combing individual TAOC and pathology results might be able to contribute to the advanced management of NMIBC. Further studies in this direction seem to be advantageous.
简介:血液和体液中存在的所有抗氧化剂的累积结果称为总抗氧化能力(TAOC)。本研究的主要目的是确定TAOC与非肌肉浸润性膀胱癌(NMIBC)患者病理结果的相关性。材料与方法:采用横断面法对35例NMIBC患者和35例健康对照进行研究。获得并记录了每个个体的生化和血液学变量。每位患者取两份血样(n = 5 ml),使用Trolox标准免疫测定试剂盒进行分析。根据病理结果分为三组。显著性水平为P≤0.05。结果:两组患者的平均年龄(60.7岁vs. 59.5岁)比较,差异无统计学意义(P = 0.12)。患者TAOC (μmol/L)平均值(24.5 μmol/L vs. 94 μmol/L)显著低于对照组(P = 0.005)。NMIBC患者钠、镁、钙、白蛋白、MCH、MCHC、VHCO3、血红蛋白、红细胞压积和淋巴均低于正常范围。血糖、肌酐、凝血酶原时间、白细胞均高于正常范围。平均TAOC分别为:乳头状细胞癌(26.3 μmol/L)、根治性膀胱切除术(19 μmol/L)和高级别膀胱癌(15.9 μmol/L)。结论:由于活性氧的解除和抗氧化防御是两个重要组成部分,在本研究中,根据病理结果,TAOC有很大的变化。结合个体TAOC和病理结果可能有助于NMIBC的先进治疗。在这个方向上进一步研究似乎是有利的。
{"title":"Determination of total antioxidant capacity in patients with bladder cancer and its correlation with the results of pathology","authors":"Z. Tolou_Ghamari, H. Mazdak","doi":"10.4103/aihb.aihb_68_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_68_22","url":null,"abstract":"Introduction: The accumulative consequence of all antioxidants that exist in the blood and body fluids is called total antioxidant capacity (TAOC). The major objective of this investigation is to determine the correlation between TAOC and pathology results in patients with non-muscle invasive bladder cancer (NMIBC). Materials and Methods: Based on the cross-sectional method, 35 patients with NMIBC and 35 controls (healthy characters) were studied. Biochemical and haematological variables were achieved and noted for each individual. Two blood samples (n = 5 ml) from each patient were obtained and analysed using Trolox standard immunoassay kit. Three groups were made according to the pathology results. The significance level was set at P ≤ 0.05. Results: There were not any significant differences (P = 0.12) between the mean age of patients and controls (60.7 vs. 59.5 years old) correspondingly. The mean value of TAOC (μmol/L) was significantly (P = 0.005) lower in patients when compared to controls (24.5 μmol/L vs. 94 μmol/L), respectively. In patients with NMIBC, sodium, magnesium, calcium, albumin, MCH, MCHC, VHCO3, haemoglobin, haematocrit and lymph were lower than the normal range. Blood sugar, creatinine, prothrombin time and white blood cells were higher than the normal range. The mean TAOC was as follows: papillary cell carcinoma (26.3 μmol/L), radical cystectomy (19 μmol/L) and high-grade bladder cancer (15.9 μmol/L). Conclusion: As deregulation of reactive oxygen species and antioxidant defence is two important components, in this study, there was high variation in TAOC according to pathology results. Combing individual TAOC and pathology results might be able to contribute to the advanced management of NMIBC. Further studies in this direction seem to be advantageous.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"223 - 226"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47294213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of magnetic resonance imaging in colorectal diseases 磁共振成像在结直肠疾病中的作用
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_126_21
Vaibhav Khare, R. Rastogi, Amit Mishra, N. Verma, V. Bhandari, Ashutosh Kumar Singh, Sunil Kumar, Vijai Pratap, Nitishkumar Yeshlawat, Aditi Khare
Introduction: Modern society is experiencing a noticeable increase in the prevalence of colorectal disease due to a variety of causes, including changes in lifestyle and dietary habits as well as increased use of a variety of chemicals in the form of preservatives flavouring agents and stabilisers. Colorectal diseases are a cause of significant morbidity, hence, often gaining attention early in the disease. Although colonoscopy is a standard, the preferred tool for diagnosis and at times for management is often uncomfortable for the patient besides being incomplete in a significant percentage of patients. Hence, magnetic resonance imaging (MRI) has gained importance in recent years for the evaluation of colorectal diseases not only due to its non-invasive nature but also due to lack of radiation, a boon over computed tomography, which is considered a standard imaging tool. Hence, we planned this pilot study to evaluate the role of MRI in our tertiary care, medical college and hospital. Materials and Methods: Twenty patients with signs and symptoms of colorectal disease were evaluated by 1.5T MRI followed by conventional, flexible, fibreoptic colonoscopy on the same day after obtaining approval from the Institutional Ethics Committee and after obtaining written informed consent using strict criteria. Appropriate statistical methods and tools were used to evaluate the results from the data of MRI and colonoscopy that was recorded in predesigned pro forma and compared with the final tissue diagnosis. Results: Both the median and mean age of patients in our study were 40–45 years with male predominance (M:F = 4:1). Altered bowel habits followed by bleeding per rectum were the most common presentations seen in more than 90% of patients. Both MRI and colonoscopy misdiagnosed the lesions as malignant with higher errors by MRI. MRI had high sensitivity and negative predictive value in diagnosing a malignant lesion with moderate accuracy approaching 70%. In contrast, colonoscopy was superior in specificity and positive predictive value with higher accuracy of 80%. Conclusion: Although conventional colonoscopy is the standard tool for the diagnosis of colorectal diseases, several shortcomings of colonoscopy, including its invasive nature, several contraindications and risk of complications coupled with low yield limits, are used as a screening tool. However, non-invasive and radiation-free MRI with its high sensitivity and negative predictive value for malignant lesions make it preferable as a screening tool in the evaluation of colorectal diseases.
导语:由于各种原因,包括生活方式和饮食习惯的改变,以及以防腐剂、调味剂和稳定剂的形式增加使用各种化学物质,现代社会正在经历结肠直肠疾病患病率的显著增加。结直肠疾病是一个重要的发病率的原因,因此,往往在疾病早期引起注意。虽然结肠镜检查是一种标准,但作为诊断和治疗的首选工具,除了在很大比例的患者中是不完整的之外,通常对患者来说是不舒服的。因此,磁共振成像(MRI)近年来在评估结直肠疾病方面变得越来越重要,这不仅是因为它的非侵入性,还因为它缺乏辐射,这比计算机断层扫描(被认为是一种标准的成像工具)更有优势。因此,我们计划了这项试点研究,以评估MRI在我们的三级保健,医学院和医院的作用。材料与方法:20例有结直肠疾病体征和症状的患者,经机构伦理委员会批准,并按照严格的标准获得书面知情同意后,于当天行1.5T MRI后常规、柔性、纤维结肠镜检查。采用适当的统计方法和工具对预先设计的形式记录的MRI和结肠镜检查数据的结果进行评估,并与最终的组织诊断进行比较。结果:本研究患者中位年龄和平均年龄均为40-45岁,以男性为主(M:F = 4:1)。在90%以上的患者中,排便习惯改变后直肠出血是最常见的表现。MRI和结肠镜检查均误诊为恶性病变,MRI误诊率较高。MRI对恶性病变的诊断具有较高的敏感性和阴性预测值,中等准确率接近70%。相比之下,结肠镜检查在特异性和阳性预测值方面具有优势,准确率高达80%。结论:虽然常规结肠镜检查是诊断结直肠疾病的标准工具,但结肠镜检查存在侵入性、禁忌症多、并发症风险大、筛查率低等缺点。然而,无创、无辐射的MRI对恶性病变具有较高的敏感性和阴性的预测价值,使其成为评价结直肠疾病的首选筛查工具。
{"title":"Role of magnetic resonance imaging in colorectal diseases","authors":"Vaibhav Khare, R. Rastogi, Amit Mishra, N. Verma, V. Bhandari, Ashutosh Kumar Singh, Sunil Kumar, Vijai Pratap, Nitishkumar Yeshlawat, Aditi Khare","doi":"10.4103/aihb.aihb_126_21","DOIUrl":"https://doi.org/10.4103/aihb.aihb_126_21","url":null,"abstract":"Introduction: Modern society is experiencing a noticeable increase in the prevalence of colorectal disease due to a variety of causes, including changes in lifestyle and dietary habits as well as increased use of a variety of chemicals in the form of preservatives flavouring agents and stabilisers. Colorectal diseases are a cause of significant morbidity, hence, often gaining attention early in the disease. Although colonoscopy is a standard, the preferred tool for diagnosis and at times for management is often uncomfortable for the patient besides being incomplete in a significant percentage of patients. Hence, magnetic resonance imaging (MRI) has gained importance in recent years for the evaluation of colorectal diseases not only due to its non-invasive nature but also due to lack of radiation, a boon over computed tomography, which is considered a standard imaging tool. Hence, we planned this pilot study to evaluate the role of MRI in our tertiary care, medical college and hospital. Materials and Methods: Twenty patients with signs and symptoms of colorectal disease were evaluated by 1.5T MRI followed by conventional, flexible, fibreoptic colonoscopy on the same day after obtaining approval from the Institutional Ethics Committee and after obtaining written informed consent using strict criteria. Appropriate statistical methods and tools were used to evaluate the results from the data of MRI and colonoscopy that was recorded in predesigned pro forma and compared with the final tissue diagnosis. Results: Both the median and mean age of patients in our study were 40–45 years with male predominance (M:F = 4:1). Altered bowel habits followed by bleeding per rectum were the most common presentations seen in more than 90% of patients. Both MRI and colonoscopy misdiagnosed the lesions as malignant with higher errors by MRI. MRI had high sensitivity and negative predictive value in diagnosing a malignant lesion with moderate accuracy approaching 70%. In contrast, colonoscopy was superior in specificity and positive predictive value with higher accuracy of 80%. Conclusion: Although conventional colonoscopy is the standard tool for the diagnosis of colorectal diseases, several shortcomings of colonoscopy, including its invasive nature, several contraindications and risk of complications coupled with low yield limits, are used as a screening tool. However, non-invasive and radiation-free MRI with its high sensitivity and negative predictive value for malignant lesions make it preferable as a screening tool in the evaluation of colorectal diseases.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"181 - 186"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48460038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraperitoneal instillation of levobupivacaine plus dexmedetomidine versus ropivacaine plus dexmedetomidine for post-operative analgesia in patients undergoing laparoscopic cholecystectomy 左布比卡因加右美托咪定与罗哌卡因加右美托咪定腹膜内滴注用于腹腔镜胆囊切除术后镇痛
IF 0.4 Q4 BIOLOGY Pub Date : 2023-04-01 DOI: 10.4103/aihb.aihb_123_21
Rekha Roat, Hemant Jingar, R. Verma, Mamta Damor
Introduction: Laparoscopic procedures have many advantages over open procedures, such as less haemorrhage, better cosmetic results, less post-operative pain and shorter recovery time, leading to a shorter hospital stay and less expenditure. Hence, the present study was undertaken for comparing the effect of intraperitoneal installation of levobupivacaine (L-B) plus dexmedetomidine versus ropivacaine plus dexmedetomidine for post-operative analgesia in patients undergoing laparoscopic cholecystectomy (LC). Materials and Methods: This was a prospective randomized study conducted in our hospital on 60 American Society of Anaesthesiologists grade I or II patients of either sex, aged 18–55 years, scheduled to undergo LC surgery under general anaesthesia. All patients were randomly divided into two groups of 30 each: Group 1: Patients were given 20 ml of 0.5% L-B plus 0.25-μg/kg dexmedetomidine intraperitoneally after gallbladder removal, and Group 2: Patients were given 20 ml of 0.5% ropivacaine plus 0.25-μg/kg dexmedetomidine intraperitoneally after gallbladder removal. Post-operatively, the patients were assessed for pain utilizing a visual analogue scale (VAS). VAS was graded on a scale of 0–10. VAS was recorded at 0, 1, 8, 12 and 24 h post-operatively and compared. Results: Mean time to first analgesic requirement among patients of Group 1 and Group 2 was 365.1 min and 297.2 min, respectively, which shows a statistically significant longer post-operative analgesic effect in Group 1 patients. While comparing VAS at different time intervals in between the two study groups, all the readings were comparable. The difference was found to be non-significant in the two groups (P > 0.05). Nausea and vomiting were seen in two patients in Group 1 and three patients in Group 2. Complications were noted in <10% of the patients in both groups. Conclusion: Intraperitoneal instillation of local anaesthetic solution in LC provides effective post-operative analgesia, and analgesia provided by L-B plus dexmedetomidine is better than ropivacaine plus dexmedetomidine.
腹腔镜手术比开放手术有许多优点,如出血少,美容效果好,术后疼痛少,恢复时间短,住院时间短,费用少。因此,本研究旨在比较左布比卡因(L-B)联合右美托咪定与罗哌卡因联合右美托咪定在腹腔镜胆囊切除术(LC)患者术后镇痛中的效果。材料与方法:本研究是在我院进行的一项前瞻性随机研究,对象为60例在全身麻醉下行LC手术的美国麻醉学会I级或II级患者,年龄18-55岁,男女均可。所有患者随机分为两组,每组30人,第1组:胆囊切除后腹腔给予0.5% L-B 20 ml + 0.25 μg/kg右美托咪定;第2组:胆囊切除后腹腔给予0.5%罗哌卡因20 ml + 0.25 μg/kg右美托咪定。术后,使用视觉模拟评分(VAS)评估患者的疼痛。VAS评分为0-10分。分别于术后0、1、8、12、24 h进行VAS记录并比较。结果:第1组和第2组患者到达首次需要镇痛药的平均时间分别为365.1 min和297.2 min,第1组患者术后镇痛效果较长,差异有统计学意义。在比较两个研究组在不同时间间隔的VAS时,所有读数都具有可比性。两组比较差异无统计学意义(P < 0.05)。1组2例恶心呕吐,2组3例恶心呕吐。两组患者并发症发生率均<10%。结论:LC腹腔注射局麻液能有效地实现术后镇痛,且L-B联合右美托咪定的镇痛效果优于罗哌卡因联合右美托咪定。
{"title":"Intraperitoneal instillation of levobupivacaine plus dexmedetomidine versus ropivacaine plus dexmedetomidine for post-operative analgesia in patients undergoing laparoscopic cholecystectomy","authors":"Rekha Roat, Hemant Jingar, R. Verma, Mamta Damor","doi":"10.4103/aihb.aihb_123_21","DOIUrl":"https://doi.org/10.4103/aihb.aihb_123_21","url":null,"abstract":"Introduction: Laparoscopic procedures have many advantages over open procedures, such as less haemorrhage, better cosmetic results, less post-operative pain and shorter recovery time, leading to a shorter hospital stay and less expenditure. Hence, the present study was undertaken for comparing the effect of intraperitoneal installation of levobupivacaine (L-B) plus dexmedetomidine versus ropivacaine plus dexmedetomidine for post-operative analgesia in patients undergoing laparoscopic cholecystectomy (LC). Materials and Methods: This was a prospective randomized study conducted in our hospital on 60 American Society of Anaesthesiologists grade I or II patients of either sex, aged 18–55 years, scheduled to undergo LC surgery under general anaesthesia. All patients were randomly divided into two groups of 30 each: Group 1: Patients were given 20 ml of 0.5% L-B plus 0.25-μg/kg dexmedetomidine intraperitoneally after gallbladder removal, and Group 2: Patients were given 20 ml of 0.5% ropivacaine plus 0.25-μg/kg dexmedetomidine intraperitoneally after gallbladder removal. Post-operatively, the patients were assessed for pain utilizing a visual analogue scale (VAS). VAS was graded on a scale of 0–10. VAS was recorded at 0, 1, 8, 12 and 24 h post-operatively and compared. Results: Mean time to first analgesic requirement among patients of Group 1 and Group 2 was 365.1 min and 297.2 min, respectively, which shows a statistically significant longer post-operative analgesic effect in Group 1 patients. While comparing VAS at different time intervals in between the two study groups, all the readings were comparable. The difference was found to be non-significant in the two groups (P > 0.05). Nausea and vomiting were seen in two patients in Group 1 and three patients in Group 2. Complications were noted in <10% of the patients in both groups. Conclusion: Intraperitoneal instillation of local anaesthetic solution in LC provides effective post-operative analgesia, and analgesia provided by L-B plus dexmedetomidine is better than ropivacaine plus dexmedetomidine.","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"177 - 180"},"PeriodicalIF":0.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47059516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Advances in Human Biology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1