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Audit of quality indicators of cytology: An institutional study 细胞学质量指标审计:一项机构研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_99_22
Snigdha Sinha, Subhashis Das, R. Kalyani
Introduction: At present, clinical laboratories play a vital role in diagnosing and providing quality treatment. Various quality control (QC) and quality assurance (QA), including the pre-analytical and post-analytical variables, were taken into consideration for the internal quality indicators in the department of cytopathology of our institution. The aim of this study is to evaluate the importance of QC and QA parameters in the routine work of the cytopathology laboratory. Materials and Methods: This is a prospective cross-sectional study of 24 months duration. A total of 15,520 were evaluated for quality parameters. Results: A total of 15,520 cytology cases were evaluated. The cyto-histo correlation, non-conformities, TAT, Repeats and redo's, critical value, quality of staining and revised report rate were noted and identified with relevant statistical analysis. Conclusion: Routine QC and QA will ensure better diagnostic services and promote accreditation of laboratory activities.
引言:目前,临床实验室在诊断和提供优质治疗方面发挥着至关重要的作用。我们机构细胞病理科的内部质量指标考虑了各种质量控制(QC)和质量保证(QA),包括分析前和分析后的变量。本研究的目的是评估QC和QA参数在细胞病理学实验室日常工作中的重要性。材料和方法:这是一项为期24个月的前瞻性横断面研究。共评估了15520个质量参数。结果:共对15520例细胞学病例进行了评估。记录细胞-组织相关性、不符合项、TAT、重复次数和重做次数、临界值、染色质量和修订报告率,并通过相关统计分析进行鉴定。结论:常规QC和QA将确保更好的诊断服务,并促进实验室活动的认证。
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引用次数: 0
Comparative evaluation of diagnostic efficacy of cell block versus aspiration cytology 细胞阻滞与抽吸细胞学诊断效果的比较评价
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_98_22
Nikhil Chaudhary, Subhashis Das, Snigdha Sinha
Introduction: Fine-needle aspiration cytology (FNAC) has certain disadvantages despite being the most commonly used procedure in the initial diagnosis of any swelling. In such cases, a cell block (CB) study can be a valuable adjunct to smears for establishing a more definitive cytopathological diagnosis. Therefore, this study was conducted to evaluate the efficacy of CB with FNAC and to compare the findings of the CB and FNAC with histopathology as the gold standard. Materials and Methods: The study was conducted in the department of pathology at our institute. All the cystic/solid lesions sent for fine-needle aspiration, which yielded sufficient material for the CB, were studied along with detailed clinical history. Results: Out of 66 cases of FNAC and CB, 35 cases were sent for histopathology. The mean age of the patients was 41.36 years, and female patients were more in number (73%). Benign lesions (71.4%) were more than malignant ones (29.6%). The CB section had more thyroid lesions (31%). The diagnostic accuracy of FNAC was found to be 94.28%, while that of CB was 97.14%. Conclusion: Although FNAC is the first line of investigation for mass lesions, and still, to make the best possible use of an aspirate, smears should be used together with CB preparation to provide the best possible morphological and histological diagnosis.
引言:细针抽吸细胞学(FNAC)是任何肿胀的初步诊断中最常用的方法,但它有一定的缺点。在这种情况下,细胞块(CB)研究可以作为涂片检查的一种有价值的辅助手段,用于建立更明确的细胞病理学诊断。因此,本研究旨在评估CB与FNAC的疗效,并将CB和FNAC的结果与组织病理学作为金标准进行比较。材料与方法:本研究在我所病理科进行。对所有被送去进行细针抽吸的囊性/实体性病变进行了研究,这些病变为CB提供了足够的材料,并伴有详细的临床病史。结果:在66例FNAC和CB中,35例被送去进行组织病理学检查。患者平均年龄为41.36岁,女性患者较多(73%)。良性病变(71.4%)多于恶性病变(29.6%),CB切片甲状腺病变较多(31%)。FNAC的诊断准确率为94.28%,CB的诊断准确度为97.14%。
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引用次数: 0
Comparison of the effects of midazolam, dexamethasone, ondansetron and propofol on the prevention and control of opioid-induced pruritus after spinal anaesthesia with bupivacaine combined with fentanyl in femoral fracture surgery 咪唑安定、地塞米松、昂丹司琼和丙泊酚预防和控制股骨头骨折术中布比卡因复合芬太尼脊麻后阿片类药物性瘙痒的效果比较
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_45_22
H. Modir, Esmail Moshiri, Mehran Azami, Amirreza Modir
Introduction: The present study set out to compare the effects of midazolam, dexamethasone, ondansetron and propofol on the prevention and control of opioid-induced pruritus after spinal anaesthesia with bupivacaine and fentanyl as adjuvants in femoral fracture surgery. Materials and Methods: This double-blind clinical trial study was conducted on 136 patients who were scheduled for orthopaedic surgery in Valiasr Hospital of Arak. The patients were randomly divided into four groups (ondansetron, midazolam, dexamethasone and propofol) with a block randomisation pattern. Blood pressure, heart rate, oxygen saturation, the incidence of pruritus, nausea, vomiting and sedation level were monitored and recorded intraoperatively and postoperatively in recovery and every 2 h until 12 h postoperatively. Data were then analysed with SPSS 20. Results: From 10 min to 60 min, blood pressure was lower in the midazolam group, while it was lower in the propofol group from 60 min to 105 min. In general, blood pressure in the midazolam group was lower than that in the other groups (P = 0.001). Furthermore, pruritus was observed less in the midazolam group than in the other groups (P < 0.05). Sedation level was higher in the midazolam group than in the other groups (P < 0.05). Conclusion: Midazolam reduced pruritus and increased sedation in patients. On the other hand, a decrease in blood pressure was observed in the midazolam group, which did not require any special treatment. According to the results of the present study, after midazolam, propofol and dexamethasone, and finally ondansetron, respectively, were effective in controlling pruritus after spinal anaesthesia, but the efficacy and effectiveness of midazolam were higher than that in the other groups. As such, this drug is recommended to be used in such procedures. Of course, it should be mentioned that the final decision depends on the patients' physical conditions and the anaesthesiologist's discretion.
前言:本研究旨在比较咪唑安定、地塞米松、昂丹司琼和丙泊酚在股骨干骨折手术中以布比卡因和芬太尼为佐剂预防和控制脊麻后阿片类药物引起的瘙痒的效果。材料和方法:这项双盲临床试验研究对136名在阿拉克瓦利亚尔医院接受整形外科手术的患者进行。患者随机分为四组(昂丹司琼、咪达唑仑、地塞米松和丙泊酚),分组随机。术中、术后恢复期以及术后每2小时至12小时监测和记录血压、心率、血氧饱和度、瘙痒发生率、恶心、呕吐和镇静水平。然后用SPSS 20对数据进行分析。结果:咪达唑仑组在10分钟至60分钟内血压较低,丙泊酚组在60分钟至105分钟内血压低于其他组(P=0.001),咪达唑仑组瘙痒发生率低于其他组(P<0.05),镇静水平高于其他组(P<0.05)。另一方面,咪达唑仑组的血压下降,不需要任何特殊治疗。根据本研究的结果,在咪唑安定、丙泊酚和地塞米松以及最后的昂丹司琼之后,分别对控制脊髓麻醉后的瘙痒有效,但咪唑安定的疗效和有效性高于其他组。因此,建议在此类手术中使用这种药物。当然,应该提到的是,最终决定取决于患者的身体状况和麻醉师的判断。
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引用次数: 0
Assessment of total and soluble fluoride content in commercial dentifrices and mouthwashes available in the Indian market: An in vitro study 印度市场上可买到的商用牙膏和漱口水中总氟和可溶性氟含量的评估:一项体外研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_63_22
Akanksha Keswani, P. Thakkar, A. Mansata, Jill Shah, Anil Patel, Kena Shah
Introduction: Dental caries is the most common dental problem across the globe. Due to the increase in the use of refined sugars and lack of fluoride exposure, dental caries is becoming a serious issue for public health. The present study was conducted to determine the total fluoride (TF) concentration and soluble fluoride concentration in different dentifrices and mouthwashes available in the Indian market. Materials and Methods: Ion-specific electrode and fluoride ion metre were used to determine the soluble fluoride, as well as the TF concentration of seven dentifrices and five mouthwashes, and the findings were recorded in particle per million of fluoride. Descriptive statistic was used, and mean ± standard deviation of TF and soluble fluoride content of dentifrices and mouthwashes were reported. Results: Nine samples contained sodium fluoride and three samples contained sodium monofluorophosphate Na MFP as the fluoride compound. The TF and soluble fluoride levels showed variations from the fluoride concentration mentioned on the packaging. Conclusions: This study found that the concentration of total soluble fluoride and TF was lower than the fluoride level mentioned on the packaging.
简介:龋齿是全球最常见的牙齿问题。由于精制糖使用的增加和氟化物暴露的减少,龋齿正成为公众健康的一个严重问题。本研究旨在测定印度市场上不同牙膏和漱口水中的总氟化物(TF)浓度和可溶性氟化物浓度。材料和方法:用离子比电极和氟离子计测定7种牙膏和5种漱口水的可溶性氟化物以及TF浓度,并以百万分之一氟化物的颗粒数记录。采用描述性统计,报告牙膏和漱口水中TF和可溶性氟含量的平均值±标准差。结果:9个样品含有氟化钠,3个样品含有一氟磷酸钠-MFP作为氟化物。TF和可溶性氟化物水平与包装上提到的氟化物浓度不同。结论:本研究发现,总可溶性氟化物和TF的浓度低于包装上提到的氟化物水平。
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引用次数: 0
Subjective assessment of bonded fixed lingual retainers: A questionnaire survey 粘接固定舌固位器的主观评价:问卷调查
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_122_21
N. Kulkarni, V. Shah
Aims: This study aimed to assess the patients' subjective assessment of bonded fixed lingual retainers after completion of active orthodontic treatment. Objective: A questionnaire comprising 11 questions evaluated the patients' experience with bonded fixed lingual retainer. Materials and Methods: The content was validated by a group of seven experienced orthodontists. The questionnaire survey was run using Google Forms, responded by 45 (50.6%) males and 44 (49.4%) females between the ages ranging from 19 to 42 years. Their responses were rated on a Visual Analogue Scale as applicable. Cronbach's alpha test was utilised for assessing the reliability, and the Chi-square test was used for the quantitative variables. Results: 33.7% of individuals were most comfortable, and 2.2% had severe discomfort during retainer placement. 6.6% of individuals had severe difficulty maintaining oral hygiene in the upper arch and 4.4% in lower teeth and gums, respectively. 2.2% had severe difficulty in speech. 85.4% had no tongue ulceration. 37.1% of respondents had a very good overall experience with fixed bonded lingual retainer, 59.5% had mild problems and only 1.1% had severe problems with a very bad experience. Conclusions: The study concluded that the overall experience of respondents with fixed lingual bonded retainer had mild problems. It was comfortable for most of the patients in maintaining oral hygiene with mild difficulty in speech and chewing. The cause of failure of the retainer was mainly due to bond failure or broken wire in the retainer.
目的:本研究旨在评估患者在完成主动正畸治疗后对粘接固定舌固位器的主观评价。目的:通过11个问题的问卷调查,评价粘接固定舌固位器患者的使用体验。材料和方法:内容由七名经验丰富的正畸医师进行验证。问卷调查采用谷歌表格,年龄19 ~ 42岁,男性45人(50.6%),女性44人(49.4%)。根据适用的视觉模拟量表对他们的反应进行评分。信度采用Cronbach’s alpha检验,定量变量采用卡方检验。结果:33.7%的人在固位器放置过程中感到最舒适,2.2%的人在固位器放置过程中感到严重不适。6.6%的人在上牙弓和4.4%的人在下牙和牙龈有严重的口腔卫生困难。2.2%有严重的言语困难。85.4%患者舌部无溃疡。37.1%的受访者对固定粘接舌固位器的整体体验非常好,59.5%的受访者有轻微的问题,只有1.1%的受访者有严重的问题,体验非常差。结论:本研究的结论是,受访者使用固定舌结合固位器的整体体验有轻微的问题。大部分患者保持口腔卫生舒适,言语和咀嚼有轻微困难。固位器失效的原因主要是固位器粘结失效或断丝。
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引用次数: 0
To evaluate and compare the microtensile bond strength of dentine with the use of two-step and one-step adhesives: An ex vivo study 评估和比较两步和一步粘接剂对牙本质微拉伸结合强度的影响:一项离体研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_10_22
Niharika Patel, Aruna Kanaparthy, Rosaiah Kanaparthy
Introduction: In the evolving world of adhesive dentistry, there has always been controversy regarding the adhesive system to be used for superior clinical performance, and clinicians often find themselves in a dilemma with so many products on the market. It, therefore, becomes necessary to know the various properties of different adhesive systems and their comparative analysis. Materials and Methods: Thirty, intact, non-carious and unrestored human mandibular premolars, which were extracted for orthodontic purposes were taken for the study. Teeth were divided into two groups A and B having 15 teeth in each group. The inclusion criteria were that the teeth should be non-carious, unrestored and should have been extracted for orthodontic purposes. Excluded teeth were those with caries, restorations, attrition, cracks and developmental defects. The teeth were embedded in resin, occlusal enamel was removed and the teeth were restored with composite resin using two different approaches for bonding. Teeth of Group A were bonded using single bond and teeth of Group B were bonded using Clearfil S3 Bond and were then sectioned to produce beams with an approximate cross-sectional area of 4 mm × 4 mm. These sections were mounted to a custom acrylic jig and subjected to microtensile bond strength testing using a universal testing machine with a cross head speed of 1 mm/min and stressed to de-bonding of the composite resin from the tooth. Results: Data were subjected to statistical analysis and evaluated using the analysis of variance test and Tukey's test which showed that single bond or two-step adhesive showed higher microtensile bond strength to dentine. Conclusion: The two-step single bond performed better than the one-step Clearfil S3, but the result was statistically non-significant.
导言:在不断发展的粘接牙科世界中,一直存在着关于粘接剂系统用于卓越临床性能的争议,临床医生经常发现自己在市场上有这么多产品的困境。因此,有必要了解不同胶粘剂体系的各种性能并对其进行比较分析。材料与方法:选取30颗完整、无龋、未修复的用于正畸的人下颌前磨牙进行研究。牙齿分为A组和B组,每组15颗牙齿。纳入标准为无龋齿、未修复、已拔牙用于正畸。排除有龋、修复、磨损、裂纹和发育缺陷的牙齿。用树脂包埋牙齿,去除牙釉质,用复合树脂修复牙齿,采用两种不同的方法进行粘接。A组牙采用单键粘接,B组牙采用Clearfil S3键粘接,然后将其切割成横截面积约为4mm × 4mm的梁。这些部分安装在定制的丙烯酸夹具上,并使用十字头速度为1毫米/分钟的万能试验机进行微拉伸粘结强度测试,并强调复合树脂与牙齿的分离。结果:对数据进行统计分析,并采用方差分析检验和Tukey’s检验进行评价,结果表明单步粘接剂或两步粘接剂对牙本质的微拉伸结合强度更高。结论:两步单键优于一步clearfils3,但差异无统计学意义。
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引用次数: 0
Clinical evaluation and parental and child satisfaction with restoration of primary teeth using zirconia and stainless steel crowns: A randomised clinical study 使用氧化锆和不锈钢冠修复乳牙的临床评价及家长和儿童满意度:一项随机临床研究
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_43_22
Rohan Bhatt, D. Shah, Megha Patel, Srushti Khurana
Introduction: Full-coronal restoration is the choice of treatment for restoring pulpally treated tooth or tooth with multiple surface involvement. In paediatric dentistry, semi-permanent stainless steel crowns (SSCs) are considered gold standard, but with increasing need of aesthetics, zirconia crowns have started gaining importance. Hence, this study was conducted to evaluate the clinical performance of SSCs and zirconia crowns and to compare the child satisfaction and parental ratings of impact of treatment using these preformed crowns. Materials and Methodology: This study was a part of randomised controlled trial performed on 60 children of 4–8 years old. The primary molars were cemented with either SSCs or zirconia crowns and were evaluated clinically at baseline, 6-month and 12-month follow-up for crown retention, crown fracture, gingival and debris index, wear, marginal integrity and recurrent caries. The trials also evaluated parental satisfaction and child satisfaction based on five-point Likert scale at the end of 12-month follow-up. The data were analysed using Chi-square test for categorical data and independent sample t-test for quantitative data. Results: Both the crowns were 100% retentive at 12-month follow-up. Fair debris score and mild gingivitis were reported in 3% with SSC at 6–12 months. One zirconia crown fractured at 12 months. Fifty-four per cent of parents in zirconia and 57% in SSC stated that the crowns improved masticatory function. Children reported a mean Likert score of 3.0 for SSC and 4.89 for zirconia which was highly significant. Conclusion: Both the crowns increased the overall health of crowned tooth and were fully retentive for the studied duration. However, zirconia crowns were more gingival friendly and had an edge over SSC in terms of aesthetics.
简介:全冠状面修复是修复牙髓治疗或多面受累牙齿的首选治疗方法。在儿科牙科中,半永久性不锈钢牙冠(ssc)被认为是金标准,但随着对美学需求的增加,氧化锆牙冠开始获得重视。因此,本研究旨在评估ssc和氧化锆冠的临床性能,并比较儿童满意度和家长对使用这些预制冠治疗影响的评分。材料与方法:本研究为随机对照试验的一部分,对60名4-8岁儿童进行研究。用ssc或氧化锆冠固接初生磨牙,并在基线、6个月和12个月的随访中临床评估冠固位、冠骨折、牙龈和碎片指数、磨损、边缘完整性和复发龋病。在12个月的随访结束时,试验还评估了基于五点李克特量表的父母满意度和儿童满意度。分类资料采用卡方检验,定量资料采用独立样本t检验。结果:随访12个月,冠体固位率均为100%。3%的SSC患者在6-12个月时报告了公平的碎片评分和轻度牙龈炎。1例12个月时氧化锆冠断裂。氧化锆组54%的家长和SSC组57%的家长表示,牙冠改善了孩子的咀嚼功能。儿童报告SSC的平均李克特评分为3.0,氧化锆的平均李克特评分为4.89,这是非常显著的。结论:两种冠体均提高了冠牙的整体健康,并在研究时间内保持完整。然而,氧化锆冠对牙龈更友好,在美学方面比SSC有优势。
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引用次数: 0
Childhood tuberculosis - An emerging health challenge for Bangladesh 儿童结核病——孟加拉国面临的新健康挑战
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_171_22
K. Chowdhury, Mainul Haque
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引用次数: 0
Obesity and overweight: A global public health issue 肥胖和超重:一个全球公共卫生问题
IF 0.4 Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_106_22
Mushtahid Salam, R. Yousuf, Mushtahid Salam, Mainul Haque
{"title":"Obesity and overweight: A global public health issue","authors":"Mushtahid Salam, R. Yousuf, Mushtahid Salam, Mainul Haque","doi":"10.4103/aihb.aihb_106_22","DOIUrl":"https://doi.org/10.4103/aihb.aihb_106_22","url":null,"abstract":"","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"13 1","pages":"154 - 156"},"PeriodicalIF":0.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44837669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Obesity, cardiometabolic syndrome and bariatric surgery 肥胖,心脏代谢综合征和减肥手术
Q4 BIOLOGY Pub Date : 2023-01-01 DOI: 10.4103/aihb.aihb_109_23
Mainul Haque, Susmita Sinha, Mahendra Narwaria
{"title":"Obesity, cardiometabolic syndrome and bariatric surgery","authors":"Mainul Haque, Susmita Sinha, Mahendra Narwaria","doi":"10.4103/aihb.aihb_109_23","DOIUrl":"https://doi.org/10.4103/aihb.aihb_109_23","url":null,"abstract":"","PeriodicalId":7341,"journal":{"name":"Advances in Human Biology","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136207161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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