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Safety of same-day discharge knee arthroplasty surgery: a retrospective analysis of observational data from the hospital episode statistics dataset for England 当日出院膝关节置换术的安全性:对英国医院事件统计数据集观察性数据的回顾性分析
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-17 DOI: 10.1007/s00402-025-06090-6
Oliver Adebayo, Tim Briggs, William Gray

Introduction

Same-day discharge total knee arthroplasty (TKA), although still only performed regularly in a few hospital trusts in England, is becoming more common. However, evidence is needed to show that same-day discharge TKA is safe. We aimed to use a nationwide administrative data source to investigate the safety of same-day discharge TKA.

Materials and methods

We extracted data from the Hospital Episodes Statistics database for the six years from 1st April 2017 to 31st March 2023. Patients undergoing primary elective TKA aged ≥ 17 years were included. The primary outcome was emergency readmission within 30 days of surgery. Average treatment effect on the treated (ATET) propensity score matching was used to compare outcomes for those operated on as same-day discharge and those with an overnight stay after adjusting for covariates.

Results

Data was available for 398,771 patients, of whom 3,718 (0.9%) were discharge on the same day that they were admitted. Rates of same-day discharge increased from 0.5% in 2017/18 to 1.6% in 2022/23. There was a significantly increased odds of all-cause 30-day readmission in same-day discharge patients across the entire six years (ATET 0.018, 95% confidence interval 0.011 to 0.025) but not for 2022/23 (ATET 0.009, 95% confidence interval (CI) -0.001 to 0.020). Complication rates (identified during index stay or 30-day emergency readmission) were significantly lower with same-day discharge across the six years (ATET − 0.008, 95% CI -0.012 to -0.003) and for 2022/23 only (ATET − 0.015, 95% CI -0.022 to -0.008). One year mortality rates (2022/23 data excluded) were not significantly different between the two groups (ATET 0.001, 95% CI -0.002 to 0.003). Comparing trusts with > 5% and 0% same-day discharge rates for 2022/23 outcomes were either no different or better in trust with a SDD rate > 5%.

Conclusions

Same-day discharge TKA is safe and outcomes have improved as the practice has become more common. Same-day discharge TKA may help to improve patient outcomes and increase the efficiency of the procedure.

当日出院全膝关节置换术(TKA),虽然仍然只在英格兰的几家医院定期进行,但正变得越来越普遍。然而,需要证据表明当天出院TKA是安全的。我们的目的是使用一个全国性的管理数据源来调查当日出院TKA的安全性。材料和方法:我们从医院事件统计数据库中提取2017年4月1日至2023年3月31日6年的数据。纳入年龄≥17岁的原发性选择性TKA患者。主要结局是手术30天内急诊再入院。在调整协变量后,使用平均治疗效果对被治疗者(ATET)倾向评分匹配来比较当日出院和过夜住院患者的结果。结果:398,771例患者获得资料,其中3718例(0.9%)患者在入院当日出院。当日出院率从2017/18年的0.5%上升到2022/23年的1.6%。在整个6年中,当日出院患者的全因30天再入院的几率显著增加(ATET为0.018,95%可信区间为0.011至0.025),但在2022/23年度无显著增加(ATET为0.009,95%可信区间(CI)为0.001至0.020)。并发症发生率(在指数住院或30天紧急再入院期间确定)在6年内同一天出院时显著降低(ATET -0.008, 95% CI -0.012至-0.003),仅在2022/23年(ATET - 0.015, 95% CI -0.022至-0.008)。两组一年死亡率(排除2022/23年数据)无显著差异(ATET 0.001, 95% CI -0.002 ~ 0.003)。比较2022/23年结果的同一天出院率为> 5%和0%的信托,SDD率为> 5%的信托要么没有差异,要么更好。结论:当天出院TKA是安全的,并且随着这种做法变得越来越普遍,结果有所改善。当日出院TKA可能有助于改善患者的治疗效果,提高手术效率。
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引用次数: 0
A comparative analysis of ChatGPT and Google in providing quality and clinical relevance of responses to patients’ frequently asked questions on robotic-assisted total knee arthroplasty ChatGPT和谷歌对机器人辅助全膝关节置换术患者常见问题回答的质量和临床相关性的比较分析
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-17 DOI: 10.1007/s00402-025-06085-3
Mahmud Aydin, Furkan Aral, Mustafa Fatih Dasci, Serkan Surucu, Mahir Mahirogullari, Mustafa Citak

Introduction

The purpose of this study was to identify the most frequent questions a patient might encounter in an internet search about robotic-assisted total knee arthroplasty (RATKA), and to identify and categorize the answers to these questions to assess the suitability of Chat Generative Pre-Trained Transformer (ChatGPT) and Google search engine as an online health information source for patients.

Methods

The 20 most frequently asked questions (FAQs) were identified by entering the search term “Robot-Assisted Total Knee Replacement” into both Google Search and ChatGPT-4. For Google, a clean search was performed, and the 20 FAQs were extracted from the “People also ask” section. For ChatGPT-4, a specific prompt was used to generate the 20 most frequently asked questions. All identified questions, along with the corresponding answers and cited references, were systematically recorded. A modified version of the Rothwell system was used to categorize questions into 10 subtopics. Each reference was categorized into the following groups: commercial, academic, medical practice, single surgeon personal, or social media. The questions and sources obtained from ChatGPT and Google were compared using Fisher’s exact test.

Results

The percentage distribution of questions by category between Google and ChatGPT was as follows: indications/management (15% vs. 25%), technical details (35% vs. 30%), evaluation of surgery (0% vs. 0%), risks/complications (5% vs. 5%), restrictions (10% vs. 0%), specific activities (15% vs. 5%), timeline of recovery (10% vs. 20%), pain (0% vs. 5%), longevity (0% vs. 0%), and cost (10% vs. 10%). Answers to questions were more frequently sourced from academic websites in ChatGPT compared to Google (70% vs. 20%; p-value = 0.0025).

Conclusion

ChatGPT offers a promising alternative to traditional search engines for patient education, particularly in the context of preparing for RATKA. Compared to Google, ChatGPT provided significantly fewer references to commercial content and offered responses that were more aligned with academic sources.

Level of evidence

Level IV, Survey study Internet sources.

本研究的目的是确定患者在互联网上搜索机器人辅助全膝关节置换术(RATKA)时可能遇到的最常见问题,并对这些问题的答案进行识别和分类,以评估聊天生成预训练转换器(ChatGPT)和谷歌搜索引擎作为患者在线健康信息源的适用性。方法:通过在谷歌search和ChatGPT-4中输入搜索词“机器人辅助全膝关节置换术”,确定20个最常见的问题。对于谷歌,执行干净的搜索,并从“People also ask”部分提取20个faq。对于ChatGPT-4,使用一个特定的提示来生成20个最常被问到的问题。所有确定的问题,以及相应的答案和引用的参考文献,都被系统地记录下来。一个改良版的Rothwell系统被用来将问题分成10个小主题。每个参考文献被分为以下几组:商业、学术、医疗实践、单个外科医生个人或社交媒体。从ChatGPT和谷歌获得的问题和来源使用Fisher精确检验进行比较。结果:谷歌和ChatGPT之间按类别划分的问题百分比分布如下:指征/管理(15%对25%)、技术细节(35%对30%)、手术评估(0%对0%)、风险/并发症(5%对5%)、限制(10%对0%)、特定活动(15%对5%)、恢复时间(10%对20%)、疼痛(0%对5%)、寿命(0%对0%)和费用(10%对10%)。与谷歌相比,ChatGPT中的问题答案更频繁地来自学术网站(70% vs. 20%; p值= 0.0025)。结论:ChatGPT为患者教育提供了一个有希望的替代传统搜索引擎,特别是在准备RATKA的背景下。与b谷歌相比,ChatGPT提供的商业内容参考要少得多,并且提供的回答更符合学术来源。证据等级:四级,调查研究网络资源。
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引用次数: 0
Correction: Scapho-metacarpal dual mobility prosthesis for TMC-1 joint salvage: technical insights 纠正:用于TMC-1关节修复的舟-掌骨双活动假体:技术见解。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-17 DOI: 10.1007/s00402-025-06050-0
Julia Glaser, Martin Aman, Thomas Krohn, Joris Duerinckx, Benjamin Panzram, Leila Harhaus
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引用次数: 0
Return to sport after arthrodesis and implant arthroplasty for hallux rigidus : a systematic review 拇僵直关节融合术和人工关节置换术后恢复运动:系统回顾。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06082-6
Thomas Stumpner, Stephan Obermayr, George Abdel-Nour, Simon Recheis, Michael Stephan Gruber, Reinhold Ortmaier

Background

Painful, degenerative stiffening of the first metatarsophalangeal (MTP-1) joint, as seen in hallux rigidus, is common among athletic individuals due to repetitive microtrauma. While arthrodesis of the MTP-1 joint is considered the gold standard for advanced degeneration, the resulting loss of motion may impair sports and recreational activities. Implant arthroplasty, by preserving joint mobility, may offer functional benefits for active patients.

Methods

In accordance with PRISMA guidelines, a comprehensive literature search was conducted using PubMed, LIVIVO, the Cochrane Controlled Trials Library, Science Direct, CINHAL and Scopus. Studies reporting on sports function after MTP-1 arthrodesis or implant arthroplasty for degenerative arthritis were included. Fifteen studies with 1,103 procedures met the inclusion criteria. Sport-specific outcomes and functional scores were extracted and analyzed.

Results

Data on sports function following MTP-1 arthrodesis and implant arthroplasty are heterogeneous, limiting direct comparison. Arthrodesis studies reported return-to-sport rates of up to 100%, with a shift from high-impact to in-line activities. Implant arthroplasty showed similar return-to-sport rates, with potential short-term functional benefits. However, long-term superiority could not be demonstrated, and higher complication rates must be considered.

Conclusion

MTP-1 arthrodesis remains a reliable treatment for end-stage hallux rigidus, offering satisfactory long-term sports function. Implant arthroplasty may provide short-term advantages in active patients but carries a higher risk of complications and has not shown superior long-term outcomes in sports participation.

背景:第一跖趾(MTP-1)关节疼痛,退行性僵硬,如拇僵直,在运动个体中由于重复性微创伤是常见的。虽然MTP-1关节融合术被认为是晚期退变的金标准,但由此导致的运动能力丧失可能会影响运动和娱乐活动。人工关节置换术,通过保持关节的灵活性,可以为活动患者提供功能上的好处。方法:按照PRISMA指南,综合检索PubMed、LIVIVO、Cochrane对照试验图书馆、Science Direct、CINHAL和Scopus等文献。研究报告了MTP-1关节融合术或假体关节置换术治疗退行性关节炎后的运动功能。15项研究1103项手术符合纳入标准。提取并分析运动特异性结果和功能评分。结果:MTP-1关节融合术和人工关节置换术后的运动功能数据存在差异,限制了直接比较。关节融合术研究报告,从高冲击运动到直线运动的恢复率高达100%。人工关节置换术显示出相似的恢复运动率,具有潜在的短期功能益处。然而,长期的优势无法证明,必须考虑更高的并发症发生率。结论:MTP-1关节融合术仍然是治疗终末期拇僵硬的可靠方法,可提供满意的长期运动功能。人工关节置换术可能为活跃患者提供短期优势,但存在较高的并发症风险,并且在运动参与方面没有显示出优越的长期结果。
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引用次数: 0
Impact of temperature and humidity on periprosthetic joint infections following total knee arthroplasty: a 12-year study in a Mediterranean climate 温度和湿度对全膝关节置换术后假体周围关节感染的影响:一项为期12年的地中海气候研究。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06081-7
Volkan Buyukarslan, Aliekber Yapar, Dilek Yapar, Firat Dogruoz, Ozkan Kose, Mustafa Citak

Introduction

This study aimed to examine the influence of temperature, humidity, and seasonal trends on periprosthetic joint infections (PJI) following total knee arthroplasty (TKA) over a 12-year period in a Mediterranean climate.

Methods

A retrospective cohort study was conducted on 5520 patients who underwent TKA between January 1, 2011, and December 31, 2022. Data were collected on patient demographics, surgical details, and PJI incidence, which were defined by Musculoskeletal Infection Society (MSIS) criteria. Meteorological data on daily average temperature and relative humidity were obtained for the same period. Statistical analyses were performed to assess the associations between PJI incidence, seasonal variations, temperature, and humidity.

Results

The overall incidence of PJI was 1.4%, with a significant downward trend over the 12 years (β coefficient= -0.115; p = 0.011). The highest PJI incidence (2%) was observed in winter, but no significant association was found between PJI incidence and seasonal variations (p = 0.080). The temperature range ≤ 5 °C had the highest PJI rate (6.7%), while the 20–25 °C range showed the lowest rate (0.4%). No significant effect of humidity levels on PJI incidence was identified (p = 0.174).

Conclusion

The study demonstrates a general decline in PJI incidence over time and suggests that colder temperatures are associated with higher PJI rates, with ≤ 5 °C posing the most significant risk. However, humidity and seasonal variations did not significantly influence infection rates. These findings underscore the importance of considering environmental factors like temperature when planning TKA procedures, particularly in regions with Mediterranean climates.

Level of evidence

Level III, Retrospective cohort study.

本研究旨在研究地中海气候下12年期间全膝关节置换术(TKA)后温度、湿度和季节趋势对假体周围关节感染(PJI)的影响。方法:对2011年1月1日至2022年12月31日期间5520例接受TKA的患者进行回顾性队列研究。根据肌肉骨骼感染学会(MSIS)的标准,收集了患者人口统计学、手术细节和PJI发生率的数据。同期的日平均气温和相对湿度的气象资料。统计分析评估PJI发病率、季节变化、温度和湿度之间的关系。结果:PJI总发病率为1.4%,12年间呈显著下降趋势(β系数= -0.115;p = 0.011)。冬季PJI发病率最高(2%),但PJI发病率与季节变化无显著相关性(p = 0.080)。温度≤5℃时PJI率最高(6.7%),20 ~ 25℃时最低(0.4%)。湿度水平对PJI发病率无显著影响(p = 0.174)。结论:该研究表明PJI发病率随着时间的推移普遍下降,并表明较冷的温度与较高的PJI发病率相关,≤5°C的风险最大。然而,湿度和季节变化对感染率没有显著影响。这些发现强调了在规划TKA程序时考虑温度等环境因素的重要性,特别是在地中海气候地区。证据等级:III级,回顾性队列研究。
{"title":"Impact of temperature and humidity on periprosthetic joint infections following total knee arthroplasty: a 12-year study in a Mediterranean climate","authors":"Volkan Buyukarslan,&nbsp;Aliekber Yapar,&nbsp;Dilek Yapar,&nbsp;Firat Dogruoz,&nbsp;Ozkan Kose,&nbsp;Mustafa Citak","doi":"10.1007/s00402-025-06081-7","DOIUrl":"10.1007/s00402-025-06081-7","url":null,"abstract":"<div><h3>Introduction</h3><p>This study aimed to examine the influence of temperature, humidity, and seasonal trends on periprosthetic joint infections (PJI) following total knee arthroplasty (TKA) over a 12-year period in a Mediterranean climate.</p><h3>Methods</h3><p>A retrospective cohort study was conducted on 5520 patients who underwent TKA between January 1, 2011, and December 31, 2022. Data were collected on patient demographics, surgical details, and PJI incidence, which were defined by Musculoskeletal Infection Society (MSIS) criteria. Meteorological data on daily average temperature and relative humidity were obtained for the same period. Statistical analyses were performed to assess the associations between PJI incidence, seasonal variations, temperature, and humidity.</p><h3>Results</h3><p>The overall incidence of PJI was 1.4%, with a significant downward trend over the 12 years (β coefficient= -0.115; <i>p</i> = 0.011). The highest PJI incidence (2%) was observed in winter, but no significant association was found between PJI incidence and seasonal variations (<i>p</i> = 0.080). The temperature range ≤ 5 °C had the highest PJI rate (6.7%), while the 20–25 °C range showed the lowest rate (0.4%). No significant effect of humidity levels on PJI incidence was identified (<i>p</i> = 0.174).</p><h3>Conclusion</h3><p>The study demonstrates a general decline in PJI incidence over time and suggests that colder temperatures are associated with higher PJI rates, with ≤ 5 °C posing the most significant risk. However, humidity and seasonal variations did not significantly influence infection rates. These findings underscore the importance of considering environmental factors like temperature when planning TKA procedures, particularly in regions with Mediterranean climates.</p><h3>Level of evidence</h3><p>Level III, Retrospective cohort study.</p></div>","PeriodicalId":8326,"journal":{"name":"Archives of Orthopaedic and Trauma Surgery","volume":"145 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anticholinergic burden and postoperative mortality in older adults with hip fracture: a real-world observational study 老年髋部骨折患者的抗胆碱能负荷和术后死亡率:一项真实世界的观察性研究。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06091-5
Alejandro Valcuende-Rosique, Elisa García-Tercero, Ana Valcuende-Rosique, Magdalena Linge Martin, Francisco Tomas-Aguirre, Ana Navalon-Bono, José Viña Ribes, Francisco José Tarazona-Santabalbina
AbstractSection Introduction

Anticholinergic burden is common in older adults and has been associated with adverse outcomes such as cognitive impairment and functional decline. Its long-term effect on surgical recovery after hip fracture, however, remains unclear. This study aimed to evaluate the association between anticholinergic burden at hospital admission and postoperative outcomes, including mortality, functional recovery, and readmissions, in older adults undergoing hip fracture surgery.

AbstractSection Methods

This retrospective observational study included patients aged ≥ 70 years who underwent surgical treatment for hip fracture between January 2017 and December 2018. Anticholinergic burden was quantified using the Anticholinergic Cognitive Burden (ACB) scale based on pre-admission medications, and patients were classified into two groups: low burden (ACB 0–2) and high burden (ACB ≥ 3). The primary outcome was 5-year all-cause mortality. Secondary outcomes included in-hospital complications, readmissions, and ambulatory recovery at 30 days and 6 months.

AbstractSection Results

646 patients were included in the study; 206 (31.9%) had a high anticholinergic burden. Compared to those with low burden, high burden patients had greater comorbidity (Charlson Index 3.1 vs. 2.6, p = 0.005), poorer baseline function (Barthel Index 65.7 vs. 79.1, p < 0.001), and more frequent severe polypharmacy (≥ 10 drugs: 45.1% vs. 7.4%, p < 0.001). They experienced more in-hospital complications (56.8% vs. 47.5%, p = 0.028), and major complications (56.3% vs. 44.8%, p = 0.006). Functional recovery was significantly reduced, with fewer patients ambulatory at 30 days (59.7% vs. 72.8%, p = 0.002) and at 6 months (71.5% vs. 83.0%, p = 0.002). Readmissions were more frequent (2.2 vs. 1.7 per patient, p = 0.015). Five-year mortality was higher in the high burden group (71.8% vs. 47.0%, p < 0.001), with an adjusted HR of 1.56 (95% CI: 1.22–2.00). Median follow-up time was 1.425 days (IQR 450–1825).

AbstractSection Conclusions

High anticholinergic burden at admission is independently associated with increased long-term mortality, complications, readmissions, and poorer functional recovery after hip fracture surgery in older adults.

AbstractSection Graphical abstract
摘要抗胆碱能负荷在老年人中很常见,并与认知障碍和功能下降等不良结局相关。然而,其对髋部骨折术后恢复的长期影响尚不清楚。本研究旨在评估住院时抗胆碱能负荷与老年人髋部骨折术后结局(包括死亡率、功能恢复和再入院)之间的关系。【摘要】【章节方法】本回顾性观察研究纳入2017年1月至2018年12月期间接受髋部骨折手术治疗的年龄≥70岁的患者。采用基于入院前用药的抗胆碱能认知负担量表(ACB)量化抗胆碱能负担,并将患者分为低负担组(ACB 0 ~ 2)和高负担组(ACB≥3)。主要结局为5年全因死亡率。次要结局包括住院并发症、再入院和30天和6个月的门诊恢复。【摘要】结果646例患者纳入研究;206例(31.9%)抗胆碱能负荷较高。与低负担患者相比,高负担患者的合病发生率更高(Charlson指数3.1 vs. 2.6, p = 0.005),基线功能较差(Barthel指数65.7 vs. 79.1, p < 0.001),严重多重用药发生率更高(≥10种药物:45.1% vs. 7.4%, p < 0.001)。住院并发症(56.8%比47.5%,p = 0.028)和主要并发症(56.3%比44.8%,p = 0.006)较多。功能恢复明显降低,30天(59.7% vs. 72.8%, p = 0.002)和6个月(71.5% vs. 83.0%, p = 0.002)时可走动的患者减少。再入院频率更高(2.2 vs 1.7 /例,p = 0.015)。高负担组的5年死亡率更高(71.8% vs. 47.0%, p < 0.001),调整后风险比为1.56 (95% CI: 1.22-2.00)。中位随访时间为1.425天(IQR 450-1825)。【摘要】结论:老年人髋部骨折术后入院时较高的抗胆碱能负荷与长期死亡率、并发症、再入院率和较差的功能恢复独立相关。摘要部分图形摘要
{"title":"Anticholinergic burden and postoperative mortality in older adults with hip fracture: a real-world observational study","authors":"Alejandro Valcuende-Rosique,&nbsp;Elisa García-Tercero,&nbsp;Ana Valcuende-Rosique,&nbsp;Magdalena Linge Martin,&nbsp;Francisco Tomas-Aguirre,&nbsp;Ana Navalon-Bono,&nbsp;José Viña Ribes,&nbsp;Francisco José Tarazona-Santabalbina","doi":"10.1007/s00402-025-06091-5","DOIUrl":"10.1007/s00402-025-06091-5","url":null,"abstract":"<div>\u0000 \u0000 <span>AbstractSection</span>\u0000 Introduction\u0000 <p>Anticholinergic burden is common in older adults and has been associated with adverse outcomes such as cognitive impairment and functional decline. Its long-term effect on surgical recovery after hip fracture, however, remains unclear. This study aimed to evaluate the association between anticholinergic burden at hospital admission and postoperative outcomes, including mortality, functional recovery, and readmissions, in older adults undergoing hip fracture surgery.</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Methods\u0000 <p>This retrospective observational study included patients aged ≥ 70 years who underwent surgical treatment for hip fracture between January 2017 and December 2018. Anticholinergic burden was quantified using the Anticholinergic Cognitive Burden (ACB) scale based on pre-admission medications, and patients were classified into two groups: low burden (ACB 0–2) and high burden (ACB ≥ 3). The primary outcome was 5-year all-cause mortality. Secondary outcomes included in-hospital complications, readmissions, and ambulatory recovery at 30 days and 6 months.</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Results\u0000 <p>646 patients were included in the study; 206 (31.9%) had a high anticholinergic burden. Compared to those with low burden, high burden patients had greater comorbidity (Charlson Index 3.1 vs. 2.6, <i>p</i> = 0.005), poorer baseline function (Barthel Index 65.7 vs. 79.1, <i>p</i> &lt; 0.001), and more frequent severe polypharmacy (≥ 10 drugs: 45.1% vs. 7.4%, <i>p</i> &lt; 0.001). They experienced more in-hospital complications (56.8% vs. 47.5%, <i>p</i> = 0.028), and major complications (56.3% vs. 44.8%, <i>p</i> = 0.006). Functional recovery was significantly reduced, with fewer patients ambulatory at 30 days (59.7% vs. 72.8%, <i>p</i> = 0.002) and at 6 months (71.5% vs. 83.0%, <i>p</i> = 0.002). Readmissions were more frequent (2.2 vs. 1.7 per patient, <i>p</i> = 0.015). Five-year mortality was higher in the high burden group (71.8% vs. 47.0%, <i>p</i> &lt; 0.001), with an adjusted HR of 1.56 (95% CI: 1.22–2.00). Median follow-up time was 1.425 days (IQR 450–1825).</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Conclusions\u0000 <p>High anticholinergic burden at admission is independently associated with increased long-term mortality, complications, readmissions, and poorer functional recovery after hip fracture surgery in older adults.</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Graphical abstract\u0000 <div><figure><div><div><picture><source><img></source></picture></div></div></figure></div>\u0000 \u0000 </div>","PeriodicalId":8326,"journal":{"name":"Archives of Orthopaedic and Trauma Surgery","volume":"145 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of age, sex, height, ethnicity, and femoral bowing on the anatomical fitting of the LCP distal femur plate 年龄、性别、身高、种族和股骨弯曲对LCP股骨远端钢板解剖拟合的影响。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06079-1
Beat Schmutz, Minh Tri Phan, Jeremy Pople, Bertha Ching Wai Lam, Eden Schoofs, Jacelle Warren, Jaimi Conlon, Hiroaki Minehara, Kevin Tetsworth, Michael Schuetz

Purpose

Lateral locking-plate fixation is commonly used for distal femur fractures. Pre-contoured plates attempt to match the bony anatomy of the target patient population. However, plate fit is highly variable due to inter-subject morphological differences. If plate misfit is not recognised and addressed, axial malalignment may arise. This study evaluates the effects of age, sex, height, ethnicity, and femoral bowing on the anatomical fit of a distal femur plate.

Methods

Unilateral 3D models of 80 (40 male, 40 female) Caucasian and 79 (34 male, 45 female) Vietnamese femora were utilised. Both cohorts consisted of young (< 65 years) and old (≥ 65 years) subjects, with 40 young and 40 old Caucasian, and 36 young and 43 old Vietnamese. The plate undersurfaces of 9-, 11- and 13-hole LCP Distal Femur plate 3D models were positioned on bone models and anatomical fitting was assessed through application of developed clinical criteria.

Results

Satisfactory plate conformity was achieved from plate head up to hole 6, with most measurement locations fitting 52–100% of bones from both ethnicities. There was tendency towards proximal plate misfit from hole 8 onwards with 0–41% fit achieved in this region, and mean distances of 11.6 mm and 16.3 mm being observed at the proximal plate tip for Caucasians and Vietnamese respectively (p ≤ 0.017). Patient sex, height, ethnicity, and femoral bowing all had significant impacts on fit, while the effect of age was limited. Sex and ethnicity related height differences would suggest that patient height and femoral bowing are the main variables affecting fit.

Conclusions

The observed proximal plate misfit for both Caucasians and Vietnamese suggests LCP Distal Femur plates may exhibit less anatomical conformity than generally assumed. Where plates are used as a reduction tool, pre-operative templating of the intact contralateral femur may help identify plate misfit.

目的:外侧锁定钢板固定是治疗股骨远端骨折的常用方法。预轮廓钢板试图匹配目标患者人群的骨骼解剖结构。然而,由于受试者之间的形态差异,钢板配合是高度可变的。如果板不匹配没有被识别和处理,轴向失调可能会出现。本研究评估了年龄、性别、身高、种族和股骨弯曲对股骨远端钢板解剖配合的影响。方法:采用80例白种人(男40例,女40例)和79例越南股骨(男34例,女45例)单侧三维模型。结果:从钢板头到6号孔的钢板一致性令人满意,大多数测量位置与来自两个种族的52-100%的骨头吻合。从第8孔开始,近端板有不匹配的趋势,该区域的拟合率为0 ~ 41%,白种人和越南人近端板尖端的平均距离分别为11.6 mm和16.3 mm (p≤0.017)。患者的性别、身高、种族和股骨弯曲均对适合度有显著影响,而年龄的影响有限。性别和种族相关的身高差异表明患者身高和股骨弯曲是影响契合度的主要变量。结论:观察到的白种人和越南人的近端钢板不匹配表明LCP股骨远端钢板可能表现出比通常认为的更少的解剖一致性。当钢板被用作复位工具时,术前对侧完整股骨的模板可以帮助识别钢板错位。
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引用次数: 0
Inflammatory bowel disease and its association with increased PJI risk in total hip arthroplasty: the role of steroid use 炎性肠病及其与全髋关节置换术中PJI风险增加的关联:类固醇使用的作用
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06094-2
Seok Ha Hong, Yeon Ju Yu, Seung Beom Han

Introduction

This study investigated the association between medication status and total hip arthroplasty (THA) complications in patients with inflammatory bowel disease (IBD), considering varying illness severities.

Materials and methods

This retrospective analysis of the National Health Insurance Review and Assessment Service database in South Korea, included patients undergoing unilateral THA between 2012 and 2022, specifically those diagnosed with IBD. Propensity score matching was used to adjust for baseline characteristics between IBD and non-IBD cohorts, with a matching ratio of 1:10.

Results

There was a significant difference between the IBD (n = 962) and non-IBD matched groups (n = 9,620) in terms of chronic periprosthetic joint infection (PJI) (2.1 vs. 1.3%, P= 0.03) but not with acute PJI or other surgical complications (periprosthetic fracture, dislocation, and aseptic loosening). While medication use overall was not associated with PJI, only corticosteroid use among IBD medications was significantly associated with PJI among IBD medications (OR: 2.79 [1.03–10.68], P = 0.04). Specifically, multivariable analysis revealed that corticosteroid use within one year before THA was associated with a significant increase in PJI risk (OR: 3.30 [1.21–10.86], P = 0.02). Patients with IBD who were not using steroids did not show an increased risk of PJI.

Conclusions

While IBD increased the risk of chronic PJI, the risk was remarkable in patients using steroids, particularly in the context of poorly controlled IBD and acute flares-up. Preoperative steroid use within one year before THA conferred the greatest risk. Attention should be directed towards recognizing the risk of steroid use before THA.

Level of evidence

Level III, Prognostic.

本研究调查了炎症性肠病(IBD)患者的药物状况与全髋关节置换术(THA)并发症之间的关系,考虑了不同的疾病严重程度。材料和方法:对韩国国民健康保险审查和评估服务数据库进行回顾性分析,包括2012年至2022年间接受单侧THA的患者,特别是诊断为IBD的患者。倾向评分匹配用于调整IBD和非IBD队列之间的基线特征,匹配比例为1:10。结果:IBD组(n = 962)与非IBD匹配组(n = 9620)在慢性假体周围关节感染(PJI)方面有显著差异(2.1 vs. 1.3%, P= 0.03),但在急性PJI或其他手术并发症(假体周围骨折、脱位和无菌性松动)方面无显著差异。虽然总体药物使用与PJI无关,但IBD药物中只有皮质类固醇的使用与IBD药物中的PJI显著相关(OR: 2.79 [1.03-10.68], P = 0.04)。具体而言,多变量分析显示,THA前一年内使用皮质类固醇与PJI风险显著增加相关(OR: 3.30 [1.21-10.86], P = 0.02)。未使用类固醇的IBD患者未显示PJI风险增加。结论:虽然IBD增加了慢性PJI的风险,但使用类固醇的患者风险显著,特别是在IBD控制不良和急性发作的情况下。术前在THA前一年内使用类固醇的风险最大。应注意在全髋关节置换术前使用类固醇的风险。证据等级:III级,预后。
{"title":"Inflammatory bowel disease and its association with increased PJI risk in total hip arthroplasty: the role of steroid use","authors":"Seok Ha Hong,&nbsp;Yeon Ju Yu,&nbsp;Seung Beom Han","doi":"10.1007/s00402-025-06094-2","DOIUrl":"10.1007/s00402-025-06094-2","url":null,"abstract":"<div><h3>Introduction</h3><p>This study investigated the association between medication status and total hip arthroplasty (THA) complications in patients with inflammatory bowel disease (IBD), considering varying illness severities.</p><h3>Materials and methods</h3><p>This retrospective analysis of the National Health Insurance Review and Assessment Service database in South Korea, included patients undergoing unilateral THA between 2012 and 2022, specifically those diagnosed with IBD. Propensity score matching was used to adjust for baseline characteristics between IBD and non-IBD cohorts, with a matching ratio of 1:10.</p><h3>Results</h3><p>There was a significant difference between the IBD (<i>n</i> = 962) and non-IBD matched groups (<i>n</i> = 9,620) in terms of chronic periprosthetic joint infection (PJI) (2.1 vs. 1.3%, <i>P</i>= 0.03) but not with acute PJI or other surgical complications (periprosthetic fracture, dislocation, and aseptic loosening). While medication use overall was not associated with PJI, only corticosteroid use among IBD medications was significantly associated with PJI among IBD medications (OR: 2.79 [1.03–10.68], <i>P</i> = 0.04). Specifically, multivariable analysis revealed that corticosteroid use within one year before THA was associated with a significant increase in PJI risk (OR: 3.30 [1.21–10.86], <i>P</i> = 0.02). Patients with IBD who were not using steroids did not show an increased risk of PJI.</p><h3>Conclusions</h3><p>While IBD increased the risk of chronic PJI, the risk was remarkable in patients using steroids, particularly in the context of poorly controlled IBD and acute flares-up. Preoperative steroid use within one year before THA conferred the greatest risk. Attention should be directed towards recognizing the risk of steroid use before THA.</p><h3>Level of evidence</h3><p>Level III, Prognostic.</p></div>","PeriodicalId":8326,"journal":{"name":"Archives of Orthopaedic and Trauma Surgery","volume":"145 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower incidence of new onset depressive mood disorders associated with early postoperative weight-bearing versus non-weight bearing following fixation of femur and tibia fractures 股骨和胫骨骨折固定术后早期负重与非负重相关的新发抑郁情绪障碍发生率较低。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-14 DOI: 10.1007/s00402-025-06087-1
Nicholas G. Belt, Andrew J. Moyal, Luc M. Fortier, Robert J. Burkhart, Jeremy M. Adelstein, Logan M. Good, Joshua K. Napora

Introduction

Lower extremity fractures are common orthopaedic injuries and often require surgical intervention, which has been shown to significantly impact both the physical recovery and psychological well-being of patients. Given the high prevalence of psychiatric disorders following lower extremity injuries, understanding the relationship between postoperative weight bearing restrictions and psychiatric outcomes is important for improving patient recovery. It was hypothesized that patients with lower extremity fractures who were allowed early weight bearing postoperatively would have lower rates of new-onset psychiatric diagnoses.

Methods

The TriNetX U.S Collaborative Network database was used to identify patients without prior psychiatric diagnoses who underwent either intramedullary nailing (IMN) or open reduction and internal fixation (ORIF) for femur and/or tibial fractures. The IMN and ORIF cohorts were matched based on age, sex, race, diabetes mellitus, and obesity. Psychiatric outcomes included depressive and anxiety disorders, substance use disorders, and psychotropic medication prescriptions. Outcomes were compared at early (1–7 days), intermediate (7 days-2 months), and long term (2 months-2 years) postoperative periods.

Results

After matching, 7410 patients per cohort were included (IMN n = 7410; ORIF n = 7410; total N = 14,820). The rates of developing a new early (1–7 days) postoperative psychiatric diagnosis did not differ significantly between the IMN and ORIF cohorts. However, IMN was associated with a significantly lower rate of depressive mood disorders during the intermediate period (0.65% vs. 1.0%, p = 0.02) and over the two-year follow-up (3.1% vs. 3.7%, p = 0.03). After two years, IMN was associated with lower opioid use disorder compared to ORIF (0.20% vs. 0.50%, p = 0.012). There were no significant differences in the rates of anxiety disorders, substance use disorders, or psychotropic medication prescriptions at any timepoints.

Conclusions

Early weight-bearing facilitated by IMN may be associated with a lower incidence of depressive mood disorders compared to delayed weight-bearing with ORIF. However, overall psychiatric outcomes were similar in this study. This suggests that other factors such as pain management and rehabilitation may play a more important role in postoperative psychiatric health.

下肢骨折是一种常见的骨科损伤,经常需要手术干预,已被证明对患者的身体恢复和心理健康都有显著影响。鉴于下肢损伤后精神疾病的高发率,了解术后负重限制与精神预后之间的关系对于改善患者的康复非常重要。假设下肢骨折患者术后早期负重会有较低的新发精神病诊断率。方法:TriNetX美国协作网络数据库用于识别无精神病学诊断的患者,这些患者接受了髓内钉(IMN)或切开复位内固定(ORIF)治疗股骨和/或胫骨骨折。IMN组和ORIF组根据年龄、性别、种族、糖尿病和肥胖进行匹配。精神病学结果包括抑郁和焦虑障碍、物质使用障碍和精神药物处方。比较术后早期(1-7天)、中期(7天-2个月)和长期(2个月-2年)的结果。结果:匹配后,每个队列纳入7410例患者(IMN n = 7410; ORIF n = 7410;总n = 14820)。术后早期(1-7天)出现新的精神科诊断的比率在IMN组和ORIF组之间没有显著差异。然而,在中期(0.65% vs. 1.0%, p = 0.02)和两年随访期间(3.1% vs. 3.7%, p = 0.03), IMN与抑郁情绪障碍的发生率显著降低相关。两年后,与ORIF相比,IMN与更低的阿片类药物使用障碍相关(0.20%比0.50%,p = 0.012)。在任何时间点上,焦虑症、物质使用障碍或精神药物处方的发生率没有显著差异。结论:与ORIF延迟负重相比,IMN促进的早期负重可能与抑郁情绪障碍的发生率较低有关。然而,在这项研究中,总体的精神病学结果是相似的。这表明,疼痛管理和康复等其他因素可能在术后精神健康中发挥更重要的作用。
{"title":"Lower incidence of new onset depressive mood disorders associated with early postoperative weight-bearing versus non-weight bearing following fixation of femur and tibia fractures","authors":"Nicholas G. Belt,&nbsp;Andrew J. Moyal,&nbsp;Luc M. Fortier,&nbsp;Robert J. Burkhart,&nbsp;Jeremy M. Adelstein,&nbsp;Logan M. Good,&nbsp;Joshua K. Napora","doi":"10.1007/s00402-025-06087-1","DOIUrl":"10.1007/s00402-025-06087-1","url":null,"abstract":"<div><h3>Introduction</h3><p>Lower extremity fractures are common orthopaedic injuries and often require surgical intervention, which has been shown to significantly impact both the physical recovery and psychological well-being of patients. Given the high prevalence of psychiatric disorders following lower extremity injuries, understanding the relationship between postoperative weight bearing restrictions and psychiatric outcomes is important for improving patient recovery. It was hypothesized that patients with lower extremity fractures who were allowed early weight bearing postoperatively would have lower rates of new-onset psychiatric diagnoses.</p><h3>Methods</h3><p>The TriNetX U.S Collaborative Network database was used to identify patients without prior psychiatric diagnoses who underwent either intramedullary nailing (IMN) or open reduction and internal fixation (ORIF) for femur and/or tibial fractures. The IMN and ORIF cohorts were matched based on age, sex, race, diabetes mellitus, and obesity. Psychiatric outcomes included depressive and anxiety disorders, substance use disorders, and psychotropic medication prescriptions. Outcomes were compared at early (1–7 days), intermediate (7 days-2 months), and long term (2 months-2 years) postoperative periods.</p><h3>Results</h3><p>After matching, 7410 patients per cohort were included (IMN <i>n</i> = 7410; ORIF <i>n</i> = 7410; total <i>N</i> = 14,820). The rates of developing a new early (1–7 days) postoperative psychiatric diagnosis did not differ significantly between the IMN and ORIF cohorts. However, IMN was associated with a significantly lower rate of depressive mood disorders during the intermediate period (0.65% vs. 1.0%, <i>p</i> = 0.02) and over the two-year follow-up (3.1% vs. 3.7%, <i>p</i> = 0.03). After two years, IMN was associated with lower opioid use disorder compared to ORIF (0.20% vs. 0.50%, <i>p</i> = 0.012). There were no significant differences in the rates of anxiety disorders, substance use disorders, or psychotropic medication prescriptions at any timepoints.</p><h3>Conclusions</h3><p>Early weight-bearing facilitated by IMN may be associated with a lower incidence of depressive mood disorders compared to delayed weight-bearing with ORIF. However, overall psychiatric outcomes were similar in this study. This suggests that other factors such as pain management and rehabilitation may play a more important role in postoperative psychiatric health.</p></div>","PeriodicalId":8326,"journal":{"name":"Archives of Orthopaedic and Trauma Surgery","volume":"145 1","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145285337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resection arthroplasty for deep shoulder infection in a native shoulder with an intact rotator cuff: a salvage option when reverse shoulder arthroplasty is not feasible 肩关节切除成形术治疗肩袖完好的天然肩关节深部感染:当反向肩关节成形术不可行时的一种挽救选择。
IF 2.1 3区 医学 Q2 ORTHOPEDICS Pub Date : 2025-10-13 DOI: 10.1007/s00402-025-06084-4
Yong Girl Rhee, Seung Ho Jung, Soong Hwan Cho, Tae Hyun Kyeong, Jin Jung, Sung Jun Park, Sung-Min Rhee
AbstractSection Background

Resection arthroplasty is a salvage procedure for uncontrolled deep infection of the shoulder. Previous studies have reported poor functional outcomes, especially in patients with rotator cuff deficiency. We hypothesized that, although overall outcomes might be limited, patients with preserved rotator cuff tendons could still achieve pain relief and functional improvement after resection arthroplasty.

AbstractSection Methods

Between 2001 and 2025, 69 patients underwent surgery for deep shoulder infection. Twenty-seven had resection arthroplasty, of whom 14 were excluded (infection after hemiarthroplasty, chronic infection without bone involvement, full-thickness cuff tear, or follow-up < 2 years). Thirteen patients (mean age, 57 years; range, 39–86) with native shoulders and intact or partial-thickness rotator cuff tears were analyzed. The mean follow-up was 48.8 months (range, 24–180). Pain [visual analogue scale (VAS) at rest and during motion], shoulder motion (active forward flexion, external rotation, internal rotation), and functional scores (University of California Los Angeles [UCLA], Constant) were assessed. Infection control was monitored with white blood cell count, erythrocyte sedimentation rate, and C-reactive protein. Pre- and postoperative values were compared using paired t-tests after normality testing.

AbstractSection Results

VAS during motion improved from 6.5 to 2.3, and VAS at rest improved to 0.4. Forward flexion increased from 32.7° to 97.7°, and external rotation from 9.1° to 27.3° (all p < 0.01). UCLA and Constant scores improved from 9.6 to 29.4 to 25.7 and 60.6, respectively (p < 0.01). Ten of 13 patients reported satisfaction ≥ 6/10. One patient required additional debridement, but no reconstructive conversion was performed.

AbstractSection Conclusion

Resection arthroplasty in native shoulders with preserved rotator cuff tendons provided reliable infection control, substantial pain relief, and functional improvement at mid-term follow-up (24–180 months). These findings support its role as a salvage option when reverse shoulder arthroplasty is not feasible. Limitations include the retrospective design, small sample size, and heterogeneous follow-up period.

AbstractSection Level of evidence

Level IV, retrospective study.

【摘要】章节背景:肩关节置换术是治疗无法控制的肩部深部感染的一种救助性手术。先前的研究报道了较差的功能结果,特别是肩袖缺陷患者。我们假设,尽管总体结果可能有限,但保留肩袖肌腱的患者在关节置换术后仍然可以实现疼痛缓解和功能改善。【摘要】方法2001 ~ 2025年,69例肩部深部感染患者行手术治疗。27例行关节置换术,其中14例排除(半关节置换术后感染、无骨累及的慢性感染、全层袖带撕裂或随访2年)。我们分析了13例肩原发、肩袖完整或部分撕裂的患者(平均年龄57岁,范围39-86岁)。平均随访48.8个月(范围24-180)。评估疼痛[休息和运动时的视觉模拟量表(VAS)]、肩部运动(主动前屈、外旋、内旋)和功能评分(加州大学洛杉矶分校[UCLA], Constant)。用白细胞计数、红细胞沉降率和c反应蛋白监测感染控制。正态性检验后,使用配对t检验比较术前和术后值。【摘要】节结果运动时VAS由6.5提高到2.3,静止时VAS提高到0.4。前屈从32.7°增加到97.7°,外旋从9.1°增加到27.3°(p < 0.01)。UCLA和Constant的得分分别从9.6分提高到29.4分、25.7分和60.6分(p < 0.01)。13例患者中有10例满意度≥6/10。1例患者需要进一步清创,但未进行重建转换。结论在中期随访(24-180个月)中,保留肩袖肌腱的自体肩关节置换术可可靠地控制感染,显著缓解疼痛,改善功能。这些发现支持其作为一种补救性选择,当反向肩关节置换术不可行的作用。局限性包括回顾性设计、小样本量和异质性随访期。【摘要】证据等级四级,回顾性研究。
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引用次数: 0
期刊
Archives of Orthopaedic and Trauma Surgery
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