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A Review: Discussion of Factors Affecting the Efficacy of UV Inactivation 紫外线灭活效果影响因素的探讨
Pub Date : 2022-09-27 DOI: 10.31579/2690-4861/258
Mengmeng Li
UV can achieve the sterilization of clean and nontoxic by-products, and the article makes clear the way in which data such as irradiance and dose are taken. The article data indicates that higher bactericidal efficacy can be achieved for most bacteria at doses of 4 mJ/cm2 for irradiance 1.0 mW/cm2 and 0.06-0.30 mW/cm2 for irradiance 11 mJ/cm2. The value of irradiance ignored the attenuation of LED during long-term use. By comparing the bactericidal effect of single layered and multi-layered bacteria, the degree of cleanliness achievable by UV bactericidal is illustrated, and it is reminded that safety protection should be taken care of during use.
紫外线可以实现对清洁无毒副产品的杀菌,并明确了辐照度和剂量等数据的获取方式。文章数据表明,对于辐照1.0mW/cm2,在4mJ/cm2的剂量和对于辐照11mJ/cm2,在0.06-0.30mW/cm2的剂量下,可以对大多数细菌实现更高的杀菌功效。辐照度值忽略了LED在长期使用过程中的衰减。通过比较单层和多层细菌的杀菌效果,说明了紫外线杀菌可达到的清洁度,并提醒在使用过程中应注意安全保护。
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引用次数: 0
Factors affecting long-term remission in patients with FSGS and NS. 影响FSGS和NS患者长期缓解的因素。
Pub Date : 2022-09-27 DOI: 10.31579/2690-4861/247
NS. Claudio Bazzi
In FSGS with Nephrotic Syndrome (NS) 23 patients (61%) of 38 with functional outcome are in remission with very long follow up (from 60 to 331 months) after treatment with Steroids alone or in combination with Cyclophosphamide. It would be interesting to assess whether in 11 patients with follow up from 5 to 27.6 years some parameters are associated with less severe disease favouring very long term remission. Three parameters were considered [age
在FSGS合并肾病综合征(NS)中,38例具有功能结局的患者中有23例(61%)在单独使用类固醇或联合环磷酰胺治疗后经过很长时间的随访(60至331个月)后缓解。在随访5至27.6年的11例患者中,评估一些参数是否与较轻的疾病相关,有利于长期缓解,这将是一件有趣的事情。考虑三个参数[年龄
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引用次数: 0
COL4A1 with Cerebral Small Vessel Disease and Multiple Anomalous cerebral vascular origins: A case report COL4A1合并脑血管病和多发性脑血管异常起源1例报告
Pub Date : 2022-09-27 DOI: 10.31579/2690-4861/252
Shusheng Zhu
Cerebral small vessel disease (cSVD) is a main cause of stroke, cognitive impairment, and vascular dementia. COL4A1 mutations have been identified as a cause of hereditary cerebral small vessel disease. COL4A1 mutation is associated with nephropathy, aneurysms, and muscle cramps, which we call the HANAC syndrome. Mutations in COL4A1 have recently been identified in both a mouse model and families, characterized by cystic brain cavities and cerebral white-matter lesions. But it has not been reported with vascular malformations. We here first report a case of COL4A1 with cerebral small vessel disease and multiple anomalous cerebral vascular origins.
脑血管病(cSVD)是中风、认知障碍和血管性痴呆的主要原因。COL4A1突变已被确定为遗传性脑血管疾病的一个原因。COL4A1突变与肾病、动脉瘤和肌肉痉挛有关,我们称之为HANAC综合征。最近在小鼠模型和家族中发现了COL4A1突变,其特征是囊性脑腔和脑白质病变。但尚未见血管畸形的报道。我们在此首次报告一例COL4A1合并脑小血管疾病和多发性脑血管异常起源。
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引用次数: 0
A Case of Adrenal Pheochromocytoma Presenting with Anxiety 肾上腺嗜铬细胞瘤伴焦虑1例
Pub Date : 2022-07-21 DOI: 10.31579/2690-4861/225
D. Karakaya
Pheochromocytoma is a rare, neuroendocrine tumor secreting catecholamine, arising from chromaffin cells of the adrenal medulla. Also, very rare cause of secondary hypertension in pediatric age, and however, it is important to suspect. Presentation of this tumor is highly variable but the most common pediatric cases being persistent hypertension, tachycardia, sweating, and headache. In addition, anxiety, weight loss and recurrent hypertension may also appear among the clinical manifestations of the disease. The diagnosis requires measurement of plasma metanephrines, with imaging studies performed for localization and identification of metastatic lesions. The definitive management of hypertension is surgical. We present a case with pheochromocytoma that was previously diagnosed as anxiety due to tachycardia associated with hypertension.
嗜铬细胞瘤是一种罕见的分泌儿茶酚胺的神经内分泌肿瘤,起源于肾上腺髓质的嗜铬细胞。此外,儿童年龄段继发性高血压的病因非常罕见,但值得怀疑。这种肿瘤的表现变化很大,但最常见的儿科病例是持续性高血压、心动过速、出汗和头痛。此外,焦虑、体重减轻和复发性高血压也可能出现在该疾病的临床表现中。诊断需要测量血浆后肾,并进行影像学研究以定位和识别转移性病变。高血压的最终治疗方法是外科手术。我们报告了一例嗜铬细胞瘤,先前诊断为与高血压相关的心动过速引起的焦虑。
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引用次数: 0
A Rare Anatomic Variant of the Superficial Palmar Branch of the Radial Artery Used for Arteriovenous Fistula Creation 一种罕见的桡动脉掌浅支用于动静脉瘘形成的解剖学变体
Pub Date : 2022-07-21 DOI: 10.31579/2690-4861/235
Tauhidul Alam Choudhury
Anatomical knowledge regarding the variant branching patterns of the radial artery is considerably crucial for interventionalists, vascular, and plastic surgeons. We report a case of a rare variant branching pattern where the superficial palmar branch of the radial artery originated from the radial artery in the forearm instead of the wrist with a subcutaneous course in a 52-year-old patient with diabetic end-stage kidney disease who required haemodialysis initiation. This variant branch was used as inflow for the creation of the arteriovenous fistula for haemodialysis access.
对于介入医师、血管外科医生和整形外科医生来说,关于桡动脉分支形态的解剖学知识是相当重要的。我们报告一例罕见的变异分支模式,桡动脉的掌浅分支起源于前臂的桡动脉,而不是手腕,并有皮下病程,这是一例52岁的糖尿病终末期肾病患者,需要血液透析。该变异分支被用作血液透析通道的动静脉瘘形成的流入。
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引用次数: 0
Prevalence and Clinico-Biological Characteristics of Viral Hepatitis B and C in Chronic Hemodialysis Patients at the National Hospital Center of Nouakchott-Mauritania 努瓦克肖特-毛里塔尼亚国家医院中心慢性血液透析患者中病毒性乙型和丙型肝炎的患病率和临床生物学特征
Pub Date : 2022-07-21 DOI: 10.31579/2690-4861/228
M. O. Ould Salem
Introduction: Chronic renal insufficiency is a common pathology both nationally and worldwide, infections with hepatitis B and C viruses are the most common infectious complication in chronic hemodialysis patients. Objective: The objective of this study was to determine the prevalence of hepatitis B and C in chronic hemodialysis patients at the National Hospital Center of Nouakchott and to identify the risk factors for these infections as well as their clinical and biological complications in this population Material and Methods: This is a prospective study carried out at the nephrology-hemodialysis department of the National Hospital of Nouakchott over a period of one year from 1st, 2016 to December 31st, 2016 Demographic, clinical, epidemiological, and biological data were collected using a pre-established survey form The search for HBsAg was done by the ELISA technique and the detection of anti-HCV antibodies was done by the CMIA technique (Abbott®), the HCV RNA was searched for by real-time PCR (Abbott) Results The average age of our patients was 52 years old with a female predominance The prevalence of hepatitis B was 24.27% and that of hepatitis C was 5.82%, 1.92% of patients were coinfected with HBV and HCV The duration of dialysis and the number of transfusions were the main risk factors for catching these infections. Conclusion the risk factors found in our study were comparable to the literature; the high prevalence of hepatitis B in our series could be linked to its high prevalence in the general population but also to a nosocomial infection.
引言:慢性肾功能不全是国内外常见的病理,乙型肝炎和丙型肝炎病毒感染是慢性血液透析患者最常见的感染并发症。目的:本研究的目的是确定努瓦克肖特国立医院中心慢性血液透析患者中乙型和丙型肝炎的患病率,并确定这些感染的危险因素及其临床和生物学并发症。材料和方法:这是一项在肾病血液透析中进行的前瞻性研究2016年1月1日至2016年12月31日,在一年的时间里,使用预先建立的调查表收集了人口统计学、临床、流行病学和生物学数据。通过ELISA技术搜索HBsAg,通过CMIA技术(Abbott®)检测抗-HCV抗体,结果本组患者平均年龄52岁,以女性为主。乙型肝炎和丙型肝炎的患病率分别为24.27%和5.82%,1.92%的患者同时感染了HBV和HCV。透析时间和输血次数是感染这些病毒的主要危险因素。结论本研究发现的危险因素与文献具有可比性;在我们的系列中,乙型肝炎的高患病率可能与它在普通人群中的高发病率有关,也可能与医院感染有关。
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引用次数: 1
Evans Syndrome in pregnancy – Case report of two successful pregnancies in a woman ; Review of Literature. 妊娠期埃文斯综合征——一名妇女两次成功妊娠的病例报告;文献综述。
Pub Date : 2022-07-21 DOI: 10.31579/2690-4861/229
N. Navakumar
Evans syndrome is a rare autoimmune disease in which an individual's antibodies attacks the body's own red Autoimmune blood cells and platelets. There is a coexistence of Immune thrombocytopenia (ITP) with haemolytic anaemia (AIHA) with immune neutropenia sometimes in the absence of known underlying etiology.1Association of Evans syndrome with pregnancy is very rare, and only a few cases have been published in medical literature. No definite treatment protocols are defined. Treatment options during pregnancy are further limited due to concerns of teratogenic effect of pharmacological agents. Evans syndrome can be diagnosed with a full blood count film and a direct Coombs test. We describe here a rare case that was diagnosed as secondary Evans syndrome with SLE complicating pregnancy that resulted in two live births in a woman. We have also briefly discussed the pathophysiology, clinical features, diagnosis and the possible treatment options and outcome of Evans syndrome in pregnancy
埃文斯综合征是一种罕见的自身免疫性疾病,个体的抗体攻击身体自身的红色自身免疫血细胞和血小板。免疫性血小板减少症(ITP)、溶血性贫血(AIHA)和免疫性中性粒细胞减少症共存,有时在缺乏已知潜在病因的情况下。1埃文斯综合征与妊娠的关联非常罕见,医学文献中只发表了少数病例。没有明确的治疗方案。由于担心药物的致畸作用,妊娠期间的治疗选择进一步受到限制。埃文斯综合征可以通过全血细胞计数片和直接库姆斯试验来诊断。我们在这里描述了一个罕见的病例,被诊断为继发性埃文斯综合征合并SLE合并妊娠,导致一名妇女两次活产。我们还简要讨论了妊娠期Evans综合征的病理生理学、临床特征、诊断以及可能的治疗方案和结果
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引用次数: 0
Disseminated Mycobacterium Bovis 弥散性牛分枝杆菌
Pub Date : 2022-07-21 DOI: 10.31579/2690-4861/232
A. Ekladious
Intravesical BacillusChalmette- Guerin (BCG) still a popular medication for non-invasive bladdercancer in the low-income country, one of the uncommon side effects is disseminated Mycobacterium Bovis. We present a patient who presented with haematuria, diagnosed as urothelial superficial bladder cancer, treated with incomplete resectionand intravesical BCG, 6 months after treatment, he presented with increasing shortness of breath, headache and abdominal pain, diagnosed as tuberculous, meningitis, massive pleural effusion, granulomatous hepatitis he responded very well to anti tuberculous treatment.
膀胱内注射卡介苗(BCG)在低收入国家仍然是治疗非侵入性膀胱癌的常用药物,其中一种不常见的副作用是传播性牛分枝杆菌。我们报告了一名患者,他出现血尿,诊断为尿路上皮浅表膀胱癌症,接受了不完全切除和膀胱内BCG治疗,治疗6个月后,他出现呼吸急促、头痛和腹痛加重,诊断为结核、脑膜炎、大量胸腔积液,肉芽肿性肝炎他对抗结核治疗反应良好。
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引用次数: 0
A Case Report: Gangrenous Sub-hepatic Appendicitis in Pregnancy 妊娠期坏疽性肝下阑尾炎1例报告
Pub Date : 2022-06-28 DOI: 10.46527/2582-5038.220
Saeed Abedelkarim, V. Nguyen, Enas Abdelraheem, Fatima Elnadi, A. Gaboura
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引用次数: 0
Hemoperitoneum Following Liver Rupture in a Post ERCP Patient: A Case Report ERCP术后肝破裂后腹膜出血1例报告
Pub Date : 2022-06-22 DOI: 10.46527/2582-5038.219
R. Jhaveri, Vishakha Kalikar, R. Sheth, R. Patankar
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引用次数: 0
期刊
International journal of clinical case reports and reviews : open access
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