Pub Date : 2018-06-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.03.008
L. Suyun, He Yuan, Liu Xiaoqian, Ji Linlin, Chunxia Chen, Li Qianyu
Objective To evaluate the effectiveness of nutritional support in the treatment of primary chylous reflux obstacle caused by primary lymphatic dysplasia among infants and investigate the effects of the essential components of therapeutic formula milk in treating this disease. Methods Seven infants, who were diagnosed at Beijing Shijitan Hospital between 2012 and 2014 with primary chylous reflux obstacle and aged (8.9±4.6) months at the onset, were retrospectively analyzed to evaluate effectiveness of the nutrition support and prognosis of the disease. Results After personalized enteral nutrition support(using proteins, short peptides and medium-chain triglyceride) of (8.3±2.8) months, heights and weights of all the seven infants were kept between the 3rd and 97th percentile lines, and the growth curve showed onward and upward trend. Their plasma albumin levels reached (43.7±4.4)g/L. The infants defecated 1-2 times a day and the texture of feces was formed and soft with yellow color. Conclusion Clinical symptoms and physical signs of the seven infants were improved after nutrition support, which contributed to the recovery. Key words: Primary lymphatic dysplasia; Disorders of the circulation of chyle; Chylothorax; Chylous ascitis; Nutritional support
{"title":"Role of nutritional support in the treatment of infants with primary chylous reflux obstacle","authors":"L. Suyun, He Yuan, Liu Xiaoqian, Ji Linlin, Chunxia Chen, Li Qianyu","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.03.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.03.008","url":null,"abstract":"Objective \u0000To evaluate the effectiveness of nutritional support in the treatment of primary chylous reflux obstacle caused by primary lymphatic dysplasia among infants and investigate the effects of the essential components of therapeutic formula milk in treating this disease. \u0000 \u0000 \u0000Methods \u0000Seven infants, who were diagnosed at Beijing Shijitan Hospital between 2012 and 2014 with primary chylous reflux obstacle and aged (8.9±4.6) months at the onset, were retrospectively analyzed to evaluate effectiveness of the nutrition support and prognosis of the disease. \u0000 \u0000 \u0000Results \u0000After personalized enteral nutrition support(using proteins, short peptides and medium-chain triglyceride) of (8.3±2.8) months, heights and weights of all the seven infants were kept between the 3rd and 97th percentile lines, and the growth curve showed onward and upward trend. Their plasma albumin levels reached (43.7±4.4)g/L. The infants defecated 1-2 times a day and the texture of feces was formed and soft with yellow color. \u0000 \u0000 \u0000Conclusion \u0000Clinical symptoms and physical signs of the seven infants were improved after nutrition support, which contributed to the recovery. \u0000 \u0000 \u0000Key words: \u0000Primary lymphatic dysplasia; Disorders of the circulation of chyle; Chylothorax; Chylous ascitis; Nutritional support","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"181-185"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43030350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.03.007
Xuefeng Ni, Wenbing Mou, L. Jiao, K. Yu
Objective A analyze the relation between abdominal fat and diabetes mellitus in elderly person aged 51-100. Methods According to the abdominal CT scan in 2015 to 2016 of 162 patients in Peking Union Medical College Hospital, the volume and distribution of their abdominal fat were measured to analyze the relationship between abdominal fat and diabetes mellitus. Results People aged 51-75, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have less abdominal visceral fat[(63.61±24.95)mm3vs.( 70.39±31.33)mm3t=-1.229, P=0.22], tend to have more abdominal subcutaneous fat[(89.03±32.94)mm3vs. (83.18±43.25)mm3, t=1.070, P=0.43), but both are not significant difference, total abdominal fat is similar between the two group[(152.64±46.84)mm3vs. (151.84±61.32)mm3 , t=0.076, P=0.94], abdominal visceral fat percentage is significantly lower[(41.8±10.9)% vs. (46.9±10.9)%, t=-2.346, P=0.02]. People aged 76-100, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have more abdominal visceral fat[(68.29±39.58)mm3vs. (51.56±25.89)mm3), abdominal subcutaneous fat[(84.65±41.30)mm3vs. (75.29±42.04)mm3], total abdominal fat[(152.96±69.92)mm3vs. (126.86±62.13)mm3], abdominal visceral fat percentage[(43.7±12)% vs. (41.1±11.8)%], all of them are not significant (t=1.885, 0.839, 1.479, 0.810, respectively; P=0.07, 0.40, 0.15, 0.42, respectively). Conclusions In people aged 51-75, those who had increased ratio of abdominal visceral fat to total abdominal fat were more prone to diabetes or fasting hyperglycemia. In people aged 76-100, no significant correlation was detected between abdominal fat and disorder of glucose metabolism. Key words: Diabetes mellitus, type 2; Obesity; Subcutaneous fat; Viscecal fat
{"title":"Relationship between abdominal fat distribution and diabetes in middle-aged and old people","authors":"Xuefeng Ni, Wenbing Mou, L. Jiao, K. Yu","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.03.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.03.007","url":null,"abstract":"Objective \u0000A analyze the relation between abdominal fat and diabetes mellitus in elderly person aged 51-100. \u0000 \u0000 \u0000Methods \u0000According to the abdominal CT scan in 2015 to 2016 of 162 patients in Peking Union Medical College Hospital, the volume and distribution of their abdominal fat were measured to analyze the relationship between abdominal fat and diabetes mellitus. \u0000 \u0000 \u0000Results \u0000People aged 51-75, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have less abdominal visceral fat[(63.61±24.95)mm3vs.( 70.39±31.33)mm3t=-1.229, P=0.22], tend to have more abdominal subcutaneous fat[(89.03±32.94)mm3vs. (83.18±43.25)mm3, t=1.070, P=0.43), but both are not significant difference, total abdominal fat is similar between the two group[(152.64±46.84)mm3vs. (151.84±61.32)mm3 , t=0.076, P=0.94], abdominal visceral fat percentage is significantly lower[(41.8±10.9)% vs. (46.9±10.9)%, t=-2.346, P=0.02]. People aged 76-100, no abnormal glucose metabolism group compare with diabetes or fast hyperglycemia group, tend to have more abdominal visceral fat[(68.29±39.58)mm3vs. (51.56±25.89)mm3), abdominal subcutaneous fat[(84.65±41.30)mm3vs. (75.29±42.04)mm3], total abdominal fat[(152.96±69.92)mm3vs. (126.86±62.13)mm3], abdominal visceral fat percentage[(43.7±12)% vs. (41.1±11.8)%], all of them are not significant (t=1.885, 0.839, 1.479, 0.810, respectively; P=0.07, 0.40, 0.15, 0.42, respectively). \u0000 \u0000 \u0000Conclusions \u0000In people aged 51-75, those who had increased ratio of abdominal visceral fat to total abdominal fat were more prone to diabetes or fasting hyperglycemia. In people aged 76-100, no significant correlation was detected between abdominal fat and disorder of glucose metabolism. \u0000 \u0000 \u0000Key words: \u0000Diabetes mellitus, type 2; Obesity; Subcutaneous fat; Viscecal fat","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"176-180"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48535199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.03.006
Qizhi An, Xin Tao, Lirui Wang, Chun-wei Li
Objective To investigate the status of body weight, total body fat and skeletal muscle in elderly patients with diabetes. Methods A total of 71 elderly diabetic patients (study group) who met entry criteria and signed informed consent were consecutively enrolled, and 70 healthy subjects (control group) matched for age and gender were selected into the study. Body weight, body mass index (BMI), waist-to-hip ratio (WHR), total body fat (TBF), abdominal fat (AF), visceral fat (VF), visceral fat area (VFA), fat-free mass (FFM), total body muscle (TBM), skeletal muscle (SM), skeletal muscle height index (SMHI) and grip strength (GS) were measured by anthropometry and multi-frequency bioelectric impedance analysis. The rate of low weight, overweight and obesity was judged by BMI; the rate of abdominal obesity by WHR; and the status of muscle by TBM, SM, MHI and GS. Results The two groups were comparable at baseline. Compared to the control group, the rate of low weight [36.6% (26/71) vs. 20.0% (14/70), χ2=4.791, P=0.039], weight loss [(1.37±1.57)kg vs. (0.82±1.12)kg, t=2.402, P=0.018], ratio of people who experienced weight loss>5% in 3 months [22.5% (16/71) vs. 8.6% (6/70), χ2=5.219, P=0.035], TBF%[(32.3±5.0)% vs. (30.3±5.2)%, t=2.294, P=0.023], WHR(0.91±0.55 vs. 0.87±0.51, t=2.661, P=0.009), the rate of abdominal obesity[49.3% (35/71) vs. 25.7%(18/70), χ2=8.355, P=0.005], AF[(12.1±3.4)kg vs. (10.3±3.6)kg, t=2.981, P=0.003], VF[(2.9±0.8)kg vs.(2.5±0.9)kg, t=2.853, P=0.005] and VFA[(99.8±26.3)cm2vs. (84.9±31.1)cm2,t=3.045, P=0.003] were increased significantly in study group, while the FFM[(34.9±7.5)kg vs. (37.9±5.6)kg, t=-2.691, P=0.008], SM[(25.8±4.5)kg vs.(27.3±3.5)kg, t=-2.140, P=0.034], SMHI[(9.4±1.8)kg/m2vs. (10.2±1.5)kg/m2,t=-3.081, P=0.002] and GS[(29.3±6.6)kg vs. (31.8±5.7)kg, t=-2.406, P=0.017] were decreased significantly in study group. Conclusion Abnormal weight, abdominal obesity and loss of skeletal muscle were more likely to be observed in elderly patients with diabetes. Key words: Diabetes mellitus; Aged; Body fat; Obesity, abdominal; Skeletal muscle; Grip strength
{"title":"Body weight, body fat and skeletal muscle status in elderly patients with diabetes","authors":"Qizhi An, Xin Tao, Lirui Wang, Chun-wei Li","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.03.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.03.006","url":null,"abstract":"Objective \u0000To investigate the status of body weight, total body fat and skeletal muscle in elderly patients with diabetes. \u0000 \u0000 \u0000Methods \u0000A total of 71 elderly diabetic patients (study group) who met entry criteria and signed informed consent were consecutively enrolled, and 70 healthy subjects (control group) matched for age and gender were selected into the study. Body weight, body mass index (BMI), waist-to-hip ratio (WHR), total body fat (TBF), abdominal fat (AF), visceral fat (VF), visceral fat area (VFA), fat-free mass (FFM), total body muscle (TBM), skeletal muscle (SM), skeletal muscle height index (SMHI) and grip strength (GS) were measured by anthropometry and multi-frequency bioelectric impedance analysis. The rate of low weight, overweight and obesity was judged by BMI; the rate of abdominal obesity by WHR; and the status of muscle by TBM, SM, MHI and GS. \u0000 \u0000 \u0000Results \u0000The two groups were comparable at baseline. Compared to the control group, the rate of low weight [36.6% (26/71) vs. 20.0% (14/70), χ2=4.791, P=0.039], weight loss [(1.37±1.57)kg vs. (0.82±1.12)kg, t=2.402, P=0.018], ratio of people who experienced weight loss>5% in 3 months [22.5% (16/71) vs. 8.6% (6/70), χ2=5.219, P=0.035], TBF%[(32.3±5.0)% vs. (30.3±5.2)%, t=2.294, P=0.023], WHR(0.91±0.55 vs. 0.87±0.51, t=2.661, P=0.009), the rate of abdominal obesity[49.3% (35/71) vs. 25.7%(18/70), χ2=8.355, P=0.005], AF[(12.1±3.4)kg vs. (10.3±3.6)kg, t=2.981, P=0.003], VF[(2.9±0.8)kg vs.(2.5±0.9)kg, t=2.853, P=0.005] and VFA[(99.8±26.3)cm2vs. (84.9±31.1)cm2,t=3.045, P=0.003] were increased significantly in study group, while the FFM[(34.9±7.5)kg vs. (37.9±5.6)kg, t=-2.691, P=0.008], SM[(25.8±4.5)kg vs.(27.3±3.5)kg, t=-2.140, P=0.034], SMHI[(9.4±1.8)kg/m2vs. (10.2±1.5)kg/m2,t=-3.081, P=0.002] and GS[(29.3±6.6)kg vs. (31.8±5.7)kg, t=-2.406, P=0.017] were decreased significantly in study group. \u0000 \u0000 \u0000Conclusion \u0000Abnormal weight, abdominal obesity and loss of skeletal muscle were more likely to be observed in elderly patients with diabetes. \u0000 \u0000 \u0000Key words: \u0000Diabetes mellitus; Aged; Body fat; Obesity, abdominal; Skeletal muscle; Grip strength","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"170-175"},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44678777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.005
Haiyan Xie, K. Yu, Qizhi An, Hong Jiang
Objective To compare differences among measured rest energy expenditure (REE) by using indirect calorimetry (IC) and predictive REE from predictive equations (PE) and human body component analyzer (HBCA). Methods Young and middle-aged healthy volunteers of light manual labor were recruited in this study. REEs were obtained from IC, PE (WHO-Schofield and Harris-Benedict equations) and HBCA. Results A total of 30 healthy participants were included, of whom 12 were males (25-46 years old) with an average age of (37.8±7.4) and 18 were females (26-52 years old) with an average age of (40.4±7.8). Measured REE of the males was (1 848.33±155.01)kcal/d, which was significantly different from the predictive REE result of H-B equation (P=0.003) but not from results of WHO-Schofield equation and HBCA. In females, however, measured REE was (1 294.44±134.23)kcal /d, which was significantly different from predictive REE results of both equations and HBCA, P=0.002(WHO-Schofield), P=0.031(H-B) and P=0.002(HBCA). Results of measured REE were related to weight (P=0.033) and percentage of body fat (P=0.036) in males, and to height and muscle mass (P=0.003) in females. Conclusion In young and middle-aged healthy females of light manual labor, IC represented a more accurate way to measure REE, while in males WHO-Schofield equation and HBCA could be considered as alternative choices to predict REE. Key words: Rest energy expenditure; Indirect calorimetry; Energy predictive equations; Body composition
{"title":"Comparation in calculating rest energy expenditure with indirect calorimetry, predictive equations and human body component analyzer","authors":"Haiyan Xie, K. Yu, Qizhi An, Hong Jiang","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.005","url":null,"abstract":"Objective \u0000To compare differences among measured rest energy expenditure (REE) by using indirect calorimetry (IC) and predictive REE from predictive equations (PE) and human body component analyzer (HBCA). \u0000 \u0000 \u0000Methods \u0000Young and middle-aged healthy volunteers of light manual labor were recruited in this study. REEs were obtained from IC, PE (WHO-Schofield and Harris-Benedict equations) and HBCA. \u0000 \u0000 \u0000Results \u0000A total of 30 healthy participants were included, of whom 12 were males (25-46 years old) with an average age of (37.8±7.4) and 18 were females (26-52 years old) with an average age of (40.4±7.8). Measured REE of the males was (1 848.33±155.01)kcal/d, which was significantly different from the predictive REE result of H-B equation (P=0.003) but not from results of WHO-Schofield equation and HBCA. In females, however, measured REE was (1 294.44±134.23)kcal /d, which was significantly different from predictive REE results of both equations and HBCA, P=0.002(WHO-Schofield), P=0.031(H-B) and P=0.002(HBCA). Results of measured REE were related to weight (P=0.033) and percentage of body fat (P=0.036) in males, and to height and muscle mass (P=0.003) in females. \u0000 \u0000 \u0000Conclusion \u0000In young and middle-aged healthy females of light manual labor, IC represented a more accurate way to measure REE, while in males WHO-Schofield equation and HBCA could be considered as alternative choices to predict REE. \u0000 \u0000 \u0000Key words: \u0000Rest energy expenditure; Indirect calorimetry; Energy predictive equations; Body composition","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"90-93"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49532321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.006
Hui-jia Lin
Objective To investigate, through a survey on hospitals, the disciplinary development of pediatric nutrition and the present situation of clinical nutritional support in China, in an effort to inform and promote development of pediatric clinical nutrition. Methods A questionnaire was designed by the group of clinical nutrition, Chinese Pediatric Society, Chinese Medical Association. Respondents were 45 hospitals where members of the group work. The survey included 8 aspects in clinical work. Results Of all the 45 hospitals, 40 were grade-A tertiary hospitals; 4 were grade-B tertiary hospitals; and one was a secondary hospital. 25 (55.6%) of the surveyed hospitals were children's hospitals, and 20 (44.4%) were general hospitals. All the hospitals were divided into 8 groups according to their geographical distribution in China, and East China hosted the most while Northeast China had the least. Nutritional support team (NST) was set up in 32 (71.1%) hospitals, with head of the team majoring in the specialty/subspecialty of pediatric gastroenterology or clinical nutrition. In 39 (86.7%) hospitals, physicians working in the nutrition department were attending or above, and in 38 (84.4%) tertiary hospitals, chief of the nutrition department held an academic title of associate chief or above. 39 (86.7%) hospitals had nutrition clinics, 42 (93.3%) provided nutritional counseling, 40 (88.9%) involved nutritionists in consultations, 25 (55.6%) had independent nutritional rounds. Screening tools for nutritional risk and dysplasia in children(STRONGkids) and screening tool for the assessment of malnutrition in pediatrics (STAMP) were the most widely used tools for malnutrition screening, and the same with self-rating depression scale(SDS) and percentile for nutritional status evaluation. In the most surveyed hospitals, key institutional requirement and procedural protocol were put in place for the nutritional department. Conclusions Pediatric clinical nutrition was developing well in tertiary hospitals in China. NST was established in most institutions. There was strong toolkit for clinical nutritional support and sound administrative institutions. There is room, though, for further improvement. Key words: Pediatrics; Nutritional support; Survey
{"title":"A survey on pediatric nutrition and nutritional support in 45 hospitals","authors":"Hui-jia Lin","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.006","url":null,"abstract":"Objective \u0000To investigate, through a survey on hospitals, the disciplinary development of pediatric nutrition and the present situation of clinical nutritional support in China, in an effort to inform and promote development of pediatric clinical nutrition. \u0000 \u0000 \u0000Methods \u0000A questionnaire was designed by the group of clinical nutrition, Chinese Pediatric Society, Chinese Medical Association. Respondents were 45 hospitals where members of the group work. The survey included 8 aspects in clinical work. \u0000 \u0000 \u0000Results \u0000Of all the 45 hospitals, 40 were grade-A tertiary hospitals; 4 were grade-B tertiary hospitals; and one was a secondary hospital. 25 (55.6%) of the surveyed hospitals were children's hospitals, and 20 (44.4%) were general hospitals. All the hospitals were divided into 8 groups according to their geographical distribution in China, and East China hosted the most while Northeast China had the least. Nutritional support team (NST) was set up in 32 (71.1%) hospitals, with head of the team majoring in the specialty/subspecialty of pediatric gastroenterology or clinical nutrition. In 39 (86.7%) hospitals, physicians working in the nutrition department were attending or above, and in 38 (84.4%) tertiary hospitals, chief of the nutrition department held an academic title of associate chief or above. 39 (86.7%) hospitals had nutrition clinics, 42 (93.3%) provided nutritional counseling, 40 (88.9%) involved nutritionists in consultations, 25 (55.6%) had independent nutritional rounds. Screening tools for nutritional risk and dysplasia in children(STRONGkids) and screening tool for the assessment of malnutrition in pediatrics (STAMP) were the most widely used tools for malnutrition screening, and the same with self-rating depression scale(SDS) and percentile for nutritional status evaluation. In the most surveyed hospitals, key institutional requirement and procedural protocol were put in place for the nutritional department. \u0000 \u0000 \u0000Conclusions \u0000Pediatric clinical nutrition was developing well in tertiary hospitals in China. NST was established in most institutions. There was strong toolkit for clinical nutritional support and sound administrative institutions. There is room, though, for further improvement. \u0000 \u0000 \u0000Key words: \u0000Pediatrics; Nutritional support; Survey","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"94-99"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45668611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.004
Xue-mian Lu, A. LiyaJilili
Objective To establish reference interval of thyroid hormones in pregnant women in Urumqi, standardize the diagnostic criteria of thyroid diseases in pregnancy, assess the iodine nutrition and thyroid function at different stages of pregnancy, and provide evidence to guide iodine supplementation. Methods A cross-sectional survey was performed in 3 731 pregnant women in Urumqi from May 2015 to June 2016. 1 206 of them were in the first trimester, 1 125 in the second and 1 400 in the third. 500 non-pregnant women were recruited as controls. Levels of serum thyrotrophin (TSH), free triiodothyronine (FT3), free thyroxine (FT4), anti-thyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TG) were measured, and urinary iodine levels were detected by arsenic-cerium catalytic spectrophotometry. Results There were statistically significant differences between the pregnant groups and the control group in FT3, FT4, and TSH levels (P 0.05). Conclusions Iodine nutritional status was closely related to gestational age. Abnormal TSH levels were mainly observed in the second and third trimesters, abnormal serum levels of FT3, FT4, anti-TG and anti-TPO in the first trimester, and iodine deficiency in the third trimester. Thyroid function and urinary iodine should be monitored at each trimester during pregnancy. Key words: Pregnant women; Thyroid function tests; Reference interval; Urinary iodine
{"title":"Correlation of thyroid function and iodine nutritional status among pregnant women of Han nationality in Urumqi","authors":"Xue-mian Lu, A. LiyaJilili","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.004","url":null,"abstract":"Objective \u0000To establish reference interval of thyroid hormones in pregnant women in Urumqi, standardize the diagnostic criteria of thyroid diseases in pregnancy, assess the iodine nutrition and thyroid function at different stages of pregnancy, and provide evidence to guide iodine supplementation. \u0000 \u0000 \u0000Methods \u0000A cross-sectional survey was performed in 3 731 pregnant women in Urumqi from May 2015 to June 2016. 1 206 of them were in the first trimester, 1 125 in the second and 1 400 in the third. 500 non-pregnant women were recruited as controls. Levels of serum thyrotrophin (TSH), free triiodothyronine (FT3), free thyroxine (FT4), anti-thyroid peroxidase (anti-TPO) and antithyroglobulin (anti-TG) were measured, and urinary iodine levels were detected by arsenic-cerium catalytic spectrophotometry. \u0000 \u0000 \u0000Results \u0000There were statistically significant differences between the pregnant groups and the control group in FT3, FT4, and TSH levels (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Iodine nutritional status was closely related to gestational age. Abnormal TSH levels were mainly observed in the second and third trimesters, abnormal serum levels of FT3, FT4, anti-TG and anti-TPO in the first trimester, and iodine deficiency in the third trimester. Thyroid function and urinary iodine should be monitored at each trimester during pregnancy. \u0000 \u0000 \u0000Key words: \u0000Pregnant women; Thyroid function tests; Reference interval; Urinary iodine","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"83-89"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45967240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.009
Jing Wang, Ying Zhang, Lili Jiang, Q. Fu, Yanjie Bi, Ru-qian Zhao, H. Bai
Objective To observed the clinical efficacy and safety of high pressure-resistant double-lumen peripherally inserted central catheter (Power PICC) and central venous catheter (CVC) in patients with stem cell transplantation. Methods This was a matched cross-sectional study with 60 patients with leukemia who were treated with catheterization of central venous (30 cases receiving Power PICC vs. 30 cases receiving CVC) during stem cell transplantation in the First Affiliated Hospital of Chinese PLA General Hospital. Indwelling time, success rate of catheterization, complications, velocity and stem cell engraftment time were recorded and compared between the Power PICC group and CVC group. Results There were significant differences between the two groups on indwelling time [(18.47±4.44)min vs. (14.43±1.72)min, t=3.719, P 0.05). Conclusion Power PICC performed better than CVC with well tolerability and satisfactory efficacy, which is worthy of promotion and application in the future. Key words: Peripherally inserted central catheter; Central venous catheter; Hematopoietic stem cell transplantation
{"title":"Clinical effect of power peripherally inserted central catheter and central venous catheter in hematopoietic stem cell transplantation","authors":"Jing Wang, Ying Zhang, Lili Jiang, Q. Fu, Yanjie Bi, Ru-qian Zhao, H. Bai","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.009","url":null,"abstract":"Objective \u0000To observed the clinical efficacy and safety of high pressure-resistant double-lumen peripherally inserted central catheter (Power PICC) and central venous catheter (CVC) in patients with stem cell transplantation. \u0000 \u0000 \u0000Methods \u0000This was a matched cross-sectional study with 60 patients with leukemia who were treated with catheterization of central venous (30 cases receiving Power PICC vs. 30 cases receiving CVC) during stem cell transplantation in the First Affiliated Hospital of Chinese PLA General Hospital. Indwelling time, success rate of catheterization, complications, velocity and stem cell engraftment time were recorded and compared between the Power PICC group and CVC group. \u0000 \u0000 \u0000Results \u0000There were significant differences between the two groups on indwelling time [(18.47±4.44)min vs. (14.43±1.72)min, t=3.719, P 0.05). \u0000 \u0000 \u0000Conclusion \u0000Power PICC performed better than CVC with well tolerability and satisfactory efficacy, which is worthy of promotion and application in the future. \u0000 \u0000 \u0000Key words: \u0000Peripherally inserted central catheter; Central venous catheter; Hematopoietic stem cell transplantation","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"110-114"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44787314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.013
Rui Wang, Yanqing Song, J. Zhao
Objective A discussion of practical models for auditing the prescription of parenteral nutrition by clinical pharmacists of nutrition. Methods A three-dimensional approach to prescription audit of parenteral nutrition by clinical pharmacists, focusing on the stability of the nutritional solution, its pharmacological rationality and the patient’s individual need. Results Establishment of this three-dimensional approach. Conclusion This three-dimensional approach ensures the safety and rationality of parenteral nutrition and gives play to clinical pharmacists. Key words: Total parenteral nutrition; Clinical pharmacist of nutrition; Prescription audit
{"title":"Three dimensions in auditing the prescription of parenteral nutrition: from the perspective of clinical pharmacists of nutrition","authors":"Rui Wang, Yanqing Song, J. Zhao","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.013","url":null,"abstract":"Objective \u0000A discussion of practical models for auditing the prescription of parenteral nutrition by clinical pharmacists of nutrition. \u0000 \u0000 \u0000Methods \u0000A three-dimensional approach to prescription audit of parenteral nutrition by clinical pharmacists, focusing on the stability of the nutritional solution, its pharmacological rationality and the patient’s individual need. \u0000 \u0000 \u0000Results \u0000Establishment of this three-dimensional approach. \u0000 \u0000 \u0000Conclusion \u0000This three-dimensional approach ensures the safety and rationality of parenteral nutrition and gives play to clinical pharmacists. \u0000 \u0000 \u0000Key words: \u0000Total parenteral nutrition; Clinical pharmacist of nutrition; Prescription audit","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"54 1","pages":"125-128"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41281965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.002
Ya Li, Lingling Jiao, Naishi Li, Zhenjie Wang, Hong Jiang, K. Yu
Objective To analyze the effect of health check-up feedback style (HCFS) on the blood glucose level and weight of type 2 diabetes patients aged 75 years and older. Methods 120 consecutive patients with type 2 diabetes and aged 75 and older who were taking annual health check-up and receiving paper-based medical examination reports at Peking Union Medical College Hospital were enrolled into this study. The patients were randomly divided into two groups (control group and study group). All patients received annual health check-up between November 2014 and October 2015 (baseline health check-up). Patients in control group were given paper-based feedback as usual, while those in study group received feedback via face-to-face or telephone conversations. All patients received their second annual health check-up between November 2015 and October 2016. The patients' blood glucose and weight at the second health check-up were compared between the two groups. Results In baseline health check-up, the levels of HbA1c and BMI showed no difference between the two groups. In the second health check-up, HbA1c and BMI of study group were lower than control group[(7.17±0.58)% vs. (7.44±0.72)%, P=0.027; (24.3±3.8)kg/m2vs. (25.0±4.2)kg/m2,P=0.049]. Fast blood glucose and waist circumference showed no difference between the two groups. Conclusions Combination of paper-based reports and face-to-face or telephone conversations to feedback on health check-up results led to better blood glucose and BMI control in old aged type 2 diabetes patients. HCFS is of vital importance. Key words: Diabetes mellitus, type 2; Blood glucose; Body weight; Health check-up
{"title":"Effects of health check-up feedback style (HCFS) on blood glucose and weight in type 2 diabetes patients aged 75 years and older: a randomized controlled study","authors":"Ya Li, Lingling Jiao, Naishi Li, Zhenjie Wang, Hong Jiang, K. Yu","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.002","url":null,"abstract":"Objective \u0000To analyze the effect of health check-up feedback style (HCFS) on the blood glucose level and weight of type 2 diabetes patients aged 75 years and older. \u0000 \u0000 \u0000Methods \u0000120 consecutive patients with type 2 diabetes and aged 75 and older who were taking annual health check-up and receiving paper-based medical examination reports at Peking Union Medical College Hospital were enrolled into this study. The patients were randomly divided into two groups (control group and study group). All patients received annual health check-up between November 2014 and October 2015 (baseline health check-up). Patients in control group were given paper-based feedback as usual, while those in study group received feedback via face-to-face or telephone conversations. All patients received their second annual health check-up between November 2015 and October 2016. The patients' blood glucose and weight at the second health check-up were compared between the two groups. \u0000 \u0000 \u0000Results \u0000In baseline health check-up, the levels of HbA1c and BMI showed no difference between the two groups. In the second health check-up, HbA1c and BMI of study group were lower than control group[(7.17±0.58)% vs. (7.44±0.72)%, P=0.027; (24.3±3.8)kg/m2vs. (25.0±4.2)kg/m2,P=0.049]. Fast blood glucose and waist circumference showed no difference between the two groups. \u0000 \u0000 \u0000Conclusions \u0000Combination of paper-based reports and face-to-face or telephone conversations to feedback on health check-up results led to better blood glucose and BMI control in old aged type 2 diabetes patients. HCFS is of vital importance. \u0000 \u0000 \u0000Key words: \u0000Diabetes mellitus, type 2; Blood glucose; Body weight; Health check-up","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"74-77"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41656748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-04-30DOI: 10.3760/CMA.J.ISSN.1674-635X.2018.02.007
Xiaozhen Cai, Jian-hua Huang, Hai-Huan Zeng, Xuejuan Wang
Objective To investigate the effect of glutamine (GLN) treatment on neurobehavioral outcome, brain edema and inflammatory response in rats after traumatic brain injury (TBI), and to find out the role played by autophagic response in this effect. Methods Rat models with TBI in this study were established using Feeney's method. One hundred healthy male SD rats were randomly divided into five groups (n=20) to receive sham operation (group Sham), TBI (group TBI), TBI and glutamine treatment (group TBI+ GLN), TBI amd autophagy inhibitor 3-methyladenine (group TBI+ 3-MA), and TBI, GLN and autophagy inhibitor (group TBI+ GLN+ 3-MA). We measured the rats' behavioral outcomes by modified neurologic severity score (mNSS) tests at day 1, 3, 7 and 14 after intervention. Brain water content was measured with wet-dry weight method. The serum levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-1 and IL-4 were tested using enzyme linked immunosorbent assay. The expressions of autophagy-related factors (LC3-Ⅱ, Beclin-1) in TBI cerebral cortex were tested with Western blot. Results Compared with the Sham group, the other four groups had significantly increased levels of brain edema, mNSS, serum inflammatory factors and cerebral LC3-Ⅱ and Beclin-1 (P=0.00). Compared with the TBI group, the TBI+ GLN group had less severe brain edema and improved mNSS, lower levels of TNF-α [(57.71±9.69)pg/ml vs. (83.37±12.81)pg/ml, P=0.01] and IL-1 [(39.46±8.60)pg/ml vs. (69.04±10.48)pg/ml, P=0.00], higher levels of IL-4 [(68.72±11.18)pg/ml vs. (35.75±8.40)pg/ml, P=0.04], and upregulated expressions of LC3-Ⅱ and Beclin-1 (P=0.01). Compared with the TBI+ GLN group, the TBI+ GLN+ 3-MA group had severer neurofunctional impairment, brain edema and inflammation (P<0.05). Conclusions Treatment with GLN markedly reduced brain edema and improved neurobehavioral outcomes in rats with TBI by inhibiting inflammatory response in the central nervous system. The mechanism might have been the activation of the autophagic response. Key words: Traumatic brain injury; Glutamine; Inflammation; Autophagy; Neuroprotection
{"title":"Role of autophagic response in glutamine treatment attenuating inflammation in rats after traumatic brain injury","authors":"Xiaozhen Cai, Jian-hua Huang, Hai-Huan Zeng, Xuejuan Wang","doi":"10.3760/CMA.J.ISSN.1674-635X.2018.02.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2018.02.007","url":null,"abstract":"Objective \u0000To investigate the effect of glutamine (GLN) treatment on neurobehavioral outcome, brain edema and inflammatory response in rats after traumatic brain injury (TBI), and to find out the role played by autophagic response in this effect. \u0000 \u0000 \u0000Methods \u0000Rat models with TBI in this study were established using Feeney's method. One hundred healthy male SD rats were randomly divided into five groups (n=20) to receive sham operation (group Sham), TBI (group TBI), TBI and glutamine treatment (group TBI+ GLN), TBI amd autophagy inhibitor 3-methyladenine (group TBI+ 3-MA), and TBI, GLN and autophagy inhibitor (group TBI+ GLN+ 3-MA). We measured the rats' behavioral outcomes by modified neurologic severity score (mNSS) tests at day 1, 3, 7 and 14 after intervention. Brain water content was measured with wet-dry weight method. The serum levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-1 and IL-4 were tested using enzyme linked immunosorbent assay. The expressions of autophagy-related factors (LC3-Ⅱ, Beclin-1) in TBI cerebral cortex were tested with Western blot. \u0000 \u0000 \u0000Results \u0000Compared with the Sham group, the other four groups had significantly increased levels of brain edema, mNSS, serum inflammatory factors and cerebral LC3-Ⅱ and Beclin-1 (P=0.00). Compared with the TBI group, the TBI+ GLN group had less severe brain edema and improved mNSS, lower levels of TNF-α [(57.71±9.69)pg/ml vs. (83.37±12.81)pg/ml, P=0.01] and IL-1 [(39.46±8.60)pg/ml vs. (69.04±10.48)pg/ml, P=0.00], higher levels of IL-4 [(68.72±11.18)pg/ml vs. (35.75±8.40)pg/ml, P=0.04], and upregulated expressions of LC3-Ⅱ and Beclin-1 (P=0.01). Compared with the TBI+ GLN group, the TBI+ GLN+ 3-MA group had severer neurofunctional impairment, brain edema and inflammation (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Treatment with GLN markedly reduced brain edema and improved neurobehavioral outcomes in rats with TBI by inhibiting inflammatory response in the central nervous system. The mechanism might have been the activation of the autophagic response. \u0000 \u0000 \u0000Key words: \u0000Traumatic brain injury; Glutamine; Inflammation; Autophagy; Neuroprotection","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"26 1","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2018-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69987631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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