Pub Date : 2024-12-13DOI: 10.1080/10286020.2024.2435992
Pei-You Ren, Jian-Ying Zhang, Lei Zhao, Xiang-Jun Sun
Tripterygium wilfordii polyglycoside tablets (TWPT) have traditionally been used to treat certain inflammatory diseases. This study validated TWPT as a novel application in hepatocellular carcinoma treatment through multiple targets, thereby expanding its clinical medication scope. TWPT exhibited a low toxicity and a significantly antihepatoma effects in vitro and in vivo. Through network pharmacology analysis, we found TWPT attenuated the progression of hepatocellular carcinoma by multi-targeting, including IL-6, MMP9, TNF-α and VEGFA. Additionally, TWPT targeted IL-6 to regulate downstream pathways, including the PI3K/Akt, JAK2/STAT3, and MAPK signaling pathways. Thus, TWPT could be developed as a potential therapeutic drug for hepatocellular carcinoma.
{"title":"<i>Tripterygium wilfordii</i> polyglycoside tablets attenuated the progression of hepatocellular carcinoma by targeting IL-6 and downstream signaling pathways in a multi-target manner.","authors":"Pei-You Ren, Jian-Ying Zhang, Lei Zhao, Xiang-Jun Sun","doi":"10.1080/10286020.2024.2435992","DOIUrl":"https://doi.org/10.1080/10286020.2024.2435992","url":null,"abstract":"<p><p><i>Tripterygium wilfordii</i> polyglycoside tablets (TWPT) have traditionally been used to treat certain inflammatory diseases. This study validated TWPT as a novel application in hepatocellular carcinoma treatment through multiple targets, thereby expanding its clinical medication scope. TWPT exhibited a low toxicity and a significantly antihepatoma effects <i>in vitro</i> and <i>in vivo</i>. Through network pharmacology analysis, we found TWPT attenuated the progression of hepatocellular carcinoma by multi-targeting, including IL-6, MMP9, TNF-α and VEGFA. Additionally, TWPT targeted IL-6 to regulate downstream pathways, including the PI3K/Akt, JAK2/STAT3, and MAPK signaling pathways. Thus, TWPT could be developed as a potential therapeutic drug for hepatocellular carcinoma.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":" ","pages":"1-21"},"PeriodicalIF":1.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dazhu Hongjingtian (DZ) is renowned for its diverse pharmacological activities, yet its metabolic pathways remain to be fully elucidated. In this study, the metabolic profile after oral administration of DZ extract (DZE) in rats was systematically identified by the UPLC/Q-TOF-MS/MS method for the first time. A total of 94 components, including 32 prototypes and 62 metabolites, were tentatively characterized in rat plasma and various tissues samples. Furthermore, 6 constituents (salidroside, quercetin, 4-hydroxycinnamic acid, 5-hydroxymethylfurfural, p-tyrosol, and gallic acid) derived from plasma prototypes were identified as bioactive by assessing cell viabilities of OGD-injured RSC96 cells.
{"title":"Characterization of metabolic profile of Dazhu Hongjingtian and evaluation of its anti-hypoxic constituents.","authors":"Chun-Yan Ou, Xia Gao, Jia-Jia Wang, Xia-Lin Chen, Liang Cao, Zhen-Zhong Wang, Chen-Feng Zhang, Wei Xiao","doi":"10.1080/10286020.2024.2434550","DOIUrl":"https://doi.org/10.1080/10286020.2024.2434550","url":null,"abstract":"<p><p>Dazhu Hongjingtian (DZ) is renowned for its diverse pharmacological activities, yet its metabolic pathways remain to be fully elucidated. In this study, the metabolic profile after oral administration of DZ extract (DZE) in rats was systematically identified by the UPLC/Q-TOF-MS/MS method for the first time. A total of 94 components, including 32 prototypes and 62 metabolites, were tentatively characterized in rat plasma and various tissues samples. Furthermore, 6 constituents (salidroside, quercetin, 4-hydroxycinnamic acid, 5-hydroxymethylfurfural, <i>p</i>-tyrosol, and gallic acid) derived from plasma prototypes were identified as bioactive by assessing cell viabilities of OGD-injured RSC96 cells.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":" ","pages":"1-19"},"PeriodicalIF":1.3,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-03DOI: 10.1080/10286020.2024.2434564
Le Thi Vien, Tran Thi Hong Hanh, Tran Hong Quang, Nguyen Dang Ngai, Dao Viet Ha, Nguyen Xuan Cuong
Using various chromatographic separations, six steroid glycoside derivatives, including one new compound named culcinoside E (1), were isolated from the methanol extract of the starfish Culcita novaeguineae. Their structures were confirmed by detailed analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. Among isolated compounds, culcinoside E (1), diplasterioside A (5), and thornasteroside A (6) inhibited growth of Enterococcus faecalis, whereas culcitoside C1 (3) was active on Candida albicans.
{"title":"Culcinoside E, a new sulfated steroidal biglycoside from the starfish <i>Culcita novaeguineae</i>.","authors":"Le Thi Vien, Tran Thi Hong Hanh, Tran Hong Quang, Nguyen Dang Ngai, Dao Viet Ha, Nguyen Xuan Cuong","doi":"10.1080/10286020.2024.2434564","DOIUrl":"https://doi.org/10.1080/10286020.2024.2434564","url":null,"abstract":"<p><p>Using various chromatographic separations, six steroid glycoside derivatives, including one new compound named culcinoside E (<b>1</b>), were isolated from the methanol extract of the starfish <i>Culcita novaeguineae</i>. Their structures were confirmed by detailed analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. Among isolated compounds, culcinoside E (<b>1</b>), diplasterioside A (<b>5</b>), and thornasteroside A (<b>6</b>) inhibited growth of <i>Enterococcus faecalis</i>, whereas culcitoside C<sub>1</sub> (<b>3</b>) was active on <i>Candida albicans</i>.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":" ","pages":"1-7"},"PeriodicalIF":1.3,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142768182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2368835
ST Shukla , Anu Kaushik , Samiullah Allahbaksh Auti , Dinesh Kumar , Supriya Kumar Das
This study investigated the effects of halibut oil cream, containing omega-3 fatty acids, vitamins A and D, and hydroxyproline, on burn wound healing in rats. Acute dermal toxicity tests confirmed its nontoxicity. Wistar rats were divided into five groups: a control, a positive control treated with silver sulfadiazine 1% (SSD), and three groups treated with 3%, 9%, and 27% halibut oil cream Formulation (HBOF). The SSD and HBOF groups showed significant healing improvements compared to the control. Histopathological analysis indicated increased collagen production in the HBOF groups, suggesting halibut oil cream’s potential as a topical treatment for burn wounds.
本研究调查了含有欧米茄-3 脂肪酸、维生素 A 和 D 以及羟脯氨酸的比目鱼油膏对大鼠烧伤伤口愈合的影响。急性皮肤毒性试验证实其无毒性。Wistar 大鼠被分为五组：一组为对照组，一组为使用 1%磺胺嘧啶银（SSD）治疗的阳性对照组，三组分别使用 3%、9% 和 27% 的大比目鱼油膏配方（HBOF）治疗。与对照组相比，磺胺嘧啶银组和比目鱼油膏组的愈合效果显著。组织病理学分析表明，HBOF 组的胶原蛋白生成增加，这表明大比目鱼油膏具有局部治疗烧伤创面的潜力。
{"title":"Preclinical determination of wound-healing activity of halibut oil cream in rat model of burn wound","authors":"ST Shukla , Anu Kaushik , Samiullah Allahbaksh Auti , Dinesh Kumar , Supriya Kumar Das","doi":"10.1080/10286020.2024.2368835","DOIUrl":"10.1080/10286020.2024.2368835","url":null,"abstract":"<div><div>This study investigated the effects of halibut oil cream, containing omega-3 fatty acids, vitamins A and D, and hydroxyproline, on burn wound healing in rats. Acute dermal toxicity tests confirmed its nontoxicity. Wistar rats were divided into five groups: a control, a positive control treated with silver sulfadiazine 1% (SSD), and three groups treated with 3%, 9%, and 27% halibut oil cream Formulation (HBOF). The SSD and HBOF groups showed significant healing improvements compared to the control. Histopathological analysis indicated increased collagen production in the HBOF groups, suggesting halibut oil cream’s potential as a topical treatment for burn wounds.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1455-1474"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2371032
Cai-Wen Fan , Li Luo , Mei-Shan Li , Yun-Qiong Gu , Yi-Lin Fang , Feng Qin , Heng-Shan Wang
Sesquilignans PD is a natural phenylpropanoid compound that was isolated from Zanthoxylum nitidum var. tomentosum. In this study, we assessed the antitumor effect of PD on SK-Hep-1 and HepG2 cells and the underlying molecular mechanisms. The results revealed that PD markedly inhibited the proliferation and migration of both liver cancer cells. Moreover, PD induced apoptosis, autophagy, and reactive oxygen species (ROS) production in liver cancer cells. Notably, PD increased the protein levels of p-p38 MAPK and p-ERK1/2 in liver cancer cells. This is the first report on the anticancer effect of PD, which is mediated via increased ROS production and MAPK signaling activation.
{"title":"Sesquilignans PD from Zanthoxylum nitidum var. tomentosum exerts antitumor effects via the ROS/MAPK pathway in liver cancer cells","authors":"Cai-Wen Fan , Li Luo , Mei-Shan Li , Yun-Qiong Gu , Yi-Lin Fang , Feng Qin , Heng-Shan Wang","doi":"10.1080/10286020.2024.2371032","DOIUrl":"10.1080/10286020.2024.2371032","url":null,"abstract":"<div><div>Sesquilignans <strong>PD</strong> is a natural phenylpropanoid compound that was isolated from <em>Zanthoxylum nitidum</em> var. <em>tomentosum</em>. In this study, we assessed the antitumor effect of <strong>PD</strong> on SK-Hep-1 and HepG2 cells and the underlying molecular mechanisms. The results revealed that <strong>PD</strong> markedly inhibited the proliferation and migration of both liver cancer cells. Moreover, <strong>PD</strong> induced apoptosis, autophagy, and reactive oxygen species (ROS) production in liver cancer cells. Notably, <strong>PD</strong> increased the protein levels of p-p38 MAPK and p-ERK1/2 in liver cancer cells. This is the first report on the anticancer effect of <strong>PD</strong>, which is mediated <em>via</em> increased ROS production and MAPK signaling activation.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1530-1542"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141492125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2366010
Zhao Zhai , Jie Fu , Meng-Liang Ye , Jing-Yue Wang , Hao-Jian Zhang , Hang Yu , Xin-Yu Yang , Hui Xu , Jia-Chun Hu , Jin-Yue Lu , Heng-Tong Zuo , Yi Zhao , Jian-Ye Song , Yong Zhang , Yan Wang , Nian-Zeng Xing
Liquiritigenin is a natural medicine. However, its inhibitory effect and its potential mechanism on bladder cancer (BCa) remain to be explored. It was found that it could be visualized that the transplanted tumours in the low-dose liquiritigenin -treated group and the high-dose liquiritigenin -treated group were smaller than those in the model group. Liquiritigenin treatment led to alterations in Lachnoclostridium, Escherichia-Shigella, Alistipes and Akkermansia. Non-targeted metabolomics analysis showed that a total of multiple differential metabolites were identified between the model group and the high-dose liquiritigenin-treated group. This provides a new direction and rationale for the antitumour effects of liquiritigenin.
{"title":"The changes of intestinal microbiota and metabolomics during the inhibition of bladder cancer by liquiritigenin","authors":"Zhao Zhai , Jie Fu , Meng-Liang Ye , Jing-Yue Wang , Hao-Jian Zhang , Hang Yu , Xin-Yu Yang , Hui Xu , Jia-Chun Hu , Jin-Yue Lu , Heng-Tong Zuo , Yi Zhao , Jian-Ye Song , Yong Zhang , Yan Wang , Nian-Zeng Xing","doi":"10.1080/10286020.2024.2366010","DOIUrl":"10.1080/10286020.2024.2366010","url":null,"abstract":"<div><div>Liquiritigenin is a natural medicine. However, its inhibitory effect and its potential mechanism on bladder cancer (BCa) remain to be explored. It was found that it could be visualized that the transplanted tumours in the low-dose liquiritigenin -treated group and the high-dose liquiritigenin -treated group were smaller than those in the model group. Liquiritigenin treatment led to alterations in Lachnoclostridium, <em>Escherichia-Shigella, Alistipes</em> and <em>Akkermansia</em>. Non-targeted metabolomics analysis showed that a total of multiple differential metabolites were identified between the model group and the high-dose liquiritigenin-treated group. This provides a new direction and rationale for the antitumour effects of liquiritigenin.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1445-1454"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The undescribed phosphatidylcholine (1), along with twelve known compounds, was isolated from the cultures of white rot fungus Microporus xanthropus PP17-20. In this work the fungus was cultivated in Yeast-Malt extract medium to explore active compound production. The chemical structures were elucidated on the basis of spectroscopic and HRESIMS data. Several isolated compounds were evaluated for anti-proliferative activity against A549 and MCF-7 cancer cell lines.
{"title":"Phosphatidylcholine and ceramide derivatives from white rot fungus Microporus xanthropus PP17-20","authors":"Phongphan Jantaharn , Audomsak Churat , Sirirat Juanan , Ek Sangvichien , Wiyada Mongkolthanaruk , Nuttika Suwannasai , Thanaset Senawong , Sirirath McCloskey","doi":"10.1080/10286020.2024.2368834","DOIUrl":"10.1080/10286020.2024.2368834","url":null,"abstract":"<div><div>The undescribed phosphatidylcholine (<strong>1</strong>), along with twelve known compounds, was isolated from the cultures of white rot fungus <em>Microporus xanthropus</em> PP17-20. In this work the fungus was cultivated in Yeast-Malt extract medium to explore active compound production. The chemical structures were elucidated on the basis of spectroscopic and HRESIMS data. Several isolated compounds were evaluated for anti-proliferative activity against A549 and MCF-7 cancer cell lines.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1551-1556"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141468155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2370401
Xian-Sheng Ye , Kuan Lin , Chang-Long Leng , Yu-Ran Gui , Shu-Xiu Zhu , Hui-Ying Liu , Yi-Yuan Xia , Bin-Lian Sun , Wei Liu , Xi-Ji Shu
The preliminary study revealed that the ethyl acetate eluate of Youngia japonica (YJ-E) could inhibit the expression of key proteins of p-p65, p-IκBα, p-IKKα/β, and p-AKT in LPS stimulated BV2 cell. Further phytochemical study led to the isolation of eight compounds from YJ-E, including one new sesquiterpene lactone. Their structures were elucidated by several spectroscopic data, and comparing the NMR data of known compound. In addition, all of the isolates were evaluated for the anti-inflammatory effect. As a result, compounds 3 and 4 distinctly attenuated the expressions of p-IκBα, p-p65, and p-AKT in LPS stimulated BV2 cell, respectively.
{"title":"Discovery of sesquiterpene lactones with anti-inflammatory effect from Youngia japonica","authors":"Xian-Sheng Ye , Kuan Lin , Chang-Long Leng , Yu-Ran Gui , Shu-Xiu Zhu , Hui-Ying Liu , Yi-Yuan Xia , Bin-Lian Sun , Wei Liu , Xi-Ji Shu","doi":"10.1080/10286020.2024.2370401","DOIUrl":"10.1080/10286020.2024.2370401","url":null,"abstract":"<div><div>The preliminary study revealed that the ethyl acetate eluate of <em>Youngia japonica</em> (YJ-E) could inhibit the expression of key proteins of p-p65, p-IκBα, p-IKKα/β, and p-AKT in LPS stimulated BV2 cell. Further phytochemical study led to the isolation of eight compounds from YJ-E, including one new sesquiterpene lactone. Their structures were elucidated by several spectroscopic data, and comparing the NMR data of known compound. In addition, all of the isolates were evaluated for the anti-inflammatory effect. As a result, compounds <strong>3</strong> and <strong>4</strong> distinctly attenuated the expressions of p-IκBα, p-p65, and p-AKT in LPS stimulated BV2 cell, respectively.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1557-1564"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141498137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2369279
Da-Min Jung , Sangsoo Lee , Eun-Mi Kim , Chong Won Choi , Kee K. Kim
Inhibition of lipid synthesis in sebocytes is essential for acne treatments. The effects of natural product-derived substances on lipid synthesis are unknown. This study investigated the effects of water extract of Mangifera indica leaves (WEML) on lipid synthesis in human sebocytes. Sebocyte differentiation in low serum conditions increased lipid accumulation and proliferator-activated receptor γ expression. WEML treatment significantly inhibited lipid accumulation and adipogenic mRNA expression in sebocytes. Mangiferin, a bioactive compound in WEML, also reduced lipid accumulation and adipogenic mRNA expression via the AKT pathway. Thus, WEML and mangiferin effectively inhibit lipid synthesis in sebocytes, showing promise for acne treatment.
{"title":"Mangiferin, a component of Mangifera indica leaf extracts, inhibits lipid synthesis in human sebocytes","authors":"Da-Min Jung , Sangsoo Lee , Eun-Mi Kim , Chong Won Choi , Kee K. Kim","doi":"10.1080/10286020.2024.2369279","DOIUrl":"10.1080/10286020.2024.2369279","url":null,"abstract":"<div><div>Inhibition of lipid synthesis in sebocytes is essential for acne treatments. The effects of natural product-derived substances on lipid synthesis are unknown. This study investigated the effects of water extract of <em>Mangifera indica</em> leaves (WEML) on lipid synthesis in human sebocytes. Sebocyte differentiation in low serum conditions increased lipid accumulation and proliferator-activated receptor γ expression. WEML treatment significantly inhibited lipid accumulation and adipogenic mRNA expression in sebocytes. Mangiferin, a bioactive compound in WEML, also reduced lipid accumulation and adipogenic mRNA expression via the AKT pathway. Thus, WEML and mangiferin effectively inhibit lipid synthesis in sebocytes, showing promise for acne treatment.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1489-1501"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1080/10286020.2024.2412762
Yan-Fei Liu , Shi-Shan Yu
The new natural products reported in 2023 in peer-reviewed articles in journals with good reputations were reviewed and analyzed. The advances made by Asian research groups in the field of natural products chemistry in 2023 were summarized. Compounds with unique structural features and/or promising bioactivities originating from Asian natural sources were discussed based on their structural classification.
{"title":"Survey of natural products reported by Asian research groups in 2023","authors":"Yan-Fei Liu , Shi-Shan Yu","doi":"10.1080/10286020.2024.2412762","DOIUrl":"10.1080/10286020.2024.2412762","url":null,"abstract":"<div><div>The new natural products reported in 2023 in peer-reviewed articles in journals with good reputations were reviewed and analyzed. The advances made by Asian research groups in the field of natural products chemistry in 2023 were summarized. Compounds with unique structural features and/or promising bioactivities originating from Asian natural sources were discussed based on their structural classification.</div></div>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":"26 12","pages":"Pages 1389-1404"},"PeriodicalIF":1.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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