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Piezoelectric MEMS microphones based on rib structures and single crystal PZT thin film. 基于肋条结构和单晶 PZT 薄膜的压电 MEMS 麦克风。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-08 DOI: 10.1038/s41378-024-00767-5
Zhiwei You, Jinghan Gan, Chong Yang, Renati Tuerhong, Lei Zhao, Yipeng Lu

In this study, a controllable mass‒frequency tuning method is presented using the etching of rib structures on a single-crystal PZT membrane. The rib structures were optimized to reduce the membrane mass while maintaining the stiffness; therefore, the center frequency could be increased to improve the low-frequency bandwidth of microphones. Additionally, this methodology could reduce the modulus and improve the sensitivity for the same resonant frequency, which typically indicates the maximum acoustic overload point (AOP). The PZT film was chosen because of its greater density; the simulation results showed that PZT could provide a greater frequency tuning (24.9%) compared to that of the AlN film (5.8%), and its large dielectric constant enabled the optimal design to have small electrodes at the maximum stress location while mitigating the sacrificial capacitance effect on electrical gain. An analytical model of rib-structure microphones was established and greatly reduced the computing time. The experimental results of the impedance tests revealed that the center frequencies of the six microphones shifted from 74.6 kHz to 106.3 kHz with rib-structure inner radii ranging from 0 μm to 340 μm; this result was in good agreement with the those of the analytical analysis and finite element modeling. While the center frequency greatly varied, the measured sensitivities at 1 kHz only varied within a small range from 22.3 mV/Pa to 25.7 mV/Pa; thus, the membrane stiffness minimally changed. Moreover, a single-crystal PZT film with a (100) crystal orientation and 0.24-degree full width at half maximum (FWHM) was used to enable differential sensing and a low possibility of undesirable polarization. Paired with a two-stage differential charge amplifier, a differential sensing microphone was experimentally demonstrated to improve the sensitivity from 25.7 mV/Pa to 36.1 mV/Pa and reduce the noise from -68.2 dBV to -82.8 dBV.

本研究提出了一种可控的质量-频率调谐方法,即在单晶 PZT 膜上蚀刻肋条结构。对肋条结构进行了优化,以在保持刚度的同时降低膜质量;因此,中心频率可以提高,从而改善麦克风的低频带宽。此外,这种方法还能降低模量,提高相同共振频率下的灵敏度,该频率通常表示最大声学过载点(AOP)。选择 PZT 薄膜是因为它的密度更大;模拟结果表明,与 AlN 薄膜(5.8%)相比,PZT 可以提供更大的频率调谐(24.9%),而且它的大介电常数使得最佳设计可以在最大应力位置使用小电极,同时减轻牺牲电容对电气增益的影响。建立了肋骨结构麦克风的分析模型,大大缩短了计算时间。阻抗测试的实验结果表明,当肋骨结构的内半径从 0 μm 到 340 μm 时,六个传声器的中心频率从 74.6 kHz 到 106.3 kHz 不等;这一结果与分析和有限元建模的结果十分吻合。虽然中心频率变化很大,但在 1 kHz 时测得的灵敏度仅在 22.3 mV/Pa 至 25.7 mV/Pa 的较小范围内变化,因此膜刚度的变化很小。此外,还使用了晶体取向为(100)、半最大全宽(FWHM)为 0.24 度的单晶 PZT 薄膜,以实现差分传感,并降低不良极化的可能性。实验证明,与两级差分电荷放大器搭配使用的差分传感麦克风可将灵敏度从 25.7 mV/Pa 提高到 36.1 mV/Pa,并将噪声从 -68.2 dBV 降低到 -82.8 dBV。
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引用次数: 0
Biomimetic hair-assisted GaN optical devices for bidirectional airflow detection. 用于双向气流检测的仿生毛发辅助氮化镓光学器件。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-08 DOI: 10.1038/s41378-024-00794-2
Tianyu Ye, Jian Chen, Xinke Tang, Kwai Hei Li

Airflow sensing plays a pivotal role in numerous fields, including medicine, industry, and environmental monitoring. However, detecting bidirectional airflow using a single sensing unit poses significant challenges. In this work, a miniature airflow sensing device is introduced, utilizing a GaN optical chip integrated with a biomimetic hair structure. The sensing device comprises a monolithic GaN chip that handles both light emission and detection. The biomimetic hairs, constructed from nylon fibers and PDMS film, undergo structural bending in converting airflow signals into optical changes, modulating the light captured by the on-chip detector. The intensity of the airflow directly correlates with the bending extent of the biomimetic hair, facilitating the precise detection of airflow rates through changes in the photocurrent. The integrated device can measure a wide range of airflow rates from -23.87 ms-1 to 21.29 ms-1, and exhibit a rapid response time of 13 ms and a detection limit of 0.1 ms-1. Characterized by its compact size, fast response time, and bidirectional detection ability, the developed device holds immense potential for applications in breath detection, speech recognition, encoding information, and the realization of logic operations.

气流感应在医疗、工业和环境监测等众多领域发挥着举足轻重的作用。然而,使用单个传感装置检测双向气流是一项重大挑战。在这项工作中,我们介绍了一种微型气流传感装置,它采用了一种与仿生物毛发结构集成的氮化镓光学芯片。该传感装置由单片式氮化镓芯片组成,可同时处理光发射和检测。仿生毛发由尼龙纤维和 PDMS 薄膜构成,在将气流信号转换为光学变化的过程中会发生结构弯曲,从而调节芯片上探测器捕捉到的光线。气流强度与仿生毛发的弯曲程度直接相关,有助于通过光电流的变化精确检测气流速率。该集成装置可测量 -23.87 ms-1 至 21.29 ms-1 的大范围气流速率,快速响应时间为 13 ms,检测限为 0.1 ms-1。所开发的装置具有体积小、响应时间快和双向检测能力强等特点,在呼吸检测、语音识别、信息编码和实现逻辑运算等方面具有巨大的应用潜力。
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引用次数: 0
Deep learning-assisted object recognition with hybrid triboelectric-capacitive tactile sensor. 利用混合三电电容式触觉传感器进行深度学习辅助物体识别。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-07 DOI: 10.1038/s41378-024-00813-2
Yating Xie, Hongyu Cheng, Chaocheng Yuan, Limin Zheng, Zhengchun Peng, Bo Meng

Tactile sensors play a critical role in robotic intelligence and human-machine interaction. In this manuscript, we propose a hybrid tactile sensor by integrating a triboelectric sensing unit and a capacitive sensing unit based on porous PDMS. The triboelectric sensing unit is sensitive to the surface material and texture of the grasped objects, while the capacitive sensing unit responds to the object's hardness. By combining signals from the two sensing units, tactile object recognition can be achieved among not only different objects but also the same object in different states. In addition, both the triboelectric layer and the capacitor dielectric layer were fabricated through the same manufacturing process. Furthermore, deep learning was employed to assist the tactile sensor in accurate object recognition. As a demonstration, the identification of 12 samples was implemented using this hybrid tactile sensor, and an recognition accuracy of 98.46% was achieved. Overall, the proposed hybrid tactile sensor has shown great potential in robotic perception and tactile intelligence.

触觉传感器在机器人智能和人机交互中发挥着至关重要的作用。在本手稿中,我们提出了一种混合触觉传感器,它集成了一个三电传感单元和一个基于多孔 PDMS 的电容传感单元。三电传感单元对所抓物体的表面材料和纹理敏感,而电容传感单元则对物体的硬度做出反应。通过组合两个传感单元的信号,不仅可以识别不同的物体,还可以识别处于不同状态的同一物体。此外,三电层和电容器介电层都是通过相同的制造工艺制造的。此外,还采用了深度学习技术来辅助触觉传感器准确识别物体。作为演示,使用该混合触觉传感器对 12 个样本进行了识别,识别准确率达到 98.46%。总之,所提出的混合触觉传感器在机器人感知和触觉智能方面展现出了巨大的潜力。
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引用次数: 0
Real-time correction of gain nonlinearity in electrostatic actuation for whole-angle micro-shell resonator gyroscope. 全角微壳共振陀螺仪静电驱动增益非线性实时校正。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-05 DOI: 10.1038/s41378-024-00818-x
Sheng Yu, Jiangkun Sun, Yongmeng Zhang, Xiang Xi, Kun Lu, Yan Shi, Dingbang Xiao, Xuezhong Wu

MEMS gyroscopes are well known for their outstanding advantages in Cost Size Weight and Power (CSWaP), which have inspired great research attention in recent years. A higher signal-to-noise ratio (SNR) for MEMS gyroscopes operating at larger vibrating amplitudes provides improved measuring resolution and ARW performance. However, the increment of amplitude causes strong nonlinear effects of MEMS gyroscopes due to their micron size, which has negative influences on the performance. This paper carries out detailed research on a general nonlinear mechanism on the sensors using parallel-plate capacitive transducers, which is called the gain nonlinearity in electrostatic actuation. The theoretical model established in this paper demonstrates the actuation gain nonlinearity causes the control-force coupling and brings extra angle-dependent bias with the 4th component for the whole-angle gyroscopes, which are verified by the experiments carried out on a micro-shell resonator gyroscope (MSRG). Furthermore, a real-time correction method is proposed to restore a linear response of the electrostatic actuation, which is realized by the gain modification with an online parameter estimation based on the harmonic-component relationship of capacitive detection. This real-time correction method could reduce the 4th component of the angle-dependent bias by over 95% from 0.003°/s to less than 0.0001°/s even under different temperatures. After the correction of actuation gain nonlinearity, the bias instability (BI) of whole-angle MSRG is improved by about 3.5 times from 0.101°/h to 0.029°/h and the scale factor nonlinearity (SFN) is reduced by almost one order of magnitude from 2.02 ppm to 0.21 ppm.

众所周知,MEMS 陀螺仪在成本、尺寸、重量和功耗(CSWaP)方面具有突出优势,近年来引起了研究人员的极大关注。在更大振动振幅下工作的 MEMS 陀螺仪具有更高的信噪比(SNR),从而提高了测量分辨率和 ARW 性能。然而,由于 MEMS 陀螺仪的微米尺寸,振幅的增大会对其产生强烈的非线性效应,从而对其性能产生负面影响。本文详细研究了使用平行板电容式传感器的传感器的一般非线性机制,即静电致动中的增益非线性。本文建立的理论模型证明了致动增益非线性会导致控制力耦合,并为全角度陀螺仪带来与角度相关的第四分量额外偏差,这一点已通过在微壳谐振器陀螺仪(MSRG)上进行的实验得到验证。此外,还提出了一种恢复静电致动线性响应的实时校正方法,该方法通过增益修正和基于电容检测谐波分量关系的在线参数估计来实现。即使在不同的温度条件下,这种实时修正方法也能将与角度有关的偏差的第 4 分量从 0.003°/s 降至 0.0001°/s 以下,降幅超过 95%。在修正了致动增益非线性之后,全角度 MSRG 的偏置不稳定性 (BI) 从 0.101°/h 降至 0.029°/h,提高了约 3.5 倍,比例因子非线性 (SFN) 从 2.02 ppm 降至 0.21 ppm,降低了近一个数量级。
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引用次数: 0
High-density, high-frequency and large-scale electrohydrodynamic drop-on-demand jetting via a protruding polymer-based printhead design. 通过基于聚合物的突出式喷头设计,实现高密度、高频率和大规模按需滴电流体动力喷射。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-05 DOI: 10.1038/s41378-024-00786-2
Yongqing Duan, Weili Yang, Qiming Wang, Zhaoyang Sun, Haoyu Guo, Zhouping Yin

Electrohydrodynamic (EHD) printing has critical merits in micro/nanoscale additive manufacturing because of its ultrahigh resolution and wide ink compatibility, making it an advantageous choice for electronics manufacturing, high-resolution prototyping, and biological component fabrication. However, EHD printing is currently limited by its rather low throughput due to the lack of high-frequency and high-density multi-nozzle printheads. This paper presents a novel EHD printhead with a protruding polymer-based nozzle design. An insulated, hydrophobic, and protruding polymer nozzle array with an appropriate geometric structure can effectively address key problems in multi-nozzle jetting, such as electrical crosstalk, electrical discharge, liquid flooding, and nonuniform jetting. By investigating the influence of the electrical and geometric characteristics of the nozzle arrays on the electrical crosstalk behavior and fabricating the optimized nozzle array via MEMS technology, we achieve an EHD printhead with a large scale (256), high density (127 dpi), and high jetting frequency (23 kHz), and addressable jetting can be realized by adding independently controllable extractors underneath the nozzle array. Many functional materials, such as quantum dots, perovskite, and nanosilver inks, can be ejected into high-resolution patterns through the optimized nozzle array, demonstrating the great prospects of our designed printhead in electronics manufacturing. This MEMS-compatible printhead design lays the foundation for high-throughput fabrication of micro/nanostructures and promotes practical applications of EHD printing in functional electronics and biomedical/energy devices.

电流体动力(EHD)打印因其超高的分辨率和广泛的油墨兼容性,在微米/纳米级增材制造领域具有重要优势,是电子制造、高分辨率原型和生物组件制造的有利选择。然而,由于缺乏高频率、高密度的多喷嘴打印头,EHD 打印目前受限于其相当低的吞吐量。本文介绍了一种基于聚合物喷嘴设计的新型 EHD 打印头。具有适当几何结构的绝缘、疏水和突出聚合物喷嘴阵列可有效解决多喷嘴喷射中的关键问题,如电串扰、放电、液体淹没和不均匀喷射。通过研究喷嘴阵列的电气和几何特性对电气串扰行为的影响,并通过 MEMS 技术制造出优化的喷嘴阵列,我们实现了大尺度(256)、高密度(127 dpi)和高喷射频率(23 kHz)的 EHD 喷头,并通过在喷嘴阵列下方添加独立可控的提取器实现了可寻址喷射。许多功能材料,如量子点、过氧化物和纳米银墨水,都可以通过优化的喷嘴阵列喷射出高分辨率图案,这表明我们设计的喷头在电子制造领域具有广阔的应用前景。这种兼容 MEMS 的打印头设计为高通量制造微/纳米结构奠定了基础,并促进了 EHD 打印在功能电子器件和生物医学/能源设备中的实际应用。
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引用次数: 0
Rapid-response, low-detection-limit, positive-negative air pressure sensing: GaN chips integrated with hydrophobic PDMS films. 快速响应、低检测限、正负气压传感:与疏水性 PDMS 薄膜集成的氮化镓芯片。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-11-01 DOI: 10.1038/s41378-024-00766-6
Sizhe Gui, Binlu Yu, Yumeng Luo, Liang Chen, Kwai Hei Li

Despite the importance of positive and negative pressure sensing in numerous domains, the availability of a single sensing unit adept at handling this dual task remains highly limited. This study introduces a compact optical device capable of swiftly and precisely detecting positive and negative pressures ranging from -35 kPa to 35 kPa. The GaN chip, which serves as a core component of the device, is monolithically integrated with light-emitting and light-detecting elements. By combining a deformable PDMS film coated with a hydrophobic layer, the chip can respond to changes in optical reflectance induced by pressure fluctuations. The integrated sensing device has low detection limits of 4.3 Pa and -7.8 Pa and fast response times of 0.14 s and 0.22 s for positive and negative pressure variations, respectively. The device also demonstrates adaptability in capturing distinct human breathing patterns. The proposed device, characterized by its compactness, responsiveness, and ease of operation, holds promise for a variety of pressure-sensing applications.

尽管正负压传感在许多领域都非常重要,但能够胜任这一双重任务的单一传感装置仍然非常有限。本研究介绍了一种紧凑型光学装置,能够快速、精确地检测-35 kPa 至 35 kPa 的正负压。作为该装置核心部件的氮化镓芯片与发光和光检测元件单片集成。通过结合涂有疏水层的可变形 PDMS 薄膜,芯片可以对压力波动引起的光学反射率变化做出响应。该集成传感装置的检测限低至 4.3 Pa 和 -7.8 Pa,对正压和负压变化的快速响应时间分别为 0.14 秒和 0.22 秒。该装置还具有捕捉人类独特呼吸模式的适应性。该设备结构紧凑、反应灵敏、操作简便,有望用于各种压力感应应用。
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引用次数: 0
A microsystem for in vivo wireless monitoring of plastic biliary stents using magnetoelastic sensors. 利用磁弹性传感器对塑料胆道支架进行体内无线监测的微型系统。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-10-31 DOI: 10.1038/s41378-024-00772-8
Ramprasad M Nambisan, Scott R Green, Richard S Kwon, Grace H Elta, Yogesh B Gianchandani

With an interest in monitoring the patency of stents that are used to treat strictures in the bile duct, this paper reports the investigation of a wireless sensing system to interrogate a microsensor integrated into the stent. The microsensor is comprised of a 28-μm-thick magnetoelastic foil with 8.25-mm length and 1-mm width. Magnetic biasing is provided by permanent magnets attached to the foil. These elements are incorporated into a customized 3D polymeric package. The system electromagnetically excites the magnetoelastic resonant sensor and measures the resulting signal. Through shifts in resonant frequency and quality factor, the sensor is intended to provide an early indication of sludge accumulation in the stent. This work focuses on challenges associated with sensor miniaturization and placement, wireless range, drive signal feedthrough, and clinical use. A swine specimen in vivo experiment is described. Following endoscopic implantation of the sensor enabled plastic stent into the bile duct, at a range of approximately 17 cm, the signal-to-noise ratio of ~106 was observed with an interrogation time of 336 s. These are the first reported signals from a passive wireless magnetoelastic sensor implanted in a live animal.

为了监测用于治疗胆管狭窄的支架的通畅性,本文报告了对一种无线传感系统的研究,该系统用于询问集成在支架中的微型传感器。微型传感器由长 8.25 毫米、宽 1 毫米、厚 28 微米的磁弹性箔组成。磁偏压由附着在箔上的永久磁铁提供。这些元件被集成到一个定制的三维聚合物封装中。系统以电磁方式激发磁弹性谐振传感器,并测量由此产生的信号。通过共振频率和品质因数的变化,传感器可及早显示支架中的污泥积聚情况。这项工作的重点是与传感器微型化和放置、无线范围、驱动信号馈通和临床使用相关的挑战。文中描述了一个猪标本体内实验。在内窥镜下将启用传感器的塑料支架植入胆管后,在约 17 厘米的范围内,观察到信噪比约为 106,询问时间为 336 秒。这是首次报道植入活体动物体内的无源无线磁弹性传感器发出的信号。
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引用次数: 0
Machine learning-driven discovery of high-performance MEMS disk resonator gyroscope structural topologies. 机器学习驱动的高性能 MEMS 圆盘谐振器陀螺仪结构拓扑发现。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-10-30 DOI: 10.1038/s41378-024-00792-4
Chen Chen, Jinqiu Zhou, Hongyi Wang, Youyou Fan, Xinyue Song, Jianbing Xie, Thomas Bäck, Hao Wang

The design of the microelectromechanical system (MEMS) disc resonator gyroscope (DRG) structural topology is crucial for its physical properties and performance. However, creating novel high-performance MEMS DRGs has long been viewed as a formidable challenge owing to their enormous design space, the complexity of microscale physical effects, and time-consuming finite element analysis (FEA). Here, we introduce a new machine learning-driven approach to discover high-performance DRG topologies. We represent the DRG topology as pixelated binary matrices and formulate the design task as a path-planning problem. This path-planning problem is solved via deep reinforcement learning (DRL). In addition, we develop a convolutional neural network-based surrogate model to replace the expensive FEA to provide reward signals for DRL training. Benefiting from the computational efficiency of neural networks, our approach achieves a significant acceleration ratio of 4.03 × 105 compared with FEA, reducing each DRL training run to only 426.5 s. Through 8000 training runs, we discovered 7120 novel structural topologies that achieve navigation-grade precision. Many of these surpass traditional designs in performance by several orders of magnitude, revealing innovative solutions previously unconceived by humans.

微机电系统(MEMS)圆盘谐振器陀螺仪(DRG)结构拓扑的设计对其物理性质和性能至关重要。然而,由于设计空间巨大、微尺度物理效应复杂以及有限元分析(FEA)耗时,创造新型高性能 MEMS DRG 长期以来一直被视为一项艰巨的挑战。在这里,我们引入了一种新的机器学习驱动方法来发现高性能 DRG 拓扑。我们将 DRG 拓扑表示为像素化的二进制矩阵,并将设计任务表述为路径规划问题。该路径规划问题通过深度强化学习(DRL)来解决。此外,我们还开发了一种基于卷积神经网络的替代模型,以取代昂贵的有限元分析,为 DRL 训练提供奖励信号。得益于神经网络的计算效率,与有限元分析相比,我们的方法实现了 4.03 × 105 的显著加速比,将每次 DRL 训练运行缩短至 426.5 秒。通过 8000 次训练运行,我们发现了 7120 种达到导航级精度的新型结构拓扑。其中许多设计在性能上超过了传统设计几个数量级,揭示了人类以前从未想到过的创新解决方案。
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引用次数: 0
Bridging piezoelectric and electrostatic effects: a novel piezo-MEMS pitch/roll gyroscope with sub 10°/h bias instability. 压电效应和静电效应的桥梁:具有低于 10°/h 偏置不稳定性的新型压电-MEMS俯仰/滚动陀螺仪。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-10-30 DOI: 10.1038/s41378-024-00773-7
Zhenxiang Qi, Bowen Wang, Zhaoyang Zhai, Zheng Wang, Xingyin Xiong, Wuhao Yang, Xiaorui Bie, Yao Wang, Xudong Zou

This paper proposes a novel piezo-MEMS pitch/roll gyroscope that co-integrates piezoelectric and electrostatic effects, for the first time achieves electrostatic mode-matching operation for piezoelectric gyroscopes. Movement of operated out-of-plane (OOP) mode (n = 3) and in-plane (IP) mode (n = 2) are orthogonal, ensuring that the OOP amplitude is not significantly limited by parallel plates set at nodes of IP mode. Therefore, a large OOP driving amplitude actuated by piezoelectric and frequency tuning in the IP sense mode trimmed by electrostatic can be achieved together with a low risk of pull-in, hence releases the trade-off between the tuning range and the linear actuation range. At a tuning voltage of 66 V, the frequency split decreased from 171 Hz to 0.1 Hz, resulting in a 167x times improvement in sensitivity. The mode-matched gyroscope exhibits an angle random walk (ARW) of 0.41°/√h and a bias instability (BI) of 8.85°/h on a test board within a customized vacuum chamber, marking enhancements of 68x and 301x, respectively, compared to its performance under mode-mismatch conditions. The BI performance of the presented pitch/roll gyroscope is comparable to that of the highest-performing mechanically trimmed piezo-MEMS yaw gyroscopes known to date, while offering the unique advantage of lower cost, better mode-matching resolution, and the flexibility of real-time frequency control.

本文提出了一种新型压电-MEMS俯仰/滚动陀螺仪,它将压电效应和静电效应结合在一起,首次实现了压电陀螺仪的静电模式匹配操作。平面外(OOP)模式(n = 3)和平面内(IP)模式(n = 2)的运动是正交的,这确保了 OOP 振幅不会受到设置在 IP 模式节点上的平行板的明显限制。因此,通过压电驱动的大 OOP 驱动振幅和通过静电微调的 IP 感测模式中的频率调谐可以同时实现,而且拉入风险较低,因此可以在调谐范围和线性驱动范围之间进行权衡。在 66 V 的调谐电压下,分频从 171 Hz 降至 0.1 Hz,灵敏度提高了 167 倍。模式匹配陀螺仪在定制真空室中的测试板上显示出 0.41°/√h 的角度随机漫步 (ARW) 和 8.85°/h 的偏置不稳定性 (BI),与模式不匹配条件下的性能相比,分别提高了 68 倍和 301 倍。所展示的俯仰/滚动陀螺仪的偏置不稳定性能可与迄今已知性能最高的机械微调压电-MEMS 偏航陀螺仪相媲美,同时还具有成本更低、模式匹配分辨率更高以及实时频率控制灵活性更强的独特优势。
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引用次数: 0
MRI and CT compatible asymmetric bilayer hydrogel electrodes for EEG-based brain activity monitoring. 与核磁共振成像和 CT 兼容的非对称双层水凝胶电极,用于基于脑电图的大脑活动监测。
IF 7.3 1区 工程技术 Q1 INSTRUMENTS & INSTRUMENTATION Pub Date : 2024-10-29 DOI: 10.1038/s41378-024-00805-2
Guoqiang Ren, Mingxuan Zhang, Liping Zhuang, Lianhui Li, Shunying Zhao, Jinxiu Guo, Yinchao Zhao, Zhaoxiang Peng, Jiangfan Lian, Botao Liu, Jingyun Ma, Xiaodong Hu, Zhewei Zhang, Ting Zhang, Qifeng Lu, Mingming Hao

The exploration of multi-dimensional brain activity with high temporal and spatial resolution is of great significance in the diagnosis of neurological disease and the study of brain science. Although the integration of electroencephalogram (EEG) with magnetic resonance imaging (MRI) and computed tomography (CT) provides a potential solution to achieve a brain-functional image with high spatiotemporal resolution, the critical issues of interface stability and magnetic compatibility remain challenging. Therefore, in this research, we proposed a conductive hydrogel EEG electrode with an asymmetrical bilayer structure, which shows the potential to overcome the challenges. Benefiting from the bilayer structure with different moduli, the hydrogel electrode exhibits high biological and mechanical compatibility with the heterogeneous brain-electrode interface. As a result, the impedance can be reduced compared with conventional metal electrodes. In addition, the hydrogel-based ionic conductive electrodes, which are free from metal conductors, are compatible with MRI and CT. Therefore, they can obtain high spatiotemporal resolution multi-dimensional brain information in clinical settings. The research outcome provides a new approach for establishing a platform for early diagnosis of brain diseases and the study of brain science.

探索具有高时空分辨率的多维大脑活动对神经疾病诊断和脑科学研究具有重要意义。虽然脑电图(EEG)与磁共振成像(MRI)和计算机断层扫描(CT)的整合为实现高时空分辨率的脑功能图像提供了一种潜在的解决方案,但界面稳定性和磁兼容性等关键问题仍然具有挑战性。因此,在这项研究中,我们提出了一种具有非对称双层结构的导电水凝胶脑电图电极,它显示出克服这些挑战的潜力。得益于具有不同模量的双层结构,该水凝胶电极与异质脑电极界面具有很高的生物和机械兼容性。因此,与传统金属电极相比,阻抗可以降低。此外,不含金属导体的水凝胶离子导电电极与核磁共振成像和 CT 兼容。因此,它们可以在临床环境中获得高时空分辨率的多维脑信息。该研究成果为建立脑疾病早期诊断和脑科学研究平台提供了一种新方法。
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