Cullen's sign of pancreatitis is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus. The sign takes 24–48 hours to appear and can predict increased mortality. In more severe cases, it may be accompanied by Grey Turner's sign (bruising of the flank) indicative of pancreatic necrosis with retroperitoneal or intraabdominal bleeding. Our case have an interesting presentation from which we can learn a new sign.
{"title":"Brown Semen: Think of Necrotizing Pancreatitis!","authors":"M. Walid","doi":"10.31579/2578-8965/010","DOIUrl":"https://doi.org/10.31579/2578-8965/010","url":null,"abstract":"Cullen's sign of pancreatitis is superficial edema and bruising in the subcutaneous fatty tissue around the umbilicus. The sign takes 24–48 hours to appear and can predict increased mortality. In more severe cases, it may be accompanied by Grey Turner's sign (bruising of the flank) indicative of pancreatic necrosis with retroperitoneal or intraabdominal bleeding. Our case have an interesting presentation from which we can learn a new sign.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85478465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: To determine if there is any observable effect of pre implantation genetic diagnosis (PGD) on obstetrical outcome and perinatal morbidity and mortality, birth defects, neonatal outcome in addition, finding the rate of misdiagnosis. Setting: King Faisal Specialist Hospital and Research Center (Reproductive Medicine & Perinatology Sections) at Riyadh, Saudi Arabia. Design: A retrospective chart review of PGD patients from Jan 2001- Dec 2009. Materials and Methods: A total of 70 PGD pregnancies and 70 matching spontaneously conceived pregnancies were reviewed. The main outcome measures were rate of multiple pregnancies, gestational age (GA) at delivery, mode of delivery, sex, apgar score (A/S), birth weight, presence of birth defects, misdiagnosis and perinatal and neonatal mortalities. Results: Data were collected from 79 children born after PGD and compared to 72 children born after spontaneous pregnancies. PGD group had significantly more multiple pregnancies. However, there was no statistically significant difference between other outcomes in terms of: birth weight, GA at delivery, sex distribution, perinatal mortality and presence of congenital malformations. The misdiagnosis rate was 1.4%. Conclusion: PGD does not add risk factors to the health of babies born after the procedure. The perinatal death rate and rate of congenital malformations were not higher for PGD group in this study.
{"title":"Obstetrical and Neonatal Outcome after Pre Implantation Genetic Diagnosis; Eight Year Experience at King Faisal Specialized Hospital & Research Center","authors":"A. Chamsi","doi":"10.31579/2578-8965/015","DOIUrl":"https://doi.org/10.31579/2578-8965/015","url":null,"abstract":"Objectives: To determine if there is any observable effect of pre implantation genetic diagnosis (PGD) on obstetrical outcome and perinatal morbidity and mortality, birth defects, neonatal outcome in addition, finding the rate of misdiagnosis. Setting: King Faisal Specialist Hospital and Research Center (Reproductive Medicine & Perinatology Sections) at Riyadh, Saudi Arabia. Design: A retrospective chart review of PGD patients from Jan 2001- Dec 2009. Materials and Methods: A total of 70 PGD pregnancies and 70 matching spontaneously conceived pregnancies were reviewed. The main outcome measures were rate of multiple pregnancies, gestational age (GA) at delivery, mode of delivery, sex, apgar score (A/S), birth weight, presence of birth defects, misdiagnosis and perinatal and neonatal mortalities. Results: Data were collected from 79 children born after PGD and compared to 72 children born after spontaneous pregnancies. PGD group had significantly more multiple pregnancies. However, there was no statistically significant difference between other outcomes in terms of: birth weight, GA at delivery, sex distribution, perinatal mortality and presence of congenital malformations. The misdiagnosis rate was 1.4%. Conclusion: PGD does not add risk factors to the health of babies born after the procedure. The perinatal death rate and rate of congenital malformations were not higher for PGD group in this study.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72875426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Ibrahim Taema, Rania Ali Ammar Abd El Hakim
Back ground: PET a disease of theories of unknown particular cause characterized by hypertensive disorder, protein excretion in urine that additionally could be accompanied or not by organ dysfunction. CA125 is an antigen measured by radioimmunoassay. Its physiological and molecular significance in obstetric diseases is not fully clarified most research trials are made on this antigen in obstetric research field to explore and investigate its role as a marker in various diseases. Aim: The current research was performed to evaluate and correlate the correlation between CA125 serum level in normal gestations and gestations affected by PET. Methodology: The current research study is composed of 300 singleton gestations. The study subjects were divided into 3 research groups: control research group (n = 100), mild PET research group (n = 100) and severe PET research group (n = 100). The three research groups were statistically alike as regards variables such as maternal age, gestational age and BMI.The research study was conducted at a private hospital in Jeddah, KSA, United Doctors Hospital. over 3 years from April 2014 to April 2017. Results: The current research study results displayed that no statistical significant difference existed between the research study groups concerning age, BMI, parity, smoking, GA and serum creatinine. On the other hand SBP, DBP, serum urea, serum CA125, urine protein, and NICU admission were statistically significantly lowest in control research group followed by mild PET research group and statistically significantly highest in severe PET research group. Interestingly it has been revealed in the current research findings that platelets count was statistically significantly lowest in severe PET research group with no statistically significant difference between control and mild groups. The current research study have evaluated in addition diagnostic performance of laboratory investigations performed between research study groups displayed the following Serum BUN, serum CA125 and proteinuria had statistically significant high diagnostic performance and features in discriminating between PET from normal (highest in urine protein).On the other hand Serum BUN had statistically significant moderate diagnostic performance and features , whereas serum CA125 and urine protein had statistically significant high diagnostic performance and features in discriminating severe from mild PET (highest in urine protein). Conclusion: Our research group came to the conclusion that serum CA125 level in maternal serum is directly correlated to PET presence and its degree of severity i.e CA-125 is a Biological marker mirroring the disease severity .Additionally it has the privilege of being. More readily available and considered less costly in comparison to other biological markers, It could be used as a screening tool for PET. However larger sample size should be considered in future research studies and consideration should be made for et
{"title":"CA125 serum levels in Correlation with Preeclampsia severity","authors":"Mohamed Ibrahim Taema, Rania Ali Ammar Abd El Hakim","doi":"10.31579/2578-8965/012","DOIUrl":"https://doi.org/10.31579/2578-8965/012","url":null,"abstract":"Back ground: PET a disease of theories of unknown particular cause characterized by hypertensive disorder, protein excretion in urine that additionally could be accompanied or not by organ dysfunction. CA125 is an antigen measured by radioimmunoassay. Its physiological and molecular significance in obstetric diseases is not fully clarified most research trials are made on this antigen in obstetric research field to explore and investigate its role as a marker in various diseases. Aim: The current research was performed to evaluate and correlate the correlation between CA125 serum level in normal gestations and gestations affected by PET. Methodology: The current research study is composed of 300 singleton gestations. The study subjects were divided into 3 research groups: control research group (n = 100), mild PET research group (n = 100) and severe PET research group (n = 100). The three research groups were statistically alike as regards variables such as maternal age, gestational age and BMI.The research study was conducted at a private hospital in Jeddah, KSA, United Doctors Hospital. over 3 years from April 2014 to April 2017. Results: The current research study results displayed that no statistical significant difference existed between the research study groups concerning age, BMI, parity, smoking, GA and serum creatinine. On the other hand SBP, DBP, serum urea, serum CA125, urine protein, and NICU admission were statistically significantly lowest in control research group followed by mild PET research group and statistically significantly highest in severe PET research group. Interestingly it has been revealed in the current research findings that platelets count was statistically significantly lowest in severe PET research group with no statistically significant difference between control and mild groups. The current research study have evaluated in addition diagnostic performance of laboratory investigations performed between research study groups displayed the following Serum BUN, serum CA125 and proteinuria had statistically significant high diagnostic performance and features in discriminating between PET from normal (highest in urine protein).On the other hand Serum BUN had statistically significant moderate diagnostic performance and features , whereas serum CA125 and urine protein had statistically significant high diagnostic performance and features in discriminating severe from mild PET (highest in urine protein). Conclusion: Our research group came to the conclusion that serum CA125 level in maternal serum is directly correlated to PET presence and its degree of severity i.e CA-125 is a Biological marker mirroring the disease severity .Additionally it has the privilege of being. More readily available and considered less costly in comparison to other biological markers, It could be used as a screening tool for PET. However larger sample size should be considered in future research studies and consideration should be made for et","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80473451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abd El-Naser Abd El-Gaber Ali, Khaled M Abdallah, A. Abdelhamid
Background: Prevention of the premature birth occurrence remains is considered one of the most tough challenges for obstetricians worldwide, mainly to avoid neonatal prematurity complications leading to short and long term morbidities additionally prematurity prevention will reduce premature neonatal mortality rates which is considered a major health concern of obstetricians, neonatologists and families. Objective: To compare and contrast the efficacy of Sildenafil citrate, Nifedipine and Dydrogesrone in prevention of premature labor in gestations with short cervix. Setting: Obstetrics & Gynecology Departments, Faculties of medicine, south Valley and Al-Azhar (Asyut) Universities, Egypt. Duration: from September 2014 to March 2018. Patients And Methds: the study was conducted on 300 pregnant women who randomly divided into three groups: Group I included 100 cases received Sildenafil citrate (Respatio tablet 20mg twice daily orally), Group II included 100 cases received Nifedipine (Epilat retard tablets 20mg twice daily orally) and Group III included 100 pregnant women received dydrogesreone 10 mg (Duphaston) twice daily orally. Results: incidence of preterm labor was (9.37, 8.51 and 14.28) in (Group I, Group II and Group II) respectively. Mean ± SD of cervical length at 32 weeks of gestation was mildly statistically significant among groups (p value <0.05) but no significance in neonatal outcome (p value >0.05) except birth weight which had a highly statistically significant difference (p value < 0.001). There was a highly statistically significant difference among studied groups as regard to drug side effects in (p value <0.001). Conclusion: Sildenafil citrate was as effective as Nifedipine and better than oral Dydrogesterone on myometrial relaxation and prevention of preterm birth in pregnant women who had short cervix.
{"title":"Sildenafil Citrate Versus Nifedipine and Dydrogesreone in Prevention of Preterm Labor with Short Cervix","authors":"Abd El-Naser Abd El-Gaber Ali, Khaled M Abdallah, A. Abdelhamid","doi":"10.31579/2578-8965/009","DOIUrl":"https://doi.org/10.31579/2578-8965/009","url":null,"abstract":"Background: Prevention of the premature birth occurrence remains is considered one of the most tough challenges for obstetricians worldwide, mainly to avoid neonatal prematurity complications leading to short and long term morbidities additionally prematurity prevention will reduce premature neonatal mortality rates which is considered a major health concern of obstetricians, neonatologists and families. Objective: To compare and contrast the efficacy of Sildenafil citrate, Nifedipine and Dydrogesrone in prevention of premature labor in gestations with short cervix. Setting: Obstetrics & Gynecology Departments, Faculties of medicine, south Valley and Al-Azhar (Asyut) Universities, Egypt. Duration: from September 2014 to March 2018. Patients And Methds: the study was conducted on 300 pregnant women who randomly divided into three groups: Group I included 100 cases received Sildenafil citrate (Respatio tablet 20mg twice daily orally), Group II included 100 cases received Nifedipine (Epilat retard tablets 20mg twice daily orally) and Group III included 100 pregnant women received dydrogesreone 10 mg (Duphaston) twice daily orally. Results: incidence of preterm labor was (9.37, 8.51 and 14.28) in (Group I, Group II and Group II) respectively. Mean ± SD of cervical length at 32 weeks of gestation was mildly statistically significant among groups (p value <0.05) but no significance in neonatal outcome (p value >0.05) except birth weight which had a highly statistically significant difference (p value < 0.001). There was a highly statistically significant difference among studied groups as regard to drug side effects in (p value <0.001). Conclusion: Sildenafil citrate was as effective as Nifedipine and better than oral Dydrogesterone on myometrial relaxation and prevention of preterm birth in pregnant women who had short cervix.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79506890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. El Helali, Amal el Shabrawi El Sayed, Wesal Hamdi Ali Hassan
Background: Sonographic fetal weight estimation is an important component of antenatal care. It was found to be more reliable method to establish fetal weight at term and more consistent in various period of gestations. Aim of study: to compare clinical and sonographic methods for assessment of fetal weight regarding sensitivity, specificity and accuracy. Subjects and Methods: The study recruited 100 women scheduled for delivery from ante-natal care clinic with 38 weeks or more of gestation. Fetal weight was assed clinically and by ultrasound. Both techniques were compared and analyzed. Results: Ultrasound assessment of fetal weight showed better performance than the clinical method regarding absolute errors and error percentages. Ultrasound assessment showed better sensitivity and specificity in detecting fetal weight > 3500 gm. Moreover, it showed less bias on Bland–Altman plot analysis. Conclusions: Ultrasound assessment of fetal weight is safe, reliable and sensitive method of fetal weight estimation.
{"title":"Sonographic Versus Clinical Fetal Weight Estimation Accuracy","authors":"A. El Helali, Amal el Shabrawi El Sayed, Wesal Hamdi Ali Hassan","doi":"10.31579/2578-8965/008","DOIUrl":"https://doi.org/10.31579/2578-8965/008","url":null,"abstract":"Background: Sonographic fetal weight estimation is an important component of antenatal care. It was found to be more reliable method to establish fetal weight at term and more consistent in various period of gestations. Aim of study: to compare clinical and sonographic methods for assessment of fetal weight regarding sensitivity, specificity and accuracy. Subjects and Methods: The study recruited 100 women scheduled for delivery from ante-natal care clinic with 38 weeks or more of gestation. Fetal weight was assed clinically and by ultrasound. Both techniques were compared and analyzed. Results: Ultrasound assessment of fetal weight showed better performance than the clinical method regarding absolute errors and error percentages. Ultrasound assessment showed better sensitivity and specificity in detecting fetal weight > 3500 gm. Moreover, it showed less bias on Bland–Altman plot analysis. Conclusions: Ultrasound assessment of fetal weight is safe, reliable and sensitive method of fetal weight estimation.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79166323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Rovira Pampalona, Daniel Vega Moreno, M. Degollada Bastos, Àngel Guerra Garcia, Joan Carles Mateu Pruñonosa, P. Bresco Torras
Introduction: The outpatient hysteroscopy is a minimally invasive technique, well tolerated by the majority of patients. However, the pain appears in a considerable percentage of patients, and this is the leading cause of failure. There are different factors related to pain. The aim of the present study is analyzing the association between emotional status and pain perception during the outpatient hysteroscopy. Material and methods: A retrospective survey. It was composed of 192 patients with sonographic diagnosis of endometrial polyp. An outpatient hysteroscopy was conducted from March 2013 to January 2015. Socio-demographic data and obstetrician history were collected. The intensity of pain during the test was evaluated by means of EVA, as well as the emotional state by means of Hospital Anxiety and Depression Scale (HADS). Results: The average score in VAS was 5.06. Regarding the score in HAD, it was 6.87 in anxiety and 4.25 in depression. For the entire sample, a positive correlation was evidenced between the intensity of pain (VAS) and the level of depressive symptomatology (HAD depression; p=0.001). This correlation was not shown in patients with anxiety symptomatology (p>0.05). The patients who did not succeed during the procedure, a correlation with the pain perception was observed, with a higher punctuation in VAS and depression scale (p<0.05). Conclusion: There are some factors such as the emotional status of the patient which could modulate the perception of the pain, showing a positive correlation between them. This is an important issue to considerer for the success of the ambulatory hysteroscopy.
{"title":"Influence Of Emotional Status On The Pain During The Outpatient Hysteroscopy","authors":"Jennifer Rovira Pampalona, Daniel Vega Moreno, M. Degollada Bastos, Àngel Guerra Garcia, Joan Carles Mateu Pruñonosa, P. Bresco Torras","doi":"10.31579/2578-8965/007","DOIUrl":"https://doi.org/10.31579/2578-8965/007","url":null,"abstract":"Introduction: The outpatient hysteroscopy is a minimally invasive technique, well tolerated by the majority of patients. However, the pain appears in a considerable percentage of patients, and this is the leading cause of failure. There are different factors related to pain. The aim of the present study is analyzing the association between emotional status and pain perception during the outpatient hysteroscopy. Material and methods: A retrospective survey. It was composed of 192 patients with sonographic diagnosis of endometrial polyp. An outpatient hysteroscopy was conducted from March 2013 to January 2015. Socio-demographic data and obstetrician history were collected. The intensity of pain during the test was evaluated by means of EVA, as well as the emotional state by means of Hospital Anxiety and Depression Scale (HADS). Results: The average score in VAS was 5.06. Regarding the score in HAD, it was 6.87 in anxiety and 4.25 in depression. For the entire sample, a positive correlation was evidenced between the intensity of pain (VAS) and the level of depressive symptomatology (HAD depression; p=0.001). This correlation was not shown in patients with anxiety symptomatology (p>0.05). The patients who did not succeed during the procedure, a correlation with the pain perception was observed, with a higher punctuation in VAS and depression scale (p<0.05). Conclusion: There are some factors such as the emotional status of the patient which could modulate the perception of the pain, showing a positive correlation between them. This is an important issue to considerer for the success of the ambulatory hysteroscopy.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87589377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective of research: To reveal and asses probable change in fetal cardiac physiological function of pregestational diabetic gestations. Research design: We performed a prospective research study of 31 gestations between 22 weeks’ gestational age and full term, and who had pregestational diabetes. All diabetic women recruited in the research performed had glycosylated hemoglobin lower than 6.5%. All gestations involved in the research performed had an early sonographic confirmation of fetal gestational age. Doppler study of blood flow via the fetal mitral and tricuspid valves were performed every 4 weeks using a pulsed wave sonographic Doppler machine with a 3.5- or 5-MHz ultrasound transducer. The subsequent parameters were analysed and calculated automatically from the revealed flow velocity waveforms: the peak velocity during the rapid ventricular filling phase (E wave) and during the atrial systole phase (A wave), and the ratio between these obtained velocities (E/A ratio); and the velocity time fundamental of the fetal atrioventricular blood flow (correlated with volume flow). A comparative statistical analysis between the Doppler parameters revealed from fetal examination of diabetic gestations and of normal gestations was performed by using the Mann-Whitney test. Results: Each gestation recruited for the study performed around four to five fetal echocardiographic Sonographic assessments at 22, 26, 30, 34, and 38 weeks’ gestation. The E/A ratio of the mitral and tricuspid valves did not Rise in fetuses of diabetic women during the third trimester and was observed to be statistically significantly higher manner in fetuses of nondiabetic gestations in comparison with fetuses of diabetic gestations at 34 and 38 gestational weeks. Calculated velocity time basic of the mitral and tricuspid valves when multiplied by fetal heart rate was greater, but not statistically significant, in fetuses of nondiabetic gestations when put in comparison with diabetic gestations fetuses at 34 and 38 weeks’ gestational weeks. The E-wave of both the mitral and tricuspid valves rised in both study categories all the way through pregnancy. The A-wave of the mitral and tricuspid valves rised only in diabetic gestation fetuses all over the final gestational trimester and was statistically significant in a greater manner at 34 and 38 gestational weeks compared with fetuses of nondiabetic women. Conclusion: variability in fetal atrioventricular blood flow forms between fetuses of diabetic gestations and normal gestations does not essentially cause variability in fetal functional cardiac compliance.
{"title":"Fetal cardiac functional performance and development of diabetic gestations","authors":"Sally Ahmed Refaat Kotb, A. Shaaban","doi":"10.31579/2578-8965/002","DOIUrl":"https://doi.org/10.31579/2578-8965/002","url":null,"abstract":"Objective of research: To reveal and asses probable change in fetal cardiac physiological function of pregestational diabetic gestations. Research design: We performed a prospective research study of 31 gestations between 22 weeks’ gestational age and full term, and who had pregestational diabetes. All diabetic women recruited in the research performed had glycosylated hemoglobin lower than 6.5%. All gestations involved in the research performed had an early sonographic confirmation of fetal gestational age. Doppler study of blood flow via the fetal mitral and tricuspid valves were performed every 4 weeks using a pulsed wave sonographic Doppler machine with a 3.5- or 5-MHz ultrasound transducer. The subsequent parameters were analysed and calculated automatically from the revealed flow velocity waveforms: the peak velocity during the rapid ventricular filling phase (E wave) and during the atrial systole phase (A wave), and the ratio between these obtained velocities (E/A ratio); and the velocity time fundamental of the fetal atrioventricular blood flow (correlated with volume flow). A comparative statistical analysis between the Doppler parameters revealed from fetal examination of diabetic gestations and of normal gestations was performed by using the Mann-Whitney test. Results: Each gestation recruited for the study performed around four to five fetal echocardiographic Sonographic assessments at 22, 26, 30, 34, and 38 weeks’ gestation. The E/A ratio of the mitral and tricuspid valves did not Rise in fetuses of diabetic women during the third trimester and was observed to be statistically significantly higher manner in fetuses of nondiabetic gestations in comparison with fetuses of diabetic gestations at 34 and 38 gestational weeks. Calculated velocity time basic of the mitral and tricuspid valves when multiplied by fetal heart rate was greater, but not statistically significant, in fetuses of nondiabetic gestations when put in comparison with diabetic gestations fetuses at 34 and 38 weeks’ gestational weeks. The E-wave of both the mitral and tricuspid valves rised in both study categories all the way through pregnancy. The A-wave of the mitral and tricuspid valves rised only in diabetic gestation fetuses all over the final gestational trimester and was statistically significant in a greater manner at 34 and 38 gestational weeks compared with fetuses of nondiabetic women. Conclusion: variability in fetal atrioventricular blood flow forms between fetuses of diabetic gestations and normal gestations does not essentially cause variability in fetal functional cardiac compliance.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90539990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: A retrospective research study revealing clinical features and prognostic parameters of 22 cases of gestational atypical hemolytic uremic syndrome. Methodology: A retrospective research study in an analytical manner of 22 cases of gestational Atypical hemolytic uremic syndrome from the Demerdash Maternity Hospital records using diverse management protocols. Results: 12 cases underwent plasma exchange management protocol with a favourable impact regarding renal response in only 8 cases. On the contrary, 10 cases were managed with high dose plasma infusion with an excellent renal response in 7 cases by regaining renal functional capacity in managed cases. Conclusion: The research performed by our group revealed considerable effectiveness of high dose therapy plasma infusion management of atypical HUS. Although therapeutic plasma exchange is the recommended treatment of HUS, this cumbersome procedure may not be available for all patients in an emergency. In this context, plasma infusion may represent an alternative first-line therapy.
{"title":"Retrospective Research exploring gestational atypical hemolytic uremic syndrome","authors":"A. Mansour, Mostafa Abd Elnasier Abd Elgawad","doi":"10.31579/2578-8965/004","DOIUrl":"https://doi.org/10.31579/2578-8965/004","url":null,"abstract":"Aim: A retrospective research study revealing clinical features and prognostic parameters of 22 cases of gestational atypical hemolytic uremic syndrome. Methodology: A retrospective research study in an analytical manner of 22 cases of gestational Atypical hemolytic uremic syndrome from the Demerdash Maternity Hospital records using diverse management protocols. Results: 12 cases underwent plasma exchange management protocol with a favourable impact regarding renal response in only 8 cases. On the contrary, 10 cases were managed with high dose plasma infusion with an excellent renal response in 7 cases by regaining renal functional capacity in managed cases. Conclusion: The research performed by our group revealed considerable effectiveness of high dose therapy plasma infusion management of atypical HUS. Although therapeutic plasma exchange is the recommended treatment of HUS, this cumbersome procedure may not be available for all patients in an emergency. In this context, plasma infusion may represent an alternative first-line therapy.","PeriodicalId":19413,"journal":{"name":"Obstetrics Gynecology and Reproductive Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73377378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Radwan, Mohamed Amr Hussein Elnoury, Sherif Fathi ElMekkawi
Objective: Acupuncture is frequently utilized to manage climacteric symptoms and other gynecological conditions. Laser acupuncture has the advantages of being noninvasive, reproducible, and convenient. This study sought to explore the effectiveness of laser acupoint stimulation in relieving symptoms associated with menopause. Methods: A randomized, double-blind, controlled study was conducted on 120 women diagnosed as menopausal patients (>1 year past last menstruation), aged 40 - 60 years with a Kupperman Menopause Index (KMI) equal or more than 15. women were randomized into Group A: Laser acupuncture (n=30), Group B: (HRT); Tibolone 2,5 mg/day (n=30) orally, Group C: Laser acupuncture and Tibolone 2,5 mg/day orally (n=30), Group D: Non interventional (self-care group) (n=30). Each patient was given a standard daily log and was required to record the frequency and severity of hot flashes and side effects of the treatment felt daily. The serum levels of follicle stimulating hormone (FSH), LH and E2 were detected before and after the treatment. Results: 120 women with postmenopausal symptoms were divided randomly into four equal groups; After the treatment and the follow-up, in (Group A) there was no significant difference regarding FSH, LH and E2 level before treatment and after treatment with LASER acupuncture, as regard (Group B); there was statistically significant difference before and after treatment concerning hot flashes of KMI and he levels of FSH, LH decreased significantly and the level of E2 increased significantly. Combined treatment using hormonal replacement therapy with Laser Acupoints (Group C) showed dramatic improvement in study subjects and the improvement was more than that in group B. There were no significant differences were found regarding self-care group on either frequency of hot flashes, FSH, LH and E2 level. Conclusions: Laser acupoints are effective and can be used as an alternative treatment to decrease the frequency and severity of postmenopausal hot flashes and postmenopausal symptoms especially if combined with Tibolone.
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