Pub Date : 2022-05-20DOI: 10.5812/numonthly-123517
T. Nguyen Van, Linh Phan Ha, Diep Pham Thao, Minh Nguyen Thi Binh, Minh Hoang Thi, Thuan Huynh Quang, L. Dam
Background: Chronic kidney disease (CKD) is an increasingly common disease worldwide and has become a global health problem, especially in Vietnam. Cystatin C is a marker for the detection, classification, and prognosis of CKD. Cystatin C is filtered entirely through the glomerular membrane, reabsorbed, and metabolized completely in the renal tubules. In case of damage to the kidneys, glomerular filtration rate declines, and some substances increase in the blood, such as cystatin C. The concentration of cystatin C changes with damage to the renal system. Objectives: This study aimed to estimate the concentration of cystatin C and its variation in the different stages of CKD. Methods: A descriptive, cross-sectional study was conducted on 40 healthy individuals and 137 patients with CKD grade III, IV, and V in 103 Hospital. The concentration of cystatin C was estimated in all subjects. Results: Cystatin C plasma levels were significantly higher in the CKD group (9.17 ± 3.75 mg/L) than in the control group (0.82 ± 0.12 mg/L). Cystatin C plasma levels increased linearly with the serious kidney failure as the stage of CKD. Conclusions: Cystatin C is an effective marker for estimating kidney damage in CKD.
{"title":"The Level of Plasma Cystatin C in Patients with Chronic Kidney Disease","authors":"T. Nguyen Van, Linh Phan Ha, Diep Pham Thao, Minh Nguyen Thi Binh, Minh Hoang Thi, Thuan Huynh Quang, L. Dam","doi":"10.5812/numonthly-123517","DOIUrl":"https://doi.org/10.5812/numonthly-123517","url":null,"abstract":"Background: Chronic kidney disease (CKD) is an increasingly common disease worldwide and has become a global health problem, especially in Vietnam. Cystatin C is a marker for the detection, classification, and prognosis of CKD. Cystatin C is filtered entirely through the glomerular membrane, reabsorbed, and metabolized completely in the renal tubules. In case of damage to the kidneys, glomerular filtration rate declines, and some substances increase in the blood, such as cystatin C. The concentration of cystatin C changes with damage to the renal system. Objectives: This study aimed to estimate the concentration of cystatin C and its variation in the different stages of CKD. Methods: A descriptive, cross-sectional study was conducted on 40 healthy individuals and 137 patients with CKD grade III, IV, and V in 103 Hospital. The concentration of cystatin C was estimated in all subjects. Results: Cystatin C plasma levels were significantly higher in the CKD group (9.17 ± 3.75 mg/L) than in the control group (0.82 ± 0.12 mg/L). Cystatin C plasma levels increased linearly with the serious kidney failure as the stage of CKD. Conclusions: Cystatin C is an effective marker for estimating kidney damage in CKD.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49623706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-13DOI: 10.5812/numonthly-121819
Tahereh Sabaghian, Minoo Heidari Almasi, Farzaneh Futuhi, M. Shabani, Azam Erfanifar, S. A. Ebadi
: Considering that there are different reports about the effects of angiotensin II type-I receptor blockers (ARB) and angiotensin-converting enzyme inhibitors (ACEI) on the outcomes of the patients with COVID-19, we aimed to conduct this retrospective study on 138 hypertensive patients (81 ACEI/ARB users) to assess the patients’ outcomes by comparing ACEI/ARB and non-ACEI/ARB users. Multivariate adjusted cox regression model, by considering the effect of other variables, demonstrated that increased age (HR = 1.04, 95% CI = 1.01 -1.07, P =0.003) and non- ACEI/ARB users (HR = 2.12 95% CI = 1.12 - 4.13, P = 0.021) were associated with increased risk of in-hospital mortality in about one week follow-up. In conclusion, we found that in-hospital mortality was lower in ACEI/ARB users, showing the positive effect of these treatments on patients’ outcomes.
考虑到血管紧张素II型受体阻滞剂(ARB)和血管紧张素转换酶抑制剂(ACEI)对COVID-19患者预后的影响有不同的报道，我们旨在对138例高血压患者(81例使用ACEI/ARB)进行回顾性研究，通过比较ACEI/ARB和非ACEI/ARB患者的预后。多因素校正cox回归模型在考虑其他变量影响的情况下显示，年龄增加(HR = 1.04, 95% CI = 1.01 ~ 1.07, P =0.003)和非ACEI/ARB使用者(HR = 2.12, 95% CI = 1.12 ~ 4.13, P = 0.021)与随访1周左右住院死亡风险增加相关。总之，我们发现ACEI/ARB使用者的住院死亡率较低，表明这些治疗对患者预后有积极影响。
{"title":"The Effect of ACEI/ARB on the Outcomes of COVID-19 Hospitalized Patients","authors":"Tahereh Sabaghian, Minoo Heidari Almasi, Farzaneh Futuhi, M. Shabani, Azam Erfanifar, S. A. Ebadi","doi":"10.5812/numonthly-121819","DOIUrl":"https://doi.org/10.5812/numonthly-121819","url":null,"abstract":": Considering that there are different reports about the effects of angiotensin II type-I receptor blockers (ARB) and angiotensin-converting enzyme inhibitors (ACEI) on the outcomes of the patients with COVID-19, we aimed to conduct this retrospective study on 138 hypertensive patients (81 ACEI/ARB users) to assess the patients’ outcomes by comparing ACEI/ARB and non-ACEI/ARB users. Multivariate adjusted cox regression model, by considering the effect of other variables, demonstrated that increased age (HR = 1.04, 95% CI = 1.01 -1.07, P =0.003) and non- ACEI/ARB users (HR = 2.12 95% CI = 1.12 - 4.13, P = 0.021) were associated with increased risk of in-hospital mortality in about one week follow-up. In conclusion, we found that in-hospital mortality was lower in ACEI/ARB users, showing the positive effect of these treatments on patients’ outcomes.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46972967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-11DOI: 10.5812/numonthly-122095
Elham Shahreki, A. Ansari-Moghaddam, R. Alavi Naini, Maryam Keikha, Ramin Bazi, A. Shahraki
Background: Following the global outbreak of severe acute respiratory syndrome coronavirus 2 in different communities, hemodialysis patients have not been spared by this viral infection. Objectives: This study evaluated the clinical symptoms laboratory and imaging findings in patients undergoing hemodialysis and compared these characteristics with the control group. Methods: The study was performed on 72 patients with positive COVID-19 polymerase chain reaction test, of whom 36 cases had end-stage renal disease undergoing hemodialysis and the remaining had no history of kidney diseases. After matching the two groups in terms of age, sex, and other underlying diseases, the clinical, laboratory, and chest computed tomography (CT) scan findings were compared between the case and control groups. Results: The mean age of dialysis patients was 42.52 ± 12.10 years and 48.58 ± 17.35 years in the control group. The study results revealed that hemodialysis patients had less fever, cough, and shortness of breath than the control group (P-value < 0.05). Hemoglobin, lymphocyte, and platelet counts were significantly lower in hemodialysis patients in comparison to the control group (P-value < 0.05). C-reactive protein was significantly higher in patients undergoing hemodialysis (P-value = 0.01), and ground-glass opacification was observed more in patients undergoing hemodialysis compared to controls, but this difference was not statically significant (P = 0.07). Conclusions: Hemodialysis patients had fewer initial clinical symptoms but more abnormalities in laboratory findings and ground-glass opacities on chest CT scans and a higher mortality rate.
{"title":"Clinical and Para-Clinical Findings of COVID19 in Hemodialysis Patients Compared to Control Group: A Case-Control Study","authors":"Elham Shahreki, A. Ansari-Moghaddam, R. Alavi Naini, Maryam Keikha, Ramin Bazi, A. Shahraki","doi":"10.5812/numonthly-122095","DOIUrl":"https://doi.org/10.5812/numonthly-122095","url":null,"abstract":"Background: Following the global outbreak of severe acute respiratory syndrome coronavirus 2 in different communities, hemodialysis patients have not been spared by this viral infection. Objectives: This study evaluated the clinical symptoms laboratory and imaging findings in patients undergoing hemodialysis and compared these characteristics with the control group. Methods: The study was performed on 72 patients with positive COVID-19 polymerase chain reaction test, of whom 36 cases had end-stage renal disease undergoing hemodialysis and the remaining had no history of kidney diseases. After matching the two groups in terms of age, sex, and other underlying diseases, the clinical, laboratory, and chest computed tomography (CT) scan findings were compared between the case and control groups. Results: The mean age of dialysis patients was 42.52 ± 12.10 years and 48.58 ± 17.35 years in the control group. The study results revealed that hemodialysis patients had less fever, cough, and shortness of breath than the control group (P-value < 0.05). Hemoglobin, lymphocyte, and platelet counts were significantly lower in hemodialysis patients in comparison to the control group (P-value < 0.05). C-reactive protein was significantly higher in patients undergoing hemodialysis (P-value = 0.01), and ground-glass opacification was observed more in patients undergoing hemodialysis compared to controls, but this difference was not statically significant (P = 0.07). Conclusions: Hemodialysis patients had fewer initial clinical symptoms but more abnormalities in laboratory findings and ground-glass opacities on chest CT scans and a higher mortality rate.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42992267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-11DOI: 10.5812/numonthly-121289
Kien Nguyen Trung, Hung Ta Viet, Hanh Nguyen Thi Hien, Van Nguyen Khanh, Tuyen Thai Danh, Thang Le Viet
Background: Iron management is essential for anemia treatment in chronic kidney disease. The reticulocyte hemoglobin equivalent (RET-He) is a reticulocyte parameter that reflects hemoglobin synthesis of newly formed erythrocytes in the bone marrow in real-time. Objectives: This study aims to evaluate the role of reticulocyte hemoglobin equivalent (RET-He) in predicting iron deficiency in chronic kidney disease (CKD) patients. Methods: Following a descriptive cross-sectional observational design, this study was conducted on 131 adult patients with CKD stages 3 - 5. Laboratory indices, including complete blood count, some biochemical indices, iron status, and reticulocyte indices (including RET-He), were measured. Iron deficiency (ID) was defined as TSAT < 20%, where serum ferritin level > 100 ng/mL was defined as functional ID, while serum ferritin level
{"title":"Evaluation of Predicting the Value of the Reticulocyte Hemoglobin Equivalent for Iron Deficiency in Chronic Kidney Disease Patients","authors":"Kien Nguyen Trung, Hung Ta Viet, Hanh Nguyen Thi Hien, Van Nguyen Khanh, Tuyen Thai Danh, Thang Le Viet","doi":"10.5812/numonthly-121289","DOIUrl":"https://doi.org/10.5812/numonthly-121289","url":null,"abstract":"Background: Iron management is essential for anemia treatment in chronic kidney disease. The reticulocyte hemoglobin equivalent (RET-He) is a reticulocyte parameter that reflects hemoglobin synthesis of newly formed erythrocytes in the bone marrow in real-time. Objectives: This study aims to evaluate the role of reticulocyte hemoglobin equivalent (RET-He) in predicting iron deficiency in chronic kidney disease (CKD) patients. Methods: Following a descriptive cross-sectional observational design, this study was conducted on 131 adult patients with CKD stages 3 - 5. Laboratory indices, including complete blood count, some biochemical indices, iron status, and reticulocyte indices (including RET-He), were measured. Iron deficiency (ID) was defined as TSAT < 20%, where serum ferritin level > 100 ng/mL was defined as functional ID, while serum ferritin level","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46645056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: End-stage kidney disease (ESKD) patients undergoing hemodialysis suffer from multiple comorbidities, including cardiovascular disorders. Calcium phosphate product is one of the stand-alone cardiovascular risk markers. The relationship between calcium phosphate product-based cardiovascular risk and HRQOL needs to be further studied. Methods: This project was a cross-sectional survey using the Kidney Disease Quality of Life (KDQOL-36) of patient health-related quality of life (HRQOL). Calcium phosphate product was calculated from the information in the medical records. The study was conducted at the hemodialysis ward of the hospital affiliated with the Thumbay University. Spearman’s correlation coefficient (rs) was used to explore an association (correlation) between HRQOL domains and categorized calcium phosphate products. In this study, the significance level was set at P = 0.05, and SPSS software version 26 was used to analyze the data. Results: The mean score (58%) of the Short Form (SF)-12 Physical composite was lower than the mean score of mental composite (70%). Among kidney-specific domains, the highest HRQOL score was associated with the symptom/problem list (71%), followed by effects on kidney disease (63%) and the burden of kidney disease (40%), respectively. There was a non-strong negative correlation between the ‘burden of kidney disease’ and corrected calcium phosphate product (rs -0.439, P-value 0.032) and between ‘symptom/ problem list’ and corrected calcium phosphate product (rs -0.431, P-value 0.035), and the other KDQOL domains revealed insignificant relationship with calcium phosphate product. Conclusions: ESKD affects HRQOL in patients undergoing maintenance hemodialysis. Calcium phosphate product also needs to be decreased by < 55 mg/dL in the concerned patients. Calcium phosphate product and HRQOL were not correlated in this group of patients. The HRQOL measures need to be revised to detect cardiovascular risk.
{"title":"On the Relationship Between Cardiovascular Risk Marker Calcium Phosphate Product and Health-Related Quality of Life in Hemodialysis Patients","authors":"Maryam Alrais, Dixon Thomas, Hoda Abdolmonem, Seeba Zachariah, Rajaram Jagdale, Danial E. Baker","doi":"10.5812/numonthly-121520","DOIUrl":"https://doi.org/10.5812/numonthly-121520","url":null,"abstract":"Background: End-stage kidney disease (ESKD) patients undergoing hemodialysis suffer from multiple comorbidities, including cardiovascular disorders. Calcium phosphate product is one of the stand-alone cardiovascular risk markers. The relationship between calcium phosphate product-based cardiovascular risk and HRQOL needs to be further studied. Methods: This project was a cross-sectional survey using the Kidney Disease Quality of Life (KDQOL-36) of patient health-related quality of life (HRQOL). Calcium phosphate product was calculated from the information in the medical records. The study was conducted at the hemodialysis ward of the hospital affiliated with the Thumbay University. Spearman’s correlation coefficient (rs) was used to explore an association (correlation) between HRQOL domains and categorized calcium phosphate products. In this study, the significance level was set at P = 0.05, and SPSS software version 26 was used to analyze the data. Results: The mean score (58%) of the Short Form (SF)-12 Physical composite was lower than the mean score of mental composite (70%). Among kidney-specific domains, the highest HRQOL score was associated with the symptom/problem list (71%), followed by effects on kidney disease (63%) and the burden of kidney disease (40%), respectively. There was a non-strong negative correlation between the ‘burden of kidney disease’ and corrected calcium phosphate product (rs -0.439, P-value 0.032) and between ‘symptom/ problem list’ and corrected calcium phosphate product (rs -0.431, P-value 0.035), and the other KDQOL domains revealed insignificant relationship with calcium phosphate product. Conclusions: ESKD affects HRQOL in patients undergoing maintenance hemodialysis. Calcium phosphate product also needs to be decreased by < 55 mg/dL in the concerned patients. Calcium phosphate product and HRQOL were not correlated in this group of patients. The HRQOL measures need to be revised to detect cardiovascular risk.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48281431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-19DOI: 10.5812/numonthly-119224
S. R. Yahyazadeh, S. Izadi, Seyed Hassan Inanloo
Background: To investigate the clinical significance of the intravesical prostatic protrusion (IPP) index in benign prostatic hyperplasia (BPH) patients to clarify its diagnostic value in predicting the clinical and structural abnormalities of the prostate. Methods: In this descriptive and analytical cross-sectional study, every man older than 50 years with lower urinary tract symptoms (LUTS), predominantly voiding or obstructive, suggestive of BPH were included. The patients were evaluated to determine the following indices: International Prostate Symptom Score (IPSS) index, quality of life (QoL), prostate volume (PV) and postvoid residual urine (PVR), serum PSA level, and the maximum urinary flow rate (Qmax) obtained by uroflowmetry. Subsequently, the assessment of the IPP index was conducted by transabdominal ultrasonography. The categorization of the IPP index was done into 3 grades: grade one (below 5 mm), grade two (between 5 and 10 mm), and grade three (greater than 10 mm). Results: A significant direct correlation between the IPP and IPSS, QoL, PV, PVR, and serum PSA, as well as inversely with the Qmax, was detected before and after medical treatment. Also, the need for surgical intervention increased significantly with the IPP index. Conclusions: The IPP can be used to evaluate and predict the severity of symptoms and outcomes in patients with clinical BPH.
{"title":"Clinical Significance of Intravesical Prostatic Protrusion Index in Patients with Clinical Diagnosis of Benign Prostatic Hyperplasia","authors":"S. R. Yahyazadeh, S. Izadi, Seyed Hassan Inanloo","doi":"10.5812/numonthly-119224","DOIUrl":"https://doi.org/10.5812/numonthly-119224","url":null,"abstract":"Background: To investigate the clinical significance of the intravesical prostatic protrusion (IPP) index in benign prostatic hyperplasia (BPH) patients to clarify its diagnostic value in predicting the clinical and structural abnormalities of the prostate. Methods: In this descriptive and analytical cross-sectional study, every man older than 50 years with lower urinary tract symptoms (LUTS), predominantly voiding or obstructive, suggestive of BPH were included. The patients were evaluated to determine the following indices: International Prostate Symptom Score (IPSS) index, quality of life (QoL), prostate volume (PV) and postvoid residual urine (PVR), serum PSA level, and the maximum urinary flow rate (Qmax) obtained by uroflowmetry. Subsequently, the assessment of the IPP index was conducted by transabdominal ultrasonography. The categorization of the IPP index was done into 3 grades: grade one (below 5 mm), grade two (between 5 and 10 mm), and grade three (greater than 10 mm). Results: A significant direct correlation between the IPP and IPSS, QoL, PV, PVR, and serum PSA, as well as inversely with the Qmax, was detected before and after medical treatment. Also, the need for surgical intervention increased significantly with the IPP index. Conclusions: The IPP can be used to evaluate and predict the severity of symptoms and outcomes in patients with clinical BPH.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47781135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-16DOI: 10.5812/numonthly.121459
Fatemeh Tanhaye Kalate Sabz, F. Amjadi, Z. Zandieh, M. Ashrafi
Context: The SARS-CoV-2 virus causes dysfunction of vital organs in the body. Concerns about the destructive effect of SARS-CoV-2 on human reproductive tissues and fertility have increased. Evaluation of the possible mechanisms by which SARS-CoV-2 causes infertility is essential for effective prevention and treatment. This review aims to assess the studies that have been conducted on SARS-CoV-2 impacts on the human reproductive system. Evidence Acquisition: This review study investigated articles indexed in PubMed, Science-Direct, Scopus, and google scholar databases from 2019 to 2021. The Keywords SARS-CoV-2, COVID-19, human reproductive system, testis, and ovary were searched in the mentioned databases. Results: The present study assessed the expression of SARS-CoV-2-specific receptors, the presence of the virus in the human reproductive system, and the mechanisms by which this virus can affect human fertility. Conclusions: SARS-CoV-2, like other viruses, may indirectly influence the male reproductive system through cytokine storms, inflammation-causing oxidative stress, and its possible complications. The direct effects of SARS-CoV-2 on the male reproductive system are also reported. The testis may be a potential target for the SARS-CoV-2 virus. The impact of the SARS-CoV-2 virus on women's reproductive performance is unknown and requires further investigation.
{"title":"SARS-CoV-2 and its Implications for the Human Reproductive System: A Review Article","authors":"Fatemeh Tanhaye Kalate Sabz, F. Amjadi, Z. Zandieh, M. Ashrafi","doi":"10.5812/numonthly.121459","DOIUrl":"https://doi.org/10.5812/numonthly.121459","url":null,"abstract":"Context: The SARS-CoV-2 virus causes dysfunction of vital organs in the body. Concerns about the destructive effect of SARS-CoV-2 on human reproductive tissues and fertility have increased. Evaluation of the possible mechanisms by which SARS-CoV-2 causes infertility is essential for effective prevention and treatment. This review aims to assess the studies that have been conducted on SARS-CoV-2 impacts on the human reproductive system. Evidence Acquisition: This review study investigated articles indexed in PubMed, Science-Direct, Scopus, and google scholar databases from 2019 to 2021. The Keywords SARS-CoV-2, COVID-19, human reproductive system, testis, and ovary were searched in the mentioned databases. Results: The present study assessed the expression of SARS-CoV-2-specific receptors, the presence of the virus in the human reproductive system, and the mechanisms by which this virus can affect human fertility. Conclusions: SARS-CoV-2, like other viruses, may indirectly influence the male reproductive system through cytokine storms, inflammation-causing oxidative stress, and its possible complications. The direct effects of SARS-CoV-2 on the male reproductive system are also reported. The testis may be a potential target for the SARS-CoV-2 virus. The impact of the SARS-CoV-2 virus on women's reproductive performance is unknown and requires further investigation.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46040822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-25DOI: 10.5812/numonthly.120605
Amin Mirsani, Sepideh Karkon Shayan, A. Sadeghian, Raheleh Baradaran
Introduction: Ureteral injuries are considered as rare complications of posterior lumbar interbody fusion (PLIF). There are few reports in the literature on ureteral injuries following PLIF. The present report presented a case of right ureteral injury by passing five years from PLIF. Case Presentation: The patient was a 51-year-old woman who has been referred to urologist with the complaints of flank pain, fever, anorexia, vomiting, and nausea, and a history of PLIF five years ago. After radiological examinations, ureteral obstruction was diagnosed and then open surgery was performed. Severe adhesions and fibrosis were observed in the retroperitoneal next to the lumbar vertebra implant. Thereafter, the ureteral stenosis was removed, the ureter was anastomosed end-to-end, and Double J was placed. The anastomosis site was covered with a flap of perinephric adipose tissue in order to prevent re-fibrosis. Conclusions: This report aimed to inform surgeons of a rare complication, a ureteral injury that has happened five years after PLIF, along with its non-specific signs.
{"title":"Ureteral Injury Following Posterior Lumbar Interbody Fusion After Five Years: A Rare Case","authors":"Amin Mirsani, Sepideh Karkon Shayan, A. Sadeghian, Raheleh Baradaran","doi":"10.5812/numonthly.120605","DOIUrl":"https://doi.org/10.5812/numonthly.120605","url":null,"abstract":"Introduction: Ureteral injuries are considered as rare complications of posterior lumbar interbody fusion (PLIF). There are few reports in the literature on ureteral injuries following PLIF. The present report presented a case of right ureteral injury by passing five years from PLIF. Case Presentation: The patient was a 51-year-old woman who has been referred to urologist with the complaints of flank pain, fever, anorexia, vomiting, and nausea, and a history of PLIF five years ago. After radiological examinations, ureteral obstruction was diagnosed and then open surgery was performed. Severe adhesions and fibrosis were observed in the retroperitoneal next to the lumbar vertebra implant. Thereafter, the ureteral stenosis was removed, the ureter was anastomosed end-to-end, and Double J was placed. The anastomosis site was covered with a flap of perinephric adipose tissue in order to prevent re-fibrosis. Conclusions: This report aimed to inform surgeons of a rare complication, a ureteral injury that has happened five years after PLIF, along with its non-specific signs.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45334836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-08DOI: 10.5812/numonthly.121625
A. Ghadian, M. Javanbakht, S. Mohammadi, M. Ebrahimi, Mahdi Ramezani-binabaj
Background: Prostate cancer is one of the leading causes of mortality in Iran and is the third most common cancer in male population. Objectives: The present study aimed to evaluate the necessity and efficacy of establishing a specific rehabilitation center for patients with prostate cancer. Methods: In this basic-applied research, we proposed the establishment of a rehabilitation center to support and decrease the complications of various treatments in patients with prostate cancer. After entering the rehabilitation process, a well-educated nurse and general physician trained in one of the similar European centers supported the patients to help themselves cope with unresolvable symptoms. To evaluate the patients’ satisfaction with the services offered by this rehabilitation center, the patients were asked to fill the Prostate Cancer-Related Quality of Life Questionnaire seven months after the first session. Results: In this study, 133 patients with prostate cancer (71 persons in the control group and 62 persons in the conservative treatment group) underwent the analysis. The participants’ mean age was 62.8 ± 2.31 years in the control group and 63.3 ± 4.54 years in the treatment group (P = 0.613). Moreover, the participants’ mean lifestyle scores were 5.3 ± 2.5 and 5.8 ± 2.8 in the control and treatment groups before the supportive care, respectively (P = 0.460). However, following the intervention, the scores were 5.3 ± 2.1 and 7.6 ± 1.9 in the control and treatment groups, respectively (P = 0.001). The mean lifestyle score was significantly higher after supportive care in the treatment group (P = 0.001). Conclusions: A prostate cancer-specified rehabilitation center providing supportive care by an educated healthcare professional can significantly improve the quality of life of patients with prostate cancer.
{"title":"Establishment of a Rehabilitation Center for Patients with Prostate Cancer","authors":"A. Ghadian, M. Javanbakht, S. Mohammadi, M. Ebrahimi, Mahdi Ramezani-binabaj","doi":"10.5812/numonthly.121625","DOIUrl":"https://doi.org/10.5812/numonthly.121625","url":null,"abstract":"Background: Prostate cancer is one of the leading causes of mortality in Iran and is the third most common cancer in male population. Objectives: The present study aimed to evaluate the necessity and efficacy of establishing a specific rehabilitation center for patients with prostate cancer. Methods: In this basic-applied research, we proposed the establishment of a rehabilitation center to support and decrease the complications of various treatments in patients with prostate cancer. After entering the rehabilitation process, a well-educated nurse and general physician trained in one of the similar European centers supported the patients to help themselves cope with unresolvable symptoms. To evaluate the patients’ satisfaction with the services offered by this rehabilitation center, the patients were asked to fill the Prostate Cancer-Related Quality of Life Questionnaire seven months after the first session. Results: In this study, 133 patients with prostate cancer (71 persons in the control group and 62 persons in the conservative treatment group) underwent the analysis. The participants’ mean age was 62.8 ± 2.31 years in the control group and 63.3 ± 4.54 years in the treatment group (P = 0.613). Moreover, the participants’ mean lifestyle scores were 5.3 ± 2.5 and 5.8 ± 2.8 in the control and treatment groups before the supportive care, respectively (P = 0.460). However, following the intervention, the scores were 5.3 ± 2.1 and 7.6 ± 1.9 in the control and treatment groups, respectively (P = 0.001). The mean lifestyle score was significantly higher after supportive care in the treatment group (P = 0.001). Conclusions: A prostate cancer-specified rehabilitation center providing supportive care by an educated healthcare professional can significantly improve the quality of life of patients with prostate cancer.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46827247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-26DOI: 10.5812/numonthly.121179
A. Hasan, G. Singh, S. Panda
Background: Renal stone disease is a very common disease, and its lifetime prevalence is 1 - 15%, with a gradual rise in incidence and disease prevalence. There are significant financial implications of its management. Nowadays, for big (typically > 2 cm) renal and upper ureteric stones, PCNL is widely regarded as the first-line treatment. Because most of the intrarenal collecting systems can be accessed by superior calyceal puncture in PCNL, good stone clearance can be achieved. The “Guy’s Stone Score” is a useful technique for categorizing the complexity of PCNL. Objectives: This study aimed to evaluate the role of Guys Stone Score based on KUB and intravenous urography to predict the success rate, grading, and complexity of PCNL, which are performed via the upper pole access. Methods: The present prospective, non-randomized observational study was undertaken in the Department of Urology and Renal transplantation, SCBMCH, Cuttack, from 1st November 2017 to 31st October 2019. A total of 104 patients were enrolled in the study in whom PCNL was performed through superior calyceal puncture, based on preoperative intravenous pyelogram. The Guy's Stone Score was calculated, and the complexity of the procedure was graded using radiological studies, then the outcome was determined accordingly. Results: In this study, 59.6% of the patients had immediate success among them 29.0% had grade 3, and 6.5% had grade 4 GSS. Moreover, 38.4% of the patients had clinically significant residual fragments among them, 75.0% had grade 4, and 20.0% had grade 3 GSS.23% of the patients underwent REDO-PCNL and 11.5% of the patients underwent necessary procedure of ESWL. Conclusions: The present study shows that an intravenous pyelogram-based Guy’s Stone Score (GSS) is an easy-to-use tool in predicting the early success rate and potential difficulties and complications in PCNL performed through superior calyceal puncture.
背景:肾结石是一种非常常见的疾病，其终生患病率为1 - 15%，发病率和患病率逐渐上升。它的管理涉及重大的财政问题。目前，对于大的(通常为bbb2cm)肾结石和输尿管上段结石，PCNL被广泛认为是一线治疗方法。由于大多数肾内收集系统可通过肾盏穿刺进入PCNL，因此可获得良好的结石清除。“Guy’s Stone Score”是一种对PCNL复杂性进行分类的有用技术。目的:本研究旨在评估基于KUB和静脉尿路造影的Guys Stone评分在预测PCNL成功率、分级和复杂性方面的作用，PCNL是通过上极通道进行的。方法:本前瞻性、非随机观察性研究于2017年11月1日至2019年10月31日在克塔克SCBMCH泌尿外科和肾移植科进行。研究共纳入104例患者，在术前静脉肾盂造影的基础上，通过上盏穿刺进行PCNL。计算Guy's Stone评分，并使用放射学研究对手术的复杂性进行分级，然后据此确定结果。结果:本研究中，59.6%的患者立即成功，其中29.0%为3级，6.5%为4级GSS。此外，38.4%的患者有临床意义的残留碎片，其中75.0%为4级，20.0%为3级gss, 23%的患者接受了REDO-PCNL, 11.5%的患者接受了必要的ESWL手术。结论:本研究显示静脉肾盂造影Guy’s Stone Score (GSS)是一种易于使用的工具，可预测通过上盏穿刺进行PCNL的早期成功率、潜在困难和并发症。
{"title":"Intravenous Pyelogram (IVP)-Based Guy’s Stone Score (GSS) Utility for Prediction of Outcomes of Upper Pole Access Percutaneous Nephrolithotomy (PCNL)","authors":"A. Hasan, G. Singh, S. Panda","doi":"10.5812/numonthly.121179","DOIUrl":"https://doi.org/10.5812/numonthly.121179","url":null,"abstract":"Background: Renal stone disease is a very common disease, and its lifetime prevalence is 1 - 15%, with a gradual rise in incidence and disease prevalence. There are significant financial implications of its management. Nowadays, for big (typically > 2 cm) renal and upper ureteric stones, PCNL is widely regarded as the first-line treatment. Because most of the intrarenal collecting systems can be accessed by superior calyceal puncture in PCNL, good stone clearance can be achieved. The “Guy’s Stone Score” is a useful technique for categorizing the complexity of PCNL. Objectives: This study aimed to evaluate the role of Guys Stone Score based on KUB and intravenous urography to predict the success rate, grading, and complexity of PCNL, which are performed via the upper pole access. Methods: The present prospective, non-randomized observational study was undertaken in the Department of Urology and Renal transplantation, SCBMCH, Cuttack, from 1st November 2017 to 31st October 2019. A total of 104 patients were enrolled in the study in whom PCNL was performed through superior calyceal puncture, based on preoperative intravenous pyelogram. The Guy's Stone Score was calculated, and the complexity of the procedure was graded using radiological studies, then the outcome was determined accordingly. Results: In this study, 59.6% of the patients had immediate success among them 29.0% had grade 3, and 6.5% had grade 4 GSS. Moreover, 38.4% of the patients had clinically significant residual fragments among them, 75.0% had grade 4, and 20.0% had grade 3 GSS.23% of the patients underwent REDO-PCNL and 11.5% of the patients underwent necessary procedure of ESWL. Conclusions: The present study shows that an intravenous pyelogram-based Guy’s Stone Score (GSS) is an easy-to-use tool in predicting the early success rate and potential difficulties and complications in PCNL performed through superior calyceal puncture.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43697907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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