Carbohydrate Polymers最新文献_第7页

Corrigendum to “A one-step approach to make cellulose-based hydrogels of various transparency and swelling degrees” [Carbohydrate Polymers, volume 186, 15 April 2018, pages 208–216] 一步法制作不同透明度和溶胀度的纤维素基水凝胶》[《碳水化合物聚合物》，第186卷，2018年4月15日，第208-216页]更正

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-22 DOI: 10.1016/j.carbpol.2024.122857

Hongjuan Geng

引用次数: 0

Glucose-activated self-cascade antibacterial and pro-angiogenesis nanozyme-functionalized chitosan-arginine thermosensitive hydrogel for chronic diabetic wounds healing 用于慢性糖尿病伤口愈合的葡萄糖激活型自级联抗菌和促血管生成纳米酶功能化壳聚糖-精氨酸热敏水凝胶

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-21 DOI: 10.1016/j.carbpol.2024.122894

Shuhui Chen, Jiali Chen, Xinlong Wang, Zhaofei Yang, Jinxi Lan, Liudi Wang, Bingjie Ji, Yue Yuan

Affected by persistent hyperglycemia, diabetic neuropathy, and vasculopathy hinder the progression of wound healing by exacerbating susceptibility to recurrent bacterial infection and impairing vascularization. In order to cater to the requirements of diabetic chronic wound healing at various stages, we designed an antibacterial and pro-angiogenic wound dressing with localized glucose-lowering capacity. In this study, we constructed a copper-based metal-organic framework (MOF) nanozyme and loaded with glucose oxidase (GOX) to prepare Cu-MOF/GOX, which was subsequently integrated with CS-Arg (chitosan modified by L-Arginine) and Pluronic (F127) to fabricate multifunctional Cu-MOF/GOX-Gel thermosensitive hydrogel. The GOX generated H₂O₂ (hydrogen peroxide) and gluconic acid by consuming high blood glucose at the wound site, thus initiating an efficient antibacterial self-cascade catalytic in the initial stages of wound healing. With the further catalysis of in situ generated H₂O₂, NO (nitric oxide) was gradually released from the hydrogel, facilitating angiogenesis and accumulation of collagen, thereby expediting subsequent phases of wound healing. Overall, the Cu-MOF/GOX-Gel exhibits a comprehensive ability to locally regulate blood glucose levels, while also synergistically promoting antibacterial activity and angiogenesis, that effectively chronic diabetic wounds healing.

受持续高血糖的影响，糖尿病神经病变和血管病变会加剧反复细菌感染的易感性并损害血管生成，从而阻碍伤口愈合的进展。为了满足糖尿病慢性伤口愈合不同阶段的要求，我们设计了一种具有局部降糖能力的抗菌和促进血管生成的伤口敷料。在这项研究中，我们构建了一种铜基金属有机框架（MOF）纳米酶，并负载葡萄糖氧化酶（GOX）以制备 Cu-MOF/GOX，随后将其与 CS-Arg（由 L-精氨酸修饰的壳聚糖）和 Pluronic（F127）结合，制备出多功能 Cu-MOF/GOX-Gel 热敏水凝胶。GOX 通过消耗伤口处的高血糖产生 H2O2（过氧化氢）和葡萄糖酸，从而在伤口愈合初期启动了高效的抗菌自级联催化。随着原位生成的 H2O2 的进一步催化，NO（一氧化氮）逐渐从水凝胶中释放出来，促进了血管生成和胶原蛋白的积累，从而加快了伤口愈合的后续阶段。总之，Cu-MOF/GOX-凝胶具有局部调节血糖水平的综合能力，同时还能协同促进抗菌活性和血管生成，从而有效地促进慢性糖尿病伤口的愈合。

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引用次数: 0

Supramolecular cyclodextrin-based reservoir as nasal delivery vehicle for rivastigmine to brain 基于超分子环糊精的储层作为利伐斯的明的鼻腔给药载体输送到大脑

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-21 DOI: 10.1016/j.carbpol.2024.122881

Manli Wang , Yuting Lv , Huipeng Xu , Xiangyu Zhao , Guoqing Zhang , Siwen Wang , Caifen Wang , Wenting Wu , Li Wu , Weifeng Zhu , Jiwen Zhang

The purpose of this study involved the synthesis of supramolecular reservoir (i.e. cyclodextrin metal-organic framework, MOF) using cyclodextrins as building blocks, followed by cross-linking to obtain crosslinked CD framework (CDF) using CD-MOF as template and functionalized with borneol (BO) to enhance rivastigmine (RIV) permeation and facilitate brain targeting via intranasal administration. Utilizing BO modified CDF (BO-CDF) with cubic shape as a carrier for the encapsulation of RIV, a nasal RIV delivery system (RIV@BO-CDF) was fabricated. The particle size of RIV@BO-CDF was approximately 250 nm, and the drug loading capacity reached 15 ± 2 %. BO-CDF improved the mucoadhesion and enhanced RIV permeability with the plasma concentration-time curve (AUC), the brain AUC and the peak drug concentration within brain in rats 1.7, 2.3 and 8 times than that of oral RIV solution, respectively. The relative drug targeting efficiency percentage (DTE, 139.4 %) and direct drug transfer percentage (DTP, 28.3 %) of RIV@BO-COF indicated good targeting efficiency and direct nose-to-brain drug delivery. Overall, this study provides a potential application of supramolecular cyclodextrin-based reservoir to enhance the brain targeting and efficacy of the RIV via nasal delivery.

本研究的目的是以环糊精为构件合成超分子储层（即环糊精金属有机框架，MOF），然后以CD-MOF为模板交联获得交联CD框架（CDF），并用龙脑（BO）功能化，以增强利伐斯的明（RIV）的渗透性，促进通过鼻内给药实现脑靶向。利用具有立方体形状的BO修饰CDF（BO-CDF）作为包封RIV的载体，制备了一种鼻腔RIV给药系统（RIV@BO-CDF）。RIV@BO-CDF 的粒径约为 250 nm，载药量达到 15 ± 2 %。BO-CDF改善了RIV的粘附性，提高了RIV的渗透性，大鼠血浆浓度-时间曲线（AUC）、脑AUC和脑内药物浓度峰值分别是口服RIV溶液的1.7倍、2.3倍和8倍。RIV@BO-COF 的相对药物靶向效率百分比（DTE，139.4%）和直接药物转移百分比（DTP，28.3%）表明其具有良好的靶向效率和直接鼻脑给药能力。总之，本研究为基于超分子环糊精的储层通过鼻腔给药增强 RIV 的脑靶向性和药效提供了一种潜在的应用。

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引用次数: 0

Chitosan-melanin complex microsphere: A potential colonic delivery system for protein drugs 壳聚糖-黑色素复合微球：一种潜在的蛋白质药物结肠输送系统

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-21 DOI: 10.1016/j.carbpol.2024.122886

Hongmei Zhao , Xi He , Chengjia Tan , Ali Murad Jakhar , Fuyuan He , Jiahua Ma

The characteristics and performance of chitosan-based colon delivery systems are significantly influenced by the method of preparation. Insect chitosan-melanin complex (CMC) may offer superior attributes over traditional shrimp and crab chitosan (CS) for colon-targeted administration. This study used dung beetle CMC as the carrier matrix and comprehensively examined the impact of various crosslinking techniques on the colonic drug delivery efficacy of microspheres, encompassing drug loading, swelling, drug release behavior, adhesion, enzymatic degradation, and absorption enhancement. The results indicate that F-TPPLC microspheres, crosslinked with a combination of formaldehyde and sodium tripolyphosphate, exhibit superior drug loading capabilities, optimal swelling behavior, and controlled in vitro drug release profiles in the colonic environment, along with excellent adhesion and enzymatic degradation properties within intestinal tract. Notably, these F-TPPLC microspheres increase paracellular permeability, possibly by disrupting the calcium-dependent adhesion junctions. In comparison to commercial CS, CMC demonstrates superior drug encapsulation efficiency, enhanced colonic drug release, adhesion, and absorption promotion, rendering it a favorable candidate as a carrier in colon-targeted drug delivery systems. Consequently, F-TPPLC microspheres derived from CMC are highly suitable for colon drug delivery applications and show promising potential for the oral delivery of peptide and protein-based therapeutics to the colon.

壳聚糖结肠给药系统的特性和性能受到制备方法的很大影响。在结肠靶向给药方面，昆虫壳聚糖-黑色素复合物（CMC）可能比传统的虾蟹壳聚糖（CS）具有更优越的特性。本研究以蜣螂壳聚糖-麦拉宁复合物（CMC）为载体基质，全面考察了各种交联技术对微球结肠给药效果的影响，包括药物负载、溶胀、药物释放行为、粘附、酶降解和吸收增强等方面。结果表明，用甲醛和三聚磷酸钠组合交联的 F-TPPLC 微球在结肠环境中表现出卓越的载药能力、最佳的溶胀行为和可控的体外药物释放曲线，同时在肠道内具有出色的粘附性和酶降解特性。值得注意的是，这些 F-TPPLC 微球可能通过破坏钙依赖性粘附连接，增加了细胞旁通透性。与商用 CS 相比，CMC 表现出更高的药物封装效率，增强了结肠药物释放、粘附和吸收促进作用，使其成为结肠靶向给药系统载体的有利候选材料。因此，由 CMC 制成的 F-TPPLC 微球非常适合结肠给药应用，并显示出向结肠口服多肽和蛋白质类治疗药物的巨大潜力。

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引用次数: 0

Structural analysis and accelerating wound healing function of a novel galactosylated glycosaminoglycan from the snail Helix lucorum 来自蜗牛 Helix lucorum 的新型半乳糖基化氨基糖的结构分析和加速伤口愈合功能

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-21 DOI: 10.1016/j.carbpol.2024.122900

Ya Li , Xingzi Wang , Jiangyan Chen , Luyun Sun , Debing Pu , Lisha Lin , Lan Luo , Xi Gong , Junxue Pu , Mingyi Wu

Diabetic foot ulcers (DFUs) as a nonhealing wound remain a clinical challenge, and the development of pro-healing and cost-effective drugs is in urgent need. Herein, we reported a novel galactosylated glycosaminoglycan (GAG) from the snail Helix lucorum, as an effective pro-healing compound. The snail GAG is composed of a heparan sulfate-like main chain and galactose side chains at C-3 of GlcNAc residue. Its main chain has a repeating disaccharide structure of → 4)-α-D-GlcNAc-(1 → 4)-α-L-IdoA_2S(1 →. This is the first example of glycosaminoglycan with galactose branches from mollusks. Pharmacological experiments showed that the H. lucorum GAG significantly promoted skin wound healing in both healthy and diabetic mice by accelerating granulation tissue regeneration, angiogenesis, and collagen deposition. The distinctive galactosylated substitution may play an important role on its pro-healing activity. Our discovery enriches the diversity of non-anticoagulant heparan sulfate-like glycosaminoglycans, and provides a potential candidate of pro-healing drug for treating diabetic wound.

糖尿病足溃疡（DFUs）作为一种不愈合伤口，仍然是临床上的一大难题，因此急需开发促进愈合且经济有效的药物。在此，我们报告了一种来自蜗牛 Helix lucorum 的新型半乳糖基化氨基糖（GAG），它是一种有效的促愈合化合物。蜗牛 GAG 由硫酸肝素样主链和位于 GlcNAc 残基 C-3 的半乳糖侧链组成。其主链的重复双糖结构为 → 4)-α-D-GlcNAc-(1 → 4)-α-L-IdoA2S(1 →)。这是软体动物中第一个带有半乳糖分支的氨基糖。药理实验表明，H. lucorum GAG 可通过加速肉芽组织再生、血管生成和胶原沉积，显著促进健康小鼠和糖尿病小鼠的皮肤伤口愈合。独特的半乳糖基取代可能对其促进伤口愈合的活性起着重要作用。我们的发现丰富了非抗凝血硫酸肝素类氨基糖的多样性，为治疗糖尿病伤口提供了一种潜在的促进愈合药物候选物。

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引用次数: 0

Melt processing of chemically modified cellulosic fibres with only water as plasticiser: Effects of moisture content and processing temperature 仅用水作为增塑剂对化学改性纤维素纤维进行熔融加工：水分含量和加工温度的影响

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-21 DOI: 10.1016/j.carbpol.2024.122891

Emile R. Engel , Giada Lo Re , Per A. Larsson

To replace petroleum-derived polymers with cellulose fibres, it is desirable to have the option of melt processing. However, upon heating, cellulose degradation typically starts before the material reaches its softening temperature. Alternatives to plastics should also, ideally, be recyclable via existing recycling streams. Here, we address the problem of melt processing cellulose as fibres while preserving recyclability. Native cellulose fibres were partially modified to dialcohol cellulose to impart thermoplastic characteristics. We demonstrate melt processing of these modified fibres with only water as plasticiser. Processability was investigated at selected processing temperatures and initial moisture content by monitoring the axial force of the extruder screws as a rheological indicator. The effects on molecular structure, fibre morphology and material properties were characterised by NMR spectroscopy, microscopy, tensile testing, fibre morphology analysis and X-ray diffraction. When comparing the melt-processed extrudate with handsheets, the already exceptional ductility was further increased. Moderate losses in tensile strength and stiffness were observed and are attributable to a loss of crystallinity and fibre shortening. This is the first report of strong and durable extrudates using cellulosic fibres as the only feedstock. Finally, the potential for recycling the processed material with unmodified fibres by paper recycling procedures was demonstrated.

要想用纤维素纤维替代石油衍生聚合物，最好能选择熔融加工。然而，在加热过程中，纤维素通常会在材料达到软化温度之前开始降解。塑料替代品最好还能通过现有的回收流进行回收。在这里，我们要解决的问题是如何在熔融加工纤维素纤维的同时保持其可回收性。将原生纤维素纤维部分改性为二羟基纤维素，以赋予其热塑性特征。我们展示了仅用水作为增塑剂对这些改性纤维进行熔融加工的过程。在选定的加工温度和初始含水量下，通过监测挤出机螺杆的轴向力作为流变指标，对加工性能进行了研究。核磁共振光谱、显微镜、拉伸测试、纤维形态分析和 X 射线衍射分析了对分子结构、纤维形态和材料特性的影响。将熔融加工挤出物与手板进行比较，本已非常出色的延展性得到了进一步提高。拉伸强度和刚度略有下降，原因是结晶度下降和纤维缩短。这是第一份使用纤维素纤维作为唯一原料生产出坚固耐用的挤出物的报告。最后，还证明了通过纸张回收程序将加工过的材料与未改性纤维一起回收利用的潜力。

{"title":"Melt processing of chemically modified cellulosic fibres with only water as plasticiser: Effects of moisture content and processing temperature","authors":"Emile R. Engel , Giada Lo Re , Per A. Larsson","doi":"10.1016/j.carbpol.2024.122891","DOIUrl":"10.1016/j.carbpol.2024.122891","url":null,"abstract":"<div><div>To replace petroleum-derived polymers with cellulose fibres, it is desirable to have the option of melt processing. However, upon heating, cellulose degradation typically starts before the material reaches its softening temperature. Alternatives to plastics should also, ideally, be recyclable via existing recycling streams. Here, we address the problem of melt processing cellulose as fibres while preserving recyclability. Native cellulose fibres were partially modified to dialcohol cellulose to impart thermoplastic characteristics. We demonstrate melt processing of these modified fibres with only water as plasticiser. Processability was investigated at selected processing temperatures and initial moisture content by monitoring the axial force of the extruder screws as a rheological indicator. The effects on molecular structure, fibre morphology and material properties were characterised by NMR spectroscopy, microscopy, tensile testing, fibre morphology analysis and X-ray diffraction. When comparing the melt-processed extrudate with handsheets, the already exceptional ductility was further increased. Moderate losses in tensile strength and stiffness were observed and are attributable to a loss of crystallinity and fibre shortening. This is the first report of strong and durable extrudates using cellulosic fibres as the only feedstock. Finally, the potential for recycling the processed material with unmodified fibres by paper recycling procedures was demonstrated.</div></div>","PeriodicalId":261,"journal":{"name":"Carbohydrate Polymers","volume":"348 ","pages":"Article 122891"},"PeriodicalIF":10.7,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142538671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delivery system for dexamethasone phosphate based on a Zn2+-crosslinked polyelectrolyte complex of diethylaminoethyl chitosan and chondroitin sulfate 基于二乙氨基乙基壳聚糖和硫酸软骨素的 Zn2+交联聚电解质复合物的地塞米松磷酸盐给药系统

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-20 DOI: 10.1016/j.carbpol.2024.122899

Natallia V. Dubashynskaya , Anton N. Bokatyi , Andrey S. Trulioff , Artem A. Rubinstein , Veronika P. Novikova , Valentina A. Petrova , Elena N. Vlasova , Alexey V. Malkov , Igor V. Kudryavtsev , Yury A. Skorik

Hybrid nano- and microparticles based on metal ion crosslinked biopolymers are promising carriers for the development of drug delivery systems with improved biopharmaceutical properties. In this work, dexamethasone phosphate-containing particles based on chondroitin sulfate and chitosan or diethylaminoethyl chitosan additionally crosslinked with Zn²⁺ were prepared. Depending on the polycation/polyanion ratio in the system, anionic and cationic polyelectrolyte complexes (PECs) were obtained. The anionic Zn²⁺-containing and Zn²⁺-free PECs had sizes of 154 and 180 nm and ζ-potentials of −22.4 and −27.5 mV, respectively. The cationic Zn²⁺-containing and Zn²⁺-free PECs had sizes of 242 and 362 nm and ζ-potentials of 22.4 and 24.7 mV, respectively. The presence of Zn²⁺ in the system significantly prolonged the release of dexamethasone phosphate from the hybrid polyelectrolyte particle. The resulting release profiles of dexamethasone phosphate were in agreement with the Peppas-Sahlin kinetic model, which considers the combined effects of Fickian diffusion and polymer chain relaxation on the drug release rate. It was shown that the prolongation of drug release was mainly due to swelling and relaxation of the Zn²⁺ crosslinked polymers. The developed particles exhibited good mucoadhesive properties and pronounced anti-inflammatory activity, making them attractive candidates for biomedical applications.

基于金属离子交联生物聚合物的混合纳米颗粒和微颗粒是一种很有前景的载体，可用于开发具有更好生物制药特性的给药系统。在这项工作中，制备了基于硫酸软骨素和壳聚糖或二乙胺基乙基壳聚糖并与 Zn2+ 交联的含磷酸地塞米松颗粒。根据体系中的多阳离子/多阴离子比例，可获得阴离子和阳离子聚电解质复合物（PECs）。含 Zn2+ 的阴离子聚电解质复合物和不含 Zn2+ 的聚电解质复合物的尺寸分别为 154 nm 和 180 nm，ζ电位分别为 -22.4 mV 和 -27.5 mV。含 Zn2+ 的阳离子 PEC 和不含 Zn2+ 的 PEC 的尺寸分别为 242 纳米和 362 纳米，ζ电位分别为 22.4 毫伏和 24.7 毫伏。系统中 Zn2+ 的存在大大延长了地塞米松磷酸盐从混合聚电解质颗粒中的释放时间。由此得出的磷酸地塞米松释放曲线与 Peppas-Sahlin 动力学模型一致，该模型考虑了费克扩散和聚合物链松弛对药物释放速率的综合影响。研究表明，药物释放时间的延长主要是由于 Zn2+ 交联聚合物的溶胀和松弛。所开发的颗粒具有良好的粘附性和明显的抗炎活性，因此在生物医学应用中具有吸引力。

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引用次数: 0

A pectic polysaccharide from Typhonii Rhizoma: Characterization and antiproliferative activity in K562 cells through regulating mitochondrial function and energy metabolism 一种来自酪菰的果胶多糖：表征以及通过调节线粒体功能和能量代谢抗 K562 细胞增殖的活性

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-20 DOI: 10.1016/j.carbpol.2024.122897

Xiaodan Qi , Ying Liu , Ying Zhou , Heqi Li , Jingyi Yang , Senyang Liu , Xinyi He , Lei Li , Chunjing Zhang , Haitao Yu

The pectic polysaccharide WTRP-A0.2b (43 kDa) has been isolated from Typhonii rhizoma and analyzed in terms of its structural features, anti-tumor activities and mechanism of action. NMR, FT-IR, monosaccharide composition, and enzymology demonstrate that WTRP-A0.2b is composed of rhamnogalacturonan I (RG-I), rhamnogalacturonan II (RG-II) and homogalacturonan (HG) domains with mass ratios of 3.7:1:1.7, respectively. The RG-I domains contain a highly branched structure that is substituted primarily with β-D-1,4-galactan, α-L-1,5-arabinan, and AG-II. The HG domains contain un-esterified and methyl-esterified and/or acetyl-esterified oligogalacturonides with a degree of polymerization of 1–8. In vitro experiments demonstrate that WTRP-A0.2b inhibits proliferation of K562 cells by inducing mitochondrial damage and suppressing glycolysis. This activity promotes mitochondrial permeability, increases production of reactive oxygen species (ROS), boosts extracellular oxygen consumption and adenosine triphosphate (ATP) content, while it decreases uncoupling protein-2 (UCP2) expression and lactic acid content. Our results provide valuable insight for screening natural polysaccharide-based anti-tumor effects of polysaccharides from Typhonii rhizoma.

从酪氨酸根瘤中分离出果胶多糖 WTRP-A0.2b（43 kDa），并对其结构特征、抗肿瘤活性和作用机制进行了分析。核磁共振、傅立叶变换红外光谱、单糖组成和酶学研究表明，WTRP-A0.2b 由鼠李糖半乳糖醛酸 I（RG-I）、鼠李糖半乳糖醛酸 II（RG-II）和同源半乳糖醛酸（HG）结构域组成，质量比分别为 3.7:1:1.7。RG-I 结构域包含一个高度支化的结构，主要由 β-D-1,4-半乳糖、α-L-1,5-阿拉伯半乳聚糖和 AG-II 取代。HG 结构域包含未酯化、甲基酯化和/或乙酰酯化的低聚半乳糖醛酸，聚合度为 1-8。体外实验证明，WTRP-A0.2b 通过诱导线粒体损伤和抑制糖酵解来抑制 K562 细胞的增殖。这种活性促进线粒体通透性，增加活性氧（ROS）的产生，提高细胞外氧消耗和三磷酸腺苷（ATP）含量，同时降低解偶联蛋白-2（UCP2）的表达和乳酸含量。我们的研究结果为筛选基于天然多糖的酪氨酸根瘤多糖的抗肿瘤作用提供了有价值的见解。

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引用次数: 0

Multifunctional lignin-reinforced cellulose foam for the simultaneous removal of oils, dyes, and metal ions from water 同时去除水中油类、染料和金属离子的多功能木质素强化纤维素泡沫

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-19 DOI: 10.1016/j.carbpol.2024.122890

Zhenrong Tan , Beibei Yang , Weifeng Liu , Dongjie Yang , Xueqing Qiu , Dafeng Zheng

Pollutants emitted by industry pose an emerging threat to ecosystems, human health and native species, which has attracted global attention. At present, most of the biomass-based water remediation materials suffer from the poor mechanical properties, complexity of the modification process, single function and low adsorption capacity. Therefore, a high-strength lignin/cellulose foam absorbent (LCMA) with super-hydrophilic surface was developed for wastewater treatment by using lignin as the skeleton to crosslink cellulose through sol-gel method. Combined with an abundance of reactive functional groups and a highly porous structure, LCMA demonstrated a superior absorption and removal performance for cationic dyes and heavy metal ions, with separation efficiencies exceeding 99.76 % for cationic dyes and 99.85 % for heavy metal ions. Further modification of LCMA by a facile method using polydopamine (PDA) and polyethyleneimine (PEI) imparted superhydrophilicity to the foams. The developed LCMA@PDA@PEI exhibited an impressive immiscible oil-water separation performance and emulsion separation performance (Separation efficiency >99.95 % for immiscible oil-water mixtures and >99.05 % for oil-in-water emulsions). With the capabilities of simultaneous removal for dyes, heavy metal ions and oil pollutants from water, LCMA holds a broad application prospect in the water remediation, especially in the treatment of polluted water with complex components.

工业排放的污染物对生态系统、人类健康和本地物种构成了新的威胁，已引起全球关注。目前，大多数生物质水处理材料都存在机械性能差、改性工艺复杂、功能单一、吸附能力低等问题。因此，本研究以木质素为骨架，通过溶胶-凝胶法交联纤维素，开发出一种具有超亲水性表面的高强度木质素/纤维素泡沫吸附剂（LCMA），用于废水处理。结合丰富的活性官能团和高多孔结构，LCMA 对阳离子染料和重金属离子具有优异的吸收和去除性能，阳离子染料的分离效率超过 99.76%，重金属离子的分离效率超过 99.85%。通过使用聚多巴胺（PDA）和聚乙烯亚胺（PEI）的简便方法对 LCMA 进行进一步改性，使泡沫具有超亲水性。所开发的 LCMA@PDA@PEI 具有出色的不相溶油水分离性能和乳液分离性能（不相溶油水混合物的分离效率为 99.95%，水包油型乳液的分离效率为 99.05%）。LCMA 能够同时去除水中的染料、重金属离子和油类污染物，因此在水处理领域，尤其是在处理成分复杂的污染水体方面具有广阔的应用前景。

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引用次数: 0

Hemp cellulose-based aerogels and cryogels: From waste biomass to sustainable absorbent pads for food preservation 大麻纤维素气凝胶和低温凝胶：从废弃生物质到用于食品保鲜的可持续吸收垫

IF 10.7 1区化学 Q1 CHEMISTRY, APPLIED

Carbohydrate Polymers

Pub Date : 2024-10-19 DOI: 10.1016/j.carbpol.2024.122887

Laura Cabrera-Villamizar , Jéssica Fernanda Pereira , María Castanedo , Amparo López-Rubio , María José Fabra

This study presents a circular economy approach utilizing hemp stems and rice straw, typically perceived as low-value agricultural waste, to develop a sustainable alternative to traditional plastic absorbent pads for food packaging. The development of an active material was achieved through the utilization of hemp cellulose and a bioactive extract isolated from rice straw. In addition to reducing plastic pollution, this material demonstrates the potential to enhance food preservation. This research provides evidence of the benefits of repurposing agricultural by-products to create valuable and environmentally-friendly products. Hemp cellulose was extracted, characterized, and processed to develop stable aerogels and cryogels through supercritical CO₂ drying and freeze-drying. The water stability and internal structure of the materials were guided via TEMPO-mediated oxidation and high-pressure homogenization. Both materials showed versatile physicochemical and mechanical properties. Nevertheless, with higher water sorption (2.20 mL/g), minimal dimensional changes, and lower shrinkage, cryogels were suitable for meat absorbent pad application. To enhance the cryogels functionality, they were impregnated with a rice straw bioactive extract in two different concentrations. The incorporation of the extract did not affect the structure of the cryogels, improved their mechanical properties and the antioxidant activity remained stable after drying (63.89–78.96 %). Finally, the performance of the developed materials was compared to commercial plastic pads and pristine meat preservation challenge test during 9 days at refrigeration conditions. The incorporation of rice straw extract improved meat color preservation. While moderate extract concentrations (75 mg/g) showed a protective effect against lipid oxidation, higher levels (187.5 mg/g) induced pro-oxidant reactions. This research highlights the potential of hemp cellulose-based cryogels as sustainable and functional packaging materials for meat products.

本研究提出了一种循环经济方法，利用通常被视为低价值农业废弃物的大麻茎和稻草，开发出一种可持续的食品包装塑料吸水垫替代品。通过利用大麻纤维素和从稻草中分离出的生物活性提取物，开发出了一种活性材料。除了减少塑料污染，这种材料还展示了提高食品保鲜的潜力。这项研究证明了重新利用农业副产品创造有价值的环保产品的益处。研究人员对大麻纤维素进行了提取、表征和加工，并通过超临界二氧化碳干燥和冷冻干燥开发出稳定的气凝胶和冷凝胶。通过 TEMPO 介导的氧化和高压均质化，对材料的水稳定性和内部结构进行了指导。这两种材料都显示出多种物理化学和机械性能。然而，由于低温凝胶具有较高的吸水性（2.20 mL/g）、最小的尺寸变化和较低的收缩率，因此适合用于肉类吸水垫。为了增强低温凝胶的功能，在低温凝胶中浸渍了两种不同浓度的稻草生物活性提取物。提取物的加入不会影响低温凝胶的结构，还能改善其机械性能，而且抗氧化活性在干燥后保持稳定（63.89%-78.96%）。最后，在 9 天的冷藏条件下，将所开发材料的性能与商用塑料垫和原始肉类保鲜挑战测试进行了比较。稻草提取物的加入提高了肉的保色效果。中等浓度的提取物（75 毫克/克）对脂质氧化有保护作用，而较高浓度的提取物（187.5 毫克/克）则会诱发促氧化反应。这项研究凸显了以大麻纤维素为基础的低温凝胶作为肉类产品的可持续功能性包装材料的潜力。

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引用次数: 0