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Can XunTian Tai Chi intervention improve the level of emotional regulation of crew members in the Controlled Ecological Life Support System? 训天太极干预能否提高受控生态生命维持系统船员情绪调节水平?
Q2 SPORT SCIENCES Pub Date : 2023-09-01 DOI: 10.1016/j.smhs.2023.07.009
Feizhou Tong , Chaoming Wu , Lili Wang , Xiaolu Jing , Shiyun Wu , Junzhi Sun , Yong Hu , Jie Li , Yanlei Wang , Yinghui Li

To explore the appropriate exercise methods and means for astronauts in confined and small isolation conditions, a set of XunTian Tai Chi suitable for the spaceflight workforce was created, with the aim of discovering the practical effects of XunTian Tai Chi and providing a scientific basis for the subsequent development of new astronaut health maintenance techniques with Chinese characteristics. Using the Controlled Ecological Life Support System (CELSS) as a research platform, we observed the changes in a crew member’s emotion regulation-related indexes during 180 days of working and living in a confined isolation chamber through periodic interventions of the XunTian Tai Chi and conducted statistical analyses. During the 180-day cabin mission, expression suppression, cognitive reappraisal, attention index, and relaxation index were all lower than those before entering the cabin, suggesting that the crew member’s emotion regulation ability decreased during the in-cabin mission. A single Tai Chi exercise could cause favorable changes in the indicators, positively affecting the crew member's emotional regulation. The attention and relaxation indices of the occupants were improved significantly by both single and periodic Tai Chi exercises. After the Tai Chi exercise cycle, the results of each index showed a certain degree of effect. The 180-day ground-based simulation of Tai Chi in the confinement of a space capsule positively affects the occupant’s emotional regulation.

为探索适合航天员在密闭小隔离条件下的锻炼方法和手段,创建了一套适合航天工作人员的训天太极拳,旨在发现训天太极拳的实际效果,为后续开发具有中国特色的航天员健身新技术提供科学依据。以可控生态生命支持系统(CELSS)为研究平台,通过“训天太极”的周期性干预,观察一名机组人员在密闭隔离舱工作和生活180天期间情绪调节相关指标的变化,并进行统计分析。在180天的客舱任务中,机组人员的表情抑制、认知重评价、注意力指数和放松指数均低于进入客舱前的水平,说明机组人员在客舱任务期间情绪调节能力有所下降。单次太极拳运动可使各项指标发生有利变化,对机组人员的情绪调节产生积极影响。单次和定期太极练习均能显著改善患者的注意力和放松指数。经过一个太极运动周期后,各项指标的结果均显示出一定程度的效果。在太空舱内进行的为期180天的地面太极模拟对居住者的情绪调节有积极影响。
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引用次数: 0
Assessment of metabolic flexibility by measuring maximal fat oxidation during submaximal intensity exercise: Can we improve the analytical procedures? 通过测量亚最大强度运动中最大脂肪氧化来评估代谢柔韧性:我们能改进分析程序吗?
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.02.001
Isaac A. Chávez-Guevara

Assessment of maximal fat oxidation rate (MFO) during a submaximal exercise test has been employed by many studies to investigate the differences in metabolic flexibility (MetFlex) across several populations. Nevertheless, many incorrect assumptions and methodological limitations exist in the procedures employed by previous studies, which might lead to misinterpretation of the reported findings. Considering the data retrieved from 19 trained men (Age: [27 ​± ​4] years; %Body fat: [16.4 ​± ​4.5]%; maximal oxygen consumption: [55.8 ​± ​5.3] mL·kg−1·min−1) who performed a graded exercise test over a motor-driven treadmill, this opinion paper shows that MFO alone does not perfectly capture the MetFlex in response to submaximal intensity exercise and recommend a novel index that considers both fat oxidation and energy expenditure modifications for an accurate examination of MetFlex.

许多研究采用亚最大运动测试期间的最大脂肪氧化率(MFO)评估来研究几个人群的代谢灵活性(MetFlex)差异。尽管如此,以前的研究所采用的程序中存在许多不正确的假设和方法上的局限性,这可能会导致对所报告的研究结果的误解。考虑到从19名受过训练的男性(年龄:[27​±​4] 年;%身体脂肪:[16.4​±​4.5]%;最大耗氧量:[55.8​±​5.3]mL·kg−1·min−1)在电动跑步机上进行了分级运动测试,该意见书表明,单独的MFO并不能完美地捕捉亚最大强度运动时的MetFlex,并推荐了一种同时考虑脂肪氧化和能量消耗变化的新指数,以准确检查MetFlex。
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引用次数: 0
A remote, fully oriented personalized program of physical exercise for women in follow-up after breast cancer treatment improves body composition and physical fitness 为乳腺癌治疗后随访的女性提供远程、完全定向的个性化体育锻炼计划,可改善身体成分和体质
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.03.005
Édipo G. França-Lara , Saulo H. Weber , Ricardo A. Pinho , José Claudio Casali-da-Rocha , Selene Elifio-Esposito

This study aimed to evaluate the efficacy of an individualized remote exercise program on the improvement of body composition and physical fitness of a heterogeneous group of patients who completed breast cancer treatment. This prospective study included 107 women aged 18 to 60, shortly after curative treatment for localized breast cancer, at the Erasto Gaertner Cancer Hospital (HEG) in Curitiba, PR, Brazil. Body composition, maximal oxygen consumption, and muscle resistance were evaluated after nine months of intervention while considering adherence to the program, level of physical activity, presence of binge eating disorder, tumor classification, and treatment type. Seventy-eight women (72.8%) adhered to the training program. Adherent participants showed significant changes in body mass ([-4.3 ​± ​3.6] kg; p ​< ​0.000 1), body mass index ([-1.6 ​± ​1.5] kg·m−2; p ​< ​0.000 1), body fat (−3.4% ​± ​3.1%; p ​< ​0.000 1), maximal oxygen consumption ([7.5 ​± ​2.0] ml·kg−1·min−1); p ​< ​0.000 1), and abdominal resistance ([11.2 ​± ​2.8] reps; p ​< ​0.000 1). In contrast, these variables did not change significantly in the non-adherent group. Among the adherent participants, those subclassified in the severe binge group showed a more noticeable reduction in body mass, body mass index, and body fat (p ​< ​0.05) than those in the non-binge group. Individualized remotely-guided physical exercise programs can improve the body composition and physical fitness of women undergoing post-breast cancer surveillance, regardless of pathological history or treatment.

本研究旨在评估个体化远程锻炼计划对完成癌症治疗的异质性患者群体的身体成分和身体素质的改善效果。这项前瞻性研究包括107名年龄在18至60岁的女性,她们在巴西库里蒂巴的Erasto Gaertner癌症医院(HEG)接受局部乳腺癌症治疗后不久。在干预9个月后,评估身体成分、最大耗氧量和肌肉阻力,同时考虑对该计划的依从性、体力活动水平、是否存在暴饮症、肿瘤分类和治疗类型。78名妇女(72.8%)参加了培训计划。依从性参与者的体重发生了显著变化([-4.3​±​3.6]千克;p​<;​0.0001),体重指数([-1.6​±​1.5]kg·m−2;p​<;​0.0001),体脂(−3.4%​±​3.1%;p​<;​0.0001),最大耗氧量([7.5​±​2.0]ml·kg−1·min−1);p​<;​0.0001)和腹部阻力([11.2​±​2.8]次;p​<;​0.0001)。相反,这些变量在非粘连组中没有显著变化。在坚持的参与者中,那些被分为严重狂欢组的参与者在体重、体重指数和体脂方面表现出更显著的下降(p​<;​0.05)显著高于非暴饮组。个性化的远程指导体育锻炼计划可以改善接受癌症后监测的女性的身体成分和身体素质,无论其病理史或治疗情况如何。
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引用次数: 0
The efficacy of a verification stage for determining V˙O2max and the impact of sampling intervals 验证阶段对确定V˙O2max的有效性和采样间隔的影响
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.04.001
Emily J. Kontos, Nicholas D. Luden, Stephanie Kurti, Christopher J. Womack

It is unknown whether oxygen uptake (V̇O2) sampling intervals influence the efficacy of a verification stage following a graded exercise test (GXT). Fifteen females and 14 males (18–25 years) completed a maximal treadmill GXT. After a 5 ​min recovery, the verification stage began at the speed and grade corresponding with the penultimate stage from the GXT. Maximal oxygen consumption (V̇O2max) from the incremental GXT (iV̇O2max) and V̇O2max from the verification stage (verV̇O2max) were determined using 10 seconds (s), 30 ​s, and 60 ​s from breath ​× ​breath averages. There was no main effect for V̇O2max measure (iV̇O2maxvs. verV̇O2max) 10 ​s ([47.9 ​± ​8.31] ml∙kg−1∙min−1 vs [48.85 ​± ​7.97] ml∙kg−1∙min−1), 30 ​s ([46.94 ​± ​8.62] ml∙kg−1∙min−1 vs [47.28 ​± ​7.97] ml∙kg−1∙min−1), and 60 ​s ([46.17 ​± ​8.62] ml∙kg−1∙min−1 vs [46.00 ​± ​8.00] ml∙kg−1∙min−1]. There was a stage ​× ​sampling interval interaction as the difference between (verV̇O2max−iV̇O2max) was greater for 10-s than 60-s sampling intervals. The verV̇O2max was > 4% higher than iV̇O2maxin 31%, 31%, and 17% of the tests for the 10-s, 30-s, and 60-s sampling intervals respectively. Sensitivity for the plateau was < 30% for 10-s, 30-s, and 60-s sampling intervals. Specificity ranged from 44% to 60% for all sampling intervals. Sensitivity for heart rate ​+ ​respiratory exchange ratio was > 90% for all sampling intervals; while specificity was < 25%. Findings from the present study suggest that the efficacy of verification stages for eliciting a higher V̇O2max may be influenced by the sampling interval utilized.

目前尚不清楚吸氧量(V̇O2)采样间隔是否会影响分级运动测试(GXT)后验证阶段的疗效。15名女性和14名男性(18-25岁)完成了最大跑台GXT。在5​min恢复,验证阶段以与GXT倒数第二阶段相对应的速度和等级开始。增量GXT的最大耗氧量(V̇O2max)(iV 775 O2max​s、 和60​s来自呼吸​×​呼吸平均值。对V̇O2max测量没有主要影响(iV 775 O2maxvs.verV 771 O2max)10​s([47.9​±​8.31]ml∙kg−1∙min−1 vs[48.85​±​7.97]ml∙kg−1∙min−1),30​s([46.94​±​8.62]ml∙kg−1∙min−1 vs[47.28​±​7.97]ml∙kg−1∙min−1)和60​s([46.17​±​8.62]ml∙kg−1∙min−1 vs[46.00​±​8.00]毫升∙千克−1∙分钟−1]。有一个舞台​×​采样间隔相互作用,因为(verV̇O2max−iV 775 O2max)之间的差异在10s大于60s的采样间隔。verV̇O2max为>;在10秒、30秒和60秒的采样间隔内,iV̇O2maxin分别比31%、31%和17%的测试高4%。对平台的敏感性为<;10秒、30秒和60秒采样间隔为30%。所有采样间隔的特异性在44%至60%之间。心率敏感性​+​呼吸交换率>;所有采样间隔为90%;而特异性<;25%。本研究的结果表明,引发更高V̇O2max的验证阶段的有效性可能受到所使用的采样间隔的影响。
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引用次数: 0
Effects of high-/low-temperature and high-altitude hypoxic environments on gut microbiota of sports people: A retrospective analysis 高/低温和高海拔缺氧环境对运动人群肠道微生物群的影响:回顾性分析
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.03.003
Xue Geng , Chaoyi Qu , Lina Zhao , Jianhong Zhang , Peng Huang , Derun Gao , Qiangman Wei , Fei Qin , Jiexiu Zhao

As an invisible “endocrine organ”, gut microbiota is widely involved in the regulation of nervous system, endocrine system, circulatory system, and digestive system. It is also closely related to host health and the occurrence of many chronic diseases. Relevant literature shows that high temperature, low temperature, and high-altitude hypoxia may have negative effects on commensal microorganisms. The stimulation of exercise may aggravate this reaction, which is related to the occurrence of exercise-induced fever and gastrointestinal and respiratory diseases. The intervention of probiotics can alleviate the above problems to a certain extent. Therefore, this paper takes exercise in a special environment as the starting point, deeply analyses the intervention effect and potential mechanism of probiotics, and provides the theoretical basis and reference for follow-up research and application of probiotics in sports science.

肠道微生物群作为一种无形的“内分泌器官”,广泛参与神经系统、内分泌系统、循环系统和消化系统的调节。它还与宿主健康和许多慢性病的发生密切相关。相关文献表明,高温、低温和高海拔缺氧可能对共生微生物产生负面影响。运动的刺激可能会加剧这种反应,这与运动性发热以及胃肠道和呼吸道疾病的发生有关。益生菌的干预可以在一定程度上缓解上述问题。因此,本文以特殊环境下的运动为切入点,深入分析益生菌的干预效果和潜在机制,为益生菌在体育科学中的后续研究和应用提供理论依据和参考。
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引用次数: 0
Exercise precision medicine for type 2 diabetes: Targeted benefit or risk? 2型糖尿病精准运动药物:目标效益还是风险?
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.02.003
Shenglong Le , Moritz Schumann , Siman Lei , Wu Yao , Sulin Cheng

Concurrent exercise and metformin administration may reduce the acute and chronic effects of exercise on glucose metabolism in the patients with type 2 diabetes (T2D). However, several studies suggest that combing metformin and exercise treatment may have neither additive effect nor even cause adverse effects in T2D patients. This case report aimed to highlight the challenges associated with prescribing exercise to type 2 diabetes patients undergoing metformin treatment. A 67-years old woman was followed-up for five months, including assessment of the acute and chronic glucose and lactate metabolism induced by concomitant exercise and metformin. The findings were four-fold: 1) During a high-intensity interval training bout, blood glucose systematically decreased, while blood lactate concentrations fluctuated randomly; 2) Basal blood lactate levels were well above 2 mmol/L on days with medication only; 3) Combined exercise and metformin administration induced additive effects on the normalization of glucose and 4) high levels of physical activity had a positive impact on the continuous glucose fluctuations, while decreased levels of physical activity induced a large fluctuation of glucose due to home confinement of an infectious disease caused by the SARS-CoV-2 virus. Our findings showed that when combined with exercise and metformin treatment for T2D patients, exercise may contribute to improving glycemic control while metformin may elevate lactate levels in the long term. The observed results underline the need to prescribe exercise and monitor lactate levels for reducing possible risks associated with metformin treatment and reinforce the importance of tailoring exercise therapy.

同时运动和二甲双胍给药可以减少运动对2型糖尿病(T2D)患者葡萄糖代谢的急性和慢性影响。然而,几项研究表明,二甲双胍与运动治疗相结合可能对T2D患者既没有相加作用,甚至不会造成不良反应。本病例报告旨在强调为接受二甲双胍治疗的2型糖尿病患者开具运动处方的相关挑战。一名67岁的女性接受了五个月的随访,包括评估伴随运动和二甲双胍诱导的急性和慢性葡萄糖和乳酸代谢。研究结果有四个方面:1)在高强度间歇训练中,血糖系统性下降,而血乳酸浓度随机波动;2) 在仅用药的日子里,基础血乳酸水平远高于2mmol/L;3) 运动和二甲双胍联合给药对血糖正常化产生了相加效应,4)高水平的体育活动对血糖的持续波动产生了积极影响,而由于严重急性呼吸系统综合征冠状病毒2型病毒引起的传染病的家庭禁闭,体育活动水平的降低导致血糖的大幅波动。我们的研究结果表明,当结合运动和二甲双胍治疗T2D患者时,运动可能有助于改善血糖控制,而二甲双胍可能会长期提高乳酸水平。观察到的结果强调了制定运动处方和监测乳酸水平的必要性,以降低二甲双胍治疗的可能风险,并强调了量身定制运动疗法的重要性。
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引用次数: 0
Sport and physical exercise in sustainable mental health care of common mental disorders: Lessons from the COVID-19 pandemic 体育锻炼在常见精神障碍可持续精神卫生保健中的作用:来自2019冠状病毒病大流行的经验教训
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.01.005
Klaus W. Lange, Yukiko Nakamura, Andreas Reissmann

The large-scale disruptions to physical activity during the coronavirus pandemic have been found to be a leading predictor of common mental disorders. In addition, regular physical exercise has been found to alleviate anxiety, sadness and depression during the pandemic. These findings, together with numerous studies published before the pandemic on the effects of physical activity on mental health, should be considered in the provision of mental health care following the pandemic. Cross-sectional research has revealed that all types of exercise and sport are associated with a reduced mental health burden. Therefore, the effectiveness of exercise and sport participation in sustainable mental health care as well as the causal relationship between exercise, psychosocial health and common mental disorders merit further investigation. Physical activity and sport, with their global accessibility, significant and clinically meaningful efficacy as well as virtual absence of adverse effects, offer a promising option for the promotion of mental health, including the prevention and treatment of common mental disorders. Physical exercise and sport are likely to become valuable public mental health resources in the future.

冠状病毒大流行期间身体活动的大规模中断被发现是常见精神障碍的主要预测因素。此外,人们发现,在疫情期间,定期体育锻炼可以缓解焦虑、悲伤和抑郁。这些发现,加上疫情前发表的关于体育活动对心理健康影响的大量研究,应在疫情后提供心理健康护理时予以考虑。横断面研究表明,所有类型的锻炼和运动都与减轻心理健康负担有关。因此,运动和体育参与在可持续心理健康护理中的有效性,以及运动、心理健康和常见精神障碍之间的因果关系值得进一步研究。体育活动和体育运动具有全球可及性、显著和临床意义的疗效以及几乎没有副作用,为促进心理健康,包括预防和治疗常见精神障碍,提供了一个很有前途的选择。体育锻炼和体育运动很可能在未来成为宝贵的公共心理健康资源。
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引用次数: 1
Effect of aerobic exercise on GRP78 and ATF6 expressions in mice with non-alcoholic fatty liver disease 有氧运动对非酒精性脂肪性肝病小鼠GRP78和ATF6表达的影响
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2022.11.002
Junhan Li , Lei Huang , Wei Xiong , Chun Gu , Shuling Zhang , Xiali Xue

Nonalcoholic fatty liver disease (NAFLD) is a prevalent medical condition with an ever-growing trend. Although multiple intracellular mechanisms are involved, endoplasmic reticulum (ER) stress has been demonstrated to play a significant role in the genesis and progression. Most of the research supports the advantages of exercise for NAFLD. However, little is known about the molecular mechanism(s) that underpin the effectiveness of exercise training in NAFLD. This study aimed to identify how aerobic exercise affected hepatic ER stress in a mouse NAFLD model. In this study, the mice were fed either a standard diet (SD) or a high-fat diet (HFD) for 17 weeks. HFD mice were trained on a treadmill during the last eight weeks. All animals were tested for serum levels of biochemical assays, protein expression, and gene expression. The hematoxylin and eosin, Oil red O, and immunohistochemistry staining were also performed. The results indicated that a high-fat diet generated NAFLD, with serum lipid disruption and hepatic function impairment, and increased GRP78 and ATF6 expressions. However, aerobic training reversed the majority of these alterations. It is concluded that NAFLD appears to be associated with hepatic ER stress response, and aerobic exercise mitigates NAFLD via lowering ER stress proteins GRP78 and ATF6.

非酒精性脂肪肝(NAFLD)是一种流行的疾病,并有不断增长的趋势。尽管涉及多种细胞内机制,但内质网(ER)应激已被证明在其发生和发展中发挥着重要作用。大多数研究支持运动对NAFLD的好处。然而,对支持NAFLD运动训练有效性的分子机制知之甚少。本研究旨在确定有氧运动如何影响小鼠NAFLD模型中的肝脏ER应激。在这项研究中,给小鼠喂食标准饮食(SD)或高脂肪饮食(HFD)17周。在过去的八周里,HFD小鼠在跑步机上接受训练。对所有动物的血清生化测定水平、蛋白质表达和基因表达进行测试。苏木精和伊红、油红O和免疫组织化学染色也进行了检测。结果表明,高脂肪饮食会产生NAFLD,伴有血脂紊乱和肝功能损害,并增加GRP78和ATF6的表达。然而,有氧训练扭转了大部分的变化。因此,NAFLD似乎与肝脏ER应激反应有关,有氧运动通过降低ER应激蛋白GRP78和ATF6来减轻NAFLD。
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引用次数: 0
The burden of prolonged sedentary behavior imposed by uberization 乘车带来的长时间久坐行为的负担
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.02.005
Thalles Guilarducci Costa , Vinnycius Nunes de Oliveira , Douglas Assis Teles Santos , Ricardo Borges Viana , Marilia Santos Andrade , Rodrigo Luiz Vancini , Katja Weiss , Beat Knechtle , Claudio Andre Barbosa de Lira

Mobility applications are rapidly growing in cities worldwide due to their convenience and low cost. Mobility applications drivers experience vast flexibility in work hours, often work longer than in fixed-hours jobs, and can constantly transport passengers in their vehicles for up to 12 h; after this, they must go offline for eight consecutive hours before driving again. Nonetheless, drivers have found an easy way around this limitation by switching to other apps and continuing driving. This burden of prolonged work can increase sedentary behavior among mobility applications drivers. Sedentary behavior is any waking activity in which the individual expends 1.5 metabolic equivalents (METs) or less while sitting or reclining. This behavior can increase the risk of detrimental effects on health. In this opinion article, we aim to discuss the possible effects of the burden of prolonged work on the sedentary behavior of mobility applications drivers and propose possible strategies to face this concerning situation.

移动应用由于其便利性和低成本而在全球城市中迅速增长。移动应用程序驾驶员在工作时间上具有巨大的灵活性,通常工作时间比固定时间的工作时间长,并且可以在车内持续运送乘客长达12小时;在此之后,他们必须连续离线八个小时才能再次驾驶。尽管如此,司机们还是找到了一种绕过这一限制的简单方法,即切换到其他应用程序并继续驾驶。这种长时间工作的负担会增加移动应用程序驾驶员的久坐行为。久坐行为是指个人在坐着或斜倚时消耗1.5个或更少代谢当量(MET)的任何清醒活动。这种行为会增加对健康造成有害影响的风险。在这篇观点文章中,我们旨在讨论长时间工作的负担对移动应用程序驾驶员久坐行为的可能影响,并提出应对这一令人担忧的情况的可能策略。
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引用次数: 0
Non-enzymatic antioxidant blood plasma profile in the period of high training loads of elite speed skaters in the altitude 高原优秀速滑运动员高训练负荷时期血浆非酶抗氧化特征
Q2 SPORT SCIENCES Pub Date : 2023-06-01 DOI: 10.1016/j.smhs.2023.02.002
Elena Proskurnina , Dmitry Martynov , Andrey Yakushkin , Irina Zelenkova

At the altitude, hypoxia and training load are key factors in the development of oxidative stress. Altitude-induced oxidative stress is developed due to the depletion of antioxidant potential. In the current study, we examined the non-enzymatic antioxidant profile of blood plasma in 7 males and 5 females specializing in speed skating at a 21-day training camp at 1 850 ​m above sea level. Training included: cycling, roller skating, ice skating, strength training, and special training. At the start point and the endpoint, total hemoglobin mass (tHb-mass), hemoglobin concentration, and circulating blood volume were determined. Antioxidant profiles, hypoxic doses, hypoxic impulses, and training impulses were assessed at 3, 6, 10, 14, and 18 days. Antioxidant profiles consisting of “urate” and “thiol” parts were registered with chemiluminometry. In the training dynamics, antioxidant parameters changed individually, but in total there was a decrease in the “urate” capacity by a factor of 1.6 (p ​= ​0.001) and an increase in the “thiol” capacity by a factor of 1.8 (p ​= ​0.013). The changes in “urate” capacity positively correlated (rS ​= ​0.40) and the changes in “thiol” capacity negatively correlated (rS ​= ​−0.45) with changes in tHb-mass. Both exercise and hypoxic factors affect the antioxidant parameters bidirectionally. They correlated with a decrease in thiol capacity and with an increase in urate capacity. The assessment of the non-enzymatic antioxidant profile can be a simple and useful addition to screening the reactive oxygen species homeostasis and can help choose the personalized training schedule, individualize recovery and ergogenic support.

在高原,缺氧和训练负荷是氧化应激发展的关键因素。高原诱导的氧化应激是由于抗氧化潜力的耗尽而产生的。在目前的研究中,我们在1 850的21天训练营中,对7名专门从事速度滑冰的男性和5名女性的血浆中的非酶抗氧化剂进行了检测​海拔m。训练包括:自行车、轮滑、滑冰、力量训练和专项训练。在起始点和终点,测定总血红蛋白质量(tHb质量)、血红蛋白浓度和循环血容量。在第3天、第6天、第10天、第14天和第18天评估抗氧化剂概况、缺氧剂量、缺氧冲动和训练冲动。用化学发光法记录了由“尿酸盐”和“硫醇”部分组成的抗氧化剂图谱。在训练动力学中,抗氧化参数单独变化,但总的来说,“尿酸盐”能力下降了1.6倍(p​=​0.001),“硫醇”容量增加1.8倍(p​=​0.013)。“尿酸盐”容量的变化呈正相关(rS​=​0.40)和“硫醇”容量的变化呈负相关(rS​=​−0.45)随tHb质量的变化而变化。运动和低氧因素都会双向影响抗氧化参数。它们与硫醇容量的降低和尿酸盐容量的增加相关。非酶促抗氧化剂谱的评估可以是筛选活性氧稳态的一个简单而有用的补充,并有助于选择个性化的训练计划、个性化的恢复和工效学支持。
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Sports Medicine and Health Science
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