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Proceedings MEMS 98. IEEE. Eleventh Annual International Workshop on Micro Electro Mechanical Systems. An Investigation of Micro Structures, Sensors, Actuators, Machines and Systems (Cat. No.98CH36176最新文献

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Micromachined needles for the transdermal delivery of drugs 经皮给药用微机械针
S. Henry, D. McAllister, Mark G. Allen, M. Prausnitz
Although modern biotechnology has produced extremely sophisticated and potent drugs, many of these compounds cannot be effectively delivered using current drug delivery techniques (e.g., pills and injections). Administration across skin by transdermal drug delivery is an attractive alternative, but it is limited by the remarkably poor permeability of the skin. Because the primary barrier to transport is located in the upper 10-15 /spl mu/m of skin, and because nerves are only found in deeper tissue, we made arrays of microneedles long enough to cross the permeability barrier but not so long that they stimulate nerves, thereby causing no pain. These microneedles were fabricated using the Black Silicon Method, which is a reactive ion etching process in which an SF/sub 6//O/sub 2/ plasma etches silicon anisotropically. When inserted into skin in vitro, these microneedles demonstrated excellent mechanical properties and enhanced skin permeability to calcein, a model drug, by up to four orders of magnitude. Limited tests on humans demonstrated that microneedles were painless.
尽管现代生物技术已经生产出极为复杂和有效的药物,但许多这些化合物不能通过目前的药物输送技术(例如药丸和注射)有效地输送。经皮给药是一种有吸引力的替代方法,但它受到皮肤渗透性差的限制。由于运输的主要屏障位于皮肤的上部10-15 /spl μ m,并且神经只存在于更深的组织中,因此我们制作了足够长的微针阵列,以穿过渗透性屏障,但不会太长而刺激神经,从而不会引起疼痛。这些微针是用黑硅法制作的,这是一种反应离子蚀刻工艺,其中SF/sub 6//O/sub 2/等离子体各向异性蚀刻硅。当植入体外皮肤时,这些微针表现出优异的机械性能,并提高了皮肤对钙黄蛋白(一种模型药物)的渗透性,提高了4个数量级。有限的人体试验表明,微针是无痛的。
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引用次数: 123
A one-body MEMS device composed of mutually insulated metallic parts-fabrication processes for a microactuator for high-density hard disk drives 一种由相互绝缘金属部件组成的单体MEMS器件——高密度硬盘驱动器微致动器的制造工艺
S. Nakamura, K. Suzuki, H. Fujita, T. Numazawa, H. Takada
Micromachining processes are developed to fabricate a high-aspect-ratio-microstructure (HARMS) actuator for head positioning system of Hard Disk Drives (HDDs) to increase the recording density of HDDs. The actuator is driven by electrostatic force and it has multiple parallel plate electrodes. Our process is to fabricate high-aspect-ratio gap using electroplated sacrificial layer. The process is very attractive to increase the generating force of the electrostatic actuator. Another process is to fabricate a one-body MEMS device composed of mutually insulated metallic parts. These process are essential to realize a compact MEMS device such as a piggy-back microactuator of HDDs.
为提高硬盘驱动器的记录密度,开发了一种用于硬盘驱动器头部定位系统的高纵横比微结构驱动器(HARMS)的微加工工艺。该驱动器由静电力驱动,具有多个平行的平板电极。我们的工艺是利用电镀牺牲层制造高纵横比的间隙。该工艺对提高静电致动器的产生力非常有吸引力。另一种工艺是制造由相互绝缘的金属部件组成的一体MEMS器件。这些工艺对于实现小型MEMS器件(如hdd的背负式微致动器)至关重要。
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引用次数: 5
Micro balloon actuators for aerodynamic control 用于气动控制的微型气球致动器
C. Grosjean, G.B. Lee, W. Hong, Y. Tai, C. Ho
A robust, large-force, large-deflection micro balloon actuator for aerodynamic (manoeuvring) control of transonic aircraft has been developed. Using a novel process, high yield linear arrays of silicone balloons on a robust silicon substrate have been fabricated that can deflect vertically in excess of one mm. Balloon actuators have been tested under cyclic conditions to assess reliability. The actuators have been characterized in a wind tunnel to assess their suitability as aerodynamic control surfaces and flight-tested on a jet fighter to assess their resistance to varied temperatures and pressures at high velocity.
研制了一种用于跨声速飞行器气动(机动)控制的鲁棒、大力、大挠度微气球作动器。利用一种新颖的工艺,在坚固的硅衬底上制造了高产量的硅气球线性阵列,可以垂直偏转超过1毫米。气球执行器已经在循环条件下进行了测试,以评估可靠性。执行器已经在风洞中进行了表征,以评估其作为气动控制面的适用性,并在喷气式战斗机上进行了飞行测试,以评估其在高速下对不同温度和压力的抵抗力。
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引用次数: 62
Diamond microstructure replicas from silicon masters 钻石微观结构的复制品从硅大师
H. Björkman, P. Rangsten, U. Simu, J. Karlsson, P. Hollman, K. Hjort
We are developing a microstructure technology for thick film diamond replicas, using deposition by hot filament CVD on microstructured silicon. This technology is primarily intended to make micromechanical structures for building-sets, fluidic cooling systems, systems for biochemical analyses and processes, and moulds for thermoplastic microstructures. In the thick film deposition on trenches in silicon, complete filling was possible with an aspect ratio up to 1.6. At higher aspect ratios, voids or channels are formed within the diamond replica. Ridges, trenches and capillary channels with high resolution coverage and low roughness, rms<2 nm, were created. Demonstrator structures for microfluidic, building-sets and polymer moulding applications are presented.
我们正在开发一种厚膜金刚石复制品的微结构技术,使用热丝CVD沉积在微结构硅上。该技术主要用于制造建筑装置、流体冷却系统、生化分析和过程系统以及热塑性微结构模具的微机械结构。在硅沟槽上的厚膜沉积中,宽高比可达1.6,完全填充。在较高的纵横比下,在钻石复制品内形成空隙或通道。形成了高分辨率覆盖、低粗糙度(rms<2 nm)的山脊、沟槽和毛细通道。展示了微流体、建筑装置和聚合物成型应用的演示结构。
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引用次数: 8
A suspended microchannel with integrated temperature sensors for high-pressure flow studies 一个带有集成温度传感器的悬浮微通道,用于高压流动研究
S. Wu, J. Mai, Y. Zohar, Y. Tai, C. Ho
A freestanding microchannel, with integrated temperature sensors, has been developed for high-pressure flow studies. These microchannels are approximately 20 /spl mu/m/spl times/2 /spl mu/m/spl times/4400 /spl mu/m, and are suspended above 80 /spl mu/m deep cavities, bulk micromachined using BrF/sub 3/ dry etch. The calibration of the lightly boron-doped thermistor-type sensors shows that the resistance sensitivity of these integrated sensors is parabolic with respect to temperature and linear with respect to pressure. Volumetric flow rates of NZ in the microchannel were measured at inlet pressures up to 578 psig. The discrepancy between the data and theory results from the flow acceleration in a channel, the nonparabolic velocity profile, and the bulging of the channel. Bulging effects were evaluated by using incompressible water flow measurements, which also measures 1.045/spl times/10/sup -3/N-s/m/sup 2/ for the viscosity of DI water. The temperature data from sensors on the channel shows the heating of the channel due to the friction generated by the high-pressure flow inside.
一种带有集成温度传感器的独立微通道已被开发用于高压流动研究。这些微通道约为20 /spl mu/m/spl倍/2 /spl mu/m/spl倍/4400 /spl mu/m,悬浮在80 /spl mu/m深的空腔之上,使用BrF/sub 3/干蚀刻进行批量微加工。对轻硼掺杂热敏电阻型传感器的校准表明,这些集成传感器的电阻灵敏度对温度呈抛物线型,对压力呈线性。在进口压力高达578 psig时,测量了微通道中NZ的体积流速。数据与理论的差异是由通道内的流动加速度、非抛物速度分布和通道的胀形造成的。通过不可压缩水流测量来评估膨胀效果,也测量了去水的粘度为1.045/spl倍/10/sup -3/N-s/m/sup 2/。通道上传感器的温度数据显示,由于内部高压流动产生的摩擦,通道加热。
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引用次数: 58
3D micro-structures folded by Lorentz force 由洛伦兹力折叠的三维微观结构
Isao Shimoyama, Osamu Kano, Hirofumi Miura
We've made a spatial micro-structure by folding at elastic hinges. However, the micro-folding causes the difficulties, e.g. hard access, a time-consuming task, and damage to the structure. In this report, we propose installing micro-actuators on a microstructure to fold it out of a planar structure. The actuator is based on the Lorentz force, which acts on a current in a magnetic field. This actuator can be made simply by using an external magnetic field. The amplitude of the Lorentz force can be controlled by either the current or the magnetic field. Also, the direction of the force can be controlled by the direction of the field.
我们通过弹性铰链的折叠制造了一个空间微观结构。然而,微折叠带来了困难,例如难以进入,耗时的任务,以及破坏结构。在本报告中,我们建议在微观结构上安装微致动器,将其折叠成平面结构。执行器是基于洛伦兹力,它作用于磁场中的电流。这种驱动器可以简单地通过使用外部磁场来制造。洛伦兹力的振幅可以由电流或磁场控制。而且,力的方向可以由电场的方向来控制。
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引用次数: 29
New and extended possibilities of orientation dependent etching in microtechnics 微技术中取向相关蚀刻的新可能性和扩展可能性
B. Hannemann, J. Fruhauf
We will demonstrate that the simple and inexpensive process of orientation dependent wet chemical etching can also be used for the preparation of more complex shapes and elements in microtechnics. In this way it is possible to apply unusual or any mask directions, multi-step etch processes by changing the mask or the etchant between the single steps, modified etchants (like etchants with inorganic or organic additives). The etch rates, the inclinations and the surface qualities of slow etching sidewall faces growing along mask edges in different directions and with different etchants are estimated. With the knowledge of the rates the etching process can be simulated for given mask dimensions and etch conditions.
我们将证明,取向依赖湿化学蚀刻的简单和廉价的过程也可以用于制备更复杂的形状和元素的微技术。通过这种方式,可以应用不寻常的或任何掩膜方向,通过在单步之间改变掩膜或蚀刻剂来进行多步蚀刻工艺,修改蚀刻剂(如添加无机或有机添加剂的蚀刻剂)。对沿掩膜边缘沿不同方向和不同蚀刻剂生长的缓蚀侧壁表面的蚀刻速率、倾斜度和表面质量进行了估计。有了速率的知识,蚀刻过程可以模拟给定的掩膜尺寸和蚀刻条件。
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引用次数: 4
A rotary electrostatic micromotor 1/spl times/8 optical switch 一个旋转静电微电机1/spl次/8光开关
A. A. Yasseen, J. Mitchell, T. Streit, D.A. Smith, M. Mehregany
A 1/spl times/8 rotary electrostatic micromotor optical switch fabricated using deep reactive ion etching technology has been demonstrated. The switches consist of silent-pole micromotors with 1 mm-diameter, 200 /spl mu/m-thick rotors that support either a 200 /spl mu/m or a 500 /spl mu/m-tall, 900 /spl mu/m-wide mirror. After fabrication of the components, switches were assembled and operated for extended periods in room air. Typical switches were actuated at 50 V and found to have a rapid rotation with an average optical switching time between fiber ports of 18.4 ms. Optical testing was performed at 1310 nm in single and multi-mode, and at 850 nm in multi-mode. The optical beam was propagated in free space with minimal divergence through the use of externally-mounted collimating gradient-index (GRIN) lenses. With an aluminum coating, the mirror and external optics exhibited an input to output coupling loss as low as 0.96 dB in multi-mode and 2.32 dB in single-mode. Inter-channel cross talk was less than -45 dB.
利用深反应离子刻蚀技术制备了1/spl倍/8旋转静电微电机光开关。开关由直径为1毫米、转子厚度为200 /spl亩/米的静极微型电机组成,可支持200 /spl亩/米或500 /spl亩/米高、900 /spl亩/米宽的镜面。元件制造完成后,将开关组装起来,并在室内空气中长时间运行。典型的开关在50v下被驱动,并且发现具有快速旋转,光纤端口之间的平均光开关时间为18.4 ms。在1310 nm单模和多模以及850 nm多模下进行光学测试。通过使用外置的准直梯度折射率透镜,光束以最小的散度在自由空间中传播。采用铝涂层后,反射镜和外光学器件的输入输出耦合损耗在多模下低至0.96 dB,在单模下低至2.32 dB。通道间串扰小于-45 dB。
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引用次数: 44
Strain gauge pressure and volume-flow transducers made by thermoplastic molding and membrane transfer 由热塑性成型和膜转移制成的应变式压力和体积流量传感器
J. Martin, W. Bacher, O.F. Hagena, W. Schomburg
Strain gauge pressure and volume-flow transducers have been developed using the techniques of the so-called AMANDA process. It combines injection molding, surface micromachining, and membrane transfer and allows low-cost batch production of microfluidic devices. The strain gauges of the pressure transducer measure the deformation of a thin plate which is a linear function of the differential pressure. For temperature compensation, four strain gauges are arranged to a Wheatstone bridge, operated at constant supply voltage. Different designs cover the pressure range of up to 1 bar, the outer dimensions being 5.5/spl times/4.3/spl times/1.2 mm/sup 3/. A special design with an integrated capillary is used to measure volume flows.
应变计压力和体积流量传感器已经使用所谓的AMANDA工艺技术开发出来。它结合了注射成型,表面微加工和膜转移,并允许低成本批量生产微流体装置。压力传感器的应变片测量薄板的变形,该变形是压差的线性函数。对于温度补偿,四个应变片布置在惠斯通电桥上,在恒定电源电压下工作。不同的设计覆盖压力范围高达1bar,外部尺寸为5.5/spl倍/4.3/spl倍/1.2 mm/sup 3/。集成毛细管的特殊设计用于测量体积流量。
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引用次数: 27
Microfabrication and parallel operation of 5/spl times/5 2D AFM cantilever arrays for data storage and imaging 用于数据存储和成像的5/spl次/5二维AFM悬臂阵列的微加工和并行操作
M. Lutwyche, C. Andreoli, G. Binnig, J. Brugger, U. Drechsler, W. Haeberle, H. Rohrer, H. Rothuizen, P. Vettiger
In this paper we report on the microfabrication of a 5/spl times/5 2D cantilever array and its successful application to parallel imaging. The 5/spl times/5 array with integrated force sensing and tip heating has been fabricated using a recently developed, all dry silicon backside etching process. The levers on the array have integrated piezoresistive sensing. The array is scanned in x and y directions using voice coil actuators. Three additional voice coil z actuators are used in a triangular arrangement to approach the sample with the array chip. The system is thus leveled in the same way as an air table. We report details of the array fabrication, the x-y scanning and approach system as well as images taken with the system.
本文报道了5/spl倍/5二维悬臂阵列的微加工及其在平行成像中的成功应用。集成力传感和尖端加热的5/spl倍/5阵列采用最近开发的全干硅背面蚀刻工艺制造。阵列上的杠杆集成了压阻式传感。使用音圈驱动器在x和y方向上扫描阵列。三个额外的音圈z形致动器以三角形排列使用阵列芯片接近样品。因此,该系统以与空气表相同的方式被调平。我们报告了阵列制造的细节,x-y扫描和接近系统以及用该系统拍摄的图像。
{"title":"Microfabrication and parallel operation of 5/spl times/5 2D AFM cantilever arrays for data storage and imaging","authors":"M. Lutwyche, C. Andreoli, G. Binnig, J. Brugger, U. Drechsler, W. Haeberle, H. Rohrer, H. Rothuizen, P. Vettiger","doi":"10.1109/MEMSYS.1998.659720","DOIUrl":"https://doi.org/10.1109/MEMSYS.1998.659720","url":null,"abstract":"In this paper we report on the microfabrication of a 5/spl times/5 2D cantilever array and its successful application to parallel imaging. The 5/spl times/5 array with integrated force sensing and tip heating has been fabricated using a recently developed, all dry silicon backside etching process. The levers on the array have integrated piezoresistive sensing. The array is scanned in x and y directions using voice coil actuators. Three additional voice coil z actuators are used in a triangular arrangement to approach the sample with the array chip. The system is thus leveled in the same way as an air table. We report details of the array fabrication, the x-y scanning and approach system as well as images taken with the system.","PeriodicalId":340972,"journal":{"name":"Proceedings MEMS 98. IEEE. Eleventh Annual International Workshop on Micro Electro Mechanical Systems. An Investigation of Micro Structures, Sensors, Actuators, Machines and Systems (Cat. No.98CH36176","volume":"235 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1998-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114277908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 32
期刊
Proceedings MEMS 98. IEEE. Eleventh Annual International Workshop on Micro Electro Mechanical Systems. An Investigation of Micro Structures, Sensors, Actuators, Machines and Systems (Cat. No.98CH36176
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