首页 > 最新文献

2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)最新文献

英文 中文
A portable hardware implementation for temporal laser speckle imaging 时间激光散斑成像的便携式硬件实现
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679636
A. Rege, B. Tyler, M. J. Brooke, K. Murari
We present a memory-optimized, portable hardware implementation for temporal laser speckle imaging (tLSI) consisting of a complementary metal oxide semiconductor (CMOS) image sensor, a field programmable gate array (FPGA) processor and a microSD card for storage. The system is compared to a typical benchtop setup consisting of a charge coupled device (CCD) based image sensor and a computer for imaging rat brain vasculature. The hardware implementation enables faster operation, reduced data bandwidth, lower power consumption, smaller footprint and comparable performance in terms of contrast to noise ratio and flow-fidelity. We expect these advantages to enable portable, point-of-care diagnostic imaging devices for high-resolution, high-contrast measurement of haemodynamic parameters.
我们提出了一种用于时间激光散斑成像(tLSI)的存储优化的便携式硬件实现,该硬件由互补金属氧化物半导体(CMOS)图像传感器、现场可编程门阵列(FPGA)处理器和用于存储的microSD卡组成。该系统与典型的台式装置相比较,该装置由基于电荷耦合器件(CCD)的图像传感器和用于成像大鼠脑血管系统的计算机组成。硬件实现实现了更快的操作、更少的数据带宽、更低的功耗、更小的占地面积,并且在噪声比和流量保真度方面具有可比的性能。我们期望这些优势能够实现便携式、即时诊断成像设备,用于高分辨率、高对比度的血流动力学参数测量。
{"title":"A portable hardware implementation for temporal laser speckle imaging","authors":"A. Rege, B. Tyler, M. J. Brooke, K. Murari","doi":"10.1109/BioCAS.2013.6679636","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679636","url":null,"abstract":"We present a memory-optimized, portable hardware implementation for temporal laser speckle imaging (tLSI) consisting of a complementary metal oxide semiconductor (CMOS) image sensor, a field programmable gate array (FPGA) processor and a microSD card for storage. The system is compared to a typical benchtop setup consisting of a charge coupled device (CCD) based image sensor and a computer for imaging rat brain vasculature. The hardware implementation enables faster operation, reduced data bandwidth, lower power consumption, smaller footprint and comparable performance in terms of contrast to noise ratio and flow-fidelity. We expect these advantages to enable portable, point-of-care diagnostic imaging devices for high-resolution, high-contrast measurement of haemodynamic parameters.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114309659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Automatic detection of sleep spindles using Teager energy and spectral edge frequency 利用蒂格尔能量和频谱边缘频率自动检测睡眠纺锤体
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679689
S. Imtiaz, Siavash Saremi-Yarahmadi, E. Rodríguez-Villegas
Sleep spindles are the hallmark of N2 stage of sleep. They are transient waveforms observed on sleep electroencephalogram and their identification is required for sleep staging. Due to the large number of sleep spindles appearing on an overnight sleep EEG, automating the detection of sleep spindles would be desirable, not only to save specialist time but also for fully automated sleep staging systems. A simple algorithm for automatic sleep spindle detection is presented in this paper using only one channel of EEG input. This algorithm uses Teager energy and spectral edge frequency to mark sleep spindles and results in a sensitivity of 80% and specificity of about 98%. It is also shown that more than 91% of spindles detected by the algorithm were in N2 and N3 stages combined.
睡眠纺锤波是睡眠第二阶段的标志。它们是在睡眠脑电图上观察到的短暂波形,对其进行识别是睡眠分期的必要条件。由于大量的睡眠纺锤波出现在夜间睡眠脑电图,自动检测睡眠纺锤波将是可取的,不仅节省专家的时间,而且完全自动化的睡眠分期系统。本文提出了一种基于单通道脑电输入的睡眠纺锤体自动检测算法。该算法利用Teager能量和谱边缘频率对睡眠纺锤波进行标记,灵敏度为80%,特异性约为98%。结果表明,该算法检测到的纺锤体中,超过91%的纺锤体处于N2和N3阶段。
{"title":"Automatic detection of sleep spindles using Teager energy and spectral edge frequency","authors":"S. Imtiaz, Siavash Saremi-Yarahmadi, E. Rodríguez-Villegas","doi":"10.1109/BioCAS.2013.6679689","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679689","url":null,"abstract":"Sleep spindles are the hallmark of N2 stage of sleep. They are transient waveforms observed on sleep electroencephalogram and their identification is required for sleep staging. Due to the large number of sleep spindles appearing on an overnight sleep EEG, automating the detection of sleep spindles would be desirable, not only to save specialist time but also for fully automated sleep staging systems. A simple algorithm for automatic sleep spindle detection is presented in this paper using only one channel of EEG input. This algorithm uses Teager energy and spectral edge frequency to mark sleep spindles and results in a sensitivity of 80% and specificity of about 98%. It is also shown that more than 91% of spindles detected by the algorithm were in N2 and N3 stages combined.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114332129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Framework for evaluating EEG signal quality of dry electrode recordings 干电极记录的脑电信号质量评价框架
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679670
Alexandra-Maria Tăuțan, W. Serdijn, V. Mihajlović, B. Grundlehner, J. Penders
Dry electrodes provide the possibility of moving EEG usage from the research and clinical environment to real life applications. Having a framework for evaluating the performance of dry electrodes would facilitate this process and help EEG system developers to test their designs. This paper describes an evaluation method for dry electrode EEG recordings. The framework includes a setup for synchronous recordings with a parallel dry and gel electrode montage procedure. Several protocols are implemented to evaluate both the time and frequency content of the signal and to compute the setup and settling time. Signal quality was evaluated using signal correlations, SNR and P300 component characteristics. The preliminary data analysis and results show that a comparison between gel and dry electrodes is possible but improvements need to be made to the current evaluation framework.
干电极提供了将脑电图从研究和临床环境转移到现实生活应用的可能性。有一个评估干电极性能的框架将促进这一过程,并帮助脑电图系统开发人员测试他们的设计。本文介绍了一种干电极脑电记录的评价方法。该框架包括用于同步记录的设置与平行干燥和凝胶电极蒙太奇程序。实现了几种协议来评估信号的时间和频率内容,并计算设置和稳定时间。使用信号相关性、信噪比和P300分量特性来评估信号质量。初步的数据分析和结果表明,凝胶电极和干电极之间的比较是可能的,但需要对当前的评估框架进行改进。
{"title":"Framework for evaluating EEG signal quality of dry electrode recordings","authors":"Alexandra-Maria Tăuțan, W. Serdijn, V. Mihajlović, B. Grundlehner, J. Penders","doi":"10.1109/BioCAS.2013.6679670","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679670","url":null,"abstract":"Dry electrodes provide the possibility of moving EEG usage from the research and clinical environment to real life applications. Having a framework for evaluating the performance of dry electrodes would facilitate this process and help EEG system developers to test their designs. This paper describes an evaluation method for dry electrode EEG recordings. The framework includes a setup for synchronous recordings with a parallel dry and gel electrode montage procedure. Several protocols are implemented to evaluate both the time and frequency content of the signal and to compute the setup and settling time. Signal quality was evaluated using signal correlations, SNR and P300 component characteristics. The preliminary data analysis and results show that a comparison between gel and dry electrodes is possible but improvements need to be made to the current evaluation framework.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"155 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132492235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 22
Low-power low-noise ECG acquisition system with dsp for heart disease identification 基于dsp的心脏病识别低功耗低噪声心电采集系统
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679630
Bo-Yu Shiu, Shuohan Wang, Y. Chu, T. Tsai
In this paper, we implemented a low-power low-noise ECG acquisition system for heart disease identifications. The ECG signal is acquired with an analog front-end circuit, and the offset and baseline drift is eliminated at the same time. We also implemented a digital signal processing (DSP) unit to effectively remove EMG interferences. Interception of ST segment is proposed to achieve the identification of heart diseases. The ECG front-end chip has been designed and fabricated by using a TSMC 90nm CMOS technology, the total power consumption was measured at 40.3μW. DSP algorithms are carried out in the FPGA. Experimental results show that the sensitivity and specificity of ST segment classification after EMG elimination is 96.6% and 93.1%, respectively.
在本文中,我们实现了一种用于心脏病识别的低功耗低噪声心电采集系统。采用模拟前端电路采集心电信号,同时消除了偏移和基线漂移。我们还实现了一个数字信号处理(DSP)单元来有效地去除肌电图干扰。提出ST段阻断,实现心脏疾病的识别。采用台积电90nm CMOS工艺设计制作了心电前端芯片,总功耗为40.3μW。DSP算法在FPGA中实现。实验结果表明,消除肌电图后ST段分类的灵敏度和特异性分别为96.6%和93.1%。
{"title":"Low-power low-noise ECG acquisition system with dsp for heart disease identification","authors":"Bo-Yu Shiu, Shuohan Wang, Y. Chu, T. Tsai","doi":"10.1109/BioCAS.2013.6679630","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679630","url":null,"abstract":"In this paper, we implemented a low-power low-noise ECG acquisition system for heart disease identifications. The ECG signal is acquired with an analog front-end circuit, and the offset and baseline drift is eliminated at the same time. We also implemented a digital signal processing (DSP) unit to effectively remove EMG interferences. Interception of ST segment is proposed to achieve the identification of heart diseases. The ECG front-end chip has been designed and fabricated by using a TSMC 90nm CMOS technology, the total power consumption was measured at 40.3μW. DSP algorithms are carried out in the FPGA. Experimental results show that the sensitivity and specificity of ST segment classification after EMG elimination is 96.6% and 93.1%, respectively.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132811220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Single-wire RF transmission lines for implanted devices 用于植入设备的单线射频传输线
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679679
J. Besnoff, M. Reynolds
We consider the use of insulated single wires as transmission lines to carry 100 MHz - 3 GHz radio frequency (RF) signals among devices implanted in biological tissue. In contrast to near-field magnetically coupled links, the use of transmission lines to carry RF signals results in higher efficiency for a given implant package size once the antenna is included, albeit with the disadvantage of tissue displacement along the path of the wire. We present a theory based on the work of Goubau and Rao that describes the transmission line loss of a single insulated wire in a lossy dielectric medium. We experimentally verify the characteristic impedance and insertion loss of transmission lines formed by thin wires insulated with Teflon fluorinated ethylene propylene (FEP). We consider media including 0.91% saline (a homogeneous tissue proxy), muscle tissue, and brain tissue, and present a launcher design based on a dielectric loaded coaxial sleeve. For example, in the saline proxy, a single FEP-insulated conductor of only 0.127 mm diameter presents a measured return loss of 10 dB in a 50Ω system, with a measured insertion loss of only 1 dB/cm at 1 GHz.
我们考虑使用绝缘单线作为传输线,在植入生物组织的设备之间携带100 MHz - 3 GHz射频(RF)信号。与近场磁耦合链路相比,使用传输线来携带射频信号,一旦包含天线,对于给定的植入物封装尺寸具有更高的效率,尽管缺点是组织沿着导线的路径移位。我们在Goubau和Rao的工作基础上提出了一个理论,描述了在有耗介质中单根绝缘导线的传输线损耗。实验验证了用特氟隆氟化乙丙烯(FEP)绝缘的细导线构成的传输线的特性阻抗和插入损耗。我们考虑了包括0.91%生理盐水(一种均质组织代理)、肌肉组织和脑组织在内的介质,并提出了一种基于介质加载同轴套管的发射器设计。例如,在盐水代理中,在50Ω系统中,单个直径仅为0.127 mm的fep绝缘导体的测量回波损耗为10 dB,在1 GHz时测量的插入损耗仅为1 dB/cm。
{"title":"Single-wire RF transmission lines for implanted devices","authors":"J. Besnoff, M. Reynolds","doi":"10.1109/BioCAS.2013.6679679","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679679","url":null,"abstract":"We consider the use of insulated single wires as transmission lines to carry 100 MHz - 3 GHz radio frequency (RF) signals among devices implanted in biological tissue. In contrast to near-field magnetically coupled links, the use of transmission lines to carry RF signals results in higher efficiency for a given implant package size once the antenna is included, albeit with the disadvantage of tissue displacement along the path of the wire. We present a theory based on the work of Goubau and Rao that describes the transmission line loss of a single insulated wire in a lossy dielectric medium. We experimentally verify the characteristic impedance and insertion loss of transmission lines formed by thin wires insulated with Teflon fluorinated ethylene propylene (FEP). We consider media including 0.91% saline (a homogeneous tissue proxy), muscle tissue, and brain tissue, and present a launcher design based on a dielectric loaded coaxial sleeve. For example, in the saline proxy, a single FEP-insulated conductor of only 0.127 mm diameter presents a measured return loss of 10 dB in a 50Ω system, with a measured insertion loss of only 1 dB/cm at 1 GHz.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134002856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Design optimization of the optical receiver in transcutaneous telemetric links 经皮遥测链路中光学接收器的设计优化
Pub Date : 2013-12-12 DOI: 10.1109/BIOCAS.2013.6679710
Tianyi Liu, J. Anders, M. Ortmanns
This paper presents a design methodology for an optimization of the optical receiver in a neural recording system. In the transcutaneous optical telemetric link (TOTL) system, light/tissue interaction produces significant scattering of the transmitted photons. Therefore, in order to increase the transmission efficiency, it is in principle advantageous to use a photodiode with a larger size to collect more scattered photons. The photodiode size, however, is limited by the bandwidth requirement. In this paper, we derive a mathematical expression of the maximum photodiode size in the presence of constraints imposed by its bias voltage and the receiver bandwidth. A numerical example using real-world TOTL system parameters is given to demonstrate the design methodology. The trade off between transmission efficiency, noise and inter-symbol interference (ISI) in terms of the 3-dB bandwidth of the receiver is investigated. To this end, receivers with bandwidth about 4/3, 3/3, 2/3 and 1/3 of the data rate are compared with respect to the sensitivity. It was found that the receiver bandwidth of 2/3 of the data rate achieves the highest sensitivity for thin tissue (2 mm) and that a receiver bandwidth of 1/3 of the data rate is preferable for thicker tissues (5 and 8 mm).
本文提出了一种优化神经记录系统光接收机的设计方法。在经皮光学遥测链路(TOTL)系统中,光/组织相互作用产生传输光子的显著散射。因此,为了提高传输效率,原则上使用尺寸更大的光电二极管来收集更多的散射光子是有利的。然而,光电二极管的尺寸受到带宽要求的限制。在本文中,我们推导了在其偏置电压和接收器带宽约束下光电二极管最大尺寸的数学表达式。以实际total系统参数为例,说明了设计方法。研究了传输效率、噪声和码间干扰(ISI)在接收机3db带宽方面的权衡。为此,对带宽约为数据速率的4/ 3,3 / 3,2 /3和1/3的接收机进行灵敏度比较。研究发现,对于薄组织(2mm),接收带宽为数据速率的2/3可获得最高灵敏度,而对于厚组织(5和8mm),接收带宽为数据速率的1/3更可取。
{"title":"Design optimization of the optical receiver in transcutaneous telemetric links","authors":"Tianyi Liu, J. Anders, M. Ortmanns","doi":"10.1109/BIOCAS.2013.6679710","DOIUrl":"https://doi.org/10.1109/BIOCAS.2013.6679710","url":null,"abstract":"This paper presents a design methodology for an optimization of the optical receiver in a neural recording system. In the transcutaneous optical telemetric link (TOTL) system, light/tissue interaction produces significant scattering of the transmitted photons. Therefore, in order to increase the transmission efficiency, it is in principle advantageous to use a photodiode with a larger size to collect more scattered photons. The photodiode size, however, is limited by the bandwidth requirement. In this paper, we derive a mathematical expression of the maximum photodiode size in the presence of constraints imposed by its bias voltage and the receiver bandwidth. A numerical example using real-world TOTL system parameters is given to demonstrate the design methodology. The trade off between transmission efficiency, noise and inter-symbol interference (ISI) in terms of the 3-dB bandwidth of the receiver is investigated. To this end, receivers with bandwidth about 4/3, 3/3, 2/3 and 1/3 of the data rate are compared with respect to the sensitivity. It was found that the receiver bandwidth of 2/3 of the data rate achieves the highest sensitivity for thin tissue (2 mm) and that a receiver bandwidth of 1/3 of the data rate is preferable for thicker tissues (5 and 8 mm).","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"47 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134344950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A training system for the MyoBock hand in a virtual reality environment MyoBock手在虚拟现实环境中的训练系统
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679640
Go Nakamura, T. Shibanoki, K. Shima, Y. Kurita, Masaki Hasegawa, A. Otsuka, Y. Honda, T. Chin, T. Tsuji
This paper proposes a novel EMG-based MyoBock training system that consistently provides a variety of functions ranging from EMG signal control training to task training. Using the proposed training sytem, a trainee controls a virtual hand (VH) in a 3D virtual reality (VR) environment using EMG signals and position/posture information recorded from the trainee. The trainee can also perform tasks such as holding and moving virtual objects using the system. In the experiments of this study, virtual task training developed with reference to the Box and Block Test (BBT) used to evaluate myoelectric prostheses was conducted with two healthy subjects, who repeatedly performed 10 one-minute tasks involving grasping a ball in one box and transporting it to another. The BBT experiments were also conducted in a real environment before and after the virtual training, with results showing an improvement in the number of tasks successfully completed. It was therefore confirmed that the proposed system could be used for myoelectric prosthesis control training.
本文提出了一种基于肌电图的MyoBock训练系统,该系统能够持续提供从肌电信号控制训练到任务训练的多种功能。使用所提出的训练系统,受训者在3D虚拟现实(VR)环境中使用肌电信号和记录的位置/姿势信息控制虚拟手(VH)。受训者还可以使用该系统执行诸如持有和移动虚拟物体之类的任务。在本研究的实验中,参照评估肌电假体的盒子和块测试(BBT)开发的虚拟任务训练在两名健康受试者中进行,他们重复执行10个一分钟的任务,包括抓住一个盒子里的球并将其运送到另一个盒子里。在虚拟训练前后,在真实环境中也进行了BBT实验,结果显示成功完成任务的数量有所增加。因此,该系统可用于肌电假肢控制训练。
{"title":"A training system for the MyoBock hand in a virtual reality environment","authors":"Go Nakamura, T. Shibanoki, K. Shima, Y. Kurita, Masaki Hasegawa, A. Otsuka, Y. Honda, T. Chin, T. Tsuji","doi":"10.1109/BioCAS.2013.6679640","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679640","url":null,"abstract":"This paper proposes a novel EMG-based MyoBock training system that consistently provides a variety of functions ranging from EMG signal control training to task training. Using the proposed training sytem, a trainee controls a virtual hand (VH) in a 3D virtual reality (VR) environment using EMG signals and position/posture information recorded from the trainee. The trainee can also perform tasks such as holding and moving virtual objects using the system. In the experiments of this study, virtual task training developed with reference to the Box and Block Test (BBT) used to evaluate myoelectric prostheses was conducted with two healthy subjects, who repeatedly performed 10 one-minute tasks involving grasping a ball in one box and transporting it to another. The BBT experiments were also conducted in a real environment before and after the virtual training, with results showing an improvement in the number of tasks successfully completed. It was therefore confirmed that the proposed system could be used for myoelectric prosthesis control training.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132042536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Joint analog-to-information conversion of heterogeneous biosignals 异质生物信号的联合模拟-信息转换
Pub Date : 2013-12-12 DOI: 10.1109/BioCAS.2013.6679663
V. Cambareri, Mauro Mangia, R. Rovatti, G. Setti
In this work, we propose an analog-to-information conversion based sensing protocol for the joint acquisition of signals in a typical body sensor network composed of different kinds of sensing devices. The proposed system is based on the compressive sensing paradigm, and jointly encodes sparse and non-sparse signals with an advantage in terms of required transmission bits and achieved signal-to-noise ratio with respect to the standard case of disjoint signal acquisition. A theoretical analysis is supported by some practical examples which show how the proposed system is able to outperform traditional approaches.
在这项工作中,我们提出了一种基于模拟-信息转换的传感协议,用于在由不同类型的传感设备组成的典型身体传感器网络中联合采集信号。该系统基于压缩感知范式,对稀疏和非稀疏信号进行联合编码,在所需传输比特方面具有优势,并且相对于不相交信号采集的标准情况实现了信噪比。理论分析得到了一些实际例子的支持,表明所提出的系统如何能够优于传统方法。
{"title":"Joint analog-to-information conversion of heterogeneous biosignals","authors":"V. Cambareri, Mauro Mangia, R. Rovatti, G. Setti","doi":"10.1109/BioCAS.2013.6679663","DOIUrl":"https://doi.org/10.1109/BioCAS.2013.6679663","url":null,"abstract":"In this work, we propose an analog-to-information conversion based sensing protocol for the joint acquisition of signals in a typical body sensor network composed of different kinds of sensing devices. The proposed system is based on the compressive sensing paradigm, and jointly encodes sparse and non-sparse signals with an advantage in terms of required transmission bits and achieved signal-to-noise ratio with respect to the standard case of disjoint signal acquisition. A theoretical analysis is supported by some practical examples which show how the proposed system is able to outperform traditional approaches.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132136621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Nanogap-based enzymatic-free electrochemical detection of glucose 基于纳米间隙的葡萄糖无酶电化学检测
Pub Date : 2013-12-12 DOI: 10.1109/BIOCAS.2013.6679656
Ismael Rattalino, P. Ros, I. Taurino, F. Cortés-Salazar, G. Piccinini, D. Demarchi, G. Micheli, S. Carrara
Although non-enzymatic glucose sensors have demonstrated better stability and reproducibility with respect to enzymatic ones, so far they have been inappropriate for most applications, since they require alkaline conditions to achieve the necessary sensitivity. In this work, we propose a gold nanogap-based non-enzymatic sensor to localize the generation of alkaline conditions inside the gap, thus preserving the overall pH in the media during glucose detection. The working principle is based on an electrochemical bi-potentiostatic measurement, where an alkaline aqueous condition is locally generated at one side of nanogap, while glucose detection is performed at the counterpart. To this purpose, a nanogap array platform was fabricated by means of standard lithography and controlled electromigration. Mono-potentiostatic electrochemical detection of ascorbic acid was successfully performed to preliminary test the platform prior to measuring glucose in bi-potentiostatic mode. Cyclic voltammetries reveal that two oxidation peaks are sensitive to glucose concentration, making nanogap glucose detection possible in principle. This promising proof of concept could be innovative in bio-applications with implantable devices or direct monitoring of cell culture, where neutral pH in contact with living tissue is required. Further geometrical improvements of the system to increase the durability of the sensor are currently still in progress, and are briefly discussed in the final part of the paper.
尽管非酶葡萄糖传感器已经证明了比酶葡萄糖传感器更好的稳定性和可重复性,但到目前为止,它们还不适合大多数应用,因为它们需要碱性条件才能达到必要的灵敏度。在这项工作中,我们提出了一种基于金纳米间隙的非酶传感器,用于定位间隙内碱性条件的产生,从而在葡萄糖检测过程中保持培养基中的整体pH。工作原理是基于电化学双恒电位测量,其中在纳米间隙的一侧局部产生碱性水条件,而在对应的位置进行葡萄糖检测。为此,采用标准光刻和可控电迁移的方法制备了纳米隙阵列平台。在双恒电位模式下测定葡萄糖之前,成功地进行了抗坏血酸的单恒电位电化学检测,对平台进行了初步测试。循环伏安法显示两个氧化峰对葡萄糖浓度敏感,使纳米间隙葡萄糖检测在原则上成为可能。这一有希望的概念证明在生物应用中具有创新性,可植入设备或直接监测细胞培养,其中需要与活组织接触的中性pH值。进一步的几何改进系统,以增加传感器的耐用性目前仍在进行中,并在论文的最后部分简要讨论。
{"title":"Nanogap-based enzymatic-free electrochemical detection of glucose","authors":"Ismael Rattalino, P. Ros, I. Taurino, F. Cortés-Salazar, G. Piccinini, D. Demarchi, G. Micheli, S. Carrara","doi":"10.1109/BIOCAS.2013.6679656","DOIUrl":"https://doi.org/10.1109/BIOCAS.2013.6679656","url":null,"abstract":"Although non-enzymatic glucose sensors have demonstrated better stability and reproducibility with respect to enzymatic ones, so far they have been inappropriate for most applications, since they require alkaline conditions to achieve the necessary sensitivity. In this work, we propose a gold nanogap-based non-enzymatic sensor to localize the generation of alkaline conditions inside the gap, thus preserving the overall pH in the media during glucose detection. The working principle is based on an electrochemical bi-potentiostatic measurement, where an alkaline aqueous condition is locally generated at one side of nanogap, while glucose detection is performed at the counterpart. To this purpose, a nanogap array platform was fabricated by means of standard lithography and controlled electromigration. Mono-potentiostatic electrochemical detection of ascorbic acid was successfully performed to preliminary test the platform prior to measuring glucose in bi-potentiostatic mode. Cyclic voltammetries reveal that two oxidation peaks are sensitive to glucose concentration, making nanogap glucose detection possible in principle. This promising proof of concept could be innovative in bio-applications with implantable devices or direct monitoring of cell culture, where neutral pH in contact with living tissue is required. Further geometrical improvements of the system to increase the durability of the sensor are currently still in progress, and are briefly discussed in the final part of the paper.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"55 34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114509936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computation using mismatch: Neuromorphic extreme learning machines 不匹配计算:神经形态极限学习机
Pub Date : 2013-12-12 DOI: 10.1109/BIOCAS.2013.6679697
Enyi Yao, Shaista Hussain, A. Basu, G. Huang
In this paper, we describe a low power neuromorphic machine learner that utilizes device mismatch prevalent in today's VLSI processes to perform a significant part of the computation while a digital back end enables precision in the final output. The particular machine learning algorithm we use is extreme learning machine (ELM). Mismatch in silicon spiking neurons and synapses are used to perform the vector-matrix multiplication (VMM) that forms the first stage of this classifier and is the most computationally intensive. System simulations are presented to evaluate the dependence of performance (in a classification and a regression task) on analog and digital parameters like weight resolution, maximum spike frequency etc. SPICE simulations show that the proposed implementation is ≈ 92X more energy efficient as opposed to custom digital implementations for a classification task with 100 dimensional inputs. Measurement results for a regression task from a field programmable analog array (FPAA) fabricated in 0.35μm CMOS are presented as a proof of concept.
在本文中,我们描述了一种低功耗神经形态机器学习,它利用当今VLSI工艺中普遍存在的器件不匹配来执行计算的重要部分,而数字后端可以实现最终输出的精度。我们使用的特殊机器学习算法是极限学习机(ELM)。硅尖峰神经元和突触的不匹配用于执行向量矩阵乘法(VMM),这是该分类器的第一阶段,也是计算最密集的阶段。提出了系统仿真来评估性能(在分类和回归任务中)对模拟和数字参数(如权重分辨率,最大尖峰频率等)的依赖性。SPICE仿真表明,对于具有100维输入的分类任务,与自定义数字实现相比,所提出的实现节能约92倍。在0.35μm CMOS中制作的现场可编程模拟阵列(FPAA)的回归任务的测量结果作为概念验证。
{"title":"Computation using mismatch: Neuromorphic extreme learning machines","authors":"Enyi Yao, Shaista Hussain, A. Basu, G. Huang","doi":"10.1109/BIOCAS.2013.6679697","DOIUrl":"https://doi.org/10.1109/BIOCAS.2013.6679697","url":null,"abstract":"In this paper, we describe a low power neuromorphic machine learner that utilizes device mismatch prevalent in today's VLSI processes to perform a significant part of the computation while a digital back end enables precision in the final output. The particular machine learning algorithm we use is extreme learning machine (ELM). Mismatch in silicon spiking neurons and synapses are used to perform the vector-matrix multiplication (VMM) that forms the first stage of this classifier and is the most computationally intensive. System simulations are presented to evaluate the dependence of performance (in a classification and a regression task) on analog and digital parameters like weight resolution, maximum spike frequency etc. SPICE simulations show that the proposed implementation is ≈ 92X more energy efficient as opposed to custom digital implementations for a classification task with 100 dimensional inputs. Measurement results for a regression task from a field programmable analog array (FPAA) fabricated in 0.35μm CMOS are presented as a proof of concept.","PeriodicalId":344317,"journal":{"name":"2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125969265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
期刊
2013 IEEE Biomedical Circuits and Systems Conference (BioCAS)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1