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Quantitative measurement of sugar concentration using in house fabricated microgap biosensor 自制微间隙生物传感器对糖浓度的定量测定
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706471
B. S. Rao, M. Nurfaiz, U. Hashim
Sugar is carbohydrate sweet-flavoured substance that composed of carbon, oxygen and hydrogen. It is an important component to provide sweet taste in food. Besides, it also provides immediate energy to complete daily routine life. However, uncontrolled amount of sugar can lead to serious health complications and diseases such as Hypoglycemia (low sugar in blood), syndrome X, diabetes and heart disease. Low amount of sugar in bloodstream may cause nausea and dizziness. Besides that, it also can be used as sensor to detect the amount of sugar in beverages. Here, sugar is used as a reference measurement to test the functionality of the device before testing it in real life using glucose samples. In future, real urine samples will be used to measure concentration of glucose in diabetic patients. In this paper, sugar concentration measurement based on microgap biosensor is fabricated by using conventional photolithography process. Silicon was used as the substrate material and followed by layers of Silicon dioxide (SiO2), Polysilicon, Titanium (Ti) and Gold (Au). Chrome mask were used to transfer pattern of microgap and contact pads onto the silicon substrate. The device design has been optimised to achieve few performance factors that includes accuracy, sensitivity, response time and fabrication cost. A number of sugar concentrations were prepared by diluting it with DI water for measurement process by electrical characterization. In this work, studies and analysis were conducted based on different concentration of sugar on constant sized microgap and based on different size of microgap structure on constant sugar concentration. As the result, the experiment has been successfully yielded a high sensitive microgap sensor and the lowest detected sugar concentration sample is 0.0245gml-1. This method of biosensing provides a very simple and promising detection technique for any kind of biomolecules that includes proteins, DNA, enzymes, antibody and antigen.
糖是由碳、氧和氢组成的碳水化合物甜味物质。它是食物中提供甜味的重要成分。此外,它还为完成日常生活提供了直接的能量。然而,不受控制的糖量会导致严重的健康并发症和疾病,如低血糖症(低血糖)、X综合征、糖尿病和心脏病。血液中含糖量过低会引起恶心和头晕。此外,它还可以作为传感器来检测饮料中的含糖量。在这里,糖被用作参考测量来测试设备的功能,然后在现实生活中使用葡萄糖样本进行测试。未来,真实的尿液样本将被用于测量糖尿病患者的葡萄糖浓度。本文采用传统光刻工艺制备了基于微间隙生物传感器的糖浓度测量方法。采用硅作为衬底材料,然后是二氧化硅(SiO2)、多晶硅、钛(Ti)和金(Au)层。采用镀铬掩模将微隙和接触片的图案转移到硅衬底上。该器件设计经过优化,实现了精度、灵敏度、响应时间和制造成本等少数性能因素。用去离子水稀释制备了若干糖浓度,用于电表征的测量过程。在本工作中,分别对不同糖浓度对定尺寸微间隙的影响和不同糖浓度对定尺寸微间隙结构的影响进行了研究和分析。实验成功制备了高灵敏度的微间隙传感器,最低检测糖浓度样品为0.0245gml-1。这种生物传感方法为包括蛋白质、DNA、酶、抗体和抗原在内的任何种类的生物分子提供了一种非常简单和有前途的检测技术。
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引用次数: 2
Numerical study of side gate junction-less transistor in on state 边栅无结晶体管导通状态的数值研究
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706575
A. Dehzangi, F. Larki, B. Majlis, M. Hamidon, M. Navasery, E. Gharibshahi, N. Khalilzadeh, M. Vakilian, E. Saion
Side gate p-type Junctionless Silicon transistor is fabricated by AFM nanolithography on low-doped (105 cm-3) SOI wafer. In this work, the simulation characteristic of the device using TCAD Sentaurus in on state will be studied. The results show that the device is the pinch off transistor, works in on state for zero gate voltage in depletion mode. Negative gate voltage drives the device into on state, but unable to make significant effect on drain current as accmulation mode. Simulation results for valence band energy, electric field and hole density are investigated along the active regions. The influence of the electric field due to the applied voltages of VDS and VG on charge distribution is much more when the device operates at the saturation region. The hole quasi-Fermi level has a positive slope showing the current flows from source to drain.
采用AFM纳米光刻技术,在低掺杂(105 cm-3) SOI晶圆上制备了侧栅p型无结硅晶体管。在本工作中,将研究使用TCAD Sentaurus在开启状态下对器件的仿真特性。结果表明,该器件为掐断型晶体管,在耗尽模式下工作在零栅极电压导通状态。负栅极电压驱动器件进入导通状态,但作为累加方式对漏极电流不能产生显著影响。研究了活性区的价带能、电场和空穴密度的模拟结果。当器件工作在饱和区时,由VDS和VG外加电压引起的电场对电荷分布的影响更大。孔准费米能级具有正斜率,表明电流从源极流向漏极。
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引用次数: 0
Memristor based delay element using current starved inverter 基于忆阻器的电流饥渴型逆变器延时元件
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706478
Siti Musliha Ajmal Binti Mokhtar, W. Abdullah
This paper will first review on some applications of newly found passive element, the memristor. Utilizing the beneficial characteristic of memristor where it can remember its last state, more and more improvements on today electronic designs has been proposed. However, it is crucial to observe the behavior of memristor model before applying into circuits, especially when the memristor is coupled with other devices. In this paper, LTspice memristor model is used to simulate memristor behavior and applied to the basic delay element circuit. The circuit used a tristate inverter as the delay element. It controls the current flowing to the parasitic capacitor, thus controlling the delay. The compatibility of memristor with the delay element is also in consideration to ensure the functionality of the circuits. At the end, a basic delay element using inverter and memristor is presented. This paper is divided into 4 sections, including the introduction where few examples of memristor applications are explained. It follows by next section where the inverter delay characteristic is narrated. Section 3 is about a mathematical model of memristor that been used to provide a specific memristor resistance in order to get certain delay value during simulation. Using LT spice, a memristor based delay circuit design is then proposed and the delay is observed by circuit simulation. In conclusion, the calculated R and delay value is then compared to the simulation result in order to verify circuit functionality.
本文首先综述了新发现的无源元件忆阻器的一些应用。利用忆阻器能记住其最后状态的有利特性,对当今的电子设计提出了越来越多的改进。然而,在应用到电路中,特别是当忆阻器与其他器件耦合时,观察忆阻器模型的行为是至关重要的。本文采用LTspice忆阻器模型来模拟忆阻器的行为,并将其应用于基本延迟元件电路。该电路采用三态逆变器作为延时元件。它控制流向寄生电容的电流,从而控制延迟。为了保证电路的功能,还考虑了忆阻器与延迟元件的兼容性。最后,提出了一种基于逆变器和忆阻器的基本延迟元件。本文分为4个部分,包括引言部分,其中解释了几个忆阻器应用的例子。接下来是下一节,其中逆变器的延迟特性是叙述。第3节是关于忆阻器的数学模型,在仿真过程中提供特定的忆阻电阻以获得一定的延迟值。在此基础上,提出了一种基于忆阻器的延迟电路设计,并通过电路仿真观察了延迟。最后,将计算的R值和延迟值与仿真结果进行比较,以验证电路的功能。
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引用次数: 5
Investigating the annealing effect on the conventional growth of ZnO nanorod through electrical characterization 通过电学表征研究了退火对ZnO纳米棒常规生长的影响
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706536
R. Prasad, U. Hashim, K. L. Foo, M. Shafiq
Zinc oxide nanorods was synthesized by using hydrothermal growth due to simplicity and involve low temperature processing that is 930C. Low temperature processing is very essential for ZnO nanorod synthesis because defect on developing nano-device can be avoided. Development of nano-device with minimal defect is essential to ensure that the performances of the nano device is optimum for sensing bio-molecular substances. Zinc oxide has become the most remarkable choice among other metal oxides semiconductor due to many criteria such as economical cost, unique physical and electrical properties and biocompatible. Initially, ZnO thin films was prepared by using sol gel method. The ZnO seed solution was prepared using conventional sol-gel route. Zinc oxide solution was prepared in two different solvents which are isopropanol (IPA) and methanol (MeOH) in order to investigate the influence of solvent to the quality of ZnO nanorods. MEA, the sol stabilizer was added to the solution for the following 2 hours. Aluminum IDE electrode was deposited on the silicon wafer sample <;100> using traditional wet etching method. Positive photoresist (PR) was coated on the silicon wafer and followed with soft back for 90 seconds. IDE pattern transfer was done by exposing UV light (365nm) onto the PR for 10 seconds. After that, developing and etching process occurred for pattern transfer the IDE electrode onto the silicon wafer. The prepared seed solution was coated on silicon wafer by using speed coating method. Some of the coated samples underwent annealing process at temperature 2000C for 2 hours. The annealed and non-annealed sample undergoes hydrothermal growth method to synthesize ZnO nanorods. The synthesized nanorods underwent I-V test and capacitances to investigate the electrical behavior of ZnO nanorods. The annealed ZnO nanorods provided higher current, which was 900μA, as compared the non-annealed ZnO nanorods which was only 55 μA.
采用水热法合成氧化锌纳米棒,工艺简单,低温处理温度为930℃。低温工艺对于ZnO纳米棒的合成是至关重要的,因为低温工艺可以避免在制备纳米器件时出现缺陷。开发缺陷最小的纳米器件是保证纳米器件在传感生物分子物质时具有最佳性能的关键。氧化锌因其经济的成本、独特的物理和电学性能以及生物相容性等诸多标准而成为半导体金属氧化物中最引人注目的选择。首先,采用溶胶-凝胶法制备ZnO薄膜。采用常规溶胶-凝胶法制备ZnO种子溶液。在异丙醇(IPA)和甲醇(MeOH)两种不同溶剂中制备氧化锌溶液,考察溶剂对氧化锌纳米棒质量的影响。MEA,在溶液中加入溶胶稳定剂2小时。采用传统的湿法刻蚀法在硅片样品上沉积铝IDE电极。将正性光刻胶(PR)涂在硅片上,然后用软背涂敷90秒。将紫外光(365nm)照射在PR上10秒,完成IDE图案转移。然后,将IDE电极的图案转移到硅片上,进行显影和蚀刻过程。将制备好的种子溶液用快速镀膜法涂覆在硅片上。部分包覆样品在2000℃下退火2小时。对退火和未退火样品进行水热生长法制备ZnO纳米棒。对合成的纳米棒进行了I-V测试和电容测试,研究了ZnO纳米棒的电学行为。与未退火ZnO纳米棒相比,退火ZnO纳米棒提供了更高的电流,为900μA,而未退火ZnO纳米棒只有55 μA。
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引用次数: 1
Design and optimization of magnetic particles embedded in PDMS membrane PDMS膜中磁性微粒的设计与优化
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706463
M. Said, J. Yunas, B. Majlis, B. Bais, A. A. Hamzah
A design and optimization of the magnetic particles embedded inside a flexible membrane and factors contributing to the membrane performance have been studied. In this work, Nickel (Ni) is used as magnetic particles and Polydimethylsiloxane (PDMS) is used for membrane material which is considered a matrix component of the flexible membrane. Ni particles with various particle sizes, arrangement and spaces between Ni particles are simulated by using Comsol Multiphysics 4.2. As a result, the optimum design of magnetic particles embedded in membrane for large deflection is by having circular shape membrane with low density of tiny magnetic particles in planar distribution. A preliminary simulation result has been also compared with the theoretical calculation to validate the analysis.
研究了柔性膜内磁性微粒的设计与优化,以及影响柔性膜性能的因素。在这项工作中,镍(Ni)被用作磁性颗粒,聚二甲基硅氧烷(PDMS)被用作膜材料,被认为是柔性膜的基质成分。利用Comsol Multiphysics 4.2软件模拟了不同粒径、不同排列方式和不同间距的Ni粒子。因此,大挠度磁颗粒嵌入膜的最佳设计是采用圆形膜,微磁颗粒密度低,呈平面分布。初步的仿真结果与理论计算结果进行了比较,验证了分析的正确性。
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引用次数: 4
Spherical to polyhedral Pt nanocrystal formation assisted with methylamine 甲胺辅助形成球形到多面体的铂纳米晶体
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706542
M. Ooi, A. Aziz
Nanocrystalline Pt particles synthesized by solvothermal technique assisted with methylamine were investigated. The effect of different amounts of methylamine on the formation of Pt nanocrystal were characterized and elaborated. Small and spherical - like particles were observed for Pt synthesized under the low amount (0.10 mL) of methylamine whilst, concave polyhedral Pt nanocrystal with high - index {411} facets were observed for Pt synthesized under high amount (0.20 mL) of methylamine. The synthesized concave Pt nanocrystal exhibit high absorption peak at 215 nm corresponding to colloidal Pt. The synthesized concave polyhedral structures could be used as a potential catalyst in fuel cells application.
研究了甲胺辅助溶剂热法制备纳米晶铂颗粒。研究了不同量的甲胺对铂纳米晶形成的影响。在低剂量(0.10 mL)甲胺条件下,合成的Pt呈小球形颗粒;在高剂量(0.20 mL)甲胺条件下,合成的Pt呈凹形多面体纳米晶体,具有高折射率{411}切面。所合成的凹形Pt纳米晶体在215 nm处具有较高的吸收峰,与胶体Pt相对应。所合成的凹形多面体结构可作为一种潜在的燃料电池催化剂应用。
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引用次数: 1
Effect of annealing temperature on electrical and optical properties of ZnO thin films prepared by sol gel method 退火温度对溶胶-凝胶法制备ZnO薄膜电学和光学性能的影响
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706515
M. Hannas, A. Manut, Nurul Hafizah A. Rahman, A. B. Rosli, M. Rusop
In this work, ZnO thin films were deposited on glass substrates using spin coating method. Different annealing temperature from 400 to 550°C significantly distresses the nature of electrical and optical properties of ZnO thin films have been investigated. The effect of annealing temperature on optical and electrical properties of nanostuctured ZnO thin films deposited by spin coating method has been studied. The optical properties were characterized by ultraviolet visible (UV-VIS-NIR) spectrophotometer. The electrical properties were analyzed using I-V measurement (CEP 2000). Gold (Au) was used as a metal contact using electron beam thermal evaporator (ULVAC). The optical transmittance spectrums showed the average transmittance of ZnO thin film with different annealing temperature higher than 90% in visible wavelength region. The optical band properties of the nanostructured ZnO thin films were analyzed by UV Vis and Tauc method was accepted to estimate the optical gap and absorption coefficient. The resistivity of the film decreased as the annealing temperature increased from 400 to 550oC. The highest conductivity values of ZnO thin film was obtained at 500°C with value 0.000197 Scm-1. Moreover, the higher porosity was found at 400oC with value 57.5%. The higher porosity of ZnO thin film can be expected the high sensitivity for gas sensor due to the material has a comparatively large surface area.
本研究采用自旋镀膜法在玻璃基板上沉积ZnO薄膜。研究了400 ~ 550℃不同退火温度对ZnO薄膜电学和光学性质的影响。研究了退火温度对自旋镀膜法制备纳米ZnO薄膜光电性能的影响。用紫外可见分光光度计(UV-VIS-NIR)表征了其光学性质。利用I-V测量(CEP 2000)分析了其电性能。利用电子束热蒸发器(ULVAC),采用金(Au)作为金属触点。透射光谱显示,不同退火温度下ZnO薄膜在可见光区的平均透射率均高于90%。采用紫外可见光谱分析了纳米结构ZnO薄膜的光学带性质,并采用tac法估计了其光隙和吸收系数。从400℃到550℃,薄膜的电阻率随退火温度的升高而降低。ZnO薄膜在500℃时电导率最高,为0.000197 cm-1。在400℃时孔隙率较高,为57.5%。由于ZnO薄膜具有较大的表面积,因此其孔隙率越高,气体传感器的灵敏度越高。
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引用次数: 6
Fabrication of multi-walled carbon nanotubes hydrogen sensor on plastic 塑料上多壁碳纳米管氢传感器的制备
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706539
M. M. Ramli, S. S. Isa, S. Henley
Vacuum filtration method was applied to build optically homogeneous film of palladium (Pd) nanoparticles dispersed multi-walled carbon nanotubes (MWCNTs) networks on plastic substrate. Measurement of the sheet resistance as a function of MWCNTs concentration showed a transition from 2D percolation to 3D conduction behaviour when the concentration of MWCNTs exceeded 0.015 mg/ml. The electrical response to H2 gas exposure was investigated at room temperature.
采用真空过滤法在塑料衬底上构建了钯纳米粒子分散的多壁碳纳米管(MWCNTs)光学均匀膜。当MWCNTs浓度超过0.015 mg/ml时,薄片电阻随MWCNTs浓度的变化从二维渗透行为转变为三维传导行为。研究了室温下氢气暴露的电响应。
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引用次数: 3
Characterization direct bonding of SiC/SiN layer on Si wafer for MEMS capacitive pressure sensor MEMS电容式压力传感器硅片上SiC/SiN层直接键合的表征
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706470
Noraini Marsi, B. Majlis, A. A. Hamzah, Faisal Mohd Yasin
Two silicon wafer size of 2.5 mm × 2.5 mm with 1 μm LPCVD silicon carbide (SiC) and 200 nm LPCVD silicon nitride, respectively has been characterize direct bonding between silicon nitride and silicon carbide surfaces. Chemical-mechanical polishing (CMP) treatment processes were performed to reduce the surface roughness of both surfaces before the surface are bonded to each other. The surface roughness shows about 1 μm before CMP treatment, while the smoothness of the surface roughness values as low as 20 nm was obtained after CMP treatment as measured by infinite focus microscopy (IFM). The interface between SiC/SiN layers on Si wafer was inspected by scanning electron microscopy (SEM). Heat treatment with different annealing temperatures is indentified that an optimized annealing process was at 400 °C for 2 hours to allow the bond-forming interface between silicon nitride and silicon carbide surfaces being bonded at 8.3467 MPa.
用1 μm LPCVD碳化硅(SiC)和200 nm LPCVD氮化硅分别制备了两种尺寸为2.5 mm × 2.5 mm的硅片,表征了氮化硅与碳化硅表面的直接键合。采用化学机械抛光(CMP)处理工艺,在表面粘合之前降低两个表面的表面粗糙度。CMP处理前的表面粗糙度约为1 μm,而无限聚焦显微镜(IFM)测量CMP处理后的表面粗糙度值低至20 nm。用扫描电镜(SEM)观察了硅片上SiC/SiN层之间的界面。确定了不同退火温度下的热处理工艺,最优退火工艺为在8.3467 MPa的温度下,在400℃下,保温2小时,使氮化硅和碳化硅表面之间形成键合界面。
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引用次数: 1
High frequency small signal modeling of CNTFET CNTFET高频小信号建模
Pub Date : 2013-09-01 DOI: 10.1109/RSM.2013.6706547
S. Farhana, A. Alam, Sheroz Khan
In this paper, we describe the development of small signal model of a CNTFET. The development consist of high frequency response of CNTFET. The CNTFET generates higher output rather than the conventional Si MOSFET. An SPICE model for enhancement mode Carbon nanotube transistor has been developed. The performance analysis of the CNTFET shows the desirable performance parameter in terms of 10 Thz frequency with 1.8 mS.
本文描述了CNTFET小信号模型的发展。CNTFET的发展包括高频响应。CNTFET产生比传统的Si MOSFET更高的输出。建立了一种用于增强模式碳纳米管晶体管的SPICE模型。通过对CNTFET的性能分析,得出了理想的10thz频率下1.8 mS的性能参数。
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引用次数: 6
期刊
RSM 2013 IEEE Regional Symposium on Micro and Nanoelectronics
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