首页 > 最新文献

Human Nutrition and Metabolism最新文献

英文 中文
Comparison between Amino Acid Profiling of Structural Proteins of earliest and recent omicron strain of SARS-CoV-2 and Nutritional Burden on COVID-19 patients 最早和最新的SARS-CoV-2奥密克戎毒株结构蛋白氨基酸谱与新冠肺炎患者营养负担的比较
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-10-08 DOI: 10.1016/j.hnm.2023.200220
Vivek Ambade , Sonia Ambade , Vaibhav Sharma , Prasanna Sanas

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has four structural proteins. Inside human host cell, it replicates, for which each requires all the structural proteins, and to generate these, entire requirement of amino acids is borne by the host. There is no data regarding amino acid profiling, variation in strains, and its actual burden on the human host. Profiling, with its therapeutic utility, was studied using genomics and proteomics of earliest Wuhan strain and was compared with the recent emerging heavily mutated variant of concern, Omicron. With each replicating SARS-CoV-2 consuming a considerable percentage of essential amino acids (EAAs), coronavirus infection causes huge burden of EAAs on the entire human body in generating billions and billions of SARS-CoV-2 and can cause depletion of body protein stores. The complete amino acid profiling of the structural proteins of SARS-CoV-2 can act as benchmark for designing the correct nutritional supplements for the management of nutritional burden on the patients with SARS-CoV-2 infection.

严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)有四种结构蛋白。在人类宿主细胞内,它进行复制,每种复制都需要所有的结构蛋白,而为了产生这些结构蛋白,对氨基酸的全部需求都由宿主承担。没有关于氨基酸图谱、菌株变异及其对人类宿主的实际负担的数据。利用最早武汉毒株的基因组学和蛋白质组学研究了基因图谱及其治疗效用,并将其与最近出现的令人担忧的严重变异株奥密克戎进行了比较。由于每一种复制的严重急性呼吸系统综合征冠状病毒2型都消耗相当大比例的必需氨基酸(EAA),冠状病毒感染会在整个人体上造成巨大的EAA负担,产生数十亿严重急性呼吸系统冠状病毒2型,并可能导致身体蛋白质储存的耗尽。严重急性呼吸系统综合征冠状病毒2型结构蛋白的完整氨基酸图谱可以作为设计正确营养补充剂的基准,用于管理严重急性呼吸系冠状病毒2型感染患者的营养负担。
{"title":"Comparison between Amino Acid Profiling of Structural Proteins of earliest and recent omicron strain of SARS-CoV-2 and Nutritional Burden on COVID-19 patients","authors":"Vivek Ambade ,&nbsp;Sonia Ambade ,&nbsp;Vaibhav Sharma ,&nbsp;Prasanna Sanas","doi":"10.1016/j.hnm.2023.200220","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200220","url":null,"abstract":"<div><p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has four structural proteins. Inside human host cell, it replicates, for which each requires all the structural proteins, and to generate these, entire requirement of amino acids is borne by the host. There is no data regarding amino acid profiling, variation in strains, and its actual burden on the human host. Profiling, with its therapeutic utility, was studied using genomics and proteomics of earliest Wuhan strain and was compared with the recent emerging heavily mutated variant of concern, Omicron. With each replicating SARS-CoV-2 consuming a considerable percentage of essential amino acids (EAAs), coronavirus infection causes huge burden of EAAs on the entire human body in generating billions and billions of SARS-CoV-2 and can cause depletion of body protein stores. The complete amino acid profiling of the structural proteins of SARS-CoV-2 can act as benchmark for designing the correct nutritional supplements for the management of nutritional burden on the patients with SARS-CoV-2 infection.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200220"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition therapy in critically ill patients with traumatic brain injury 危重颅脑损伤患者的营养治疗
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-25 DOI: 10.1016/j.hnm.2023.200219
Shahmini Ganesh, Noor Airini Ibrahim

Road traffic collisions are the commonest cause of traumatic brain injury (TBI). Patients with brain injury may present with a wide range of symptoms depending on nature and types of injury. Generally, severity of TBI can be classified into mild, moderate and severe based on Glasgow Coma Scale (GCS). This scoring system objectively describes the extent of impaired consciousness. Score of 8 or below indicates severe TBI and will require admission to intensive care and mechanical ventilation. These patients experience significant metabolic changes as a result of excessive production of endogenous catabolic hormones following the injury. Nutritional requirements among these patients differ based on severity of trauma and phase of illness. Timely initiation of feed and addressing individualised nutritional needs can prevent malnutrition. Apart from that, nutrition plays a very important role in neuronal recovery and directly affects neuronal plasticity thus the prognosis. Early involvement of nutritional support as a part of comprehensive care is the key to recovery and better outcome. The aim of this review is to provide an overview of the current evidence-based nutrition therapy for patients with TBI in critical care settings. The review covers the energy and nutrient requirements, enteral and parenteral nutrition, and challenges associated with it.

道路交通碰撞是创伤性脑损伤(TBI)最常见的原因。脑损伤患者可能表现出广泛的症状,这取决于损伤的性质和类型。一般来说,根据格拉斯哥昏迷量表(GCS),TBI的严重程度可分为轻度、中度和重度。这个评分系统客观地描述了意识受损的程度。8分或以下表示严重的TBI,需要接受重症监护和机械通气。由于损伤后内源性分解代谢激素的过度产生,这些患者经历了显著的代谢变化。这些患者的营养需求因创伤的严重程度和疾病的阶段而异。及时开始喂食并满足个性化的营养需求可以防止营养不良。此外,营养在神经元恢复中起着非常重要的作用,并直接影响神经元的可塑性,从而影响预后。作为全面护理的一部分,尽早参与营养支持是恢复和取得更好结果的关键。这篇综述的目的是概述目前在重症监护环境中针对TBI患者的循证营养治疗。综述包括能量和营养需求,肠内和肠外营养,以及与之相关的挑战。
{"title":"Nutrition therapy in critically ill patients with traumatic brain injury","authors":"Shahmini Ganesh,&nbsp;Noor Airini Ibrahim","doi":"10.1016/j.hnm.2023.200219","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200219","url":null,"abstract":"<div><p>Road traffic collisions are the commonest cause of traumatic brain injury (TBI). Patients with brain injury may present with a wide range of symptoms depending on nature and types of injury. Generally, severity of TBI can be classified into mild, moderate and severe based on Glasgow Coma Scale (GCS). This scoring system objectively describes the extent of impaired consciousness. Score of 8 or below indicates severe TBI and will require admission to intensive care and mechanical ventilation. These patients experience significant metabolic changes as a result of excessive production of endogenous catabolic hormones following the injury. Nutritional requirements among these patients differ based on severity of trauma and phase of illness. Timely initiation of feed and addressing individualised nutritional needs can prevent malnutrition. Apart from that, nutrition plays a very important role in neuronal recovery and directly affects neuronal plasticity thus the prognosis. Early involvement of nutritional support as a part of comprehensive care is the key to recovery and better outcome. The aim of this review is to provide an overview of the current evidence-based nutrition therapy for patients with TBI in critical care settings. The review covers the energy and nutrient requirements, enteral and parenteral nutrition, and challenges associated with it.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200219"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The association of vitamin C and vitamin D status on bone mineral density and VCAM-1 levels in female diabetic subjects: Is combined supplementation with vitamin C and vitamin D potentially more successful in improving bone health than supplementation with vitamin D alone? 维生素C和维生素D状态与女性糖尿病受试者骨密度和VCAM-1水平的关系:与单独补充维生素D相比,联合补充维生素C和D在改善骨骼健康方面是否更成功?
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-25 DOI: 10.1016/j.hnm.2023.200221
Christopher M. Stevens, Kamal Bhusal, Steven N. Levine, Richa Dhawan, Sushil K. Jain

Bone mineral density (BMD), which is used to assess bone health, is often diminished in chronic disease states, such as diabetes, which increases the risk of bone fracture. The circulating vitamin C and 25-hydroxy-vitamin D levels are commonly lower in diabetic patients. Vitamin D is implicated in bone formation, while vitamin C has been shown to inhibit osteoclastic activity. Vascular cell adhesion molecule-1 (VCAM-1) promotes osteoclastic activity and bone loss. This study investigated whether any association exists between vitamin C and vitamin D status and BMD and VCAM-1 levels in female diabetic subjects (n = 65). 25-hydroxy-vitamin D had no significant relationship with either BMD or VCAM-1 levels. However, vitamin C showed a significant positive association with BMD and a negative association with VCAM-1. This suggests that combined supplementation with vitamin D and vitamin C, rather than supplementation with vitamin D alone, could be a better strategy for the improvement of bone health and thus deserves further investigation.

用于评估骨骼健康的骨密度(BMD)在糖尿病等慢性疾病状态下通常会降低,这会增加骨折的风险。糖尿病患者的循环维生素C和25-羟基维生素D水平通常较低。维生素D与骨形成有关,而维生素C已被证明能抑制破骨细胞活性。血管细胞粘附分子-1(VCAM-1)促进破骨细胞活性和骨丢失。本研究调查了女性糖尿病受试者(n=65)的维生素C和维生素D状态与BMD和VCAM-1水平之间是否存在任何关联。25-羟基维生素D与骨密度或VCAM-1水平均无显著关系。然而,维生素C与骨密度呈正相关,与VCAM-1呈负相关。这表明,联合补充维生素D和维生素C,而不是单独补充维生素D,可能是改善骨骼健康的更好策略,因此值得进一步研究。
{"title":"The association of vitamin C and vitamin D status on bone mineral density and VCAM-1 levels in female diabetic subjects: Is combined supplementation with vitamin C and vitamin D potentially more successful in improving bone health than supplementation with vitamin D alone?","authors":"Christopher M. Stevens,&nbsp;Kamal Bhusal,&nbsp;Steven N. Levine,&nbsp;Richa Dhawan,&nbsp;Sushil K. Jain","doi":"10.1016/j.hnm.2023.200221","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200221","url":null,"abstract":"<div><p>Bone mineral density (BMD), which is used to assess bone health, is often diminished in chronic disease states, such as diabetes, which increases the risk of bone fracture. The circulating vitamin C and 25-hydroxy-vitamin D levels are commonly lower in diabetic patients. Vitamin D is implicated in bone formation, while vitamin C has been shown to inhibit osteoclastic activity. Vascular cell adhesion molecule-1 (VCAM-1) promotes osteoclastic activity and bone loss. This study investigated whether any association exists between vitamin C and vitamin D status and BMD and VCAM-1 levels in female diabetic subjects (n = 65). 25-hydroxy-vitamin D had no significant relationship with either BMD or VCAM-1 levels. However, vitamin C showed a significant positive association with BMD and a negative association with VCAM-1. This suggests that combined supplementation with vitamin D and vitamin C, rather than supplementation with vitamin D alone, could be a better strategy for the improvement of bone health and thus deserves further investigation.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"34 ","pages":"Article 200221"},"PeriodicalIF":0.0,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49783514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caffeinated non-alcoholic beverages on the postpartum mental health related to the COVID-19 pandemic by a cross-sectional study in Argentina 阿根廷一项横断面研究显示含咖啡因非酒精饮料对新冠肺炎大流行相关产后心理健康的影响
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200198
Agustín Ramiro Miranda , Mariela Valentina Cortez , Ana Veronica Scotta , Elio Andrés Soria

Purpose

This work aimed to study postpartum mental outcomes and determinants of the intake of caffeinated beverages during the pandemic in women from Argentina.

Methods

This cross-sectional study recruited 619 women who responded to online self-report questionnaires during the first and second waves of COVID-19, including validated instruments (Insomnia Severity Index, Perceived Stress Scale, Postpartum Depression Screening Scale, Memory Complaint Scale, and Breastfeeding Self-Efficacy Scale), and general data. Intake frequency and amount of caffeinated beverages were estimated. Multivariate regression and structural equation models identified associations and effects (p < 0.05).

Results

Women were under social restrictions for 60.39 days, with home and essential activities increasing caffeinated intake. They ingested (mL/d): yerba mate (1457.71), coffee (66.85), tea (67.61), and soft drinks (50.95), which provided 646.20 mg/d of caffeine. Intakes of coffee and yerba mate were higher than pre-pandemic ones. Coffee was positively associated with stress and insomnia, and indirectly linked to higher levels of depression and memory complaints, and lower breastfeeding self-efficacy. Tea showed a similar but weaker association. Yerba mate correlated inversely with depression (through direct pathways), insomnia, and memory complaints (through indirect pathways), promoting breastfeeding self-efficacy. Soft drinks and caffeine did not present significant associations.

Conclusion

Although findings do not imply causation, results suggest that beverages would exhibit caffeine-independent affective and cognitive roles, which might be anxiogenic in the case of coffee and tea (to a lesser extent). Yerba mate showed antidepressant potential. Given that breastfeeding might be compromised during the pandemic, yerba mate intake is promissory to protect postpartum mental health.

目的本研究旨在研究阿根廷妇女在大流行期间摄入含咖啡因饮料的产后心理结果和决定因素。方法本横断面研究招募了619名妇女,她们在COVID-19第一波和第二波期间参与了在线自我报告问卷,包括经过验证的工具(失眠严重程度指数、感知压力量表、产后抑郁筛查量表、记忆抱怨量表和母乳喂养自我效能量表)和一般数据。对含咖啡因饮料的摄入频率和量进行了估计。多元回归和结构方程模型确定了关联和影响(p <0.05)。结果女性受到社交限制的时间为60.39天,家庭和基本活动增加了咖啡因的摄入量。他们摄入(mL/d):马黛茶(1457.71),咖啡(66.85),茶(67.61)和软饮料(50.95),其中提供646.20毫克/天的咖啡因。咖啡和马黛茶的摄入量高于疫情前的水平。咖啡与压力和失眠呈正相关,并间接与更高水平的抑郁和记忆力抱怨以及更低的母乳喂养自我效能感有关。茶也显示出类似但较弱的关联。马黛茶与抑郁(通过直接途径)、失眠和记忆抱怨(通过间接途径)呈负相关,促进母乳喂养的自我效能。软饮料和咖啡因没有明显的关联。结论:虽然研究结果并不意味着因果关系,但结果表明,饮料会表现出与咖啡因无关的情感和认知作用,这可能会在咖啡和茶的情况下(在较小程度上)引起焦虑。马黛茶显示出抗抑郁的潜力。鉴于大流行期间母乳喂养可能受到影响,马黛茶摄入有望保护产后心理健康。
{"title":"Caffeinated non-alcoholic beverages on the postpartum mental health related to the COVID-19 pandemic by a cross-sectional study in Argentina","authors":"Agustín Ramiro Miranda ,&nbsp;Mariela Valentina Cortez ,&nbsp;Ana Veronica Scotta ,&nbsp;Elio Andrés Soria","doi":"10.1016/j.hnm.2023.200198","DOIUrl":"10.1016/j.hnm.2023.200198","url":null,"abstract":"<div><h3>Purpose</h3><p>This work aimed to study postpartum mental outcomes and determinants of the intake of caffeinated beverages during the pandemic in women from Argentina.</p></div><div><h3>Methods</h3><p>This cross-sectional study recruited 619 women who responded to online self-report questionnaires during the first and second waves of COVID-19, including validated instruments (Insomnia Severity Index, Perceived Stress Scale, Postpartum Depression Screening Scale, Memory Complaint Scale, and Breastfeeding Self-Efficacy Scale), and general data. Intake frequency and amount of caffeinated beverages were estimated. Multivariate regression and structural equation models identified associations and effects (p &lt; 0.05).</p></div><div><h3>Results</h3><p>Women were under social restrictions for 60.39 days, with home and essential activities increasing caffeinated intake. They ingested (mL/d): <em>yerba mate</em> (1457.71), coffee (66.85), tea (67.61), and soft drinks (50.95), which provided 646.20 mg/d of caffeine. Intakes of coffee and <em>yerba mate</em> were higher than pre-pandemic ones. Coffee was positively associated with stress and insomnia, and indirectly linked to higher levels of depression and memory complaints, and lower breastfeeding self-efficacy. Tea showed a similar but weaker association. <em>Yerba mate</em> correlated inversely with depression (through direct pathways), insomnia, and memory complaints (through indirect pathways), promoting breastfeeding self-efficacy. Soft drinks and caffeine did not present significant associations.</p></div><div><h3>Conclusion</h3><p>Although findings do not imply causation, results suggest that beverages would exhibit caffeine-independent affective and cognitive roles, which might be anxiogenic in the case of coffee and tea (to a lesser extent). <em>Yerba mate</em> showed antidepressant potential. Given that breastfeeding might be compromised during the pandemic, <em>yerba mate</em> intake is promissory to protect postpartum mental health.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200198"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46790814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of serum ergothioneine with alcohol consumption and serum asymmetric dimethyl-l-arginine among middle-aged and older adults in the Hunter Community Study Hunter社区研究中老年人群血清麦角硫因与酒精消耗和血清不对称二甲基精氨酸的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200213
Salvatore Sotgia , Arduino A. Mangoni , Stephen Hancock , Angelo Zinellu , Ciriaco Carru , Mark McEvoy

Among plasma metabolites linked with a health-conscious food pattern (HCFP) identified in the Malmö Diet and Cancer epidemiological study, circulating ergothioneine (ERT) concentrations exhibited the strongest independent association with reduced risk of cardiometabolic disease and all-cause mortality and were also related to alcohol consumption. Thus, we first assessed whether alcohol intake and ERT were similarly associated in participants of the Hunter Community Study (HCS) that did not follow an HCFP-based diet. Then, we sought to identify the presence of associations with some biomarkers associated with cardiovascular disease. In a multivariable adjusted, robust regression analysis, compared to non-drinkers, safe drinkers had, on average, a serum ERT concentration 0.112 (95% CI: 0.0–0.225; P = 0.051) units higher and moderate-hazardous drinkers had a serum ERT concentration 0.240 (95% CI: 0.093–0.387; P = 0.001) units higher. Moreover, stepwise multiple linear regression shows that age (P = 0.025), and asymmetric dimethyl-l-arginine (ADMA) (P = 0.001) were independently associated with serum ERT concentrations, independently of age, sex, education, household income, marital status, and health status of participants, or possible alcohol-induced organ damage. The relationship between ERT and ADMA offers a potential explanation for the interplay between ERT, and decreased risk of cardiometabolic disease and all-cause mortality. Also, it provides new mechanistic insights into the association between alcohol consumption and cardiovascular diseases, possibly mediated by ADMA metabolic pathways.

在MalmöDiet和癌症流行病学研究中发现的与健康意识食物模式(HCFP)相关的血浆代谢物中,循环麦角硫酮(ERT)浓度与心脏代谢疾病风险和全因死亡率的降低表现出最强的独立相关性,也与饮酒有关。因此,我们首先评估了不遵循基于氟氯烃的饮食的猎人社区研究(HCS)参与者的酒精摄入和ERT是否相似。然后,我们试图确定与心血管疾病相关的一些生物标志物的相关性。在一项多变量调整的稳健回归分析中,与不饮酒者相比,安全饮酒者的血清ERT浓度平均高出0.112(95%CI:0.0-0.225;P=0.051)个单位,中度危险饮酒者的血浆ERT浓度高出0.240(95%CI:0.093-0.387;P=0.001)个单位。此外,逐步多元线性回归显示,年龄(P=0.025)和不对称二甲基-1-精氨酸(ADMA)(P=0.001)与血清ERT浓度独立相关,与参与者的年龄、性别、教育程度、家庭收入、婚姻状况和健康状况或可能的酒精诱导的器官损伤无关。ERT和ADMA之间的关系为ERT与降低心脏代谢疾病风险和全因死亡率之间的相互作用提供了潜在的解释。此外,它还为饮酒与心血管疾病之间的联系提供了新的机制见解,可能是由ADMA代谢途径介导的。
{"title":"Association of serum ergothioneine with alcohol consumption and serum asymmetric dimethyl-l-arginine among middle-aged and older adults in the Hunter Community Study","authors":"Salvatore Sotgia ,&nbsp;Arduino A. Mangoni ,&nbsp;Stephen Hancock ,&nbsp;Angelo Zinellu ,&nbsp;Ciriaco Carru ,&nbsp;Mark McEvoy","doi":"10.1016/j.hnm.2023.200213","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200213","url":null,"abstract":"<div><p>Among plasma metabolites linked with a health-conscious food pattern (HCFP) identified in the Malmö Diet and Cancer epidemiological study, circulating ergothioneine (ERT) concentrations exhibited the strongest independent association with reduced risk of cardiometabolic disease and all-cause mortality and were also related to alcohol consumption. Thus, we first assessed whether alcohol intake and ERT were similarly associated in participants of the Hunter Community Study (HCS) that did not follow an HCFP-based diet. Then, we sought to identify the presence of associations with some biomarkers associated with cardiovascular disease. In a multivariable adjusted, robust regression analysis, compared to non-drinkers, safe drinkers had, on average, a serum ERT concentration 0.112 (95% CI: 0.0–0.225; P = 0.051) units higher and moderate-hazardous drinkers had a serum ERT concentration 0.240 (95% CI: 0.093–0.387; P = 0.001) units higher. Moreover, stepwise multiple linear regression shows that age (P = 0.025), and asymmetric dimethyl-<span>l</span>-arginine (ADMA) (P = 0.001) were independently associated with serum ERT concentrations, independently of age, sex, education, household income, marital status, and health status of participants, or possible alcohol-induced organ damage. The relationship between ERT and ADMA offers a potential explanation for the interplay between ERT, and decreased risk of cardiometabolic disease and all-cause mortality. Also, it provides new mechanistic insights into the association between alcohol consumption and cardiovascular diseases, possibly mediated by ADMA metabolic pathways.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200213"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of meat products for the nutrition of the elderly 开发适合老年人营养的肉制品
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200201
Sholpan Abzhanova , Lyazzat Baybolova , Gulshat Zhaksylykova , Aigul Tayeva , Talgat Kulazhanov

Purpose

Due to the increased risk of diseases and digestive disorders, a balanced diet for the elderly is necessary for their well-being and health. Understanding the effects of meat consumption is especially important for older adults, who can benefit from whole-food protein to compensate for age-related loss of muscle mass and strength. The purpose of this study is to analyse the production of meat products and establish the effect of ostrich meat in the nutrition of the elderly.

Methods

The theoretical basis of this study included conclusions and basic recommendations from researchers who explore elderly nutrition, and data from the World Health Organization and the Ministry of Health of the Republic of Kazakhstan. Moreover, research on the nutritional value of ostrich meat pate as a possible component of the diet was conducted, and beef pate was used as a control sample.

Results

The study found that ostrich meat pate has a high nutritional value and lower caloric content compared with beef pate, with high protein content and low-fat content. In addition, ostrich pate is very valuable for its content of fatty acids: arachidonic, linoleic, linoleic, and oleic.

Conclusion

The findings of the study allow to state that ostrich meat is a dietary and low-calorie product that can be recommended for the elderly. The practical value of the study lies in the optimisation of data on the development of meat products for the nutrition of the elderly and the possible inclusion of ostrich meat in the diet.

由于疾病和消化系统紊乱的风险增加,均衡的饮食对老年人的健康和福祉是必要的。了解肉类消费的影响对老年人尤其重要,他们可以从全食物蛋白质中受益,以弥补与年龄相关的肌肉质量和力量损失。本研究的目的是分析肉制品的生产,并确定鸵鸟肉在老年人营养中的作用。方法本研究的理论基础包括老年人营养研究人员的结论和基本建议,以及世界卫生组织和哈萨克斯坦共和国卫生部的数据。此外,还对鸵鸟肉酱作为饲粮的可能成分进行了营养价值研究,并以牛肉酱作为对照样品。结果研究发现,与牛肉酱相比,鸵鸟肉酱营养价值高,热量含量低,蛋白质含量高,脂肪含量低。此外,鸵鸟肉酱还富含花生四烯酸、亚油酸、亚油酸和油酸等脂肪酸。结论:研究结果表明,鸵鸟肉是一种低热量的膳食产品,可以推荐给老年人。该研究的实用价值在于优化了老年人营养肉制品开发的数据,并可能将鸵鸟肉纳入饮食中。
{"title":"Development of meat products for the nutrition of the elderly","authors":"Sholpan Abzhanova ,&nbsp;Lyazzat Baybolova ,&nbsp;Gulshat Zhaksylykova ,&nbsp;Aigul Tayeva ,&nbsp;Talgat Kulazhanov","doi":"10.1016/j.hnm.2023.200201","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200201","url":null,"abstract":"<div><h3>Purpose</h3><p>Due to the increased risk of diseases and digestive disorders, a balanced diet for the elderly is necessary for their well-being and health. Understanding the effects of meat consumption is especially important for older adults, who can benefit from whole-food protein to compensate for age-related loss of muscle mass and strength. The purpose of this study is to analyse the production of meat products and establish the effect of ostrich meat in the nutrition of the elderly.</p></div><div><h3>Methods</h3><p>The theoretical basis of this study included conclusions and basic recommendations from researchers who explore elderly nutrition, and data from the World Health Organization and the Ministry of Health of the Republic of Kazakhstan. Moreover, research on the nutritional value of ostrich meat pate as a possible component of the diet was conducted, and beef pate was used as a control sample.</p></div><div><h3>Results</h3><p>The study found that ostrich meat pate has a high nutritional value and lower caloric content compared with beef pate, with high protein content and low-fat content. In addition, ostrich pate is very valuable for its content of fatty acids: arachidonic, linoleic, linoleic, and oleic.</p></div><div><h3>Conclusion</h3><p>The findings of the study allow to state that ostrich meat is a dietary and low-calorie product that can be recommended for the elderly. The practical value of the study lies in the optimisation of data on the development of meat products for the nutrition of the elderly and the possible inclusion of ostrich meat in the diet.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200201"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49901483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Education programs for gestational diabetes mellitus: A systematic review 妊娠期糖尿病的教育计划:一项系统综述
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200195
Ozlem Akalpler , Ezgi Bagriacik

Gestational diabetes mellitus is one of the most common metabolic diseases during pregnancy and is a condition that needs to be handled carefully because it brings significant risks for maternal, fetal and neonatal health. In this systematic review, we aimed to examine randomized controlled trials evaluating the effect of different educational programs applied to pregnant women with gestational diabetes mellitus on the management of the disease. Between November and December 2022, Google Scholar, EBSCOhost/CINAHL Complete, PubMed, Scopus, Science Direct, Web of Science and Cochrane Library databases were searched with the keywords ‘gestational, diabetes mellitus, management, randomized controlled trials'. As a result of the search, 2859 articles were found. In the schematic review, 11 randomized controlled trials, the full text of which was available, which were conducted between 2017 and 2022, were included. It was found that diabetes education given to pregnant women had a positive effect on quality of life and self-efficacy. It was observed that the babies of women who received education had fewer complications compared to the control group, the blood glucose levels of the pregnant women who received education were significantly lower than those in the control group, and nutritional habits gave significantly desired results in the intervention group.

妊娠期糖尿病是妊娠期最常见的代谢性疾病之一,需要谨慎处理,因为它会给孕产妇、胎儿和新生儿的健康带来重大风险。在这篇系统综述中,我们旨在检查随机对照试验,评估不同教育项目对妊娠期糖尿病孕妇疾病管理的影响。2022年11月至12月,Google Scholar、EBSCOhost/CINAHL Complete、PubMed、Scopus、Science Direct、Web of Science和Cochrane Library数据库以“妊娠期、糖尿病、管理、随机对照试验”为关键词进行了搜索。搜索结果发现2859篇文章。在原理图综述中,包括了2017年至2022年间进行的11项随机对照试验,其全文可用。研究发现,孕妇糖尿病教育对生活质量和自我效能感有积极影响。据观察,与对照组相比,接受教育的妇女的婴儿并发症更少,接受教育孕妇的血糖水平显著低于对照组,营养习惯在干预组中产生了显著的预期效果。
{"title":"Education programs for gestational diabetes mellitus: A systematic review","authors":"Ozlem Akalpler ,&nbsp;Ezgi Bagriacik","doi":"10.1016/j.hnm.2023.200195","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200195","url":null,"abstract":"<div><p>Gestational diabetes mellitus is one of the most common metabolic diseases during pregnancy and is a condition that needs to be handled carefully because it brings significant risks for maternal, fetal and neonatal health. In this systematic review, we aimed to examine randomized controlled trials evaluating the effect of different educational programs applied to pregnant women with gestational diabetes mellitus on the management of the disease. Between November and December 2022, Google Scholar, EBSCOhost/CINAHL Complete, PubMed, Scopus, Science Direct, Web of Science and Cochrane Library databases were searched with the keywords ‘gestational, diabetes mellitus, management, randomized controlled trials'. As a result of the search, 2859 articles were found. In the schematic review, 11 randomized controlled trials, the full text of which was available, which were conducted between 2017 and 2022, were included. It was found that diabetes education given to pregnant women had a positive effect on quality of life and self-efficacy. It was observed that the babies of women who received education had fewer complications compared to the control group, the blood glucose levels of the pregnant women who received education were significantly lower than those in the control group, and nutritional habits gave significantly desired results in the intervention group.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200195"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amino acid and fatty acid profiles of the average Japanese diet: Fusion of the National Health and Nutrition Examination Survey and the Food Composition Database 日本普通膳食的氨基酸和脂肪酸分布:国家健康和营养检查调查与食品成分数据库的融合
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200200
Ayari Tsumura , Hisami Yamanaka-Okumura , Hana Kawakami , Shiori Yamamoto , Mayu Oura , Hirokazu Ohminami , Masashi Masuda , Yutaka Taketani

Objectives

Dietary assessment requires standards, but for the correct evaluation and understanding, not only quantity but also quality; source information is essential. In particular, protein and fat, the major nutrients in the diet, are important to consider from a focused perspective because their constituent amino acids (AA) and fatty acids (FA) themselves are associated with various outcomes. Therefore, we utilized the average nutrient intake data of the Japanese population to construct a profile of the current dietary intake of AA and FA.

Methods

We used daily dietary survey data of approximately 6,000 men and women from the Japanese National Health and Nutrition Survey 2019. The estimated AA and FA intakes of actual diets were calculated by tying the Japanese Food Composition Table, seventh Revision, to approximately 1,500 foods in the food group table, for which inputs are published by category and multiplied by the intake.

Results

Of the 18 total AA, rice, pork, and beef contributed the highest percentage of intake in that order, which were similar for the individual AA. On the other hand, for a total of 47 FA, vegetable oil, pork, and beef were the highest contributors in that order, but the contribution profiles differed among the individuals’ FA. The Japanese had the highest intake of 18:1 total among 47 FA types.

Conclusions

This study clarified the dietary AA and FA profiles of the current average Japanese diet based on the simultaneous assessment of quality and quantity and tied it to the amount and source of intake.

目的饮食评估需要标准,但要有正确的评价和理解,不仅要有数量,还要有质量;来源信息至关重要。特别是,蛋白质和脂肪是饮食中的主要营养素,从集中的角度考虑很重要,因为它们的组成氨基酸(AA)和脂肪酸(FA)本身与各种结果有关。因此,我们利用日本人口的平均营养摄入数据来构建AA和FA的当前饮食摄入概况。方法我们使用了来自2019年日本国民健康和营养调查的约6000名男性和女性的每日饮食调查数据。实际饮食中AA和FA的估计摄入量是通过将《日本食物成分表》第七次修订版与食物组表中约1500种食物联系起来计算的,这些食物组表的输入按类别公布并乘以摄入量。结果在18种总脂肪酸中,大米、猪肉和牛肉的摄入量比例最高,与个体脂肪酸的摄入量比例相似。另一方面,在总共47种FA中,植物油、猪肉和牛的摄入量比例依次最高,但个体脂肪酸之间的贡献程度不同。在47种FA类型中,日本人的总摄入量最高,为18:1。结论本研究在同时评估质量和数量的基础上,阐明了当前日本平均饮食的AA和FA特征,并将其与摄入量和来源联系起来。
{"title":"Amino acid and fatty acid profiles of the average Japanese diet: Fusion of the National Health and Nutrition Examination Survey and the Food Composition Database","authors":"Ayari Tsumura ,&nbsp;Hisami Yamanaka-Okumura ,&nbsp;Hana Kawakami ,&nbsp;Shiori Yamamoto ,&nbsp;Mayu Oura ,&nbsp;Hirokazu Ohminami ,&nbsp;Masashi Masuda ,&nbsp;Yutaka Taketani","doi":"10.1016/j.hnm.2023.200200","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200200","url":null,"abstract":"<div><h3>Objectives</h3><p>Dietary assessment requires standards, but for the correct evaluation and understanding, not only quantity but also quality; source information is essential. In particular, protein and fat, the major nutrients in the diet, are important to consider from a focused perspective because their constituent amino acids (AA) and fatty acids (FA) themselves are associated with various outcomes. Therefore, we utilized the average nutrient intake data of the Japanese population to construct a profile of the current dietary intake of AA and FA.</p></div><div><h3>Methods</h3><p>We used daily dietary survey data of approximately 6,000 men and women from the Japanese National Health and Nutrition Survey 2019. The estimated AA and FA intakes of actual diets were calculated by tying the Japanese Food Composition Table, seventh Revision, to approximately 1,500 foods in the food group table, for which inputs are published by category and multiplied by the intake.</p></div><div><h3>Results</h3><p>Of the 18 total AA, rice, pork, and beef contributed the highest percentage of intake in that order, which were similar for the individual AA. On the other hand, for a total of 47 FA, vegetable oil, pork, and beef were the highest contributors in that order, but the contribution profiles differed among the individuals’ FA. The Japanese had the highest intake of 18:1 total among 47 FA types.</p></div><div><h3>Conclusions</h3><p>This study clarified the dietary AA and FA profiles of the current average Japanese diet based on the simultaneous assessment of quality and quantity and tied it to the amount and source of intake.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200200"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between comfort eating and weight change during the COVID-19 pandemic among U.S. adults 美国成年人在COVID-19大流行期间舒适饮食与体重变化之间的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200212
David J. Ederer , Seung Hee Lee , Brook Belay , Kerri Boutelle , Sohyun Park

Objective

To examine associations between comfort eating in response to loneliness or stress and weight change during the COVID-19 pandemic among U.S. adults.

Design

Quantitative, cross-sectional study.

Setting

The 2021 SummerStyles survey data.

Subjects

U.S. adults (≥18 years; N = 4068).

Measures

The outcome was reported weight changes since the start of the COVID-19 pandemic with four responses: lost weight, weight remained the same, gained weight, and don't know. The exposure variable was frequency of comfort eating in response to loneliness or stress during the past year with three responses: never/rarely, sometimes, or often/always.

Analysis

We used chi-square analysis to examine the independence of survey variables related to weight changes, and comfort eating in response to loneliness or stress during the COVID-19 pandemic. Next, we used a multinomial logistic regression to estimate adjusted odds ratios for weight changes by comfort eating in response to loneliness or stress frequency.

Results

Overall, 20.1% of adults reported losing weight, 39.9% remained about the same weight, 30.4% gained weight, and 9.4% did not know about their weight change during the COVID-19 pandemic. Taking comfort by eating in response to loneliness or stress was reported by over 33% of participants (often/always = 8.3%; sometimes = 25.3%). Weight change and comfort eating during the COVID-19 pandemic significantly varied by sociodemographic factors. Respondents that sometimes or often/always reported taking comfort by eating in response to loneliness or stress were more likely to report losing weight (Adjusted Odds Ratio ranges: 1.62–2.99) or gaining weight (Adjusted Odds Ratio ranges: 3.10–4.61) than those who never/rarely took comfort by eating in response to loneliness or stress.

Conclusions

Taking comfort by eating when stressed/lonely was significantly associated with reported weight changes during the COVID-19 pandemic. Weight changes may lead to additional health complications. Implementing evidence-based strategies to reduce loneliness or stress and support healthy eating during the COVID-19 pandemic may benefit weight management and future well-being.

目的研究美国成年人在COVID-19大流行期间应对孤独或压力的安慰性饮食与体重变化之间的关系。设计定量、横断面研究。设置2021年夏季风格调查数据。成人(≥18岁;n = 4068)。结果是自COVID-19大流行开始以来报告的体重变化,有四种反应:体重减轻、体重保持不变、体重增加和不知道。暴露变量是在过去一年中因孤独或压力而吃安慰性食物的频率,有三种反应:从不/很少,有时,经常/总是。分析我们使用卡方分析来检验与体重变化相关的调查变量的独立性,以及在COVID-19大流行期间应对孤独或压力的安慰性饮食。接下来,我们使用多项逻辑回归来估计安慰饮食对孤独或压力频率的体重变化的调整优势比。结果总体而言,20.1%的成年人报告体重减轻,39.9%的人体重保持不变,30.4%的人体重增加,9.4%的人不知道自己在新冠肺炎大流行期间的体重变化。超过33%的参与者(经常/总是= 8.3%;有时= 25.3%)。在2019冠状病毒病大流行期间,体重变化和舒适饮食因社会人口因素而有很大差异。有时或经常/总是报告通过饮食来缓解孤独或压力的受访者比那些从未/很少通过饮食来缓解孤独或压力的受访者更有可能报告体重减轻(调整优势比范围:1.62-2.99)或体重增加(调整优势比范围:3.10-4.61)。结论在COVID-19大流行期间,压力/孤独时通过进食来获得安慰与报告的体重变化显著相关。体重变化可能导致额外的健康并发症。在2019冠状病毒病大流行期间,实施以证据为基础的战略,减少孤独感或压力,支持健康饮食,可能有利于体重管理和未来的福祉。
{"title":"Associations between comfort eating and weight change during the COVID-19 pandemic among U.S. adults","authors":"David J. Ederer ,&nbsp;Seung Hee Lee ,&nbsp;Brook Belay ,&nbsp;Kerri Boutelle ,&nbsp;Sohyun Park","doi":"10.1016/j.hnm.2023.200212","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200212","url":null,"abstract":"<div><h3>Objective</h3><p>To examine associations between comfort eating in response to loneliness or stress and weight change during the COVID-19 pandemic among U.S. adults.</p></div><div><h3>Design</h3><p>Quantitative, cross-sectional study.</p></div><div><h3>Setting</h3><p>The 2021 <em>SummerStyles</em> survey data.</p></div><div><h3>Subjects</h3><p>U.S. adults (≥18 years; N = 4068).</p></div><div><h3>Measures</h3><p>The outcome was reported weight changes since the start of the COVID-19 pandemic with four responses: lost weight, weight remained the same, gained weight, and don't know. The exposure variable was frequency of comfort eating in response to loneliness or stress during the past year with three responses: never/rarely, sometimes, or often/always.</p></div><div><h3>Analysis</h3><p>We used chi-square analysis to examine the independence of survey variables related to weight changes, and comfort eating in response to loneliness or stress during the COVID-19 pandemic. Next, we used a multinomial logistic regression to estimate adjusted odds ratios for weight changes by comfort eating in response to loneliness or stress frequency.</p></div><div><h3>Results</h3><p>Overall, 20.1% of adults reported losing weight, 39.9% remained about the same weight, 30.4% gained weight, and 9.4% did not know about their weight change during the COVID-19 pandemic. Taking comfort by eating in response to loneliness or stress was reported by over 33% of participants (often/always = 8.3%; sometimes = 25.3%). Weight change and comfort eating during the COVID-19 pandemic significantly varied by sociodemographic factors. Respondents that sometimes or often/always reported taking comfort by eating in response to loneliness or stress were more likely to report losing weight (Adjusted Odds Ratio ranges: 1.62–2.99) or gaining weight (Adjusted Odds Ratio ranges: 3.10–4.61) than those who never/rarely took comfort by eating in response to loneliness or stress.</p></div><div><h3>Conclusions</h3><p>Taking comfort by eating when stressed/lonely was significantly associated with reported weight changes during the COVID-19 pandemic. Weight changes may lead to additional health complications. Implementing evidence-based strategies to reduce loneliness or stress and support healthy eating during the COVID-19 pandemic may benefit weight management and future well-being.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200212"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49901485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship of gastroesophageal reflux with nutritional habits and mental disorders 胃食管反流与营养习惯和精神障碍的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2023-09-01 DOI: 10.1016/j.hnm.2023.200203
Aliye Özenoğlu , Nejla Anul , Büşra Özçelikçi

Gastroesophageal reflux disease (GERD) is one of the most common health problems of the upper gastrointestinal system, in which complex biopsychosocial factors play a role in its development. In addition to bad nutritional habits, it is known that psychological stress has aggravating effects on gastroesophageal reflux symptoms. Presenting the current evidence obtained from studies on this subject can be a guide for both clinicians and patients.

The role of various factors such as poor eating habits, obesity, stress, anxiety, sedentary lifestyle, sleep disorders, smoking and alcohol in the etiology of GERD is emphasized. Pharmacotherapy is considered first-line therapy for patients with GERD, but lifestyle modification, including dietary changes, is an important element in supporting the treatment of the disease. However, although lifestyle change offers a more effective, lower cost and less side-effect treatment, it is often seen to be insufficient in practice.

The results of the studies show that reflux is closely related to mental state and eating habits affect both reflux and mood. In the management of GERD, the evaluation of biopsychosocial factors together and the application of a multidisciplinary approach can make a significant contribution to increase the success of the treatment and quality of life.

胃食管反流病(GERD)是上消化道系统最常见的健康问题之一,复杂的生物心理社会因素在其发展过程中起着重要作用。除了不良的营养习惯外,众所周知,心理压力还会加重胃食管反流症状。介绍从这一主题的研究中获得的最新证据可以为临床医生和患者提供指导。强调了不良饮食习惯、肥胖、压力、焦虑、久坐不动的生活方式、睡眠障碍、吸烟和饮酒等各种因素在胃食管反流病病因中的作用。药物治疗被认为是GERD患者的一线治疗,但改变生活方式,包括改变饮食,是支持该疾病治疗的重要因素。然而,尽管生活方式的改变提供了一种更有效、成本更低、副作用更少的治疗方法,但在实践中往往被认为是不够的。研究结果表明,反流与精神状态密切相关,饮食习惯影响反流和情绪。在GERD的管理中,对生物-心理-社会因素的综合评估和多学科方法的应用可以为提高治疗的成功率和生活质量做出重大贡献。
{"title":"The relationship of gastroesophageal reflux with nutritional habits and mental disorders","authors":"Aliye Özenoğlu ,&nbsp;Nejla Anul ,&nbsp;Büşra Özçelikçi","doi":"10.1016/j.hnm.2023.200203","DOIUrl":"https://doi.org/10.1016/j.hnm.2023.200203","url":null,"abstract":"<div><p>Gastroesophageal reflux disease (GERD) is one of the most common health problems of the upper gastrointestinal system, in which complex biopsychosocial factors play a role in its development. In addition to bad nutritional habits, it is known that psychological stress has aggravating effects on gastroesophageal reflux symptoms. Presenting the current evidence obtained from studies on this subject can be a guide for both clinicians and patients.</p><p>The role of various factors such as poor eating habits, obesity, stress, anxiety, sedentary lifestyle, sleep disorders, smoking and alcohol in the etiology of GERD is emphasized. Pharmacotherapy is considered first-line therapy for patients with GERD, but lifestyle modification, including dietary changes, is an important element in supporting the treatment of the disease. However, although lifestyle change offers a more effective, lower cost and less side-effect treatment, it is often seen to be insufficient in practice.</p><p>The results of the studies show that reflux is closely related to mental state and eating habits affect both reflux and mood. In the management of GERD, the evaluation of biopsychosocial factors together and the application of a multidisciplinary approach can make a significant contribution to increase the success of the treatment and quality of life.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"33 ","pages":"Article 200203"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49868142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Human Nutrition and Metabolism
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1