Pub Date : 2025-09-01Epub Date: 2025-05-08DOI: 10.1016/j.hnm.2025.200320
Saltos Atiencia Dayana , Chamba Calva Wilmer
The management of eating disorders (ED) requires a multidisciplinary approach that integrates medical, psychological, and nutritional care. In this context, Mindful Eating (ME) has emerged as a concept gaining increasing attention as a potential adjunctive approach to addressing eating disorders. The aim of this study was to analyze the scientific output related to Mindful Eating in the context of eating disorder management from 2000 to 2025, using a bibliometric analysis. The methodology followed a quantitative, descriptive, and non-experimental approach. The bibliometric study was based on a representative set of scientific articles indexed in the Scopus database. A search string was applied with filters for year, document type, and language to ensure appropriate selection. The analysis was conducted using Bibliometrix (RStudio) for bibliometric measurements and VOSviewer for generating visualizations, graphs, and data mapping. The findings revealed a significant increase in scientific production, with 91 articles published since 2008 and an annual growth rate of 17.39 %. This indicates that Mindful Eating has become a growing research theme, frequently associated with related concepts such as obesity, body weight, bulimia, anorexia, and body image. The study offers a comprehensive overview of the current research landscape, providing a foundation for future investigations into clinical applications and informing the development of hypotheses for targeted interventions.
{"title":"Mindful Eating in the management of eating disorders: A bibliometric study","authors":"Saltos Atiencia Dayana , Chamba Calva Wilmer","doi":"10.1016/j.hnm.2025.200320","DOIUrl":"10.1016/j.hnm.2025.200320","url":null,"abstract":"<div><div>The management of eating disorders (ED) requires a multidisciplinary approach that integrates medical, psychological, and nutritional care. In this context, Mindful Eating (ME) has emerged as a concept gaining increasing attention as a potential adjunctive approach to addressing eating disorders. The aim of this study was to analyze the scientific output related to Mindful Eating in the context of eating disorder management from 2000 to 2025, using a bibliometric analysis. The methodology followed a quantitative, descriptive, and non-experimental approach. The bibliometric study was based on a representative set of scientific articles indexed in the Scopus database. A search string was applied with filters for year, document type, and language to ensure appropriate selection. The analysis was conducted using Bibliometrix (RStudio) for bibliometric measurements and VOSviewer for generating visualizations, graphs, and data mapping. The findings revealed a significant increase in scientific production, with 91 articles published since 2008 and an annual growth rate of 17.39 %. This indicates that Mindful Eating has become a growing research theme, frequently associated with related concepts such as obesity, body weight, bulimia, anorexia, and body image. The study offers a comprehensive overview of the current research landscape, providing a foundation for future investigations into clinical applications and informing the development of hypotheses for targeted interventions.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200320"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144098615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to “Prevalence of hypertension and its associated risk factors during COVID-19 pandemic in the capital of Bangladesh” [Human Nutr. Metabol. 38 (2024) 200289]","authors":"Urmilla Roy , Arafat Hassan Razon , Tanvir Ahamad , Tabassum Sultana Barsha","doi":"10.1016/j.hnm.2025.200334","DOIUrl":"10.1016/j.hnm.2025.200334","url":null,"abstract":"","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200334"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food insecurity is a widespread issue that poses a major global challenge with far-reaching impacts.
Objective
Investigate the relationship between food insecurity and health behaviors among the population of Tacloban, Philippines, affected by Typhoon Haiyan in 2013.
Methods
This study employed a cross-sectional design, surveying 226 households between April 2022 and June 2023. Households were selected using a systematic random sampling technique to ensure representative coverage. To evaluate food insecurity, we utilized the Food Insecurity Experience Scale-a robust tool that captures the degree to which individuals or households face challenges in accessing sufficient and nutritious food due to economic and social constraints. In addition, we explored a variety of health-related behaviors among participants, including the use of traditional healing practices, engagement in physical activity, sleep patterns and duration, dietary habits, medication adherence, as well as alcohol and tobacco use. The relationships between food insecurity and these health behaviors were rigorously examined using multiple logistic regression analysis, providing valuable insights into the interplay between access to food and lifestyle choices within the community.
Results
The results showed that 94 % of households experienced food insecurity, with 27 % severely, 52 % moderately, and 15 % mildly food insecure. The analysis revealed significant associations between food insecurity and several health behaviors. Food insecurity was found to be significantly associated with lower medication adherence, greater use of traditional healers, poorer dietary habits, and sleeping problems. However, no significant associations were found between food insecurity and smoking behavior, physical activities, or alcohol consumption.
Conclusion
Based on these findings, the study concluded that food insecurity negatively impacts health behaviors. Therefore, the authors suggested that improving food security in households could potentially lead to improvements in health behaviors.
{"title":"Food insecurity and health behaviors in a disaster-affected population: A case study of Tacloban, Philippines","authors":"Gashaw Enbiyale Kasse , Abdo Megra Geda , Aregash Wendimu Tumebo , Elvis Akem Tambe , Abraham Belete Temesgen , Mulusew Tesfaye Yitie , Tadesse Mihiret Yimam , Samuel Atalay Shiferaw","doi":"10.1016/j.hnm.2025.200327","DOIUrl":"10.1016/j.hnm.2025.200327","url":null,"abstract":"<div><h3>Background</h3><div>Food insecurity is a widespread issue that poses a major global challenge with far-reaching impacts.</div></div><div><h3>Objective</h3><div>Investigate the relationship between food insecurity and health behaviors among the population of Tacloban, Philippines, affected by Typhoon Haiyan in 2013.</div></div><div><h3>Methods</h3><div>This study employed a cross-sectional design, surveying 226 households between April 2022 and June 2023. Households were selected using a systematic random sampling technique to ensure representative coverage. To evaluate food insecurity, we utilized the Food Insecurity Experience Scale-a robust tool that captures the degree to which individuals or households face challenges in accessing sufficient and nutritious food due to economic and social constraints. In addition, we explored a variety of health-related behaviors among participants, including the use of traditional healing practices, engagement in physical activity, sleep patterns and duration, dietary habits, medication adherence, as well as alcohol and tobacco use. The relationships between food insecurity and these health behaviors were rigorously examined using multiple logistic regression analysis, providing valuable insights into the interplay between access to food and lifestyle choices within the community.</div></div><div><h3>Results</h3><div>The results showed that 94 % of households experienced food insecurity, with 27 % severely, 52 % moderately, and 15 % mildly food insecure. The analysis revealed significant associations between food insecurity and several health behaviors. Food insecurity was found to be significantly associated with lower medication adherence, greater use of traditional healers, poorer dietary habits, and sleeping problems. However, no significant associations were found between food insecurity and smoking behavior, physical activities, or alcohol consumption.</div></div><div><h3>Conclusion</h3><div>Based on these findings, the study concluded that food insecurity negatively impacts health behaviors. Therefore, the authors suggested that improving food security in households could potentially lead to improvements in health behaviors.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200327"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recently, the digitalization of data science in nutrition has highlighted the need for comprehensive dietary databases to interpret dietary habits accurately. Previous studies have elucidated detailed profiles of amino acids (AAs) and fatty acids (FAs) in the Japanese diet beyond the general categories of proteins and lipids. This study aimed to profile the intake of AAs and FAs in the United States (U.S.) population, focusing on the quantity of these nutrients. By linking the USDA National Nutrient Database for Standard Reference with the National Health and Nutrition Examination Survey 2017–March 2020 data, we estimated the average dietary intake of 18 AAs and 19 FAs in the U.S. population, expressed in mg/1000 kcal and calculated their respective contributions. Among the 18 AAs, glutamic acid, aspartic acid, and leucine were the most consumed, accounting for 19.8 %, 9.1 %, and 8.1 % of the total intake, respectively. Among the 19 FAs, 18:1 constituted the most significant proportion at 36.5 %, followed by 18:2 at 23.3 % and 16:0 at 20.1 %. Although the intake contribution profiles of AA were similar across different food groups, those of FA varied significantly. Overall, we successfully developed a database showing the average intake of AA and FA in the U.S. population rather than focusing solely on proteins and lipids. This database provides a foundation for accurately understanding and interpreting dietary habits in the U.S. population and suggests its potential use as a reference for future international dietary comparisons.
{"title":"Analysis of dietary amino acid and fatty acid intake profiles of US adults: NHANES 2017–March 2020 Pre-pandemic","authors":"Miyu Kenzaka , Haruka Nishiyama , Miyuki Imafuku , Sae Nakao , Sari Natsume , Chika Oue , Hisami Yamanaka-Okumura","doi":"10.1016/j.hnm.2025.200329","DOIUrl":"10.1016/j.hnm.2025.200329","url":null,"abstract":"<div><div>Recently, the digitalization of data science in nutrition has highlighted the need for comprehensive dietary databases to interpret dietary habits accurately. Previous studies have elucidated detailed profiles of amino acids (AAs) and fatty acids (FAs) in the Japanese diet beyond the general categories of proteins and lipids. This study aimed to profile the intake of AAs and FAs in the United States (U.S.) population, focusing on the quantity of these nutrients. By linking the USDA National Nutrient Database for Standard Reference with the National Health and Nutrition Examination Survey 2017–March 2020 data, we estimated the average dietary intake of 18 AAs and 19 FAs in the U.S. population, expressed in mg/1000 kcal and calculated their respective contributions. Among the 18 AAs, glutamic acid, aspartic acid, and leucine were the most consumed, accounting for 19.8 %, 9.1 %, and 8.1 % of the total intake, respectively. Among the 19 FAs, 18:1 constituted the most significant proportion at 36.5 %, followed by 18:2 at 23.3 % and 16:0 at 20.1 %. Although the intake contribution profiles of AA were similar across different food groups, those of FA varied significantly. Overall, we successfully developed a database showing the average intake of AA and FA in the U.S. population rather than focusing solely on proteins and lipids. This database provides a foundation for accurately understanding and interpreting dietary habits in the U.S. population and suggests its potential use as a reference for future international dietary comparisons.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200329"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-05-06DOI: 10.1016/j.hnm.2025.200322
Valéria Clarisse de Oliveira , Paola Soledad Mosquera , Tamara Rodrigues dos Santos , Haroldo S. Ferreira , Bárbara H. Lourenço , Marly A. Cardoso
{"title":"Corrigendum to “Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, Brazil” [Hum. Nutr. Metab. 40 (2025) 200318]","authors":"Valéria Clarisse de Oliveira , Paola Soledad Mosquera , Tamara Rodrigues dos Santos , Haroldo S. Ferreira , Bárbara H. Lourenço , Marly A. Cardoso","doi":"10.1016/j.hnm.2025.200322","DOIUrl":"10.1016/j.hnm.2025.200322","url":null,"abstract":"","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200322"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Previous research on probiotics has mainly focused on eczema in infants and pregnant women, with limited benefits observed in adults. Miyarisan, a probiotic known for supporting gut barrier function, has not been extensively studied for its effects on eczema in adult populations.
Methods
We used the TriNetX global network (2014–2024) to compare Miyarisan users with non-users among eczema or dermatitis patients. Propensity score matching (PSM) reduced bias, and hazard ratios (HRs) with 95 % confidence intervals (CIs) and Kaplan-Meier curves assessed skin outcomes based on the SCORAD index. Subgroup analyses explored variations by sex, age, and medication refill frequency, with a sensitivity analysis focusing on atopic dermatitis patients.
Results
Following 1:1 PS M, the study analyzed 1600 cases in each group (Miyarisan users and non-users) without difference between baseline variables. The incidence of itching (HR = 0.372, 95 % CI: 0.287–0.481, p < 0.001), redness (HR = 0.065, 95 % CI: 0.040–0.108, p < 0.001), dryness (HR = 0.358, 95 % CI: 0.285–0.449, p < 0.001), swelling (HR = 0.164, 95 % CI: 0.101–0.265, p < 0.001), scratching (HR = 0.426, 95 % CI: 0.296–0.612, p < 0.001), and thickening (HR = 0.325, 95 % CI: 0.225–0.467, p < 0.001) were significantly lower in the Miyarisan group compared to the non-Miyarisan group. These benefits were consistent across different gender and age subgroups. According to individual SCORAD measures, reduced skin redness was consistently observed across all subgroups. When focusing on atopic dermatitis, Miyarisan users also showed a lower risk of adverse skin outcomes, similar to patients with eczema or dermatitis.
Conclusion
Miyarisan use in adults may reduce the recurrence of eczema or dermatitis, with consistent benefits across both sex and age groups. These findings are also observed in patients with atopic dermatitis.
以往对益生菌的研究主要集中在婴儿和孕妇的湿疹上，对成人的益处有限。Miyarisan是一种以支持肠道屏障功能而闻名的益生菌，其对成人湿疹的影响尚未得到广泛研究。方法采用TriNetX全球网络（2014-2024）对湿疹或皮炎患者中使用Miyarisan和未使用Miyarisan的患者进行比较。倾向评分匹配（PSM）减少了偏倚，95%置信区间（ci）的风险比（hr）和Kaplan-Meier曲线基于SCORAD指数评估皮肤结果。亚组分析探讨了性别、年龄和药物补充频率的变化，并对特应性皮炎患者进行了敏感性分析。结果在1:1 PS M后，研究分析了每组（Miyarisan使用者和非使用者）1600例病例，基线变量之间无差异。瘙痒发生率(HR = 0.372, 95% CI: 0.287-0.481, p <；0.001),红(HR = 0.065, 95%置信区间CI: 0.040 - -0.108, p & lt;0.001),干燥(HR = 0.358, 95%置信区间CI: 0.285 - -0.449, p & lt;0.001)、肿胀(HR = 0.164, 95%置信区间CI: 0.101 - -0.265, p & lt;0.001),抓(HR = 0.426, 95%置信区间CI: 0.296 - -0.612, p & lt;0.001)和增厚(HR = 0.325, 95%置信区间CI: 0.225 - -0.467, p & lt;0.001)，宫崎骏组明显低于非宫崎骏组。这些益处在不同性别和年龄的亚组中是一致的。根据个体的SCORAD测量，在所有亚组中都一致观察到皮肤发红的减少。当专注于特应性皮炎时，Miyarisan使用者也显示出较低的不良皮肤结果风险，类似于湿疹或皮炎患者。结论：在成人中使用miyarisan可以减少湿疹或皮炎的复发，在性别和年龄组中都有一致的益处。这些发现也见于特应性皮炎患者。
{"title":"The effect of probiotic (Clostridium butyricum) on adult patients with atopic dermatitis: a retrospective cohort study from TriNetX","authors":"Kuo-Hsiung Shu , Yun-Chien Tsai , Cheng-Hsu Chen , Shang-Feng Tsai","doi":"10.1016/j.hnm.2025.200332","DOIUrl":"10.1016/j.hnm.2025.200332","url":null,"abstract":"<div><h3>Background</h3><div>Previous research on probiotics has mainly focused on eczema in infants and pregnant women, with limited benefits observed in adults. Miyarisan, a probiotic known for supporting gut barrier function, has not been extensively studied for its effects on eczema in adult populations.</div></div><div><h3>Methods</h3><div>We used the TriNetX global network (2014–2024) to compare Miyarisan users with non-users among eczema or dermatitis patients. Propensity score matching (PSM) reduced bias, and hazard ratios (HRs) with 95 % confidence intervals (CIs) and Kaplan-Meier curves assessed skin outcomes based on the SCORAD index. Subgroup analyses explored variations by sex, age, and medication refill frequency, with a sensitivity analysis focusing on atopic dermatitis patients.</div></div><div><h3>Results</h3><div>Following 1:1 PS M, the study analyzed 1600 cases in each group (Miyarisan users and non-users) without difference between baseline variables. The incidence of itching (HR = 0.372, 95 % CI: 0.287–0.481, p < 0.001), redness (HR = 0.065, 95 % CI: 0.040–0.108, p < 0.001), dryness (HR = 0.358, 95 % CI: 0.285–0.449, p < 0.001), swelling (HR = 0.164, 95 % CI: 0.101–0.265, p < 0.001), scratching (HR = 0.426, 95 % CI: 0.296–0.612, p < 0.001), and thickening (HR = 0.325, 95 % CI: 0.225–0.467, p < 0.001) were significantly lower in the Miyarisan group compared to the non-Miyarisan group. These benefits were consistent across different gender and age subgroups. According to individual SCORAD measures, reduced skin redness was consistently observed across all subgroups. When focusing on atopic dermatitis, Miyarisan users also showed a lower risk of adverse skin outcomes, similar to patients with eczema or dermatitis.</div></div><div><h3>Conclusion</h3><div>Miyarisan use in adults may reduce the recurrence of eczema or dermatitis, with consistent benefits across both sex and age groups. These findings are also observed in patients with atopic dermatitis.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200332"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-05-03DOI: 10.1016/j.hnm.2025.200319
Samira Movahed , Farid Zayeri , Behnood Abbasi
Objective
Given that the lacto-vegetarian dietary score (LVDS), has not been previously examined in relation to formation of calcium oxalate (CaOx) kidney stones (KS), we chose to explore this potential association.
Methods
This case-control investigation involved 620 individuals, comprising 310 newly diagnosed patients with CaOx stones and 310 control subjects. Dietary consumption was evaluated through a validated 147-item food frequency questionnaire covering the previous year. The relationship between LVDs and KS was analyzed utilizing multivariable logistic regression.
Results
The results of the current study demonstrated that controls had higher mean LVDs (36.62 ± 4.74 vs 35.55 ± 5.27, P = 0.008), intake of fruits (214.31 ± 116.04 vs 196.58 ± 100.94, P = 0.043), vegetables (322.98 ± 193.89 vs 275.10 ± 154.41, P < 0.001), dairy (407.09 ± 224.24 vs 349.71 ± 222.93, P = 0.001) and olive oil (13.12 ± 2.82 vs 12.47 ± 2.09, P = 0.001) than those with CaOx KS. The univariate logistic regression results revealed that each unit increase in LVD score decreases the odds of having KS by 4.2 % (OR = 0.958, P = 0.009). After adjusting for age and BMI, the estimated OR was 0.95 for men (P = 0.013). Participants in the first tertile of LVDs had about 52 % higher odds of having KS than those in the third tertile (OR = 1.52, P = 0.04). However, a significant difference was found in male participants in the first and third tertiles of LVDs regarding the odds of having KS after adjusting for age and BMI (adjusted OR = 1.87, P = 0.02). The similar difference was not significant in female participants (OR = 0.49, P = 0.15).
Conclusion
Increasing in the LVD score is associated with a decrease in the likelihood of developing KS overall, with a more pronounced reduction in men.
考虑到乳素饮食评分（LVDS）与草酸钙（CaOx）肾结石（KS）形成的关系，我们选择探索这种潜在的联系。方法本研究共纳入620例患者，其中新诊断的CaOx结石310例，对照组310例。通过一份涵盖前一年的经过验证的147项食物频率问卷来评估饮食消费。利用多变量logistic回归分析LVDs与KS之间的关系。结果对照组LVDs（36.62±4.74 vs 35.55±5.27,P = 0.008）、水果摄入量（214.31±116.04 vs 196.58±100.94,P = 0.043）、蔬菜摄入量(322.98±193.89 vs 275.10±154.41,P <；0.001)、乳制品（407.09±224.24 vs 349.71±222.93,P = 0.001）和橄榄油（13.12±2.82 vs 12.47±2.09,P = 0.001）均高于CaOx KS组。单因素logistic回归结果显示，LVD评分每增加一个单位，发生KS的几率降低4.2% （OR = 0.958, P = 0.009）。在调整年龄和BMI后，男性的估计OR为0.95 （P = 0.013）。LVDs第一分位的参与者发生KS的几率比第三分位的参与者高52% （OR = 1.52, P = 0.04）。然而，在调整年龄和BMI后，LVDs的第一和第三十分位男性受试者发生KS的几率有显著差异（调整OR = 1.87, P = 0.02）。类似的差异在女性参与者中不显著（OR = 0.49, P = 0.15）。结论：LVD评分的增加与总体上发生KS的可能性降低有关，其中男性的降低更为明显。
{"title":"The lacto-vegetarian dietary score and kidney stones are likely to be inversely associated in men but not in women: A case-control study","authors":"Samira Movahed , Farid Zayeri , Behnood Abbasi","doi":"10.1016/j.hnm.2025.200319","DOIUrl":"10.1016/j.hnm.2025.200319","url":null,"abstract":"<div><h3>Objective</h3><div>Given that the lacto-vegetarian dietary score (LVDS), has not been previously examined in relation to formation of calcium oxalate (CaOx) kidney stones (KS), we chose to explore this potential association.</div></div><div><h3>Methods</h3><div>This case-control investigation involved 620 individuals, comprising 310 newly diagnosed patients with CaOx stones and 310 control subjects. Dietary consumption was evaluated through a validated 147-item food frequency questionnaire covering the previous year. The relationship between LVDs and KS was analyzed utilizing multivariable logistic regression.</div></div><div><h3>Results</h3><div>The results of the current study demonstrated that controls had higher mean LVDs (36.62 ± 4.74 vs 35.55 ± 5.27, P = 0.008), intake of fruits (214.31 ± 116.04 vs 196.58 ± 100.94, P = 0.043), vegetables (322.98 ± 193.89 vs 275.10 ± 154.41, P < 0.001), dairy (407.09 ± 224.24 vs 349.71 ± 222.93, P = 0.001) and olive oil (13.12 ± 2.82 vs 12.47 ± 2.09, P = 0.001) than those with CaOx KS. The univariate logistic regression results revealed that each unit increase in LVD score decreases the odds of having KS by 4.2 % (OR = 0.958, P = 0.009). After adjusting for age and BMI, the estimated OR was 0.95 for men (P = 0.013). Participants in the first tertile of LVDs had about 52 % higher odds of having KS than those in the third tertile (OR = 1.52, P = 0.04). However, a significant difference was found in male participants in the first and third tertiles of LVDs regarding the odds of having KS after adjusting for age and BMI (adjusted OR = 1.87, P = 0.02). The similar difference was not significant in female participants (OR = 0.49, P = 0.15).</div></div><div><h3>Conclusion</h3><div>Increasing in the LVD score is associated with a decrease in the likelihood of developing KS overall, with a more pronounced reduction in men.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200319"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-06-19DOI: 10.1016/j.hnm.2025.200328
Tao Yu , Shu Zhang , Ryota Wakayama , Tomohito Horimoto , Chikako Tange , Yukiko Nishita , Rei Otsuka
Background
The serum 25-hydroxyvitamin D (25OHVD) insufficiency is a recognized public health nutrition concern globally. The relationship between dietary factors and serum 25OHVD levels remains unclear in the Japanese population.
Objective
This study aimed to evaluate diet quality using the Meiji Nutritional Profiling System (Meiji NPS) and investigated its cross-sectional association with serum 25OHVD levels in Japanese middle-aged and older adults.
Methods
Data were analyzed from 1272 middle-aged adults and 873 older adults participating in the National Institute for Longevity Sciences - Longitudinal Study of Aging in Japan. Participants with complete dietary records and serum 25OHVD measurements were included. Diet quality was assessed using the Meiji NPS, and a dietary index was calculated for each individual. Associations between diet quality and serum 25OHVD levels were examined using general linear model adjusted for various covariates.
Results
The median age, dietary index, and prevalence of serum 25OHVD insufficiency (<30 ng/ml) were 53 years, 10.1 points, and 74.2 % in adults, and 73.0 years, 12.0 points, and 60.5 % in older adults, respectively. Higher dietary indices were positively associated with serum 25OHVD levels in both adults (partial regression coefficient 0.11; 95 % confidence interval: 0.04–0.18), and older adults (0.17, 0.07–0.26).
Conclusions
This study suggests a positive association between diet quality, as evaluated by the Meiji NPS, and serum 25OHVD levels in middle-aged and older adults.
{"title":"Association between diet quality evaluated using the Meiji nutritional profiling system and serum 25-hydroxyvitamin D levels in Japanese adults and older adults: A cross-sectional study from the NILS-LSA","authors":"Tao Yu , Shu Zhang , Ryota Wakayama , Tomohito Horimoto , Chikako Tange , Yukiko Nishita , Rei Otsuka","doi":"10.1016/j.hnm.2025.200328","DOIUrl":"10.1016/j.hnm.2025.200328","url":null,"abstract":"<div><h3>Background</h3><div>The serum 25-hydroxyvitamin D (25OHVD) insufficiency is a recognized public health nutrition concern globally. The relationship between dietary factors and serum 25OHVD levels remains unclear in the Japanese population.</div></div><div><h3>Objective</h3><div>This study aimed to evaluate diet quality using the Meiji Nutritional Profiling System (Meiji NPS) and investigated its cross-sectional association with serum 25OHVD levels in Japanese middle-aged and older adults.</div></div><div><h3>Methods</h3><div>Data were analyzed from 1272 middle-aged adults and 873 older adults participating in the National Institute for Longevity Sciences - Longitudinal Study of Aging in Japan. Participants with complete dietary records and serum 25OHVD measurements were included. Diet quality was assessed using the Meiji NPS, and a dietary index was calculated for each individual. Associations between diet quality and serum 25OHVD levels were examined using general linear model adjusted for various covariates.</div></div><div><h3>Results</h3><div>The median age, dietary index, and prevalence of serum 25OHVD insufficiency (<30 ng/ml) were 53 years, 10.1 points, and 74.2 % in adults, and 73.0 years, 12.0 points, and 60.5 % in older adults, respectively. Higher dietary indices were positively associated with serum 25OHVD levels in both adults (partial regression coefficient 0.11; 95 % confidence interval: 0.04–0.18), and older adults (0.17, 0.07–0.26).</div></div><div><h3>Conclusions</h3><div>This study suggests a positive association between diet quality, as evaluated by the Meiji NPS, and serum 25OHVD levels in middle-aged and older adults.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200328"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144518058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L-arginine is an amino acid found in most protein-rich foods, such as fish, red meat, poultry, soy, whole grains, beans and dairy products. Thus, it helps the body in building proteins.
Objectives
To find the effect of L-arginine in the improvement of lipid profile, liver enzymes, and blood pressure using various study outcomes.
Materials and methods
We searched all the related studies that probed into the association between L-arginine and serum lipid levels, liver enzymes, and blood pressure on PubMed, Web of Science, EMBASE, and Cochrane Library database up to May 20, 2024. The quality of the included studies was evaluated using the Cochrane quality assessment tool for Randomized Control Trials (RCT). MeSH was used to harmonize the keywords throughout the search process. All the statistical analyses of this meta-analysis were performed using the STATA, version 15 software.
Results
A total of 17 studies were included in the final review, a total of 531 screened studies. L-arginine at a dose rate of ≥8.0 g/day significantly improved the lipid profile by reducing total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) levels. Additionally, L-arginine at a dose rate of ≥8.0 g/day significantly reduced both systolic and diastolic blood pressure. However, L-arginine non-significantly reduced aspartate transferase (AST) and alanine transaminase (ALT) at that dose. Finally, the results of random-effects meta-regression analyses examining the association between the dose of L-arginine and the effect size of various health indicators showed a non-significant effect. Conclusions: L-arginine potentially improved the lipid profile, blood pressure and liver enzymes among studied individuals worldwide.
背景：精氨酸是一种氨基酸，存在于大多数富含蛋白质的食物中，如鱼、红肉、家禽、大豆、全谷物、豆类和乳制品。因此，它可以帮助身体构建蛋白质。目的探讨l -精氨酸对血脂、肝酶和血压的改善作用。材料和方法我们检索了PubMed、Web of Science、EMBASE和Cochrane图书馆数据库中截至2024年5月20日所有关于l -精氨酸与血脂水平、肝酶和血压之间关系的相关研究。采用Cochrane随机对照试验质量评价工具（RCT）对纳入研究的质量进行评价。在整个搜索过程中，使用MeSH来协调关键词。本meta分析的所有统计分析均使用STATA， version 15软件进行。结果最终纳入17项研究，共筛选531项研究。剂量率≥8.0 g/天的l -精氨酸通过降低总胆固醇（TC）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）和甘油三酯（TG）水平显著改善了脂质谱。此外，l -精氨酸≥8.0 g/天的剂量率显著降低收缩压和舒张压。然而，在该剂量下，l -精氨酸没有显著降低天冬氨酸转移酶（AST）和丙氨酸转氨酶（ALT）。最后，随机效应meta回归分析的结果显示，l -精氨酸剂量与各种健康指标的效应大小之间的关系没有显著影响。结论：l -精氨酸有改善血脂、血压和肝酶的潜力。
{"title":"The role of L-Arginine in improvement of lipid profile, liver enzymes, and blood pressure: A systematic review of randomized control trial studies","authors":"Hawal Lateef Fateh , Maryam Sharifi Najafabadi , Jalal Moludi , Dyari Hassan Ahmed , Heshu Sulaiman Rahman , Hassan Mohammad Tawfeeq","doi":"10.1016/j.hnm.2025.200310","DOIUrl":"10.1016/j.hnm.2025.200310","url":null,"abstract":"<div><h3>Background</h3><div>L-arginine is an amino acid found in most protein-rich foods, such as fish, red meat, poultry, soy, whole grains, beans and dairy products. Thus, it helps the body in building proteins.</div></div><div><h3>Objectives</h3><div>To find the effect of L-arginine in the improvement of lipid profile, liver enzymes, and blood pressure using various study outcomes.</div></div><div><h3>Materials and methods</h3><div>We searched all the related studies that probed into the association between L-arginine and serum lipid levels, liver enzymes, and blood pressure on PubMed, Web of Science, EMBASE, and Cochrane Library database up to May 20, 2024. The quality of the included studies was evaluated using the Cochrane quality assessment tool for Randomized Control Trials (RCT). MeSH was used to harmonize the keywords throughout the search process. All the statistical analyses of this meta-analysis were performed using the STATA, version 15 software.</div></div><div><h3>Results</h3><div>A total of 17 studies were included in the final review, a total of 531 screened studies. L-arginine at a dose rate of ≥8.0 g/day significantly improved the lipid profile by reducing total cholesterol (TC), low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) levels. Additionally, L-arginine at a dose rate of ≥8.0 g/day significantly reduced both systolic and diastolic blood pressure. However, L-arginine non-significantly reduced aspartate transferase (AST) and alanine transaminase (ALT) at that dose. Finally, the results of random-effects meta-regression analyses examining the association between the dose of L-arginine and the effect size of various health indicators showed a non-significant effect. <strong>Conclusions</strong>: L-arginine potentially improved the lipid profile, blood pressure and liver enzymes among studied individuals worldwide.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200310"},"PeriodicalIF":1.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-01Epub Date: 2025-06-02DOI: 10.1016/j.hnm.2025.200326
Chongyang She , Wenying Fan , Yunyun Li , Hong Lu , Mengxuan Zou
Objectives
This study investigates the association between daily nutrient intake, including antioxidants, minerals, and other essential nutrients, and cataract development in a diabetic Chinese population.
Methods
A total of 398 patients with type 2 diabetes from an urban Chinese community were recruited between January 2010 and January 2011. Participants underwent standardized evaluation, including questionnaires, ocular and anthropometric examinations, and laboratory tests. Dietary data were collected by 3-day food records. Cataract including nuclear, cortical, and posterior subcapsular cataracts (PSC), were graded according to Lens Opacities Classification System III. Multivariable logistic regressions were conducted to analyze associations between each dietary nutrient and cataract development, adjusting for social-demographic factors, lifestyle, age at onset of diabetes, and diabetes-related biomarkers in different models.
Results
Of the participants, 230 were in the cataract group, while 168 in the non-cataract group. The mean age was higher in the cataract group (68.3 ± 6.4 years) compared to non-cataract group (59.4 ± 9.4 years, P < 0.001). PSC were more severe in patients with diabetic retinopathy (P = 0.020). Dietary vitamin C was positively associated with nuclear cataracts (P < 0.05 across all models). Riboflavin (P = 0.023) and phosphorus (P = 0.026) were associated with cortical cataracts, while phosphorus (P = 0.043) and folic acid (P = 0.044) were associated with PSC cataracts. No associations were found for other nutrients.
Conclusions
Dietary vitamin C was associated with an increased risk of nuclear cataracts, while riboflavin and phosphorus were linked to cortical cataracts, phosphorus and folic acid were associated with PSC cataract. The severity of cataracts was more pronounced in patients with diabetic retinopathy.
{"title":"Association between nutrient intake and cataracts in a Chinese type 2 diabetic population","authors":"Chongyang She , Wenying Fan , Yunyun Li , Hong Lu , Mengxuan Zou","doi":"10.1016/j.hnm.2025.200326","DOIUrl":"10.1016/j.hnm.2025.200326","url":null,"abstract":"<div><h3>Objectives</h3><div>This study investigates the association between daily nutrient intake, including antioxidants, minerals, and other essential nutrients, and cataract development in a diabetic Chinese population.</div></div><div><h3>Methods</h3><div>A total of 398 patients with type 2 diabetes from an urban Chinese community were recruited between January 2010 and January 2011. Participants underwent standardized evaluation, including questionnaires, ocular and anthropometric examinations, and laboratory tests. Dietary data were collected by 3-day food records. Cataract including nuclear, cortical, and posterior subcapsular cataracts (PSC), were graded according to Lens Opacities Classification System III. Multivariable logistic regressions were conducted to analyze associations between each dietary nutrient and cataract development, adjusting for social-demographic factors, lifestyle, age at onset of diabetes, and diabetes-related biomarkers in different models.</div></div><div><h3>Results</h3><div>Of the participants, 230 were in the cataract group, while 168 in the non-cataract group. The mean age was higher in the cataract group (68.3 ± 6.4 years) compared to non-cataract group (59.4 ± 9.4 years, <em>P</em> < 0.001). PSC were more severe in patients with diabetic retinopathy (<em>P</em> = 0.020). Dietary vitamin C was positively associated with nuclear cataracts (<em>P</em> < 0.05 across all models). Riboflavin (<em>P</em> = 0.023) and phosphorus (<em>P</em> = 0.026) were associated with cortical cataracts, while phosphorus (<em>P</em> = 0.043) and folic acid (<em>P</em> = 0.044) were associated with PSC cataracts. No associations were found for other nutrients.</div></div><div><h3>Conclusions</h3><div>Dietary vitamin C was associated with an increased risk of nuclear cataracts, while riboflavin and phosphorus were linked to cortical cataracts, phosphorus and folic acid were associated with PSC cataract. The severity of cataracts was more pronounced in patients with diabetic retinopathy.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200326"},"PeriodicalIF":1.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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