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Analysis of dietary amino acid and fatty acid intake profiles of US adults: NHANES 2017–March 2020 Pre-pandemic 美国成年人膳食氨基酸和脂肪酸摄入量分析:NHANES 2017-March 2020
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-06-13 DOI: 10.1016/j.hnm.2025.200329
Miyu Kenzaka , Haruka Nishiyama , Miyuki Imafuku , Sae Nakao , Sari Natsume , Chika Oue , Hisami Yamanaka-Okumura
Recently, the digitalization of data science in nutrition has highlighted the need for comprehensive dietary databases to interpret dietary habits accurately. Previous studies have elucidated detailed profiles of amino acids (AAs) and fatty acids (FAs) in the Japanese diet beyond the general categories of proteins and lipids. This study aimed to profile the intake of AAs and FAs in the United States (U.S.) population, focusing on the quantity of these nutrients. By linking the USDA National Nutrient Database for Standard Reference with the National Health and Nutrition Examination Survey 2017–March 2020 data, we estimated the average dietary intake of 18 AAs and 19 FAs in the U.S. population, expressed in mg/1000 kcal and calculated their respective contributions. Among the 18 AAs, glutamic acid, aspartic acid, and leucine were the most consumed, accounting for 19.8 %, 9.1 %, and 8.1 % of the total intake, respectively. Among the 19 FAs, 18:1 constituted the most significant proportion at 36.5 %, followed by 18:2 at 23.3 % and 16:0 at 20.1 %. Although the intake contribution profiles of AA were similar across different food groups, those of FA varied significantly. Overall, we successfully developed a database showing the average intake of AA and FA in the U.S. population rather than focusing solely on proteins and lipids. This database provides a foundation for accurately understanding and interpreting dietary habits in the U.S. population and suggests its potential use as a reference for future international dietary comparisons.
最近,营养数据科学的数字化凸显了对全面的饮食数据库的需求,以准确地解释饮食习惯。以前的研究已经阐明了日本饮食中蛋白质和脂类之外的氨基酸(aa)和脂肪酸(FAs)的详细概况。本研究旨在分析美国人群中aa和FAs的摄入量,重点关注这些营养素的数量。通过将美国农业部国家营养标准参考数据库与2017年3月至2020年3月的国家健康与营养检查调查数据联系起来,我们估计了美国人群中18种aa和19种FAs的平均膳食摄入量,以mg/1000 kcal表示,并计算了它们各自的贡献。在18种氨基酸中,谷氨酸、天冬氨酸和亮氨酸的摄入量最多,分别占总摄入量的19.8%、9.1%和8.1%。在19个FAs中,18:1的比例最大,为36.5%,其次是18:2(23.3%)和16:0(20.1%)。虽然不同食物组AA的摄入贡献谱相似,但FA的摄入贡献谱差异显著。总的来说,我们成功地开发了一个数据库,显示了美国人口中AA和FA的平均摄入量,而不仅仅是蛋白质和脂质。该数据库为准确理解和解释美国人口的饮食习惯提供了基础,并建议将其作为未来国际饮食比较的参考。
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引用次数: 0
Food insecurity and health behaviors in a disaster-affected population: A case study of Tacloban, Philippines 受灾人口的粮食不安全和健康行为:以菲律宾塔克洛班为例
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-06-03 DOI: 10.1016/j.hnm.2025.200327
Gashaw Enbiyale Kasse , Abdo Megra Geda , Aregash Wendimu Tumebo , Elvis Akem Tambe , Abraham Belete Temesgen , Mulusew Tesfaye Yitie , Tadesse Mihiret Yimam , Samuel Atalay Shiferaw

Background

Food insecurity is a widespread issue that poses a major global challenge with far-reaching impacts.

Objective

Investigate the relationship between food insecurity and health behaviors among the population of Tacloban, Philippines, affected by Typhoon Haiyan in 2013.

Methods

This study employed a cross-sectional design, surveying 226 households between April 2022 and June 2023. Households were selected using a systematic random sampling technique to ensure representative coverage. To evaluate food insecurity, we utilized the Food Insecurity Experience Scale-a robust tool that captures the degree to which individuals or households face challenges in accessing sufficient and nutritious food due to economic and social constraints. In addition, we explored a variety of health-related behaviors among participants, including the use of traditional healing practices, engagement in physical activity, sleep patterns and duration, dietary habits, medication adherence, as well as alcohol and tobacco use. The relationships between food insecurity and these health behaviors were rigorously examined using multiple logistic regression analysis, providing valuable insights into the interplay between access to food and lifestyle choices within the community.

Results

The results showed that 94 % of households experienced food insecurity, with 27 % severely, 52 % moderately, and 15 % mildly food insecure. The analysis revealed significant associations between food insecurity and several health behaviors. Food insecurity was found to be significantly associated with lower medication adherence, greater use of traditional healers, poorer dietary habits, and sleeping problems. However, no significant associations were found between food insecurity and smoking behavior, physical activities, or alcohol consumption.

Conclusion

Based on these findings, the study concluded that food insecurity negatively impacts health behaviors. Therefore, the authors suggested that improving food security in households could potentially lead to improvements in health behaviors.
粮食不安全是一个广泛存在的问题,对全球构成重大挑战,影响深远。目的探讨2013年菲律宾塔克洛班市受台风“海燕”影响人群食物不安全与健康行为的关系。方法本研究采用横断面设计,在2022年4月至2023年6月期间调查了226户家庭。采用系统随机抽样技术选择住户,以确保有代表性的覆盖率。为了评估粮食不安全状况,我们使用了粮食不安全体验量表,这是一种强大的工具,可以衡量个人或家庭因经济和社会限制而在获取充足和有营养的食物方面面临挑战的程度。此外,我们还探讨了参与者之间的各种健康相关行为,包括使用传统治疗方法、参与体育活动、睡眠模式和持续时间、饮食习惯、药物依从性以及酒精和烟草使用。使用多元逻辑回归分析严格检查了粮食不安全与这些健康行为之间的关系,为社区内获得食物与生活方式选择之间的相互作用提供了有价值的见解。结果94%的家庭经历粮食不安全,其中27%为严重粮食不安全,52%为中度粮食不安全,15%为轻度粮食不安全。分析显示,粮食不安全与几种健康行为之间存在显著关联。研究发现,食物不安全与较低的药物依从性、更多地使用传统治疗师、较差的饮食习惯和睡眠问题显著相关。然而,没有发现食物不安全与吸烟行为、体育活动或饮酒之间存在显著关联。基于这些发现,该研究得出结论,粮食不安全对健康行为产生负面影响。因此,作者建议,改善家庭食品安全可能会导致健康行为的改善。
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引用次数: 0
Diagnostic potential of waist–triglyceride index, triglyceride–glucose index and related indices for the detection of metabolic syndrome in Nepali adults: A cross-sectional study 腰-甘油三酯指数、甘油三酯-葡萄糖指数及相关指数在尼泊尔成年人代谢综合征检测中的诊断潜力:一项横断面研究
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-06-02 DOI: 10.1016/j.hnm.2025.200324
Daya Ram Pokharel , Abhishek Maskey , Ramchandra Kafle , Goma Kathayat , Binod Manandhar , Krishna Das Manandhar
Metabolic Syndrome (MetS) is a major public health concern associated with elevated risk of cardiometabolic diseases. Conventional diagnostic criteria for MetS require multiple clinical and biochemical measurements, limiting feasibility in resource-constrained settings. Novel anthropo-metabolic indices offer a simplified, surrogate approach for risk prediction and stratification. This study aimed to evaluate the diagnostic performance of the triglyceride-glucose (TyG) index, waist-triglyceride index (WTI), and their derivatives TyG-waist circumference (TyG-WC), TyG-waist-to-height ratio (TyG-WHtR), and TyG-body mass index (TyG-BMI) for detecting the risk of MetS in Nepali adults.
A cross-sectional study was conducted among 1116 adults (424 females, 692 males) recruited from the premises of Manipal Teaching Hospital, Pokhara, Nepal. Baseline sociodemographic, anthropometric, and biochemical data were collected. MetS was defined using National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Indices were calculated using standard formulae and their associations with MetS were examined using Spearman's correlation, multivariable logistic regression, and receiver operating characteristic (ROC) curve analyses.
All indices demonstrated significant diagnostic capability for the detection of MetS (p < 0.001). The TyG index showed the highest overall accuracy, with area under the curve (AUC) of 0.920 in females and 0.874 in males. At optimal sex-specific cutoffs (≥8.66 for females, ≥8.87 for males), TyG demonstrated excellent sensitivity (female: 88.40 %, male: 85.55 %) and specificity (female: 88.00 %, male: 81.20 %). WTI and TyG-WC showed strong performance in identifying hypertriglyceridemia and central obesity, respectively. Logistic regression confirmed the TyG index as the strongest independent predictor of MetS (adjusted odds ratio (AOR): females = 58.59, males = 30.94, p < 0.001). Predictive accuracy was lower for hypertension and low high density lipoprotein cholesterol (HDL-C). Comparative AUC analysis revealed greater index variability among females than males.
The TyG, TyG-WC and WTI are found to be robust, gender-specific tools for diagnosis of MetS and its components in Nepali adults. Their simplicity, affordability and high diagnostic accuracy support their integration into large-scale MetS screening in resource-limited settings. Sex-specific cutoffs enhance the precision of risk assessments, emphasizing the need for tailored screening strategies.
代谢综合征(MetS)是一个主要的公共卫生问题,与心脏代谢疾病的风险升高有关。传统的met诊断标准需要多种临床和生化测量,这限制了在资源有限的情况下的可行性。新的人类代谢指标为风险预测和分层提供了一种简化的替代方法。本研究旨在评估甘油三酯-葡萄糖(TyG)指数、腰围-甘油三酯指数(WTI)及其衍生物TyG-腰围(TyG- wc)、TyG-腰高比(TyG- whtr)和TyG-体重指数(TyG- bmi)在尼泊尔成年人met风险检测中的诊断性能。对从尼泊尔博卡拉马尼帕尔教学医院招募的1116名成年人(424名女性,692名男性)进行了横断面研究。收集基线社会人口学、人体测量学和生化数据。MetS是根据国家胆固醇教育计划成人治疗小组III (NCEP ATP III)标准定义的。使用标准公式计算指标,并使用Spearman相关、多变量logistic回归和受试者工作特征(ROC)曲线分析检验其与MetS的相关性。所有指标对met的检测均显示出显著的诊断能力(p <;0.001)。TyG指数的总体准确度最高,女性的曲线下面积(AUC)为0.920,男性为0.874。在最佳性别特异性截止点(女性≥8.66,男性≥8.87),TyG表现出优异的敏感性(女性:88.40%,男性:85.55%)和特异性(女性:88.00%,男性:81.20%)。WTI和TyG-WC分别在识别高甘油三酯血症和中心性肥胖方面表现出很强的性能。Logistic回归证实TyG指数是MetS最强的独立预测因子(调整优势比(AOR)):女性= 58.59,男性= 30.94,p <;0.001)。高血压和低高密度脂蛋白胆固醇(HDL-C)的预测准确性较低。对比AUC分析显示,女性的指数变异性大于男性。发现TyG、TyG- wc和WTI是尼泊尔成年人诊断met及其组成部分的强大的、针对性别的工具。它们的简单性、可负担性和高诊断准确性支持将其整合到资源有限的环境中进行大规模met筛查。按性别划分的临界值提高了风险评估的准确性,强调了量身定制筛查策略的必要性。
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引用次数: 0
Association between nutrient intake and cataracts in a Chinese type 2 diabetic population 中国2型糖尿病人群中营养摄入与白内障的关系
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-06-02 DOI: 10.1016/j.hnm.2025.200326
Chongyang She , Wenying Fan , Yunyun Li , Hong Lu , Mengxuan Zou

Objectives

This study investigates the association between daily nutrient intake, including antioxidants, minerals, and other essential nutrients, and cataract development in a diabetic Chinese population.

Methods

A total of 398 patients with type 2 diabetes from an urban Chinese community were recruited between January 2010 and January 2011. Participants underwent standardized evaluation, including questionnaires, ocular and anthropometric examinations, and laboratory tests. Dietary data were collected by 3-day food records. Cataract including nuclear, cortical, and posterior subcapsular cataracts (PSC), were graded according to Lens Opacities Classification System III. Multivariable logistic regressions were conducted to analyze associations between each dietary nutrient and cataract development, adjusting for social-demographic factors, lifestyle, age at onset of diabetes, and diabetes-related biomarkers in different models.

Results

Of the participants, 230 were in the cataract group, while 168 in the non-cataract group. The mean age was higher in the cataract group (68.3 ± 6.4 years) compared to non-cataract group (59.4 ± 9.4 years, P < 0.001). PSC were more severe in patients with diabetic retinopathy (P = 0.020). Dietary vitamin C was positively associated with nuclear cataracts (P < 0.05 across all models). Riboflavin (P = 0.023) and phosphorus (P = 0.026) were associated with cortical cataracts, while phosphorus (P = 0.043) and folic acid (P = 0.044) were associated with PSC cataracts. No associations were found for other nutrients.

Conclusions

Dietary vitamin C was associated with an increased risk of nuclear cataracts, while riboflavin and phosphorus were linked to cortical cataracts, phosphorus and folic acid were associated with PSC cataract. The severity of cataracts was more pronounced in patients with diabetic retinopathy.
目的探讨中国糖尿病人群每日营养摄入(包括抗氧化剂、矿物质和其他必需营养素)与白内障发展之间的关系。方法2010年1月至2011年1月,从中国城市社区招募398例2型糖尿病患者。参与者接受了标准化评估,包括问卷调查、眼部和人体测量检查以及实验室测试。采用3 d饮食记录法收集饮食数据。根据晶状体混浊分级系统III对核性、皮质性和后囊下性白内障(PSC)进行分级。采用多变量logistic回归分析了每种膳食营养素与白内障发展之间的关系,并在不同模型中调整了社会人口因素、生活方式、糖尿病发病年龄和糖尿病相关生物标志物。结果白内障组230例,非白内障组168例。白内障组平均年龄(68.3±6.4岁)高于非白内障组(59.4±9.4岁),P <;0.001)。糖尿病视网膜病变患者PSC加重(P = 0.020)。膳食维生素C与核性白内障呈正相关(P <;所有模型均为0.05)。核黄素(P = 0.023)和磷(P = 0.026)与皮质性白内障相关,磷(P = 0.043)和叶酸(P = 0.044)与PSC型白内障相关。其他营养物质没有发现关联。结论膳食维生素C与核性白内障风险增加有关,核黄素和磷与皮质性白内障风险增加有关,磷和叶酸与PSC白内障风险增加有关。糖尿病视网膜病变患者白内障的严重程度更为明显。
{"title":"Association between nutrient intake and cataracts in a Chinese type 2 diabetic population","authors":"Chongyang She ,&nbsp;Wenying Fan ,&nbsp;Yunyun Li ,&nbsp;Hong Lu ,&nbsp;Mengxuan Zou","doi":"10.1016/j.hnm.2025.200326","DOIUrl":"10.1016/j.hnm.2025.200326","url":null,"abstract":"<div><h3>Objectives</h3><div>This study investigates the association between daily nutrient intake, including antioxidants, minerals, and other essential nutrients, and cataract development in a diabetic Chinese population.</div></div><div><h3>Methods</h3><div>A total of 398 patients with type 2 diabetes from an urban Chinese community were recruited between January 2010 and January 2011. Participants underwent standardized evaluation, including questionnaires, ocular and anthropometric examinations, and laboratory tests. Dietary data were collected by 3-day food records. Cataract including nuclear, cortical, and posterior subcapsular cataracts (PSC), were graded according to Lens Opacities Classification System III. Multivariable logistic regressions were conducted to analyze associations between each dietary nutrient and cataract development, adjusting for social-demographic factors, lifestyle, age at onset of diabetes, and diabetes-related biomarkers in different models.</div></div><div><h3>Results</h3><div>Of the participants, 230 were in the cataract group, while 168 in the non-cataract group. The mean age was higher in the cataract group (68.3 ± 6.4 years) compared to non-cataract group (59.4 ± 9.4 years, <em>P</em> &lt; 0.001). PSC were more severe in patients with diabetic retinopathy (<em>P</em> = 0.020). Dietary vitamin C was positively associated with nuclear cataracts (<em>P</em> &lt; 0.05 across all models). Riboflavin (<em>P</em> = 0.023) and phosphorus (<em>P</em> = 0.026) were associated with cortical cataracts, while phosphorus (<em>P</em> = 0.043) and folic acid (<em>P</em> = 0.044) were associated with PSC cataracts. No associations were found for other nutrients.</div></div><div><h3>Conclusions</h3><div>Dietary vitamin C was associated with an increased risk of nuclear cataracts, while riboflavin and phosphorus were linked to cortical cataracts, phosphorus and folic acid were associated with PSC cataract. The severity of cataracts was more pronounced in patients with diabetic retinopathy.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200326"},"PeriodicalIF":1.9,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144261666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The miracle Berry: Unveiling the therapeutic attributes of sea buckthorn – A review 神奇的浆果:揭示沙棘的治疗属性-综述
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-05-08 DOI: 10.1016/j.hnm.2025.200321
Rabiya Zulfiqar , Kainat Fatima , Iahtisham-Ul Haq , Robert Mugabi , Aanchal Sharma , Sarvesh Rustagi , Rattan Singh , Gulzar Ahmad Nayik
Sea buckthorn (Hippophae rhamnoides L.) is a versatile plant renowned for its exceptional nutritional and therapeutic properties. Native to mountainous regions of Asia and Europe, it has been traditionally utilized for its medicinal benefits. Its promising nutritional profile highlighted by significant levels of omega-3 and omega-6 fatty acids, along with omega-7 palmitoleic acid and vitamin C content makes it unique from other plants. Omega-7 palmitoleic acid is an extremely beneficial MUFA that can be crucial in treating different metabolic disorders. Its valuable role in glucose metabolism, skin health, liver functions, inflammatory diseases etc. has been well-reported in the literature. In addition, sea buckthorn has a range of bioactive compounds like antioxidants, polyphenols, flavonoids, sugars, organic acids, vitamins, and minerals that are cardinal for added health benefits. These compounds contribute to the therapeutic potential of sea buckthorn delivering antioxidants, anti-cancer, anti-diabetic, anti-inflammatory, immune boosting and cardio-protective properties. This review sums up the chemical composition, botanical features, uses and therapeutic properties of sea buckthorn to unveil its extraordinary potential and its possible inclusion in routine therapies to improve human health its possible inclusion in routine therapies to improve human health. However, further high-quality studies are needed to firmly establish the clinical efficacy of the plant.
沙棘(Hippophae rhamnoides L.)是一种多功能植物,以其独特的营养和治疗特性而闻名。原产于亚洲和欧洲的山区,传统上因其药用价值而被利用。其富含的omega-3和omega-6脂肪酸,以及omega-7棕榈油酸和维生素C使其在其他植物中独一无二。-7棕榈油酸是一种非常有益的多足脂肪酸,对治疗不同的代谢紊乱至关重要。它在葡萄糖代谢、皮肤健康、肝功能、炎症疾病等方面的重要作用已在文献中得到充分报道。此外,沙棘还含有一系列生物活性化合物,如抗氧化剂、多酚、类黄酮、糖、有机酸、维生素和矿物质,这些都是增加健康益处的主要成分。这些化合物有助于沙棘的治疗潜力,提供抗氧化剂,抗癌,抗糖尿病,抗炎,增强免疫力和保护心脏的特性。本文综述了沙棘的化学成分、植物特征、用途和治疗特性,揭示了沙棘在改善人体健康方面的巨大潜力,以及沙棘在改善人体健康方面的应用前景。然而,需要进一步的高质量研究来确定该植物的临床疗效。
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引用次数: 0
Mindful Eating in the management of eating disorders: A bibliometric study 正念饮食在饮食失调管理中的应用:一项文献计量学研究
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-05-08 DOI: 10.1016/j.hnm.2025.200320
Saltos Atiencia Dayana , Chamba Calva Wilmer
The management of eating disorders (ED) requires a multidisciplinary approach that integrates medical, psychological, and nutritional care. In this context, Mindful Eating (ME) has emerged as a concept gaining increasing attention as a potential adjunctive approach to addressing eating disorders. The aim of this study was to analyze the scientific output related to Mindful Eating in the context of eating disorder management from 2000 to 2025, using a bibliometric analysis. The methodology followed a quantitative, descriptive, and non-experimental approach. The bibliometric study was based on a representative set of scientific articles indexed in the Scopus database. A search string was applied with filters for year, document type, and language to ensure appropriate selection. The analysis was conducted using Bibliometrix (RStudio) for bibliometric measurements and VOSviewer for generating visualizations, graphs, and data mapping. The findings revealed a significant increase in scientific production, with 91 articles published since 2008 and an annual growth rate of 17.39 %. This indicates that Mindful Eating has become a growing research theme, frequently associated with related concepts such as obesity, body weight, bulimia, anorexia, and body image. The study offers a comprehensive overview of the current research landscape, providing a foundation for future investigations into clinical applications and informing the development of hypotheses for targeted interventions.
饮食失调(ED)的管理需要多学科的方法,整合医学,心理和营养护理。在这种背景下,正念饮食(ME)作为一种潜在的辅助方法来解决饮食失调,已经成为一个越来越受到关注的概念。本研究的目的是利用文献计量学分析,分析2000年至2025年饮食失调管理背景下与正念饮食相关的科学产出。研究方法采用定量、描述性和非实验性方法。文献计量学研究基于Scopus数据库中索引的一组具有代表性的科学文章。一个搜索字符串应用了年份、文档类型和语言的过滤器,以确保适当的选择。分析使用Bibliometrix (RStudio)进行文献计量测量,使用VOSviewer生成可视化、图形和数据映射。研究结果显示,科学产出显著增加,自2008年以来发表了91篇论文,年增长率为17.39%。这表明正念饮食已经成为一个日益增长的研究主题,经常与肥胖、体重、贪食症、厌食症和身体形象等相关概念联系在一起。该研究全面概述了当前的研究概况,为未来的临床应用调查奠定了基础,并为有针对性的干预措施提供了假设。
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引用次数: 0
Corrigendum to “Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, Brazil” [Hum. Nutr. Metab. 40 (2025) 200318] “巴西阿拉戈斯州土著居民2岁以下儿童的早期断奶和贫血”的勘误表。减轻。生物工程学报。40 (2025)200318 [j]
IF 1.8 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-05-06 DOI: 10.1016/j.hnm.2025.200322
Valéria Clarisse de Oliveira , Paola Soledad Mosquera , Tamara Rodrigues dos Santos , Haroldo S. Ferreira , Bárbara H. Lourenço , Marly A. Cardoso
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引用次数: 0
The lacto-vegetarian dietary score and kidney stones are likely to be inversely associated in men but not in women: A case-control study 一项病例对照研究显示,乳素饮食评分和肾结石在男性中呈负相关,而在女性中则不然
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-05-03 DOI: 10.1016/j.hnm.2025.200319
Samira Movahed , Farid Zayeri , Behnood Abbasi

Objective

Given that the lacto-vegetarian dietary score (LVDS), has not been previously examined in relation to formation of calcium oxalate (CaOx) kidney stones (KS), we chose to explore this potential association.

Methods

This case-control investigation involved 620 individuals, comprising 310 newly diagnosed patients with CaOx stones and 310 control subjects. Dietary consumption was evaluated through a validated 147-item food frequency questionnaire covering the previous year. The relationship between LVDs and KS was analyzed utilizing multivariable logistic regression.

Results

The results of the current study demonstrated that controls had higher mean LVDs (36.62 ± 4.74 vs 35.55 ± 5.27, P = 0.008), intake of fruits (214.31 ± 116.04 vs 196.58 ± 100.94, P = 0.043), vegetables (322.98 ± 193.89 vs 275.10 ± 154.41, P < 0.001), dairy (407.09 ± 224.24 vs 349.71 ± 222.93, P = 0.001) and olive oil (13.12 ± 2.82 vs 12.47 ± 2.09, P = 0.001) than those with CaOx KS. The univariate logistic regression results revealed that each unit increase in LVD score decreases the odds of having KS by 4.2 % (OR = 0.958, P = 0.009). After adjusting for age and BMI, the estimated OR was 0.95 for men (P = 0.013). Participants in the first tertile of LVDs had about 52 % higher odds of having KS than those in the third tertile (OR = 1.52, P = 0.04). However, a significant difference was found in male participants in the first and third tertiles of LVDs regarding the odds of having KS after adjusting for age and BMI (adjusted OR = 1.87, P = 0.02). The similar difference was not significant in female participants (OR = 0.49, P = 0.15).

Conclusion

Increasing in the LVD score is associated with a decrease in the likelihood of developing KS overall, with a more pronounced reduction in men.
考虑到乳素饮食评分(LVDS)与草酸钙(CaOx)肾结石(KS)形成的关系,我们选择探索这种潜在的联系。方法本研究共纳入620例患者,其中新诊断的CaOx结石310例,对照组310例。通过一份涵盖前一年的经过验证的147项食物频率问卷来评估饮食消费。利用多变量logistic回归分析LVDs与KS之间的关系。结果对照组LVDs(36.62±4.74 vs 35.55±5.27,P = 0.008)、水果摄入量(214.31±116.04 vs 196.58±100.94,P = 0.043)、蔬菜摄入量(322.98±193.89 vs 275.10±154.41,P <;0.001)、乳制品(407.09±224.24 vs 349.71±222.93,P = 0.001)和橄榄油(13.12±2.82 vs 12.47±2.09,P = 0.001)均高于CaOx KS组。单因素logistic回归结果显示,LVD评分每增加一个单位,发生KS的几率降低4.2% (OR = 0.958, P = 0.009)。在调整年龄和BMI后,男性的估计OR为0.95 (P = 0.013)。LVDs第一分位的参与者发生KS的几率比第三分位的参与者高52% (OR = 1.52, P = 0.04)。然而,在调整年龄和BMI后,LVDs的第一和第三十分位男性受试者发生KS的几率有显著差异(调整OR = 1.87, P = 0.02)。类似的差异在女性参与者中不显著(OR = 0.49, P = 0.15)。结论:LVD评分的增加与总体上发生KS的可能性降低有关,其中男性的降低更为明显。
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引用次数: 0
Intermittent fasting and body Composition: Insights from the Iranian National obesity registry (IRNOR) 间歇性禁食与身体组成:来自伊朗国家肥胖登记处(IRNOR)的见解
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-04-28 DOI: 10.1016/j.hnm.2025.200316
Niloufar Abdollahpour , Najmeh Seifi , Mina Nosrati , Habibollah Esmaily , Pardis mohammadyfard , Mahsa Amarlou , Ali Ebrahimi Dabagh , Gordon A. Ferns , Maryam Alinezhad-Namaghi , Majid Ghayour-Mobarhan

Background

The global rise of adiposity has increased interest in novel dietary approaches such as 5:2 intermittent fasting (IF) for health management. This study aimed to assess the impact of a 12-week 5:2 IF on both traditional and novel body composition metrics in individuals with overweight and obesity.

Methods

Data for this12-week longitudinal cohort study was extracted from the electronic database of the Iranian National Obesity Registry (IRNOR). According to data provided by IRNOR, adults with overweight or obesity were compared based on adherence to either 5:2 IF or a daily calorie restriction (CR) program. The 5:2 IF group consumed 500–600 kcal on fasting days and an isocaloric diet on non-fasting days, while the CR group reduced their calorie intake by 500–1000 kcal per day.

Results

A total of 102 participants (mean age 36.75 ± 12.25 years) were included. Over 12 weeks, both groups experienced significant reductions in weight, body circumference, and fat metrics, including visceral fat area (P < 0.05). The IF group, despite a non-significant smaller reduction in total calorie intake, achieved 1 kg greater weight loss than the CR group (−525.33 ± 831.01 vs. −506.23 ± 763.24, P = 0.08). In contrast to the CR group, the 5:2 IF did not show a significant reduction in body cell mass, fat free-mass index, extracellular water-to-total body water, and phase angle over time (P > 0.05).

Conclusions

The 5:2 IF may better preserve cellular structure and hydration balance, achieving clinically significant weight loss. Given its comparable efficacy, it may be a viable alternative. Further studies are required to confirm these findings.
全球肥胖的增加增加了人们对新型饮食方法的兴趣,如5:2间歇性禁食(IF)用于健康管理。本研究旨在评估12周5:2 IF对超重和肥胖个体的传统和新型身体成分指标的影响。方法这项为期12周的纵向队列研究的数据来自伊朗国家肥胖登记处(IRNOR)的电子数据库。根据IRNOR提供的数据,超重或肥胖的成年人根据5:2 IF或每日卡路里限制(CR)计划进行比较。5:2 IF组在禁食日消耗500-600千卡,在非禁食日消耗等热量饮食,而CR组每天减少500-1000千卡的热量摄入。结果共纳入102例患者,平均年龄36.75±12.25岁。在12周内,两组患者的体重、体围和脂肪指标(包括内脏脂肪面积)均显著减少(P <;0.05)。IF组,尽管总热量摄入减少幅度较小,但比CR组多减重1 kg(- 525.33±831.01比- 506.23±763.24,P = 0.08)。与CR组相比,5:2 IF并没有显示出细胞质量、脂肪质量指数、细胞外水/全身总水和相位角随时间的显著降低(P >;0.05)。结论5:2 IF能更好地保持细胞结构和水合平衡,达到临床显著的减肥效果。鉴于其相当的功效,它可能是一个可行的替代方案。需要进一步的研究来证实这些发现。
{"title":"Intermittent fasting and body Composition: Insights from the Iranian National obesity registry (IRNOR)","authors":"Niloufar Abdollahpour ,&nbsp;Najmeh Seifi ,&nbsp;Mina Nosrati ,&nbsp;Habibollah Esmaily ,&nbsp;Pardis mohammadyfard ,&nbsp;Mahsa Amarlou ,&nbsp;Ali Ebrahimi Dabagh ,&nbsp;Gordon A. Ferns ,&nbsp;Maryam Alinezhad-Namaghi ,&nbsp;Majid Ghayour-Mobarhan","doi":"10.1016/j.hnm.2025.200316","DOIUrl":"10.1016/j.hnm.2025.200316","url":null,"abstract":"<div><h3>Background</h3><div>The global rise of adiposity has increased interest in novel dietary approaches such as 5:2 intermittent fasting (IF) for health management. This study aimed to assess the impact of a 12-week 5:2 IF on both traditional and novel body composition metrics in individuals with overweight and obesity.</div></div><div><h3>Methods</h3><div>Data for this12-week longitudinal cohort study was extracted from the electronic database of the Iranian National Obesity Registry (IRNOR). According to data provided by IRNOR, adults with overweight or obesity were compared based on adherence to either 5:2 IF or a daily calorie restriction (CR) program. The 5:2 IF group consumed 500–600 kcal on fasting days and an isocaloric diet on non-fasting days, while the CR group reduced their calorie intake by 500–1000 kcal per day.</div></div><div><h3>Results</h3><div>A total of 102 participants (mean age 36.75 ± 12.25 years) were included. Over 12 weeks, both groups experienced significant reductions in weight, body circumference, and fat metrics, including visceral fat area (P &lt; 0.05). The IF group, despite a non-significant smaller reduction in total calorie intake, achieved 1 kg greater weight loss than the CR group (−525.33 ± 831.01 vs. −506.23 ± 763.24, P = 0.08). In contrast to the CR group, the 5:2 IF did not show a significant reduction in body cell mass, fat free-mass index, extracellular water-to-total body water, and phase angle over time (P &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>The 5:2 IF may better preserve cellular structure and hydration balance, achieving clinically significant weight loss. Given its comparable efficacy, it may be a viable alternative. Further studies are required to confirm these findings.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"41 ","pages":"Article 200316"},"PeriodicalIF":1.9,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, Brazil 巴西阿拉戈斯州土著居民2岁以下儿童的早期断奶和贫血
IF 1.9 Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2025-04-23 DOI: 10.1016/j.hnm.2025.200318
Valéria Clarisse de Oliveira , Paola Soledad Mosquera , Tamara Rodrigues dos Santos , Haroldo S. Ferreira , Bárbara H. Lourenço , Marly A. Cardoso

Objectives

To investigate the frequency of breastfeeding (BF) practices and factors associated with early weaning and anemia in indigenous children under 2 years of age.

Study design

A household cross-sectional study was conducted in 13 indigenous communities in Alagoas state, northeastern Brazil.

Methods

Mothers of eligible children were interviewed to gather socioeconomic, demographic, health, and feeding practice data. Blood samples were collected to assess the hemoglobin concentration (Hb). Multiple Cox, linear, and Poisson regression models were employed to examine the factors associated with weaning and anemia (Hb < 110 g/L in children aged 6 months and older).

Results

Of the 1303 households surveyed, 145 had children under 2 years old. The prevalence of exclusive BF at 6 months was only 19 %. High frequencies of anemia (42.5 %), bottle-feeding (70 %), and pacifier use (31 %) were observed. The use of bottle and pacifier was associated with early weaning. Bottle-feeding was significantly associated with anemia (PR = 2.62; 95 % CI: 1.42–4.84) after adjusting for household wealth index.

Conclusions

BF practices among indigenous children do not meet WHO recommendations. The use of artificial nipples was linked to early weaning, and bottle feeding was associated with anemia after 6 months of age. These findings underscore the urgent need for interventions to promote, protect, and support BF in indigenous people, guiding multidisciplinary health teams in properly caring for young children in indigenous communities.
目的调查2岁以下土著儿童母乳喂养频率及其与早期断奶和贫血的相关因素。研究设计在巴西东北部阿拉戈斯州的13个土著社区进行了一项家庭横断面研究。方法对符合条件的儿童母亲进行访谈,收集社会经济、人口统计学、健康和喂养实践数据。采集血样评估血红蛋白浓度(Hb)。采用多重Cox、线性和泊松回归模型来检验与断奶和贫血相关的因素(Hb <;6个月及以上儿童110g /L)。结果在调查的1303个家庭中,145个家庭有2岁以下的孩子。6个月纯BF患病率仅为19%。观察到贫血(42.5%)、奶瓶喂养(70%)和安抚奶嘴使用(31%)的高频率。奶瓶和奶嘴的使用与早期断奶有关。奶瓶喂养与贫血显著相关(PR = 2.62;95%置信区间:1.42-4.84)。结论土著儿童的bf做法不符合世卫组织的建议。人工乳头的使用与早期断奶有关,奶瓶喂养与6个月后的贫血有关。这些发现强调了迫切需要采取干预措施,以促进、保护和支持土著人民的BF,指导多学科卫生团队妥善照顾土著社区的幼儿。
{"title":"Early weaning and anemia in children under 2 years old from indigenous peoples in Alagoas state, Brazil","authors":"Valéria Clarisse de Oliveira ,&nbsp;Paola Soledad Mosquera ,&nbsp;Tamara Rodrigues dos Santos ,&nbsp;Haroldo S. Ferreira ,&nbsp;Bárbara H. Lourenço ,&nbsp;Marly A. Cardoso","doi":"10.1016/j.hnm.2025.200318","DOIUrl":"10.1016/j.hnm.2025.200318","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the frequency of breastfeeding (BF) practices and factors associated with early weaning and anemia in indigenous children under 2 years of age.</div></div><div><h3>Study design</h3><div>A household cross-sectional study was conducted in 13 indigenous communities in Alagoas state, northeastern Brazil.</div></div><div><h3>Methods</h3><div>Mothers of eligible children were interviewed to gather socioeconomic, demographic, health, and feeding practice data. Blood samples were collected to assess the hemoglobin concentration (Hb). Multiple Cox, linear, and Poisson regression models were employed to examine the factors associated with weaning and anemia (Hb &lt; 110 g/L in children aged 6 months and older).</div></div><div><h3>Results</h3><div>Of the 1303 households surveyed, 145 had children under 2 years old. The prevalence of exclusive BF at 6 months was only 19 %. High frequencies of anemia (42.5 %), bottle-feeding (70 %), and pacifier use (31 %) were observed. The use of bottle and pacifier was associated with early weaning. Bottle-feeding was significantly associated with anemia (PR = 2.62; 95 % CI: 1.42–4.84) after adjusting for household wealth index.</div></div><div><h3>Conclusions</h3><div>BF practices among indigenous children do not meet WHO recommendations. The use of artificial nipples was linked to early weaning, and bottle feeding was associated with anemia after 6 months of age. These findings underscore the urgent need for interventions to promote, protect, and support BF in indigenous people, guiding multidisciplinary health teams in properly caring for young children in indigenous communities.</div></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"40 ","pages":"Article 200318"},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143873956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Human Nutrition and Metabolism
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