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Consumption of a variety of plant foods, ultra-processed foods, and risk for chronic disease: A dietary intervention 各种植物食品、超加工食品的摄入量与慢性病风险:膳食干预
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-03-01 DOI: 10.1016/j.hnm.2024.200258
Anaya Mitra , Kathy Thames , Anna Brown , Isabelle Shuster , Molly Rosenfield , Megan D. Baumler

Background

The reliance on ultra-processed foods (UPF) as a source of energy has increased over the last decade. Consumption of UPF is associated with increased calorie intake and increased risk for chronic disease. An intentional increase of a variety of non-ultra-processed plant foods may decrease UPF intake and reduce risk for chronic disease.

Methods

The objective of this study was to determine whether an intervention to increase in the number of varieties of non-ultra-processed plant foods consumed each week along with grocery reimbursement was associated with reduced intake of UPF and reduced risk of chronic disease. An 8-week dietary intervention with the intention for subjects (22 were recruited and started the study, while 19 subjects completed the study) to consume at least 30 varieties of non-ultra-processed plant foods per week was conducted. Subjects watched a weekly educational module, received recipes and grocery lists, and received reimbursement for non-ultra-processed plant foods that were purchased. Diet assessments were conducted by 24-h recall and 3-day diet records. Fasting plasma glucose, C-reactive protein, LDL and HDL cholesterol, and anthropomorphic measurements were assessed at four time points.

Results

The number of different types of non-ultra-processed plant foods consumed each week was significantly increased after the 8-week intervention compared to before (34.7 ± 10.8 vs 23.1 ± 12.1; p < 0.001). The number of ultra-processed foods consumed per day was significantly lower during the intervention compared to the control period (5.32 ± 1.65 vs 6.54 ± 2.04; p = 0.02). There were no significant changes to biochemical or anthropomorphic following the 8-week intervention.

Discussion

Educating individuals on the importance of the variety of plant foods intake along with reducing the financial barrier for purchasing plant foods may be an effective way to reduce reliance on ultra-processed foods. More research is needed to determine whether an increase in varieties of plant foods and reduction in ultra-processed food intake impacts risk for chronic disease.

背景过去十年来,人们越来越依赖超加工食品(UPF)作为能量来源。摄入超高加工食品与热量摄入增加和慢性病风险增加有关。本研究的目的是确定每周增加非超高加工植物性食品品种的干预措施是否与减少超高加工食品摄入量和降低慢性病风险有关。研究人员对受试者(22 名受试者被招募并开始研究,19 名受试者完成研究)进行了为期 8 周的饮食干预,目的是让他们每周至少摄入 30 种未经过度加工的植物性食品。受试者每周观看一个教育模块,获得食谱和杂货清单,并在购买非超高加工植物食品时获得报销。饮食评估通过 24 小时回忆和 3 天饮食记录进行。在四个时间点对空腹血浆葡萄糖、C 反应蛋白、低密度脂蛋白和高密度脂蛋白胆固醇以及人体形态测量进行评估。结果与干预前相比,干预 8 周后每周摄入不同类型的非超标加工植物食品的数量显著增加(34.7 ± 10.8 vs 23.1 ± 12.1; p <0.001)。与对照组相比,干预期间每天摄入的超加工食品数量明显减少(5.32 ± 1.65 vs 6.54 ± 2.04;p = 0.02)。讨论教育个人认识到摄入多种植物食品的重要性,同时减少购买植物食品的经济障碍,可能是减少对超加工食品依赖的有效方法。还需要进行更多的研究,以确定增加植物食品的种类和减少超加工食品的摄入量是否会影响慢性疾病的风险。
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引用次数: 0
Genetic variants and non-genetic factors associated with a high prevalence of vitamin D deficiency in full-term neonates in Malaysia 与马来西亚足月新生儿维生素 D 缺乏症高发有关的基因变异和非遗传因素
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-24 DOI: 10.1016/j.hnm.2024.200259
Siew-Siew Lee , King-Hwa Ling , Raman Subramaniam , Maiza Tusimin , Kartini Farah Rahim , Su-Peng Loh

A high prevalence of vitamin D deficiency has been reported in Malaysian pregnant women, indicating that neonates at birth are at increased risk of vitamin D deficiency. Factors including low dietary vitamin D intake and single nucleotide polymorphisms in the vitamin D metabolism genes have been associated with this deficiency in the population. However, there was limited data available regarding the prevalence of neonatal vitamin D deficiency and the factors associated with it among neonates in Malaysia. Therefore, this study aimed to determine the prevalence of vitamin D deficiency and explore the associations between maternal and neonatal gene polymorphisms, as well as non-genetic factors and neonatal vitamin D deficiency. A total of 217 mother-neonate dyads were recruited for this study. Data on skin type, maternal sun exposure, dietary intake, as well as maternal and neonatal 25-hydroxyvitamin D (25OHD) concentrations were collected. Maternal and neonatal vitamin D Receptor (VDR) SNP (rs2228570) and Group-specific component (GC) SNPs (rs4588 and rs7041) genotypes were determined using high-resolution melting (HRM) and restriction fragment length polymorphism, respectively. The results showed that 60.4%, 71.4% and 95.4% of neonates had cord blood 25OHD levels below 25 nmol/L, 30 nmol/L and 50 nmol/L, respectively. After adjusting for the maternal vitamin D status, the maternal VDR rs2228570 GG genotype was significantly associated with neonatal vitamin D deficiency (25OHD<30 nmol/L) (aOR = 2.63, 95% CI: 1.18–5.87, p = 0.018). Maternal vitamin D supplement intake was found to be a protective factor. However, maternal and neonatal vitamin D binding protein (VDBP) SNPs were not associated with neonatal vitamin D deficiency. The high prevalence of neonatal vitamin D deficiency reported in this study indicates the urgent need for the development and implementation of strategies to improve neonatal vitamin D status. The findings suggest that maternal supplementation may be an effective approach to enhance the vitamin D status of neonates.

据报道,马来西亚孕妇维生素D缺乏症的发病率很高,这表明新生儿出生时维生素D缺乏症的风险增加。膳食中维生素 D 摄入量低和维生素 D 代谢基因中的单核苷酸多态性等因素与人群中的维生素 D 缺乏症有关。然而,有关马来西亚新生儿维生素 D 缺乏症的发病率及其相关因素的数据却很有限。因此,本研究旨在确定维生素 D 缺乏症的患病率,并探讨母体和新生儿基因多态性以及非遗传因素与新生儿维生素 D 缺乏症之间的关联。本研究共招募了 217 对母婴组合。研究人员收集了有关肤质、母体日晒、饮食摄入以及母体和新生儿 25- 羟基维生素 D(25OHD)浓度的数据。母体和新生儿的维生素 D 受体(VDR)SNP(rs2228570)和群体特异性成分(GC)SNP(rs4588 和 rs7041)基因型分别通过高分辨率熔解(HRM)和限制性片段长度多态性进行了测定。结果显示,分别有60.4%、71.4%和95.4%的新生儿脐血25OHD水平低于25 nmol/L、30 nmol/L和50 nmol/L。调整母体维生素 D 状态后,母体 VDR rs2228570 GG 基因型与新生儿维生素 D 缺乏(25OHD<30 nmol/L)显著相关(aOR = 2.63,95% CI:1.18-5.87,p = 0.018)。研究发现,母体维生素 D 补充剂的摄入是一个保护因素。然而,母体和新生儿维生素 D 结合蛋白 (VDBP) SNPs 与新生儿维生素 D 缺乏无关。本研究中报告的新生儿维生素 D 缺乏症的高发病率表明,迫切需要制定和实施改善新生儿维生素 D 状态的策略。研究结果表明,母体补充维生素D可能是改善新生儿维生素D状况的有效方法。
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引用次数: 0
The role of nutrition on the treatment of Covid 19 营养对治疗 Covid 的作用 19
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-24 DOI: 10.1016/j.hnm.2024.200255
Samer Younes

The rapid and extensive transmission of the SARS-CoV-2 virus has led to a worldwide COVID-19 pandemic. Initially thought to be an acute illness, many patients have reported persistent and recurring symptoms even after the infectious period. This has given rise to a new epidemic known as "long-COVID" or post-acute sequelae of coronavirus disease, which has significantly impacted the lives of millions of individuals globally. The symptoms of both COVID-19 vary from person to person, but they share similarities with other respiratory viruses, such as chest pain, shortness of breath, and fatigue, as well as adverse effects on metabolic and pulmonary health. Nutrition plays a crucial role in immune function and metabolic health, and therefore, it is believed to have an impact on reducing the risk or severity of symptoms for both COVID-19. However, despite the importance of nutrition in these physiological functions related to COVID-19, the exact role of nutrition in the onset or severity of COVID-19 infection is still not fully understood. This review aims to explore established and emerging nutrition approaches that may have a role in COVID-19, while emphasizing the significance of established nutrition and clinical practice guidelines as the primary resources for patients and healthcare practitioners.

SARS-CoV-2 病毒迅速而广泛的传播导致了 COVID-19 在全球范围内的大流行。最初人们认为这是一种急性疾病,但许多患者报告说,即使在感染期过后,症状仍持续存在并反复出现。这引发了一种被称为 "长COVID "或冠状病毒病急性后遗症的新流行病,严重影响了全球数百万人的生活。COVID-19 的症状因人而异,但与其他呼吸道病毒有相似之处,如胸痛、气短和疲劳,以及对新陈代谢和肺部健康的不利影响。营养对免疫功能和新陈代谢健康起着至关重要的作用,因此,营养被认为对降低 COVID-19 的风险或症状严重程度有影响。然而,尽管营养在这些与 COVID-19 相关的生理功能中具有重要作用,但营养在 COVID-19 感染的发病或严重程度中的确切作用仍未得到充分了解。本综述旨在探讨可能对 COVID-19 起作用的既有和新兴营养方法,同时强调既有营养和临床实践指南作为患者和医疗从业人员主要资源的重要性。
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引用次数: 0
Association between overweight/obesity perception, actual body weight and cardiometabolic risk among healthy Ghanaian adults 加纳健康成年人对超重/肥胖的认知、实际体重与心脏代谢风险之间的关系
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-18 DOI: 10.1016/j.hnm.2024.200253
Abdul-Malik Bawah , Annan Reginald A , Haadi Abdul-Rahman

Background

The global rise in obesity, particularly among black Africans in developing nations experiencing nutritional transitions, underscores the importance of exploring Overweight/Obesity Perception (OP) as a crucial factor in maintaining an optimal body weight. Incorrect body image perception may impede efforts to achieve the desired body weight, leading to adverse outcomes related to Cardiometabolic Diseases (CMD). This cross-sectional study investigated the interplay between overweight/obesity perception, actual body weight, and CMD risk in a cohort of healthy Ghanaian adults.

Methods

A total of 302 apparently healthy adults, aged 25–60 years, with Dagomba ancestry, were recruited from three communities. Participants were screened based on age, ancestry, history of communicable and Non-Communicable Diseases (NCD), and use of antidiabetic, lipid-lowering, and antihypertensive drugs. Anthropometric assessments and blood sample collections for biochemical analysis were conducted. Body image perception was measured using the Stunkard Figure Rating Scale (SFRS). Data were analyzed using descriptive statistics, chi-square tests, correlation analysis, logistic regression, and multivariate analysis.

Results

Participants had a mean age of 38.28 ± 10.88, with 61.6% being women. While 47% accurately perceived their body weight, 53% had incorrect perceptions. Notably, 47.2% underestimated and 8.5% overestimated their weight status. Among overweight individuals, 33% underestimated and 9.4% overestimated their weight, whereas among the obese, 66.7% and 33.3% respectively had inaccurate perceptions. Gender, serum triglyceride levels, and waist circumference were significantly associated with weight perception. About 55% of overweight/obese participants and 62.1% with high waist circumference did not express a desire to lose weight. Multiple logistic regression revealed that both overweight (AOR = 6, 95% CI (1.8–20.2), p < 0.05) and obesity (AOR = 20.5, 95% CI (5–84.9), p < 0.05) significantly increased the odds of CMD.

Conclusion

The findings underscore the association between overweight/obesity and an elevated risk of CMD. This emphasizes the imperative for public health interventions aimed at promoting an ideal body weight and highlighting the impact of overweight/obesity on CMD risk factors.

背景肥胖症在全球范围内呈上升趋势,尤其是在经历营养转型的发展中国家的非洲黑人中,这凸显了探讨超重/肥胖感知(OP)作为保持最佳体重的关键因素的重要性。不正确的身体形象认知可能会阻碍实现理想体重的努力,从而导致与心脏代谢疾病(CMD)相关的不良后果。这项横断面研究调查了加纳健康成年人队列中超重/肥胖认知、实际体重和 CMD 风险之间的相互作用。根据年龄、血统、传染病和非传染性疾病(NCD)病史以及抗糖尿病、降血脂和降血压药物的使用情况对参与者进行筛选。此外,还进行了人体测量评估和血液样本采集以进行生化分析。身体形象感知采用斯通卡德体型评定量表(SFRS)进行测量。采用描述性统计、卡方检验、相关分析、逻辑回归和多变量分析对数据进行了分析。47%的人对自己的体重感知准确,53%的人感知错误。值得注意的是,47.2%的人低估了自己的体重状况,8.5%的人高估了自己的体重状况。在超重者中,33%的人低估了自己的体重,9.4%的人高估了自己的体重,而在肥胖者中,分别有66.7%和33.3%的人对自己的体重认知不准确。性别、血清甘油三酯水平和腰围与体重感知显著相关。约 55% 的超重/肥胖参与者和 62.1% 的高腰围者没有表达过减肥的愿望。多重逻辑回归显示,超重(AOR = 6,95% CI (1.8-20.2),p < 0.05)和肥胖(AOR = 20.5,95% CI (5-84.9),p < 0.05)都会明显增加患慢性阻塞性肺病的几率。研究结果强调了超重/肥胖与慢性阻塞性肺病风险升高之间的关系,这就强调了必须采取公共卫生干预措施,以促进理想体重,并强调超重/肥胖对慢性阻塞性肺病风险因素的影响。
{"title":"Association between overweight/obesity perception, actual body weight and cardiometabolic risk among healthy Ghanaian adults","authors":"Abdul-Malik Bawah ,&nbsp;Annan Reginald A ,&nbsp;Haadi Abdul-Rahman","doi":"10.1016/j.hnm.2024.200253","DOIUrl":"https://doi.org/10.1016/j.hnm.2024.200253","url":null,"abstract":"<div><h3>Background</h3><p>The global rise in obesity, particularly among black Africans in developing nations experiencing nutritional transitions, underscores the importance of exploring Overweight/Obesity Perception (OP) as a crucial factor in maintaining an optimal body weight. Incorrect body image perception may impede efforts to achieve the desired body weight, leading to adverse outcomes related to Cardiometabolic Diseases (CMD). This cross-sectional study investigated the interplay between overweight/obesity perception, actual body weight, and CMD risk in a cohort of healthy Ghanaian adults.</p></div><div><h3>Methods</h3><p>A total of 302 apparently healthy adults, aged 25–60 years, with Dagomba ancestry, were recruited from three communities. Participants were screened based on age, ancestry, history of communicable and Non-Communicable Diseases (NCD), and use of antidiabetic, lipid-lowering, and antihypertensive drugs. Anthropometric assessments and blood sample collections for biochemical analysis were conducted. Body image perception was measured using the Stunkard Figure Rating Scale (SFRS). Data were analyzed using descriptive statistics, chi-square tests, correlation analysis, logistic regression, and multivariate analysis.</p></div><div><h3>Results</h3><p>Participants had a mean age of 38.28 ± 10.88, with 61.6% being women. While 47% accurately perceived their body weight, 53% had incorrect perceptions. Notably, 47.2% underestimated and 8.5% overestimated their weight status. Among overweight individuals, 33% underestimated and 9.4% overestimated their weight, whereas among the obese, 66.7% and 33.3% respectively had inaccurate perceptions. Gender, serum triglyceride levels, and waist circumference were significantly associated with weight perception. About 55% of overweight/obese participants and 62.1% with high waist circumference did not express a desire to lose weight. Multiple logistic regression revealed that both overweight (AOR = 6, 95% CI (1.8–20.2), p &lt; 0.05) and obesity (AOR = 20.5, 95% CI (5–84.9), p &lt; 0.05) significantly increased the odds of CMD.</p></div><div><h3>Conclusion</h3><p>The findings underscore the association between overweight/obesity and an elevated risk of CMD. This emphasizes the imperative for public health interventions aimed at promoting an ideal body weight and highlighting the impact of overweight/obesity on CMD risk factors.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200253"},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266614972400015X/pdfft?md5=54e38d679a11bf894f3d4270b0d6e706&pid=1-s2.0-S266614972400015X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139936178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The higher dietary inflammation is associated with a higher burden of multimorbidity of cardio-metabolic and mental health disorders in an urbanizing community of southern India: A cross-sectional analysis for the APCAPS cohort 在印度南部的一个城市化社区中,较高的饮食炎症与较高的心血管代谢疾病和精神疾病的多病负担有关:对 APCAPS 队列的横断面分析
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-15 DOI: 10.1016/j.hnm.2024.200254
Hemant Mahajan , Judith Lieber , Poppy Alice Carson Mallinson , Santhi Bhogadi , Santosh Kumar Banjara , Sanjay Kinra , Bharati Kulkarni

Background & aims

Habitual dietary pattern has been shown to be a major modulator of systemic inflammation and is considered a modifiable risk factor for cardio-metabolic diseases (CMDs) and mental health disorders. We examined whether dietary-inflammation is associated with the multimorbidity of CMDs and mental health disorders in urbanizing-villages in southern India. We hypothesized that the participants with higher dietary-inflammation would have a higher burden of multimorbidity.

Materials & methods

We conducted a cross-sectional analysis of 5984 adults (53% male) participating in the Andhra Pradesh Children and Parents' Study. We assessed dietary-inflammation using dietary inflammatory index (DII®) based on intake of 27 micro- and macro-nutrients which were measured using a validated food-frequency-questionnaires. The CMDs and mental health disorders were assessed using standardized clinical procedures and validated questionnaires. ‘Multimorbidity’ was defined as a co-existence of one or more CMDs (hypertension, diabetes, myocardial infarction, heart failure, angina and stroke) and one or more mental health disorders (depression and anxiety). The association of multimorbidity with dietary-inflammation was examined using robust Poisson regression.

Results

The prevalence of multimorbidity was 3.5% and ∼75% of participants were consuming a pro-inflammatory diet (DII >0.0). As compared to the 1st DII-quartile (least dietary-inflammatory group), the adjusted prevalence ratio (95% confidence interval) for the presence of multimorbidity was 1.46(0.87, 2.46) for 2nd, 1.75(1.05, 2.89) for 3rd, and 1.77(1.06, 2.96) for 4th DII-quartile (p-trend = 0.021). There was no evidence of an interaction between DII and sex on multimorbidity.

Conclusions

Dietary-inflammation had a positive linear association with the multimorbidity, which suggest that even modest reduction in dietary-inflammation may reduce the multimorbidity burden.

背景与ampamp; 目的习惯性饮食模式已被证明是全身炎症的主要调节因素,并被认为是心血管代谢疾病(CMDs)和精神疾病的可调节风险因素。我们研究了在印度南部的城市化村庄中,饮食炎症是否与心血管代谢疾病和精神疾病的多病症相关。我们假设,膳食炎症程度较高的参与者的多病负担会更重。材料& 方法我们对参与安得拉邦儿童和家长研究的 5984 名成人(53% 为男性)进行了横断面分析。我们使用膳食炎症指数(DII®)评估了膳食炎症,该指数基于 27 种微量和宏量营养素的摄入量,并通过有效的食物频率问卷进行了测量。采用标准化临床程序和有效问卷对慢性疾病和精神疾病进行评估。多病 "是指同时患有一种或多种慢性疾病(高血压、糖尿病、心肌梗塞、心力衰竭、心绞痛和中风)和一种或多种精神疾病(抑郁症和焦虑症)。采用稳健泊松回归法研究了多病症与饮食炎症的关系。结果多病症患病率为 3.5%,75% 的参与者摄入了促炎症饮食(DII >0.0)。与第1个DII四分位数组(饮食最不发炎组)相比,第2个DII四分位数组、第3个DII四分位数组和第4个DII四分位数组的多病发生率调整比(95%置信区间)分别为1.46(0.87,2.46)、1.75(1.05,2.89)和1.77(1.06,2.96)(p-趋势=0.021)。结论膳食炎症与多病症呈正线性关系,这表明即使适度减少膳食炎症也可减轻多病症负担。
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引用次数: 0
Increased dependency on dietary supplements for calcium, vitamin B1 and vitamin C intake during the COVID-19 pandemic among healthy adults: Data from the eighth Korea national health and nutrition examination survey (2019–2020) 在 COVID-19 大流行期间,健康成年人钙、维生素 B1 和维生素 C 摄入量对膳食补充剂的依赖性增加:第八次韩国国民健康与营养状况调查(2019-2020 年)数据
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-15 DOI: 10.1016/j.hnm.2024.200252
Jung Min Cho

Objective

This study aimed to assess the data of a healthy population at the Korean national level to explore the prevalence of dietary supplement (DS) use changes and the contribution of DSs to micronutrient intake during the pandemic.

Research methods and procedures

Data from the first (2019, before the COVID-19 pandemic) and second (2020, the year that the acute pandemic caused substantial life changes) years of the eighth Korea National Health and Nutrition Examination Survey (KNHANES) were investigated using a weighted complex sample design. Conversions (supplementation/dietary intake (S/D ratio), supplementation to total intake (StT), and supplementation to reference (StR)) were presented to investigate DS dependency and demonstrate that individuals’ nutrient intake derived from DSs increased.

Results

The total adult population was 4871 and 4421 in 2019 and 2020, respectively. Among healthy adults, 64.2% took DSs in 2020, 7.2% higher than that in 2019 (P < 0.001). Among those aged 30–49 years, 70.2% used DSs in 2020, a 9.1% increase from 2019 (P = 0.015). The S/D ratio of vitamin C intake was 6.45 ± 0.95 in 2020, which was greater than that in 2019 (3.82 ± 0.47, P = 0.038). The StT of Ca intake was 7.79 ± 0.98% in 2020, which was greater than that in 2019 (4.89 ± 0.60%, P = 0.020). The StR of vitamin B1 intake was greater in 2020 (505.01 ± 36.95%) than in 2019 (368.82 ± 29.55%, P = 0.004).

Conclusion

DS dependency greatly increased during the COVID-19 pandemic and was accompanied by increased DS consumption and decreased Ca, vitamin B1, and vitamin C intake in the healthy Korean population.

研究方法和程序采用加权复合样本设计,调查了第八次韩国国民健康与营养调查(KNHANES)第一年(2019 年,COVID-19 大流行之前)和第二年(2020 年,急性大流行导致生活发生重大变化的一年)的数据。结果2019年和2020年的成年总人口分别为4871人和4421人。在健康成年人中,2020 年有 64.2% 的人服用 DSs,比 2019 年高出 7.2% (P < 0.001)。在 30-49 岁的人群中,2020 年有 70.2% 的人使用 DSs,比 2019 年增加了 9.1%(P = 0.015)。2020 年维生素 C 摄入量的 S/D 比率为 6.45 ± 0.95,高于 2019 年(3.82 ± 0.47,P = 0.038)。2020 年 Ca 摄入量的 StT 为 7.79 ± 0.98%,高于 2019 年(4.89 ± 0.60%,P = 0.020)。ConclusionDS dependency greatly increased during the COVID-19 pandemic and was accompanied with increased DS consumption and decreased Ca, vitamin B1, and vitamin C intake in the healthy Korean population.
{"title":"Increased dependency on dietary supplements for calcium, vitamin B1 and vitamin C intake during the COVID-19 pandemic among healthy adults: Data from the eighth Korea national health and nutrition examination survey (2019–2020)","authors":"Jung Min Cho","doi":"10.1016/j.hnm.2024.200252","DOIUrl":"10.1016/j.hnm.2024.200252","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to assess the data of a healthy population at the Korean national level to explore the prevalence of dietary supplement (DS) use changes and the contribution of DSs to micronutrient intake during the pandemic.</p></div><div><h3>Research methods and procedures</h3><p>Data from the first (2019, before the COVID-19 pandemic) and second (2020, the year that the acute pandemic caused substantial life changes) years of the eighth Korea National Health and Nutrition Examination Survey (KNHANES) were investigated using a weighted complex sample design. Conversions (supplementation/dietary intake (S/D ratio), supplementation to total intake (StT), and supplementation to reference (StR)) were presented to investigate DS dependency and demonstrate that individuals’ nutrient intake derived from DSs increased.</p></div><div><h3>Results</h3><p>The total adult population was 4871 and 4421 in 2019 and 2020, respectively. Among healthy adults, 64.2% took DSs in 2020, 7.2% higher than that in 2019 (P &lt; 0.001). Among those aged 30–49 years, 70.2% used DSs in 2020, a 9.1% increase from 2019 (P = 0.015). The S/D ratio of vitamin C intake was 6.45 ± 0.95 in 2020, which was greater than that in 2019 (3.82 ± 0.47, P = 0.038). The StT of Ca intake was 7.79 ± 0.98% in 2020, which was greater than that in 2019 (4.89 ± 0.60%, P = 0.020). The StR of vitamin B<sub>1</sub> intake was greater in 2020 (505.01 ± 36.95%) than in 2019 (368.82 ± 29.55%, P = 0.004).</p></div><div><h3>Conclusion</h3><p>DS dependency greatly increased during the COVID-19 pandemic and was accompanied by increased DS consumption and decreased Ca, vitamin B<sub>1</sub>, and vitamin C intake in the healthy Korean population.</p></div>","PeriodicalId":36125,"journal":{"name":"Human Nutrition and Metabolism","volume":"36 ","pages":"Article 200252"},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666149724000148/pdfft?md5=c8888b8ee4c35971b4307b4fb775e9e8&pid=1-s2.0-S2666149724000148-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139823587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Iron/foliate utilization and associated factors among pregnant women attending antenatal care at public hospitals in Bench Sheko Zone, South West, Ethiopia 埃塞俄比亚西南部 Bench Sheko 区公立医院产前检查孕妇的铁/叶酸利用率及相关因素
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-10 DOI: 10.1016/j.hnm.2024.200245
Zewditu Alelign, Olantu Mekonnen, Emebet Adugnaw

Background

Iron/foliate affects the lives of more than two billion people, accounting for over 30% of global population which is the highest in developing countries and about 18% of maternal mortality in low- and middle-income countries. Iron/foliate supplementation for pregnant mothers is the most cost-effective method of reducing iron deficiency, low birth weight, and neural tube defects among pregnant mothers and newborns in resource-limited countries like Ethiopia, so the purpose of this study has been to assess the iron/foliate utilization status of pregnant mothers and associated factors among pregnant mothers.

Method

The study have used institution-based cross-sectional design with systematic random sampling, binary and multiple logistic regression to identify significantly associated variables, and a single population proportion formula to determine the sample size.

Result

From the total of 318 participants only 32.1% of them utilized iron/foliate adequately. Marital status (AOR; 0.03 95%, CL (0.01–0.86), occupation (AOR; 11.12 95%, CL (1.95–69.05), gestation age when ANC visit started (AOR; 0.23 95%, CL (0.07–0.83), health education(AOR; 36.51 95%, CL (10.14–131.46), waiting time(AOR; 0.07 95%, CL (0.02–0.27) and knowledge (AOR; 0.17 95%, CL (0.05–0.57) were significantly associated variables with the outcome variable.

Conclusion

According to this study, 32.1 % utilized iron/foliate adequately, whereas the remaining 67.9 % did not yet. Moreover, this study identified major associated variables with iron/foliate utilization status, including marital status, occupation, gestation age when ANC visit started, health education, average wait time, and knowledge of mothers on anemia/iron.

背景铁/叶酸影响着 20 多亿人的生活,占全球人口的 30%以上,其中发展中国家的比例最高,约占中低收入国家孕产妇死亡率的 18%。在埃塞俄比亚等资源有限的国家,为孕产妇补充铁/叶是减少孕产妇和新生儿缺铁、出生体重不足和神经管缺陷的最具成本效益的方法。方法本研究采用基于机构的横断面设计和系统随机抽样、二元和多元逻辑回归来确定显著相关的变量,并采用单一人口比例公式来确定样本量。 结果在总共 318 名参与者中,只有 32.1%的人充分使用了铁/叶酸。婚姻状况(AOR;0.03 95%,CL(0.01-0.86))、职业(AOR;11.12 95%,CL(1.95-69.05))、开始产前检查时的孕龄(AOR;0.23 95%,CL(0.07-0.83))、健康教育程度(AOR;36.51 95%,CL(10.14-131.46))、等待时间(AOR;0.结论根据本研究,32.1%的人充分使用了铁/叶酸,而其余 67.9%的人尚未使用。此外,本研究还发现了与铁剂/叶酸利用状况相关的主要变量,包括婚姻状况、职业、开始产前检查时的孕龄、健康教育、平均等待时间以及母亲对贫血/铁剂的了解程度。
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引用次数: 0
Ketogenic diet in clinical practices 生酮饮食在临床实践中的应用
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-02-02 DOI: 10.1016/j.hnm.2024.200250
İbrahim Hakkı Çağıran , Dursun Alper Yılmaz

Epilepsy is a medical condition characterized by seizures. While antiepileptic drugs can effectively control seizures in most epilepsy patients, there exists a subtype known as resistant epilepsy in which drugs prove ineffective in managing seizure activity. Furthermore, some patients experience undesirable side effects from these medications, leading to the discontinuation of antiepileptic drug use. In such situations and others like them, the ketogenic diet is recommended as an alternative treatment approach, one that does not rely on pharmacological interventions The fundamental rationale supporting the potential efficacy of the ketogenic diet in epilepsy treatment lies in the fact that, in certain circumstances such as fasting, ketone bodies are utilized as the primary energy source for neurons, as opposed to glucose. To facilitate the generation of ketone bodies while ensuring ease and flexibility of implementation, various types of ketogenic diets have been developed. The choice of ketogenic diet approach in the treatment of epilepsy can be tailored based on the individual tolerability of patients. This meta-analysis aims to consolidate the evidence regarding the impact of ketogenic diets on patients with epilepsy in clinical practice.

癫痫是一种以癫痫发作为特征的疾病。虽然抗癫痫药物能有效控制大多数癫痫患者的癫痫发作,但也存在一种被称为抗药性癫痫的亚型,在这种情况下,药物无法有效控制癫痫发作活动。此外,一些患者会因这些药物产生不良副作用而停止使用抗癫痫药物。支持生酮饮食在癫痫治疗中的潜在疗效的基本原理在于,在禁食等特定情况下,酮体被用作神经元的主要能量来源,而不是葡萄糖。为了促进酮体的产生,同时确保实施的简便性和灵活性,人们开发了各种类型的生酮饮食。在治疗癫痫时,可根据患者的个体耐受性选择生酮饮食方法。本荟萃分析旨在整合临床实践中有关生酮饮食对癫痫患者影响的证据。
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引用次数: 0
The effects of omega-3 fatty acid supplementation on serum myostatin, body composition, blood glucose, lipid profile and hs-CRP level in overweight men with coronary heart disease: A randomized double-blind placebo controlled clinical trial 补充欧米伽-3 脂肪酸对患有冠心病的超重男性血清肌生成素、身体成分、血糖、血脂和 hs-CRP 水平的影响:随机双盲安慰剂对照临床试验
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-28 DOI: 10.1016/j.hnm.2024.200248
Mohammad sharifzadeh , Leila setayesh , Mohammad Reza Emami , Shirin Jafari Salim , Mo hammad Hassan Javanbakht

Background

Cardiovascular diseases, including heart cachexia, are considered as one of the most critical issues in health care that could be affected by several factors, such as myostatin whose critical role has been confirmed in the progress of heart cachexia and cardiac muscle dysfunction. This study was conducted to clarify the precise role of omega-3 polyunsaturated fatty acid (ω-3PUFA) on lipid profile, blood glucose, body composition, and serum level of myostatin in individuals with coronary artery disease (CAD).

Materials and methods

Forty-two adult males (aged 45–65 years) with CAD had been confirmed by angiography were randomly divided into two groups, group 1 received omega-3 (1200mg daily) and group 2 received placebo (paraffin) for 8 weeks. The serum level of myostatin was measured using an ELISA kit in the beginning and at the end of the intervention. Moreover, body composition and anthropometric measurements of the patients were also evaluated.

Result

A significant difference was observed in the myostatin level after 8weeks of intervention with omega3 supplement between omega3 and placebo group (p = 0.02).There was a significant difference in high-sensitivity C-reactive protein(hsCRP) concentration (p = 0.02) and low-density lipoprotein cholesterol (p = 0.01) between intervention group and control group at the end of the intervention. However, no statistically significant changes were seen in the body composition, anthropometric parameters, fasting insulin level, and fasting blood sugar within and between the groups.

Conclusion

Omega-3 oral supplementation may improve the status of CAD patients by decreasing the level of myostatin, LDL-C and hs-CRP.

背景心血管疾病,包括心脏恶病质,被认为是医疗保健领域最关键的问题之一,它可能受到多种因素的影响,例如肌他汀,其在心脏恶病质和心肌功能障碍的进展中的关键作用已被证实。本研究旨在阐明欧米伽-3 多不饱和脂肪酸(ω-3PUFA)对冠状动脉疾病(CAD)患者的血脂、血糖、身体成分和血清肌生成素水平的确切作用。材料和方法将 42 名经血管造影证实患有 CAD 的成年男性(45-65 岁)随机分为两组,第一组接受欧米伽-3(每天 1200 毫克)治疗,第二组接受安慰剂(石蜡)治疗,为期 8 周。在干预开始和结束时,使用酶联免疫吸附试剂盒测定血清中肌生长激素的水平。干预结束时,干预组和对照组的高敏C反应蛋白(hsCRP)浓度(p = 0.02)和低密度脂蛋白胆固醇(p = 0.01)有显著差异。结论口服欧米伽-3补充剂可降低肌生成素、低密度脂蛋白胆固醇和hs-CRP的水平,从而改善CAD患者的状况。
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引用次数: 0
Enrichment with citrus peels as a strategy for improving the health benefits and nutritional value of breakfast cereals: A review 富含柑橘皮作为改善谷物早餐健康益处和营养价值的一种策略:综述
Q3 ENDOCRINOLOGY & METABOLISM Pub Date : 2024-01-24 DOI: 10.1016/j.hnm.2024.200239
Ayokunle Olubode Ademosun

Breakfast cereals (BFCs) are a popular choice for breakfast and the BFC market is growing at an annual rate of 4.1 % and stands as a 70 billion dollar enterprise today. However, there are a number of questions raised about the medicinal properties of BFCs as they are processed foods lot of added refined sugars and reduced fibres especially when made from processed grains. Therefore, improving the medicinal values of BFCs will include minimizing the refined sugar content, increasing the fibre content and fortifying with natural bioactive compounds which possess medicinal properties. Citrus peels are rich in fibre and bioactive compounds, even though they are considered a waste in many countries. Incorporating citrus peels into BFCs without adversely affecting the sensory properties will enhance the medicinal properties of BFCs as the peels have a number of already established medicinal properties. Citrus peel-enriched BFCs could be a tool in Functional Nutrition as they will not only supply needed nutrients to start the day, but they will also be able to prevent and manage degenerative conditions through their ability to modulate other factors connected with diseases such as inflammation regulation, mood disorders and weight control.

早餐谷物食品(BFCs)是人们早餐的首选,早餐谷物食品市场正以每年 4.1% 的速度增长,如今已成为价值 700 亿美元的企业。然而,人们对早餐谷物食品的药用价值提出了许多质疑,因为它们是添加了大量精制糖和减少了纤维的加工食品,尤其是由加工谷物制成的早餐谷物食品。因此,要提高碱性食品的药用价值,就要尽量减少精制糖的含量,增加纤维含量,并添加具有药用价值的天然生物活性化合物。柑橘皮富含纤维和生物活性化合物,尽管在许多国家它们被视为废物。在不影响感官特性的情况下,将柑橘皮添加到 BFC 中会增强 BFC 的药用特性,因为柑橘皮具有许多已被证实的药用特性。富含柑橘皮的 BFC 可以成为功能性营养的一种工具,因为它们不仅能提供一天开始所需的营养,还能通过调节与疾病相关的其他因素(如炎症调节、情绪障碍和体重控制)来预防和控制退化性疾病。
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引用次数: 0
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Human Nutrition and Metabolism
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