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A Wearable Tele-Health System towards Monitoring COVID-19 and Chronic Diseases 用于监测新冠肺炎和慢性病的可穿戴远程健康系统
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-30 DOI: 10.1109/RBME.2021.3069815
Wei Jiang;Sumit Majumder;Samarth Kumar;Sophini Subramaniam;Xiaohe Li;Ridha Khedri;Tapas Mondal;Mansour Abolghasemian;Imran Satia;M. Jamal Deen
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic since early 2020. The coronavirus disease 2019 (COVID-19) has already caused more than three million deaths worldwide and affected people's physical and mental health. COVID-19 patients with mild symptoms are generally required to self-isolate and monitor for symptoms at least for 14 days in the case the disease turns towards severe complications. In this work, we overviewed the impact of COVID-19 on the patients' general health with a focus on their cardiovascular, respiratory and mental health, and investigated several existing patient monitoring systems. We addressed the limitations of these systems and proposed a wearable telehealth solution for monitoring a set of physiological parameters that are critical for COVID-19 patients such as body temperature, heart rate, heart rate variability, blood oxygen saturation, respiratory rate, blood pressure, and cough. This physiological information can be further combined to potentially estimate the lung function using artificial intelligence (AI) and sensor fusion techniques. The prototype, which includes the hardware and a smartphone app, showed promising results with performance comparable to or better than similar commercial devices, thus potentially making the proposed system an ideal wearable solution for long-term monitoring of COVID-19 patients and other chronic diseases.
严重急性呼吸系统综合征冠状病毒2型自2020年初以来引发了一场大流行。2019冠状病毒病(新冠肺炎)已在全球造成300多万人死亡,并影响人们的身心健康。症状轻微的新冠肺炎患者通常需要自我安慰,并在病情发展为严重并发症的情况下监测症状至少14天。在这项工作中,我们概述了新冠肺炎对患者总体健康的影响,重点关注患者的心血管、呼吸和心理健康,并调查了几种现有的患者监测系统。我们解决了这些系统的局限性,并提出了一种可穿戴远程健康解决方案,用于监测一组对新冠肺炎患者至关重要的生理参数,如体温、心率、心率变异性、血氧饱和度、呼吸频率、血压和咳嗽。可以使用人工智能(AI)和传感器融合技术进一步组合这些生理信息,以潜在地估计肺功能。该原型包括硬件和智能手机应用程序,显示出了与类似商业设备相当或更好的性能,有望成为长期监测新冠肺炎患者和其他慢性病的理想可穿戴解决方案。
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引用次数: 34
A Survey on Mathematical, Machine Learning and Deep Learning Models for COVID-19 Transmission and Diagnosis 新冠肺炎传播与诊断的数学、机器学习和深度学习模型综述
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-26 DOI: 10.1109/RBME.2021.3069213
J. Christopher Clement;VijayaKumar Ponnusamy;K.C. Sriharipriya;R. Nandakumar
COVID-19 is a life threatening disease which has a enormous global impact. As the cause of the disease is a novel coronavirus whose gene information is unknown, drugs and vaccines are yet to be found. For the present situation, disease spread analysis and prediction with the help of mathematical and data driven model will be of great help to initiate prevention and control action, namely lockdown and qurantine. There are various mathematical and machine-learning models proposed for analyzing the spread and prediction. Each model has its own limitations and advantages for a particluar scenario. This article reviews the state-of-the art mathematical models for COVID-19, including compartment models, statistical models and machine learning models to provide more insight, so that an appropriate model can be well adopted for the disease spread analysis. Furthermore, accurate diagnose of COVID-19 is another essential process to identify the infected person and control further spreading. As the spreading is fast, there is a need for quick auotomated diagnosis mechanism to handle large population. Deep-learning and machine-learning based diagnostic mechanism will be more appropriate for this purpose. In this aspect, a comprehensive review on the deep learning models for the diagnosis of the disease is also provided in this article.
新冠肺炎是一种威胁生命的疾病,具有巨大的全球影响。由于该疾病的病因是一种基因信息未知的新型冠状病毒,药物和疫苗尚未找到。就目前的情况而言,借助数学和数据驱动的模型对疾病传播进行分析和预测,将有助于启动预防和控制行动,即封锁和qurantine。有各种数学和机器学习模型被提出用于分析传播和预测。对于特定的场景,每个模型都有自己的局限性和优势。本文回顾了新冠肺炎最先进的数学模型,包括区间模型、统计模型和机器学习模型,以提供更多的见解,从而可以很好地采用适当的模型进行疾病传播分析。此外,准确诊断新冠肺炎是识别感染者和控制进一步传播的另一个重要过程。由于传播速度快,因此需要快速的辅助诊断机制来处理大量人群。基于深度学习和机器学习的诊断机制将更适合于此目的。在这方面,本文还对用于诊断该疾病的深度学习模型进行了全面的综述。
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引用次数: 47
Recent Advances in Atherosclerotic Disease Screening Using Pervasive Healthcare 普及医疗筛查动脉粥样硬化疾病的最新进展
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-18 DOI: 10.1109/RBME.2021.3081180
Jingjing Luo;Zhengrong Yan;Shijie Guo;Wei Chen
Atherosclerosis screening helps the medical model transform from therapeutic medicine to preventive medicine by assessing degree of atherosclerosis prior to the occurrence of fatal vascular events. Pervasive screening emphasizes atherosclerotic monitoring with easy access, quick process, and advanced computing. In this work, we introduced five cutting-edge pervasive technologies including imaging photoplethysmography (iPPG), laser Doppler, radio frequency (RF), thermal imaging (TI), optical fiber sensing and piezoelectric sensor. IPPG measures physiological parameters by using video images that record the subtle skin color changes consistent with cardiac-synchronous blood volume changes in subcutaneous arteries and capillaries. Laser Doppler obtained the information on blood flow by analyzing the spectral components of backscattered light from the illuminated tissues’ surface. RF is based on Doppler shift caused by the periodic movement of the chest wall induced by respiration and heartbeat. TI measures vital signs by detecting electromagnetic radiation emitted by blood flow. The working principle of optical fiber sensor is to detect the change of light properties caused by the interaction between the measured physiological parameter and the entering light. Piezoelectric sensors are based on the piezoelectric effect of dielectrics. All these pervasive technologies are noninvasive, mobile, and can detect physiological parameters related to atherosclerosis screening.
动脉粥样硬化筛查通过在致命血管事件发生前评估动脉粥样硬化程度,帮助医学模式从治疗医学转变为预防医学。普及筛查强调动脉粥样硬化监测,具有易于访问、快速处理和高级计算功能。在这项工作中,我们介绍了五种尖端的普适技术,包括成像光电体积描记术(iPPG)、激光多普勒、射频(RF)、热成像(TI)、光纤传感和压电传感器。IPPG通过使用视频图像来测量生理参数,视频图像记录了与皮下动脉和毛细血管中心脏同步血容量变化一致的细微肤色变化。激光多普勒通过分析照射组织表面后向散射光的光谱成分,获得了血流信息。射频是基于呼吸和心跳引起的胸壁周期性运动引起的多普勒频移。TI通过检测血液流动发出的电磁辐射来测量生命体征。光纤传感器的工作原理是检测测量的生理参数与入射光之间的相互作用引起的光特性的变化。压电传感器是基于电介质的压电效应。所有这些普及的技术都是无创的、可移动的,并且可以检测与动脉粥样硬化筛查相关的生理参数。
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引用次数: 2
Review of Eye Tracking Metrics Involved in Emotional and Cognitive Processes 情绪和认知过程中的眼动追踪指标综述
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-17 DOI: 10.1109/RBME.2021.3066072
Vasileios Skaramagkas;Giorgos Giannakakis;Emmanouil Ktistakis;Dimitris Manousos;Ioannis Karatzanis;Nikolaos S. Tachos;Evanthia Tripoliti;Kostas Marias;Dimitrios I. Fotiadis;Manolis Tsiknakis
Eye behaviour provides valuable information revealing one’s higher cognitive functions and state of affect. Although eye tracking is gaining ground in the research community, it is not yet a popular approach for the detection of emotional and cognitive states. In this paper, we present a review of eye and pupil tracking related metrics (such as gaze, fixations, saccades, blinks, pupil size variation, etc.) utilized towards the detection of emotional and cognitive processes, focusing on visual attention, emotional arousal and cognitive workload. Besides, we investigate their involvement as well as the computational recognition methods employed for the reliable emotional and cognitive assessment. The publicly available datasets employed in relevant research efforts were collected and their specifications and other pertinent details are described. The multimodal approaches which combine eye-tracking features with other modalities (e.g. biosignals), along with artificial intelligence and machine learning techniques were also surveyed in terms of their recognition/classification accuracy. The limitations, current open research problems and prospective future research directions were discussed for the usage of eye-tracking as the primary sensor modality. This study aims to comprehensively present the most robust and significant eye/pupil metrics based on available literature towards the development of a robust emotional or cognitive computational model.
眼睛行为提供了有价值的信息,揭示了一个人更高的认知功能和情感状态。尽管眼动追踪在研究界越来越受欢迎,但它还不是检测情绪和认知状态的流行方法。在本文中,我们综述了用于检测情绪和认知过程的眼睛和瞳孔跟踪相关指标(如凝视、注视、扫视、眨眼、瞳孔大小变化等),重点关注视觉注意力、情绪唤起和认知工作量。此外,我们还研究了他们的参与以及用于可靠情绪和认知评估的计算识别方法。收集了相关研究工作中使用的公开数据集,并描述了它们的规格和其他相关细节。还调查了将眼睛跟踪特征与其他模态(如生物信号)以及人工智能和机器学习技术相结合的多模态方法的识别/分类准确性。讨论了眼动追踪作为主要传感器模式的局限性、当前开放的研究问题和未来的研究方向。本研究旨在根据现有文献,全面呈现最稳健和最重要的眼睛/瞳孔指标,以开发稳健的情绪或认知计算模型。
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引用次数: 50
What Ultrasound Can and Cannot Do in Implantable Medical Device Communications 超声在植入式医疗器械通信中能做什么和不能做什么
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-13 DOI: 10.1109/RBME.2021.3080087
Banafsaj Jaafar;Jeff Neasham;Patrick Degenaar
Modern Active Medical Implantable Devices require communications to transmit information to the outside world or other implantable sub-systems. This can include physiological data, diagnostics, and parameters to optimise the therapeutic protocol. The available options are to use optical, radiofrequency, or ultrasonic communications. However, in all cases, transmission becomes more difficult with deeper transmission through tissue. Challenges include absorption and scattering by tissue, and the need to ensure there are no undesirable heating effects. As such, this paper aims to review research progress in using ultrasound as an alternative for deep tissue communications. We provide an empirical review of the technology and communication protocols that different groups have used, as well as comparing the implications in terms of penetration depth, implant size, and data rate. We conclude that this technique has promise for deeper implants and for intrabody communications between implantable devices (intrabody networks).
现代有源医疗植入式设备需要通信来将信息传输到外部世界或其他植入式子系统。这可以包括生理数据、诊断和参数,以优化治疗方案。可用的选择是使用光学、射频或超声波通信。然而,在所有情况下,通过组织进行更深层次的传播会变得更加困难。挑战包括被组织吸收和散射,以及需要确保没有不希望的加热效应。因此,本文旨在回顾使用超声波作为深层组织通信替代方案的研究进展。我们对不同群体使用的技术和通信协议进行了实证审查,并比较了其在穿透深度、植入物大小和数据速率方面的影响。我们得出的结论是,这项技术有望用于更深层次的植入和可植入设备之间的体内通信(体内网络)。
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引用次数: 6
Emerging Wearable Interfaces and Algorithms for Hand Gesture Recognition: A Survey 新兴的手势识别可穿戴界面和算法综述
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-07 DOI: 10.1109/RBME.2021.3078190
Shuo Jiang;Peiqi Kang;Xinyu Song;Benny P.L. Lo;Peter B. Shull
Hands are vital in a wide range of fundamental daily activities, and neurological diseases that impede hand function can significantly affect quality of life. Wearable hand gesture interfaces hold promise to restore and assist hand function and to enhance human-human and human-computer communication. The purpose of this review is to synthesize current novel sensing interfaces and algorithms for hand gesture recognition, and the scope of applications covers rehabilitation, prosthesis control, exoskeletons for augmentation, sign language recognition, human-computer interaction, and user authentication. Results showed that electrical, mechanical, acoustical/vibratory, and optical sensing were the primary input modalities in gesture recognition interfaces. Two categories of algorithms were identified: 1) classification algorithms for predefined, fixed hand poses and 2) regression algorithms for continuous finger and wrist joint angles. Conventional machine learning algorithms, including linear discriminant analysis, support vector machines, random forests, and non-negative matrix factorization, have been widely used for a variety of gesture recognition applications, and deep learning algorithms have more recently been applied to further facilitate the complex relationship between sensor signals and multi-articulated hand postures. Future research should focus on increasing recognition accuracy with larger hand gesture datasets, improving reliability and robustness for daily use outside of the laboratory, and developing softer, less obtrusive interfaces.
手在广泛的基本日常活动中至关重要,阻碍手功能的神经系统疾病会严重影响生活质量。可穿戴手势界面有望恢复和辅助手部功能,增强人机交流。这篇综述的目的是综合当前用于手势识别的新型传感接口和算法,应用范围包括康复、假体控制、用于增强的外骨骼、手语识别、人机交互和用户身份验证。结果表明,电气、机械、声学/振动和光学传感是手势识别界面中的主要输入模式。确定了两类算法:1)预定义的固定手姿势的分类算法和2)连续手指和手腕关节角度的回归算法。传统的机器学习算法,包括线性判别分析、支持向量机、随机森林和非负矩阵因子分解,已被广泛用于各种手势识别应用,最近,深度学习算法被应用于进一步促进传感器信号和多关节手姿势之间的复杂关系。未来的研究应侧重于通过更大的手势数据集提高识别精度,提高实验室外日常使用的可靠性和稳健性,并开发更柔软、不那么突兀的界面。
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引用次数: 56
Lower-Limb Medical and Rehabilitation Exoskeletons: A Review of the Current Designs 下肢医疗和康复外骨骼:当前设计综述
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-07 DOI: 10.1109/RBME.2021.3078001
Alberto Plaza;Mar Hernandez;Gonzalo Puyuelo;Elena Garces;Elena Garcia
Medical and rehabilitation exoskeletons are being increasingly considered by therapists when choosing a treatment for individuals affected by lower limb impairments. Although all such exoskeletons seem to provide similar features and performance, there are, in practice, significant differences among them in terms of maximum walking speed, maximum torque, weight, autonomy, interaction with the user, or even the way to use it. In this review, the state of the art of the main commercial exoskeletons is described, while analyzing their properties, advantages, and disadvantages. Three groups are considered: complete exoskeletons, partial exoskeletons and open lines of research. A comparative analysis between them is performed while considering the main scientific and technical aspects to be improved. In conclusion to this analysis, the balance between feasibility and innovation in exoskeletons development is a design challenge. Commercial exoskeletons must fulfil standards whilst ensuring their safety and robustness. However, achieving a new generation of exoskeletons means a need to implement new hardware paradigms, and to enhance control strategies focused on assist-as-needed scheme. Finally, some aspects to improve current designs of the exoskeleton are presented.
治疗师在为下肢损伤患者选择治疗方法时,越来越多地考虑使用医疗和康复外骨骼。尽管所有这些外骨骼似乎都提供了相似的功能和性能,但在实践中,它们在最大行走速度、最大扭矩、重量、自主性、与用户的互动,甚至使用方式方面存在显著差异,以及缺点。考虑了三组:完整外骨骼、部分外骨骼和开放式研究线。在考虑需要改进的主要科学技术方面的同时,对它们进行了比较分析。总之,外骨骼开发的可行性和创新性之间的平衡是一个设计挑战。商用外骨骼必须符合标准,同时确保其安全性和坚固性。然而,实现新一代外骨骼意味着需要实现新的硬件模式,并增强专注于按需辅助方案的控制策略。最后,提出了改进外骨骼设计的一些方面。
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引用次数: 23
2021 Index IEEE Reviews in Biomedical Engineering Vol. 14 2021生物医学工程IEEE评论索引第14卷
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-03-05 DOI: 10.1109/RBME.2021.3061839
This index covers all technical items - papers, correspondence, reviews, etc. - that appeared in this periodical during the year, and items from previous years that were commented upon or corrected in this year. Departments and other items may also be covered if they have been judged to have archival value. The Author Index contains the primary entry for each item, listed under the first author's name. The primary entry includes the co-authors' names, the title of the paper or other item, and its location, specified by the publication abbreviation, year, month, and inclusive pagination. The Subject Index contains entries describing the item under all appropriate subject headings, plus the first author's name, the publication abbreviation, month, and year, and inclusive pages. Note that the item title is found only under the primary entry in the Author Index.
该索引涵盖了本期刊当年出现的所有技术项目——论文、信件、评论等,以及本年度评论或更正的前几年的项目。如果部门和其他项目被判定具有档案价值,也可以涵盖这些项目。作者索引包含每个项目的主要条目,以第一作者的名字列出。主要条目包括合著者的姓名、论文或其他项目的标题及其位置,由出版物缩写、年份、月份和包含页码指定。主题索引包含在所有适当主题标题下描述该项目的条目,加上第一作者的姓名、出版物缩写、月份和年份,以及包含在内的页面。请注意,项目标题仅在作者索引的主条目下找到。
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引用次数: 0
Neuromuscular Controller Models for Quantifying Standing Balance in Older People: A Systematic Review 用于量化老年人站立平衡的神经肌肉控制器模型:系统综述
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-02-08 DOI: 10.1109/RBME.2021.3057673
Fredrik Olsson;Kjartan Halvorsen;Anna Cristina Åberg
Objective quantification of the balancing mechanisms in humans is strongly needed in health care of older people, yet is largely missing among current clinical balance assessment methods. Hence, the main goal of this literature review is to identify methods that have the potential to meet that need. We searched in the PubMed and IEEE Xplore databases using predefined criteria, screened 1064 articles, and systematically reviewed and categorized methods from 73 studies that deal with identification of neuromuscular controller models of human upright standing from empirical data. These studies were then analyzed with the particular aim to understand to what degree such methods would be useful solutions for assessing the balance of older individuals aged above 60 years. The 16 studies that included an older subject population were especially examined with this in mind. The majority of the reviewed articles focused on research questions related to the general function of human balance control rather than clinical applicability. Further efforts need to be made to adapt these methods for more accessible and mobile technologies and to ensure that the outcomes are valid for balance assessment of a general older population.
在老年人的医疗保健中,迫切需要对人体平衡机制进行客观量化,但在目前的临床平衡评估方法中,这一点在很大程度上是缺失的。因此,本文献综述的主要目标是确定有可能满足这一需求的方法。我们使用预定义的标准在PubMed和IEEE Xplore数据库中进行了搜索,筛选了1064篇文章,并系统地回顾和分类了73项研究中的方法,这些研究涉及从经验数据中识别人类直立的神经肌肉控制器模型。然后对这些研究进行分析,特别是为了了解这些方法在多大程度上是评估60岁以上老年人平衡的有用解决方案。考虑到这一点,对包括老年受试者群体在内的16项研究进行了特别检查。大多数综述文章集中在与人类平衡控制的一般功能相关的研究问题上,而不是临床适用性。需要进一步努力,使这些方法适应更容易获得和移动的技术,并确保结果对一般老年人口的平衡评估有效。
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引用次数: 4
Information and Communication Theoretical Understanding and Treatment of Spinal Cord Injuries: State-of-The-Art and Research Challenges 信息与通信理论对脊髓损伤的理解和治疗:最新技术和研究挑战
IF 17.6 1区 工程技术 Q1 ENGINEERING, BIOMEDICAL Pub Date : 2021-02-02 DOI: 10.1109/RBME.2021.3056455
Ozgur B. Akan;Hamideh Ramezani;Meltem Civas;Oktay Cetinkaya;Bilgesu A. Bilgin;Naveed A. Abbasi
Among the various key networks in the human body, the nervous system occupies central importance. The debilitating effects of spinal cord injuries (SCI) impact a significant number of people throughout the world, and to date, there is no satisfactory method to treat them. In this paper, we review the major treatment techniques for SCI that include promising solutions based on information and communication technology (ICT) and identify the key characteristics of such systems. We then introduce two novel ICT-based treatment approaches for SCI. The first proposal is based on neural interface systems (NIS) with enhanced feedback, where the external machines are interfaced with the brain and the spinal cord such that the brain signals are directly routed to the limbs for movement. The second proposal relates to the design of self-organizing artificial neurons (ANs) that can be used to replace the injured or dead biological neurons. Apart from SCI treatment, the proposed methods may also be utilized as enabling technologies for neural interface applications by acting as bio-cyber interfaces between the nervous system and machines. Furthermore, under the framework of Internet of Bio-Nano Things (IoBNT), experience gained from SCI treatment techniques can be transferred to nano communication research.
在人体的各种关键网络中,神经系统占据着核心地位。脊髓损伤(SCI)的衰弱影响着全世界相当多的人,到目前为止,还没有令人满意的治疗方法。在本文中,我们回顾了SCI的主要治疗技术,包括基于信息和通信技术(ICT)的有前景的解决方案,并确定了这些系统的关键特征。然后,我们介绍了两种新的基于ICT的SCI治疗方法。第一个方案是基于具有增强反馈的神经接口系统(NIS),其中外部机器与大脑和脊髓接口,使得大脑信号直接路由到肢体进行运动。第二项提案涉及自组织人工神经元(AN)的设计,可用于替换受伤或死亡的生物神经元。除了SCI治疗外,所提出的方法还可以通过充当神经系统和机器之间的生物网络接口,作为神经接口应用的使能技术。此外,在生物纳米物联网(IoBNT)的框架下,从SCI治疗技术中获得的经验可以转移到纳米通信研究中。
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引用次数: 10
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IEEE Reviews in Biomedical Engineering
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