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Substance-Induced Psychosis in the Geriatric Population: Overview on Screening and Treatment 老年人群中物质诱发的精神病:筛查和治疗综述
Q4 Medicine Pub Date : 2021-07-01 DOI: 10.33181/13045
Chloe Yeung, Joshua Raven, Abdul Brula
As our elderly population represents an increasing percentage of the overall population, more healthcare resources are spent treating this population. One of the overlooked issues is substance use in this population and its complications. This population is often not forthcoming with psychoactive medical issues, yet many of them came into adulthood in a time when substance use was widespread. This article will discuss the epidemiology of this population, a case of substance-induced persecutory delusion and the availability of screening methods and treatment options.
由于我们的老年人口在总人口中所占的比例越来越高,因此需要花费更多的医疗资源来治疗这一人群。其中一个被忽视的问题是这一人群的药物使用及其并发症。这一群体通常不会出现精神医学问题,但他们中的许多人在药物使用广泛的时期进入成年。本文将讨论这一人群的流行病学、一例物质诱导的迫害妄想症以及筛查方法和治疗方案的可用性。
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引用次数: 0
Ingrown Toenail Management Ingown Toenail Management
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13035
Oms-Iv Asma Ghafoor, Hamza Paracha, Dovrat Goldstein
Ingrown toenails are a common condition in general medicine and dermatology, and they occur when the nail curves inward and pierces the nail fold. Symptoms include pain in the affected toe, erythema and edema. The diagnosis is made clinically and, if left untreated, ingrown toenails can lead to infections and even cellulitis and osteomyelitis. Conservative treatments involve clipping on the spicule and topical antibiotics. However, the mainstay of treatment is matricectomy to reduce the recurrence rate. The risk of ingrown toenail development can be reduced by wearing proper footwear, keeping toenails cut straight and overall foot hygiene. Ingrown toenails can affect various patient populations but are more prevalent in males, young adolescents and pregnant patients. Risk factors include obesity, diabetes, improper toenail clipping and improper footwear. This review explores the clinical manifestations of ingrown toenails, along with their diagnosis and treatment, providing a concise review for physicians to accurately identify and effectively treat patients with ingrown toenails or their resultant complications.
脚趾甲嵌甲是普通医学和皮肤病学中的一种常见疾病,当指甲向内弯曲并刺穿指甲褶皱时就会发生。症状包括脚趾疼痛、红斑和水肿。诊断是临床上做出的,如果不及时治疗,向内生长的脚趾甲会导致感染,甚至蜂窝组织炎和骨髓炎。保守的治疗方法包括修剪刺针和局部使用抗生素。然而,主要的治疗方法是基质切除术以降低复发率。脚趾甲向内生长的风险可以通过穿合适的鞋子、保持脚趾甲的平直和整体足部卫生来降低。脚趾甲会影响不同的患者群体,但在男性、青少年和孕妇中更为普遍。危险因素包括肥胖、糖尿病、脚趾甲修剪不当和鞋类不当。这篇综述探讨了脚趾甲向内生长的临床表现及其诊断和治疗,为医生准确识别和有效治疗脚趾甲内生长或由此产生的并发症提供了简明的综述。
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引用次数: 1
The Rule of Three 三的法则
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13031
DO David Abend
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引用次数: 0
Physician Beliefs Concerning Structural and Institutional Racism in Health Care 医生对医疗保健中结构性和制度性种族主义的看法
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13032
DO William Ciurylo, Carol A. Brenner, D. Thieme
Perceived discrimination in medical settings remains prevalent within the U.S. health care system. However, the details of these experiences and their associations with perceived quality of care are not well understood. This study evaluates any potential difference in African Americans' systemic health care discrimination and Latinx perceived by African American and Latinx patients and physicians. The New England physician alumni from the University of New England College of Osteopathic Medicine were sent surveys. Two hundred fifty-one practicing physicians' responses to the 2018 study address their beliefs toward African Americans and Latinx' racism within the health care system. High scores indicate more significant perceived discrimination among these groups. Physicians have lower discriminatory belief scores across gender, patient racial distribution and specialty.
在美国医疗保健系统中,医疗环境中的明显歧视仍然普遍存在。然而,这些经历的细节以及它们与感知到的护理质量的联系还没有得到很好的理解。本研究评估了非裔美国人和拉丁裔患者和医生对非裔美国人和拉丁裔美国人的系统性卫生保健歧视的潜在差异。来自新英格兰大学骨科医学院的新英格兰医生校友接受了调查。251名执业医生对2018年研究的回应涉及他们对医疗保健系统内非洲裔美国人和拉丁裔种族主义的看法。分数越高,表明在这些群体中感受到的歧视越明显。医生在性别、患者种族分布和专业方面的歧视性信念得分较低。
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引用次数: 0
The Osteopathic Approach to Treating Depression in Children and Adolescents 整骨疗法治疗儿童和青少年抑郁症
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13033
Oms-Iii Ravi Chinsky, Domin Chan
Evidence confirms that children and adolescents can experience the whole spectrum of mood disorders and suffer from the significant morbidity and mortality associated with them. Effective treatment often relies on physicians developing advanced communication skills with their patients. Enhanced communication will help decipher the etiology of the patient’s depression and, in addition to serotonin-regulating medications, will optimize treatment. Osteopathic medicine offers an effective treatment model through osteopathic manipulative treatment (OMT) because of the inseparability of physical and mental health. Osteopathic medicine takes a holistic view in which somatic, visceral and psychological dysfunction are united. Thus, physicians who incorporate OMT into their practice will help treat psychopathologies, such as depression and its accompanying somatic dysfunctions. This paper discusses the epidemiology of depression, the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) depression criteria, screening algorithms, current treatment protocols, osteopathic considerations to treating depression, and lastly, OMT and its role in treatment.
有证据证实,儿童和青少年可能会经历各种情绪障碍,并遭受与之相关的严重发病率和死亡率。有效的治疗通常依赖于医生与患者发展先进的沟通技巧。加强沟通将有助于解读患者抑郁症的病因,除了血清素调节药物外,还将优化治疗。由于身心健康的不可分割性,整骨医学通过整骨手法治疗(OMT)提供了一种有效的治疗模式。骨病医学是将躯体功能障碍、内脏功能障碍和心理功能障碍统一起来的一种整体观。因此,将OMT纳入实践的医生将有助于治疗精神病理学,如抑郁症及其伴随的躯体功能障碍。本文讨论了抑郁症的流行病学、《精神障碍诊断与统计手册》第5版(DSM-5)抑郁症标准、筛查算法、当前治疗方案、治疗抑郁症的整骨注意事项,以及OMT及其在治疗中的作用。
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引用次数: 0
New-Onset Diabetic Ketoacidosis Secondary to Nivolumab Therapy in a Patient with Primary Central Nervous System Lymphoma Nivolumab治疗原发性中枢神经系统淋巴瘤继发的新发糖尿病酮症酸中毒
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13037
Do Pgy Christine Feng, DO Pavel Kibrik, C. Castañeda, Face Gurdeep Singh
Introduction: Inhibitors of programmed cell death receptor (PD-1) and its ligand (PD-L1), such as nivolumab and pembrolizumab, confer anti-autoimmune activities and are therefore approved for anti-cancer therapy. Their mode of action removes autoimmunity checkpoints, thus increasing the risk of immune-related adverse events. Case Presentation: This report describes a clinical case of life-threatening diabetic ketoacidosis (DKA) in a patient after long-term nivolumab administration to treat primary central nervous system lymphoma (PCNSL). The patient presented to the emergency department (ED) with symptoms of fatigue, along with nausea and vomiting for two days; laboratory testing revealed significant hyperglycemia (glucose 673 mg/dL), elevated anion gap (>27), metabolic acidosis, ketonemia, glucosuria and ketonuria, findings of which were consistent with DKA. Given no personal history of diabetes mellitus or other autoimmune conditions and additional tests ruling out alternative causes, the patient was suspected of having newly-onset DKA secondary to nivolumab treatment. Management & Outcome: The patient was treated with fluids, electrolytes replenishments and insulin drip, which closed the anion gap and normalized electrolytes. She was transitioned to subcutaneous insulin. The patient recovered well and was discharged on Metformin and longacting insulin, with close follow-up with endocrinology and oncology. Discussion: Autoimmune endocrinopathies induced by checkpoint inhibitors for cancer treatment have been reported in the past. Newly-onset hyperglycemia and DKA are common autoimmunemediated side effects of checkpoint inhibitor uses in patients without prior history of diabetes mellitus. Clinicians should be aware to prevent this potentially life-threatening condition.
导读:程序性细胞死亡受体(PD-1)及其配体(PD-L1)的抑制剂,如纳武单抗和派姆单抗,具有抗自身免疫活性,因此被批准用于抗癌治疗。它们的作用模式消除了自身免疫检查点,从而增加了免疫相关不良事件的风险。病例介绍:本报告描述了一位长期服用纳武单抗治疗原发性中枢神经系统淋巴瘤(PCNSL)的患者发生危及生命的糖尿病酮症酸中毒(DKA)的临床病例。患者以疲劳症状就诊于急诊科(ED),并伴有恶心和呕吐2天;实验室检测显示高血糖(葡萄糖673 mg/dL),阴离子间隙升高(bbb27),代谢性酸中毒,酮血症,糖尿和酮尿,这些发现与DKA一致。鉴于没有糖尿病或其他自身免疫性疾病的个人病史,以及排除其他原因的其他检查,该患者被怀疑是纳武单抗治疗后继发的新发DKA。治疗和结果:患者给予补液、补充电解质和胰岛素滴注,使阴离子间隙缩小,电解质正常化。她改用皮下注射胰岛素。患者恢复良好,出院时给予二甲双胍和长效胰岛素治疗,并密切随访内分泌科和肿瘤科。讨论:在癌症治疗中,检查点抑制剂诱导的自身免疫性内分泌病变在过去已有报道。新发高血糖和DKA是无糖尿病史患者使用检查点抑制剂时常见的自身免疫介导的副作用。临床医生应该注意预防这种可能危及生命的疾病。
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引用次数: 1
Facial Rash with Eye Swelling 面部皮疹伴眼睛肿胀
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13038
Do Mba Facoep Lindsay Tjiattas-Saleski, Oms-Iii Erik Krueger
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引用次数: 0
What the Past Has Taught Us: Best Practices for OFPs to Manage Stress During a Virus Outbreak 过去教会了我们什么:OFP在病毒爆发期间管理压力的最佳实践
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13034
Do Mms Tina Chuong, Do Mph Karen Lazarus, DO Meera Shah
OFPs and other health care professionals experience increased rates of stress, anxiety, fatigue and burnout in the face of pandemics. Historically, this has been observed with other pandemics, such as the influenza pandemic, HIV/AIDS, SARS, H1N1, Ebola virus disease and, more recently, COVID-19. Research about physician wellbeing during prior pandemics has informed recent practices and provides more guidance on how larger health care entities can provide for employees and how physicians can care for themselves. Here, we explore best practices for emotional/spiritual wellbeing, physical wellbeing, maintaining a healthy family life and wellness during a virus outbreak.
面对流行病,OFP和其他医疗保健专业人员的压力、焦虑、疲劳和倦怠率增加。从历史上看,这在其他流行病中也有观察到,如流感大流行、艾滋病毒/艾滋病、SARS、H1N1、埃博拉病毒疾病,以及最近的新冠肺炎。关于先前流行病期间医生健康状况的研究为最近的实践提供了信息,并为大型医疗保健实体如何为员工提供服务以及医生如何照顾自己提供了更多指导。在这里,我们探索了在病毒爆发期间实现情感/精神健康、身体健康、维持健康家庭生活和身心健康的最佳实践。
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引用次数: 0
Multisystem Inflammatory Syndrome in Infant with Negative SARS-CoV-2 RT-PCR and Antibodies 严重急性呼吸系统综合征冠状病毒2型RT-PCR和抗体阴性婴儿的多系统炎症综合征
Q4 Medicine Pub Date : 2021-05-01 DOI: 10.33181/13036
Md Faap Facop Hanna S. Sahhar, DO Karly Derwitz, DO Erica Rubin
Since the declaration of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in March 2020 by the World Health Organization (WHO), there has been an emergence of a new syndrome termed multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19. MIS-C is defined by the presence of fever, systemic inflammation and multiorgan dysfunction in association with SARS-CoV-2 infection or COVID-19 exposure. Knowledge of this syndrome’s presentation and pathophysiology is constantly evolving as more cases are reported in the literature. This case identifies a 3-month-old patient who tested negative for SARS-CoV-2 antigen, reverse transcriptase polymerase chain reaction (RT-PCR) and antibodies but qualified for MIS-C diagnosis. To the best of our knowledge and through extensive research at the time of diagnosing and reporting this condition to the healthcare authorities, we report the youngest pediatric patient with MIS-C diagnosis. We document this case to contribute to further understanding the variable manifestations of MIS-C and the importance of early diagnosis and treatment with intravenous immunoglobulin (IVIG).
自世界卫生组织(世界卫生组织)于2020年3月宣布严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)大流行以来,出现了一种称为与新冠肺炎相关的儿童多系统炎症综合征(MIS-C)的新综合征。MIS-C是指与SARS-CoV-2感染或新冠肺炎暴露相关的发热、全身炎症和多器官功能障碍。随着文献中报道的病例越来越多,对该综合征的表现和病理生理学的认识也在不断发展。该病例确定了一名3个月大的患者,其严重急性呼吸系统综合征冠状病毒2型抗原、逆转录聚合酶链式反应(RT-PCR)和抗体检测呈阴性,但符合MIS-C诊断条件。据我们所知,在诊断和向医疗当局报告这种情况时,通过广泛的研究,我们报告了最年轻的儿童MIS-C诊断患者。我们记录了这个病例,以帮助进一步了解MIS-C的各种表现以及静脉注射免疫球蛋白(IVIG)早期诊断和治疗的重要性。
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引用次数: 0
A Rare Cause of Dyspnea 呼吸困难的罕见原因
Q4 Medicine Pub Date : 2021-03-01 DOI: 10.33181/13026
Vinesha Patel Do, David Do
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引用次数: 0
期刊
Osteopathic Family Physician
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