Journal of Stomatology Oral and Maxillofacial Surgery最新文献

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Total Lower Lip and Chin Replantation in a Child Following a Trampoline Accident: A Case Report of Rescue Surgery with Intensive Leech Therapy. 蹦床事故后儿童全下唇及下巴再植一例：强化水蛭治疗的抢救手术。

IF 2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2026-01-07 DOI: 10.1016/j.jormas.2026.102709

V Sounthakith, A Schweitzer-Chaput, A Picard, J Prebot, A Galland, C Neiva-Vaz, R H Khonsari

Lip amputations in children may require urgent microsurgical management. Here we report a salvage procedure with partial survival following lower lip and chin replantation after a trampoline accident. Total amputation was managed with inferior labial artery anastomosis; however, venous drainage was not reestablished, necessitating leech therapy. Despite arterial revisions, 75% of the lip and 25% of the chin were lost by post-operative day 14. Reconstruction with a combined right Karapandzic flap and left Camille Bernard flap was performed one month later, supplemented by mesotherapy and nanofat injections. The outcome was marked by residual microstomia. These injuries are rare in children, often caused by dog bites. Venous anastomosis is frequently unfeasible, with leech therapy critical for drainage. When replantation is partially successful, reconstruction may involve local flaps or free tissue transfers. Microsurgical expertise, access to leech therapy and close collaboration with intensivists are essential for optimizing outcomes.

儿童唇部截肢可能需要紧急显微外科治疗。在此，我们报告一个在蹦床事故后下唇和下巴再植后部分存活的抢救手术。全截肢采用唇下动脉吻合术；然而，静脉引流没有恢复，需要水蛭治疗。尽管动脉修复，术后第14天75%的嘴唇和25%的下巴都消失了。1个月后行右侧Karapandzic皮瓣和左侧Camille Bernard皮瓣联合重建，并辅以化疗和纳米脂肪注射。结果以残留的小口畸形为标志。这些伤害在儿童中很少见，通常是由狗咬伤引起的。静脉吻合通常不可行，水蛭疗法对引流至关重要。当再植部分成功时，重建可能涉及局部皮瓣或游离组织转移。显微外科专业知识、获得水蛭疗法以及与重症医师密切合作对于优化结果至关重要。

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引用次数: 0

Novel De Novo CLCN7 Mutation in Refractory Osteopetrosis-Related Osteomyelitis: A Case Report and Multidisciplinary Therapeutic Dilemmas. 难治性骨质疏松相关骨髓炎的新CLCN7突变：一例报告和多学科治疗困境。

IF 2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2025-12-18 DOI: 10.1016/j.jormas.2025.102686

Yi-Wen Zhang, Qi-Yao Jin, Ming Xu, Jian-Ping Xu, Yu-Cai Zhong, Chong Li, Ke Lu

Background: Osteopetrosis, characterized by impaired osteoclast function and increased bone density, poses significant clinical challenges when complications like mandibular osteomyelitis arise. This report elucidates the clinicoradiographic progression and management of such a case in ADO-II, driven by a novel de novo CLCN7 c.2227C>T (p.R743W) mutation.

Case presentation: A 57-year-old male presented with refractory mandibular osteomyelitis accompanied by facial swelling and trismus. Radiographs revealed mandibular osteolysis, "sandwich vertebrae," and "Erlenmeyer flask" deformities. He had anemia and thrombocytopenia. Sequencing analysis revealed a de novo CLCN7 c.2227C>T (p.R743W) mutation in the patient. Therapeutic measures involved partial splenic artery embolization, administration of intravenous cefuroxime and ornidazole combined with hyperbaric oxygen therapy and pleural drainage. The osteomyelitis persisted due to avascular necrosis in sclerotic bone, despite the adoption of multidisciplinary management.

Conclusions: This case highlights the aggressive phenotype associated with the CLCN7 c.2227C>T (p.R743W) mutation, the importance of early genetic testing and personalized therapeutic strategies.

背景：骨质疏松症以破骨细胞功能受损和骨密度增加为特征，当颌骨骨髓炎等并发症出现时，对临床提出了重大挑战。本报告阐述了由一种新的新发CLCN7 c.2227C>T （p.R743W）突变驱动的ADO-II病例的临床放射学进展和治疗。病例介绍：一名57岁男性，因难治性下颌骨骨髓炎并伴有面部肿胀和咬牙。x线片显示下颌骨骨溶解，“夹心椎体”和“Erlenmeyer烧瓶”畸形。他患有贫血和血小板减少症。测序分析显示患者中有一个新生的CLCN7 c.2227C>T （p.R743W）突变。治疗措施包括部分脾动脉栓塞、静脉注射头孢呋辛和奥硝唑联合高压氧治疗和胸腔引流。尽管采用了多学科治疗，但由于硬化骨的无血管坏死，骨髓炎仍然存在。结论：该病例强调了与CLCN7 c.2227C>T （p.R743W）突变相关的侵袭性表型，以及早期基因检测和个性化治疗策略的重要性。

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引用次数: 0

Artificial intelligence transforms the future of oncology care. 人工智能改变肿瘤治疗的未来。

IF 2.2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-09-01 Epub Date: 2024-05-16 DOI: 10.1016/j.jormas.2024.101915

Archana Behera, Mukesh Kumar Dharmalingam Jothinathan

引用次数: 0

WITHDRAWN: Histomorphometric Image Classifier of Different Grades of Oral Squamous Cell Carcinoma Using Transfer Learning and Convolutional Neural Network 利用迁移学习和卷积神经网络对不同分级的口腔鳞状细胞癌进行组织形态学图像分类

IF 2.2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2024-04-16 DOI: 10.1016/j.jormas.2024.101876

Dr Ayushi Jain, Nitika Gupta, Dr Pooja Sharma, Dr Om Prakash Gupta, Dr Shalini Gupta, Dr Amaresh Kumar Sahoo

This article has been withdrawn at the request of the authors. The Publisher apologizes for any inconvenience this may cause.The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies/article-withdrawal

背景：机器学习是医疗保健领域的一项新兴技术，旨在从根本上改革传统系统，为医疗从业人员提供帮助。口腔癌的组织病理学分析对于病理学家确定其分级至关重要。因此，本研究尝试使用不同的深度学习模型对 OSCC（口腔鳞状细胞癌）患者的各种染色组织样本进行分级：收集了 120 张 OSCC 组织病理学图像数据集，并根据 Broders 的分级系统将其分为分化良好（40 张）、中度分化（40 张）和分化不良（40 张）。CNN（卷积神经网络）架构基于预先训练的神经网络模型VGG16（视觉几何组16）、VGG19（视觉几何组19）、RESNET50（残差网络50）和DENSENET121（密集网络121）模型进行图像分析：在放大 4 倍的情况下，所有四个模型都达到了最高的测试准确率，即 66.67%。DENSENET121 的验证准确率最高，达到 81%。在 10 倍放大率下，RESNET50、VGG19 和 DENSENET121 的测试准确率最高，达到 90.9%，VGG19 的验证准确率最高，达到 83.3%。在 40x 时，RESNET50 和 DENSENET121 的测试准确率最高，达到 70%。RESNET50、VGG16和VGG19的验证准确率相当：在数字成像和计算辅助诊断中借助深度学习对组织进行分级，有助于对口腔癌患者进行及时有效的预后判断和多模式治疗方案，从而减轻病理学家的业务工作量。通过系统评估模型性能和解决过拟合问题，我们开发出了适用于医疗诊断的稳健模型。

引用次数: 0

WITHDRAWN: A comparison of ear amputations replantation techniques. 摘自：耳部截肢再植技术的比较。

IF 2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2023-03-04 DOI: 10.1016/j.jormas.2023.101429

Nicolas Baldini

引用次数: 0

WITHDRAWN: Minocycline hydrochloride combined with invisible and fixed orthodontic treatment improves periodontal health in periodontitis patients by reducing microRNA-146a levels. 撤销：盐酸米诺环素与隐形和固定正畸治疗相结合，通过降低 microRNA-146a 水平改善牙周炎患者的牙周健康。

IF 2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery

Pub Date : 2022-11-04 DOI: 10.1016/j.jormas.2022.11.003

Qin Xie, Duo Li

This article has been withdrawn at the request of the authors. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.

应作者要求，本文已被撤回。出版商对此造成的不便深表歉意。完整的爱思唯尔文章撤稿政策请访问 https://www.elsevier.com/about/our-business/policies/article-withdrawal。

引用次数: 0

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