In this paper, we proposed a new method of signal processing techniques for the application of analyzing four typical lung-sound signals (tracheal breath sounds, vesicular breath sounds, inspiratory and expiratory stridor, and stridor). First, we focus on the estimation method of the sound source number in a lung disease. Second, we calculate the time interval of each sound source signal accurately. Finally, we put the delay time and the number of sound sources as the characteristics, and study the relationships between each pathological lung sound and the characteristics. The innovation of this paper is that utilizing the cepstrum analysis as a new idea to study the pathological diagnosis of lung diseases.
{"title":"The Research of Lung Sound Signals Based on Cepstrum Analysis","authors":"Benjin Wang, L. Miao, H. Dong, Zeguang Zheng","doi":"10.1109/ICBEB.2012.439","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.439","url":null,"abstract":"In this paper, we proposed a new method of signal processing techniques for the application of analyzing four typical lung-sound signals (tracheal breath sounds, vesicular breath sounds, inspiratory and expiratory stridor, and stridor). First, we focus on the estimation method of the sound source number in a lung disease. Second, we calculate the time interval of each sound source signal accurately. Finally, we put the delay time and the number of sound sources as the characteristics, and study the relationships between each pathological lung sound and the characteristics. The innovation of this paper is that utilizing the cepstrum analysis as a new idea to study the pathological diagnosis of lung diseases.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"4 1","pages":"934-938"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80183544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rongrong Zhang, Chunqing Xie, Yayun Zhu, Liangjun Pan, Changying Yang
A DNA-modified electrode was fabricated by the way of electrode modifying, namely the polymerisation-covalently bonding, for studying the recognition of DNA to heme protein. Electrochemical Impedence Resistance (EIS) showed that electron transfer resistance increased with the adding of Hemoglobin (Hb) and Cytochrome c (Cyt c). Reaction constant of Hb and DNA is K=1.13×105 L-mol-1, and K=4.08×105 L-mol-1 for Cyt c, indicating that DNA-modified electrode can well recognize Hb and Cyt c.
{"title":"The Electrochemical Impedance Recognition for Two Heme Proteins on dsDNA/PGA/GCE","authors":"Rongrong Zhang, Chunqing Xie, Yayun Zhu, Liangjun Pan, Changying Yang","doi":"10.1109/ICBEB.2012.13","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.13","url":null,"abstract":"A DNA-modified electrode was fabricated by the way of electrode modifying, namely the polymerisation-covalently bonding, for studying the recognition of DNA to heme protein. Electrochemical Impedence Resistance (EIS) showed that electron transfer resistance increased with the adding of Hemoglobin (Hb) and Cytochrome c (Cyt c). Reaction constant of Hb and DNA is K=1.13×10<sup>5</sup> L-mol<sup>-1</sup>, and K=4.08×10<sup>5</sup> L-mol<sup>-1</sup> for Cyt c, indicating that DNA-modified electrode can well recognize Hb and Cyt c.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"107 1","pages":"925-928"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83199090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A novel modified sequencing batch reactor was proposed to treat municipal wastewater. The modified SBR had a special structure consisting of 4 tanks with different anaerobic/anoxic/aerobic function. A pilot-scale modified SBR process was researched to treat urban wastewater. The effluent TN was 10 mg/L. The TN removal efficiency was 58%. The NH4+-N removal efficiency was 98%. The average effluent NH4+-N was lower than 0.8 mg/L. The result showed the novel modified SBR was advantageous for nitrification bacteria growth. The TP removal efficiency was 81%. The average effluent TP concentration was less than 0.75 mg/L. The effluent TP concentration below 0.75 mg/L was got on 95% of the operational days. The result showed the novel modified SBR was advantageous for PAO bacteria growth.
{"title":"A Pilot-scale Experimental Research on Nutrient Matter Removal in a Modified SBR","authors":"Jun Yu Li, Li-min Wang, Xue-bin Li, Jiong-hui Li","doi":"10.1109/ICBEB.2012.36","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.36","url":null,"abstract":"A novel modified sequencing batch reactor was proposed to treat municipal wastewater. The modified SBR had a special structure consisting of 4 tanks with different anaerobic/anoxic/aerobic function. A pilot-scale modified SBR process was researched to treat urban wastewater. The effluent TN was 10 mg/L. The TN removal efficiency was 58%. The NH4+-N removal efficiency was 98%. The average effluent NH4+-N was lower than 0.8 mg/L. The result showed the novel modified SBR was advantageous for nitrification bacteria growth. The TP removal efficiency was 81%. The average effluent TP concentration was less than 0.75 mg/L. The effluent TP concentration below 0.75 mg/L was got on 95% of the operational days. The result showed the novel modified SBR was advantageous for PAO bacteria growth.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"17 1","pages":"1169-1171"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83393428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A liposome-encapsulated lodide-lodate chemical actinometer has been synthesized to monitor the inactive microorganisms damaged by UV disinfection. Relationship between bio-dosimeter and liposome-encapsulated lodide-lodate chemical actinometer under low pressure UV lamp was investigated. Similar dose rates between chemical actinometer and bio-dosimeter were observed. The particle sizes of liposome-encapsulated lodide-lodate chemical actinometer ranged from 1 to 3 μm. The chemical actinometer after encapsulation by the liposome was concentrated to 7 times by a TOC assay. Results indicate that it is possible to apply the liposome-encapsulated lodide-lodate chemical actinometer in UV water disinfection systems.
{"title":"Studies on Liposome-encapsulated-chemical Actinometer in UV-disinfection by Low Pressure UV Lamp: Bio-chemical Actinometer in UV-Disinfection","authors":"Jinglan Hong, M. Otaki","doi":"10.1109/ICBEB.2012.368","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.368","url":null,"abstract":"A liposome-encapsulated lodide-lodate chemical actinometer has been synthesized to monitor the inactive microorganisms damaged by UV disinfection. Relationship between bio-dosimeter and liposome-encapsulated lodide-lodate chemical actinometer under low pressure UV lamp was investigated. Similar dose rates between chemical actinometer and bio-dosimeter were observed. The particle sizes of liposome-encapsulated lodide-lodate chemical actinometer ranged from 1 to 3 μm. The chemical actinometer after encapsulation by the liposome was concentrated to 7 times by a TOC assay. Results indicate that it is possible to apply the liposome-encapsulated lodide-lodate chemical actinometer in UV water disinfection systems.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"22 1","pages":"1704-1707"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81183891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuping Li, J. Chang, Cheng-mei Liu, X. Xiong, Y. Gong, Zi-ling Li
The previous studies of our team and other researchers have shown that two polysaccharides derived from bulbs of lily aqueous extracts (LP-1, LP-2) can decrease fasting blood glucose concentration in diabetic model animal (in vivo). In the present study, we investigated the effects of LP-1 or LP-2 on cultured pancreatic d-cell tumor-derived cell line HIT-T15 that had undergone oxidative damage. The cell viability, insulin secretion, and intracellular reactive oxygen species (ROS) level were investigated in HIT-T15 cells after LP-, alloxan-, or both-treatment, respectively. The metabolic activity of d-cells was determined by MTT assay while the insulin secretion was detected by ELISA technique. Intracellular ROS was detected by fluorescent spectrophotometry using DCFH-DA. The treatment with LP-1 (>; 0.5 mg/ml) or LP-2 (>; 0.1 mg/ml) could significantly elevated the cell viability compared to untreated normal cells (p 1 mg/ml). Importantly, the viability of cells treated with 10 mg/ml LP-2 were almost restored to the levels of alloxan-untreated cells and completely prevented the lowering of glucose-stimulated insulin release. Our investigation suggested that LP-1 or LP-2 reduced the damage of alloxan-induced HIT-T15 cells through scavenging intracellular ROS level. And these data also provide some information when LP-1 or LP-2 is used as a bioactive component for developing a new anti-diabetic agent.
{"title":"Lily Polysaccharide Prevents Alloxan-induced HIT-T15 Cell Damage by Reducing ROS Generation","authors":"Yuping Li, J. Chang, Cheng-mei Liu, X. Xiong, Y. Gong, Zi-ling Li","doi":"10.1109/ICBEB.2012.264","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.264","url":null,"abstract":"The previous studies of our team and other researchers have shown that two polysaccharides derived from bulbs of lily aqueous extracts (LP-1, LP-2) can decrease fasting blood glucose concentration in diabetic model animal (in vivo). In the present study, we investigated the effects of LP-1 or LP-2 on cultured pancreatic d-cell tumor-derived cell line HIT-T15 that had undergone oxidative damage. The cell viability, insulin secretion, and intracellular reactive oxygen species (ROS) level were investigated in HIT-T15 cells after LP-, alloxan-, or both-treatment, respectively. The metabolic activity of d-cells was determined by MTT assay while the insulin secretion was detected by ELISA technique. Intracellular ROS was detected by fluorescent spectrophotometry using DCFH-DA. The treatment with LP-1 (>; 0.5 mg/ml) or LP-2 (>; 0.1 mg/ml) could significantly elevated the cell viability compared to untreated normal cells (p 1 mg/ml). Importantly, the viability of cells treated with 10 mg/ml LP-2 were almost restored to the levels of alloxan-untreated cells and completely prevented the lowering of glucose-stimulated insulin release. Our investigation suggested that LP-1 or LP-2 reduced the damage of alloxan-induced HIT-T15 cells through scavenging intracellular ROS level. And these data also provide some information when LP-1 or LP-2 is used as a bioactive component for developing a new anti-diabetic agent.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"38 1","pages":"364-367"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81311377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Ying, Xu Zhen-cheng, Guo Qing-wei, L. Xiao-ming, Wang Li, Hong Cheng-yang, Bing Yong-xin
A scoping investigation was carried out to evaluate the occurrence, persistence and fate of a range of pharmaceuticals and personal care products (PPCPs) at different processing points at three full-scale sewage treatment plants (STPs) at Guangdong, South China. The concentrations of 7 pharmaceuticals from non-steroidal anti-inflammatory analgesics and antihyperlipidemics were examined in each treatment stages in STP3. And one anti-biotic was examined the removal efficiencies in three STPs. Salicylic acid was the most abundant analyte in the three STPs influent, up to ppb magnitude, followed by ibuprofen, diclofenac, naproxen, gemfibrozil, mefenamic acid and clofibric acid. The concentration of salicylic acid, ibuprofen, diclofenac, naproxen and gemfibrozil decreased at least by one order of magnitude after biological treatments. Mefenamic acid and clofibric acid were found not apparent removal efficiencies during these stages, which could indicate lower biodegradability. The different results of triclosan (TCS) removal were appeared in three sewage treatment plants, 79.46%, 64.11% and 31.95%, respectively. Now, the existing sewage treatment system only dependent on the activated sludge secondary treatment can not completely remove PPCPs.
{"title":"Occurrence and Elimination of PPCPs in Sewage Treatment Plants, in the Pearl River Delta (PRD), South China","authors":"T. Ying, Xu Zhen-cheng, Guo Qing-wei, L. Xiao-ming, Wang Li, Hong Cheng-yang, Bing Yong-xin","doi":"10.1109/ICBEB.2012.287","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.287","url":null,"abstract":"A scoping investigation was carried out to evaluate the occurrence, persistence and fate of a range of pharmaceuticals and personal care products (PPCPs) at different processing points at three full-scale sewage treatment plants (STPs) at Guangdong, South China. The concentrations of 7 pharmaceuticals from non-steroidal anti-inflammatory analgesics and antihyperlipidemics were examined in each treatment stages in STP3. And one anti-biotic was examined the removal efficiencies in three STPs. Salicylic acid was the most abundant analyte in the three STPs influent, up to ppb magnitude, followed by ibuprofen, diclofenac, naproxen, gemfibrozil, mefenamic acid and clofibric acid. The concentration of salicylic acid, ibuprofen, diclofenac, naproxen and gemfibrozil decreased at least by one order of magnitude after biological treatments. Mefenamic acid and clofibric acid were found not apparent removal efficiencies during these stages, which could indicate lower biodegradability. The different results of triclosan (TCS) removal were appeared in three sewage treatment plants, 79.46%, 64.11% and 31.95%, respectively. Now, the existing sewage treatment system only dependent on the activated sludge secondary treatment can not completely remove PPCPs.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"13 1","pages":"1576-1581"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82476981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The silkworm pupa (SWP) is known for their nutritional value of high protein. In China, the production of protein of silkworm pupae (PSP) is very high because of the development of silk industry. This study applied the model which already was reported in the literature to the PSP - Alcalase system. It proved that the substrate inhibition existed in this system, and its reaction constants were determined as Km=3.50 g·L-1, k2=251.7 min-1, Ks=94.8 g·L-1, kd=41.4 min-1, c0=3.13×10-4, rmax=16.2 g·L-1·min-1. At last, the experimental data were substituted this kinetic model, the average relative error was only 4.60%. So, it proved that kinetic model was reasonable, and the kinetic equation could model the hydrolysis process of PSP-Alcalase.
{"title":"Kinetic Model of Enzymatic Hydrolysis of Protein about the Protein of Silkworm Pupae -- Alcalase System","authors":"Zhongxing Zhao, Dankui Liao, Jianhua Sun, Z. Tong, Kelin Huang, Guosong Sun, Zhihong Wu","doi":"10.1109/ICBEB.2012.262","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.262","url":null,"abstract":"The silkworm pupa (SWP) is known for their nutritional value of high protein. In China, the production of protein of silkworm pupae (PSP) is very high because of the development of silk industry. This study applied the model which already was reported in the literature to the PSP - Alcalase system. It proved that the substrate inhibition existed in this system, and its reaction constants were determined as K<sub>m</sub>=3.50 g·L<sup>-1</sup>, k<sub>2</sub>=251.7 min<sup>-1</sup>, K<sub>s</sub>=94.8 g·L<sup>-1</sup>, k<sub>d</sub>=41.4 min<sup>-1</sup>, c<sub>0</sub>=3.13×10<sup>-4</sup>, r<sub>max</sub>=16.2 g·L<sup>-1</sup>·min<sup>-1</sup>. At last, the experimental data were substituted this kinetic model, the average relative error was only 4.60%. So, it proved that kinetic model was reasonable, and the kinetic equation could model the hydrolysis process of PSP-Alcalase.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"19 1","pages":"356-359"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82525639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To study the efficacy of one regimes of commonly used chemotherapy( cyclophosphamide + adriamycin+ 5-fluorouracil, CAF) and its relationship with estrogen receptor(ER), thymidylate synthase (TS) for breast carcinoma. Methods The inhibition rates of CAF with primary cell culture were observed by MTT method in 111 cases of breast carcinoma. The expressions of TS, ER in 111 cases of breast cancer and 38 cases of adenofibroma were examined by streptavidin-perosidase immunohistochemistry method. Results Positive rates of TS and ER were higher in breast carcinoma than that in adenofibroma. Expression of ER was related to histological type in breast carcinoma (P<;0.05). Expressions rates of TS and ER were related to lymph node metastasis (P<;0.05). The sensitive rate of CAF chemotherapy protocols was 44.1%. There was relationship between expressions of TS, ER and sensitive rate of CAF chemotherapy protocols. Conclusion: The overexpressions of TS, ER may play an important role in the carcinogenesis of breast cancer. Detection of TS, ER expressions in breast carcinoma may direct to choose CAF chemotherapy.
{"title":"Correlation between Expressions of Estrogen Receptor, Thymidylate Synthase and CAF Regime Sensibility in Breast Carcinoma","authors":"Xiaoli Zhang, Linxi Zhang","doi":"10.1109/ICBEB.2012.117","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.117","url":null,"abstract":"To study the efficacy of one regimes of commonly used chemotherapy( cyclophosphamide + adriamycin+ 5-fluorouracil, CAF) and its relationship with estrogen receptor(ER), thymidylate synthase (TS) for breast carcinoma. Methods The inhibition rates of CAF with primary cell culture were observed by MTT method in 111 cases of breast carcinoma. The expressions of TS, ER in 111 cases of breast cancer and 38 cases of adenofibroma were examined by streptavidin-perosidase immunohistochemistry method. Results Positive rates of TS and ER were higher in breast carcinoma than that in adenofibroma. Expression of ER was related to histological type in breast carcinoma (P<;0.05). Expressions rates of TS and ER were related to lymph node metastasis (P<;0.05). The sensitive rate of CAF chemotherapy protocols was 44.1%. There was relationship between expressions of TS, ER and sensitive rate of CAF chemotherapy protocols. Conclusion: The overexpressions of TS, ER may play an important role in the carcinogenesis of breast cancer. Detection of TS, ER expressions in breast carcinoma may direct to choose CAF chemotherapy.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"5 1","pages":"123-126"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82532119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to investigate the clinical outcomes of human brain dielectric properties in order to build a human-like brain phantom using simple material. This artificial intelligence human brain was developed according to the dielectric properties of a real human brain. The regions cover grey matter and white matter tissues. Elements used for phantom building demonstrate adequate internal consistency of er (relative permittivity) within 60-80 for a range of frequency from 1-6 GHz. A surprisingly finding, quantity of element sugar is the main reason of affecting the permittivity. The findings give a big step closer for building an artificial human brain without defect.
{"title":"Human Brain Phantom Modeling Based on Relative Permittivity Dielectric Properties","authors":"K. Chew, R. Sudirman, N. Seman, Ching Yee Yong","doi":"10.1109/ICBEB.2012.239","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.239","url":null,"abstract":"This study aims to investigate the clinical outcomes of human brain dielectric properties in order to build a human-like brain phantom using simple material. This artificial intelligence human brain was developed according to the dielectric properties of a real human brain. The regions cover grey matter and white matter tissues. Elements used for phantom building demonstrate adequate internal consistency of er (relative permittivity) within 60-80 for a range of frequency from 1-6 GHz. A surprisingly finding, quantity of element sugar is the main reason of affecting the permittivity. The findings give a big step closer for building an artificial human brain without defect.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"25 1","pages":"817-820"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81159861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. M. S. Serrano, M. A. C. Quevedo, M. de la Iglesia-Vaya, L. Martí-Bonmatí, R. Valenzuela
The management and knowledge extraction system for bioimaging in the cloud (R & D Cloud CEIB) which is proposed in this article will use the services offered by the centralization of bioimaging through Valencian Biobank Medical Imaging (GIMC) as a basis for managing and extracting knowledge from a bioimaging bank, providing that knowledge in the form of services with high added value and expertise to the Electronic Patient History System (HSE), thus bringing the results of R & D to the patient, improving the quality of the information contained therein. R & D Cloud CEIB has four general modules: Search engine (SE), manager of clinical trials (GEBID), anonymizer (ANON) and bioimage knowledge engine (BIKE). The BIKE is the central module and through its sub modules analyzes and generates knowledge to provide to the HSE through services. The technology used in R & D Cloud CEIB is completely based on Open Source. Within the BIKE, we focus on the development of the classifier module (BIKE-Classifier), which aims to establish a method for the extraction of biomarkers for bioimaging and subsequent analysis to obtain a classification in bioimaging available pools following GIMC diagnostic experiences.
bioimaging管理和知识提取系统的云(云CEIB R & D),本文提出了将使用提供的服务集中bioimaging通过瓦伦西亚生物医学成像(GIMC)为基础管理和从bioimaging银行获取知识,为知识服务的形式提供高附加值和专业知识的电子病历系统(HSE),从而使R & D病人的结果,提高其中所含信息的质量。研发云中欧国际工商学院有四大通用模块:搜索引擎(SE)、临床试验管理器(GEBID)、匿名器(ANON)和生物图像知识引擎(BIKE)。BIKE是中心模块，通过其子模块分析和生成知识，通过服务提供给HSE。中欧国际工商学院研发云采用的技术完全基于开源。在BIKE中，我们专注于分类器模块(BIKE- classifier)的开发，该模块旨在建立一种提取生物成像和后续分析的生物标记物的方法，从而根据GIMC诊断经验在生物成像可用池中获得分类。
{"title":"R and D Cloud CEIB: Management and Knowledge Extraction System for Bioimaging in the Cloud","authors":"J. M. S. Serrano, M. A. C. Quevedo, M. de la Iglesia-Vaya, L. Martí-Bonmatí, R. Valenzuela","doi":"10.1109/ICBEB.2012.323","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.323","url":null,"abstract":"The management and knowledge extraction system for bioimaging in the cloud (R & D Cloud CEIB) which is proposed in this article will use the services offered by the centralization of bioimaging through Valencian Biobank Medical Imaging (GIMC) as a basis for managing and extracting knowledge from a bioimaging bank, providing that knowledge in the form of services with high added value and expertise to the Electronic Patient History System (HSE), thus bringing the results of R & D to the patient, improving the quality of the information contained therein. R & D Cloud CEIB has four general modules: Search engine (SE), manager of clinical trials (GEBID), anonymizer (ANON) and bioimage knowledge engine (BIKE). The BIKE is the central module and through its sub modules analyzes and generates knowledge to provide to the HSE through services. The technology used in R & D Cloud CEIB is completely based on Open Source. Within the BIKE, we focus on the development of the classifier module (BIKE-Classifier), which aims to establish a method for the extraction of biomarkers for bioimaging and subsequent analysis to obtain a classification in bioimaging available pools following GIMC diagnostic experiences.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"1 1","pages":"469-472"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89191013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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