Journal of hazardous materials advances最新文献_第10页

The bioplastic paradox: Biodegradable microplastics trigger species-specific nitro-oxidative stress and root growth inhibition in Brassicaceae 生物塑料悖论：可生物降解的微塑料引发了十字花科物种特异性的氮氧化应激和根生长抑制

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100936

Enikő Mészáros , Alice Gere , Kamilla Kovács , Zsófia Liska , Klaudia Hoffmann , Attila Bodor , Gábor Feigl

Biodegradable plastics are increasingly being used in agriculture as alternatives to conventional polymers, yet their environmental safety remains poorly understood. Although marketed as environmentally friendly, many degrade incompletely and persist as microplastics, raising concerns about their biological effects. Here we assess how two biodegradable microplastic formulations influence early root development and nitro-oxidative stress in two Brassicaceae species, oilseed rape (Brassica napus) and garden cress (Lepidium sativum), under in vitro exposure at 0.5% and 1% (w/v). Oilseed rape maintained root growth and redox balance through coordinated activation of antioxidant enzymes and non-enzymatic defenses, with limited protein nitration. In contrast, garden cress exhibited strong growth inhibition, elevated reactive oxygen and nitrogen species, extensive protein nitration, and suppressed antioxidant responses. Increased metabolic activity under high-dose exposure was consistent with stress-related metabolic adjustment rather than recovery. These results reveal that biodegradable microplastics can induce species- and polymer-specific nitro-oxidative stress even at realistic exposure levels. The findings highlight nitrosative biomarkers as sensitive indicators of sub-lethal phytotoxicity and provide a mechanistic basis for improving ecological risk assessments of biodegradable plastics in agriculture.

Environmental implications

Biodegradable plastics are promoted as sustainable alternatives to conventional polymers, but their environmental safety is often assumed rather than demonstrated. This study shows that even short-term exposure to biodegradable microplastics can induce species- and polymer-specific nitro-oxidative stress in plants. Sensitive species such as garden cress exhibit clear biochemical and metabolic disruption, highlighting the need for caution in the adoption of such materials in agriculture. These findings underscore the importance of including nitro-oxidative biomarkers and species sensitivity screening in future risk assessments and regulatory frameworks addressing biodegradable plastic use in soil-based environments.

可生物降解塑料作为传统聚合物的替代品越来越多地用于农业，但其环境安全性仍然知之甚少。尽管在市场上宣传环保，但许多塑料不能完全降解，并以微塑料的形式存在，这引起了人们对其生物效应的担忧。本研究评估了两种可生物降解的微塑料配方在0.5%和1% （w/v）的体外暴露条件下对两种芸苔科植物油菜（Brassica napus）和芥蓝（Lepidium sativum）早期根系发育和氮氧化胁迫的影响。油菜通过协调激活抗氧化酶和非酶防御来维持根系生长和氧化还原平衡，限制蛋白质硝化。相比之下，园菜表现出强烈的生长抑制，活性氧和氮含量升高，蛋白质硝化广泛，抗氧化反应受到抑制。高剂量暴露下代谢活动的增加与应激相关的代谢调节一致，而不是恢复。这些结果表明，即使在实际暴露水平下，可生物降解的微塑料也可以诱导物种和聚合物特异性的硝基氧化应激。研究结果强调了亚硝化生物标志物是亚致死植物毒性的敏感指标，并为改进农业生物降解塑料的生态风险评估提供了机制基础。环境影响可生物降解塑料被认为是传统聚合物的可持续替代品，但其环境安全性往往是假设的，而不是证明的。这项研究表明，即使短期暴露于可生物降解的微塑料也能诱导植物产生物种特异性和聚合物特异性的氮氧化应激。一些敏感的物种，如园菜，表现出明显的生化和代谢破坏，强调在农业中采用这类材料时需要谨慎。这些发现强调了在未来的风险评估和监管框架中纳入硝基氧化生物标志物和物种敏感性筛选的重要性，以解决在土壤环境中使用可生物降解塑料的问题。

{"title":"The bioplastic paradox: Biodegradable microplastics trigger species-specific nitro-oxidative stress and root growth inhibition in Brassicaceae","authors":"Enikő Mészáros , Alice Gere , Kamilla Kovács , Zsófia Liska , Klaudia Hoffmann , Attila Bodor , Gábor Feigl","doi":"10.1016/j.hazadv.2025.100936","DOIUrl":"10.1016/j.hazadv.2025.100936","url":null,"abstract":"<div><div>Biodegradable plastics are increasingly being used in agriculture as alternatives to conventional polymers, yet their environmental safety remains poorly understood. Although marketed as environmentally friendly, many degrade incompletely and persist as microplastics, raising concerns about their biological effects. Here we assess how two biodegradable microplastic formulations influence early root development and nitro-oxidative stress in two Brassicaceae species, oilseed rape (<em>Brassica napus</em>) and garden cress (<em>Lepidium sativum</em>), under <em>in vitro</em> exposure at 0.5% and 1% (w/v). Oilseed rape maintained root growth and redox balance through coordinated activation of antioxidant enzymes and non-enzymatic defenses, with limited protein nitration. In contrast, garden cress exhibited strong growth inhibition, elevated reactive oxygen and nitrogen species, extensive protein nitration, and suppressed antioxidant responses. Increased metabolic activity under high-dose exposure was consistent with stress-related metabolic adjustment rather than recovery. These results reveal that biodegradable microplastics can induce species- and polymer-specific nitro-oxidative stress even at realistic exposure levels. The findings highlight nitrosative biomarkers as sensitive indicators of sub-lethal phytotoxicity and provide a mechanistic basis for improving ecological risk assessments of biodegradable plastics in agriculture.</div></div><div><h3>Environmental implications</h3><div>Biodegradable plastics are promoted as sustainable alternatives to conventional polymers, but their environmental safety is often assumed rather than demonstrated. This study shows that even short-term exposure to biodegradable microplastics can induce species- and polymer-specific nitro-oxidative stress in plants. Sensitive species such as garden cress exhibit clear biochemical and metabolic disruption, highlighting the need for caution in the adoption of such materials in agriculture. These findings underscore the importance of including nitro-oxidative biomarkers and species sensitivity screening in future risk assessments and regulatory frameworks addressing biodegradable plastic use in soil-based environments.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100936"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Slag carbonation-driven surface activation for simultaneous crystallization of heavy metals: Implications for carbon mineralization and environmental remediation 矿渣碳化驱动的重金属同步结晶表面活化：碳矿化和环境修复的意义

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100921

Yuqing Liu , Tingting Li , Bin Liu , Jie Xu , Hang Zhai

Carbon dioxide (CO₂) mineralization via enhanced aqueous carbonation of alkaline industrial residues, such as slags, offers dual benefits of carbon sequestration and solid waste utilization. However, a substantial portion of the resulting carbonated materials remains underutilized. In this study, we investigated the potential of alkali-activated slags for improved aqueous carbonation and assessed the capacity of the resulting carbonated products to immobilize heavy metals (HMs), specifically Cd (Ⅱ), Pb (Ⅱ), and Cu (Ⅱ), from aqueous environments. Systematic batch experiments were conducted to evaluate HMs removal efficiencies under varying NaOH pretreatment concentrations (0–4 M), reaction times (0–720 min), initial HMs concentrations (0–1000 ppm), pH levels (4–7), and ionic strengths ([NaCl] from 0 to 10⁴ ppm). The results revealed a consistent removal efficiency ranking: carbonated slags > alkali-activated slags > raw slags. Leaching tests further confirmed that carbonated slags exhibited enhanced HMs retention, with greater resistance to acid dissolution and ionic interference. These findings highlight the potential of enhanced aqueous slag carbonation not only for carbon capture and storage but also for HMs remediation, offering an integrated approach to negative emissions and environmental pollution control.

通过增强碱性工业残留物（如炉渣）的水碳化作用，二氧化碳（CO 2）矿化具有固碳和固体废物利用的双重效益。然而，所产生的碳酸材料的很大一部分仍未得到充分利用。在这项研究中，我们研究了碱活化渣改善水碳酸化的潜力，并评估了所得碳酸化产物固定水环境中重金属（hm）的能力，特别是Cd（Ⅱ）、Pb（Ⅱ）和Cu（Ⅱ）。通过系统的批量实验来评估不同NaOH预处理浓度（0 - 4 M）、反应时间（0 - 720 min）、初始HMs浓度（0 - 1000 ppm）、pH值（4-7）和离子强度（[NaCl] 0 - 104 ppm）下HMs的去除效率。结果显示了一致的去除效率排序：碳化渣+碱活性渣+生渣。浸出试验进一步证实，碳化渣表现出增强的HMs保留率，具有更强的抗酸溶和离子干扰能力。这些发现强调了强化水渣碳化不仅在碳捕获和储存方面有潜力，而且在HMs修复方面也有潜力，为负排放和环境污染控制提供了一种综合方法。

{"title":"Slag carbonation-driven surface activation for simultaneous crystallization of heavy metals: Implications for carbon mineralization and environmental remediation","authors":"Yuqing Liu , Tingting Li , Bin Liu , Jie Xu , Hang Zhai","doi":"10.1016/j.hazadv.2025.100921","DOIUrl":"10.1016/j.hazadv.2025.100921","url":null,"abstract":"<div><div>Carbon dioxide (CO₂) mineralization via enhanced aqueous carbonation of alkaline industrial residues, such as slags, offers dual benefits of carbon sequestration and solid waste utilization. However, a substantial portion of the resulting carbonated materials remains underutilized. In this study, we investigated the potential of alkali-activated slags for improved aqueous carbonation and assessed the capacity of the resulting carbonated products to immobilize heavy metals (HMs), specifically Cd (Ⅱ), Pb (Ⅱ), and Cu (Ⅱ), from aqueous environments. Systematic batch experiments were conducted to evaluate HMs removal efficiencies under varying NaOH pretreatment concentrations (0–4 M), reaction times (0–720 min), initial HMs concentrations (0–1000 ppm), pH levels (4–7), and ionic strengths ([NaCl] from 0 to 10<sup>4</sup> ppm). The results revealed a consistent removal efficiency ranking: carbonated slags > alkali-activated slags > raw slags. Leaching tests further confirmed that carbonated slags exhibited enhanced HMs retention, with greater resistance to acid dissolution and ionic interference. These findings highlight the potential of enhanced aqueous slag carbonation not only for carbon capture and storage but also for HMs remediation, offering an integrated approach to negative emissions and environmental pollution control.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100921"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145416486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Twenty exposure concentrations, zero dose-response for subcellular biomarkers: Unravelling this paradox in cadmium and copper exposed Dreissena polymorpha 20个暴露浓度，亚细胞生物标志物的零剂量反应：揭示镉和铜暴露的多形菜中的这一悖论

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100922

Manon Bain , Simon Devin , Marie Zaffino , Sandrine Pain-Devin

The assessment of aquatic ecosystem quality under the Water Framework Directive suffers from a gap between chemical measurements and observed effects at the community level, with a critical lack of direct measurements of organism health. Biomarkers, situated at intermediate levels, could bridge this gap but cause-effect relationships remain poorly understood, limiting their operationality. This study implements an innovative experimental protocol with 20 exposure concentrations in order to answer 4 questions: (i) Is there a dose-response relationship for both subcellular biomarkers and tissue concentrations? (ii) Does exposure duration influence the response of biomarkers? (iii) Does response pattern of biomarkers differ between cadmium and copper? The results obtained and used to answer the first three questions gave rise to another one: (iv) How did the inter-individual variability and statistical power of our experimental design influence our ability to detect biological effects? Dreissena polymorpha was exposed to cadmium and copper for 4 and 8 days, with measurement of 8 biomarkers (SOD, GPx, TAC, GST, CSP3, LOOH, ETS, LDH) and tissue metal concentrations. Results reveal a paradox: while dose-response relationships were confirmed for bioaccumulation and mortality, subcellular biomarkers showed no dose-response relationships. Exposure duration had no influence, but correlation networks revealed different biomarker response patterns between cadmium and copper. Prospective analysis demonstrated that a sample size of 6–-10 individuals per group would optimise statistical detection. This study reports on the difficulties associated with applying biomarkers under controlled conditions, provides data on the model species Dreissena polymorpha and contributes to the debate on the operationality of biomarkers.

根据《水框架指令》对水生生态系统质量进行的评估存在着化学测量与在社区一级观察到的影响之间的差距，严重缺乏对生物体健康的直接测量。位于中间水平的生物标志物可以弥补这一差距，但对因果关系的了解仍然很少，限制了它们的可操作性。本研究采用了一种创新的实验方案，包含20种暴露浓度，以回答4个问题：(i)亚细胞生物标志物和组织浓度是否存在剂量-反应关系？（ii）暴露时间是否会影响生物标志物的反应？（iii）镉和铜对生物标志物的反应模式是否不同？获得并用于回答前三个问题的结果引出了另一个问题：（iv）我们的实验设计的个体间变异性和统计能力如何影响我们检测生物效应的能力？将多形蛇暴露于镉和铜中4和8天，测量8种生物标志物（SOD、GPx、TAC、GST、CSP3、LOOH、ETS、LDH）和组织金属浓度。结果揭示了一个悖论：虽然生物积累和死亡率证实了剂量-反应关系，但亚细胞生物标志物没有显示剂量-反应关系。暴露时间没有影响，但相关网络揭示了镉和铜之间不同的生物标志物响应模式。前瞻性分析表明，每组6 -10个人的样本量将优化统计检测。本研究报告了在受控条件下应用生物标志物的困难，提供了模式物种多形菜的数据，并对生物标志物的可操作性进行了讨论。

{"title":"Twenty exposure concentrations, zero dose-response for subcellular biomarkers: Unravelling this paradox in cadmium and copper exposed Dreissena polymorpha","authors":"Manon Bain , Simon Devin , Marie Zaffino , Sandrine Pain-Devin","doi":"10.1016/j.hazadv.2025.100922","DOIUrl":"10.1016/j.hazadv.2025.100922","url":null,"abstract":"<div><div>The assessment of aquatic ecosystem quality under the Water Framework Directive suffers from a gap between chemical measurements and observed effects at the community level, with a critical lack of direct measurements of organism health. Biomarkers, situated at intermediate levels, could bridge this gap but cause-effect relationships remain poorly understood, limiting their operationality. This study implements an innovative experimental protocol with 20 exposure concentrations in order to answer 4 questions: (i) Is there a dose-response relationship for both subcellular biomarkers and tissue concentrations? (ii) Does exposure duration influence the response of biomarkers? (iii) Does response pattern of biomarkers differ between cadmium and copper? The results obtained and used to answer the first three questions gave rise to another one: (iv) How did the inter-individual variability and statistical power of our experimental design influence our ability to detect biological effects? <em>Dreissena polymorpha</em> was exposed to cadmium and copper for 4 and 8 days, with measurement of 8 biomarkers (SOD, GPx, TAC, GST, CSP3, LOOH, ETS, LDH) and tissue metal concentrations. Results reveal a paradox: while dose-response relationships were confirmed for bioaccumulation and mortality, subcellular biomarkers showed no dose-response relationships. Exposure duration had no influence, but correlation networks revealed different biomarker response patterns between cadmium and copper. Prospective analysis demonstrated that a sample size of 6–-10 individuals per group would optimise statistical detection. This study reports on the difficulties associated with applying biomarkers under controlled conditions, provides data on the model species <em>Dreissena polymorpha</em> and contributes to the debate on the operationality of biomarkers.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100922"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145416488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Probabilistic health risk assessment of heavy metals in vegetables cultivated near tin mining sites in Jos Plateau State, Nigeria 尼日利亚乔斯高原州锡矿附近种植的蔬菜中重金属的健康风险概率评估

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100934

Timothy Titus Falae , Chika Pearl Ossai , Muyiwa Michael Orosun , Prosper Manu Abdulai , Godswill J. Udom , John Kanayochukwu Nduka , Chideraa Courage Offor , Orish Ebere Orisakwe

This study conducted a comprehensive probabilistic health risk assessment of heavy metals in vegetables cultivated near tin mining sites in Jos Plateau State, Nigeria. Samples of tomatoes, cabbage, and carrots were collected from the Kwata area and around the University of Jos and analyzed for arsenic (As), antimony (Sb), cadmium (Cd), lead (Pb), and tin (Sn). Results revealed elevated concentrations of all metals, with As and Sb frequently exceeding WHO permissible limits of 0.01 mg/kg and 0.02 mg/kg, respectively. Cabbage from University of Jos recorded the highest levels, with As (0.06 ± 0.010 mg/kg) and Pb (0.07 ± 0.013 mg/kg). Deterministic estimates of Estimated Daily Intake (EDI), Target Hazard Quotient (THQ), and Hazard Index (HI) showed significant non-carcinogenic risks, particularly among children, with THQ values for As ranging from 2.4 to 2.9 and HI peaking at 4.6 in cabbage. To enhance risk characterization, Monte Carlo Simulation (10,000 iterations) was applied to estimate Lifetime Carcinogenic Risk (LCR) under uncertainty. As emerged as the dominant contributor to cancer risk, accounting for approximately 96 % of the total burden. Children exhibited the highest Total LCR values, ranging from 1.2 × 10⁻³ to 1.5 × 10⁻³, more than tenfold above the USEPA’s acceptable threshold of 1.0 × 10⁻⁴. These findings highlight a significant environmental health challenge linked to vegetable consumption in mining-impacted areas. Immediate public health interventions, environmental remediation, and sustained monitoring are urgently recommended to mitigate long-term exposure, especially in vulnerable populations.

本研究对尼日利亚乔斯高原州锡矿场附近种植的蔬菜中的重金属进行了全面的健康风险概率评估。从Kwata地区和乔斯大学周围收集了西红柿、卷心菜和胡萝卜的样本，并分析了砷（As）、锑（Sb）、镉（Cd）、铅（Pb）和锡（Sn）。结果显示，所有金属的浓度都有所升高，砷和锑分别超过世界卫生组织允许的0.01 mg/kg和0.02 mg/kg。美国乔斯大学产的白菜中砷（0.06±0.010 mg/kg）和铅（0.07±0.013 mg/kg）含量最高。对估计每日摄入量（EDI）、目标危害商（THQ）和危害指数（HI）的确定性估计显示出显著的非致癌风险，特别是在儿童中，白菜中As的THQ值在2.4至2.9之间，HI值在4.6达到峰值。为了加强风险表征，应用蒙特卡罗模拟（10,000次迭代）来估计不确定情况下的终生致癌风险（LCR）。它成为癌症风险的主要因素，约占总负担的96%。儿童表现出最高的总LCR值，从1.2 × 10⁻³到1.5 × 10⁻³，比美国环境保护局可接受的1.0 × 10毒血症阈值高出十倍以上。这些发现突出了受采矿影响地区与蔬菜消费有关的重大环境健康挑战。紧急建议立即采取公共卫生干预措施、环境补救和持续监测，以减轻长期接触，特别是在脆弱人群中。

{"title":"Probabilistic health risk assessment of heavy metals in vegetables cultivated near tin mining sites in Jos Plateau State, Nigeria","authors":"Timothy Titus Falae , Chika Pearl Ossai , Muyiwa Michael Orosun , Prosper Manu Abdulai , Godswill J. Udom , John Kanayochukwu Nduka , Chideraa Courage Offor , Orish Ebere Orisakwe","doi":"10.1016/j.hazadv.2025.100934","DOIUrl":"10.1016/j.hazadv.2025.100934","url":null,"abstract":"<div><div>This study conducted a comprehensive probabilistic health risk assessment of heavy metals in vegetables cultivated near tin mining sites in Jos Plateau State, Nigeria. Samples of tomatoes, cabbage, and carrots were collected from the Kwata area and around the University of Jos and analyzed for arsenic (As), antimony (Sb), cadmium (Cd), lead (Pb), and tin (Sn). Results revealed elevated concentrations of all metals, with As and Sb frequently exceeding WHO permissible limits of 0.01 mg/kg and 0.02 mg/kg, respectively. Cabbage from University of Jos recorded the highest levels, with As (0.06 ± 0.010 mg/kg) and Pb (0.07 ± 0.013 mg/kg). Deterministic estimates of Estimated Daily Intake (EDI), Target Hazard Quotient (THQ), and Hazard Index (HI) showed significant non-carcinogenic risks, particularly among children, with THQ values for As ranging from 2.4 to 2.9 and HI peaking at 4.6 in cabbage. To enhance risk characterization, Monte Carlo Simulation (10,000 iterations) was applied to estimate Lifetime Carcinogenic Risk (LCR) under uncertainty. As emerged as the dominant contributor to cancer risk, accounting for approximately 96 % of the total burden. Children exhibited the highest Total LCR values, ranging from 1.2 <strong>×</strong> 10⁻³ to 1.5 <strong>×</strong> 10⁻³, more than tenfold above the USEPA’s acceptable threshold of 1.0 <strong>×</strong> 10⁻<sup>4</sup>. These findings highlight a significant environmental health challenge linked to vegetable consumption in mining-impacted areas. Immediate public health interventions, environmental remediation, and sustained monitoring are urgently recommended to mitigate long-term exposure, especially in vulnerable populations.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100934"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The promising role of purple phototrophic bacteria in achieving the United Nations Sustainable Development Goals 紫色光养细菌在实现联合国可持续发展目标中的重要作用

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100884

Ali Amini, Valiallah Amirian Mojarad, Simone Rossi, Andrea Turolla

Purple phototrophic bacteria (PPB) offer a versatile and sustainable solution for addressing several of the United Nations Sustainable Development Goals (SDGs). These goals underscore essential objectives that must be addressed to face different environmental and societal challenges and foster sustainable and circular innovative biotechnologies. PPB are recognized for their multiple valuable applications, contributing to wastewater treatment, nutrient recovery, and the production of biopolymers, single-cell protein, biofertilizers, biohydrogen, and other value-added products. This work discusses the significant roles of PPB in achieving various SDGs, highlighting their direct contributions to SDG 1 (no poverty), SDG 2 (zero hunger), SDG 3 (good health and well-being), SDG 6 (clean water and sanitation), SDG 7 (affordable and clean energy), SDG 12 (responsible consumption and production), SDG 13 (climate action), SDG 14 (life below water), and SDG 15 (life on land). Additionally, the critical barriers to scaling up and commercializing PPB-based biotechnologies are discussed. Addressing these barriers, along with market development and supportive policies, will be essential to accelerating the transition to sustainable development.

紫色光养细菌（PPB）为实现联合国可持续发展目标（sdg）提供了一种多功能和可持续的解决方案。这些目标强调了必须解决的基本目标，以面对不同的环境和社会挑战，并促进可持续和循环的创新生物技术。PPB因其多种有价值的应用而得到认可，有助于废水处理，养分回收，生物聚合物，单细胞蛋白，生物肥料，生物氢和其他增值产品的生产。本工作讨论了PPB在实现各种可持续发展目标方面的重要作用，强调了它们对可持续发展目标1（无贫困）、可持续发展目标2（零饥饿）、可持续发展目标3（良好健康和福祉）、可持续发展目标6（清洁水和卫生设施）、可持续发展目标7（负担得起的清洁能源）、可持续发展目标12（负责任的消费和生产）、可持续发展目标13（气候行动）、可持续发展目标14（水下生命）和可持续发展目标15（陆地生命）的直接贡献。此外，讨论了扩大和商业化基于ppb的生物技术的关键障碍。消除这些障碍，再加上市场发展和支持性政策，对于加速向可持续发展过渡至关重要。

{"title":"The promising role of purple phototrophic bacteria in achieving the United Nations Sustainable Development Goals","authors":"Ali Amini, Valiallah Amirian Mojarad, Simone Rossi, Andrea Turolla","doi":"10.1016/j.hazadv.2025.100884","DOIUrl":"10.1016/j.hazadv.2025.100884","url":null,"abstract":"<div><div>Purple phototrophic bacteria (PPB) offer a versatile and sustainable solution for addressing several of the United Nations Sustainable Development Goals (SDGs). These goals underscore essential objectives that must be addressed to face different environmental and societal challenges and foster sustainable and circular innovative biotechnologies. PPB are recognized for their multiple valuable applications, contributing to wastewater treatment, nutrient recovery, and the production of biopolymers, single-cell protein, biofertilizers, biohydrogen, and other value-added products. This work discusses the significant roles of PPB in achieving various SDGs, highlighting their direct contributions to SDG 1 (no poverty), SDG 2 (zero hunger), SDG 3 (good health and well-being), SDG 6 (clean water and sanitation), SDG 7 (affordable and clean energy), SDG 12 (responsible consumption and production), SDG 13 (climate action), SDG 14 (life below water), and SDG 15 (life on land). Additionally, the critical barriers to scaling up and commercializing PPB-based biotechnologies are discussed. Addressing these barriers, along with market development and supportive policies, will be essential to accelerating the transition to sustainable development.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100884"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microplastics in agricultural soils: Evidence from an industrial suburb of Bangladesh 农业土壤中的微塑料：来自孟加拉国工业郊区的证据

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100928

Md Ashraful Islam , Md Bayazid Hossain , Mohammad Enayet Hossain , Md Yousuf Gazi , Badhan Saha , Md Mahin Uddin

‘Microplastics’ (MPs) are increasingly recognized as emerging soil contaminants, yet their vertical distribution in agricultural systems−particularly in developing regions−remains poorly documented. This study examined MP abundance and characteristics in agricultural soils of central Bangladesh, a rapidly urbanizing agro-industrial zone. Soil samples were collected from 20 agricultural fields adjacent to homesteads, roadways, industries, landfills, and mulches at two depths (0−15 and 15−30 cm). Microplastics were extracted using density separation and wet digestion, identified by stereomicroscopy, and confirmed via ATR-FTIR spectroscopy. Results revealed the widespread presence of microplastics across all sites, with surface soils ranging from 540 to 1926 items/kg and subsurface soils from 253 to 1286 items/kg. Fibers, blue-colored particles, and particles smaller than 1 mm dominated the samples, while common polymer types included polyethylene (PE) and polypropylene (PP). Risk indices indicated moderate to substantial ecological concern, with pollution load values varying by proximity to local sources. As one of the first regional assessments of subsurface MPs in agricultural soils in South Asia, this study establishes critical baseline evidence for terrestrial microplastic transport. These findings highlight agricultural soils as a significant sink of microplastics in Bangladesh and underscore the need for management strategies to mitigate their potential impacts on food security and environmental health.

“微塑料”（MPs）越来越被认为是一种新兴的土壤污染物，但它们在农业系统中的垂直分布——特别是在发展中地区——仍然缺乏文献记录。本研究考察了孟加拉国中部农业土壤中MP的丰度和特征，这是一个快速城市化的农业工业区。土壤样本采集于20个农田、道路、工业、垃圾填埋场和地膜附近，深度分别为0 - 15 cm和15 - 30 cm。微塑料采用密度分离和湿消化提取，体视显微镜鉴定，ATR-FTIR光谱鉴定。结果显示，微塑料在所有地点广泛存在，表层土壤为540至1926项/kg，地下土壤为253至1286项/kg。这些样品主要是纤维、蓝色颗粒和小于1毫米的颗粒，而常见的聚合物类型包括聚乙烯（PE）和聚丙烯（PP）。风险指数显示中度至严重的生态问题，污染负荷值因靠近当地污染源而异。作为南亚农业土壤中地下微塑料的首批区域评估之一，本研究为陆地微塑料运输建立了关键的基线证据。这些发现强调了农业土壤是孟加拉国微塑料的一个重要汇，并强调需要制定管理战略，以减轻其对粮食安全和环境健康的潜在影响。

{"title":"Microplastics in agricultural soils: Evidence from an industrial suburb of Bangladesh","authors":"Md Ashraful Islam , Md Bayazid Hossain , Mohammad Enayet Hossain , Md Yousuf Gazi , Badhan Saha , Md Mahin Uddin","doi":"10.1016/j.hazadv.2025.100928","DOIUrl":"10.1016/j.hazadv.2025.100928","url":null,"abstract":"<div><div>‘Microplastics’ (MPs) are increasingly recognized as emerging soil contaminants, yet their vertical distribution in agricultural systems−particularly in developing regions−remains poorly documented. This study examined MP abundance and characteristics in agricultural soils of central Bangladesh, a rapidly urbanizing agro-industrial zone. Soil samples were collected from 20 agricultural fields adjacent to homesteads, roadways, industries, landfills, and mulches at two depths (0−15 and 15−30 cm). Microplastics were extracted using density separation and wet digestion, identified by stereomicroscopy, and confirmed via ATR-FTIR spectroscopy. Results revealed the widespread presence of microplastics across all sites, with surface soils ranging from 540 to 1926 items/kg and subsurface soils from 253 to 1286 items/kg. Fibers, blue-colored particles, and particles smaller than 1 mm dominated the samples, while common polymer types included polyethylene (PE) and polypropylene (PP). Risk indices indicated moderate to substantial ecological concern, with pollution load values varying by proximity to local sources. As one of the first regional assessments of subsurface MPs in agricultural soils in South Asia, this study establishes critical baseline evidence for terrestrial microplastic transport. These findings highlight agricultural soils as a significant sink of microplastics in Bangladesh and underscore the need for management strategies to mitigate their potential impacts on food security and environmental health.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100928"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PFAS and heavy metals mixture in vitro: Insights into synergistic toxicity across multiple cell lines PFAS和重金属混合物在体外：对多种细胞系的协同毒性的见解

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100913

Mia Sands , Arshveer Sachdeva , Laura Bukavina , Joseph Irudayaraj

Poly- and perfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants originating from industrial processes. While the individual toxicities of PFAS and heavy metals have been extensively studied, their co-occurrence in the environment raises concerns on potential interactions that may amplify their effects on human health. Specifically, the manner in which heavy metals influence PFAS absorption, bioavailability, and combined toxicity remain poorly understood. This knowledge gap limits our ability to assess the true health risks associated with real-world co-exposures to these contaminants. To address this gap, our study investigates the mixture effects of PFAS and heavy metals on human cell viability, proliferation, migration, and DNA damage across five human cell lines (HepG2, A498, A549, A431, and PC3) at human-relevant exposure levels. In our study, 1 µM PFOA and GenX, along with 0.01 µM lead and arsenic, were chosen to represent human exposure levels. Our results revealed cell-type-specific responses, with mostly synergistic interactions observed across different cell lines. HepG2 and A549 cells exhibited impaired cell proliferation, increased DNA damage, and reduced cell migration upon mixture exposure, while A498 and PC3 cells showed increased cell proliferation, with less pronounced effects on DNA damage and migration. These findings suggest that PFAS and heavy metal mixtures can impact cellular functions through cell-type and combination-specific toxicological pathways. This study provides new insights into the complex interactions between PFAS and heavy metals, highlighting the need for further research to better understand the underlying mechanisms and its impact on health risks associated with co-exposure to these environmental contaminants.

聚氟烷基和全氟烷基物质（PFAS）是普遍存在的来自工业过程的环境污染物。虽然对全氟磺酸钠和重金属的个体毒性进行了广泛的研究，但它们在环境中的共存引起了人们对潜在相互作用的关注，这种相互作用可能会放大它们对人类健康的影响。具体来说，重金属影响PFAS吸收、生物利用度和综合毒性的方式仍然知之甚少。这种知识差距限制了我们评估与现实世界中共同接触这些污染物相关的真正健康风险的能力。为了解决这一空白，本研究调查了PFAS和重金属在人类相关暴露水平下对五种人类细胞系（HepG2、A498、A549、A431和PC3）的人类细胞活力、增殖、迁移和DNA损伤的混合影响。在我们的研究中，选择1µM的PFOA和GenX，以及0.01µM的铅和砷来代表人体暴露水平。我们的结果揭示了细胞类型特异性反应，主要是在不同细胞系中观察到的协同相互作用。混合暴露后，HepG2和A549细胞增殖受损，DNA损伤增加，细胞迁移减少，而A498和PC3细胞增殖增加，DNA损伤和迁移影响不明显。这些发现表明，PFAS和重金属混合物可以通过细胞类型和组合特异性毒理学途径影响细胞功能。这项研究为PFAS与重金属之间复杂的相互作用提供了新的见解，强调了进一步研究的必要性，以更好地了解潜在机制及其对与这些环境污染物共同暴露相关的健康风险的影响。

{"title":"PFAS and heavy metals mixture in vitro: Insights into synergistic toxicity across multiple cell lines","authors":"Mia Sands , Arshveer Sachdeva , Laura Bukavina , Joseph Irudayaraj","doi":"10.1016/j.hazadv.2025.100913","DOIUrl":"10.1016/j.hazadv.2025.100913","url":null,"abstract":"<div><div>Poly- and perfluoroalkyl substances (PFAS) are ubiquitous environmental contaminants originating from industrial processes. While the individual toxicities of PFAS and heavy metals have been extensively studied, their co-occurrence in the environment raises concerns on potential interactions that may amplify their effects on human health. Specifically, the manner in which heavy metals influence PFAS absorption, bioavailability, and combined toxicity remain poorly understood. This knowledge gap limits our ability to assess the true health risks associated with real-world co-exposures to these contaminants. To address this gap, our study investigates the mixture effects of PFAS and heavy metals on human cell viability, proliferation, migration, and DNA damage across five human cell lines (HepG2, A498, A549, A431, and PC3) at human-relevant exposure levels. In our study, 1 µM PFOA and GenX, along with 0.01 µM lead and arsenic, were chosen to represent human exposure levels. Our results revealed cell-type-specific responses, with mostly synergistic interactions observed across different cell lines. HepG2 and A549 cells exhibited impaired cell proliferation, increased DNA damage, and reduced cell migration upon mixture exposure, while A498 and PC3 cells showed increased cell proliferation, with less pronounced effects on DNA damage and migration. These findings suggest that PFAS and heavy metal mixtures can impact cellular functions through cell-type and combination-specific toxicological pathways. This study provides new insights into the complex interactions between PFAS and heavy metals, highlighting the need for further research to better understand the underlying mechanisms and its impact on health risks associated with co-exposure to these environmental contaminants.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100913"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous determination of eight tetracyclines in cattle hair using UPLC-QTRAP/MS: A novel non-invasive strategy for veterinary drug residue UPLC-QTRAP/MS同时测定牛毛中8种四环素类药物：一种新的兽药残留无创检测策略

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100939

Zhanteng Song , Zhixin An , Maerhaba Paerhati , Adilitai Tielik , Jinrong Zhu , Gayna Serhali , Decheng Suo

The environmental residues caused by the abuse of tetracycline antibiotics (TCS) in animal husbandry threaten ecology and human health through the food chain, but the traditional biological matrix (such as blood and urine) is difficult to achieve long-term drug monitoring due to its strong invasiveness and short metabolic cycle. In this study, a high sensitivity method based on UPLC-Qtrap/MS was established, using bovine hair as a non-invasive detection matrix, which can simultaneously detect eight tetracycline antibiotics. The method validation showed that the linear correlation coefficient was>0.999, the recovery was 82.79 – 98.55 %, the coefficient of variation was<15 %, the limit of detection (LOD) and limit of quantification (LOQ) were 0.3 ng/kg and 1.0 ng/kg, respectively, which was significantly better than the existing methods. The method was successfully applied to a pilot study of 50 cattle hair samples from the northern region of Xinjiang, China, demonstrating its practical applicability. The microstructure, chemical composition and possible metabolic pathways into the hair after treatment with tetracycline were briefly investigated.The result and research shows that cattle hair can stably enrich drug residues for a long time, which provides an innovative solution for tracing illegal drug use in animal husbandry, and provides technical support for the formulation of new drug regulatory standards and environmental health risk assessment.

畜牧业滥用四环素类抗生素（TCS）造成的环境残留物通过食物链威胁生态和人类健康，但传统的生物基质（如血液和尿液）因其侵入性强、代谢周期短，难以实现长期的药物监测。本研究以牛毛为无创检测基质，建立了一种基于UPLC-Qtrap/MS的高灵敏度检测方法，可同时检测8种四环素类抗生素。方法验证表明，线性相关系数为0.999，回收率为82.79 ~ 98.55%，变异系数为15%，检出限（LOD）和定量限（LOQ）分别为0.3 ng/kg和1.0 ng/kg，显著优于现有方法。该方法已成功应用于中国新疆北部地区50份牛毛样品的中试研究，证明了该方法的实用性。简要研究了四环素处理后毛发的微观结构、化学成分和可能的代谢途径。结果与研究表明，牛毛可长期稳定富集药物残留，为畜牧业非法用药溯源提供创新解决方案，为新药监管标准制定和环境健康风险评估提供技术支撑。

{"title":"Simultaneous determination of eight tetracyclines in cattle hair using UPLC-QTRAP/MS: A novel non-invasive strategy for veterinary drug residue","authors":"Zhanteng Song , Zhixin An , Maerhaba Paerhati , Adilitai Tielik , Jinrong Zhu , Gayna Serhali , Decheng Suo","doi":"10.1016/j.hazadv.2025.100939","DOIUrl":"10.1016/j.hazadv.2025.100939","url":null,"abstract":"<div><div>The environmental residues caused by the abuse of tetracycline antibiotics (TCS) in animal husbandry threaten ecology and human health through the food chain, but the traditional biological matrix (such as blood and urine) is difficult to achieve long-term drug monitoring due to its strong invasiveness and short metabolic cycle. In this study, a high sensitivity method based on UPLC-Qtrap/MS was established, using bovine hair as a non-invasive detection matrix, which can simultaneously detect eight tetracycline antibiotics. The method validation showed that the linear correlation coefficient was>0.999, the recovery was 82.79 – 98.55 %, the coefficient of variation was<15 %, the limit of detection (LOD) and limit of quantification (LOQ) were 0.3 ng/kg and 1.0 ng/kg, respectively, which was significantly better than the existing methods. The method was successfully applied to a pilot study of 50 cattle hair samples from the northern region of Xinjiang, China, demonstrating its practical applicability. The microstructure, chemical composition and possible metabolic pathways into the hair after treatment with tetracycline were briefly investigated.The result and research shows that cattle hair can stably enrich drug residues for a long time, which provides an innovative solution for tracing illegal drug use in animal husbandry, and provides technical support for the formulation of new drug regulatory standards and environmental health risk assessment.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100939"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A global evaluation of exposure to pollutants in 3D printing: A systematic review and meta-analysis 3D打印中污染物暴露的全球评估：系统回顾和荟萃分析

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100931

Amir Hossein Khoshakhlagh , Saleh Al Sulaie , Saeid Yazdanirad , Agnieszka Gruszecka-Kosowska

Concerns persist regarding potential health risks in 3D printing environments due to the emission of various chemicals. This systematic review and meta-analysis study aimed to investigate exposure to pollutants in 3D printing processes. A systematic search was conducted across five electronic bibliographic databases using three distinct keyword combinations. The researcher then screened the articles and selected those relevant to the study. Subsequently, data were extracted from these articles. The pooled concentrations were also computed by meta-analysis. A total of 137 articles were included in this study. The pollutants emitted by 3D printers encompass particles and aerosols, volatile organic compounds (VOCs), metals and fumes, carbonyl compounds, inorganic gases, and other compounds. The highest concentrations of particles were associated with powder and selective laser melting (SLM) processes, which could exceed permissible exposure levels. Among filaments, acrylonitrile-butadiene-styrene (ABS) and glycol-modified polyethylene terephthalate (PETG) filaments exhibited the highest concentrations of particles. Concentrations of all metals were below threshold limit value (TLV). However, the concentrations of carbonyls for polylactic acid (PLA) filaments and formaldehyde for acrylonitrile-butadiene-styrene (ABS) exceeded permissible exposure levels. While the concentrations of most VOCs were below TLV, the total volatile organic compounds (TVOC) concentrations for PLA, ABS, thermoplastic polyurethane (TPU), and glycol-modified polyethylene terephthalate (PETG) filaments were found to be higher than the permissible exposure level. These results indicate that the use of 3D printers may pose potential hazards to human health. Therefore, control measures, such as proper filtration and ventilation, should be implemented to safeguard the health of individuals.

由于各种化学物质的排放，人们对3D打印环境中潜在的健康风险一直感到担忧。这项系统回顾和荟萃分析研究旨在调查3D打印过程中污染物的暴露情况。使用三种不同的关键字组合在五个电子书目数据库中进行了系统的搜索。然后，研究人员筛选文章并选择与研究相关的文章。随后，从这些文章中提取数据。合并浓度也通过荟萃分析计算。本研究共纳入137篇文献。3D打印机排放的污染物包括颗粒和气溶胶、挥发性有机化合物（VOCs）、金属和烟雾、羰基化合物、无机气体和其他化合物。最高浓度的颗粒与粉末和选择性激光熔化（SLM）工艺有关，可能超过允许的暴露水平。在长丝中，丙烯腈-丁二烯-苯乙烯（ABS）和乙二醇改性聚对苯二甲酸乙二醇酯（PETG）长丝的颗粒浓度最高。所有金属的浓度均低于阈值。然而，聚乳酸（PLA）长丝的羰基浓度和丙烯腈-丁二烯-苯乙烯（ABS）的甲醛浓度超过了允许的暴露水平。虽然大多数挥发性有机化合物浓度低于TLV，但PLA、ABS、热塑性聚氨酯（TPU）和乙二醇改性聚对苯二甲酸乙二醇酯（PETG）长丝的总挥发性有机化合物（TVOC）浓度高于允许暴露水平。这些结果表明，使用3D打印机可能对人体健康造成潜在危害。因此，应采取适当的过滤和通风等控制措施，以保障个人的健康。

{"title":"A global evaluation of exposure to pollutants in 3D printing: A systematic review and meta-analysis","authors":"Amir Hossein Khoshakhlagh , Saleh Al Sulaie , Saeid Yazdanirad , Agnieszka Gruszecka-Kosowska","doi":"10.1016/j.hazadv.2025.100931","DOIUrl":"10.1016/j.hazadv.2025.100931","url":null,"abstract":"<div><div>Concerns persist regarding potential health risks in 3D printing environments due to the emission of various chemicals. This systematic review and meta-analysis study aimed to investigate exposure to pollutants in 3D printing processes. A systematic search was conducted across five electronic bibliographic databases using three distinct keyword combinations. The researcher then screened the articles and selected those relevant to the study. Subsequently, data were extracted from these articles. The pooled concentrations were also computed by meta-analysis. A total of 137 articles were included in this study. The pollutants emitted by 3D printers encompass particles and aerosols, volatile organic compounds (VOCs), metals and fumes, carbonyl compounds, inorganic gases, and other compounds. The highest concentrations of particles were associated with powder and selective laser melting (SLM) processes, which could exceed permissible exposure levels. Among filaments, acrylonitrile-butadiene-styrene (ABS) and glycol-modified polyethylene terephthalate (PETG) filaments exhibited the highest concentrations of particles. Concentrations of all metals were below threshold limit value (TLV). However, the concentrations of carbonyls for polylactic acid (PLA) filaments and formaldehyde for acrylonitrile-butadiene-styrene (ABS) exceeded permissible exposure levels. While the concentrations of most VOCs were below TLV, the total volatile organic compounds (TVOC) concentrations for PLA, ABS, thermoplastic polyurethane (TPU), and glycol-modified polyethylene terephthalate (PETG) filaments were found to be higher than the permissible exposure level. These results indicate that the use of 3D printers may pose potential hazards to human health. Therefore, control measures, such as proper filtration and ventilation, should be implemented to safeguard the health of individuals.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100931"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the toxic effects and mechanisms of polystyrene micro/nanoplastics across multiple animal species 聚苯乙烯微/纳米塑料对多种动物的毒性作用及其机制综述

IF 7.7 Q2 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials advances

Pub Date : 2025-11-01 DOI: 10.1016/j.hazadv.2025.100938

Jingjing Kong , Lihua Zhao , Qu Chen , Tingting Gao , Pingping Xu , Fanhua Sun , Chuanhui Zang , Lei Zhu , Qingli Zhang , Zichu Zhao , Tingting Tang , Yan Zhang , Hailong Li

Polystyrene (PS) plastics, known for their high light transmittance, transparency, electrical insulation, and low thermal conductivity, are extensively utilized in the production of foam packaging, building insulation materials, disposable tableware, and electrical products. Improper disposal of plastics and their degradation in the environment have led to the widespread presence of polystyrene micro/nanoplastics (PS MNPs) in the atmosphere, seawater, freshwater, soil, and food sources. This study systematically reviews the toxic effects of PS MNPs across various dimensions, with a particular focus on their impact on marine animals, freshwater animals, soil animals, terrestrial invertebrates, and mammals. The objective of this study is to elucidate the potential mechanisms of toxicity associated with PS MNPs and to investigate their effects on animals at the individual, organ, tissue, cellular, and molecular levels.

聚苯乙烯（PS）塑料以其高透光性、透明度、电绝缘性和低导热性而闻名，广泛应用于泡沫包装、建筑保温材料、一次性餐具和电气产品的生产。塑料的不当处理及其在环境中的降解导致聚苯乙烯微/纳米塑料（PS MNPs）广泛存在于大气、海水、淡水、土壤和食物来源中。本研究系统地回顾了PS MNPs在各个方面的毒性作用，特别关注它们对海洋动物、淡水动物、土壤动物、陆生无脊椎动物和哺乳动物的影响。本研究的目的是阐明与PS MNPs相关的潜在毒性机制，并从个体、器官、组织、细胞和分子水平研究它们对动物的影响。

{"title":"Review of the toxic effects and mechanisms of polystyrene micro/nanoplastics across multiple animal species","authors":"Jingjing Kong , Lihua Zhao , Qu Chen , Tingting Gao , Pingping Xu , Fanhua Sun , Chuanhui Zang , Lei Zhu , Qingli Zhang , Zichu Zhao , Tingting Tang , Yan Zhang , Hailong Li","doi":"10.1016/j.hazadv.2025.100938","DOIUrl":"10.1016/j.hazadv.2025.100938","url":null,"abstract":"<div><div>Polystyrene (PS) plastics, known for their high light transmittance, transparency, electrical insulation, and low thermal conductivity, are extensively utilized in the production of foam packaging, building insulation materials, disposable tableware, and electrical products. Improper disposal of plastics and their degradation in the environment have led to the widespread presence of polystyrene micro/nanoplastics (PS MNPs) in the atmosphere, seawater, freshwater, soil, and food sources. This study systematically reviews the toxic effects of PS MNPs across various dimensions, with a particular focus on their impact on marine animals, freshwater animals, soil animals, terrestrial invertebrates, and mammals. The objective of this study is to elucidate the potential mechanisms of toxicity associated with PS MNPs and to investigate their effects on animals at the individual, organ, tissue, cellular, and molecular levels.</div></div>","PeriodicalId":73763,"journal":{"name":"Journal of hazardous materials advances","volume":"20 ","pages":"Article 100938"},"PeriodicalIF":7.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145519685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0