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Conventional Medicinal Uses and Chemical Structure of Important Secondary Metabolites in the Genus Eremostachys: A Literature Review Eremostachs属植物的常规药用及重要次生代谢产物的化学结构
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.15
Amrendra M Khan
Genus Eremostachys Bunge is a key medicinal plant grown in Eastern Europe, Central and Western Asia and Middle East. The plants of this genus have numerous secondary metabolites, which exhibit both traditional and pharmacological applications. Eremostachys contains several classes of reactive chemical ingredients such as flavonoids (viz. Apigenin, Luteolin, Loasifolin, Loasin A, Apuleisin, Apigenin and Kaempferol etc), isoflavonoids (viz. Soforanarin B, Loasin B and Vicarin), iridoid glucosides (viz. Shanzhiside, Lamalbide, Lamalbidic acid, Epiloganin, Pulchelloside, Harpagide, Pulchelloside, hamighriprasin, Eremoside, Phloyoside and Barlerin etc.), phenylethanoid glycosides (viz. Verbascoside, Leucosceptoside A, and Echinacoside etc,), acids, hydrocarbons, terpenes, diterpenoids and sterols (viz. Eremostachiin, Phlomisoside II, Stigmasterol, β-Sitosterol, Daucosterol and Oleanolic aicd) etc. These metabolites are well known for their pharmacological applications such as antibacterial, anti-inflammatory, antioxidant, antirheumatic, anti-poisonous, antimalarial, anticancer, antimalarial, antiallergic, antiarthritic and antidepressant etc. Before the identification of chemical constituents, genus Eremostachys was used by few countries since ancient viz. by China, Iran, India, Pakistan, Tajakistan and few middle and south Asian countries etc. This genus has been used by people of these region since ancient as analgesic, anti-inflammatory, wound healing, ant-insecticidal, antiparasitic, antiallergic, liver care, joint pain, arthritis, antioxidant, antibacterial, antidepressant, antimalarial, perfumery, detergent, soap, beauty products. In India, E. superba has been used as a food for cattle to increase milk production. In the present review, the important traditional uses of some important species of the genus Eremostachys have been briefly discussed due to their availability and affordability. The number of medicinal and pharmacological applications of the plant genus Eremostachys are also summarized in the paper.
Eremostachs Bunge属是生长在东欧、中亚和西亚以及中东的重要药用植物。该属植物具有许多次生代谢产物,具有传统和药理学应用。Eremostachcs含有几类活性化学成分,如黄酮类化合物(即芹菜素、木犀草素、Loasifolin、Loasin A、Apuleisin、芹菜素和山奈酚等)、类黄酮类化合物,环烯醚萜苷(即山脂苷、拉马肽、拉马二酸、表马钱苷、羊肚菌苷、Harpagide、Pulchelloside、hamighriprasin、Eremoside、Phloyside和Barlerin等)、苯乙醇苷(即Verbascoside、Leucocceptoside A和Echinacide等)、酸、碳氢化合物、萜烯,二萜类和甾醇类化合物(Eremostachiin、Phloisoside II、Stigmasterol、β-西酞醇、Daucosterol和齐墩果酸aicd)等。这些代谢产物以其抗菌、抗炎、抗氧化、抗风湿、无毒、抗疟、抗癌、抗疟疾、抗变态反应、抗关节炎和抗抑郁等药理应用而闻名。在化学成分鉴定之前,Eremostachs属自古以来被少数国家使用,即中国、伊朗、印度、巴基斯坦、塔吉克斯坦和少数中南亚国家等。该属自古以来就被这些地区的人们用作镇痛、抗炎、伤口愈合、蚂蚁杀虫、抗寄生虫、抗过敏、护肝、关节疼痛,关节炎,抗氧化剂,抗菌,抗抑郁,抗疟,香水,洗涤剂,肥皂,美容产品。在印度,超级大肠杆菌被用作养牛的食物,以提高牛奶产量。在本综述中,由于Eremostachs属的一些重要物种的可用性和可负担性,简要讨论了它们的重要传统用途。本文还综述了该属植物的药用和药理应用。
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引用次数: 0
Restorative Effects of Capsaicin Encapsulated Chitosan Nanoparticles on Chemically-Induced Hormone Receptor-Positive Mammary Carcinoma in Sprague-Dawley Rats 辣椒素包封壳聚糖纳米颗粒对Sprague-Dawley大鼠化学诱导的激素受体阳性乳腺癌的恢复作用
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.39
D. Kalaiyarasi
The clinical use of capsaicin has been confined due to its low-grade solubility and frail bioavailability. So, we examined the impact of capsaicin encapsulated chitosan nanoparticles (CAP@CS-NP) on chemically induced hormone receptor-positive mammary carcinoma. The mammary tumor was induced by a single dose of 7,12-Dimethylbenz(a)anthracene (DMBA) 25mg/kg b.wt. injected subcutaneously near the mammary gland. After 7 weeks, CAP@CS-NP 4mg/kg b.wt. was administered orally to tumor-bearing rats. Furthermore, sex hormones levels, ER and PR expression, mast cell population, and molecular docking studies were carried out. Tumor-bearing rats flashed significantly hoisted levels of sex hormones, mast cell population, ER, and PR expression. Administration of CAP@CS-NP 4mg/kg b.wt. restored the levels of sex hormones, mast cell population, ER, and PR expression to near-normal levels. Additionally, molecular docking revealed good binding affinity and best glide scores. These findings suggest that nano encapsulation of CAP@CS-NP 4mg/kg b.wt. administration can regulate hormonal expression to treat hormone receptor-positive mammary carcinoma
辣椒素的临床应用由于其低溶解度和脆弱的生物利用度而受到限制。因此,我们研究了辣椒素包封的壳聚糖纳米颗粒(CAP@CS-NP)对化学诱导的激素受体阳性乳腺癌的影响。7,12-二甲基苯(a)蒽(DMBA) 25mg/kg b.wt单剂量诱导乳腺肿瘤。在乳腺附近皮下注射。7周后CAP@CS-NP 4mg/kg b.wt。给荷瘤大鼠口服。此外,还进行了性激素水平、ER和PR表达、肥大细胞群和分子对接研究。荷瘤大鼠的性激素、肥大细胞数量、ER和PR表达水平显著升高。给药CAP@CS-NP 4mg/kg b.w.t。使性激素水平、肥大细胞数量、ER和PR表达恢复到接近正常水平。此外,分子对接显示出良好的结合亲和力和最佳的滑翔分数。这些结果表明纳米包封CAP@CS-NP 4mg/kg b.wt。通过给药调节激素表达来治疗激素受体阳性乳腺癌
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引用次数: 0
Comparing Anti-Inflammatory, Anti-protease Activities and Untargeted Metabolite Profiling Based on Ultra-Performance Liquid Chromatography-Mass Spectroscopy of Five Memecylon species from Western Ghats Karnataka, India 基于超高效液相色谱-质谱法比较印度卡纳塔克邦西高止山脉五种Memecylon的抗炎、蛋白酶活性和非靶向代谢产物谱
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.18
Bharathi T R
Memecylon umbellatum, M. edule, M. talbotianum, M. malabaricum, and M. wightii species belong to the family Melastomataceae. The genus is well-known traditional medicinal herb used to treat skin diseases. The goal is to compare the metabolite makeup of the five Memecylon spp. and to evaluate the extract's anti-inflammatory and antiprotease activities. UPLC-ESI-QTOF-MS was used to profile untargeted metabolites in a water/methanol extract, followed by statistical analysis with PCA and HCA. Anti-inflammatory and antiprotease activity were determined by inhibiting soybean 15-lipoxygenase and Protease. Phenols and flavonoids are the most abundant secondary metabolites in Memecylon spp. Principal component analysis (PCA) was used to identify marker chemicals from five species, tocopherol, isorhamnetin 3-glucoside, isothalic acid, stearoylglycerol, and pyrrolidine. The Memecylon spp. maybe clustered into two groups based on principal component analysis, with M. malabaricum & M. wightii clustered together and M. umbellatum, M. edule & M. talbotianum forming another clustered. The anti-inflammatory (Soybean 15-lipoxygenase inhibition) and antiprotease activities (Trypsin and thrombin Inhibition) of crude extracts suggested that M. malabaricum and M. talbotianum extracts exhibited higher inhibition compared to the other three species. These data suggest that differences in metabolite profiles might be connected to differences in the bioactivity of the five plant extracts examined. The untargeted UPLC-ESI-QTOF-MS technique is efficient for identifying bioactive components of Memecylon spp.
伞形密梭兰(Memecylon umbellatum)、密梭兰(M. edule)、密梭兰(M. talbotianum)、密梭兰(M. malabaricum)和密梭兰(M. wightii)属于密梭科。该属是著名的传统草药,用于治疗皮肤病。目的是比较五种米梭兰的代谢物组成,并评价其提取物的抗炎和抗蛋白酶活性。采用UPLC-ESI-QTOF-MS分析水/甲醇提取物中的非靶向代谢物,然后用PCA和HCA进行统计分析。通过抑制大豆15-脂氧合酶和蛋白酶测定抗炎和抗蛋白酶活性。利用主成分分析(PCA)对5个种的生育酚、异鼠李素3-葡萄糖苷、异thalic酸、硬脂酰甘油和吡啶进行了鉴定。根据主成分分析,Memecylon属可分为两个类群,M. malabaricum和M. wightii聚在一起,M. umbellatum、M. edule和M. talbotianum聚在一起。粗提物的抗炎活性(抑制大豆15-脂氧合酶)和抗蛋白酶活性(抑制胰蛋白酶和凝血酶)表明,malabaricum和M. talbotianum提取物比其他3种具有更高的抑制作用。这些数据表明,代谢物谱的差异可能与所研究的五种植物提取物的生物活性差异有关。非靶向UPLC-ESI-QTOF-MS技术是一种高效的生物活性成分鉴定方法。
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引用次数: 0
Differential Effects of Solvents on Extraction, Pharmacognostic Evaluation and Antioxidant Activity of Long Pepper Piper longum Fruit Extract 不同溶剂对长椒果实提取物提取、生药学评价及抗氧化活性的影响
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.26
A. Mittal
The present study proposed differential effect of solvents on extraction, pharmacognostic evaluation and antioxidant activity of Long pepper (Piper longum) fruit extract. The bio-analytes present in P. longum fruit were extracted by dissolving powder fruit in water, ethanol, methanol, acetone, and ethyl acetate. Further, the extracts were dried using rotavapor at 55 °C and used to assess the phytochemical analysis where total phenolic compounds (TPCs) were evaluated using Folin-Ciocalteu Assay. Additionally, ascorbic acid content was measured, and Fourier Transform Infrared Spectroscopy (FTIR) analysis was performed to predict the presence of various compounds based on their surface functional groups. Further, antioxidant efficiency was determined by considering DPPH radical scavenging activity. The quantitative measurements of the TPC and ascorbic acid reveal the presence of the pharmacognostic compounds in P. longum, which is also supported by FTIR analysis. The FC assay test confirmed the highest polyphenols (181.0 ± 8.69 mg GAE/g) in ethyl acetate extract, while methanolic extract showed the maximum ascorbic acid content (1.51 ± 0.067 mg AE/g). Methanolic and ethyl acetate-based extraction process showed great results than other solvents as they showed maximum DPPH radical scavenging activity (% degradation), 81.57 %, followed by ethyl acetate (79.35%). The obtained results announced P. longum extract can be used as a raw material in pharmaceutical industries and local levels to improve health conditions.
研究了不同溶剂对辣椒果实提取物提取、生药学评价和抗氧化活性的影响。采用水、乙醇、甲醇、丙酮和乙酸乙酯溶解法提取了长叶果粉末中的生物分析物。此外,提取液在55°C下使用旋蒸干燥,并用于评估植物化学分析,其中使用Folin-Ciocalteu Assay评估总酚化合物(TPCs)。此外,测定了抗坏血酸的含量,并进行傅里叶变换红外光谱(FTIR)分析,根据其表面官能团预测各种化合物的存在。此外,通过考虑DPPH自由基清除活性来确定抗氧化效率。TPC和抗坏血酸的定量测定结果表明,龙骨中存在生药学成分,FTIR分析也证实了这一结论。乙酸乙酯部位多酚含量最高(181.0±8.69 mg AE/g),甲醇部位抗坏血酸含量最高(1.51±0.067 mg AE/g)。甲醇和乙酸乙酯萃取法对DPPH自由基的清除率最高,达到81.57%,其次是乙酸乙酯(79.35%)。研究结果表明,龙葵提取物可作为制药工业和地方一级的原料,以改善卫生条件。
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引用次数: 0
Dimensions of Quality in Healthcare: Perceptions of Patients from Saudi Public Hospitals 医疗保健质量的维度:沙特公立医院患者的看法
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.13
Muhammad Attar
Healthcare quality is driven by multiple dimensions. The present study aimed to examine the main dimensions of healthcare quality from the perspective of patients in the Kingdom of Saudi Arabia public (KSA) hospitals. A patient satisfaction survey was designed to discover the perceived dimensions of quality in the KSA healthcare sector. The steps involved in identifying the quality dimensions relating to healthcare are presented in the paper. The principal component analysis (PCA) lead to identifying the components with total variance explained and result in identifying three meta dimensions. This included wellness support, compliance with Standard, and exceptional service and immediate care. The research findings have provided a platform for emerging and discovering patient needs, direct improvement efforts in such a critical service sector and can be used as a basis for developing new measures to discover patients’ needs.
医疗质量是由多个维度驱动的。本研究旨在从沙特阿拉伯王国公立医院(KSA)患者的角度考察医疗质量的主要方面。一项患者满意度调查旨在发现KSA医疗保健部门的质量感知维度。本文介绍了识别与医疗保健相关的质量维度所涉及的步骤。主成分分析(PCA)导致识别具有解释的总方差的成分,并导致识别三个元维度。这包括健康支持、遵守标准、卓越服务和即时护理。研究结果为发现和发现患者需求提供了一个平台,直接改善了这一关键服务部门的工作,并可作为制定新措施以发现患者需求的基础。
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引用次数: 0
Production of Total Reducing Sugars from Bambusa balcooa through Oxalic Acid Pretreatment 草酸预处理生产竹总还原糖的研究
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.36
S. Sivamani
This study aims to assess the applicability of organic acid pretreatment on culm of Bambusa balcooa for the production of maximum total reducing sugars. The experiments were performed by varying organic acids (Formic, acetic, pyruvic, maleic, malic, tartaric, adipic, citric and oxalic acids), concentration of oxalic acid (1-4% (w/v)), solvent to solid ratio (5-40 mL/g), pretreatment time (0-60 min) and temperature (75-135 0C) to maximize total reducing sugars (TRS) concentration using fractional factorial design based one-factor-at-a-time (OFAT) approach. Total reducing sugars concentration was estimated by using 3,5-dinitro salicylic acid (DNSA) method. Among various organic acids, oxalic acid exhibited higher reducing sugars concentration. The optimal values show that the maximum TRS of 48.33 g/L was achieved at oxalic acid concentration, solvent to solid ratio, time and temperature of 3% (w/v), 10 mL/g, 15 min and 121 0C for the pretreatment of cassava stem with oxalic acid. A low value of coefficient of variation (CV = 0.32%) showed that the optimal conditions were validated by experiments. Thus, B. balcooa could be used as a potential feedstock for the production of TRS by organic acid pretreatment.
本研究旨在评估有机酸预处理对斑竹秆生产最大总还原糖的适用性。通过改变有机酸(甲酸、乙酸、丙酮酸、马来酸、苹果酸、酒石酸、己二酸、柠檬酸和草酸)、草酸浓度(1-4%(w/v))、溶剂与固体的比例(5-40mL/g)、,预处理时间(0-60分钟)和温度(75-135℃),以使用基于分数因子设计的一次一因子(OFAT)方法最大化总还原糖(TRS)浓度。用3,5-二硝基水杨酸(DNSA)法测定总还原糖浓度。在各种有机酸中,草酸的还原糖浓度较高。最佳值表明,草酸预处理木薯茎,在草酸浓度、溶剂固比、时间和温度为3%(w/v)、10mL/g、15min和121 0C时,TRS最高可达48.33g/L。变异系数低(CV=0.32%)表明,实验验证了最佳条件。因此,B.balcooa可作为通过有机酸预处理生产TRS的潜在原料。
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引用次数: 0
Carvacrol Prevents Bisphenol A-Induced Behavioral Changes And Oxidative Stress in Zebrafish Through Modulating Brain Antioxidant Defense Mechanism Carvacrol通过调节大脑抗氧化防御机制预防双酚A诱导的斑马鱼行为变化和氧化应激
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.40
Bichandarkoil Jayaram Pratima
It has been discovered that bisphenol A (BPA), an established anthropogenic xenoestrogen, is a causal factor in developing cancer, cognitive impairment, neurotoxicity, oxidative stress, and other harmful effects in humans and other species. Although there is some research into the mechanisms of BPA-induced toxicity, it is unclear whether there is a chance of amelioration through natural intervention. Zebrafish (Danio rerio) were used in this study after waterborne exposure to BPA, to assess whether carvacrol co-supplementation could reduce the destructive potential of the compound. All the chemicals and reagents utilized in the current investigations were purchased from Sigma-Aldrich, Ottochem, India. 5-7month-old zebrafish were acquired from a local fish store in Kolathur, Chennai and kept in a 50-L tank at a constant temperature of 25±2ºC. There were no animal ethical issues involved to carry out this research. Laboratory studies were conducted to determine whether the antioxidant nature of carvacrol might protect the zebrafish brain from BPA-induced altered behavioural responses and oxidative stress. The current data demonstrates that carvacrol is effective in alleviating the altered behavioural response caused by BPA. Biochemical investigations in the zebrafish brain suggest that carvacrol may have therapeutic potential in treating oxidative stress induced by BPA. In addition, the zebrafish brain is protected by carvacrol against BPA-induced toxicity. These preliminary data suggest that carvacrol may be a helpful intervention in treating BPA-induced toxicity in zebrafish by inhibiting the reactive oxygen species production. Novel therapeutic approaches for treating BPA-induced predisposition to severe illnesses could emerge from future research on signaling cascades.
人们发现,双酚A(BPA)是一种公认的人为外源性雌激素,是人类和其他物种发生癌症、认知障碍、神经毒性、氧化应激和其他有害影响的原因之一。尽管对BPA诱导毒性的机制有一些研究,但尚不清楚是否有通过自然干预改善的机会。斑马鱼(Danio rerio)在水性接触BPA后被用于本研究,以评估共同补充香芹酚是否可以降低该化合物的破坏潜力。目前调查中使用的所有化学品和试剂均购自印度奥托切姆的Sigma-Aldrich。5-7个月大的斑马鱼是从金奈科拉图尔当地的一家鱼类商店获得的,并保存在50升的恒温箱中,温度为25±2ºC。开展这项研究不涉及动物伦理问题。进行了实验室研究,以确定香芹酚的抗氧化性质是否可以保护斑马鱼的大脑免受BPA诱导的行为反应和氧化应激的影响。目前的数据表明,香芹酚能有效缓解BPA引起的行为反应改变。对斑马鱼大脑的生化研究表明,香芹酚在治疗BPA诱导的氧化应激方面可能具有治疗潜力。此外,香芹酚保护斑马鱼的大脑免受BPA诱导的毒性。这些初步数据表明,香芹酚可能通过抑制活性氧的产生,对治疗BPA诱导的斑马鱼毒性有帮助。未来对信号级联的研究可能会出现治疗BPA诱导的严重疾病易感性的新治疗方法。
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引用次数: 0
Synthesis and Application of Latex-Based Ethylene-Propylene Copolymer on Methacrylic Acid 甲基丙烯酸乳液基乙烯-丙烯共聚物的合成及应用
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.9
Shixaliyev Kerem Seyfi
The latex synthesis in the presence of ethylene-propylene copolymer and methacrylic acid (MAA) was considered for this experiment. The kinetic regularities of the synthesis process were determined and the optimal quantities and ratios of the components were determined both experimentally and by mathematical modeling. It was determined that a modified latex with optimal values ​​is obtained when the amount of methacrylic acid in the latex is 5 parts by weight. The absorbent composition was prepared latex-based based on synthesized EPC – + methacrylic acid. The prepared absorbent was impregnated with viscose (22B) and 222K kapron cord and a rubber-cord bond were determined. The findings of the present study show that the aqueous dispersions of EPC latex were synthesized using various emulsifiers with high technological stability. The presence of the main factors affecting the stability and adhesive properties of the EPC aqueous dispersion has been established. It has been shown that the best stability for 6 months is achieved at a pH value of 12.EPC water emulsion was modified in the presence of MAA by graft copolymerization.
本实验考虑了乙烯-丙烯共聚物和甲基丙烯酸(MAA)存在下的乳胶合成。确定了合成过程的动力学规律,并通过实验和数学建模确定了各组分的最佳用量和配比。确定了当甲基丙烯酸的加入量为5份(重量比)时,得到的改性胶乳的最佳值。在合成EPC - +甲基丙烯酸的基础上制备了乳液基的吸水性组合物。用粘胶(22B)和222K卡普纶线浸渍所制得的吸附剂,并测定了胶绳黏结。研究结果表明,采用多种乳化剂合成的EPC乳液水分散体具有较高的工艺稳定性。确定了影响EPC水分散体稳定性和粘接性能的主要因素。研究表明,在pH值为12时,可达到6个月的最佳稳定性。采用接枝共聚法在MAA存在下对EPC水乳状液进行改性。
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引用次数: 0
Population Status, Distribution, Threats and Conservation of Blackbuck Antilope cervicapra in South Asia: An Updated Literature Review 南亚黑羚的种群现状、分布、威胁与保护:最新文献综述
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.3
Rabia Tahir
Blackbuck, Antilope cervicapra, is a diurnal ungulate species with distinct sexual dimorphism and spellbinding beauty. Male blackbuck has mesmeric beauty with its unique darker coat, showing the increased intensity of color with age. Blackbuck is endemic to Pakistan, Nepal, India and Bangladesh but now its population is reduced to a few areas. Threats such as hunting, stress, habitat loss, diseases, poaching, road accidents, habitat fragmentation, interspecific competition, predation pressure etc., have reduced the population size of blackbuck to a threatened level. Therefore, different conservation strategies are underway to increment its count for improvement of faunal diversity, tourism development and dispersal of the local culture in South Asia. Captive breeding of species is the most efficacious conservation strategy in South Asia so far. Furthermore, various rules and regulations along with strategies like hormone-mediated conservation by injections of prostaglandin and artificial insemination are assisting the species by increasing its birth rate. Genetic studies, introduction to non-endemic but suitable habitat and religious affiliation of communities also contributed to blackbuck conservation. Current conservation practices are helping to conserve the blackbuck but are associated with a few concerns also, thereby proper management, planning, monitoring of conservation practices is required. Population size, distribution range, threats confronted by species, conservation practices and recommendations have been discussed in this article, which will help in advancement of work in this area.
黑鹿是一种昼夜活动的有蹄类动物,具有明显的两性异形和迷人的美丽。雄性黑鹿有着迷人的美丽,它独特的深色皮毛,随着年龄的增长,颜色越来越强烈。黑鸭是巴基斯坦、尼泊尔、印度和孟加拉国的地方病,但现在它的人口减少到了几个地区。狩猎、压力、栖息地丧失、疾病、偷猎、道路事故、栖息地破碎化、种间竞争、捕食压力等威胁已将黑嘴鹬的种群规模降至受威胁的水平。因此,不同的保护策略正在进行中,以增加其数量,从而改善南亚的动物多样性、旅游业发展和当地文化的传播。圈养物种是南亚迄今为止最有效的保护策略。此外,各种规则和条例,以及通过注射前列腺素和人工授精进行激素介导的保护等策略,都有助于提高该物种的出生率。遗传研究、引入非地方性但合适的栖息地以及社区的宗教信仰也有助于黑尾鹬的保护。目前的保护措施有助于保护黑背蟾蜍,但也与一些问题有关,因此需要对保护措施进行适当的管理、规划和监测。本文讨论了种群规模、分布范围、物种面临的威胁、保护实践和建议,这将有助于推进该领域的工作。
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引用次数: 1
Brucellosis: An Investigation of the Knowledge, Attitudes and Behaviors Among a Selected Population in Majmaah Saudi Arab 布鲁氏菌病:沙特阿拉伯马吉马选定人群的知识、态度和行为调查
Pub Date : 2022-03-25 DOI: 10.21786/bbrc/15.1.35
Mohammed A Alaidarous
Brucellosis is a zoonotic bacterial disease carried by animals such as sheep, cows, and camels. It is transmitted to humans through the consumption of affected animals or their by-products. Dairy products form a major part of the Arabic diet and are very widely consumed in Saudi Arabia, where brucellosis is endemic. This study has analyzed the current knowledge, attitudes, and behaviors toward brucellosis of adults aged 18 years and older among Majmaah University students and staff. A cross-sectional study with 181 participants was conducted using an online survey during March–April 2021. The results showed that the majority of people knew about brucellosis and its transmission, but only a fraction of them took the required precautionary measures. This study highlights that knowledge alone is insufficient to promote healthy behaviors. It is thus important to raise awareness in a way that can convert knowledge into action.
布鲁氏菌病是一种由绵羊、奶牛和骆驼等动物携带的人畜共患细菌性疾病。它通过食用受影响的动物或其副产品传播给人类。乳制品是阿拉伯人饮食的主要组成部分,在布鲁氏菌病流行的沙特阿拉伯消费非常广泛。本研究分析了马吉马大学学生和教职员工中18岁及以上成年人对布鲁氏菌病的当前知识、态度和行为。2021年3月至4月,通过在线调查对181名参与者进行了横断面研究。结果表明,大多数人都知道布鲁氏菌病及其传播,但只有一小部分人采取了必要的预防措施。这项研究强调,仅靠知识不足以促进健康行为。因此,重要的是以一种能够将知识转化为行动的方式提高认识。
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引用次数: 0
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Bioscience Biotechnology Research Communications
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