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Bacterial richness enhances the thermostability of soil organic matter via a long-term trade-off between molecular diversity and thermodynamic stability 细菌丰富度通过分子多样性和热力学稳定性之间的长期权衡来增强土壤有机质的热稳定性
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-18 DOI: 10.1038/s43016-025-01253-5
Meng Wu, Emanuele Lugato, Pengfa Li, Jia Liu, Cunpu Qiu, Shuang Wang, Xingzhu Ma, Xiaoyu Hao, Ming Liu, Jun Shan, Xiaoyuan Yan, Zhongpei Li
The persistence of soil organic matter (SOM) is shaped by its molecular features and stability, but the temporal dynamics of these features remain unclear. Here we investigate the molecular diversity (the number of molecules) and molecular thermodynamic stability (the theoretical Gibbs free energy for the half reaction of carbon oxidation) of SOM in soils from long-term (>30 years) paddy and upland experimental fields. Thermogravimetric analysis shows that enhanced SOM thermostability aligns with the temporal variation of molecular thermodynamic stability in these soils. Increased SOM molecular thermodynamic stability occurs alongside decreased molecular diversity over decades, and this temporal trade-off (negative relationship) is modulated by increased bacterial richness. These findings highlight the role of microbial diversity in enhancing SOM thermostability and support strategies that promote bacterial richness for improved SOM persistence in agriculture. Soil organic matter stability is critical for long-term soil health and carbon sequestration. This study reveals that increased bacterial richness enhances soil organic matter thermostability by driving a trade-off between molecular diversity and thermodynamic stability.
土壤有机质(SOM)的持久性是由其分子特征和稳定性决定的,但这些特征的时间动态尚不清楚。本文研究了长期(>;30年)水田和旱田土壤中SOM的分子多样性(分子数量)和分子热力学稳定性(碳氧化半反应的理论吉布斯自由能)。热重分析表明,SOM热稳定性的增强与土壤分子热力学稳定性的时间变化一致。几十年来,SOM分子热力学稳定性的增加与分子多样性的减少同时发生,这种时间权衡(负相关关系)被细菌丰富度的增加所调节。这些发现强调了微生物多样性在提高SOM热稳定性中的作用,并支持了促进细菌丰富度以提高SOM在农业中的持久性的策略。土壤有机质稳定性对土壤长期健康和固碳至关重要。该研究表明,细菌丰富度的增加通过驱动分子多样性和热力学稳定性之间的权衡来增强土壤有机质的热稳定性。
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引用次数: 0
Time unlocks bovine fibroblast immortality to pave the way for cultivated beef 时间开启了牛成纤维细胞的不朽,为培育牛肉铺平了道路
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-17 DOI: 10.1038/s43016-025-01256-2
We demonstrate that bovine fibroblasts can undergo spontaneous immortalization after 500 days in culture, without genetic modification or p53 inactivation. These rare events provide a safe, stable and economically viable cell source that overcomes key barriers to cultivated beef production.
我们证明牛成纤维细胞在培养500天后可以进行自发永生化,而不需要基因修饰或p53失活。这些罕见的事件提供了一种安全、稳定和经济上可行的细胞来源,克服了养殖牛肉生产的主要障碍。
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引用次数: 0
Oat protein nanofibrils as a plant-based solution for iron fortification 燕麦蛋白纳米原纤维作为植物性铁强化溶液
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-17 DOI: 10.1038/s43016-025-01265-1
Food fortified with iron has the potential to correct iron deficiency and associated anaemia, yet it remains challenging to ensure acceptable iron absorption without compromising the sensory properties of the modified food. Stable oat protein nanofibrils carrying ultrasmall iron nanoparticles deliver highly bioavailable iron with minimal changes in colour and taste, offering a promising strategy for global iron fortification.
含铁强化食品有可能纠正缺铁和相关贫血,但在不影响改性食品感官特性的情况下确保可接受的铁吸收仍然具有挑战性。稳定的燕麦蛋白纳米原纤维携带超小的铁纳米颗粒,在颜色和味道变化极小的情况下提供高度生物可利用的铁,为全球铁强化提供了一种有前途的策略。
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引用次数: 0
Adjustments, evidence and political tensions in the US Supplemental Nutrition Assistance Program 美国补充营养援助计划中的调整、证据和政治紧张局势
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-13 DOI: 10.1038/s43016-025-01258-0
Vincenzina Caputo, David R. Just
The Supplemental Nutrition Assistance Program (SNAP) plays a key role in the US food system. As Congress considers major changes to it under the 2025 One Big Beautiful Bill Act and states propose restrictions on what benefits may be used to purchase food, SNAP sits at the intersection of food security, labour market policy and public health. Drawing on historical experience and empirical economic evidence, we assess the impact of the proposed changes on SNAP, showing that specific policy solutions could improve outcomes without increasing programme costs, while simplified enrolment procedures could increase programme participation and reduce food insecurity. Recent policy changes in the USA have reignited long-standing debates surrounding the Supplemental Nutrition Assistance Program (SNAP). This Review assesses the potential impact of these changes and identifies priorities for further improving SNAP’s effectiveness and reach.
补充营养援助计划(SNAP)在美国食品系统中起着关键作用。随着国会考虑根据《2025年一个大美丽法案》(2025 One Big Beautiful Bill Act)对该计划进行重大修改,以及各州提出限制可用于购买食品的福利,SNAP处于食品安全、劳动力市场政策和公共卫生的交叉点。根据历史经验和经验性经济证据,我们评估了拟议的变化对SNAP的影响,表明具体的政策解决方案可以在不增加计划成本的情况下改善结果,而简化的登记程序可以增加计划参与并减少粮食不安全。美国最近的政策变化重新点燃了长期以来围绕补充营养援助计划(SNAP)的争论。本审查评估了这些变化的潜在影响,并确定了进一步提高SNAP有效性和覆盖面的优先事项。
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引用次数: 0
Spontaneous immortalization of bovine fibroblasts following long-term expansion offers a non-transformed cell source for cultivated beef 牛成纤维细胞在长期扩增后的自发永生为培养牛肉提供了一种非转化细胞来源
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-12 DOI: 10.1038/s43016-025-01255-3
Laura Pasitka, Merav Cohen, Shaun Regenbaum, Avner Ehrlich, Boaz Gildor, Ariel Gold, Yaakov Nahmias
Spontaneously immortalized cell lines provide an essential, non-transformed resource for cultivated meat production. Although chicken fibroblasts readily immortalize in culture, bovine fibroblasts have not been shown to immortalize without genetic manipulation of TP53 or TERT. Here we demonstrate the spontaneous immortalization of fibroblast lines from Simmental and Holstein cows. We track the molecular basis of the immortalization process over 500 days of culture, corresponding to 240 population doublings. Cells entered senescence at population doubling 60, showing γH2AX foci, telomere shortening and an active senescence-associated secretory phenotype profile. Breakthroughs occurred following 400 days in culture, resulting in stable fibroblast lines. Telomerase and PGC1A activation during senescence resolve telomere shortening and mitochondrial dysfunction without activating P53, driving spontaneous immortalization. We explored the economic potential of cultivated beef production using spontaneously immortalized bovine fibroblasts, showing that price parity could be theoretically reached using continuous manufacturing. Bovine fibroblast cell line generation without genetic modification is characterized. A technoeconomic analysis demonstrates the potential for price-competitive, scaled-up cultivated beef production.
自发永生化细胞系为养殖肉类生产提供了必不可少的非转化资源。虽然鸡的成纤维细胞很容易在培养中长生不老,但牛的成纤维细胞在没有TP53或TERT基因操纵的情况下并没有表现出长生不老。在这里,我们展示了西门塔尔奶牛和荷尔斯坦奶牛成纤维细胞系的自发永生。在500天的培养过程中,我们追踪了永生过程的分子基础,相当于240个种群加倍。细胞在群体倍增60时进入衰老,显示出γ - h2ax焦点,端粒缩短和活跃的衰老相关分泌表型。培养400天后出现突破,形成稳定的成纤维细胞系。衰老过程中端粒酶和PGC1A的激活解决了端粒缩短和线粒体功能障碍,而不激活P53,从而驱动自发的永生。我们探索了利用自发永生牛成纤维细胞培育牛肉生产的经济潜力,表明使用连续生产在理论上可以达到价格平价。牛成纤维细胞系的产生没有基因修饰的特点。一项技术经济分析显示了具有价格竞争力的大规模养殖牛肉生产的潜力。
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引用次数: 0
Complexity and uncertainty in future food system transformation modelling 未来食品系统转型模型的复杂性和不确定性
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-10 DOI: 10.1038/s43016-025-01257-1
Enayat A. Moallemi, Adam C. Castonguay, Daniel Mason-D’Croz, Rohan Nelson, Wolfgang Britz, Cameron Allen, Michalis Hadjikakou, Michael Battaglia, Brett A. Bryan, Costanza Conti, Raymundo Marcos-Martinez, Stefan Frank, Duy Nong, Sibel Eker, Saman Razavi, Javier Navarro-Garcia, Lei Gao
Food systems face multi-dimensional pressures and require integrated assessments of environmental, social, health and economic dimensions to inform their transformation. Although economic equilibrium models and integrated assessment models have been instrumental in this context, future decision-making requires more diverse and inclusive participatory processes. Here we evaluate the ability of current models to represent food systems and identify challenges and opportunities regarding key aspects of their transformative change, including socio-political dynamics and human–nature feedbacks, links between global and local scales, robustness under uncertainty, as well as evolving stakeholder demands. Our analysis underscores the need to rethink how models are designed and used for a more effective integration into decision-making processes. Food system transformations need nuanced approaches to modelling future outcomes. This Review explores current challenges and outlines paths forward for food system transformation modelling, with an emphasis on diversification of the approaches used and integration into decision-making processes.
粮食系统面临多方面的压力,需要对环境、社会、卫生和经济方面进行综合评估,以便为其转型提供信息。虽然经济均衡模型和综合评估模型在这方面发挥了作用,但未来的决策需要更加多样化和包容性的参与性进程。在这里,我们评估了当前模型代表粮食系统的能力,并确定了其变革的关键方面的挑战和机遇,包括社会政治动态和人类-自然反馈,全球和地方尺度之间的联系,不确定性下的稳健性,以及不断变化的利益相关者需求。我们的分析强调需要重新思考如何设计和使用模型,以便更有效地整合到决策过程中。粮食系统转型需要细致入微的方法来模拟未来的结果。本综述探讨了当前的挑战,并概述了粮食系统转型建模的前进道路,重点是所使用方法的多样化和纳入决策过程。
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引用次数: 0
Oat protein nanofibril–iron hybrids offer a stable, high-absorption iron delivery platform for iron fortification 燕麦蛋白纳米原纤维-铁杂交种为铁强化提供了稳定、高吸收的铁传递平台
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-10 DOI: 10.1038/s43016-025-01260-6
Jiangtao Zhou, Sueppong Gowachirapant, Christophe Zeder, Alexander Wieczorek, Jeannette Nuessli Guth, Ines Kutzli, Sebastian Siol, Ferdinand von Meyenn, Michael B. Zimmermann, Raffaele Mezzenga
Iron deficiency and anaemia affect two billion people globally. Iron fortification can help to treat anaemia, but most current fortificants are limited by low absorption and/or poor sensory properties. Here we introduce oat protein nanofibrils (OatNF) carrying ultrasmall iron nanoparticles that are engineered to carry iron in ferrous or ferric form. In a prospective cross-over stable-isotope absorption trial in young iron-deficient women (n = 52), OatNF reduced with sodium ascorbate carried mainly ferrous iron and showed high fractional absorption with water and with polyphenol-rich food, showing 1.76- and 1.65-fold higher absorption, respectively, compared with ferrous sulfate. When sodium hydroxide was used as the reducing agent, OatNF carried mainly ferric iron, which was also well absorbed and featured good sensory properties in reactive food matrices. OatNF hybrids offer a plant-based strategy for delivering highly bioavailable iron for food fortification. Nanofibrils constructed from oat protein and carrying iron nanoparticles can increase absorption compared with ferrous sulfate in human studies, offering a promising fortification strategy for treating iron deficiency and improving human nutrition.
全球有20亿人缺铁和贫血。铁强化可以帮助治疗贫血,但大多数目前的强化剂受到低吸收和/或感官特性差的限制。在这里,我们介绍了燕麦蛋白纳米原纤维(OatNF)携带的超小铁纳米颗粒,这种纳米颗粒被设计成以亚铁或铁的形式携带铁。在一项针对年轻缺铁女性(n = 52)的前瞻性交叉稳定同位素吸收试验中,抗坏血酸钠减少了OatNF,主要携带亚铁,与水和富含多酚的食物相比,其吸收率分别高出1.76倍和1.65倍。当使用氢氧化钠作为还原剂时,OatNF主要携带三铁,在反应性食品基质中也具有良好的吸收和良好的感官性能。燕麦- nf杂交提供了一种基于植物的策略,为食品强化提供高度生物可利用的铁。
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引用次数: 0
Changing paradigms through practice 通过实践改变范式
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-07 DOI: 10.1038/s43016-025-01262-4
Juliana Gil
While the need to transform food and agriculture through a systemic approach may seem obvious, how to do it given siloed policies and structures is unclear. Corinna Hawkes, Director of the Division of Agrifood Systems and Food Safety for the UN Food and Agriculture Organization, builds on real-world examples to show that overcoming these barriers is possible where there is focus and intention.
虽然通过系统方法转变粮食和农业的必要性似乎是显而易见的,但在孤立的政策和结构的情况下,如何做到这一点尚不清楚。联合国粮食及农业组织农业粮食系统和食品安全司司长Corinna Hawkes以现实世界的例子为基础,表明只要有重点和意愿,克服这些障碍是可能的。
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引用次数: 0
Food systems boundaries are currently poorly defined 粮食系统的边界目前界定不清
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-06 DOI: 10.1038/s43016-025-01263-3
Paul Behrens, Joseph Poore
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引用次数: 0
Unstable supply and future shortages of wild forage fish heighten risks to global fed aquaculture production 野生饲料鱼供应不稳定和未来短缺加剧了全球饲料水产养殖生产的风险
IF 21.9 Q1 FOOD SCIENCE & TECHNOLOGY Pub Date : 2025-11-04 DOI: 10.1038/s43016-025-01254-4
Yue Liu, Ziyu Jiang, Richard S. Cottrell, Michael F. Tlusty, Kevin Fitzsimmons, Ling Cao
Aquaculture sector growth is challenged by feed constraints, particularly the erratic availability and cost of fishmeal and oil from wild forage fish. Limited attention is given to the risks that forage fish shortfalls pose to aquaculture feed supplies. Here we develop a shortfall impact model to investigate the effects of varying forage fish supply scenarios on global fed aquaculture. Results suggest fisheries management interventions and persistent climate impact could reduce forage fish catches by 4.5% to 19.4%, resulting in an 8% to 35.2% decline in fed aquaculture production. Countries cultivating carnivorous species and leading aquaculture-producing nations are most affected. To sustain production, 1.8 million tonnes of alternative ingredients annually will be required, highlighting the urgent need for cost-effective alternatives to ensure resilience. Fishmeal and oil derived from forage fish are critical vulnerabilities for stable aquaculture feed supply. A shortfall impact model and scenario analysis explores options for bridging forage fish deficits with alternative aquaculture feeds.
水产养殖部门的增长受到饲料限制的挑战,特别是野生饲料鱼鱼粉和鱼油的供应和成本不稳定。人们对饲料鱼短缺对水产养殖饲料供应造成的风险关注有限。在此,我们建立了一个短缺影响模型来研究不同饲料鱼供应情景对全球饲料水产养殖的影响。结果表明,渔业管理干预和持续的气候影响可使饲料鱼捕获量减少4.5% ~ 19.4%,导致饲料水产养殖产量下降8% ~ 35.2%。养殖食肉物种的国家和主要水产养殖生产国受到的影响最大。为了维持生产,每年将需要180万吨替代原料,这突出表明迫切需要具有成本效益的替代品来确保抵御能力。从饲料鱼中提取的鱼粉和鱼油是稳定水产养殖饲料供应的关键漏洞。短缺影响模型和情景分析探讨了用替代水产养殖饲料弥补饲料鱼短缺的选择。
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引用次数: 0
期刊
Nature food
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