This review article examines the current state of plastic waste and pollution, in particular in the form of marine litter, as it affects the goal of sustainable development and is affected by global North-South dynamics. The rise in plastic waste has had a deleterious effect on local populations and ecosystems, and remains a problem with numerous governance challenges, posing constraints to achieving the United Nations Sustainable Development Goals. This crisis is analyzed under the lens of global North-South dynamics, as the consequences for different nations differ in regard to their capacity to cope with waste, and other inequality issues. China’s decision to stop serving as the world’s central recycling location has pushed plastic waste exports into other Asian countries, and COVID-19 responses have utilized large quantities of plastic products. However, localized initiatives that involve non-governmental actors are making some headway in countries such as Brazil. This review article introduces the problem, examines extant literature linking plastic pollution with the United Nations’ Sustainable Development Goals, offers a brief Brazilian case study of a coordinated response, outlines key research gaps and needs, and articulates the concept of plastic justice as a progressive normative design and framework for further analysis.