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Chronic pruritus in geriatric inpatients : A descriptive pilot study on a guideline-compliant basic topical treatment. 老年住院患者的慢性瘙痒:一项符合指南的基本局部治疗的描述性试点研究。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2026-01-31 DOI: 10.1007/s00391-026-02553-6
Carole Elisabeth Berens, Amir S Yazdi, L Cornelius Bollheimer, Thea Laurentius, David Kluwig

Background: Chronic pruritus (CP) is a prevalent condition in older adults, with a significant impact on the quality of life (QoL), yet data on CP in German geriatric inpatients are scarce.

Objective: The study provides descriptive data on the prevalence and severity of CP and its impact on QoL and psychological well-being in cognitively capable geriatric inpatients. Furthermore, the study appraises the feasibility and adherence of a 2-month lipid-enriched emollient treatment, as recommended in current guidelines, with a view to informing and optimizing care for this vulnerable group.

Material and methods: The present pilot study constitutes a prospective, single-center, observational study. Participants were recruited from a geriatric hospital ward in Germany. Over 2 months the cream was to be applied twice daily. Severity, QoL and psychological well-being were assessed before and after the intervention using three validated questionnaires, the Hospital Anxiety and Depression Scale (HADS), the Dermatology Life Quality Index (DLQI) and the Working Group Pruritus Research (Arbeitsgemeinschaft Pruritusforschung, AGP) questionnaire. The data on the geriatric assessment scores, medication and previous illnesses were taken from the medical records.

Results: Among 214 hospitalized patients, 8.4% had CP. After 2 months, all median scores improved: the HADS anxiety and depression from 6 to 3.5 or 4.5, the numeric rating scale (NRS) of the worst pruritus from 7 to 5.5 and the DLQI from 3 to 1.

Conclusion: Despite suboptimal scores in the geriatric assessment, the intervention led to an overall improvement in pruritus severity, QoL and psychological well-being.

背景:慢性瘙痒症(CP)是老年人的常见病,对生活质量(QoL)有重大影响,但德国老年住院患者的CP数据很少。目的:研究认知能力老年住院患者CP患病率、严重程度及其对生活质量和心理健康的影响。此外,该研究评估了当前指南中推荐的2个月富脂润肤治疗的可行性和依从性,以期为这一弱势群体提供信息和优化护理。材料和方法:本初步研究为前瞻性、单中心、观察性研究。参与者是从德国一家老年医院病房招募的。在2个月的时间里,每天使用两次乳霜。采用医院焦虑抑郁量表(HADS)、皮肤病生活质量指数(DLQI)和瘙痒症研究工作组(Arbeitsgemeinschaft Pruritusforschung, AGP)三份有效问卷评估干预前后的严重程度、生活质量和心理健康状况。老年评估得分、用药和既往疾病的数据取自医疗记录。结果:214例住院患者中,CP发生率为8.4%。2个月后,所有患者的中位评分均有所改善:HADS焦虑和抑郁从6分提高到3.5分或4.5分,最严重瘙痒的数值评定量表(NRS)从7分提高到5.5分,DLQI从3分提高到1分。结论:尽管老年评估得分不理想,但干预导致瘙痒严重程度,生活质量和心理健康的总体改善。
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引用次数: 0
[New prognosis models for geriatric patients]. [老年患者的新预后模型]。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2026-01-29 DOI: 10.1007/s00391-026-02554-5
Lejla Sacic
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引用次数: 0
Prof. Dr. Peter Oster : Zum Gedenken. Peter Oster教授:Zum Gedenken。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-24 DOI: 10.1007/s00391-026-02565-2
William Micol, Jürgen M Bauer, Michael Denkinger
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引用次数: 0
Mitteilungen der Jungen Geriatrie der DGG. DGG青年老年病学通讯。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 DOI: 10.1007/s00391-026-02557-2
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引用次数: 0
Mitteilungen des BV Geriatrie. 英国老年病学协会。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 DOI: 10.1007/s00391-026-02560-7
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引用次数: 0
Erratum to: Perioperative fluid management in older trauma patients. 老年创伤患者围手术期液体处理的勘误。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 DOI: 10.1007/s00391-026-02564-3
Carla Stenmanns, Cynthia Olotu, Mirja Katrin Modreker, Stefan Grund, Beatrice Heck
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引用次数: 0
[The Munich street work project "Senior citizens visited by experts in the community" (SAVE)-A mixed methods evaluation study]. [慕尼黑街道工作项目“社区专家拜访老年人”(SAVE)-混合方法评价研究]。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2025-08-04 DOI: 10.1007/s00391-025-02477-7
Hanna Klingshirn, Laura Wehr

Background: Old age and service centers (ASZ) in Munich offer preventive and care services for older people. As initiating contact with existing support services is a barrier, the street work project "Senior citizens visited by experts in the community" (SAVE) was introduced. Since 2019 SAVE experts have been providing advice to older people who are in public spaces and appear to be in need of support. The aim of our study was to examine the implementation of SAVE to identify recommendations for action.

Method: The SAVE evaluation is based on a mixed methods multistage design with a participatory approach. Firstly, secondary data (SAVE statistics, project documents) were analyzed. In addition, participant observations (n = 4), a focus group (n = 6) and interviews with SAVE experts (n = 4) and ASZ managers (n = 5) were conducted. To integrate the data the respective results were compared, triangulated and jointly interpreted.

Results: According to the statistics (period: January 2020-June 2023) the project reached 1546 people (57% women, 2847 contacts). Common problems identified included physical and mental illnesses, financial difficulties and loneliness. The derived recommendations for action address the following topics: SAVE requirements profile, basic equipment, implementation, orientation phase, public awareness and collegial cooperation.

Conclusion: The SAVE project offers an innovative way of reaching older people in their community by providing information, building relationships, giving on-site counselling and providing additional support. The project can be seen as an important measure to prevent distress among older people.

背景:慕尼黑的老年和服务中心(ASZ)为老年人提供预防和护理服务。由于与现有的支援服务接触是一个障碍,因此我们推出了“社区专家探访长者”的街头工作项目。自2019年以来,SAVE的专家一直在为公共场所中似乎需要支持的老年人提供建议。我们研究的目的是检查SAVE的实施情况,以确定行动建议。方法:SAVE评估是基于混合方法的多阶段设计与参与式方法。首先,对二手数据(SAVE统计数据、项目文件)进行分析。此外,还进行了参与者观察(n = 4)、焦点小组(n = 6)和SAVE专家(n = 4)和ASZ管理人员(n = 5)的访谈。为了整合数据,对各自的结果进行了比较、三角测量和联合解释。结果:据统计(期间:2020年1月- 2023年6月),项目达到1546人(女性57%,接触者2847人)。常见的问题包括身体和精神疾病、经济困难和孤独。所得的行动建议涉及下列主题:节约资源的要求、概况、基本设备、执行、定向阶段、公众认识和学院合作。结论:SAVE项目提供了一种创新的方式,通过提供信息、建立关系、提供现场咨询和提供额外支持来接触社区中的老年人。该项目可被视为防止老年人痛苦的一项重要措施。
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引用次数: 0
[Challenges and potential of geriatric research in Germany-Insights from the GERisearch survey]. [德国老年病学研究的挑战和潜力-来自GERisearch调查的见解]。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2025-11-26 DOI: 10.1007/s00391-025-02528-z
Bendix Labeit, Maela Caudal, Varvara Moskiou, Stefan Grund, Thea Laurentius, Johannes Trabert, Olaf Krause, Anna Maria Affeldt, Maximilian König

Background: High-quality contributions to international aging research and the advancement of geriatrics in Germany require physicians who are both clinically and scientifically active.

Objective: Investigation of the research activity, research interests and research conditions of physicians working in geriatrics in Germany, in order to identify the scientific potential, structural barriers and areas in need of support.

Material and methods: In a nationwide online cross-sectional survey, data were collected on the professional situation, and research activity, as well as research interests and obstacles.

Results: Among 273 participants one third were scientifically active, one third not interested and one third fundamentally interested but currently inactive. The largest proportion of scientifically active participants (47%) worked at university hospitals with a chair in geriatrics, where the highest research satisfaction was reported. The most frequently cited barrier was the limited compatibility of clinical work and research (49%). At nonuniversity hospitals without a chair in geriatrics many participants were interested in research but inactive and workplace-related obstacles predominated (55%). Men more often held a doctoral degree or habilitation and were more often active in research. Women accounted for two thirds of interested but inactive participants in research and expressed particular interest in polypharmacy (59%) and nutritional medicine (40%).

Discussion: Targeted measures are needed to strengthen geriatric research in Germany, particularly to support women and physicians at nonuniversity institutions. Key strategies include mentoring, protected research time and expansion of chairs in geriatrics. Despite structural barriers, interest in research remains high.

背景:对国际老龄化研究的高质量贡献和德国老年病学的进步需要临床和科学活跃的医生。目的:调查德国老年医学医生的研究活动、研究兴趣和研究状况,以确定其科学潜力、结构性障碍和需要支持的领域。材料与方法:在全国范围内进行在线横断面调查,收集专业现状、研究活动、研究兴趣和障碍等数据。结果:在273名参与者中,三分之一的人在科学上活跃,三分之一的人不感兴趣,三分之一的人根本感兴趣,但目前不活跃。从事科学活动的参与者中,最大比例(47%)在大学医院工作,并担任老年病学主席,据报道,那里的研究满意度最高。最常被提及的障碍是临床工作和研究的有限兼容性(49%)。在没有老年医学职位的非大学医院,许多参与者对研究感兴趣,但不活跃和工作场所相关的障碍占主导地位(55%)。男性通常拥有博士学位,并且更积极地从事研究。在对研究感兴趣但不积极的参与者中,女性占三分之二,她们对综合药学(59%)和营养医学(40%)特别感兴趣。讨论:需要有针对性的措施来加强德国的老年病学研究,特别是支持非大学机构的妇女和医生。关键策略包括指导、保护研究时间和扩大老年病学的教授名额。尽管存在结构性障碍,但人们对研究的兴趣仍然很高。
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引用次数: 0
[Pharmacokinetics and pharmacodynamics of anti-Parkinson drugs in geriatric patients : Key for optimization of treatment]. 老年患者抗帕金森药物的药代动力学和药效学:优化治疗的关键。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2026-02-19 DOI: 10.1007/s00391-026-02558-1
Marija Djukic, Sandra Schütze, Elisabeth Yoshida-Stiksrud, Orkhan Ismayilov, Roland Nau

Levodopa in combination with a decarboxylase inhibitor has an elimination half-life (t1/2) in older people of 1.8 h. The pharmacokinetics are complex and depend on galenics, body weight, sex, gastrointestinal motility and accompanying diseases. Levodopa plasma concentrations after oral dosing vary intraindividually and interindividually. The decarboxylase inhibitors benserazide and carbidopa possess different t1/2. In advanced Parkinson's disease, intrajejunal levodopa or subcutaneous foslevodopa combined with a decarboxylase inhibitor infusion can maintain constant levodopa plasma levels during daytime. To rapidly reach steady state, an adequate morning bolus is required. Absorption and elimination of entacapone and opicapone are similar to levodopa. Entacapone as a reversible catechol O‑methyltransferase (COMT) inhibitor must be administered concomitant to levodopa. Opicapone as irreversible COMT inhibitor is administered once daily at night. Rasagiline and selegiline are irreversible inhibitors of monoamine oxidase B. Therefore, in spite of their short t1/2 they are dosed once daily. Absorption of rasagiline is independent of meals. Clinically established dopamine agonists activate D1/D5 dopamine motor receptors less strongly than the dopaminergic receptors of D2/D3/D4group. This is a probable reason for their numerous adverse effects particularly in older people with Parkinson's disease.

左旋多巴联合脱羧酶抑制剂在老年人中的消除半衰期(t1/2)为1.8 h。药代动力学是复杂的,依赖于galenics,体重,性别,胃肠运动和伴随疾病。口服左旋多巴后的血浆浓度在个体内和个体间有所不同。脱羧酶抑制剂苯塞拉肼和卡比多巴具有不同的t1/2。在晚期帕金森病患者中,空肠内左旋多巴或皮下左旋多巴联合脱羧酶抑制剂输注可在白天维持恒定的左旋多巴血浆水平。为了迅速达到稳定状态,需要在早晨服用足够的剂量。恩他卡彭和阿帕卡彭的吸收和消除与左旋多巴相似。恩他卡酮作为可逆的儿茶酚O甲基转移酶(COMT)抑制剂必须与左旋多巴同时使用。Opicapone作为不可逆的COMT抑制剂,每天晚上给药一次。雷沙吉兰和塞来吉兰是单胺氧化酶b的不可逆抑制剂,因此,尽管它们的半周期很短,但它们每天服用一次。雷沙吉兰的吸收与饮食无关。临床证实的多巴胺激动剂对D1/D5多巴胺运动受体的激活程度低于D2/D3/ d4组的多巴胺能受体。这可能是它们产生大量副作用的原因,尤其是对患有帕金森病的老年人。
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引用次数: 0
Reasons for long-term care need: analyzing combinations of health limitations in Germany. 长期护理需求的原因:分析德国健康限制因素的组合。
IF 1 4区 医学 Q4 GERIATRICS & GERONTOLOGY Pub Date : 2026-03-01 Epub Date: 2025-09-23 DOI: 10.1007/s00391-025-02498-2
Martin Wetzel, Andrea Cass, Johanna Schütz

Background: Health limitations affect long-term care (LTC) needs differently. For instance, people with cognitive limitations require more organizational support, whereas those with functional limitations require more personal care. While the impact of singular health limitations on LTC has been widely studied, little attention has been given to the prevalences of co-occurring health limitations that drive LTC needs.

Objectives: Our exploratory study seeks to address the gap in understanding the prevalence of multiple, intertwining health limitations that contribute to the need for LTC.

Materials and methods: We used data from the German Medical Service (MD). The MD assesses LTC needs and assigns care grades, which serve as the basis for LTC insurance benefits. The available data contains all assessments in 2019 of adults living in Bavaria (the largest state in Germany), focusing on those with first-time LTC needs (N = 101,227). Using latent class analysis, we identified combinations of limitations across six health dimensions (e.g., mobility, cognition).

Results: Among first-time LTC recipients, 5 distinct classes of care needs were identified. Two classes reflect single limitations: mobility limitations, and the need for assistance with medical therapy. Three classes point to various combinations of limitations. While classes differed in size, they also varied significantly by age, gender, and care grade.

Conclusion: The co-occurrence of health limitations is not an exception but a central feature of LTC needs even at the initial stages of dependency, emphasizing the importance of tailored care strategies. These insights can help local authorities and care providers offer targeted LTC services more strategically.

背景:健康限制对长期护理(LTC)需求的影响不同。例如,有认知限制的人需要更多的组织支持,而有功能限制的人则需要更多的个人照顾。虽然单一健康限制对长期服务的影响已被广泛研究,但很少关注共同发生的健康限制的患病率,这些限制推动了长期服务的需求。目的:我们的探索性研究旨在解决在理解多种相互交织的健康限制的流行方面的差距,这些限制有助于LTC的需求。材料和方法:我们使用来自德国医疗服务(MD)的数据。MD评估长期护理服务的需求并分配护理等级,这是长期护理服务保险福利的基础。现有数据包含2019年对居住在巴伐利亚州(德国最大的州)的成年人的所有评估,重点是首次有LTC需求的人(N = 101,227)。使用潜在类别分析,我们确定了六个健康维度(例如,活动能力、认知能力)的局限性组合。结果:在首次LTC接受者中,确定了5种不同的护理需求。有两个类别反映了单一的限制:行动能力的限制,以及需要医疗援助。有三个类指向限制的各种组合。虽然班级规模不同,但年龄、性别和护理等级也有显著差异。结论:即使在依赖的初始阶段,健康限制的共同出现也不是例外,而是长期护理需求的核心特征,这强调了量身定制护理策略的重要性。这些见解可以帮助地方当局和护理提供者更具战略性地提供有针对性的LTC服务。
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引用次数: 0
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Zeitschrift Fur Gerontologie Und Geriatrie
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