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2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)最新文献

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Miniaturized HPLC column with nano-pore beads for protein separation on flexible medical implants 用于柔性医用植入物蛋白质分离的微型纳米孔珠高效液相色谱柱
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4432980
Yongmo Yang, J. Chae
This paper reports a miniaturized HPLC (high performance liquid chromatography) column packed with nano-pore beads for flexible medical implants applications. The all-flexible-polymer column capable of integrating with micro/nano-devices on a chip separates biological entities to relax stringent requirements on subsequent detectors and to enable parallel detection in a detector array. The fabricated device has successfully separated a protein mixture using nano-pore beads in a miniaturized column. According to HPLC analysis, the intensity ratio of large to small protein varies significantly, more than a factor of 300, over sample collecting time, ~12mins, suggesting very high separation performance.
本文报道了一种用于柔性医疗植入物的纳米孔珠填充的小型化高效液相色谱柱。全柔性聚合物柱能够与芯片上的微/纳米器件集成,分离生物实体,从而放松对后续探测器的严格要求,并实现探测器阵列的并行检测。该装置利用纳米孔珠在微型化柱中成功分离了蛋白质混合物。根据HPLC分析,大蛋白与小蛋白的强度比变化显著,大于300倍,样品采集时间为~12min,表明分离性能非常高。
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引用次数: 2
Microreactions using nanoliter droplets with oil encapsulation 微反应用纳升液滴油包封
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433019
Chuang-yuan Lee, Hongyu Yu, E. S. Kim
This paper reports a microreaction technology for biochemical assay using nanoliter droplets encapsulated inside oil droplets. Microreaction chambers are constructed on a glass substrate by accumulating oil droplets that are dispensed by the directional droplet ejector. Droplets of different aqueous reagents are then directionally ejected into the oil microchambers for parallel and combinatory analysis. Because the reagents are encapsulated in oil, the evaporation rate is greatly reduced, and only small amount of reagents are required. The microchamber size and reagent amount are digitally controlled by the number of ejected oil and reagent droplets, respectively. Ejectors for oil and reagents have been integrated on a single chip so that each assay is performed efficiently without any mechanical movement and alignment. We have carried out both physical and chemical microreactions with this method, and observed negligible difference (in response) from conventional macroreactions.
本文报道了一种将纳升液滴包裹在油滴内进行生化检测的微反应技术。微反应室是通过积聚由定向液滴喷射器分配的油滴在玻璃基板上构建的。然后将不同含水试剂的液滴定向喷射到油微室中进行平行和组合分析。由于试剂被包裹在油中,蒸发速度大大降低,只需要少量的试剂。微室尺寸和试剂量分别通过喷射油滴数和试剂滴数进行数字控制。用于油和试剂的喷射器已集成在单个芯片上,因此每次分析都有效地执行,而无需任何机械运动和校准。我们已经用这种方法进行了物理和化学微反应,并且观察到与常规宏观反应的差异可以忽略不计(响应)。
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引用次数: 4
Embedded self-circulation of liquid fuel for a micro direct methanol fuel cell 微型直接甲醇燃料电池中液体燃料的嵌入式自循环
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433020
D. D. Meng, C. Kim
This paper introduces a micro direct methanol fuel cell (muDMFC) with an embedded self-pumping mechanism to deliver liquid fuel. The fuel is propelled by the CO2 bubbles generated by the fuel-cell electrochemical reaction, and the bubbles are removed from the system during the self-pumping process. Furthermore, the pumping rate is self- regulated by the reaction, i.e., by the electric load. By eliminating the need for a pump and gas/liquid separator, our design allows much simpler fuel-cell systems, which is especially beneficial for miniaturization. Although we test with muDMFC in this paper, the mechanism applies to other membrane electrode assembly (MEA)-based fuel cells with organic liquid fuels as well.
本文介绍了一种内置自抽送机构的微型直接甲醇燃料电池(muDMFC)。燃料由燃料电池电化学反应产生的CO2气泡推进,气泡在自抽气过程中从系统中去除。此外,泵送速率是由反应,即由电负荷自我调节的。通过消除对泵和气液分离器的需求,我们的设计使燃料电池系统变得更加简单,这对小型化特别有利。虽然我们在本文中测试了muDMFC,但该机制也适用于其他基于膜电极组件(MEA)的有机液体燃料燃料电池。
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引用次数: 12
Smart brush based on a high density CMOS stress sensor array and SU-8 microposts 基于高密度CMOS应力传感器阵列和SU-8微柱的智能刷
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433163
P. Gieschke, J. Held, M. Doelle, J. Bartholomeyczik, P. Ruther, O. Paul
This paper reports on a CMOS integrated stress sensor array combined with SU-8 posts fabricated on the chip surface. The chip contains an array of 1024 field effect transistor (FET)-based stress sensors occupying a total area of ca. 1 x 1 mm2. On-chip circuitry is used for sensor addressing, signal amplification, A/D conversion, signal processing, and serial bus communication. A novel scalable matrix-based sensor selection concept enables the integration of high-density stress sensor arrays with minimum wiring. The system significantly expands previous stress sensor arrays in terms of an increased number of sensors and reduced sensor pitch. An array of 8 x 8 circular SU-8 posts with a diameter of 62 mum and a height of 300 mum was fabricated on the CMOS chips. The new brush-like device was used for measuring vertical and horizontal force distributions.
本文报道了一种结合SU-8柱的CMOS集成应力传感器阵列。该芯片包含1024个基于场效应晶体管(FET)的应力传感器阵列,占据总面积约为1 x 1 mm2。片上电路用于传感器寻址、信号放大、A/D转换、信号处理和串行总线通信。一种新颖的可扩展的基于矩阵的传感器选择概念,使高密度应力传感器阵列的集成与最少的布线。该系统在增加传感器数量和减小传感器间距方面显著扩展了以前的应力传感器阵列。在CMOS芯片上制备了直径为62 μ m,高度为300 μ m的8 × 8圆形SU-8柱阵列。该新型刷状装置用于测量垂直和水平方向的力分布。
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引用次数: 12
Design and fabrication of an artificial skin using PI-copper films 使用pi -铜薄膜的人造皮肤的设计与制造
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433149
Ming-Yuan Cheng, W.-Y. Chang, L. Tsao, S.-A. Yang, Y. Yang, W. Shih, F. Chang, S. Chang, K. Fan
This paper presents the design, fabrication and measurement of a flexible 8 times 8 temperature and tactile sensing array which will be used as the artificial skin for robot applications. The temperature and pressure sensing elements are heterogeneously integrated on a flexible copper-PI film using micromachining techniques. The tactile sensing elements are fabricated by dispensing conductive polymer on the pre-defined inter-digital copper electrodes. Discrete temperature sensor chips are employed as the temperature sensing elements. Scanning circuits are implemented and experimental results are also provided.
本文介绍了一种柔性的8 × 8温度和触觉传感阵列的设计、制造和测量,该阵列将用作机器人的人造皮肤。采用微加工技术将温度和压力传感元件异质集成在柔性铜- pi薄膜上。触觉传感元件是通过在预先定义的数字间铜电极上分配导电聚合物来制造的。采用离散式温度传感器芯片作为温度传感元件。实现了扫描电路,并给出了实验结果。
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引用次数: 23
Rapid synthesis of carbon nanotubes by bulk and localized inductive heating 本体和局部感应加热快速合成碳纳米管
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433096
B. D. Sosnowchik, Liwei Lin
In this work, we report a rapid yet simple methodology for the synthesis of carbon nanotubes (CNTs) in a room temperature environment using an inductive heating system with either a) bulk synthesis on silicon chips, or b) local synthesis on suspended MEMS structures. This setup enables growth and integration of CNTs with MEMS structures in a matter of 1-2 minutes. For bulk synthesis, high growth rates of up to 200 mum/min were obtained, resulting in growth of vertically aligned CNTs with an average diameter of 6.8nm. Integration from bulk- grown CNTs on MEMS structures resulted in lower resistances from larger diameter CNTs. Localized synthesis and integration was also obtained on suspended copper microstructures, illustrating an ohmic CNT response with a resistance of 110 kOmega. The breadth of synthesis and integration capabilities enabled by inductive heating illustrates a new class of rapid synthesis for vapor-liquid-solid-grown nanostructures.
在这项工作中,我们报告了一种在室温环境下使用感应加热系统快速而简单地合成碳纳米管(CNTs)的方法,其中a)硅片上的整体合成或b)悬浮MEMS结构上的局部合成。这种设置可以在1-2分钟内实现碳纳米管与MEMS结构的生长和集成。对于体合成,获得了高达200 mum/min的高生长速率,从而生长出平均直径为6.8nm的垂直排列的碳纳米管。大块生长的碳纳米管在MEMS结构上的集成导致更大直径碳纳米管的电阻更低。在悬浮铜微结构上也获得了局部合成和集成,说明了电阻为110 kOmega的欧姆碳纳米管响应。通过感应加热实现的合成和集成能力的广度说明了一种新型的蒸汽-液体-固体生长纳米结构的快速合成。
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引用次数: 7
Mechanical characterization of silicon nitride thin-films using microtensile specimens with integrated 2D diffraction gratings 利用集成二维衍射光栅的微拉伸试样对氮化硅薄膜进行力学表征
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4432964
J. Gaspar, Y. Nurcahyo, P. Ruther, O. Paul
This paper reports on the mechanical characterization of microtensile specimens made of silicon nitride (SiNx) thin-films with integrated 2D reflective gratings. By applying an axial force, the structures respond mechanically with an elongation and contraction in the longitudinal and transversal directions, respectively. The corresponding variations of both periods of the grating are monitored in real time by measuring the diffraction pattern resulting from the illumination of the grating with monochromatic light. The strain components are thus evaluated locally in the structure. By integrating such an optical technique with an efficient test structure previously developed, the extraction of materials' Young's modulus E, Poisson's ratio nu, residual strain epsivres and stress sigmares and fracture strength sigma0 is in principle made possible from the measurement of a single test structure. Here we demonstrate the extraction of E, epsivres, sigmares and sigma0 of the nitride films.
本文报道了集成二维反射光栅的氮化硅(SiNx)薄膜微拉伸试样的力学特性。通过施加轴向力,结构在纵向和横向上分别产生伸长和收缩的机械反应。通过测量单色光照射光栅产生的衍射图,实时监测光栅两个周期的相应变化。因此,应变分量在结构中被局部评估。通过将这种光学技术与先前开发的高效测试结构相结合,原则上可以从单个测试结构的测量中提取材料的杨氏模量E、泊松比nu、残余应变系数和应力信号以及断裂强度sigma0。在这里,我们演示了氮化膜的E, epsivres,信号和sigma0的提取。
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引用次数: 8
Small, soft, and safe microactuator for retinal pigment epithelium transplantation 小、软、安全的视网膜色素上皮移植微致动器
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433083
Yusaku Watanabe, Masanori Maeda, N. Yaji, R. Nakamura, H. Iseki, M. Yamato, T. Okano, Sadao Hori, Satoshi Konishi
This paper proposes a novel surgical tool for the retinal pigment epithelium (RPE) sheet transplantation. The proposed tool employs the principle of pneumatic balloon actuator (PBA). It is possible to design small, soft and safe surgical tool by using PBA because PBA is made of PDMS and driven by pneumatic pressure. These distinctive characteristics of PBA are attractive for such a challenging surgery as the RPE sheet transplantation in an eyeball. The designed head size of tool is 3 mm times 3 mm times 100 mum by taking account of the size of the RPE sheet (3 mm times 3 mm). The developed tool can perform sequential motions through independent control of different PBA so as to introduce and transplant the RPE sheet to an eyeball. Generated force by the movement of the transplantation tool is measured around 3 mN, which is allowable in an eyeball. Experimental results of both in vitro and in vivo test by using the developed tool will be reported to demonstrate feasibility of our strategy.
本文提出一种新的视网膜色素上皮(RPE)片移植手术工具。该工具采用气动球囊执行器(PBA)的工作原理。由于PBA由PDMS制成,由气压驱动,因此PBA可以设计出小巧、柔软、安全的手术工具。PBA的这些独特特征对于眼球内RPE片移植这样具有挑战性的手术是有吸引力的。考虑到RPE板材的尺寸(3mm × 3mm),设计的刀具头尺寸为3mm × 3mm × 100 mm。所开发的工具可以通过独立控制不同的PBA进行顺序运动,从而将RPE片引入眼球并移植到眼球上。移植工具运动产生的力约为3mn,这在眼球中是允许的。将报告使用开发的工具进行体外和体内测试的实验结果,以证明我们的策略的可行性。
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引用次数: 48
Two approaches to micromachining si heat exchanger for Joule-Thomson cryosurgical probes 焦耳-汤姆逊冷冻探针硅热交换器微加工的两种方法
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433062
Weibin Zhu, M. White, D. W. Hoch, G. Nellis, S. Klein, Y. Gianchandani
This paper describes results from two types of micromachined recuperative heat exchangers intended for Joule-Thomson (J-T) cryosurgical probes, which require high stream-to-stream thermal conductance while restricting parasitic stream-wise (axial) conduction. In design A, rows of fins composed of high conductivity silicon are bonded onto a 100 mum thick base plate composed of low conductivity Pyrex glass. This planar device has a footprint of 6times1.5 cm2 and 2.5 mm thickness, and is fabricated using a 5-mask process. In design B, numerous high-conductivity silicon plates alternating with low-conductivity Pyrex spacers are stacked together. This has a footprint of 1times1cm2, a length of 1.4 cm, and is fabricated using a 3-mask process. Preliminary experiments show that the primary performance constraint for design A is imposed by the compromise between mechanical robustness and transverse conductance of the thin glass base plate that separates the high pressure and low pressure streams. Design B enhances the robustness of the device and can sustain higher pressure.
本文描述了用于焦耳-汤姆逊(J-T)冷冻探针的两种类型的微机械回热式热交换器的结果,这两种类型的热交换器需要高流到流的导热性,同时限制寄生流方向(轴向)传导。在设计A中,一排排由高导电性硅组成的鳍片粘合在100毫米厚的由低导电性耐热玻璃组成的底板上。该平面器件的占地面积为6倍1.5 cm2,厚度为2.5 mm,采用5掩模工艺制造。在设计B中,大量的高导电性硅片与低导电性的耐热玻璃间隔片交替堆叠在一起。它的占地面积为1乘以1平方厘米,长度为1.4厘米,并使用3掩模工艺制造。初步实验表明,设计A的主要性能约束是在分离高压流和低压流的薄玻璃基板的机械稳健性和横向电导之间的折衷。设计B增强了装置的坚固性,可以承受更高的压力。
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引用次数: 7
Tensile-mode fatigue tests and fatigue life predictions of single crystal silicon in humidity controlled environments 湿度控制环境下单晶硅拉伸疲劳试验及疲劳寿命预测
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433142
Y. Yamaji, K. Sugano, O. Tabata, T. Tsuchiya
This paper reports on a tensile-mode fatigue test in a constant humidity, even in a very high humidity, to reveal the mechanism of fatigue fractures of MEMS materials. A newly developed tensile-mode fatigue tester using the electrostatic grip can control the humidity from 25% RH to 90% RH. Using this tester, the fatigue life and strength of single crystal silicon (SCS) thin films and their dependence on the humidity were evaluated. In addition, using the statistical analysis for the fatigue test results, the fatigue parameter of SCS was obtained. The scale parameter, Weibull modulus, and fatigue parameter in the high humidity (85-90% RH) were 2.9times109 Pa, 13.6, and 86.3, respectively. With these parameters, the fatigue life prediction of SCS was performed for the long-term reliability assessment of MEMS devices.
为了揭示MEMS材料的疲劳断裂机理,本文报道了在恒湿度甚至极高湿度条件下的拉伸疲劳试验。新开发的一种采用静电握把的拉伸型疲劳测试仪,可将湿度控制在25% RH ~ 90% RH之间。利用该测试仪对单晶硅薄膜的疲劳寿命和强度及其与湿度的关系进行了研究。此外,通过对疲劳试验结果的统计分析,得到了SCS的疲劳参数。高湿条件下(85 ~ 90% RH)的尺度参数、威布尔模量和疲劳参数分别为2.9倍109 Pa、13.6倍和86.3倍。利用这些参数,对SCS进行疲劳寿命预测,对MEMS器件进行长期可靠性评估。
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引用次数: 13
期刊
2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)
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