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2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)最新文献

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Mass production of uniform alginate capsules for micro cell encapslation using micro chamber array 微室阵列微细胞包封用海藻酸盐均匀胶囊的批量生产
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433112
H. Kitagawa, Wei-heong Tan, S. Takeuchi
This work is motivated by the need for accurate positioning of both adherent and non-adherent cells into arrays that can be integrated with microfluidic channels in high-throughput screening (HTS) for drug discovery. We describe a microfluidic device that allows rapid production of uniform micro hydrogel capsules that can contain cells. Up to 1times104 hydrogel capsules can be simply formed and arrayed simultaneously using microchambers in a 10 mm long microchannel. In this work, alginate was used as the hydrogel capsules that can be dissolved and removed with EDTA; thus samples confined in the capsules are collectable after observation in the array. We demonstrated the microencapsulation of E. coli into alginate capsules, and dissolved the capsules with EDTA successfully.
这项工作的动机是需要将贴壁细胞和非贴壁细胞精确定位到阵列中,这些阵列可以在高通量筛选(HTS)中与微流控通道集成,用于药物发现。我们描述了一种微流体装置,可以快速生产均匀的微水凝胶胶囊,可以包含细胞。在10毫米长的微通道中使用微室可以同时简单地形成和排列多达1times104个水凝胶胶囊。本研究以海藻酸盐为水凝胶胶囊,采用EDTA溶解去除;因此,在阵列中观察后,可以收集密闭在胶囊中的样品。我们演示了将大肠杆菌微胶囊化成海藻酸盐胶囊,并成功地将胶囊与EDTA溶解。
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引用次数: 2
A two-axis piezoelectric tilting micromirror with a newly developed PZT-meandering actuator 两轴压电倾斜微镜与新开发的pzt弯曲驱动器
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4432994
M. Tani, M. Akamatsu, Y. Yasuda, H. Toshiyoshi
In this paper, we propose a new mechanical design of piezoelectric unimorph actuator that generate large static deflection angle by accumulating angular displacement in a cascaded piezoelectric cantilever formed in a meandering shape. The new actuator design was adopted in a double-gimbal two-dimensional optical scanner of a 4 mm times 6 mm foot print. The scanner delivered a relatively large static angle of mechanical plusmn8.6deg at an applied voltage of 20 Vdc at a non-resonant operation.
在本文中,我们提出了一种新的压电单晶片驱动器的机械设计,该驱动器通过在弯曲形状的级联压电悬臂梁中积累角位移来产生大的静态偏转角。在4 mm × 6 mm脚印的双框架二维光学扫描仪中采用了新的致动器设计。在非谐振操作下,当施加电压为20vdc时,扫描仪提供了相对较大的静态机械角度8.6度。
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引用次数: 54
Environment friendly MEMS fabrication: Proposal of new D-RIE process gases for reduction of green house effect 环境友好型MEMS制造:提出新的D-RIE工艺气体以减少温室效应
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433105
S. Nagano, T. Shibata, K. Sakoda, M. Inoue, S. Hasaka, T. Takano, T. Ikehara, R. Maeda
Environmental emission volume of green house gases such as SF6 and C4F8, consumed for Si deep etching process in MEMS fabrication, are increasing followed by the MEMS market growth. To reduce the emitted green house gases, alternative C3F6 and IF5 were investigated to be applied for MEMS etching process instead of conventional Bosch process gases. The C3F6 and IF5 gases have very small global warming potential, so that they were useful to reduce over 95% of the green house gases maintaining the good etching performance on both etching rate and etching profile. The reduction of warming gas emission by the new gases is estimated that approximately 43 trees might be conserved during one etching process of a wafer to 300 mum. In addition to this merit, IF5 is found to be applied for anisotropic trench etching without Bosch process.
随着MEMS市场的增长,MEMS制造过程中硅深刻蚀过程所消耗的SF6和C4F8等温室气体的环境排放量也在增加。为了减少温室气体的排放,研究了C3F6和IF5替代传统博世工艺气体用于MEMS蚀刻工艺。C3F6和IF5气体具有非常小的全球变暖潜势,因此它们有助于减少95%以上的温室气体,在蚀刻速率和蚀刻剖面上保持良好的蚀刻性能。据估计,在晶圆片的一次蚀刻过程中,新气体减少了大约43棵树的温室气体排放,达到300棵树。除此之外,IF5还可以应用于非博世工艺的各向异性沟槽刻蚀。
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引用次数: 1
Mechanical characterization of silicon nitride thin-films using microtensile specimens with integrated 2D diffraction gratings 利用集成二维衍射光栅的微拉伸试样对氮化硅薄膜进行力学表征
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4432964
J. Gaspar, Y. Nurcahyo, P. Ruther, O. Paul
This paper reports on the mechanical characterization of microtensile specimens made of silicon nitride (SiNx) thin-films with integrated 2D reflective gratings. By applying an axial force, the structures respond mechanically with an elongation and contraction in the longitudinal and transversal directions, respectively. The corresponding variations of both periods of the grating are monitored in real time by measuring the diffraction pattern resulting from the illumination of the grating with monochromatic light. The strain components are thus evaluated locally in the structure. By integrating such an optical technique with an efficient test structure previously developed, the extraction of materials' Young's modulus E, Poisson's ratio nu, residual strain epsivres and stress sigmares and fracture strength sigma0 is in principle made possible from the measurement of a single test structure. Here we demonstrate the extraction of E, epsivres, sigmares and sigma0 of the nitride films.
本文报道了集成二维反射光栅的氮化硅(SiNx)薄膜微拉伸试样的力学特性。通过施加轴向力,结构在纵向和横向上分别产生伸长和收缩的机械反应。通过测量单色光照射光栅产生的衍射图,实时监测光栅两个周期的相应变化。因此,应变分量在结构中被局部评估。通过将这种光学技术与先前开发的高效测试结构相结合,原则上可以从单个测试结构的测量中提取材料的杨氏模量E、泊松比nu、残余应变系数和应力信号以及断裂强度sigma0。在这里,我们演示了氮化膜的E, epsivres,信号和sigma0的提取。
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引用次数: 8
Rapid synthesis of carbon nanotubes by bulk and localized inductive heating 本体和局部感应加热快速合成碳纳米管
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433096
B. D. Sosnowchik, Liwei Lin
In this work, we report a rapid yet simple methodology for the synthesis of carbon nanotubes (CNTs) in a room temperature environment using an inductive heating system with either a) bulk synthesis on silicon chips, or b) local synthesis on suspended MEMS structures. This setup enables growth and integration of CNTs with MEMS structures in a matter of 1-2 minutes. For bulk synthesis, high growth rates of up to 200 mum/min were obtained, resulting in growth of vertically aligned CNTs with an average diameter of 6.8nm. Integration from bulk- grown CNTs on MEMS structures resulted in lower resistances from larger diameter CNTs. Localized synthesis and integration was also obtained on suspended copper microstructures, illustrating an ohmic CNT response with a resistance of 110 kOmega. The breadth of synthesis and integration capabilities enabled by inductive heating illustrates a new class of rapid synthesis for vapor-liquid-solid-grown nanostructures.
在这项工作中,我们报告了一种在室温环境下使用感应加热系统快速而简单地合成碳纳米管(CNTs)的方法,其中a)硅片上的整体合成或b)悬浮MEMS结构上的局部合成。这种设置可以在1-2分钟内实现碳纳米管与MEMS结构的生长和集成。对于体合成,获得了高达200 mum/min的高生长速率,从而生长出平均直径为6.8nm的垂直排列的碳纳米管。大块生长的碳纳米管在MEMS结构上的集成导致更大直径碳纳米管的电阻更低。在悬浮铜微结构上也获得了局部合成和集成,说明了电阻为110 kOmega的欧姆碳纳米管响应。通过感应加热实现的合成和集成能力的广度说明了一种新型的蒸汽-液体-固体生长纳米结构的快速合成。
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引用次数: 7
Carbon nanotube-based strain sensing cantilevers 碳纳米管应变传感悬臂梁
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433135
J. Tong, M. Priebe, Yu Sun
This paper presents the design, fabrication, and testing results of silicon cantilevers with carbon nanotubes (CNTs) as active strain sensing elements. A batch microfabrication process was developed for device construction and packaging. Multi-walled carbon nanotubes (MWNTs) were dielectrophoretically assembled between electrodes. Based on the characterization results of 12 devices, the CNT-based cantilevers demonstrated a linear relationship between resistance changes and externally applied strain. The gauge factor ranged from 78.84 to 134.40 for four different microelectrode configurations.
本文介绍了以碳纳米管作为主动应变传感元件的硅悬臂梁的设计、制造和测试结果。开发了一种用于器件构造和封装的批量微加工工艺。多壁碳纳米管(MWNTs)在电极间介电泳组装。基于12个器件的表征结果,基于碳纳米管的悬臂梁在电阻变化和外部施加应变之间表现出线性关系。对于四种不同的微电极配置,测量因子范围为78.84 ~ 134.40。
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引用次数: 3
Design and fabrication of an artificial skin using PI-copper films 使用pi -铜薄膜的人造皮肤的设计与制造
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433149
Ming-Yuan Cheng, W.-Y. Chang, L. Tsao, S.-A. Yang, Y. Yang, W. Shih, F. Chang, S. Chang, K. Fan
This paper presents the design, fabrication and measurement of a flexible 8 times 8 temperature and tactile sensing array which will be used as the artificial skin for robot applications. The temperature and pressure sensing elements are heterogeneously integrated on a flexible copper-PI film using micromachining techniques. The tactile sensing elements are fabricated by dispensing conductive polymer on the pre-defined inter-digital copper electrodes. Discrete temperature sensor chips are employed as the temperature sensing elements. Scanning circuits are implemented and experimental results are also provided.
本文介绍了一种柔性的8 × 8温度和触觉传感阵列的设计、制造和测量,该阵列将用作机器人的人造皮肤。采用微加工技术将温度和压力传感元件异质集成在柔性铜- pi薄膜上。触觉传感元件是通过在预先定义的数字间铜电极上分配导电聚合物来制造的。采用离散式温度传感器芯片作为温度传感元件。实现了扫描电路,并给出了实验结果。
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引用次数: 23
Small, soft, and safe microactuator for retinal pigment epithelium transplantation 小、软、安全的视网膜色素上皮移植微致动器
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433083
Yusaku Watanabe, Masanori Maeda, N. Yaji, R. Nakamura, H. Iseki, M. Yamato, T. Okano, Sadao Hori, Satoshi Konishi
This paper proposes a novel surgical tool for the retinal pigment epithelium (RPE) sheet transplantation. The proposed tool employs the principle of pneumatic balloon actuator (PBA). It is possible to design small, soft and safe surgical tool by using PBA because PBA is made of PDMS and driven by pneumatic pressure. These distinctive characteristics of PBA are attractive for such a challenging surgery as the RPE sheet transplantation in an eyeball. The designed head size of tool is 3 mm times 3 mm times 100 mum by taking account of the size of the RPE sheet (3 mm times 3 mm). The developed tool can perform sequential motions through independent control of different PBA so as to introduce and transplant the RPE sheet to an eyeball. Generated force by the movement of the transplantation tool is measured around 3 mN, which is allowable in an eyeball. Experimental results of both in vitro and in vivo test by using the developed tool will be reported to demonstrate feasibility of our strategy.
本文提出一种新的视网膜色素上皮(RPE)片移植手术工具。该工具采用气动球囊执行器(PBA)的工作原理。由于PBA由PDMS制成,由气压驱动,因此PBA可以设计出小巧、柔软、安全的手术工具。PBA的这些独特特征对于眼球内RPE片移植这样具有挑战性的手术是有吸引力的。考虑到RPE板材的尺寸(3mm × 3mm),设计的刀具头尺寸为3mm × 3mm × 100 mm。所开发的工具可以通过独立控制不同的PBA进行顺序运动,从而将RPE片引入眼球并移植到眼球上。移植工具运动产生的力约为3mn,这在眼球中是允许的。将报告使用开发的工具进行体外和体内测试的实验结果,以证明我们的策略的可行性。
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引用次数: 48
Highly efficient in-droplet particle concentration and separation by twDEP and EWOD for digital microfluidics 数字微流控的twDEP和EWOD高效滴内颗粒浓度和分离
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433153
Yuejun Zhao, U. Yi, S. Cho
This paper describes highly efficient in-droplet particle concentrations/separations (over 92% efficiency), where target particles are concentrated/separated within a droplet by traveling wave dielectrophoresis (twDEP) and a subsequent EWOD (electrowetting-on-dielectric) actuation physically splits target-rich regions into individual droplets. This in-droplet method will provide a new functionality of separation/concentration for digital (droplet-based) microfluidics [1], thereby possibly eliminating the necessity of adopting the conventional continuous-flow-based separation methods.
本文描述了高效的液滴颗粒浓缩/分离(效率超过92%),其中目标颗粒通过行波介质电泳(twDEP)在液滴内浓缩/分离,随后的EWOD(介电电润湿)驱动将富含目标的区域物理地分割成单个液滴。这种液滴内方法将为数字(基于液滴的)微流体提供一种新的分离/浓缩功能[1],从而可能消除采用传统的基于连续流的分离方法的必要性。
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引用次数: 12
Deep wet etching-through 1mm pyrex glass wafer for microfluidic applications 深湿蚀刻通过1mm耐热玻璃晶圆微流体应用
Pub Date : 2007-01-01 DOI: 10.1109/MEMSYS.2007.4433150
C. Iliescu, Bangtao Chen, J. Miao
This paper addresses the main issues related to wet micromachining of one of the mostly used BioMEMS materials - glass - and proposes two optimized solutions for deep wet etching. As a result, 500 mum-thick Pyrex glass wafer was etched using an etching mask consisting of low stress amorphous silicon (a: Si) and photoresist. Moreover we report the successful through etching of 1 mm Pyrex glass wafer using a combination of low stress a: Si/SiC/photoresist mask.
本文讨论了与湿法微加工有关的主要问题,并提出了两种深度湿法蚀刻的优化解决方案。利用低应力非晶硅(a: Si)和光刻胶组成的蚀刻掩膜蚀刻了500 mm厚的耐热玻璃晶圆片。此外,我们还报道了使用低应力a: Si/SiC/光刻胶掩膜组合成功蚀刻1mm Pyrex玻璃晶圆。
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引用次数: 22
期刊
2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)
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