Bulletin Du Cancer最新文献

{"title":"Représentativité des patients atteints de cancer du poumon : différences entre un registre de cancer populationnel et un centre hospitalier universitaire","authors":"Alexandre Quillet , Nicolas Isambert , Thomas Systchenko , Nolwenn Le Stang , Gautier Defossez","doi":"10.1016/j.bulcan.2025.03.012","DOIUrl":"10.1016/j.bulcan.2025.03.012","url":null,"abstract":"","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1061-1064"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Évolution du parcours patient d’oncologie : motifs d’évacuation sanitaire après plus de 2000 discussions de dossiers en RCP Pacifique","authors":"Charles Honoré , Nicolas Epaillard , Arthur Geraud , Ronan Flippot , Gabriel C.T.E. Garcia , Margarida Matias , Felix Blanc-Durand , Chayma Bousrih , Jean Zeghondy , Robert Hervé , Laury Cherot , Pierre Gustin , Gianmaria Drovetti , Michel Ducreux","doi":"10.1016/j.bulcan.2025.02.023","DOIUrl":"10.1016/j.bulcan.2025.02.023","url":null,"abstract":"<div><h3>Introduction</h3><div>L’inégalité d’accès aux soins innovants et spécialisés dans les territoires d’Outre-mer, entraîne une perte de chance pour les patients atteints de cancers. Depuis 2019, une réunion de concertation pluridisciplinaire (RCP) en visioconférence entre Polynésie française, Nouvelle-Calédonie, et France hexagonale dénommée RCP Pacifique, facilite l’accès à l’expertise médicale et limite le recours aux évacuations sanitaires (EVASAN).</div></div><div><h3>Méthodes</h3><div>Nous avons analysé rétrospectivement tous les dossiers discutés en RCP Pacifique entre 2019 et 2024 pour rapporter les motifs d’EVASAN et évolutions post-EVASAN.</div></div><div><h3>Résultats</h3><div>Sur les 2010 discussions de dossiers concernant 1159 patients, 242 décisions d’EVASAN ont été prises (12 % des discussions ; 20,9 % des patients) pour 119 patients de Polynésie française (49,2 %) et 123 de Nouvelle-Calédonie (50,8 %). Les principaux motifs d’EVASAN décidés en RCP Pacifique étaient : chirurgie (48,3 %), geste de radiologie interventionnelle (14,0 %), radiothérapie complexe (14,0 %) et TEP-scanner (12,4 %). Malgré une EVASAN recommandée, 30 patients n’ont pas été évacués pour les motifs suivants : prise en charge dans un centre australien, urgence nécessitant un traitement à domicile, résolution du problème <em>via</em> une téléconsultation, confinement Covid, refus du patient. Après EVASAN, 82,6 % des patients sont rentrés à domicile après traitement.</div></div><div><h3>Conclusions</h3><div>Les RCP Pacifique offrent une solution pour limiter le recours aux EVASAN dans les territoires d’Outre-mer, tout en garantissant l’équité d’accès aux soins. Le renforcement des infrastructures locales et un transfert accru de compétences techniques sont les clefs pour développer cet objectif.</div></div><div><h3>Introduction</h3><div>Disparities in care between the French mainland and overseas territories are responsible for unequal access to innovative and specialized care, leading to an increased death risk for cancer patients. Since 2019, a multidisciplinary consultation meeting (<em>RCP Pacifique</em>) by videoconference between French Polynesia (Pf), New Caledonia (NC) and mainland France, facilitates access to medical expertise and limits the use of medical evacuations (EVASAN).</div></div><div><h3>Methods</h3><div>We retrospectively analyzed all files discussed in the <em>RCP Pacifique</em> between 2019 and 2024 to report demographic data, reasons for EVASAN and post-EVASAN developments.</div></div><div><h3>Results</h3><div>Of the 2010 discussions concerning 1159 patients, 242 EVASAN decisions were made (12% of discussions; 20.9% of patients) for 119 Pf patients (49.2%) and 123 NC patients (50.8%). The main reasons for EVASAN decided were: surgery (48.3%), interventional radiology procedure (14.0%), complex radiotherapy (14.0%) and PET-scan (12.4%). Despite a recommended EVASAN, 30 patients were not evacuated for the following reasons: treatment in","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 988-995"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Éclectisme et diversité, le numéro d’un monde idéal","authors":"Jacques-Olivier Bay , Stéphane Vignot , Philippe Pourquier , Nathalie Mazure","doi":"10.1016/j.bulcan.2025.08.002","DOIUrl":"10.1016/j.bulcan.2025.08.002","url":null,"abstract":"","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 923-924"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Propositions pour développer l’innovation et la recherche en cancérologie et optimiser les prises en soin des patients touchés par le cancer","authors":"Estelle Dhamelincourt ,&nbsp;Guillaume Bezie ,&nbsp;Hamza Bissaoui ,&nbsp;Thomas Bonnotte ,&nbsp;Olivier Carduner ,&nbsp;François-Guirec Champoiseau ,&nbsp;Claude Coutier ,&nbsp;Martin Duval ,&nbsp;Virginie Femery ,&nbsp;Charles Ferté ,&nbsp;Thierry Guillaume ,&nbsp;Nelly Jennin ,&nbsp;Abdessamia Gandoul ,&nbsp;Alexandre Iat ,&nbsp;Nicolas Martelin ,&nbsp;Emeline Mas ,&nbsp;Carole Micheneau ,&nbsp;Sébastien Mourey ,&nbsp;Bénédicte Piron ,&nbsp;Charles Raynaud ,&nbsp;Michel Le Taillanter","doi":"10.1016/j.bulcan.2025.06.004","DOIUrl":"10.1016/j.bulcan.2025.06.004","url":null,"abstract":"<div><div>Les patients atteints de cancer font face à un parcours de soins complexe, avec des défis liés à l’intégration des innovations thérapeutiques, technologiques et numériques. En 2025, la lutte contre le cancer nécessite une approche multidimensionnelle, alliant traitements avancés et prise en compte des besoins individuels des patients. Lors des Rencontres de la cancérologie française 2024, divers acteurs, dont des associations de patients, des entreprises et des <em>startups</em>, des établissements de santé et des associations professionnelles, ont débattu avec les experts en cancérologie de l’intégration des données patients dans la recherche. Neuf propositions consensuelles ont été formulées pour améliorer cette intégration.</div></div><div><div>Cancer patients face a complex care pathway, with challenges related to the integration of therapeutic and digital innovations. In 2025, the fight against cancer requires a multifaceted approach, combining advanced treatments and consideration of individual patient needs. At the November 2024 RCFr, various stakeholders, including patient associations, companies and startups, healthcare institutions, and professional associations, discussed with cancer experts the integration of patient data into cancer research. Nine consensus proposals were formulated to improve this integration.</div></div>","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1065-1073"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"À la recherche (scientifique) des facteurs de risques connus","authors":"Pierre Sujobert ,&nbsp;Marc Billaud","doi":"10.1016/j.bulcan.2025.06.002","DOIUrl":"10.1016/j.bulcan.2025.06.002","url":null,"abstract":"","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1056-1057"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repotrectinib pour les carcinomes bronchiques non à petites cellules avec fusions de ROS1, pré-traités par crizotinib","authors":"Clara Vacheret ,&nbsp;Mihaela Aldea","doi":"10.1016/j.bulcan.2025.03.011","DOIUrl":"10.1016/j.bulcan.2025.03.011","url":null,"abstract":"","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 929-931"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic factors of breast cancer and survival in Sub-Saharan Africa: A systematic review and meta-analysis","authors":"Alexis Parenté ,&nbsp;Freddy Houéhanou Rodrigue Gnangnon ,&nbsp;David Kinsou ,&nbsp;Mohamad Chkeir ,&nbsp;Caroline Adou ,&nbsp;Hélène Robin Sacca ,&nbsp;Mahiné Ivanga ,&nbsp;Edgard Ngoungou ,&nbsp;Tchin Paolo Darré ,&nbsp;Dismand Houinato ,&nbsp;Pierre-Marie Preux ,&nbsp;Véronique Blanquet","doi":"10.1016/j.bulcan.2025.05.009","DOIUrl":"10.1016/j.bulcan.2025.05.009","url":null,"abstract":"<div><h3>Background</h3><div>Breast cancer is an escalating public health concern in Sub-Saharan Africa (SSA), where mortality rates remain disproportionately high despite lower incidence compared to Western countries. The combination of late-stage diagnoses, limited healthcare infrastructure, and socioeconomic inequalities severely compromises patient outcomes.</div></div><div><h3>Methods</h3><div>We conducted a systematic review and meta-analysis of 85 studies encompassing 33,053 patients across SSA to characterize breast cancer profiles, focusing on age at diagnosis, cancer stage, molecular subtypes, and survival outcomes.</div></div><div><h3>Findings</h3><div>The mean age at diagnosis was 48.7 years, notably younger than in high-income regions. Half of the patients were diagnosed at stage III, and only 4% at stage I. Luminal A was the most prevalent molecular subtype (30%), followed closely by triple-negative breast cancer (29%), known for its aggressive course and limited treatment options. Survival analysis revealed a pooled 5-year survival rate of 44%, with substantial regional disparities: survival was poorest in West Africa and comparatively better in East Africa and South Africa.</div></div><div><h3>Conclusions</h3><div>Our findings expose the critical need for regionally tailored interventions to improve early detection, expand access to comprehensive treatment, and address underlying social determinants of health. This study delivers essential epidemiological benchmarks that should inform targeted strategies for reducing the breast cancer burden and improving survival across Sub-Saharan Africa.</div></div>","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1024-1034"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144565555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Réflexions sur la cancérologie dans les territoires ultramarins","authors":"Jean-Pierre Droz","doi":"10.1016/j.bulcan.2025.05.010","DOIUrl":"10.1016/j.bulcan.2025.05.010","url":null,"abstract":"","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 939-945"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"La prise en charge infirmière des plaies tumorales","authors":"Isabelle Fromantin ,&nbsp;Elodie Labedade ,&nbsp;Charlotte Van Coppenolle","doi":"10.1016/j.bulcan.2025.01.008","DOIUrl":"10.1016/j.bulcan.2025.01.008","url":null,"abstract":"<div><div>Les plaies tumorales touchent 5 à 10 % des patients atteints de cancer métastatique. La gestion des symptômes (hémorragie, odeurs, exsudats, douleurs) liés à la présence de ces lésions est parfois complexe et requiert une approche multidisciplinaire, où chacun agit en complémentarité. Des solutions locales peuvent être proposées pour chaque symptôme local. L’infirmier doit s’efforcer d’élaborer pour chaque patient un protocole de soins toujours au plus simple et permettant une continuité ville–hôpital. Les protocoles de soins doivent être fréquemment réajustés en fonction des fluctuations de la plaie. La prise en charge infirmière ne se limite pas au soin de la plaie, elle inclut la surveillance des risques et de l’état général du patient, notamment l’état nutritionnel et des conséquences fonctionnelles et psychiques liées à la présence de la plaie.</div></div><div><div>Malignant wounds affect 5 to 10% of patients with metastatic cancer. The management of symptoms (hemorrhage, odors, exudates, pain) linked to the presence of these lesions is sometimes complex and requires a multidisciplinary approach, where everyone acts in complementarity. Local solutions can be proposed for each local symptom. The nurse must strive to develop for each patient a wound care protocol that is always as simple as possible and allows for home care-hospital continuity. Care protocols must be frequently readjusted based on wound fluctuations. Nursing care is not limited to wound care, it includes monitoring the risks and the global condition of the patient, in particular the nutritional state and the functional and psychological consequences linked to the presence of the malignant wound.</div></div>","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1045-1050"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traitement néoadjuvant par imatinib des tumeurs stromales gastro-intestinales localement avancées : théorie et pratique","authors":"Nicolas Penel ,&nbsp;Antoine Cayeux ,&nbsp;Gauthier Decanter ,&nbsp;Loïc Lebellec","doi":"10.1016/j.bulcan.2025.04.011","DOIUrl":"10.1016/j.bulcan.2025.04.011","url":null,"abstract":"<div><div>Dans cette revue, nous faisons le point sur les essais cliniques publiés évaluant un traitement néoadjuvant par imatinib pour tumeurs stromales gastro-intestinales localement avancées. Nous illustrons la pratique au travers une vignette clinique, permettant de souligner des suggestions pratiques.</div></div><div><div>In this review we summarised published clinical trials evaluating neoadjuvant treatment with imatinib for locally advanced gastro-intestinal stromal tumours. We illustrate the practice through a clinical vignette, allowing us to highlight practical suggestions.</div></div>","PeriodicalId":9365,"journal":{"name":"Bulletin Du Cancer","volume":"112 9","pages":"Pages 1051-1055"},"PeriodicalIF":0.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}