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2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20-24 January 2013. IEEE International Conference on Micro Electro Mechanical Systems (26th : 2013 : Taipei, Taiwan)最新文献

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Intra/extracellular investigation for ion channels with lipid bilayer array at the single molecule level 单分子水平脂质双分子层阵列离子通道的细胞内/细胞外研究
R. Kawano, Y. Tsuji, M. Hirano, T. Osaki, K. Kamiya, N. Miki, T. Ide, S. Takeuchi
This paper describes an investigation of drug effects for ion channels with recognizing the intra/extracellular directions. We have previously reported the ion channel recordings with bilayer lipid membranes (BLMs) which formed on a parylene micropore using droplets contact method. However, the low reconstitution probability of ion channels into BLMs has been a major issue. In this study, BLMs area and position are regulated with changing the numbers and positions of the parylene micropores. As a result, the simultaneous single channel recordings of K+ channel expressed in nerve system with BLM array were able to be achieved at the high probability.
本文介绍了药物对细胞内/细胞外离子通道作用的研究。我们以前报道过用液滴接触法在聚对二甲苯微孔上形成的双层脂质膜(BLMs)上记录离子通道。然而,离子通道进入blm的重构概率低一直是一个主要问题。在本研究中,BLMs的面积和位置随聚对二甲苯微孔数量和位置的变化而变化。因此,用BLM阵列可以高概率地同时记录神经系统中表达的K+通道。
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引用次数: 0
Development of MWCNT embedded micromechanical resonator working as rarefied gas sensor 作为稀薄气体传感器的MWCNT嵌入式微机械谐振器的研制
H. Kishihara, I. Hanasaki, N. Matsuzuka, I. Yamashita, Y. Uraoka, Y. Isono
This research has newly developed the multi-wall carbon nanotubes (MWCNTs) embedded-micro-mechanical resonator working as a novel rarefied gas sensor. The inertial effect of rarefied gas fluid is detected as a variation of the resonance frequency, and the dissipation of the interaction energy between the resonator and the gas molecules affects the damping of oscillation. Thus, two kinds of gaseous species can be distinguished with one device. The MWCNTs have been arranged on the resonator for heightening its sensitivity by the bio-MEMS compatible process. The MWCNTs embedded-resonator has successfully demonstrated to detect and distinguish hydrogen and nitrogen gases under pressures of 0.02 Pa to 0.9 Pa.
本研究开发了多壁碳纳米管嵌入式微机械谐振器,作为一种新型的稀薄气体传感器。稀薄气体流体的惯性效应表现为谐振频率的变化,谐振腔与气体分子之间相互作用能量的耗散影响振荡的阻尼。因此,可以用一个装置来区分两种气体。为了提高谐振器的灵敏度,采用生物mems兼容工艺,在谐振器上放置了MWCNTs。MWCNTs嵌入谐振器已成功证明可以在0.02 Pa至0.9 Pa的压力下检测和区分氢气和氮气。
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引用次数: 0
Crystallographic and eigenmode dependence of TCf for single crystal silicon contour mode resonators 单晶硅轮廓模谐振器中TCf的晶体学和特征模依赖性
H. Zhu, G. Shan, Cheng Tu, Joshua E-Y Lee
This paper reports the effects of crystal orientations on the temperature coefficient of frequency (TCf) of single crystal silicon square-plate micromechanical resonators vibrating in two distinct contour modes: Lamé mode and square extensional (SE). For the Lamé mode, the same TCf was found over several devices aligned to the <;110> direction, while much greater variation in the TCf was observed among the devices aligned against the <;100> direction. For the SE mode, the devices in both <;100> and <;110> orientations exhibit similar TCf values for varying doping levels. These observations are supported by Keyes' theory and close agreement between experiments and simulations is shown.
本文报道了晶体取向对单晶硅方形微机械谐振器在两种不同的轮廓模式下振动的频率温度系数(TCf)的影响:lam模式和方形伸展模式。对于lam模式,在几个与方向对齐的器件中发现了相同的TCf,而在与方向对齐的器件中观察到更大的TCf变化。对于SE模式,在不同掺杂水平下,两个方向的器件表现出相似的TCf值。这些观察得到了Keyes理论的支持,实验和模拟之间的密切一致。
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引用次数: 5
Methods for the microfabrication of magnesium 镁的微加工方法
M. Tsang, F. Herrault, R. Shafer, M. Allen
The mechanical and electrochemical properties of magnesium are favorable for biomedical and energy storage applications. However, magnesium microfabrication has been limited to sub-micron-thick film technologies (i.e., sputtering or evaporation). This paper presents three magnesium microfabrication approaches for thicknesses greater than 10 μm: 1) laser-cutting and 2) chemical etching of 70-μm-thick commercial magnesium foil; and 3) through-mold electroplating of magnesium from non-aqueous solution. The fabrication technologies are compared on minimum feature size, morphology, uniformity, composition and electrical resistivity. Preliminary results confirmed that the 50-μm-thick electroplated material composition compared favorably with commercial magnesium foil. The measured electrical resistivities of commercial and electrodeposited magnesium were 5.3 μΩ·cm and 8.7 μΩ·cm, respectively. Thick magnesium microstructures can be fabricated through several means to serve a broad range of MEMS-based applications.
镁的力学和电化学性能有利于生物医学和储能应用。然而,镁的微加工仅限于亚微米厚的薄膜技术(即溅射或蒸发)。提出了厚度大于10 μm的三种镁微细加工方法:70 μm厚商用镁箔的激光切割和化学刻蚀;3)非水溶液镁的透模电镀。从最小特征尺寸、形貌、均匀性、成分和电阻率等方面对制备工艺进行了比较。初步结果证实,所制备的50 μm厚的电镀材料组成优于市售镁箔。测得商品镁和电沉积镁的电阻率分别为5.3 μΩ·cm和8.7 μΩ·cm。厚镁微结构可以通过几种方法制造,以服务于广泛的基于mems的应用。
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引用次数: 7
A microfluidic droplet platform for multiplexed single nucleotide polymorphism analysis of an array plant genomic DNA samples 阵列植物基因组DNA样品多路单核苷酸多态性分析的微流控液滴平台
H. Zec, T. Rane, Dr. Wen-Chy Chu, Vivian Wang, Dr. Tza-Huei Wang
A programmable droplet-based platform which performs multiplexed single nucleotide polymorphism analysis on an array of plant genomic DNA samples is presented. This device has the potential to meet the demand for flexible and cost-effective tools that can perform high throughput genetic screening for applications such as allelic variation detection in agriculture. The microfluidic droplet-based device accepts an unlimited number of sample plugs containing genomic plant DNA from a multi-well plate. Each plug is separated by a fluorinated immiscible carrier fluid to prevent cross-contamination. Once plugs are loaded on to the device, mechanical chopping of these sample plugs is performed to digitize them into smaller daughter droplets. The device then performs subsequent synchronization-free, robust injection of multiple single nucleotide polymorphism interrogating probes in to the sample daughter droplets on-demand. This microfluidic platform combines the excellent control of valve-based microfluidics with the high-throughput capability of droplet microfluidics. Furthermore, generation of a one-dimensional array of combinatorial mixtures of DNA-probe droplets in which the sequence of drops is maintained throughout the device leads to automatic spatial indexing of these droplets, precluding the need for barcoding to identify droplet contents. We expect this flexible platform to expand the range of applications of droplet microfluidics to include applications requiring high degrees of multiplexing as well as high throughput screening of arrays of samples.
提出了一种基于可编程液滴的植物基因组DNA多路单核苷酸多态性分析平台。该设备有潜力满足对灵活和具有成本效益的工具的需求,这些工具可以执行高通量遗传筛选,如农业中的等位基因变异检测。基于微流控液滴的装置接受来自多孔板的含有基因组植物DNA的无限数量的样品塞。每个塞由含氟的不混溶载体液分离,以防止交叉污染。一旦插头被加载到设备上,就会对这些样品插头进行机械切割,将它们数字化成更小的子液滴。然后,该设备执行随后的无同步,按需将多个单核苷酸多态性询问探针注入样品子液滴中。该微流控平台结合了基于阀的微流控的卓越控制和液滴微流控的高通量能力。此外,在整个装置中保持液滴序列的dna探针液滴组合混合物的一维阵列的产生导致这些液滴的自动空间索引,排除了识别液滴内容的条形码的需要。我们希望这个灵活的平台能够扩大液滴微流体的应用范围,包括需要高度多路复用的应用以及样品阵列的高通量筛选。
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引用次数: 1
Wafer-to-wafer selective flip-chip transfer by sticky silicone bonding and laser debonding for rapid and easy integration test 通过硅树脂粘接和激光脱粘的晶圆到晶圆选择性倒装转移,实现快速简便的集成测试
S. Tanaka, M. Yoshida, H. Hirano, T. Somekawa, M. Fujita, M. Esashi
Wafer-bonding-based integration can be rapidly and easily tested between different types of devices by wafer-to-wafer flip-chip transfer technology described in this paper. Devices to be tested (e.g. MEMS) on a support wafer are bonded and electrically connected with a target wafer (e.g. LSI) using sticky silicone bumps, and then any of the devices are selectively debonded from the support wafer by backside laser irradiation. After transferred, the device is temporary sealed with a silicone ring, and underfill polymer can be used for permanent bonding. Because silicone bonding is made just by physical contact at room temperature, and the elasticity of silicone absorbs mismatch in thermal expansion, integration between different materials of wafer is possible. For practical demonstration, LiNbO3-based SAW resonators were transferred to an LSI wafer.
基于晶圆键合的集成可以通过本文描述的晶圆到晶圆倒装芯片传输技术在不同类型的器件之间快速方便地进行测试。在支撑晶圆上被测试的器件(如MEMS)使用粘性硅块与目标晶圆(如LSI)粘合并电连接,然后通过背面激光照射选择性地将任何器件从支撑晶圆上剥离。设备转移后用硅胶环临时密封,下填充聚合物可进行永久粘接。由于硅酮在室温下仅通过物理接触形成键合,并且硅酮的弹性吸收了热膨胀时的失配,使得硅片不同材料之间的集成成为可能。为了实际演示,将基于linbo3的SAW谐振器转移到LSI晶圆上。
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引用次数: 9
High-Q fused silica birdbath and hemispherical 3-D resonators made by blow torch molding 高q熔融硅水盆及吹炬成型半球形三维谐振器
J. Cho, Jialiang Yan, J. A. Gregory, H. Eberhart, R. L. Peterson, K. Najafi
This paper presents a novel 3-D fabrication process of microstructures using high-Q materials. The key feature of this process is the use of a blow torch that can provide intensive localized heat up to 2500°C in a very short time (<;10 sec), above the melting temperatures of many high-Q materials such as fused silica. Surface roughness of 5.3 Å is realized in fused silica, which is crucial for high optical and mechanical quality factors (Q). We demonstrate the fabrication of micro hemisphere and half-toroid (birdbath) geometries from 100μm-thick fused silica substrates. We also create micro birdbath resonators by batch-level releasing the birdbath shells and demonstrate one of the best mechanical Q and low stiffness and damping anisotropies among existing micro mechanical resonators. The birdbath resonator is promising for emerging applications such as micro rate-integrating gyroscope (μ-RIG).
本文提出了一种利用高q材料制备微结构的三维新工艺。该工艺的主要特点是使用吹炬,可以在很短的时间内(< 10秒)提供高达2500°C的密集局部加热,高于许多高q材料(如熔融二氧化硅)的熔化温度。在熔融二氧化硅中实现了5.3 Å的表面粗糙度,这对于高光学和机械质量因子(Q)至关重要。我们展示了在100μm厚的熔融二氧化硅衬底上制造微半球和半圆环(水盆)几何形状。我们还通过批量释放水浴壳的方法创建了微水浴谐振器,并展示了现有微机械谐振器中最好的机械Q和低刚度和阻尼各向异性之一。水浴谐振器在微速率积分陀螺仪(μ-RIG)等新兴应用中前景广阔。
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引用次数: 50
Horizontal lipid bilayers formed by droplets contact method on patterned micro-droplets 用液滴接触法在图案微液滴上形成水平脂质双分子层
T. Tonooka, K. Sato, R. Kawano, T. Osaki, S. Takeuchi
We developed horizontal lipid bilayers by the Droplets Contact Method (DCM). DCM is the easiest and most efficient method to form lipid bilayers. However, the lipid bilayers formed by our previous method could not be used for simultaneous electrophysiological and optical measurements because the bilayers are vertically oriented and therefore optically invisible. We performed DCM on patterned micro-droplets, so that the horizontal lipid bilayers were obtained. We visualized the lipid bilayer formation by an optical microscope and detected the current signals of the pore-forming membrane protein, α-hemolysin.
采用液滴接触法(DCM)制备水平脂质双分子层。DCM是形成脂质双分子层最简单、最有效的方法。然而,我们以前的方法形成的脂质双分子层不能同时用于电生理和光学测量,因为双分子层是垂直取向的,因此光学上是不可见的。我们对图案微滴进行DCM,从而获得水平脂质双分子层。利用光学显微镜观察脂质双分子层的形成过程,并检测成孔膜蛋白α-溶血素的电流信号。
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引用次数: 0
Linear actuation piezoelectric microcantilever using tetragonal composition PZT thin films 线性驱动压电微悬臂梁的四方组成PZT薄膜
T. Kobayashi, N. Makimoto, T. Oikawa, A. Wada, H. Funakubo, R. Maeda
We have fabricated piezoelectric microcantilevers using tetragonal composition Pb(Zr0.3, Ti0.7)O3 (tetra-PZT) thin films and characterized their displacement-voltage behavior under AC actuation condition. The remnant polarization, coercive voltage and piezoelectric constant d31 of the tetra-PZT thin films have increased to 65.5 μC/Cm2, 20 V, and -42 pm/V by applying AC voltage of 80 V as "wakeup" treatment. The fabricated piezoelectric microcantilevers using tetra-PZT thin films have successfully demonstrated linear displacement-voltage behavior under AC actuation condition between -15 V to 15 V.
我们采用四边形成分Pb(Zr0.3, Ti0.7)O3 (tetrai - pzt)薄膜制备了压电微悬臂梁,并对其在交流驱动条件下的位移-电压行为进行了表征。采用交流电压80 V“唤醒”处理后,薄膜的残余极化、矫顽力电压和压电常数d31分别提高到65.5 μC/Cm2、20 V和-42 pm/V。在-15 V ~ 15 V的交流驱动条件下,采用四压电薄膜制备的压电微悬臂梁成功地表现出了线性位移-电压行为。
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引用次数: 6
Ald aluminum oxide as protective coating against oxidation of LPCVD SiC microhotplates al2o3作为LPCVD SiC微热板的氧化防护涂层
B. Morana, G. Fiorentino, G. Pandraud, J. Creemer, P. Sarro
Here we present a method to strongly reduce the oxidation of conductive polycrystalline silicon carbide (poly-SiC) layers. We employed a thin (45 nm) layer of aluminum oxide (Al2O3) as protective coating against oxidation. This layer was deposited by atomic layer deposition (ALD) to achieve a high quality and conformal coating. Microheaters made of nitrogen doped poly-SiC (poly-SiC:N) were oxidized at elevated temperatures in both wet and dry atmospheres. Electrical characterizations of the microheaters show that the proposed coating is able to reduce the oxide growth by a factor of 11 for wet oxidation at 1000 °C.
本文提出了一种有效降低导电多晶碳化硅(poly-SiC)层氧化的方法。我们采用了一层薄薄的(45纳米)氧化铝(Al2O3)作为防止氧化的保护涂层。采用原子层沉积法(ALD)沉积该涂层,获得了高质量的保形涂层。用掺氮的多晶碳化硅(poly-SiC:N)制成的微加热器在干湿气氛下进行高温氧化。微加热器的电特性表明,在1000℃的湿氧化条件下,所提出的涂层能够将氧化物的生长减少11倍。
{"title":"Ald aluminum oxide as protective coating against oxidation of LPCVD SiC microhotplates","authors":"B. Morana, G. Fiorentino, G. Pandraud, J. Creemer, P. Sarro","doi":"10.1109/MEMSYS.2013.6474284","DOIUrl":"https://doi.org/10.1109/MEMSYS.2013.6474284","url":null,"abstract":"Here we present a method to strongly reduce the oxidation of conductive polycrystalline silicon carbide (poly-SiC) layers. We employed a thin (45 nm) layer of aluminum oxide (Al2O3) as protective coating against oxidation. This layer was deposited by atomic layer deposition (ALD) to achieve a high quality and conformal coating. Microheaters made of nitrogen doped poly-SiC (poly-SiC:N) were oxidized at elevated temperatures in both wet and dry atmospheres. Electrical characterizations of the microheaters show that the proposed coating is able to reduce the oxide growth by a factor of 11 for wet oxidation at 1000 °C.","PeriodicalId":92162,"journal":{"name":"2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20-24 January 2013. IEEE International Conference on Micro Electro Mechanical Systems (26th : 2013 : Taipei, Taiwan)","volume":"1973 1","pages":"484-487"},"PeriodicalIF":0.0,"publicationDate":"2013-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90212997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS 2013) : Taipei, Taiwan, 20-24 January 2013. IEEE International Conference on Micro Electro Mechanical Systems (26th : 2013 : Taipei, Taiwan)
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