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The Cosmos and WIMPs 宇宙与WIMP
Pub Date : 2020-04-30 DOI: 10.4024/n18ho19g.ntp.16.01
G. Holt
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引用次数: 0
COVID-19 2019冠状病毒疾病
Pub Date : 2020-04-30 DOI: 10.4024/n03ra20e.ntp.16.01
J. Ramsden
Background : The impact of COVID-19 vaccination on preventing or treating long COVID is unclear. We aim to assess the impact of COVID vaccinations administered (i) before and (ii) after acute COVID-19, including vaccination after long COVID diagnosis, on the rates or symptoms of long COVID. Methods : We searched PubMed, Embase, Cochrane COVID-19 trials, and Europe PMC for preprints from 1 Jan 2020 to 16 Feb 2022. We included trials, cohort, and case control studies reporting on long COVID cases and symptoms with vaccine administration both before and after COVID-19 diagnosis as well as after long COVID diagnosis. Risk of bias was assessed using ROBINS-I. Results : We screened 356 articles and found no trials, but 6 observational studies from 3 countries (USA, UK, France) that reported on 442,601 patients. The most common long COVID symptoms studied include fatigue, cough, loss of smell, shortness of breath, loss of taste, headache, muscle ache, trouble sleeping, difficulty concentrating, worry or anxiety, and memory loss or confusion. Four studies reported data on vaccination before SARS-CoV-2 infection, of which three showed statistically significant reduction in long COVID: the odds ratio of developing long COVID with one dose of vaccine ranged between OR 0.22 to 1.03; with two doses OR 0.51 to 1; and with any dose OR 0.85 to 1.01. Three studies reported on post-infection vaccination with odds ratios between 0.38 to 0.91. The high heterogeneity between studies precluded any meaningful meta-analysis. Studies failed to adjust for potential confounders such as other protective behaviours, and missing data, thus increasing the risk of bias, and decreasing the certainty of evidence to low. Discussion : Current studies suggest that COVID-19 vaccinations may have protective and therapeutic effects on long COVID. However, more robust comparative observational studies and trials are urgently needed to clearly determine effectiveness of vaccines in prevention and treatment of long COVID.
背景:COVID-19疫苗接种对预防或治疗长期COVID的影响尚不清楚。我们的目标是评估(i)在急性COVID-19之前和(ii)之后接种COVID疫苗(包括长时间COVID诊断后接种疫苗)对长时间COVID发病率或症状的影响。方法:我们检索了PubMed、Embase、Cochrane COVID-19试验和欧洲PMC从2020年1月1日至2022年2月16日的预印本。我们纳入了试验、队列和病例对照研究,这些研究报告了COVID-19诊断前后以及COVID-19诊断后长期接种疫苗的长期病例和症状。使用ROBINS-I评估偏倚风险。结果:我们筛选了356篇文章,没有发现任何试验,但发现了来自3个国家(美国、英国、法国)的6项观察性研究,共报道了442,601例患者。所研究的最常见的长冠状病毒症状包括疲劳、咳嗽、嗅觉丧失、呼吸短促、味觉丧失、头痛、肌肉疼痛、睡眠困难、注意力难以集中、担心或焦虑、记忆力丧失或混乱。4项研究报告了SARS-CoV-2感染前的疫苗接种数据,其中3项研究显示长冠状病毒的发生率有统计学意义降低:单剂疫苗发生长冠状病毒的优势比为OR 0.22 ~ 1.03;两剂OR为0.51比1;任何剂量的OR为0.85至1.01。三项研究报告了感染后疫苗接种的优势比在0.38至0.91之间。研究之间的高度异质性妨碍了任何有意义的荟萃分析。研究未能调整潜在的混杂因素,如其他保护性行为和缺失的数据,从而增加了偏倚的风险,并将证据的确定性降低到低水平。讨论:目前的研究表明,COVID-19疫苗可能对长期COVID具有保护和治疗作用。然而,迫切需要更强有力的比较观察性研究和试验,以明确确定疫苗在预防和治疗长期COVID中的有效性。
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引用次数: 0
Estimation of parameters for a model of polycrystalline solar cells 多晶太阳能电池模型参数的估计
Pub Date : 2020-04-30 DOI: 10.4024/n17sh19a.ntp.16.01
J. Shainidze, L. Kalandadze, O. Nakashidze, N. Gomidze
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引用次数: 0
J-value assessment of how best to combatCOVID-19 如何最好地抗击新冠肺炎的J值评估
Pub Date : 2020-04-04 DOI: 10.4024/n02th20a.ntp.16.01
P. Thomas
The new coronavirus infection will continue to pose a very severe challenge to the UK and to all countries around the world for the next 12 to 18 months An epidemic model has been developed to explore the range of possible actions open to the UK and other nations to combat the virus A “business as usual” policy would lead to the epidemic being over by September 2020, but such an approach would lead to a loss of life in the UK little less than what it suffered in the Second World War Using the J-value without constraint suggests that exceptionally high spending would be justified for the three strategies that could reduce significantly the numbers of cases and deaths compared with the unmitigated epidemic However such high spending is likely to come up against the J-value GDP constraint, whereby the measure should not so decrease GDP per head that the national population loses more life as a result of the countermeasure than it gains The challenge for the UK Government (and other governments around the world) will be to manage its interventions so that the recession that is now inevitable is not significantly worse than that following the 2007–9 financial crash © 2020 Collegium Basilea
在未来12至18个月内,新型冠状病毒感染将继续对英国和世界各国构成非常严峻的挑战。已经开发了一个流行病模型,以探索英国和其他国家抗击病毒的可能行动范围。“一切照旧”政策将导致疫情在2020年9月结束,但是,这样的方法将导致英国的生命损失略低于第二次世界大战时的损失。无限制地使用J值表明,与未缓解的疫情相比,这三种策略可以显著减少病例和死亡人数,因此有理由进行异常高的支出。然而,很可能会出现如此高的支出相对于J值GDP约束,因此,该措施不应降低人均GDP,使全国人口因该措施而失去的生命多于获得的生命。英国政府(以及世界各地的其他政府)面临的挑战将是管理其干预措施,使目前不可避免的衰退不会比2007-2009年金融危机后的衰退严重得多©2020巴西Collegium Basilea
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引用次数: 8
Structure, tribological behaviour and photocatalytic activity of ARC-PVD TiO2 coatingsobtained with a modified curvilinear magnetic filter 用改进的曲线磁性过滤器获得的ARC-PVD TiO2涂层的结构、摩擦学行为和光催化活性
Pub Date : 2019-07-30 DOI: 10.4024/n06ta19a.ntp.15.02
A. Taran, I. Garkusha, V. Taran, A. Timoshenko, I. Misiruk, M. A. Sergiets, T. Skoblo, S. Romaniuk, T. Maltsev, V. Starikov, A. Baturin, A. Mamalis
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引用次数: 0
Physicochemical characterization of the inclusion compounds of eugenol andβ-caryophyllene in β-cyclodextrin 丁香酚和β-石竹烯包合物在β-环糊精中的理化性质
Pub Date : 2019-07-30 DOI: 10.4024/n01sh19a.ntp.15.02
Shilpa Sharma, Anuradha Bhagat, G. Vishwakarma, S. Mittal
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引用次数: 0
Gridlock in Global Ocean Governance: Diverging National Interests in the South China Sea 全球海洋治理的僵局:南海国家利益的分歧
Pub Date : 2019-05-26 DOI: 10.15367/PJ.V5I2.203
Wesley Nappen
With the ratification of the United Nations Convention on the Law of the Sea (UNCLOS) in 1994, it was intended to serve as a means of universal ocean governance in resolving international maritime disputes. However, the failure to resolve the ongoing South China Sea Dispute, between the neighboring countries of China, Taiwan, Vietnam, Malaysia, Indonesia, Brunei, and the Philippines, has revealed regulatory gaps on the part of global ocean governance. This paper identifies the origins of gridlock in global ocean governance by identifying the diverging national interests of the actors involved in the South China Sea dispute that hinder cooperation in the region. Furthermore, this paper will show how the legacy of UNCLOS has stifled its own ability to mediate this contemporary conflict. In conclusion, this paper asserts that the key to resolving the South China Sea dispute is through multilateral natural resource extraction between the actors involved in the conflict, aided by the legal and diplomatic support of UNCLOS.
随着1994年《联合国海洋法公约》(UNCLOS)的批准,它旨在成为解决国际海洋争端的普遍海洋治理手段。然而,中国、台湾、越南、马来西亚、印度尼西亚、文莱和菲律宾等邻国之间的南海争端未能得到解决,暴露出全球海洋治理的监管缺口。本文通过识别南中国海争端中阻碍该地区合作的各方不同的国家利益,确定了全球海洋治理僵局的根源。此外,本文将展示《联合国海洋法公约》的遗产如何扼杀了其调解当代冲突的能力。综上所述,本文认为解决南海争端的关键是在《联合国海洋法公约》的法律和外交支持下,通过冲突各方之间的多边自然资源开采。
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引用次数: 0
The Greek Voyage 希腊航行
Pub Date : 2019-05-26 DOI: 10.15367/PJ.V5I2.207
Panagiotis Tzumakaris
During the spring semester of 2018, I took History 4497, a writing intensive course with an emphasis on European travel writing. My research focused on English travel writers of the late 16th and early 17th centuries voyaging to Greece. In my analysis, I examine the interactions early English travel writers experienced with the peoples of Greece. These interactions not only allow for an interesting first-hand insight of Greek life but provide reflections of the authors and their culture. Major themes discussed in my analysis include the anti-Greek bias, civilization versus barbarism, and non-elitist perception. I came to the conclusion that while formally-educated English travel writers’ perceptions of Greece were influenced greatly by the negative biases of their teachings, Thomas Dallam, an English organ-builder with no classical knowledge nor formal education, experienced his Greek voyage with a radically different perspective.
在2018年春季学期,我选修了历史4497,这是一门写作强化课程,重点是欧洲旅行写作。我的研究重点是16世纪末和17世纪初前往希腊的英国旅行作家。在我的分析中,我考察了早期英国旅行作家与希腊人民的互动。这些互动不仅提供了对希腊生活有趣的第一手见解,而且提供了对作者及其文化的反思。在我的分析中讨论的主要主题包括反希腊偏见,文明与野蛮,以及非精英主义的看法。我得出的结论是,虽然受过正规教育的英国旅行作家对希腊的看法在很大程度上受到他们教导的负面偏见的影响,但托马斯·达拉姆(Thomas Dallam),一个既没有古典知识也没有受过正规教育的英国风琴制造者,以一种完全不同的视角经历了他的希腊之旅。
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引用次数: 0
Foreign Born Populations and Unemployment in the United States: Myth or Reality? 外国出生人口与美国失业:神话还是现实?
Pub Date : 2019-05-26 DOI: 10.15367/PJ.V5I2.202
Steven Doncaster
Immigration to the United States has played a crucial role in the founding and development of the nation. However, there has also been a consistent trend of native born United States citizens to pin employment struggles on new immigrant populations. In the wake of the 2016 presidential election and the rhetoric espoused about immigrants, the relationship between new immigrant populations and employment has continued. Is there a relationship between areas with high foreign born populations and high unemployment? By conducting a regression analysis using U.S. Congressional districts as the unit of analysis, I find that there does appear to be a statistically significant relationship between areas with high foreign born populations and high unemployment rates. However, there appears to be a more statistically significant and larger change in the unemployment rate caused by median family incomes and the commuting time to work. I concluded that efforts to better address transportation systems in the United States and addressing income inequality will be more effective at solving unemployment issues than divisive rhetoric towards immigrants. I also recommend that policy initiatives to better integrate new immigrants into U.S. society be studied to curb the relationship between high unemployment areas and high foreign born populations.
移民到美国在国家的建立和发展中发挥了至关重要的作用。然而,本土出生的美国公民也一直将就业困难归咎于新移民人口。在2016年总统大选和支持移民的言论之后,新移民人口与就业之间的关系仍在继续。外国出生人口多的地区和高失业率之间是否存在关系?通过以美国国会选区为分析单位进行回归分析,我发现在外国出生人口多的地区和高失业率之间确实存在统计学上显著的关系。然而,由家庭收入中位数和上班通勤时间引起的失业率似乎在统计上有更显著和更大的变化。我的结论是,更好地解决美国的交通系统问题和解决收入不平等问题,将比针对移民的分裂言论更有效地解决失业问题。我还建议研究将新移民更好地融入美国社会的政策举措,以遏制高失业率地区与高外国出生人口之间的关系。
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引用次数: 0
Loss of Balance: Destructive Legal Mechanisms Within USA Gymnastics Policy and their Contributions to a Toxic and Abusive Environment 失去平衡:美国体操政策中的破坏性法律机制及其对有毒和滥用环境的贡献
Pub Date : 2019-05-26 DOI: 10.15367/PJ.V5I2.208
K. Weaver
Since the 1980’s, USA Gymnastics has emerged as a producer of Olympic champions, international success, and athletic excellence. However, with that growing dominance came a network of sexual abuse perpetuated among individuals at all levels of the organization. This paper seeks to examine the way in which USA Gymnastics allowed such abuse to continue and thrive by creating a system in which athletes were discriminated against in their inability to come forward without fear of retribution. I analyzed the rules and legal mechanisms in place within the organization and how they might prevent athletes and/or their coaches from wishing to come forward. I also sought out instances in which these rules were put into practice or warped for the benefit of abusers and enablers. Ultimately, my research showed that the hierarchy of the organization and the rules it enforced were structured in a way that any athlete wishing to report abuse had to risk being ostracized or not taken seriously. In addition, there were many discreet elements embedded in the culture of the organization, and the sport as a whole, that contributed to a toxic atmosphere that was wholly not conducive to safety and fairness in the practice of reporting abuse.
自20世纪80年代以来,美国体操已经成为奥运会冠军,国际成功和优秀运动员的生产者。然而,随着这种日益增长的统治地位,在组织的各个层面上都存在着一个性虐待网络。本文试图通过建立一种制度来研究美国体操协会允许这种虐待行为继续存在和发展的方式,在这种制度下,运动员因无法在不担心报复的情况下挺身而出而受到歧视。我分析了组织内部的规则和法律机制,以及它们如何阻止运动员和/或他们的教练挺身而出。我还找出了这些规则被付诸实施或被扭曲的例子,以造福于滥用者和推动者。最终,我的研究表明,该组织的等级制度及其执行的规则是这样构建的,任何希望报告虐待行为的运动员都必须冒着被排斥或不被认真对待的风险。此外,该组织和整个体育运动的文化中有许多谨慎的因素,这些因素造成了一种有毒的氛围,这种氛围完全不利于报告虐待行为的安全和公平。
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引用次数: 0
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Nanotechnology Perceptions
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