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Despite recurring calls for diversity and inclusion in adolescent sexuality research, our understanding of adolescents' sexual experiences beyond heteronormative vaginal intercourse remains limited. The current study examined orgasm (during masturbation and with a partner) and sexual behaviors (providing and receiving manual and oral stimulation) in middle adolescents. We conducted logistic regression and path analyses separately for cisgender (n = 2738) and transgender/non-binary (TNB) youth (n = 62) to explore gender and dyad type (intersection between gender and partner gender) differences among 2800 Canadian adolescents (51.4% cisgender girls, M_age = 16.41, SD_age = 0.55). With cisgender boys as reference, cisgender girls had lower odds of experiencing orgasm during masturbation, reported more difficulties with orgasm during partnered sex, received more manual sex, and less oral sex. TNB individuals assigned male at birth received more manual stimulation, and TNB assigned female at birth received less oral sex. For dyad type, compared to cisgender boys partnered with a girl, cisgender girls partnered with a boy and cisgender girls with a gender diverse partner (i.e., non-binary, trans, genderfluid or agender) had lower odds of having ever experienced orgasm during masturbation, reported more difficulties experiencing orgasm during partnered sex, and received oral stimulation less often. Cisgender girls who were partnered with a girl did not differ from cisgender boys who were partnered with a girl. Findings may inform programs that promote sexual wellbeing among youth.

Geography is a well-known factor shaping genetic variation in human populations. However, the potential role played by cultural variables remains much understudied. This study investigates the impact of socio-cultural variables on genomic similarity and the saliva microbiome, using data from populations in Lesotho and Namibia. Geographic distance within Lesotho increases genetic differentiation, while shared clan affiliation surprisingly increases it. In Namibia, ethnicity is the predominant factor influencing genetic affinity. Saliva metagenomic data shows a negative correlation between age and alpha diversity, with notable differences in host-interacting taxa and viral load. These findings highlight the role of geography in shaping genetic affinity even at small scales and the complex influences of cultural factors. The saliva microbiome appears primarily affected by unrecorded individual behaviors rather than geographic or cultural variables. At population-level these oral microbiomes reveal insights into some dietary habits, oral health, and also the communal viral load, which appears to have greater incidence in Lesotho possibly related to the long-term effects of the HIV epidemic in the country.

What does a postcolonial inquiry into technoscience do? And what is it for? I develop these questions by reconsidering one powerful idea: that science and technology studies (STS) is postcolonial when it elucidates the hybridity, heterogeneity, and indeterminacy of global technoscientific formations, and does so to falsify colonial fantasies of hegemony expressed in imperious conceptual generalities and sovereign universalisms. Revisiting Warwick Anderson's expositions of postcolonial STS-initiated in this journal two decades ago-I reflect on the form and force of this critical operation. Despite an animating aversion to universalisms, the pursuit of hybridity and heterogeneity may ultimately universalize a liberal metaphysics of agency. This paradox suggests limits to the critical operation that pits hybridity and indeterminacy against hegemony in a postcolonial spirit.