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The Genomics of Liposarcoma: A Review and Commentary 脂肪肉瘤的基因组学研究综述与评述
Pub Date : 2022-12-28 DOI: 10.34257/gjsfrgvol22is2pg15
Hannah C. Beird, A. Lazar, Danh D. Truong
Soft tissue sarcomas STS are malignancies that show mesenchymal and neuroectodermal differentiation and thus most often resemble supportive and connective tissue including fat blood vessels muscle bone tendons and nerves Over 70 subtypes of sarcomas exist and pathologists have classified these broadly according to the degree to which they resemble differentiated cell types Figure 1 1 This review will focus on the most common subset of STS in adults liposarcoma which are tumors with histological features of specialized fat cells Liposarcoma are broken down into several subtypes The four with the highest incidence are welldifferentiated liposarcoma WDLPS dedifferentiated liposarcoma DDLPS myxoid liposarcoma MLPS and pleomorphic liposarcoma PLPS 1 Overall survival is highest for MLPS followed by WDLPS and DDLPS and then PLPS2-4 Figure 2 While WDLPS occurs predominantly in the deep soft tissues of the limbs and retroperitoneum DDLPS is located mostly in the retroperitoneum MLPS and PLPS are preferentially located within the limbs5 Despite these broad categories liposarcoma can also have mixed phenotypes and is often further subdivided into even more rare entities with other ultra-rare features For instance pleomorphic MLPS has attributes of both PLPS and MLPS6,7.
软组织肉瘤是一种表现为间质和神经外胚层分化的恶性肿瘤,因此最常类似于支持性组织和结缔组织,包括脂肪、血管、肌肉、骨、肌腱和神经。肉瘤有70多种亚型,病理学家根据它们与分化细胞类型的相似程度对它们进行了广泛的分类专业脂肪细胞脂肪肉瘤的特点分为几个亚型发病率最高的四个welldifferentiated脂肪肉瘤WDLPS肉瘤脂肪肉瘤DDLPS黏液样脂肪肉瘤mlp和多形性脂肪肉瘤PLPS 1总体存活率最高mlp紧随其后WDLPS DDLPS然后PLPS2-4图2虽然WDLPS主要发生在四肢和腹膜后腔的深度软组织DDLPS来说位于腹膜后腔mlp PLPS尽管有这些广泛的分类,脂肪肉瘤也可以具有混合表型,并且通常进一步细分为具有其他超罕见特征的更罕见的实体,例如多形性MLPS具有PLPS和MLPS的属性6,7。
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引用次数: 0
Two-Stage Model of Silicate Glass Transition 硅酸盐玻璃化转变的两阶段模型
Pub Date : 2022-12-12 DOI: 10.34257/gjsfravol22is7pg1
Shangcong Cheng
After several decades of study, the nature of the glass state and glass transition remains controversial. This work describes a newly proposed two-stage model for silicate glass transition. The model recognizes that there is a cooling rate independent critical temperature Tc, separating two temperature regions. The coherent structures in the two regions change along different paths. All observed dynamic features in the glass transition result from structural rearrangements in the process. According to the proposed model, the silicate glass transition can be recognized as a second-order phase transition following an incomplete first-order phase transition. This work will first describe the two-stage model, and then apply the model to silica glass, as well as binary and ternary silicate glass transitions.
经过几十年的研究,玻璃态和玻璃化转变的性质仍然存在争议。这项工作描述了一个新提出的两阶段模型的硅酸盐玻璃转变。该模型识别出存在一个与冷却速率无关的临界温度Tc,将两个温度区域分开。两个区域的相干结构沿着不同的路径变化。所有观察到的玻璃化转变的动态特征都是由过程中的结构重排引起的。根据所提出的模型,硅酸盐玻璃相变可以被认为是在不完全的一级相变之后的二级相变。这项工作将首先描述两阶段模型,然后将该模型应用于硅玻璃,以及二元和三元硅酸盐玻璃的转变。
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引用次数: 0
Noncommutative Quantum Gravity and Symmetry of Klein-Gordon Equation 非交换量子引力与Klein-Gordon方程的对称性
Pub Date : 2022-12-12 DOI: 10.34257/gjsfravol22is7pg19
Gangrok Lee
In the paper ’A New Approach to Quantum Gravity’[1], we suggest a new approach to quantum gravity. Using this theory, we can study the noncommutative gravitational field in momentum space. In this paper, we obtain the general form of the Klein-Gordon equation in noncommutative gravitational field. Then we find the symmetry associated with noncommutative gravity from the Klein-Gordon equation. We study black hole in momentum space and conclude that the event horizon of black holes is formed by the dipoles in momentum space with limit state.
在论文“A New Approach to Quantum Gravity”[1]中,我们提出了一种新的量子引力方法。利用这一理论,我们可以研究动量空间中的非对易重力场。本文得到了非对易引力场中Klein-Gordon方程的一般形式。然后我们从Klein-Gordon方程中找到与非对易引力相关的对称性。我们研究了动量空间中的黑洞,得出了黑洞的视界是由具有极限状态的动量空间中的偶极子形成的结论。
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引用次数: 0
Green Spaces in Sana’a Old City - Yemen between Past to Present 萨那老城的绿地——也门从过去到现在
Pub Date : 2022-11-30 DOI: 10.34257/gjsfrhvol22is7pg11
S. AlShawesh, Nada Ibraheem Al-Abyad
The presence of nature was evident in the cities and villages of Yemen - a country located on the southern tip of the Arabian Peninsula - with a varied topography between mountains, plains, deserts, and islands. Formerly Yemen was given many names. For example, the Greeks and Romans called it "Arabia Felix'', while Arab historians called it "green Yemen” due to its fertility, greenness, and picturesque nature. Ancient Yemeni settled in good geographical areas with suitable natural conditions and practised agriculture. Despite the rugged terrain of the mountainous heights, he built agricultural terraces on the mountains and found irrigation systems, so he dug wells and built dams such as the Ma’arib dam.
也门是一个位于阿拉伯半岛南端的国家,在也门的城市和村庄中,自然的存在是显而易见的,它的地形在山脉、平原、沙漠和岛屿之间变化多样。以前也门有很多名字。例如,希腊人和罗马人将其称为“阿拉伯菲利克斯”,而阿拉伯历史学家则将其称为“绿色也门”,因为它肥沃,绿色,风景如画。古也门人定居在地理位置优越、自然条件适宜的地区,从事农业生产。尽管山区地势崎岖,但他在山上建造了农业梯田,发现了灌溉系统,因此他挖井并建造了水坝,如Ma 'arib水坝。
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引用次数: 0
Ecosystems in a State of Flux: Evidence from A Kenyan Coastal Riparian Ecosystem 处于变化状态的生态系统:来自肯尼亚沿海河岸生态系统的证据
Pub Date : 2022-11-30 DOI: 10.34257/gjsfrhvol22is7pg31
E. Maranga, Leila Ndalilo
Riparian ecosystems are considered hotspots of carbon and nitrogen transformations. These biochemical transformations are driven by anthropogenic activities in the immediate riverine water catchments. The anthropogenic activities may include and not limited to extraction of goods such as agricultural products, wood products, honey, plant based pharmaceutical products, livestock products, firewood, water and grass for thatching homesteads. Riparian ecosystems also provide important tangible and intangible ecosystem services comprising spiritual and aesthetic functions, pollination, ecosystem detoxification functions, carbon and nitrogen sequestration and CO2 sinks for amelioration of climate change impacts among others. These ecosystems are increasingly threatened by degradation attributed to land use changes. Human perturbations such as crop farming on riparian land, overgrazing and population pressure on land resources influence degradation of riparian ecosystems, with profound effects on biodiversity conservation and local livelihoods. Evidence from the literature indicates that although there is a general understanding regarding the response of terrestrial and wetland ecosystems to human perturbations, there is a dearth of information on the response of African riparian ecosystems to ecologic and socio-economic impacts.
河岸生态系统被认为是碳和氮转化的热点。这些生化变化是由邻近河流集水区的人为活动驱动的。这些人为活动可以包括但不限于对农产品、木制品、蜂蜜、植物性药品、畜产品、柴火、水和茅草等商品的提取。河岸生态系统还提供重要的有形和无形的生态系统服务,包括精神和审美功能、授粉、生态系统解毒功能、碳和氮固存以及改善气候变化影响的二氧化碳汇等。这些生态系统日益受到土地利用变化导致的退化的威胁。河岸土地上的作物种植、过度放牧和人口对土地资源的压力等人为干扰会影响河岸生态系统的退化,对生物多样性保护和当地生计产生深远影响。来自文献的证据表明,尽管对陆地和湿地生态系统对人类扰动的响应有一个普遍的认识,但关于非洲河岸生态系统对生态和社会经济影响的响应的信息缺乏。
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引用次数: 0
Gauge-Theoretic Study of Kundt Tube Experiment and Spontaneous Symmetry Transitions 昆特管实验和自发对称跃迁的规范理论研究
Pub Date : 2022-11-17 DOI: 10.34257/gjsfravol22is6pg61
T. Kambe
In the Kundt’s experiment of acoustic resonance in closed tubes, two characteristic lengths were observed: one is the wave-length of the sound waves in resonance and the other the scale of dust striation. The latter has remained unresolved for its formation mechanism. Based on the Fluid Gauge Theory proposed recently by the author, formation mechanism of the dust striation is studied. When the sound is weak enough, the striation is unobserved. Once the wave intensity exceeds a threshold value, dust striations are formed. Formation of the dust striation is understood as a spontaneous transition of symmetry in the acoustics. According to the Theory, there is a transition of stress field within the fluid flow. Whereas the stress field is isotropic before transition, it becomes anisotropic after the transition. This is analogous to the spontaneous symmetry breaking known in the field theory. Lagrangian structures of both systems are verified to be analogous either.
在昆特的闭管声共振实验中,观察到两个特征长度:一个是共振声波的波长,另一个是尘埃条纹的尺度。后者的形成机制尚未得到解决。基于作者最近提出的流体测量理论,对粉尘条纹的形成机理进行了研究。当声音足够微弱时,条纹是不可见的。一旦波强度超过阈值,就会形成粉尘条纹。尘埃条纹的形成可以理解为声学中对称性的自发转变。根据该理论,流体流动中存在应力场的过渡。转变前应力场为各向同性,转变后应力场为各向异性。这类似于场论中已知的自发对称性破缺。验证了两个系统的拉格朗日结构是相似的。
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引用次数: 0
Active Control of Stick-Slip Torsional Vibrations of Drill-Strings using Non-Switching Sliding Mode Controller 基于非切换滑模控制器的钻柱粘滑扭振主动控制
Pub Date : 2022-11-17 DOI: 10.34257/gjsfravol22is6pg1
A. Baz
Torsional vibrations of drill-strings are actively controlled using a non-switching sliding mode strategy. The controller is intended also to reject the effect of the interaction between the drill-bit and rock formation which induces non-linear stick-slip friction torque while tracking a desirable constant angular velocity of the drill-string. In order to demonstrate the merits of the proposed control algorithm, it is integrated with a simple two degrees-of-freedom model of the drill-string which is considered as a benchmark model for studying stick-slip induced torsional vibrations. Details of the development of the individual components making up the entire control action of the sliding mode controller (SMC) are presented. These components aim at rejecting the effect of the external disturbance of the stick-slip disturbance and tracking a reference angular velocity of the drill-string. Such development of the control action components is established using Lyapunov stability criterion. Numerical examples are presented to demonstrate the effectiveness of the SMC controller as influenced by the weight-on-bit (WOB), the drill-string rotational speed, and the main parameters of the controller. The stick-slip sensitivity (SSS) maps are developed to illustrate the performance characteristics of the active system for different operating conditions and important design parameters of the SMC. The presented active control approach is envisioned to present an invaluable and practical means for effectively mitigating the undesirable effects of stick-slip frictional disturbances on drill-stings.
采用非切换滑模策略主动控制钻柱扭振。该控制器还旨在抑制钻头与岩层之间相互作用的影响,这种相互作用会在跟踪钻柱的理想恒定角速度时产生非线性粘滑摩擦扭矩。为了证明所提出的控制算法的优点,将其与钻柱的简单二自由度模型相结合,该模型被认为是研究粘滑诱导扭转振动的基准模型。详细介绍了构成滑模控制器(SMC)整个控制动作的各个元件的开发。这些组件的目的是抵制粘滑干扰的外部干扰的影响,并跟踪钻柱的参考角速度。利用李亚普诺夫稳定性判据建立了控制作用分量的发展。数值算例表明,在钻压(WOB)、钻柱转速和控制器主要参数的影响下,SMC控制器是有效的。为了说明主动系统在不同工况和SMC重要设计参数下的性能特征,建立了粘滑灵敏度(SSS)图。所提出的主动控制方法有望为有效减轻粘滑摩擦扰动对钻柱的不良影响提供宝贵而实用的手段。
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引用次数: 0
A Semi-Empirical Model of Winter Wheat Grain Protein Content 冬小麦籽粒蛋白质含量的半经验模型
Pub Date : 2022-11-15 DOI: 10.34257/gjsfrcvol22is2pg1
Qian Wang, Cunjun Li, Yuanpi Huang, Wude Yang, Wen-jiang Huang, Ji‐Hua Wang
Winter wheat grain protein content (GPC) is an important criterion for assessing grain quality. A timely and simple GPC model is urgently required for GPC prediction ahead of maturity. The GPC model included regressional models of dry matter and N accumulation and translocation for anthesis and post-anthesis stages, and incorporated both soil nitrogen (N) supply and meterological factors based on historical as well as current season data, final GPC were calculated as the ratio of N accumulation to dry matter in grain at maturity. This study conducted six field experiments during the 2003–2006 and 2008–2011 growing seasons to establish and validate the model. A three-way factorial arrangement of N fertilization, sowing date, and cultivar was conducted using a split-plot design. Critical growth parameters were determined by field measurements, and historical seasonal meteorological data covering the growing period were collected.
冬小麦籽粒蛋白质含量(GPC)是评价籽粒品质的重要指标。为了在GPC成熟前进行预测,迫切需要一个及时、简单的GPC模型。GPC模型包括开花和花期后干物质和氮积累及转运的回归模型,并结合历史和当季数据,考虑土壤氮供应和气象因素,最终计算GPC为成熟期籽粒氮积累与干物质之比。本研究在2003-2006年和2008-2011年生长季进行了6次田间试验,建立并验证了该模型。采用分畦设计对施氮量、播期和品种进行三因子安排。通过野外测量确定了关键生长参数,并收集了生长期的历史季节气象资料。
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引用次数: 0
Ethno-Botanical Study at the Nabiganj Upazila of Habiganj District, Bangladesh 孟加拉国Habiganj地区Nabiganj Upazila的民族植物学研究
Pub Date : 2022-11-15 DOI: 10.34257/gjsfrcvol22is2pg17
Jontu Chandra Deb
Between August 2019 and October 2020, an ethnobotanical research was carried out to look at how the inhabitants of Nabiganj Upazila of Bangladesh's Habiganj district was noted. The information regarding the ethnobotanical data was obtained by interviewing residents of different age groups, most of them were in the 15 to 55 age range, including medicinal herbalists and hakims. The present paper reported that 68 medicinal plants belonging to 41 families, and 60 genera which have been proven to be helpful in the treatment of 78 diseases. Out of these plant species, 24 belonged to herbs, 27 trees, eight shrubs, and nine climbers. However, other parts of medicinal plants, including the stem, bark, latex, leaf bud, pulp, petiole, fruits, and rhizome, Seed, root, calyx, and peduncle were also shown to be helpful. For each species, scientific name, local name, habit, family, ailments to be treated, mode of treatment, and part(s) used are provided. Local residents of gathered data on medicinal plants, including Nabiganj Upazila of Habiganj district.
在2019年8月至2020年10月期间,进行了一项民族植物学研究,以了解如何注意孟加拉国哈比甘杰地区Nabiganj Upazila的居民。民族植物学方面的资料是通过对不同年龄组的居民进行访谈获得的,访谈对象大多在15 - 55岁之间,包括中草药医师和哈基姆。本文报道了68种药用植物,隶属于41科60属,已证实对78种疾病有治疗作用。其中,草本植物24种,乔木植物27种,灌木植物8种,攀缘植物9种。然而,药用植物的其他部分,包括茎、树皮、乳胶、叶芽、果肉、叶柄、果实和根茎、种子、根、花萼和花梗也被证明是有帮助的。对于每个物种,提供了学名,当地名称,习惯,家庭,要治疗的疾病,治疗方式和使用的部件。当地居民收集了药用植物的数据,包括Habiganj区的Nabiganj Upazila。
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引用次数: 0
Long-Term Soil FertilityChangesFollowing Thermal Desorption to RemoveCrude Oil are Favorable to Revegetation Strategies 热解吸去除原油后土壤肥力的长期变化有利于植被恢复策略
Pub Date : 2022-11-07 DOI: 10.34257/gjsfrhvol22is6pg1
J. Mowrer, T. Provin, Steven M. Perkins
Heat treatment is effective for removing petroleum hydrocarbons from soil. However, high heat reduces the fertility of soils. This study determined the effect of temperature, and crude oil and salt additions on the fertility of four soils. Effects were assessed immediately after thermal treatment and following an equilibration/stabilization period. Soils were heated at four controlled temperatures (65, 300, 425, and 550°C) and also in an uncontrolled smoldering device, with 0 or 50 g kg-1oil added and with 3 levels of salt solution added (0, 1, or 3 ms cm-1). Soils were ‘rapidly weathered’ via wet/dry cycles at 37°C for five weeks. Initial changes in soil fertility were extreme enough to inhibit plant growth. Soil pH values were positively related to temperature, exceeding pH 8.5 at 550°C. The severity of changes was markedly reduced following incubations, showing that post heat treatment fertility will rebound with time and water.
热处理对去除土壤中的石油烃是有效的。然而,高温降低了土壤的肥力。本研究测定了温度、原油和盐添加量对四种土壤肥力的影响。在热处理后和平衡/稳定期后立即评估效果。土壤在四种受控温度下加热(65、300、425和550°C),也在不受控制的阴燃装置中加热,添加0或50 g kg-1油,并添加3级盐溶液(0,1或3 ms cm-1)。土壤在37°C的干湿循环中“快速风化”了5周。土壤肥力最初的变化极端到足以抑制植物生长。土壤pH值与温度呈正相关,在550℃时pH值超过8.5。在孵育后,变化的严重程度显著降低,表明热处理后的生育力会随着时间和水分的增加而反弹。
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引用次数: 0
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Global Journal of Science Frontier Research
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