Scientists have begun using AI agents in tasks such as reviewing the published literature, formulating hypotheses and subjecting them to virtual tests, modeling complex phenomena, and conducting experiments. Although AI agents are likely to enhance the productivity and efficiency of scientific inquiry, their deployment also creates risks for the research enterprise and society, including poor policy decisions based on erroneous, inaccurate, or biased AI works or products; responsibility gaps in scientific research; loss of research jobs, especially entry-level ones; the deskilling of researchers; AI agents’ engagement in unethical research; AI-generated knowledge that is unverifiable by or incomprehensible to humans; and the loss of the insights and courage needed to challenge or critique AI and to engage in whistleblowing. Here, we discuss these risks and argue that, for responsible management of them, reflection on which research tasks should and should not be automated is urgently needed. To ensure responsible use of AI agents in research, institutions should train researchers in AI and algorithmic literacy, bias identification, and output verification, and should encourage understanding of the risks and limitations of AI agents. Research teams may benefit from designating an AI-specific role, such as an AI validator expert or AI guarantor, to oversee and take responsibility for the integrity of AI-assisted contributions.
Cicero's treatise On Old Age offers an optimistic account of aging and responds to the prejudiced arguments of those who might otherwise ridicule older members of Roman society. While Cicero's rhetoric is, at times, scientifically naive and moralistic, this article argues that there are important insights that can be gained from carefully theorizing later life as a distinct and valuable stage of human existence—a stage of life that ought not be reduced to a mere proxy for health risk. A careful analysis provides insight into the conditions for flourishing in later life notwithstanding a more pronounced expression of the aging process. Some scholars downplay possibilities for agency and meaning in later life and foreground dignity as an overarching value for old age. We argue, however, that agency and meaning are not only possible but also central in later life but must be supported by social relationships that enhance well-being and the pursuit and realization of life goals.

