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The present situation of and challenges in research ethics and integrity promotion: Experiences in East Asia. 促进研究伦理与诚信的现状与挑战:东亚的经验。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2024-08-01 Epub Date: 2023-01-15 DOI: 10.1080/08989621.2022.2155144
Chien Chou, In Jae Lee, Jun Fudano

As relatively new economies to the global research arena, East Asian nations have fully realized the importance of research integrity in recent decades. This article conducts document analysis to demonstrate and discuss the current situation of research integrity campaigns in Taiwan, Korea, and Japan, nations that have similar cultural backgrounds and socioeconomic statuses. This article emphasizes the common situations faced by these three nations both individually and collectively. Based on a four-pillar framework, research integrity campaigns in these nations are making progress in terms of policies and regulations, institutional management, researchers' education and training, and the handling of misconduct cases. Various issues and challenges have also emerged in this context, although these efforts may have had positive impacts on research communities in these three nations. Challenges associated with research integrity governance, institutional willingness, RCR instructor qualifications, the effectiveness of education, and the standardization of definitions of misconduct and noncompliance are also highlighted. The issues discussed in this article are expected to have implications for research communities and policy-makers in these three nations as well as in a global context.

作为全球研究领域相对较新的经济体,东亚各国在近几十年中充分认识到了研究诚信的重要性。本文通过文献分析,展示并讨论了文化背景和社会经济地位相似的台湾、韩国和日本的科研诚信运动现状。本文强调了这三个国家各自和共同面临的共同情况。基于四大支柱框架,这些国家的科研诚信运动在政策法规、机构管理、科研人员教育培训和不当行为案件处理等方面都取得了进展。尽管这些努力可能对这三个国家的研究界产生了积极影响,但在这方面也出现了各种问题和挑战。本文还强调了与研究诚信管理、机构意愿、RCR 讲师资格、教育的有效性以及不当行为和违规行为定义的标准化有关的挑战。本文讨论的问题预计将对这三个国家以及全球范围内的研究界和政策制定者产生影响。
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引用次数: 0
A comprehensive overview of studies that assessed article retractions within the biomedical sciences. 对生物医学领域文章撤稿情况进行评估的研究综述。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2024-08-01 Epub Date: 2023-01-15 DOI: 10.1080/08989621.2022.2154660
Carla Brigitte Susan Kohl, Clovis Mariano Faggion

This study aims to provide a comprehensive overview of previous research that has investigated retractions within the biomedical fields and assess their methodological quality. We searched three major electronic databases for articles on retractions within the biomedical field: PubMed, Web of Science, and Scopus. In total, 162 articles were included in the analysis. We evaluated their methodological quality using the items of "a measurement tool to assess systematic reviews" (AMSTAR-2) checklist and the Cochrane guidance. The studies had been published in more than 20 biomedical disciplines or fields of investigation, and two-thirds were published after 2017. Concerning methodology, none of the studies fulfilled all the suggested items; five studies did not meet any of the suggested AMSTAR-2 categories or Cochrane guidelines. The most prevalent reported reasons for retraction were fraud and plagiarism (21.0%). In summary, there has been increasing interest in assessing the characteristics and impact of retractions in the biomedical sciences. The studies cited types of misconduct more often than honest errors as a major reason for retraction. The methodological quality of the existing studies in this area appears to be suboptimal. Future investigators should improve upon this, particularly in the quality of the data selection and extraction.

本研究旨在全面概述以往对生物医学领域撤稿行为的调查研究,并评估其方法论质量。我们在三大电子数据库中搜索了有关生物医学领域撤稿的文章:PubMed、Web of Science 和 Scopus。共有 162 篇文章被纳入分析。我们使用 "评估系统性综述的测量工具"(AMSTAR-2)清单和 Cochrane 指南对这些文章的方法学质量进行了评估。这些研究发表于20多个生物医学学科或研究领域,其中三分之二发表于2017年之后。在方法学方面,没有一项研究符合所有建议的项目;有五项研究不符合AMSTAR-2建议的任何类别或Cochrane指南。据报告,撤稿最普遍的原因是欺诈和剽窃(21.0%)。总之,人们对评估生物医学领域撤稿的特点和影响越来越感兴趣。与诚实的错误相比,这些研究更多地将不当行为作为撤稿的主要原因。该领域现有研究的方法质量似乎不够理想。未来的研究人员应在这方面加以改进,特别是在数据选择和提取的质量方面。
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引用次数: 0
Creating research ethics and integrity country report cards: Case study from Europe. 创建研究伦理与诚信国家报告单:欧洲案例研究。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2024-08-01 Epub Date: 2023-01-17 DOI: 10.1080/08989621.2022.2163632
Andrijana Perković Paloš, Rea Roje, Vicko Tomić, Ana Marušić

Structures for and practices of research integrity (RI) and research ethics (RE) differ among countries. This study analyzed the processes and structures for RI and RE in Europe, following the framework developed at the World Conferences on Research Integrity. We present RI and RE Country Report Cards for 16 European countries, which included the information on RI and RE structures, processes and outcomes. While some of the countries are front-runners when it comes to RI and RE, with well-established and continually developing policies and structures, others are just starting their journey in RI and RE. Although RI and RE contextual divergences must be taken into account, a level of harmonization among the countries is necessary so that researchers working in the European area can similarly handle RI and RE issues and have similar expectations regardless of the organization in which they work. RI and RE Country Report Cards can be a tool to monitor, compare, and strengthen RE and integrity across countries through empowerment and inspiration by examples of good practices and developed systems.

各国的研究诚信(RI)和研究伦理(RE)结构和实践各不相同。本研究按照世界科研诚信大会制定的框架,分析了欧洲的 RI 和 RE 流程与结构。我们提交了 16 个欧洲国家的 RI 和 RE 国家报告卡,其中包括有关 RI 和 RE 结构、流程和结果的信息。其中一些国家在 RI 和 RE 方面走在前列,拥有完善并不断发展的政策和结构,而另一些国家在 RI 和 RE 方面刚刚起步。虽然必须考虑到 RI 和 RE 的背景差异,但各国之间也有必要进行一定程度的协调,以便在欧洲地区工作的研究人员能够以类似的方式处理 RI 和 RE 问题,并且无论他们在哪个组织工作,都有类似的期望。RI 和 RE 国家报告卡可以成为监测、比较和加强各国 RE 和诚信的工具,通过良好做法和已开发系统的范例进行赋权和激励。
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引用次数: 0
The Uniform Determination of Death Act is Not Changing. Will Physicians Continue to Misdiagnose Brain Death? 统一死亡判定法》不会改变。医生会继续误诊脑死亡吗?
IF 17 1区 哲学 Q1 ETHICS Pub Date : 2024-07-05 DOI: 10.1080/15265161.2024.2371129
Michael Nair-Collins

Efforts to revise the Uniform Determination of Death Act in order to align law with medical practice have failed. Medical practice must now align with the law. People who are not dead under the law that defines death should not be declared dead. There is no compelling reason to continue the practice of declaring legally living persons to be dead.

为使法律与医疗实践相一致而修订《统一死亡判定法》的努力已经失败。现在,医疗实践必须与法律保持一致。根据定义死亡的法律,未死亡的人不应被宣布死亡。没有令人信服的理由继续将合法活着的人宣布为死亡。
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引用次数: 0
An ERP Study on the Processing of Subject-Verb and Object-Verb Gender Agreement in Punjabi. 旁遮普语中主语-动词和宾语-动词性别一致处理的 ERP 研究。
IF 1.6 2区 文学 Q1 LINGUISTICS Pub Date : 2024-07-05 DOI: 10.1007/s10936-024-10095-4
Mahima Gulati, R Muralikrishnan, Kamal Kumar Choudhary

This study was conducted with the aim of exploring the general parsing mechanisms involved in processing different kinds of dependency relations, namely verb agreement with subjects versus objects in Punjabi, an SOV Indo-Aryan language. Event related brain potentials (ERPs) were recorded as twenty-five native Punjabi speakers read transitive sentences. Critical stimuli were either fully acceptable as regards verb agreement, or alternatively violated gender agreement with the subject or object. A linear mixed-models analysis confirmed a P600 effect at the position of the verb for all violations, regardless of whether subject or object agreement was violated. These results thus suggest that an identical mechanism is involved in gender agreement computation in Punjabi regardless of whether the agreement is with the subject or the object argument.

本研究旨在探索旁遮普语(一种 SOV 印度-雅利安语)中处理不同类型依存关系(即动词与主语和宾语一致)时所涉及的一般解析机制。在 25 位以旁遮普语为母语的人阅读及物动词句子时,记录了与事件相关的脑电位(ERP)。临界刺激要么在动词一致方面完全可接受,要么违反了与主语或宾语的性别一致。线性混合模型分析证实,无论违反的是主语还是宾语的一致,在所有违反的动词位置上都存在 P600 效应。因此,这些结果表明,在旁遮普语中,不论是与主语还是宾语参数的一致,性别一致的计算都涉及到一个相同的机制。
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引用次数: 0
On "intent" in research misconduct. 关于研究不当行为中的 "意图"。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2024-07-04 DOI: 10.1080/08989621.2024.2374577
Nicole Shu Ling Yeo-Teh, Bor Luen Tang

Research misconduct, broadly defined as acts of fabrication, falsification and/or plagiarism, violate the value system of science, cost significant wastage of public resources, and in more extreme cases endanger research participants or members of the society at large. Determination of culpability in research misconduct requires establishment of intent on the part of the respondent or perpetrator. However, "intent" is a state of mind, and its perception is subjective, unequivocal evidence for which would not be as readily established compared to the objective evidence available for the acts themselves. Here, we explore the concept of "intent" in research misconduct, how it is framed in criminological/legal terms, and narrated from a psychological perspective. Based on these, we propose a framework whereby lines of questioning and investigation, as defined by legislative terms and informed by the models and tools of psychology, could help in establishing a preponderance of evidence for culpable intent. Such a framework could be useful in research misconduct adjudications and in delivering sanctions.

研究不当行为的广义定义是捏造、篡改和/或剽窃行为,这些行为违反了科学的价值体系,严重浪费了公共资源,在更极端的情况下还会危及研究参与者或社会大众。要确定研究不当行为的罪责,就必须确定答辩人或行为人的意图。然而,"意图 "是一种心理状态,对它的认知是主观的,与行为本身的客观证据相比,不那么容易获得明确的证据。在此,我们将探讨科研不端行为中的 "意图 "概念,以及如何从犯罪学/法律角度对其进行界定,并从心理学角度对其进行阐述。在此基础上,我们提出了一个框架,根据该框架,由立法术语定义并借鉴心理学模型和工具的提问和调查思路,可以帮助确立应受处罚意图的优势证据。这样一个框架可以在研究不当行为的裁决和制裁中发挥作用。
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引用次数: 0
Pass the tissue: restoring researcher access to legal human donations. 传递组织:恢复研究人员获得合法人体捐赠的途径。
IF 3.3 2区 哲学 Q1 ETHICS Pub Date : 2024-07-04 DOI: 10.1136/jme-2023-109033
Meredith Leston, Simon De Lusignan, Richard Frederick Hobbs

The sensitivity of human tissue and previous instances of misuse have, rightfully, led to the introduction of far-reaching oversight and regulatory mechanisms for accessing, storing and sharing samples. However, these restrictions, in tandem with more broad-based privacy regulations, have had the unintended consequence of obstructing legitimate requests for medical materials. This is of real detriment to ambitions for biomedical research, most notably the precision medicine agenda. As such, this paper makes the case for facilitating authorised researcher access to human tissue and associated data along practical medical ethics lines, detailing how liberating samples from unfit regulations, re-evaluating biobanks, diversifying considerations for donor benefit-risk, future proofing donor consent and flattening hierarchies of donation acceptability equate to a more cohesive and respectful means of managing biological samples and information than is achieved at present.

人体组织的敏感性和以前发生的滥用事件,理所当然地导致了对样本的获取、储存和共享实行意义深远的监督和管理机制。然而,这些限制措施与基础更为广泛的隐私条例一起,产生了意想不到的后果,即阻碍了对医疗材料的合法要求。这对生物医学研究的雄心壮志,尤其是精准医学议程,造成了真正的损害。因此,本文从实用的医学伦理角度出发,为经授权的研究人员获取人体组织及相关数据提供便利,详细阐述了如何将样本从不相容的法规中解放出来、重新评估生物库、多样化考虑捐赠者的利益-风险、未来捐赠者的同意以及扁平化捐赠可接受性等级,从而以比目前更有凝聚力、更受尊重的方式管理生物样本和信息。
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引用次数: 0
Responsibility is an adequate requirement for authorship: a reply to Levy. 责任是作者身份的充分条件:对列维的答复。
IF 3.3 2区 哲学 Q1 ETHICS Pub Date : 2024-07-04 DOI: 10.1136/jme-2024-110245
Gert Helgesson, William Bülow

Neil Levy argues in a recent JME 'Current controversy' paper that responsibility is not an adequate authorship requirement for human researchers, which makes it unjustified to require it from artificial intelligence contributing to research and scientific paper production, although he softens his stance towards the end and accepts that a limited responsibility requirement might after all be reasonable. The main argument provided by Levy against a more extensive responsibility requirement in science is that there are many cases where not all researchers listed as coauthors can assume responsibility for the entire paper or even the central research questions. In this reply, we argue that the more limited responsibility requirement is the ethically reasonable one to ask of all authors, considering the conditions for and value of collaboration, and that this should also have ramifications for the legal regulation of scientific misconduct.

尼尔-利维(Neil Levy)在最近发表的一篇 JME "当前争议 "论文中指出,责任并不是对人类研究人员的充分作者资格要求,因此要求人工智能参与研究和科学论文的撰写是不合理的,尽管他在最后软化了自己的立场,承认有限的责任要求可能毕竟是合理的。利维反对在科学领域提出更广泛的责任要求的主要论据是,在很多情况下,并非所有列为共同作者的研究人员都能对整篇论文甚至是核心研究问题承担责任。在本答复中,我们认为,考虑到合作的条件和价值,对所有作者提出较为有限的责任要求在伦理上是合理的,而且这也会对科学不端行为的法律监管产生影响。
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引用次数: 0
Quantum Ontology: A Modal Bundle-Theorist Relational Proposal 量子本体论:模态捆绑理论的关系提议
IF 0.9 4区 哲学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-07-04 DOI: 10.1007/s10699-024-09955-y
Matías Pasqualini

Quantum mechanics poses several challenges in ontological elucidation. Contextuality threatens determinism and favors realism about possibilia. Indistinguishability challenges traditional identity criteria associated with individual objects. Entanglement favors holistic and relational approaches. These issues, in close connection with different interpretations of quantum mechanics, have given rise to various proposals for the ontology of quantum mechanics. There is a proposal that is realistic about possibilia, where quantum systems are seen as bundles of possible intrinsic properties. This proposal is developed in close connection with modal interpretations and addresses quantum contextuality straightforwardly. There are also proposals based on relations, associated with the relational quantum mechanics interpretation. In this paper, features of these proposals are combined to obtain a modal bundle-theorist relational proposal. Its aim is to consistently and straightforwardly address both contextuality and the holistic and relational aspects of quantum mechanics arising from quantum entanglement. The proposal, if some additional principles are assumed, may turn out to be both an instance of moderate structuralism and priority monism.

量子力学在本体论阐释方面提出了若干挑战。情境性对决定论构成威胁,而对可能性则倾向于现实主义。可区分性挑战了与单个对象相关的传统身份标准。纠缠倾向于整体性和关系性方法。这些问题与对量子力学的不同解释密切相关,引发了关于量子力学本体论的各种提议。有一种建议对可能性持现实态度,将量子系统视为可能的内在属性束。这一提议是在与模态解释紧密联系的基础上提出的,并直接解决了量子语境性问题。还有一些基于关系的建议,与关系量子力学解释相关。在本文中,这些建议的特点被结合起来,从而获得了模态束理论的关系建议。其目的是一致而直接地解决量子纠缠所产生的量子力学的语境性、整体性和关系性问题。如果假定有一些额外的原则,那么该建议可能会成为温和结构主义和优先一元论的实例。
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引用次数: 0
Can a human right to good mental health be justified? 享有良好心理健康的人权是否合理?
IF 1.7 2区 哲学 Q2 ETHICS Pub Date : 2024-07-04 DOI: 10.1111/bioe.13329
Phil Bielby

Can a human right to good mental health be justified? This is an under-explored question: until recently, rights in relation to mental health have been framed and debated primarily in terms of their relevance to psychosocial disability and mental ill-health/mental distress. By contrast, in this article, I propose the basis of a normative justification for a population-wide right to good mental health, focusing in particular on individuals who do not experience mental ill-health/distress or do not have (or may never have) a psychiatric diagnosis or a psychosocial disability. The article is structured into three parts. First, I will outline the emergence of a population-wide right to good mental health in mental health discourse, led by recent reports published by the former United Nations Special Rapporteur on the Right to Health, Danius Pūras. I will then go on to explore what we might understand by 'good mental health'. Finally, I will explain how a right to good mental health may be justified, drawing on insights from compassion, 'vulnerable agency', and James Wilson's account of 'a right to public health'. I then respond to feasibility and demandingness concerns about such a right, which together inform the basis of the qualified public health right to good mental health I propose.

享有良好心理健康的人权是否合理?这是一个尚未得到充分探讨的问题:直到最近,与心理健康有关的权利还主要是从其与社会心理残疾和精神疾病/精神痛苦的相关性方面进行阐述和辩论的。相比之下,在这篇文章中,我提出了全民享有良好精神健康权利的规范性理由基础,尤其关注那些没有经历过精神疾病/精神痛苦或没有(或可能永远不会有)精神病诊断或社会心理残疾的个人。本文分为三个部分。首先,我将概述在前联合国健康权特别报告员达尼乌斯-普拉斯(Danius Pūras)最近发表的报告的引领下,精神健康话语中出现的全民良好精神健康权。然后,我将继续探讨我们对 "良好心理健康 "的理解。最后,我将借鉴同情心、"弱势代理 "以及詹姆斯-威尔逊(James Wilson)关于 "公共健康权 "的论述,解释如何为享有良好心理健康的权利提供正当理由。然后,我将对这种权利的可行性和需求性问题做出回应,这些问题共同构成了我所提出的良好心理健康的公共健康权的基础。
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引用次数: 0
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