首页 > 最新文献

人文科学最新文献

英文 中文
IF:
Self-serving beliefs about science: Science justifies my weaknesses (but not other people's). 自以为是的科学信仰:科学能证明我的弱点是合理的(但不能证明别人的弱点是合理的)。
IF 3.5 2区 文学 Q1 COMMUNICATION Pub Date : 2025-02-01 Epub Date: 2024-07-30 DOI: 10.1177/09636625241261320
Francisco Cruz, André Mata

This research explored the strategic beliefs that people have about science and the extent to which it can explain moral and immoral behaviors. Although people do not believe that science is able to explain certain aspects of their mind, they might nevertheless accept a scientific explanation for their immoral behaviors if that explanation is exculpatory. In a first study, participants reflected on moral and immoral deeds that they performed or that other people performed. Participants were somewhat skeptic that science can account for people's behavior-except for when they reflected on the wrongdoings that they committed. Two further studies suggest that strategic belief in science arises because it enables external attributions for the behavior, outside of the wrongdoers' control. Implications are discussed for science understanding and communication.

这项研究探讨了人们对科学的战略信念,以及科学能在多大程度上解释道德和不道德行为。尽管人们不相信科学能够解释他们思想的某些方面,但如果科学解释能够开脱他们的不道德行为,他们还是可能会接受这种解释。在第一项研究中,参与者对自己或他人的道德和不道德行为进行了反思。参与者对科学能否解释人们的行为持怀疑态度--但当他们反思自己所犯的错误行为时除外。另外两项研究表明,之所以会产生对科学的战略信念,是因为科学能够在外部对行为进行归因,而这是不法行为者无法控制的。本文讨论了对科学的理解和传播的影响。
{"title":"Self-serving beliefs about science: Science justifies my weaknesses (but not other people's).","authors":"Francisco Cruz, André Mata","doi":"10.1177/09636625241261320","DOIUrl":"10.1177/09636625241261320","url":null,"abstract":"<p><p>This research explored the strategic beliefs that people have about science and the extent to which it can explain moral and immoral behaviors. Although people do not believe that science is able to explain certain aspects of their mind, they might nevertheless accept a scientific explanation for their immoral behaviors if that explanation is exculpatory. In a first study, participants reflected on moral and immoral deeds that they performed or that other people performed. Participants were somewhat skeptic that science can account for people's behavior-<i>except</i> for when they reflected on the wrongdoings that they committed. Two further studies suggest that strategic belief in science arises because it enables external attributions for the behavior, outside of the wrongdoers' control. Implications are discussed for science understanding and communication.</p>","PeriodicalId":48094,"journal":{"name":"Public Understanding of Science","volume":" ","pages":"172-187"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"文学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction. 更正。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2025-02-01 Epub Date: 2024-04-11 DOI: 10.1080/08989621.2024.2334736
{"title":"Correction.","authors":"","doi":"10.1080/08989621.2024.2334736","DOIUrl":"10.1080/08989621.2024.2334736","url":null,"abstract":"","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"i"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy is inaccurate: Why a focus on diagnostic accuracy for medical chatbot AIs will not lead to improved health outcomes. 准确是不准确的:为什么关注医疗聊天机器人人工智能的诊断准确性不会带来更好的医疗效果?
IF 1.7 2区 哲学 Q2 ETHICS Pub Date : 2025-02-01 Epub Date: 2024-10-30 DOI: 10.1111/bioe.13365
Stephen R Milford

Since its launch in November 2022, ChatGPT has become a global phenomenon, sparking widespread public interest in chatbot artificial intelligences (AIs) generally. While not approved for medical use, it is capable of passing all three United States medical licensing exams and offers diagnostic accuracy comparable to a human doctor. It seems inevitable that it, and tools like it, are and will be used by the general public to provide medical diagnostic information or treatment plans. Before we are taken in by the promise of a golden age for chatbot medical AIs, it would be wise to consider the implications of using these tools as either supplements to, or substitutes for, human doctors. With the rise of publicly available chatbot AIs, there has been a keen focus on research into the diagnostic accuracy of these tools. This, however, has left a notable gap in our understanding of the implications for health outcomes of these tools. Diagnosis accuracy is only part of good health care. For example, crucial to positive health outcomes is the doctor-patient relationship. This paper challenges the recent focus on diagnostic accuracy by drawing attention to the causal relationship between doctor-patient relationships and health outcomes arguing that chatbot AIs may even hinder outcomes in numerous ways including subtracting the elements of perception and observation that are crucial to clinical consultations. The paper offers brief suggestions to improve chatbot medical AIs so as to positively impact health outcomes.

自 2022 年 11 月推出以来,ChatGPT 已成为一种全球现象,引发了公众对聊天机器人人工智能(AI)的广泛兴趣。虽然它未被批准用于医疗用途,但它能通过美国所有三项医疗执照考试,诊断准确率可与人类医生媲美。它和类似的工具似乎不可避免地会被大众用来提供医疗诊断信息或治疗方案。在我们被聊天机器人医疗人工智能黄金时代的承诺所迷惑之前,最好先考虑一下使用这些工具作为人类医生的补充或替代品的影响。随着可公开获取的聊天机器人人工智能的兴起,人们开始热衷于研究这些工具的诊断准确性。然而,我们对这些工具对健康结果的影响的理解还存在明显差距。诊断准确性只是良好医疗保健的一部分。例如,医患关系对积极的健康结果至关重要。本文挑战了最近对诊断准确性的关注,提请人们注意医患关系与健康结果之间的因果关系,认为聊天机器人人工智能甚至可能以多种方式阻碍健康结果,包括减少对临床咨询至关重要的感知和观察元素。本文提出了改进聊天机器人医疗人工智能的简要建议,以便对健康结果产生积极影响。
{"title":"Accuracy is inaccurate: Why a focus on diagnostic accuracy for medical chatbot AIs will not lead to improved health outcomes.","authors":"Stephen R Milford","doi":"10.1111/bioe.13365","DOIUrl":"10.1111/bioe.13365","url":null,"abstract":"<p><p>Since its launch in November 2022, ChatGPT has become a global phenomenon, sparking widespread public interest in chatbot artificial intelligences (AIs) generally. While not approved for medical use, it is capable of passing all three United States medical licensing exams and offers diagnostic accuracy comparable to a human doctor. It seems inevitable that it, and tools like it, are and will be used by the general public to provide medical diagnostic information or treatment plans. Before we are taken in by the promise of a golden age for chatbot medical AIs, it would be wise to consider the implications of using these tools as either supplements to, or substitutes for, human doctors. With the rise of publicly available chatbot AIs, there has been a keen focus on research into the diagnostic accuracy of these tools. This, however, has left a notable gap in our understanding of the implications for health outcomes of these tools. Diagnosis accuracy is only part of good health care. For example, crucial to positive health outcomes is the doctor-patient relationship. This paper challenges the recent focus on diagnostic accuracy by drawing attention to the causal relationship between doctor-patient relationships and health outcomes arguing that chatbot AIs may even hinder outcomes in numerous ways including subtracting the elements of perception and observation that are crucial to clinical consultations. The paper offers brief suggestions to improve chatbot medical AIs so as to positively impact health outcomes.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"163-169"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11754992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Doppelgängers and Lifespan Extension: What Matters? 数字二重身与寿命延长:什么才是关键?
IF 17 1区 哲学 Q1 ETHICS Pub Date : 2025-02-01 Epub Date: 2024-11-14 DOI: 10.1080/15265161.2024.2416133
Samuel Iglesias, Brian D Earp, Cristina Voinea, Sebastian Porsdam Mann, Anda Zahiu, Nancy S Jecker, Julian Savulescu

There is an ongoing debate about the ethics of research on lifespan extension: roughly, using medical technologies to extend biological human lives beyond the current "natural" limit of about 120 years. At the same time, there is an exploding interest in the use of artificial intelligence (AI) to create "digital twins" of persons, for example by fine-tuning large language models on data specific to particular individuals. In this paper, we consider whether digital twins (or digital doppelgängers, as we refer to them) could be a path toward a kind of life extension-or more precisely, a kind of person extension-that does not rely on biological continuity. We discuss relevant accounts of consciousness and personal identity and argue that digital doppelgängers may at least help us achieve some of the aims or ostensible goods of person-span extension, even if they may not count as literal extensions of our personhood on dominant philosophical accounts. We also consider relational accounts of personhood and discuss how digital doppelgängers may be able to extend personhood in a relational sense, or at least secure some of the goods associated with relevant relationships. We conclude by suggesting that a research program to investigate such issues is relevant to ongoing debates about the ethics of extending the human lifespan.

关于寿命延长研究的伦理问题一直存在争论:粗略地说,就是利用医疗技术将人类的生物寿命延长到目前的 "自然 "极限,即 120 岁左右。与此同时,人们对利用人工智能(AI)创建人的 "数字双胞胎 "的兴趣也日益高涨,例如通过微调特定个体数据的大型语言模型。在本文中,我们将考虑数字双胞胎(或我们所称的数字二重身)是否可以成为一种不依赖于生物连续性的生命延续--或者更准确地说,一种人的延续--的途径。我们讨论了意识和个人身份的相关论述,并认为数字二重身至少可以帮助我们实现人的寿命延长的某些目标或表面上的好处,即使它们在主流哲学论述中可能并不能算作我们人格的字面延伸。我们还考虑了人格的关系论,并讨论了数字二重身如何能够在关系意义上扩展人格,或至少确保一些与相关关系有关的益处。最后,我们提出,研究此类问题的研究计划与当前关于延长人类寿命的伦理问题的讨论息息相关。
{"title":"Digital Doppelgängers and Lifespan Extension: What Matters?","authors":"Samuel Iglesias, Brian D Earp, Cristina Voinea, Sebastian Porsdam Mann, Anda Zahiu, Nancy S Jecker, Julian Savulescu","doi":"10.1080/15265161.2024.2416133","DOIUrl":"10.1080/15265161.2024.2416133","url":null,"abstract":"<p><p>There is an ongoing debate about the ethics of research on lifespan extension: roughly, using medical technologies to extend biological human lives beyond the current \"natural\" limit of about 120 years. At the same time, there is an exploding interest in the use of artificial intelligence (AI) to create \"digital twins\" of persons, for example by fine-tuning large language models on data specific to particular individuals. In this paper, we consider whether digital twins (or digital doppelgängers, as we refer to them) could be a path toward a kind of life extension-or more precisely, a kind of <i>person</i> extension-that does not rely on biological continuity. We discuss relevant accounts of consciousness and personal identity and argue that digital doppelgängers may at least help us achieve some of the <i>aims</i> or ostensible goods of person-span extension, even if they may not count as literal extensions of our personhood on dominant philosophical accounts. We also consider <i>relational</i> accounts of personhood and discuss how digital doppelgängers may be able to extend personhood in a relational sense, or at least secure some of the goods associated with relevant relationships. We conclude by suggesting that a research program to investigate such issues is relevant to ongoing debates about the ethics of extending the human lifespan.</p>","PeriodicalId":50962,"journal":{"name":"American Journal of Bioethics","volume":" ","pages":"95-110"},"PeriodicalIF":17.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Worth the Risk?
IF 17 1区 哲学 Q1 ETHICS Pub Date : 2025-02-01 Epub Date: 2025-01-29 DOI: 10.1080/15265161.2024.2441750
Jason T Eberl
{"title":"Worth the Risk?","authors":"Jason T Eberl","doi":"10.1080/15265161.2024.2441750","DOIUrl":"https://doi.org/10.1080/15265161.2024.2441750","url":null,"abstract":"","PeriodicalId":50962,"journal":{"name":"American Journal of Bioethics","volume":"25 2","pages":"116-118"},"PeriodicalIF":17.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incorporating implicit bias into research integrity education: Response to 'Why and how to incorporate issues of race/ethnicity and gender in research integrity education'. 将隐性偏见纳入研究诚信教育:对“为什么以及如何将种族/民族和性别问题纳入研究诚信教育”的回应。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2025-02-01 Epub Date: 2023-08-21 DOI: 10.1080/08989621.2023.2247974
Shivatej Dubbaka

This letter focuses on the importance of incorporating implicit bias into research integrity education, and the significant impact it can have on creating an equitable research environment.

这封信的重点是将隐性偏见纳入研究诚信教育的重要性,以及它对创造公平的研究环境的重大影响。
{"title":"Incorporating implicit bias into research integrity education: Response to 'Why and how to incorporate issues of race/ethnicity and gender in research integrity education'.","authors":"Shivatej Dubbaka","doi":"10.1080/08989621.2023.2247974","DOIUrl":"10.1080/08989621.2023.2247974","url":null,"abstract":"<p><p>This letter focuses on the importance of incorporating implicit bias into research integrity education, and the significant impact it can have on creating an equitable research environment.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"193-194"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10030503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extent of publishing in predatory journals by academics in higher education institutions in Zimbabwe: A case study of a university. 津巴布韦高等教育机构的学者在掠夺性期刊上发表文章的程度:一所大学的案例研究。
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2025-02-01 Epub Date: 2023-09-11 DOI: 10.1080/08989621.2023.2256672
R M Jingura, J Chigwada, T Diver, D Shangwa

The publish or perish concept requires academics to ensure that they take part in research and publish the research results in academic journals. The emergency of predatory publishers has led to negativity in the scholarly publishing process. Some researchers are unaware that some publishers are unethical. A study was conducted to determine the extent of predatory publishing in Zimbabwe among academics. A survey was carried out using a multi-method approach at a public university in Zimbabwe. Articles published between 2012 and 2022 were retrieved using the Harzing publish or perish software. In total, 977 articles were retrieved, and after data cleaning using Open Refine, 357 records were analyzed using the journal evaluation rubric and scoring sheet to note the extent of predatory publishing among the various schools. The articles were then classified into 3 sections i.e., predatory, not predatory, and borderline. The findings revealed that predatory publishing is prevalent in the social sciences. The authors recommend the importance of training to create awareness about the dangers of predatory publishing and how to avoid them to improve the scholarly output of the institution, which is key to university ranking.

“要么发表,要么灭亡”的理念要求学者确保自己参与研究,并在学术期刊上发表研究成果。掠夺性出版商的出现给学术出版带来了负面影响。一些研究人员没有意识到一些出版商是不道德的。进行了一项研究,以确定津巴布韦学术界掠夺性出版的程度。在津巴布韦的一所公立大学采用多种方法进行了一项调查。2012年至2022年间发表的文章是通过Harzing发布或消亡软件检索的。总共检索了977篇文章,在使用Open Refine进行数据清理后,使用期刊评估标题和计分表分析了357条记录,以指出各学院掠夺性出版的程度。然后这些文章被分为3个部分,即掠夺性,非掠夺性和边缘性。调查结果显示,掠夺性出版在社会科学领域非常普遍。这组作者推荐了培训的重要性,以提高人们对掠夺性出版的危险的认识,以及如何避免这些危险以提高机构的学术产出,这是大学排名的关键。
{"title":"Extent of publishing in predatory journals by academics in higher education institutions in Zimbabwe: A case study of a university.","authors":"R M Jingura, J Chigwada, T Diver, D Shangwa","doi":"10.1080/08989621.2023.2256672","DOIUrl":"10.1080/08989621.2023.2256672","url":null,"abstract":"<p><p>The publish or perish concept requires academics to ensure that they take part in research and publish the research results in academic journals. The emergency of predatory publishers has led to negativity in the scholarly publishing process. Some researchers are unaware that some publishers are unethical. A study was conducted to determine the extent of predatory publishing in Zimbabwe among academics. A survey was carried out using a multi-method approach at a public university in Zimbabwe. Articles published between 2012 and 2022 were retrieved using the Harzing publish or perish software. In total, 977 articles were retrieved, and after data cleaning using Open Refine, 357 records were analyzed using the journal evaluation rubric and scoring sheet to note the extent of predatory publishing among the various schools. The articles were then classified into 3 sections i.e., predatory, not predatory, and borderline. The findings revealed that predatory publishing is prevalent in the social sciences. The authors recommend the importance of training to create awareness about the dangers of predatory publishing and how to avoid them to improve the scholarly output of the institution, which is key to university ranking.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"143-157"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10205928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Are there accurate and legitimate ways to machine-quantify predatoriness, or an urgent need for an automated online tool? 是否有准确和合法的方法来机器量化掠夺性,或者迫切需要一个自动化的在线工具?
IF 2.8 1区 哲学 Q1 MEDICAL ETHICS Pub Date : 2025-02-01 Epub Date: 2023-08-31 DOI: 10.1080/08989621.2023.2253425
Bor Luen Tang

Yamada and Teixeira da Silva voiced valid concerns with the inadequacies of an online machine learning-based tool to detect predatory journals, and stressed on the urgent need for an automated, open, online-based semi-quantitative system that measures "predatoriness". We agree that the said machine learning-based tool lacks accuracy in its demarcation and identification of journals outside those already found within existing black and white lists, and that its use could have undesirable impact on the community. We note further that the key characteristic of journals being predatory, namely a lack of stringent peer review, would normally not have the visibility necessary for training and informing machine learning-based online tools. This, together with the gray zone of inadequate scholarly practice and the plurality in authors' perception of predatoriness, makes it desirable for any machine-based, quantitative assessment to be complemented or moderated by a community-based, qualitative assessment that would do more justice to both journals and authors.

Yamada和Teixeira da Silva对一种基于在线机器学习的工具在检测掠夺性期刊方面的不足表示了合理的担忧,并强调迫切需要一种自动化、开放、基于在线的半定量系统来衡量“掠夺性”。我们同意上述基于机器学习的工具在划分和识别现有黑白名单之外的期刊方面缺乏准确性,并且它的使用可能会对社区产生不良影响。我们进一步注意到,期刊掠夺性的关键特征,即缺乏严格的同行评议,通常不具备培训和通知基于机器学习的在线工具所必需的可见性。这一点,再加上学术实践不足的灰色地带和作者对掠夺性看法的多样性,使得任何基于机器的定量评估都需要由基于社区的定性评估来补充或缓和,这将对期刊和作者都更加公正。
{"title":"Are there accurate and legitimate ways to machine-quantify predatoriness, or an urgent need for an automated online tool?","authors":"Bor Luen Tang","doi":"10.1080/08989621.2023.2253425","DOIUrl":"10.1080/08989621.2023.2253425","url":null,"abstract":"<p><p>Yamada and Teixeira da Silva voiced valid concerns with the inadequacies of an online machine learning-based tool to detect predatory journals, and stressed on the urgent need for an automated, open, online-based semi-quantitative system that measures \"predatoriness\". We agree that the said machine learning-based tool lacks accuracy in its demarcation and identification of journals outside those already found within existing black and white lists, and that its use could have undesirable impact on the community. We note further that the key characteristic of journals being predatory, namely a lack of stringent peer review, would normally not have the visibility necessary for training and informing machine learning-based online tools. This, together with the gray zone of inadequate scholarly practice and the plurality in authors' perception of predatoriness, makes it desirable for any machine-based, quantitative assessment to be complemented or moderated by a community-based, qualitative assessment that would do more justice to both journals and authors.</p>","PeriodicalId":50927,"journal":{"name":"Accountability in Research-Policies and Quality Assurance","volume":" ","pages":"182-187"},"PeriodicalIF":2.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10474862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical research vehicles as a modality for medical research education and conduct of decentralized trials, supporting justice, equity, and diversity in research. 临床研究车作为医学研究教育和开展分散试验的一种模式,支持研究的公正、公平和多样性。
IF 1.7 2区 哲学 Q2 ETHICS Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.1111/bioe.13360
Kenneth T Moore

Current clinical research lacks diversity in those that participate. This lack of diversity is concerning given its importance for successful drug development. The frequency and severity of many diseases, along with the pharmacological properties of therapies, can display significant differences based on patient diversity. A clinical trial population that is more reflective of these differences will help researchers better understand the therapeutic profile of the treatment and provide generalizable knowledge to the medical community. The advent of decentralized clinical trial designs is meant to help address this lack of diversity by using portable digital health technologies and virtual interactions to enhance clinical trial access and broaden participation. By leveraging these technologies, trial conduct can occur at locations other than traditional research sites. This shift in trial location may help address some of the logistical, educational, engagement, and trust barriers that have historically prevented enrollment of diverse populations. However, these types of trials still have limitations. Ethical concerns around justice, equity, and diversity will still exist with decentralized clinical trials, which could be mediated using clinical research vehicles. When utilized, this modality may enhance the scientific design and conduct of clinical trials and better follow these ethical principles. These enhancements and improved ethical direction could be accomplished through increasing community involvement, improving health literacy, supporting more diverse trial sites, creating community-based research footholds, fostering connections with researchers, limiting technical challenges, and preventing data security issues.

目前的临床研究缺乏参与人员的多样性。这种缺乏多样性的现象令人担忧,因为它对药物的成功开发非常重要。许多疾病的发病率和严重程度,以及疗法的药理特性,都会因患者的多样性而产生显著差异。更能反映这些差异的临床试验人群将有助于研究人员更好地了解治疗方法的治疗概况,并为医学界提供可推广的知识。分散式临床试验设计的出现旨在利用便携式数字医疗技术和虚拟互动来提高临床试验的可及性和扩大参与范围,从而帮助解决缺乏多样性的问题。利用这些技术,试验可以在传统研究地点以外的地点进行。这种试验地点的转变可能有助于解决一些后勤、教育、参与和信任方面的障碍,这些障碍在历史上一直阻碍着不同人群的参与。然而,这类试验仍有局限性。分散式临床试验仍会存在公正、公平和多样性方面的伦理问题,这可以通过临床研究工具来解决。利用这种方式,可以加强临床试验的科学设计和实施,更好地遵循这些伦理原则。可以通过增加社区参与、提高健康知识普及率、支持更多样化的试验场地、创建基于社区的研究立足点、促进与研究人员的联系、限制技术挑战以及预防数据安全问题来实现这些改进和改善伦理方向。
{"title":"Clinical research vehicles as a modality for medical research education and conduct of decentralized trials, supporting justice, equity, and diversity in research.","authors":"Kenneth T Moore","doi":"10.1111/bioe.13360","DOIUrl":"10.1111/bioe.13360","url":null,"abstract":"<p><p>Current clinical research lacks diversity in those that participate. This lack of diversity is concerning given its importance for successful drug development. The frequency and severity of many diseases, along with the pharmacological properties of therapies, can display significant differences based on patient diversity. A clinical trial population that is more reflective of these differences will help researchers better understand the therapeutic profile of the treatment and provide generalizable knowledge to the medical community. The advent of decentralized clinical trial designs is meant to help address this lack of diversity by using portable digital health technologies and virtual interactions to enhance clinical trial access and broaden participation. By leveraging these technologies, trial conduct can occur at locations other than traditional research sites. This shift in trial location may help address some of the logistical, educational, engagement, and trust barriers that have historically prevented enrollment of diverse populations. However, these types of trials still have limitations. Ethical concerns around justice, equity, and diversity will still exist with decentralized clinical trials, which could be mediated using clinical research vehicles. When utilized, this modality may enhance the scientific design and conduct of clinical trials and better follow these ethical principles. These enhancements and improved ethical direction could be accomplished through increasing community involvement, improving health literacy, supporting more diverse trial sites, creating community-based research footholds, fostering connections with researchers, limiting technical challenges, and preventing data security issues.</p>","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"213-220"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family-making avec emerging technologies and/or non-human animals. 与新兴技术和/或非人类动物建立家庭。
IF 1.7 2区 哲学 Q2 ETHICS Pub Date : 2025-02-01 Epub Date: 2024-11-10 DOI: 10.1111/bioe.13371
Niñoval F Pacaol, Alderf Anthonio T Cabero, Britten Izzy A Ragonot, Alysha Mae A Cajes, Princess Zuemaeyah J Sarsalejo, Ybrahim Jamil B Monge, Jacob Razel D Villaluz, Abishai Andea A Adorna
{"title":"Family-making avec emerging technologies and/or non-human animals.","authors":"Niñoval F Pacaol, Alderf Anthonio T Cabero, Britten Izzy A Ragonot, Alysha Mae A Cajes, Princess Zuemaeyah J Sarsalejo, Ybrahim Jamil B Monge, Jacob Razel D Villaluz, Abishai Andea A Adorna","doi":"10.1111/bioe.13371","DOIUrl":"10.1111/bioe.13371","url":null,"abstract":"","PeriodicalId":55379,"journal":{"name":"Bioethics","volume":" ","pages":"226-227"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
全部 PHYS PERSPECT American Antiquity Antiquity Ann. Sci. Aust. Archaeol. Biling (Camb Engl) Business History Review Comunicar Digital Journalism Games and Culture Indogermanische Forschungen Intercultural Pragmatics Int. J. Osteoarchaeol. International Labor and Working-Class History ISIS J MED ETHICS Journal of Modern Italian Studies Journal of Pragmatics Journalism Studies Language Testing Language, Culture and Curriculum Language Law and History Review MED HIST Media and Communication Media, Culture & Society Mediterranean Historical Review Mod Italy NANOETHICS Natural Language & Linguistic Theory New Media & Society Social Semiotics SOC HIST MED Studies in Second Language Acquisition World Englishes Language Context and Text-The Social Semiotics Forum Psychology of Popular Media Transactions of the Association for Computational Linguistics Gesture (Amst) Language Testing in Asia Acta Linguistica Academica International Journal of Chinese Linguistics Journal of Modern Chinese History International Journal of Chinese & Comparative Philosophy of Medicine Dialectologia et Geolinguistica Africana Linguistica Language & History Zeitgeschichte Frontiers of History in China Dutch Crossing-Journal of Low Countries Studies Tijdschrift Voor Communicatiewetenschap Etikk I Praksis Zeitschrift Fur Dialektologie Und Linguistik Vigo Int J Appl Linguist Global Media and China Scandia Tydskrif Vir Geesteswetenskappe Estudios Filologicos Journal of Germanic Linguistics Studies in East European Thought Nordic Journal of Linguistics Journal of African Languages and Linguistics J Isr Hist Journal of Comparative Germanic Linguistics Zeitschrift Fur Sprachwissenschaft Journal of the Gilded Age and Progressive Era Journal of Pidgin and Creole Languages French History War & Society Journal of African Media Studies Poznan Studies in Contemporary Linguistics European Journal of English Studies International Journal of Speech Language and the Law Translation and Interpreting Studies Language Matters Lond J Linguistica Antverpiensia New Series-Themes in Translation Studies Lexikos J Vic Cult Journal of French Language Studies Pragmatics and Society Oral Hist Rev Labour History Across Languages and Cultures Revista De Historia Industrial Functions of Language Rilce-Revista De Filologia Hispanica Names-A Journal of Onomastics J Mod Eur Hist Rural History-Economy Society Culture Language Problems & Language Planning Praehistorische Zeitschrift Journal of Early Modern History Terminology Spanish in Context Babel-Revue Internationale De La Traduction-International Journal of Translation Circulo De Linguistica Aplicada a La Comunicacion Ger Hist Itinerario Imago Mundi
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1