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Uncertainty-aware human-machine collaboration in Camouflaged Object Detection. 伪装目标检测中的不确定性感知人机协作。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2026-02-03 DOI: 10.1007/s11571-025-10407-x
Ziyue Yang, Kehan Wang, Yuhang Ming, Han Yang, Qiong Chen, Yong Peng, Wanzeng Kong

Camouflaged Object Detection (COD), the task of identifying objects concealed within their environments, has seen rapid growth due to its wide range of practical applications. We propose a human-machine collaboration framework for COD, leveraging the complementary strengths of computer vision (CV) models and noninvasive brain-computer interfaces (BCIs). Our approach introduces a multiview backbone to estimate uncertainty in CV predictions, utilizes this uncertainty during training to improve efficiency, and defers low-confidence cases to human evaluation via RSVP-based BCIs during testing for more reliable decision-making. Evaluated on the CAMO dataset, our framework achieves state-of-the-art results with an average improvement of 4.56% in balanced accuracy (BA) and 3.66% in the F1 score. For the best-performing participants, improvements reached 7.6% in BA and 6.66% in the F1 score. Training analysis showed a strong correlation between confidence and precision, while ablation studies confirmed the effectiveness of our training policy and human-machine collaboration strategy. This work reduces human cognitive load, improves system reliability, and provides a foundation for advancements in real-world COD applications and human-computer interaction. Our code and data are available at: https://github.com/ziyuey/Uncertainty-aware-human-machine-collaboration-in-camouflaged-object-identification.

伪装目标检测(COD)是一项识别隐藏在其环境中的目标的任务,由于其广泛的实际应用而迅速发展。利用计算机视觉(CV)模型和无创脑机接口(bci)的互补优势,我们提出了一个COD的人机协作框架。我们的方法引入了一个多视图主干来估计CV预测中的不确定性,在训练过程中利用这种不确定性来提高效率,并在测试过程中通过基于rsvp的bci将低置信度案例推迟给人类评估,以获得更可靠的决策。在CAMO数据集上进行评估,我们的框架达到了最先进的结果,平衡精度(BA)平均提高4.56%,F1分数平均提高3.66%。对于表现最好的参与者,BA成绩提高了7.6%,F1成绩提高了6.66%。训练分析显示置信度和精确度之间有很强的相关性,而消融研究证实了我们的训练政策和人机协作策略的有效性。这项工作减少了人类的认知负荷,提高了系统可靠性,并为现实世界COD应用和人机交互的进步提供了基础。我们的代码和数据可在:https://github.com/ziyuey/Uncertainty-aware-human-machine-collaboration-in-camouflaged-object-identification。
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引用次数: 0
Automated differentiation of parkinsonian disorders: an ROI-based analysis of subcortical shape and cortical surface features. 帕金森病的自动分化:基于roi的皮层下形状和皮层表面特征分析。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2026-02-03 DOI: 10.1007/s11571-025-10402-2
Yousef Dehghan, Yashar Sarbaz

The clinical manifestations of early-stage parkinsonian syndromes overlap, making accurate differential diagnosis crucial yet challenging. This study aimed to develop a system for automated differentiation of idiopathic Parkinson's disease (IPD) from progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS). Our sample included clinical data and T1-weighted magnetic resonance imaging from 50 IPD, 47 PSP, and 38 CBS patients. We introduced an atlas-based approach to extract shape features from subcortical regions in each subject's native coordinate image space. The surface thickness and folding parameters were also extracted from cortical regions. A statistical analysis was conducted to identify regions with significant differences in the extracted features, followed by the employment of a feed-forward neural network to distinguish these patients. Significant structural differences were observed in several regions, including the thalamic nuclei, basal ganglia, midbrain, cerebellum, cingulate cortex, and insula. Using only cortical surface features, our diagnostic model outperformed the model that relied solely on subcortical shape features. However, the classifier achieved its best predictive performance when incorporating features from both cortical and subcortical structures, yielding an accuracy of 86.1% in a multi-class classification system and 96.1% for distinguishing IPD from PSP and CBS, as well as an accuracy of 94.2% for classifying CBS versus PSP in a two-class classification system. Our findings underscore the significance of cortical morphological patterns and demonstrate that the proposed methodology could potentially serve as an automated diagnostic system in clinical settings.

Supplementary information: The online version contains supplementary material available at 10.1007/s11571-025-10402-2.

早期帕金森综合征的临床表现重叠,使准确的鉴别诊断至关重要,但具有挑战性。本研究旨在开发一种用于特发性帕金森病(IPD)与进行性核上性麻痹(PSP)和皮质基底综合征(CBS)自动鉴别的系统。我们的样本包括50例IPD、47例PSP和38例CBS患者的临床资料和t1加权磁共振成像。我们引入了一种基于地图集的方法,从每个受试者的原生坐标图像空间的皮质下区域提取形状特征。提取皮层区域的表面厚度和折叠参数。通过统计分析来识别提取的特征中存在显著差异的区域,然后使用前馈神经网络来区分这些患者。在丘脑核、基底节区、中脑、小脑、扣带皮层和脑岛等几个区域观察到显著的结构差异。仅使用皮质表面特征,我们的诊断模型优于仅依赖皮质下形状特征的模型。然而,当结合皮层和皮层下结构的特征时,分类器获得了最佳的预测性能,在多类分类系统中准确率为86.1%,区分IPD与PSP和CBS的准确率为96.1%,在两类分类系统中区分CBS与PSP的准确率为94.2%。我们的研究结果强调了皮层形态模式的重要性,并证明了所提出的方法可以潜在地作为临床设置的自动诊断系统。补充信息:在线版本包含补充资料,提供地址为10.1007/s11571-025-10402-2。
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引用次数: 0
A neuro-inspired visual SLAM approach using AKAZE feature extraction in complex and dynamic environments. 在复杂和动态环境中使用AKAZE特征提取的神经启发的视觉SLAM方法。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2025-12-06 DOI: 10.1007/s11571-025-10386-z
Ruibang Li, Yihong Wang, Xuying Xu, Fangfei Li, Fengzhen Tang, Xiaochuan Pan

Place cells and head direction cells in the rodent brain encode spatial position and orientation, forming the neural basis for navigation and cognitive map construction. Inspired by these mechanisms, RatSLAM simulates their roles to achieve biologically inspired visual SLAM. However, traditional RatSLAM struggles with robust feature extraction in visually complex or dynamic environments, where features may be unstable or non-distinct. To address this, we integrate the AKAZE algorithm into the RatSLAM framework. AKAZE combines accelerated techniques with nonlinear diffusion filtering to construct a multi-scale nonlinear scale space, enabling efficient extraction of robust, scale-invariant features across spatial scales. These features are incorporated into RatSLAM's local view module to improve loop closure detection and mitigate odometry drift. Traditional evaluation approaches rely on real-time pose trajectories and cannot evaluate the trajectories based on the fully optimized experience maps, leading to inaccurate mapping performance assessments. Thus, we further propose a novel Ray-Based Map Metric Error Evaluation Method, which can directly compare the final experience maps generated by RatSLAM. Experiments on the KITTI dataset demonstrate that, compared with both ORB-RatSLAM and the ORB-SLAM3, the proposed AKAZE-RatSLAM achieves higher loop closure recall and mapping accuracy while maintaining a lightweight computational profile. In particular, CPU and memory measurements show that AKAZE-RatSLAM requires significantly less computational resources than ORB-SLAM3, confirming its suitability for real-time deployment on resource-limited robotic platforms. Furthermore, neuro-inspired analyses reveal that the pose cell network exhibits spatially localized and direction-selective firing patterns analogous to hippocampal place cells and head direction cells in rodents. Specifically, cells along the same row encode adjacent spatial regions, forming continuous place-field-like activations, whereas cells in the same column show distinct preferred orientations, indicating directional tuning. These biological characteristics confirm that the proposed AKAZE-RatSLAM not only enhances mapping performance and efficiency but also preserves the neurobiological plausibility of spatial representation, advancing the development of brain-inspired visual SLAM systems.

鼠脑中的位置细胞和头部方向细胞编码空间位置和方向,形成导航和认知地图构建的神经基础。受这些机制的启发,RatSLAM模拟了它们的作用,以实现生物学启发的视觉SLAM。然而,传统的RatSLAM在视觉复杂或动态环境中难以进行鲁棒特征提取,因为这些环境中的特征可能不稳定或不明显。为了解决这个问题,我们将AKAZE算法集成到RatSLAM框架中。AKAZE将加速技术与非线性扩散滤波相结合,构建了一个多尺度非线性尺度空间,能够有效地提取跨空间尺度的鲁棒、尺度不变特征。这些功能被整合到RatSLAM的本地视图模块中,以改进环路关闭检测并减轻里程计漂移。传统的评估方法依赖于实时姿态轨迹,无法基于完全优化的经验图对轨迹进行评估,导致映射性能评估不准确。因此,我们进一步提出了一种新的基于光线的地图度量误差评估方法,该方法可以直接比较RatSLAM生成的最终体验地图。在KITTI数据集上的实验表明,与ORB-RatSLAM和ORB-SLAM3相比,AKAZE-RatSLAM在保持轻量级计算轮廓的同时,实现了更高的环路闭合召回率和映射精度。特别是,CPU和内存测量表明,AKAZE-RatSLAM所需的计算资源比ORB-SLAM3要少得多,这证实了它适合在资源有限的机器人平台上实时部署。此外,神经启发的分析表明,姿势细胞网络表现出空间定位和方向选择的放电模式,类似于啮齿动物的海马位置细胞和头部方向细胞。具体来说,沿着同一行的细胞编码相邻的空间区域,形成连续的位置场激活,而同一列的细胞显示出不同的首选方向,表明定向调谐。这些生物学特征证实,AKAZE-RatSLAM不仅提高了制图性能和效率,而且保留了空间表征的神经生物学合理性,促进了脑启发视觉SLAM系统的发展。
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引用次数: 0
Tremor estimation and filtering in robotic-assisted surgery. 机器人辅助手术中的震颤估计与滤波。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2025-12-06 DOI: 10.1007/s11571-025-10387-y
Boqiang Jia, Wenjie Wang, Xin Tian, Xiaohua Wang

In surgical procedures, surgeons can suffer from spontaneous hand tremors that can affect the accuracy of surgical robots. Therefore, it is necessary to measure and model the tremor signal by sensors to suppress hand tremor. This paper proposes a prediction method based on deep learning that integrates long-term and short-term features to achieve this goal. The long-term features of tremor signals are extracted using a bidirectional Long-short-term memory network, while the short-term features are extracted using a Temporal Convolutional Network. By integrating the long-term and short-term characteristics of tremor signals, this approach provides rich temporal information for signal estimation. In addition, genetic algorithm is used to obtain the optimal time step-size to fully explore the temporal correlation of signals, and an end data compensation strategy is adopted to ensure that the tremor filtering covers the entire process. The performance of the proposed method is evaluated by training and testing on the same dataset as other methods, and conducting suture experiments in a virtual surgical environment. The results show that our proposed model is superior to the existing methods, effectively reducing the tremor signals estimation error. This method can provide better tremor estimation and compensation performance, effectively suppressing the hand tremors and improving the surgical accuracy.

在外科手术过程中,外科医生可能会遭受自发的手部震颤,这可能会影响手术机器人的准确性。因此,有必要利用传感器对震颤信号进行测量和建模,以抑制手部震颤。本文提出了一种基于深度学习的长期和短期特征相结合的预测方法来实现这一目标。采用双向长短期记忆网络提取震颤信号的长期特征,采用时间卷积网络提取震颤信号的短期特征。该方法综合了地震信号的长期和短期特征,为地震信号估计提供了丰富的时间信息。此外,采用遗传算法获取最优时间步长,充分挖掘信号的时间相关性,并采用末端数据补偿策略,确保震颤滤波覆盖整个过程。通过在与其他方法相同的数据集上进行训练和测试,以及在虚拟手术环境中进行缝合实验,评估了所提出方法的性能。结果表明,该模型优于现有方法,有效地降低了地震信号的估计误差。该方法能提供较好的震颤估计和补偿性能,有效地抑制手部震颤,提高手术精度。
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引用次数: 0
SC-SDT: a framework with spectral convolution and spatial differential transformer for EEG-based emotion recognition. 基于频谱卷积和空间差分变压器的基于脑电图的情感识别框架。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2025-12-26 DOI: 10.1007/s11571-025-10394-z
Qiang Li, Jiajin Huang, Haiyan Zhou

EEG signals are widely used in emotion recognition due to their capability for objective emotional state quantification. However, despite containing abundant frequency and spatial information, researchers continue to face challenges in extracting fine-grained discriminative features from these signals. We develop SC-SDT (Spectral Convolution-Spatial Differential Transformer), a novel framework that jointly models spectral and spatial characteristics through an integrated convolutional and transformer architecture. First the model is equipped with a Spectral Feature Embedding module that employs a sequential group-pointwise convolutional network. This enables the dynamic capture of both local spectral patterns within bands and global interactions across the frequency spectrum. Subsequently, a Spatial Feature Extraction module is designed to simultaneously mitigate attention noise and optimize functional connectivity mapping across EEG channels through its core differential attention mechanism. Finally, to enhance model robustness against inter-subject variability, we introduce supervised contrastive loss that explicitly enforces subject-invariant feature representations while preserving class discriminability. Employing a subject-independent experimental paradigm, we rigorously evaluated the proposed SC-SDT model on SEED, SEED-IV, and DEAP datasets to assess cross-subject generalization capabilities. Experimental results demonstrate that SC-SDT achieves competitive emotion classification performance by effectively modeling spectral-spatial neural signatures. Our analysis of its key components further reveals that the model not only pioneers the application of differential attention in EEG, but also offers a methodological foundation for efficient spectral-spatial feature extraction. The code for this paper is accessible at https://github.com/apolloCoder-byte/SC-SDT.

由于脑电图信号具有客观量化情绪状态的能力,因此在情绪识别中得到了广泛的应用。然而,尽管含有丰富的频率和空间信息,研究人员仍然面临着从这些信号中提取细粒度判别特征的挑战。我们开发了SC-SDT(频谱卷积-空间差分变压器),这是一个通过集成卷积和变压器架构联合建模频谱和空间特征的新框架。首先,该模型配备了频谱特征嵌入模块,该模块采用顺序群点卷积网络。这使得可以动态捕获频带内的局部频谱模式和跨频谱的全局相互作用。随后,设计了空间特征提取模块,通过其核心的差分注意机制,在降低注意噪声的同时,优化脑电通道间的功能连接映射。最后,为了增强模型对主体间可变性的鲁棒性,我们引入了监督对比损失,该损失显式地强制主体不变特征表示,同时保持类的可辨别性。采用独立于学科的实验范式,我们在SEED、SEED- iv和DEAP数据集上严格评估了所提出的SC-SDT模型,以评估跨学科的泛化能力。实验结果表明,SC-SDT通过对频谱空间神经特征的有效建模,实现了竞争情绪的分类效果。通过对其关键组成部分的分析,进一步表明该模型不仅开创了差分注意在脑电图中的应用,而且为高效的频谱空间特征提取提供了方法基础。本文的代码可从https://github.com/apolloCoder-byte/SC-SDT访问。
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引用次数: 0
Does learning a second or third language affect the adaptation of cognitive control in multilinguals? A longitudinal fMRI study. 学习第二或第三语言是否影响多语言认知控制的适应?纵向功能磁共振成像研究。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2025-12-26 DOI: 10.1007/s11571-025-10397-w
Zehui Xing, Xiyuan Wang, Junjun Huang, John W Schwieter, Huanhuan Liu

Numerous studies in the bilingual literature have shown that cognitive control adapts to several factors related to second language (L2) learning. However, whether third language (L3) learning influences cognitive control remains underexplored. In this longitudinal study, we analyzed behavioral performance and functional magnetic resonance imaging (fMRI) data among Chinese-English bilinguals at resting-state and during a flanker task both prior to English (L2) or Japanese (L3) learning and one year later. During brain resting-states for these same learners, we conducted a correlation analysis between language exam scores and functional connectivity strength of resting-state data after one year of study. The connectivity between the left anterior cingulate cortex (ACC) and the left precuneus was positively correlated with English listening performance, while the connectivity between the right supramarginal gyrus (SMG) and the right inferior parietal lobe (IPL) was negatively correlated with English oral performance. The behavioral results from the flanker task showed that after one year of L2 learning in a classroom setting, a significantly smaller flanker effect emerged among Chinese-English bilinguals. Moreover, brain imaging revealed that incongruent flanker trials elicited greater activation of the left superior frontal gyrus (SFG) than congruent trials. These behavioral and neural patterns were not found among Chinese-English bilinguals who had studied Japanese for one year. Taken together, these findings suggest that cognitive control adapts to L2 learning, but appears to be unaffected by L3 learning.

Supplementary information: The online version contains supplementary material available at 10.1007/s11571-025-10397-w.

双语文献中的大量研究表明,认知控制适应与第二语言学习有关的几个因素。然而,第三语言(L3)学习是否影响认知控制仍未得到充分研究。在这项纵向研究中,我们分析了中英双语者在学习英语(L2)或日语(L3)之前和一年后的静息状态和侧背任务中的行为表现和功能磁共振成像(fMRI)数据。在这些学习者的大脑静息状态下,经过一年的学习,我们对语言考试成绩与静息状态数据的功能连接强度进行了相关性分析。左侧前扣带皮层(ACC)与左侧楔前叶之间的连通性与英语听力表现呈正相关,而右侧边缘上回(SMG)与右侧下顶叶(IPL)之间的连通性与英语口语表现呈负相关。侧卫任务的行为结果表明,在课堂环境下学习一年后,中英双语者的侧卫效应明显减弱。此外,脑成像显示,不一致的侧翼试验比一致的试验激发了更大的左侧额上回(SFG)的激活。这些行为和神经模式在学习日语一年的中英双语者中没有发现。综上所述,这些发现表明认知控制适应第二语言学习,但似乎不受第三语言学习的影响。补充信息:在线版本包含补充资料,提供地址:10.1007/s11571-025-10397-w。
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引用次数: 0
Control analysis of deep brain stimulation and optogenetics for Alzheimer's disease under the computational cortex model. 计算皮层模型下脑深部刺激和光遗传学治疗阿尔茨海默病的对照分析。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2025-11-24 DOI: 10.1007/s11571-025-10373-4
Ya Zhang, Honghui Zhang, Zhuan Shen

Abnormal τ and β-amyloid (Aβ) deposition in the brains of patients with Alzheimer's disease (AD) is significantly associated with cognitive decline. This abnormal deposition has been reported to be linked to increased excitatory and inhibitory time constants in neural circuits. In this paper, we focus on three typical electroencephalography (EEG) slowdowns clinically reported in association with AD, including decreased dominant frequency, decreased α rhythmic activity, and increased δ + θ rhythmic activity. Firstly, we demonstrate that changes in excitatory time constant, inhibitory time constants, and synaptic connection strength can induce the phenomenon of EEG slowdowns in early AD. Then, we are interested in the regulation of AD by traditional deep brain stimulation (DBS) and emerging optogenetic stimulation. High-frequency, high-pulse width, and high-amplitude DBS are more effective in reversing brain rhythm in AD, supporting the experiment that cortical high-frequency DBS may be an effective therapeutic way for dementia-related diseases. In particular, as a modification of traditional DBS, we find that oscillatory bursty stimulation can compensate for the shortcomings of DBS at low amplitude. However, it is physiologically difficult to target inhibitory interneurons with conventional electrical stimulation. Optogenetics is able to precisely stimulate pyramidal neurons and inhibitory interneurons observed in animal experiments. Our numerical results indicate that medium and low-frequency stimulation can better eliminate AD pathology. It should be noted that stimulation of inhibitory interneurons requires greater light intensity than stimulation of pyramidal neurons. Finally, we propose two optimization intermittent optogenetic stimulation protocols. These modeling results can reproduce some experimental phenomena and are expected to reveal the underlying pathological mechanisms and control strategies associated with cognitive dysfunction such as AD.

阿尔茨海默病(AD)患者大脑中异常τ和β-淀粉样蛋白(Aβ)沉积与认知能力下降显著相关。据报道,这种异常沉积与神经回路中兴奋性和抑制性时间常数增加有关。在本文中,我们重点研究了临床上报道的与AD相关的三种典型脑电图(EEG)减慢,包括显性频率降低、α节律活动降低和δ + θ节律活动增加。首先,我们证明了兴奋时间常数、抑制时间常数和突触连接强度的变化可以诱导早期AD的脑电图减慢现象。然后,我们对传统的深部脑刺激(DBS)和新兴的光遗传刺激对AD的调控感兴趣。高频、高脉宽和高振幅DBS在AD患者脑节律逆转方面更为有效,支持皮质高频DBS可能是痴呆相关疾病有效治疗方式的实验。特别是,作为传统DBS的改进,我们发现振荡脉冲刺激可以弥补DBS在低振幅下的缺点。然而,常规电刺激在生理上难以靶向抑制性中间神经元。光遗传学能够精确刺激动物实验中观察到的锥体神经元和抑制性中间神经元。我们的数值结果表明,中低频刺激能更好地消除AD病理。应该注意的是,刺激抑制性中间神经元比刺激锥体神经元需要更大的光强度。最后,我们提出了两种优化的间歇光遗传刺激方案。这些建模结果可以再现一些实验现象,并有望揭示与认知功能障碍(如AD)相关的潜在病理机制和控制策略。
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引用次数: 0
Design of intelligent neuro-supervised deep learning networks to analyze brain electrical activity rhythms of Parkinson's disease model. 设计智能神经监督深度学习网络分析帕金森病模型的脑电活动节律。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2026-02-03 DOI: 10.1007/s11571-025-10404-0
Sana Ullah Saqib, Shih-Hau Fang, Muhammad Asif Zahoor Raja, Kottakkaran Sooppy Nisar, Muhammad Shoaib
<p><p>Parkinson's disease (PD) is a multidimensional neurological condition designated by dopamine-sensitive neuron decline, which impairs generator and cognitive function. To study the dynamics of Parkinson's disease (PD), this paper presents a novel methodology that uses Intelligent Systems Neuro-Supervised Deep Learning Networks (INSDLNs). To describe the patterns of electrical activity in the brain metrics throughout various points in the central nervous system, we suggest a model based on mathematics governed by three distinct classes. To gain a deeper understanding of the fundamental processes underlying Parkinson's disease development, we aim to identify obscure trends within neurological data by leveraging intelligent neuro-supervised learning networks. This novel approach may lead to improved diagnostic and therapeutic approaches and holds promise for improving our understanding of the dynamics of Parkinson's disease (PD). By utilizing the features of an architecture containing multilayer recurrent layers, the suggested Intelligent Systems Neuro-Supervised Deep Learning Networks (INSDLNs) are designed. The input and target samples for INSDLNs were organizedand constructed from reference data that was formulated using the Adams method on a range of PI scenarios for modeling using a reliable numerical solver. To evaluate the impact on patterns of brain electrical activity, this method involved moving sensor positions.The differential equations are used for creating the dataset using Mathematica's ND solve function. The dataset for INSDLNs training was generated using the Adam stochastic solver. After that, this dataset is divided into three significant states: 80% is used for training, 10% is used for validation, and 15% is used for testing. The goal of these divisions is to effectively handle the difficulties presented by the dynamical model. The datasets, randomly divided into training, testing, and validation samples, were used to apply the INSDLNs created for the study. To ensure the model's stability and efficacy on various data sets, the procedure for segmentation was executed by optimizing a fitness function based on mean squared error. The proposed INSDLNs demonstrate accuracy, preciseness, and security through the achievement of minimal mean squared error (MSE), complete regression analysis (Rg. As), optimized error histograms (Err. Hg), auto-correlation of error (AC of Err), cross-correlation of input with error (CCIEr), and minimal absolute error (Ab. Er).When modeling the brain rhythms of Parkinson's disease, our INSDLNs outperformed LMBPA and BRM with very low error (MSE: 5.86E-12 ± 2.1E-12), nearly zero absolute error, and strong regression accuracy (R2 ≈ 0.998).A lower mean square error (MSE) shows that the suggested approach operates effectively and that the forecasts generated by the model are more reliable. Reaching an almost zero absolute error (Ab. Er) provides more evidence for INSDLNs. These results highlight the high
帕金森病(PD)是一种以多巴胺敏感神经元衰退为特征的多维神经系统疾病,其产生和认知功能受到损害。为了研究帕金森病(PD)的动力学,本文提出了一种使用智能系统神经监督深度学习网络(insdln)的新方法。为了描述贯穿中枢神经系统各个点的脑电活动模式,我们提出了一个基于数学的模型,该模型由三个不同的类别控制。为了更深入地了解帕金森病发展的基本过程,我们的目标是利用智能神经监督学习网络来识别神经学数据中的模糊趋势。这种新方法可能会改善诊断和治疗方法,并有望提高我们对帕金森病(PD)动力学的理解。通过利用包含多层循环层的体系结构的特征,设计了建议的智能系统神经监督深度学习网络(insdln)。insdln的输入和目标样本是根据参考数据组织和构建的,这些参考数据是使用亚当斯方法在一系列PI场景中制定的,使用可靠的数值求解器进行建模。为了评估对脑电活动模式的影响,这种方法涉及移动传感器的位置。微分方程用于使用Mathematica的ND solve函数创建数据集。insdln训练数据集使用Adam随机求解器生成。之后,该数据集被划分为三个显著状态:80%用于训练,10%用于验证,15%用于测试。这些划分的目的是为了有效地处理动态模型所带来的困难。数据集随机分为训练样本、测试样本和验证样本,用于应用为本研究创建的insdln。为了保证模型在各种数据集上的稳定性和有效性,通过基于均方误差的适应度函数优化来执行分割过程。所提出的insdln通过实现最小均方误差(MSE)、完全回归分析(Rg),证明了准确性、精确性和安全性。As),优化的误差直方图(Err。Hg),误差的自相关(Err的AC),输入与误差的互相关(CCIEr),最小绝对误差(Ab. Er)。在模拟帕金森病脑节律时,INSDLNs优于LMBPA和BRM,误差极低(MSE: 5.86E-12±2.11 e -12),绝对误差接近于零,回归精度强(R2≈0.998)。较低的均方误差(MSE)表明该方法运行有效,模型生成的预测更可靠。达到几乎为零的绝对误差(Ab. Er)为insdln提供了更多证据。这些结果突出了应用insdln和追求最佳解决方案所获得的更高的准确性和预测能力。
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引用次数: 0
Five-class motor imagery BCI classification and its application to brain-controlled wheelchairs. 五类运动意象BCI分类及其在脑控轮椅中的应用。
IF 3.9 3区 工程技术 Q2 NEUROSCIENCES Pub Date : 2026-12-01 Epub Date: 2026-02-03 DOI: 10.1007/s11571-026-10412-8
Hongguang Pan, Bingyang Teng, Zesheng Liu, Shiyu Tong, Xinyu Yu, Zhuoyi Li

Brain-controlled wheelchair (BCW) technology enables direct wheelchair control via brain-computer interfaces (BCIs), eliminating the need for physical limb interaction. Motor imagery-based BCIs (MI-BCIs) are widely used in non-invasive BCIs due to their ability to provide intuitive neural control without external stimuli. However, developing a BCW system based on MI-BCIs remains challenging, particularly in achieving reliable multi-class classification accuracy.To address this challenge, this study proposes an advanced feature extraction algorithm to enhance MI-BCI performance using a custom-built five-class MI-EEG dataset. The proposed method, EHT-CSP, integrates Ensemble Empirical Mode Decomposition Hilbert-Huang Transform (EEMD-HHT) with Time-Frequency Common Spatial Pattern (TFCSP). Specifically, it extracts marginal spectrum entropy and energy spectrum entropy via EEMD-HHT. It then combines these features with TFCSP-derived feature vectors to improve feature discrimination. The Light Gradient Boosting Machine is then employed for classification. The proposed MI-BCI system is evaluated through both offline analysis and real-world BCW obstacle avoidance experiments. Results demonstrate that the algorithm achieves an average classification accuracy of 78.45%, with all participants successfully completing BCW navigation tasks. In this study, LightGBM and EHT-CSP are compared with other algorithms respectively, and it is verified that the proposed model is superior to the existing models.

脑控轮椅(BCW)技术可以通过脑机接口(bci)直接控制轮椅,消除了肢体物理交互的需要。基于运动图像的脑机接口(mi - bci)由于能够在没有外界刺激的情况下提供直观的神经控制,被广泛应用于无创脑机接口。然而,开发基于mi - bci的BCW系统仍然具有挑战性,特别是在实现可靠的多类分类精度方面。为了解决这一挑战,本研究提出了一种先进的特征提取算法,利用定制的五类MI-EEG数据集来提高MI-BCI性能。提出的方法EHT-CSP将集成经验模态分解Hilbert-Huang变换(EEMD-HHT)与时频共空间模式(TFCSP)相结合。具体而言,利用EEMD-HHT提取边际谱熵和能谱熵。然后将这些特征与tfcsp衍生的特征向量相结合,以提高特征识别能力。然后使用光梯度增强机进行分类。通过离线分析和现实世界的BCW避障实验对所提出的MI-BCI系统进行了评估。结果表明,该算法的平均分类准确率为78.45%,所有参与者都成功完成了BCW导航任务。在本研究中,将LightGBM和EHT-CSP分别与其他算法进行了比较,验证了所提模型优于现有模型。
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引用次数: 0
Design and Preliminary Testing of a Lightweight and Low-Cost Knee Exoskeleton For Human Gait Assistance. 轻量化低成本人体步态辅助膝关节外骨骼的设计与初步测试。
IF 0.7 4区 医学 Q4 ENGINEERING, BIOMEDICAL Pub Date : 2026-04-01 Epub Date: 2026-01-14 DOI: 10.1115/1.4069564
Sebastian Barrutia, Christian Knuth, Daniel Ferris

Pediatric exoskeletons have the potential to aid the walking of children with neuromuscular conditions such as crouch gait. However, current exoskeleton devices often rely on bulky batteries and motors. Recent developments in 3D-printing technologies now allow the construction of lightweight yet stiff parts that are easy to customize and use for pediatric applications. We present the mechanical design of a 3D-printed and spring-powered knee exoskeleton for gait assistance. The device had a mass of ∼1.25 kg per leg and provided a knee extensor moment during the stance phase of gait, simulating the spring-like behavior of the knee. Conversely, the exoskeleton provided no resistance during swing to allow free motion of the joint. To validate the device, we recruited two neurologically intact children to walk on a treadmill with and without the exoskeleton while we recorded kinematics, kinetics, and muscle activity data. Our exoskeleton generated knee extensor moments proportional to its angular excursion and had a peak mean moment of ∼0.1 N·m/kg during stance. Kinetic data showed that subjects decreased their biological knee moment and joint spring-like behavior to compensate for the added exoskeleton moment and stiffness, respectively. We ultimately show that the device is robust and capable of generating extensor moments comparable to devices used to assist the knee in children with crouch gait.

儿童外骨骼有可能帮助患有神经肌肉疾病(如蹲姿)的儿童行走。然而,目前的外骨骼设备通常依赖于笨重的电池和马达。3d打印技术的最新发展现在允许构建轻质但坚硬的部件,易于定制和用于儿科应用。我们提出了一种3d打印和弹簧驱动的膝关节外骨骼的机械设计,用于步态辅助。该装置每条腿的质量约为1.25 kg,并在步态的站立阶段提供膝关节伸肌力矩,模拟膝关节的弹簧行为。相反,外骨骼在摆动时不提供阻力,允许关节自由运动。为了验证该装置,我们招募了两名神经系统完好的儿童,让他们在跑步机上行走,同时记录运动学、动力学和肌肉活动数据。我们的外骨骼产生的膝关节伸肌力矩与其角度偏移成正比,在站立期间的峰值平均力矩为~ 0.1 N·m/kg。动力学数据显示,受试者减少了他们的生物膝关节力矩和关节弹簧样行为,以补偿增加的外骨骼力矩和刚度。我们最终表明,该装置是坚固的,能够产生伸肌力矩,可与用于辅助儿童蹲伏步态的设备相媲美。
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